更新于：2024-11-01

Nails, Ingrown

嵌甲

更新于：2024-11-01

基本信息

别名

Embedded toenail、IGTN - Ingrowing toenail、INGROWN NAIL

+ [64]

简介

Excessive lateral nail growth into the nail fold. Because the lateral margin of the nail acts as a foreign body, inflammation and granulation may result. It is caused by improperly fitting shoes and by improper trimming of the nail.

关联

项与嵌甲相关的药物

Acetylcysteine

乙酰半胱氨酸

靶点

Free radicals

作用机制

自由基抑制剂

在研机构

原研机构

在研适应症

非在研适应症

最高研发阶段批准上市

首次获批国家/地区

美国

首次获批日期1963-09-14

M-1210

靶点-

作用机制-

在研机构-

原研机构

Maruho Co., Ltd.

在研适应症-

非在研适应症

嵌甲

最高研发阶段无进展

首次获批国家/地区-

首次获批日期1800-01-20

项与嵌甲相关的临床试验

ChiCTR2400089982 / Suspended早期临床1期IIT

A clinical evaluation study of flexible tube under the ingrown nail combined with nail reconstruction in the treatment of onychocryptosis with paronychia

开始日期2024-10-01

申办/合作机构-

NCT06266208 / CompletedN/AIIT

Utility of High-resolution Ultrasound to Evaluate Dorsal Osteophyte Associated With Onychocryptosis: Correlation With Radiology.

This study will evaluate the usefulness of ultrasonography in detecting dorsal osteophytes associated with claw nails compared to radiographs. The hypothesis will be that the larger the size of the osteophyte, the greater the nail curvature.
Nail curvature and osteophyte height will be measured in patients with clamp nails. Nail-phalange distance will also be measured with radiography and ultrasonography.
The investigators to find a positive correlation between nail curvature and osteophyte height. Furthermore, a strong agreement is expected between both imaging techniques to measure nail-phalange distance.
Ultrasonography could constitute a safe and effective alternative to radiology for detecting dorsal osteophytes in claw nails, especially in mild cases, follow-ups or young patients.

开始日期2024-03-20

申办/合作机构

Universidad Católica de Valencia San Vicente Mártir

NCT06306105 / CompletedN/A

Assessment of Anti-aging Efficacy of Marine Collagen Peptides

To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human

开始日期2024-03-04

申办/合作机构

大江生医股份有限公司

100 项与嵌甲相关的临床结果

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100 项与嵌甲相关的转化医学

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0 项与嵌甲相关的专利（医药）

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239

项与嵌甲相关的文献（医药）

2024-09-01·Actas Dermo-Sifiliográficas

Enfermedad ungueal congénita y hereditaria

Review

作者: Gilaberte Calzada, Y ; Matei, M C ; Bernal Masferrer, L ; Navarro Campoamor, L

Nail disorders in newborns can show independently or as components of systemic illnesses or genodermatoses. The examination of these abnormalities is complex and sometimes challenging. However, familiarity with these disorders can significantly contribute to uncovering potential underlying conditions. This review includes the physiological nail changes seen within the first few months of life, such as Beau's lines, onychoschizia, koilonychia, congenital nail fold hypertrophy of the first digit, and onychocryptosis. This review also focuses on the most relevant congenital disorders reported and how to perform differential diagnosis. Finally, this review highlights those hereditary diseases in which nail involvement is crucial for diagnosis, such as nail-patella syndrome, congenital pachyonychia, or congenital dyskeratosis, among others.

2024-09-01·Actas Dermo-Sifiliográficas

[Translated article] Congenital and Hereditary Nail Disease

Review

作者: Gilaberte Calzada, Y ; Matei, M C ; Bernal Masferrer, L ; Navarro Campoamor, L

2024-06-01·Journal of Foot and Ankle Research

A survey of the treatment and management of ingrown toenails by UK podiatrists: A cross‐sectional survey

Article

作者: Jones, Katherine ; Watson, Judith ; Backhouse, Michael ; Exley, Victoria

AbstractBackgroundIngrown toenails are a common pathology. Although a range of conservative and surgical measures are widely used for this condition, little is known about their use in practice. This study explored current practice relating to the treatment or management of ingrown toenails by podiatrists in the UK.MethodsA cross‐sectional online survey (Qualtrics, Provo, UT, USA) conducted between March to June 2020 was distributed to practicing podiatrists treating or managing ingrown toenails in the UK.ResultsA total of 396 practicing podiatrists responded (60.1% based in the private sector). The majority (88.6%) performed nail surgery most commonly (54.3%) less than five a month. Nearly all (95%) only performed nail avulsion with or without chemical matrixectomy, universally using phenol (97.2%). Application time and number of applications varied but was most commonly applied three times (61.5%) for a total of 3 minutes (75%). Aftercare varied considerably between public and private sectors, with public sectors offering fewer follow‐up appointments.ConclusionsAlthough there is a variation in clinical practice throughout the treatment pathway, almost all respondents offered nail avulsion with phenol matrixectomy, whereas very few provided incisional nail surgery. This data provides the most comprehensive description of how UK podiatrists conduct nail surgery for onychocryptosis.