更新于：2024-09-19

Flatfoot

扁平足

更新于：2024-09-19

基本信息

别名

'Rocker bottom' feet、'Rocker-bottom' feet、Acquired Adult Flatfoot Deformity

+ [113]

简介

Progressive acquired flatfoot in which the arch of the foot is flat only when standing. It is often caused by POSTERIOR TIBIAL TENDON DYSFUNCTION.

关联

项与扁平足相关的药物

Chloroprocaine Hydrochloride

盐酸氯普鲁卡因

靶点

Sodium channels

作用机制

钠通道阻滞剂

在研机构

Fresenius Kabi USA LLC [+4]

原研机构

Fresenius Kabi AG

在研适应症

麻醉 [+4]

非在研适应症

白内障

最高研发阶段批准上市

首次获批国家/地区

美国

首次获批日期1955-03-11

197

项与扁平足相关的临床试验

NCT06401954 / Not yet recruitingN/AIIT

Effects of High-Intensity Focused Electromagnetic Therapy Combined With Foot Core Training on Dynamic Foot Function in Individuals With Pronated Foot

The objective of this trial is to assess the effects of high-intensity focused electromagnetic therapy combined with foot core training targeting the intrinsic foot muscles on plantar load, static foot posture, intrinsic foot muscle morphology and intrinsic foot muscle activation in individuals with pronated foot.
The main questions it aims to answer are:
Question 1: To compare changes in plantar load following interventions of high-intensity focused electromagnetic therapy combined with foot core training, high-intensity focused electromagnetic therapy alone, and sham high-intensity focused electromagnetic therapy combined with foot core training.
Question 2: To compare changes in static foot posture, intrinsic foot muscle morphology, and intrinsic foot muscle activation following interventions of high-intensity focused electromagnetic therapy combined with foot core training, high-intensity focused electromagnetic therapy alone, and sham high-intensity focused electromagnetic therapy combined with foot core training.
Question 3: To assess the effects of each intervention on plantar load, static foot posture, intrinsic foot muscle morphology, and intrinsic foot muscle activation in individuals with pronated foot.
Participants will undergo stimulation of their intrinsic foot muscles through high-intensity focused electromagnetic therapy, and they will also be required to isometrically contract their intrinsic foot muscles during the designated exercise program. Researchers will assess the effects of high-intensity focused electromagnetic therapy combined with foot core training by evaluating plantar load during walking, static foot posture, intrinsic foot muscle morphology and intrinsic foot muscle activation during walking.

开始日期2024-05-15

申办/合作机构

National Taiwan University Hospital

NCT06389253 / Not yet recruitingN/AIIT

Subtalar Extra-articular Screw Arthroereisis: How Does the Screw Work

The aim of the study is to investigate the effect of subtalar extra-articular calcaneo-stop screw on the proprioceptive and nociceptive pathways of the ankle before and after implantation. The hypothesis of the study is that an increased number of receptors related to proprioception will be detected in the sinus tarsi.

开始日期2024-05-01

申办/合作机构

Università Vita-Salute San Raffaele

NCT06211504 / Recruiting临床4期

Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity: a Randomized Controlled Trial

Background: Adult acquired flatfoot deformity (AAFD) is a deformity of the foot which leads to pain and an altered gait pattern. There are several different surgical interventions available for treatment of AAFD. One of the most common treatments for mobile AAFD is medial displacement calcaneal osteotomy (MDCO) with or without adjuvant soft tissue procedures. However, the medial displacement of the calcaneus only aims to correct the deformity in one plane despite AAFD being a deformity of three planes with hypereversion of the calcaneus, anterior translation of the talus over the calcaneus and tilting/drop of the calcaneal head. Because of these multiple forces, the healing of MDCO in the intended position can sometimes be hard to achieve and medial soft tissue is still stressed leading to recurring deformity. The investigators believe that adjuvant insertion of a sinus tarsi implant (STI) could work as an internal splint, protecting soft tissue procedures on the medial side, reversing anterior translation of the talus, opposing calcaneus eversion, and lifting talar head. This additional procedure will create a better correction of the deformity with enhanced appearance of the foot and better long-term functional results.
Methods: This is a multi-center randomized controlled trial designed to assess the efficacy of STI as an adjuvant procedure to MDCO in patients with mobile AAFD (Stage IIA). Patients aged 16 to 75 years, referred to one of the orthopedic centers involved in this study, will be invited to participate if they fulfil the trials eligibility criteria. In total, 130 patients who provide informed consent will be randomized to either MDCO with STI or MDCO without STI (65 patients in each group). The included patients will be clinically and radiographically examined. They will also fill out a form before surgery and 4-5 months, 1 year and 2 years postoperatively. The form will include Self-Reported Foot and Ankle Score (SEFAS) and Euro-QoL 5 Dimensions (EQ-5D). The trials primary outcome will be change in Meary's angle. Secondary outcomes include additional radiographic changes, change in SEFAS score, EQ-5D index, pain according to visual analog scale (VAS), satisfaction assessment, clinical outcome measures, the length of postoperative sick-leave and rate of complications.
Discussion: This is the first randomized controlled trial assessing the efficacy of a sinus tarsi implant as an adjuvant procedure to MDCO.

开始日期2024-04-11

申办/合作机构

Region Skåne Holding AB

100 项与扁平足相关的临床结果

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100 项与扁平足相关的转化医学

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0 项与扁平足相关的专利（医药）

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3,753

项与扁平足相关的文献（医药）

2024-02-14·International journal of stroke : official journal of the International Stroke Society

Dabigatran etexilate versus warfarin in cerebral venous thrombosis in Chinese patients (CHOICE-CVT): an open-label, randomized controlled trial.

Article

作者: Hongrui Ma ; Yaqin Gu ; Tingting Bian ; Haiqing Song ; Zhi Liu ; Xunming Ji ; Jiangang Duan

BACKGROUND:

The efficacy and safety of dabigatran etexilate for Chinese patients with cerebral venous thrombosis (CVT) has not been well established.

METHODS:

CHOICE-CVT was an exploratory, single-center, randomized, open-label study in the National Center for Neurological Disorders involving Chinese patients with CVT aged 18 to 80 years who were randomly assigned (1:1) to either dabigatran etexilate or warfarin. Oral anticoagulants were initiated after 10-15 days of LMWH. The primary efficacy and safety endpoints included the number of patients with recurrent CVT and/or deep venous thrombosis (DVT) and major clinical bleeding within 180 days. Secondary efficacy endpoints included venous recanalization and change in papilledema at day 180. Secondary safety outcomes comprised death, clinical non-major bleeding, and any bleeding. The study was registered with ClinicalTrials.gov under NCT03930940.

RESULTS:

Between October 2017 and February 2023, a total of 89 patients were enrolled and randomly assigned to receive either dabigatran etexilate (n=44) or warfarin (n=45). At day 180, the dabigatran etexilate group showed a statistically non-significant but likely clinically significant number of patients with recurrent CVT and/or DVT (8 [18.2%; 95%CI, 6.3-30.0] vs 3 [6.7%; 95%CI, 0.0-14.2], P=0.099, with a power [1-β] of 38.401%) compared to the warfarin group. The dabigatran etexilate group showed a comparable number of patients with clinical major bleeding (0 [0] vs 0 [0], P=1.000), and clinical non-major bleeding (1 [2.3%; 95%CI, 0.0-6.9] vs 1 [2.2%; 95%CI, 0.0-6.7]) but demonstrated a lower risk of any bleeding (1 [2.3%; 95%CI, 0.0-6.9] vs 9 [20.0%; 95%CI, 7.8-32.2]) compared to the warfarin group. Most patients in both groups achieved venous recanalization according to the Modified Qureshi scale (27 [75%; 95%CI, 60.1-89.9] in the dabigatran etexilate group versus 34 [82.9%; 95%CI, 70.9-95.0] in the warfarin group) and exhibited improvement in papilledema as per the Frisén classification (35 [97.2%; 95%CI, 91.6-100.0] in dabigatran etexilate group vs. 37 [88.1%, 95%CI, 77.9-98.3] in warfarin group).

CONCLUSIONS:

These findings regarding efficacy and safety support the consideration of dabigatran etexilate therapy as a viable treatment option for Chinese patients with CVT.

2024-02-09·European journal of pediatrics

Exploring flatfeet morphology in children aged 6-12 years: relationships with body mass and body height through footprints and three-dimensional measurements.

Article

作者: Zi-Yu Feng ; Jing-Yi She ; Xin-Yao Hu ; Hong-Sheng Liu ; Hua-Jun Wang ; Li-Guo Zhu ; Sheng Zheng ; Jian-You Li ; Kai-Rui Zhang ; Yi-Kai Li ; Chao Chen

The aim of the study was to determine the relationship between flatfoot morphology and body mass and height in children aged 6-12 years. A total of 6471 Chinese children (mean age 9.0 ± 1.9 years, 41% female) were assessed for foot morphometry, body height, and body mass index. Foot morphology, including foot length, width, girth, arch height, hallux valgus angle, and rearfoot valgus angle, was measured using a 3D laser scanner. Flatfoot evaluations were conducted using the Sztriter-Godunov index (KY) from footprints. All measurements were analyzed by age and sex using the mean values of the left and right sides. Comparisons were performed between flatfoot groups, between body mass index (BMI) groups, and between body height groups. The study revealed a significant decrease in the incidence of bipedal flatfoot with age (p < 0.001), whereas the prevalence of obesity remained consistent (p > 0.05). Bipedal flatfoot was associated with distinct morphological changes, including lower arches, reduced instep height, diminished ankle heights and a greater rearfoot valgus angle (p < 0.05). When comparing the BMI groups, overweight children had larger and thicker feet (p < 0.05), but no differences were found in arch height and ankle height (p > 0.05). When comparing the body height groups, short-statured children had a shorter feet girth, shorter arches, and shorter ankle height (p < 0.05), but no differences were found in the rearfoot valgus angle (p > 0.05).

CONCLUSION:

The main characteristics of flat feet include lower arches and instep heights and ankle heights but higher rearfoot valgus angles. In general, overweight children's feet do not have the common features of flat feet. In contrast, short children had similar features of flatfoot except for rearfoot valgus. Assessment of posture, such as rearfoot valgus, can be critical in identifying children with flat feet.

WHAT IS KNOWN:

• The morphology of children's feet is associated with body growth, but the relationship between flatfeet and body mass and height remains controversial.

WHAT IS NEW:

• Three-dimensional foot measurement shows that body mass is generally not associated with flatfeet, while short children have lower arches but no rearfoot valgus.

2024-02-08·BMC sports science, medicine & rehabilitation

Investigation of inter-rater and test-retest reliability of Y balance test in college students with flexible flatfoot.

Article

作者: Yalin Zheng ; Renzhi Feng ; Weiyin Hu ; Peng Huang

BACKGROUND:

The Lower Quarter Y Balance Test (YBT-LQ) has been widely used to assess dynamic balance in various populations. Dynamic balance in flexible flatfoot populations is one of the risk factors for lower extremity injuries, especially in college populations in which more exercise is advocated. However, no study has demonstrated the reliability of the YBT-LQ in a college student flexible flatfoot population.

METHODS:

A cross-sectional observational study. 30 college students with flexible flatfoot were recruited from Beijing Sports University. They have been thrice assessed for the maximal reach distance of YBT under the support of the lower limb on the flatfoot side. Test and retest were performed with an interval of 14 days. The outcome measures using the composite score and normalized maximal reach distances in three directions (anterior, posteromedial, and posterolateral). The relative reliability was reported as the Intraclass Correlation Coefficient (ICC). Minimal Detectable Change (MDC), Smallest worthwhile change (SWC), and Standard Error of Measurement (SEM) were used to report the absolute reliability.

RESULTS:

For inter-rater reliability, the ICC values for all directions ranged from 0.84 to 0.92, SEM values ranged from 2.01 to 3.10%, SWC values ranged from 3.67 to 5.12%, and MDC95% values ranged from 5.58 to 8.60%. For test-retest reliability, the ICC values for all directions ranged from 0.81 to 0.92, SEM values ranged from 1.80 to 2.97%, SWC values ranged from 3.75 to 5.61%, and MDC95% values ranged from 4.98 to 8.24%.

CONCLUSIONS:

The YBT-LQ has "good" to "excellent" inter-rater and test-retest reliability. It appears to be a reliable assessment to use with college students with flexible flatfoot.

TRIAL REGISTRATION:

This trial was prospectively registered at the Chinese Clinical Trial Registry with the ID number ChiCTR2300075906 on 19/09/2023.

项与扁平足相关的新闻（医药）

2023-08-28

·美通社

美中宜和骨科运动康复医学助力2023北京城市副中心夜跑顺利完赛

北京 2023年8月28日 /美通社/ -- 8月26日，由北京市通州区人民政府主办，北京市通州区体育局、区残联、北投体育、绿心园林、世搏体育承办的通通来运动 2023"大运河之夜"北京城市副中心夜跑活动在通州区城市绿心森林公园开跑。美中宜和骨科运动康复医学作为赛事官方医疗合作伙伴，助力夜跑顺利完赛。本次夜跑活动以城市绿心活力汇为起终点，近千人围绕城市绿心森林公园内星型环路夜跑，一路上荧光饰品闪亮，欢声笑语不断。大家通过无速度之争的夜跑，全身心的体验运动快乐，感受活动氛围，同时又近距离的欣赏了城市副中心的魅力夜景。夜跑活动参与人员是来自各行各业的跑步爱好者，尽管活动以不竞速的路跑为特点，但跑步本身有可能会带来一定的运动损伤风险，赛事医疗保障显得尤为重要。美中宜和医疗作为此次夜跑活动的官方医疗合作伙伴，由骨科/运动康复医学专业医护团队驻守现场，为参赛人员全程提供医疗保障，为出现运动损伤的参赛者提供及时的专业救治和护理，确保夜跑活动能够安全完赛。除了提供医疗支持，美中宜和医疗站也成为大家咨询健康问题的聚集地。随着近几年全民健康意识的增强，运动健身的热情也愈发高涨。运动之外带来的运动损伤等问题也开始受到大家的关注，对于常见的崴脚、关节疼痛、半月板损伤、扁平足等等问题成为大家咨询的热点。骨科医生和康复师就大家关心的问题也给予了耐心地解答，让参赛者在体验夜跑乐趣的同时也丰富了自己的医学知识。本次夜跑活动期间，主办方还精心准备了夜跑嘉年华，参与者热情参与了丰富多彩的全民健身体验项目和抽奖环节，在夜跑互动过程中增添了诸多乐趣。

2023-02-13

·PRNewswire

Sham J. Persaud, DPM is recognized by Continental Who's Who

WASHINGTON, Pa., Feb. 13, 2023 /PRNewswire/ -- Sham J. Persaud, DPM, is being recognized by Continental Who's Who as a Distinguished Healthcare Professional in the Medical field. Continue Reading Sham J. Persaud Dr. Persaud completed a Bachelor of Science degree with a Minor in Chemistry at St. Leo University, graduating cum laude in 2010. He earned a DPM degree in 2015 from Rosalyn Franklin University in Chicago, IL. Dr. Persaud completed a podiatric residency in 2018 at West Penn Foot and Ankle Institute (Allegheny Health Network). He then completed a Foot and Ankle Trauma and Reconstruction Fellowship at Mon Valley Hospital in 2019. The doctor is board qualified in foot and ankle reconstruction and surgery and provides foot and ankle surgeries to patients suffering from severe trauma. Dr. Persaud previously worked at the East Orange VA Medical Center and is now at Advanced Orthopaedics and Rehabilitation. According to the doctor, he meets with patients and examines them to determine their diagnosis and treatment plan in his day-to-day work. He performs ankle and foot surgeries, usually to fix the results of a traumatic injury. He has personal experience with trauma injuries and is passionate about helping his patients regain foot and ankle function and helping them recover as quickly as possible. Dr. Persaud has an active affiliation with the American College of Foot and Ankle Surgeons, the American Podiatric Medical Association, and the American Society of Podiatric Surgeons. Dr. Persaud also examines patients for other podiatric conditions, such as flat feet, heel pain/spurs, plantar fasciitis, athletic injuries, ankle sprains, neuroma/pinched nerves, and hammertoes. He notes that the facility has the latest treatments for foot healthcare, including in-office x-rays, platelet-rich plasma therapy, bracing, custom prescription orthotics, and both hospital and in-office surgery. Dr. Persaud was recognized by Health News Today in 2022 for his excellent work in the Medical Field and is the recipient of various prestigious awards in the field, including the 2018 ACFAS Poster Award Winner, Dr. Phillip R. Brachman Alumni Association Scholarship, and the Schill Distinguished Scholar Award. He dedicates this honorable recognition to his mentors, Mark Hofbauer, DPM, Alan Catanzariti, DPM, and Arthur Valadie, MD. He would also like to thank his fiancé and his family for all their love and support. For more information, visit persaudfootandankle.com. Contact: Katherine Green 516-825-5634 [email protected] SOURCE Continental Who's Who

高管变更

2023-01-31

·PRNewswire

RedPoint Medical 3D Announces Weight Bearing CT, When Available, is Preferred Input for Its Surgical Planning Solution

HATFIELD, Penn., Jan. 31, 2023 /PRNewswire/ -- RedPoint Medical 3D (RPM-3D) announced that when available, weight bearing computed tomography (WBCT) imaging is the preferred imaging input for its advanced surgical planning tools and patient-specific cut guides. RPM-3D's groundbreaking technology converts computed tomography (CT) scan data into a manipulatable 3D model using proprietary AI-enabled auto segmentation software, IntelliPrint 3D printed anatomic maps (BoneClone™) and the surgeon's input to perform a full digital rehearsal of the deformity correction leading up to the actual surgery. A 3D printed patient-specific cutting guide is provided along with customized instrumentation to help achieve a flawless execution of the planned surgical correction. RPM-3D requires advanced 3D imaging to build accurate anatomic models necessary for its planning process. Standard weight-bearing X-Ray data alone is not sufficient to produce detailed anatomic mapping. Since its introduction in 2012, WBCT imaging is gaining ground as a modality of choice to best evaluate foot and ankle conditions including hallux valgus (bunions), progressive collapsing foot disorder (flat foot), complex angular deformities of the hindfoot and ankle, and functional assessments of traumatic injuries such as syndesmotic (high ankle sprain) pathology. RPM-3D recognizes this modality as a preferred data input for its planning process when available. "WBCT imaging is a necessary step into the future of advanced deformity correction planning due to its ability to capture the influence of gravity on a symptomatic anatomic segment," said Adam D. Perler, DPM FACFAS, co-founder and Chief Innovation Officer for RPM-3D. Patients stand fully upright in a WBCT scanner, allowing bone and joint alignment to be appreciated in a 3D functional position. Conventional medical CT (MDCT) imaging systems scan the patient while they are laying down (in supine position). While the output data of MDCT is three dimensional in nature, accurate biomechanical alignment of the patient's anatomy cannot be appreciated. CurveBeam AI's HiRise WBCT imaging system can scan the entire legs, including hips and pelvis, while the patient is standing upright. Several surgeons currently using RPM-3D incorporate CurveBeam AI WBCT technology in their surgical planning for deformity corrections. RPM-3D received FDA 510(k) clearance in June of 2022 for its psi-based Intelliguide™ system which includes the Better Bunion family, a patient-specific bunion surgical planning system. RPM-3D provides custom surgical planning and cut guides for bone osteotomies and deformity reductions for both adult and pediatric patients to the age of 13. Visit CurveBeam AI at Booth #535 and RedPoint Medical 3D at Booth #1212 at the ACFAS 2023 Scientific Conference in Los Angeles, February 9 -12, 2023. About RedPoint Medical 3D Visit About CurveBeam AI CurveBeam AI specializes in cone beam CT imaging and complementary AI applications for orthopedics and bone health. CurveBeam AI's global operations headquarters for product development, Regulatory, manufacturing and operations including marketing, sales and customer care are in Hatfield PA, USA. CurveBeam AI's corporate office in Melbourne, VIC, Australia, covers AI research & development, corporate finance, and IP functions. CurveBeam AI, which has more than 50 employees, is an unlisted Australian public company backed by several major professional investors and is targeting an Initial Public Offering in 2023. SOURCE CURVEBEAM AI; RedPoint Medical