Idebenone

2026年10月16日，中华医学会2026年度皮肤科实验研究（第十届）学术会议（CSID 2026）各分会场顺利举行。 上午场共设6个分会场，分别聚焦银屑病免疫机制与转化研究、皮肤基因组与表皮屏障及毛发、银屑病发病机制与临床研究及免疫代谢与治疗靶点、特应性皮炎发病机制与治疗进展、适应性免疫与自身免疫及结缔组织病、色素性皮肤病等方向。来自全国多家医疗机构及高等院校的专家学者围绕前沿进展与临床转化展开深入交流。 “Psoriasis: Immune Mechanisms and Translational Research”银屑病专题分会场顺利举行，分为Session 1与Session 2两个单元。本专场聚焦银屑病发病免疫机制、基础研究创新成果与临床转化前沿，国内银屑病领域专家学者云集，围绕银屑病发病机制、靶点挖掘与诊疗策略优化展开深入交流。 专场第一部分由上海市皮肤病医院王秀丽教授和上海交通大学医学院附属仁济医院鞠强教授共同主持。复旦大学附属华山医院于宁教授以“From snapshot to trajectory-new insight into psoriasis longitudinal data”为题作报告，西安交通大学第二附属医院耿松梅教授以“The role of mast cells in psoriasis inflammation”为题进行交流，空军军医大学西京医院白亚星医师以“Nicotine reprograms neutrophil metabolism and epigenetics to drive psoriasis pathogenesis”为题进行分享，绍兴市人民医院鲍艳秋医师以“Hypothyroidism Exacerbates Psoriasis-like Inflammation by Inducing a UAP1-high Fibroblast Phenotype”为题作报告，浙江大学医学院附属第二医院曹华莉医师以“Psoriasis microenvironment remodeling: advances, challenges, and perspectives on nanozyme and microbial platforms”为题进行交流，上海交通大学医学院附属仁济医院颜丝余医师以“Keratinocyte-derived PLA2G4D participates in psoriasis recurrence by regulating CXCL13⁺CD8⁺ T cell responses”为题进行分享，中南大学梁小伟医师以“Chemical De-Noising of Dithranol Yields YNF with Improved Tolerability and Unmasks VCP-Linked Antipsoriatic Pharmacology”为题作报告，华中科技大学同济医学院附属协和医院陈梦姣医师以“A distinct psoriasis-atopic dermatitis overlapping phenotype in adults with dual type 2 and type 3 immune features and favorable response to JAK1 inhibition”为题进行交流，中国医科大学附属盛京医院成将伟医师以“Eicosapentaenoic Acid Ameliorates Psoriasis-like skin inflammation by Regulating Keratinocyte Lipid Metabolism and Proliferation via the ACLY–CTNNB1 Axis”为题进行分享。 专场第二部分由空军军医大学西京医院党二乐教授和上海市皮肤病医院邹颖教授共同主持。四川大学华西医院代盈盈医师以“Cross-study analysis of reproductive hormone-related transcriptional programs in psoriasis”为题作报告，中南大学湘雅医院方驰医师以“CeO₂ Nanozyme Reprograms Keratinocyte Glycolipid Metabolism to Alleviate Psoriasis and Disrupt Inflammatory Memory”为题进行交流，西安交通大学第二附属医院冯乐遥医师以“Endophilin A2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice”为题进行分享，四川大学华西医院Hongli Wang医师以“GRAPPA versus EULAR definitions for difficult to treat psoriatic arthritis: concordance and baseline predictors based on the PARWCH cohort”为题作报告，南京大学医学院附属金陵医院周楠医师以“Engineering a Sulfur-Coordinated Iron Single-Atom Nanozyme Hydrogen that Reshapes Redox Microenvironment and Suppresses Psoriatic Inflammation”为题进行交流，天津医科大学总医院侯舒旗医师以“Mechanistic investigation into KMT5A-mediated regulation of psoriasis-like inflammation and screening for KMT5A inhibitors”为题进行分享，厦门大学胡霄医师以“WNT-Mediated Adipocyte Reprogramming Restores Homeostasis in Psoriatic Skin”为题作报告，中国科学技术大学附属第一医院（安徽省立医院）许金亮医师以“Validation of the Diagnostic Performance of the Chinese Version of the Psoriasis Epidemiology Screening Tool (PEST) for Psoriatic Arthritis: A Cross-Sectional Study”为题进行交流，中国医科大学附属第一医院张丽教授以“Stapokibart for Optimal Long-Term Control of Atopic Dermatitis”为题进行分享。本次专场兼顾基础创新与临床转化，从多维度解析银屑病发病机制，集中展示了银屑病免疫机制与转化研究领域的最新成果，为推动学术交流与临床转化提供了重要平台。 “皮肤基因组、表皮屏障与毛发”及“银屑病的机制与治疗研究”专场在一层富悦5厅顺利举行。本专场聚焦皮肤基因组、表皮屏障与毛发疾病，以及银屑病的机制与治疗研究，内容涵盖基础研究、临床诊疗及治疗策略探索。 专场第一部分“皮肤基因组、表皮屏障与毛发”由浙江大学医学院附属第二医院吕中法教授和解放军南部战区总医院杨慧兰教授共同主持。北京大学第三医院王文慧教授以“Resolving puzzles - New advancements in the treatment of hidradenitis supurativa”为题作报告，北京大学人民医院周城教授以“Taming the Serpent: Practical Diagnosis and Management of Ophiasis”为题进行交流，东莞市人民医院田芮奇医师以“Skin microecology-lipid axis: maintaining barrier homeostasis, driving skin diseases, and intervention strategies”为题进行分享，复旦大学附属华山医院王洁茗医师以“Loss of COL17 Fuels Inflammatory Senescence in Skin: A Putative Basement Membrane Brake on Aging”为题作报告，宁波大学附属第一医院曹巧玉医师以“Overlapping Xq13.3 duplications define an X-linked hypotrichosis simplex and implicate TAB3 dosage sensitivity”为题进行交流，南方医科大学皮肤病医院吕昆仑医师以“Loss-of-function variants in EPHX3 cause nonsyndromic epidermal differentiation disorders”为题进行分享，空军军医大学唐都医院曹天宇医师以“SIRT7 attenuates androgenetic alopecia progression via deacetylation of the androgen receptor and suppression of oxidative stress”为题作报告，昆明医科大学第一附属医院贾肖蓉医师以“Deciphering the Heterogeneity of Fibroblasts in Melasma and Their Molecular Mechanisms in Regulating Melanin Metabolism Based on Single-Cell Transcriptomics”为题进行交流。 专场第二部分“银屑病的机制与治疗研究”由厦门大学张凌娟教授和重庆医科大学附属第一医院陈爽教授共同主持。空军军医大学第一附属医院刘婉婷医师以“METTL7A-Dependent m6A Methylation Orchestrates CXCR4hi Neutrophil Pathogenicity and NETosis in skin inflammation”为题作报告，浙江大学医学院附属邵逸夫医院王思佳医师以“Langerhans-cell-focused divergence and IL-12/23 axis suppression distinguish Deucravacitinib from Tildrakizumab in psoriasis: a paired single-cell interaction analysis”为题进行交流，北京大学第三医院彭芬医师以“Mechanism of the CGRP-IL-17C Self-Sustaining Inflammatory Amplifier in Biologic-Induced Immune skewing in Psoriasis”为题进行分享，中山大学孙逸仙纪念医院蒋卓育医师以“ROS-Responsive Nanoparticle-Loaded Dissolving Microneedles Enable Local Piezo1 siRNA Delivery for Mechanotransduction-Driven Psoriasis”为题作报告，山东大学齐鲁医院曹颖医师以“Target Prediction and Pathway Analysis of Herbal Small-Molecule Compounds Intervening in Psoriasis and Methotrexate-Induced Hepatotoxicity”为题进行交流，解放军总医院第一医学中心佟馨医师以“Xiaoban Yuyin Formula prevents psoriasis relapse via Fabp5-dependent reduction of TRM17 cells”为题进行分享。本次专场展示了皮肤基因组、表皮屏障、毛发疾病及银屑病机制与治疗研究领域的最新进展，为推动学术交流与临床转化提供了重要平台。 “银屑病：发病机制与临床研究”专场暨“银屑病：免疫代谢与治疗靶点”专场在分会场3-三层群贤1厅顺利举行。本专场聚焦银屑病基础发病机制、免疫代谢调控与精准治疗靶点，来自全国各地的皮肤科专家围绕前沿进展与临床实践展开深入交流。 专场第一部分由首都医科大学附属北京朝阳医院刘方教授和同济大学附属皮肤病医院郭春源教授共同主持。北京大学人民医院赵琰教授以“Metabolic Reprogramming Regulates Cytokine Networks in Cutaneous Inflammation”为题作报告，中山大学附属第三医院冯佩英教授以“Human Host Adaptive Evolution of Microsporum canis”为题进行交流，南京医科大学第一附属医院王雨霏医师以“Psoriatic Inflammation Exacerbates Respiratory Infections: Insights from Population Cohorts, Genetic Analyses, and Mouse Models”为题进行分享，天津医科大学总医院魏晶晶医师以“Targeting POLR3G Suppresses R-Loop Formation in Keratinocytes to Alleviate Psoriasis”为题作报告，福建医科大学附属漳州市医院肖翠容医师以“ACSL4-Driven Ferroptosis Dysfunction Mediates Inflammatory Injury and Clinical Progression in Generalized Pustular Psoriasis”为题进行交流，浙江大学医学院附属第二医院徐凡医师以“Keratinocyte-derived CXCL10 promotes osteoclastogenesis from periarticular CD14hi macrophages”为题进行分享，上海市东方医院徐倩楠医师以“Preliminary Exploration of Photoconverted Skin Cell Migration to Peripheral Blood Induced by 405 nm Laser and Its Potential Application in Psoriasis Research”为题作报告，上海市皮肤病医院徐抑非医师以“Who bears the burden of living with psoriasis: A multicenter real-world clinical cohort study”为题进行交流。 专场第二部分由浙江大学医学院附属邵逸夫医院程浩教授和北京大学人民医院赵琰教授共同主持。大连医科大学附属第一医院张书萌医师以“Brusatol ameliorates psoriatic dyslipidemia by targeting IL-1β to restore AMPK-mediated lipid homeostasis”为题作报告，山东第一医科大学附属省立医院闫建军医师以“Risk of Hepatitis B Reactivation in Psoriasis Patients Treated with Biological therapy: A Meta-analysis”为题进行交流，山东第一医科大学附属省立医院阎珍珍医师以“Soluble GPNMB quells psoriatic inflammation by breaking itaconate auto-amplification”为题进行分享，西安交通大学医学部第一附属医院杨舒同医师以“Emodin Ameliorates Psoriasis Through Regulation of IFN-γ-Related Responses and NET Formation”为题作报告，中南大学湘雅二医院尹欢医师以“HDAC6 Attenuates Keratinocyte Proliferation via Ac-α-Tubulin-KIF26A Axis in Psoriasis”为题进行交流，上海市皮肤病医院俞茜医师以“SLC6A14 Rewires Amino Acid Metabolism to Sustain mTOR Signaling in the Psoriatic Epidermis”为题进行分享，浙江大学医学院附属第二医院张凤飞医师以“Tryptophanyl-tRNA synthetase Induces Psoriasis-Like Skin by Facilitating Monocyte/Macrophage Recruitment and Activation”为题作报告，复旦大学附属华山医院张萌萌医师以“ADAM17-Mediated Glycoprotein V Shedding Drives Platelet Activation in Psoriasis and Underlies the Therapeutic Effect of Methotrexate”为题进行交流，山东第一医科大学附属省立医院张敏医师以“LCN2-Driven Fibroblast Ferroptosis-Associated Injury Promotes Keratinocyte Proliferation via Lipid Peroxidation Signaling in Psoriasis”为题进行分享。本次专场内容涵盖银屑病代谢重编程、免疫细胞调控、微生物感染、生物制剂安全性及天然药物干预等多个前沿方向，充分展示了该领域的最新研究成果与临床诊疗经验，为推动学术交流与临床水平提升提供了重要平台。 “Atopic Dermatitis: Pathogenesis and Therapeutic Advances”专场于三层群贤厅2隆重举行。本专场聚焦特应性皮炎、神经免疫、屏障菌群、环境因素、靶向治疗与临床转化等前沿热点，分为两个场次展开深入交流。 专场第一部分由南通大学附属医院陈晓栋教授和南方医科大学南方医院郑跃教授共同主持。中南大学湘雅二医院吴海竞教授以“Basic Research and Translational Medicine of Lupus: Updated Progress by Our Team”为题作报告，昆明医科大学第二附属医院曹文婷教授以“Effects of ultraviolet phototherapy on skin aging in SKH-1 hairless mouse atopic dermatitis model”为题进行交流，安徽医科大学第一附属医院董丽萍医师以“Gold Nanoparticles-Embedded Mn/Zn-MOF with Enhanced Antioxidant Activities for Treating Atopic Dermatitis”为题进行分享，南方医科大学皮肤病医院范立民医师以“Mast cell -5-HT-HTR2A axis is involved in SADBE-induced chronic pruritus”为题作报告，首都医科大学附属北京中医医院高子钰医师以“Time-Dependent Characterization of MC903-Induced Atopic Dermatitis Mouse Models”为题进行交流，南昌大学第二附属医院寇彩霞医师以“Mechanism of Ion Channel Protein TMEM16A Inducing Skin Inflammation in Atopic Dermatitis via NF-κB Signaling Pathway”为题进行分享，上海市皮肤病医院李玎医师以“Environmental volatile organic compounds exacerbate atopic dermatitis via dendritic cell-specific CCR7 and CLEC7A dysregulation and convergent Staphylococcus aureus pathways”为题作报告。随后由宁夏医科大学总医院葛新红教授和中南大学湘雅二医院吴海竞教授继续主持。卡尔加里大学Vimal Hasmukh Prajapati医师以“Uncovering the high unmet need in AD: head and neck disease”为题进行交流，安徽医科大学第一附属医院刘学菲医师以“Decoding the “Barrier–Microbiota–Immunity” Network Driven by High-Salt Microenvironment in Atopic Dermatitis”为题进行分享，厦门大学药学院刘佑希医师以“MDI1228, a topical pan-JAK inhibitor, disrupts dermal fibroblast-T cell chemokine crosstalk to resolve allergic contact and atopic dermatitis”为题作报告，安徽医科大学第一附属医院龙小换医师以“IL-7/IL-7R Signaling Promotes the Pathogenesis of Atopic Dermatitis by Enhancing CD8⁺ T Cell Activation and Dendritic Cell Antigen Presentation”为题进行交流，浙江大学医学院附属第二医院毛莉雅医师以“Opsin 3 in keratinocytes mediates the light-induced exaggeration of atopic derma”为题进行分享，安徽医科大学第一附属医院彭博医师以“Differential CD4⁺ and CD8⁺ Cutaneous TRM Cell Responses in Murine Models of DNCB- versus MC903-Induced Atopic Dermatitis”为题作报告，西安交通大学第二附属医院秦淼医师以“Epidermal TET2 Deficiency Aggravates Atopic Dermatitis and Disrupts SPINK7 Expression Under Type 2 Inflammation”为题进行交流。本次专场展示了特应性皮炎发病机制与治疗研究领域的最新进展，现场学术氛围浓厚，为推动学术交流与临床转化提供了重要平台。 “适应性免疫与自身免疫、结缔组织病与自身免疫专场”在浙江省绍兴富悦温德姆酒店鉴湖1厅举行。本专场围绕皮肤免疫调控、自身免疫性疾病发病机制及潜在治疗靶点展开学术交流，涵盖斑秃、银屑病、系统性红斑狼疮、天疱疮、皮肌炎、系统性硬化症等疾病的基础研究与临床转化进展。 专场第一部分“适应性免疫与自身免疫”由厦门大学张凌娟教授和浙江大学医学院附属第二医院王亚琦教授共同主持。厦门大学张凌娟教授以“Dermal Fat: Mechanisms and Therapeutic Targets for Deep-Skin Anti-Inflammation and Anti-Aging”为题作报告，空军军医大学西京医院常毓倩教授以“CX3CR1 defines pathogenic CD8⁺ T cells and a targetable chemokine axis in alopecia areata”为题进行交流，浙江大学医学院附属第一医院陈怡然医师以“The Pathogenic Role of Dermal Neutrophil Infiltration in Systemic Lupus Erythematosus Progression”为题进行分享，四川大学华西医院冯迅医师以“From Antigen and Epitope Evidence to Real-World Immunophenotyping in Autoimmune Bullous Diseases”为题作报告，空军军医大学西京医院梁锦开医师以“High-Fat Diet–Induced Visceral Adipose Tissue Exosomes Promote Th17 Differentiation and Exacerbate Psoriasiform Inflammation via the Phosphatidylcholine–SREBP1–SCD1 Axis”为题进行交流，西安交通大学第二附属医院彭雪婷医师以“Repurposing Naloxone as an Anti-inflammatory Therapeutic Strategy for Pemphigus Vulgaris: Evidence from Human Skin Models and Passive Transfer Mouse Models”为题进行分享，安徽医科大学第二附属医院王峰医师以“Targeting IDO-1high Monocyte in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis”为题作报告，中国医学科学院皮肤病医院王来医师以“Blockade of ASCT2 Ameliorates Systemic Lupus Erythematosus by Suppressing CD4+ T Cell Expansion and T Follicular Helper Cell Generation”为题进行交流，安徽医科大学第一附属医院Yanmin Wang医师以“Unraveling the Role of mt-dsRNA in occupational medicamentose-like dermatitis due to trichloroethylene”为题进行分享，浙江大学医学院附属第二医院汤庄力医师以“Cell-free DNA profiles of dermatomyositis”为题作报告。 专场第二部分“结缔组织病与自身免疫”由浙江大学医学院附属第二医院汤庄力教授和周龙吟教授共同主持。上海交通大学医学院附属瑞金医院杨书缦医师以“The pathogenic role of peripheral helper T cells in pemphigus”为题进行交流，安徽医科大学第一附属医院杨小丽医师以“WTAP drives the inflammatory response and apoptosis in pemphigus vulgaris through IGF2BP2-mediated m6A modification of cGAS mRNA”为题进行分享，中南大学湘雅二医院杨志敏医师以“Retinoic acid promotes plasma cell differentiation and antibody responses through a B cell-intrinsic RARα–BLIMP-1 axis”为题作报告，贵州医科大学张财霞博士以“Study on the Mechanism of Blue Light-Induced Activation of Human Primary Langerhans Cells and the Expression Characteristics of Opsin 3”为题进行交流，昆明医科大学第二附属医院陈中宇医师以“Characteristics of Peripheral Blood CD8+ Effector Memory T Cells in Systemic Lupus Erythematosus Patients”为题进行分享，上海交通大学医学院附属瑞金医院邓映烨医师以“Cutaneous Manifestations of Sjögren Disease: Clinical Spectrum, Pathogenesis, and Therapeutic Perspectives”为题作报告，中南大学湘雅二医院李茜医师以“Molecular mechanism of AIM2 regulating B cell senescence and its role in the pathogenesis of systemic lupus erythematosus”为题进行交流，广州医科大学附属第二医院廖海琴医师以“Hydroxysafflor Yellow A Attenuates Skin Fibrosis in Systemic Sclerosis via Modulation of TGF-β/Smad3-Mediated M2 Macrophage Activation”为题进行分享，昆明医科大学第二附属医院浦芸静医师以“Granzyme K is a candidate biomarker of disease activity and B-cell dysregulation in systemic lupus erythematosus”为题作报告，上海交通大学医学院附属瑞金医院任儒风医师以“Clinical and immune stratification reveals divergent inflammatory patterns of pruritus in dermatomyositis: a single-center retrospective study”为题进行交流。 本次专场内容涵盖皮肤免疫稳态、T细胞与B细胞功能调控、中性粒细胞及单核细胞介导的炎症反应、自身免疫性皮肤病的分子机制与治疗靶点，以及疾病分层和生物标志物探索，集中呈现了该领域的多元研究方向，为促进皮肤免疫学基础研究与临床诊疗的交流融合提供了学术平台。 “色素性疾病与皮肤肿瘤专场”在浙江省绍兴富悦温德姆酒店鉴湖2厅举行。本专场围绕色素性皮肤病、皮肤肿瘤及相关临床转化进展展开交流，聚焦白癜风、黑色素瘤及其他色素性皮肤病，内容涵盖发病机制、肿瘤微环境、治疗耐药、遗传变异及临床疗效评价等方向。 专场第一部分由浙江大学医学院附属第二医院蔡绥勍教授和中南大学湘雅医院肖易教授共同主持。空军军医大学西京皮肤医院李舒丽教授以“From T Cell Pathogenesis to Precision Therapy: Redefining the Landscape of Vitiligo Treatment”为题作报告，浙江大学医学院附属第二医院陈加社医师以“CRKL amplification synergizes with mechanical stress-induced signaling to dually activate YAP oncogenic pathways, driving plantar melanoma progression”为题进行交流，南通大学附属医院崔晓美医师以“A novel fusion gene identified in metastatic melanoma associated with malignant transformation of a giant congenital melanocytic nevus”为题进行分享，深圳市慢性病防治中心胡绪乔医师以“Compositional analysis of extracellular vesicles-like particles from Acanthopanax senticosus and their inhibitory effects on SK-MEL-2 melanoma cells”为题作报告，宁波大学附属第一医院李燕君医师以“Cystinosin promotes melanoma development through ferroptosis via the GNMT/PARP1 pathway”为题进行交流，首都医科大学附属北京同仁医院吕淑淑医师以“Identification and Functional Analysis of Novel Pathogenic TYR Variants in Chinese Patients With Oculocutaneous Albinism Type 1B”为题进行分享，中国医科大学附属第一医院钱宣瑾医师以“ROS1 Upregulation Promotes Dabrafenib Resistance in Melanoma Cells Through Activation of RAF/ERK-Related Signaling Pathways”为题作报告，空军军医大学第二附属医院唐都医院王瑞娥医师以“Efficacy and Tolerability of 35% Glycolic Acid Peel for Melasma: A Split-Face Randomized Controlled Trial”为题进行交流，西安交通大学第二附属医院王熙医师以“Matrix stiffness reprograms mast cells into a pro-tumorigenic phenotype to drive melanoma progression”为题进行分享，空军军医大学第一附属医院许瑾媛医师以“MYC Amplification–Driven Replication Stress Confers Sensitivity to ATR Inhibition in Melanoma”为题作报告。 随后由昆明医科大学第一附属医院刘彤云教授和浙江大学医学院附属第二医院崔英哲教授继续主持。中南大学湘雅医院喻翩医师以“Azelnidipine Targets HER3 to Induce Cuproptosis and Overcome AKT Inhibitor Resistance in Melanoma”为题进行交流，南方医科大学第五附属医院周诗凤医师以“Serum Vitamin B12 and Malignant Melanoma: A Meta-Analysis and Systematic Review”为题进行分享，浙江大学医学院附属第一医院蔡晓萱医师以“Construction of Protein Conjugate PDL1-MT1 Based on Immune Checkpoint Activation and Its Effect on Vitiligo Repigmentation”为题作报告，北京大学第一医院太原医院杜晋芳医师以“Dynamic Microscopic Responses of Refractory Vitiligo Treated with 308nm Excimer Laser: The Value of Reflective Confocal Microscopy in Early Efficacy Evaluation”为题进行交流，江苏省人民医院冯奕菲医师以“Psychological stress induces vitiligo via the ROS/SAM-DNMT3A-CRABP1 metabolic-epigenetic axis”为题进行分享，空军军医大学第一附属医院贺楷乔医师以“The CDCP1–CD6 signaling axis regulates keratinocyte–T cell crosstalk to mediate the pathogenesis of vitiligo”为题作报告，宁夏医科大学总医院焦亚宁医师以“Application of Reflectance Confocal Microscopy in Clinical Management of Vitiligo: Staging and Early Therapeutic Monitoring”为题进行交流，西安交通大学第二附属医院李美萱医师以“Efficacy and Safety of Cold Atmospheric Plasma–Activated Hydrogel for Early Localized Vitiligo: A Multicenter Randomized Controlled Trial”为题进行分享，安徽医科大学第一附属医院李德意医师以“Analysis of Caffeine and Its Metabolites in Urine of Patients with Non-Segmental Vitiligo Based on UPLC-MS/MS Targeted Metabolomics”为题作报告。 本次专场集中展示了白癜风、黑色素瘤等色素性皮肤病在发病机制、肿瘤微环境、治疗耐药及临床疗效评价等方向的最新研究进展，为皮肤病学基础研究、临床诊疗与转化应用的交流融合提供了重要平台。 本次10月16日上午场6个分会场内容涵盖银屑病、特应性皮炎、色素性皮肤病、皮肤自身免疫性疾病、皮肤基因组与表皮屏障及毛发疾病等多个方向，兼顾基础研究深度与临床转化广度，充分展示了皮肤科学领域的最新研究成果与前沿探索，为推动学术交流与临床转化提供了重要平台。 下午场共设6个分会场，分别聚焦皮肤肿瘤、炎症性皮肤病、皮肤衰老与人工智能、特应性皮炎与微生物感染、银屑病发病机制与精准治疗、结缔组织病与皮肤组学、毛发与自身免疫及皮肤再生、色素性疾病与皮肤肿瘤基因组学等方向。来自全国多家医疗机构及高等院校的专家学者围绕前沿进展与临床转化展开深入交流。 “Late-Breaking Research, AI and General Dermatology”专场在绍兴富悦温德姆酒店富悦3厅顺利举行。本专场聚焦皮肤肿瘤、炎症性皮肤病、皮肤衰老及人工智能赋能皮肤病研究等前沿方向，围绕皮肤疾病的前沿进展与临床实践展开深入交流。 专场第一部分由复旦大学附属华东医院王宏伟教授和浙江大学医学院附属第二医院陈钰虹教授共同主持，北京大学第一医院汪肠教授以“Malignant Transformation of T cells in Cutaneous T Cell Lymphoma”为题进行分享，山东大学齐鲁医院李颖教授以“Preliminary Study on Ocular Comorbidities of Atopic Dermatitis”为题作报告，北京大学第三医院徐琳琳医师以“UBE2M-Regulated Endosomal IgG Sorting Mitigates Hair Follicle Aging”为题进行分享，中国医学科学院皮肤病医院（中国医学科学院皮肤病研究所）高长醒医师以“A rapamycin-adjuvanted chromatin-based therapeutic vaccine for systemic lupus erythematosus”为题作报告，上海市皮肤病医院姜晓文医师以“Idebenone and TRP-2 mRNA Lipid Nanoparticles Enhance Dendritic-Cell Activation and Anti-tumor Immunity in Melanoma”为题进行交流，宁波大学刘力伟医师以“Dual-Hit Disruption of Autophagic Flux by the Marine-Derived Cyclopeptide Turnagainolide B Selectively Kills Melanoma Cells and Suppresses Tumorigenesis In Vivo”为题发言。 专场第二部分由浙江大学医学院附属第二医院劳力民教授和浙江大学医学院附属第二医院李伟教授共同主持，中国人民解放军空军军医大学第一附属医院张晨医师以“A Nutrient-Sensitive O-GlcNAc Switch on RIPK1 Controls Necroptosis and Tissue Homeostasis”为题进行分享，重庆医科大学附属第一医院姜子琪医师以“CD4+ Tissue-Resident Memory T Cells Drive Acne Recurrence and Progression”为题作报告，复旦大学附属华山医院韦依宁医师以“Reduced endothelial CD36 expression promotes a TGM2high endothelial state and fibroblast activation in keloids”为题作报告，复旦大学附属华东医院陈千一医师以“Apelin Receptor can Act as a Specific Marker and Promising Therapeutic Target for Infantile Hemangioma”为题进行交流，中南大学湘雅二医院陈凯丽医师以“Artificial Intelligence Integrates Multi-omics to Screen Molecular Subtypes and Prognostic Markers of Systemic Lupus Erythematosus”为题作报告，南方医科大学南方医院黄云帆医师以“Expression Characteristics and Preliminary Mechanism of the TAP2-CD8+ Effector Memory T Cell Axis in PD-1 Inhibitor-Induced Cutaneous Immune-Related Adverse Events”为题进行交流，上海市第一人民医院王之凯医师以“Skin-innervating glutamatergic neurons modulate aging”为题发言。本次专场展示了皮肤科领域最新研究成果与前沿探索，为推动学术交流与临床转化提供了重要平台。 “特应性皮炎、微生物感染与转化研究”专题学术交流在浙江绍兴富悦温德姆酒店富悦5厅顺利举行。本专场聚焦特应性皮炎发病机制、微生物感染、神经免疫调控、免疫代谢及创新治疗策略等研究热点，分为两个场次展开深入交流。 专场第一部分由安徽医科大学第一附属医院王再兴教授和浙江大学医学院附属第二医院陈学嫣医师共同主持，山东第一医科大学附属皮肤病医院糜自豪教授以“The mechanism of innate immune tolerance induced by the MDP-NOD2-ACOD1 axis in macrophages”为题作报告，重庆医科大学附属第一医院贺文艳教授以“Single-cell analysis identifies a type 2 immune-stromal remodeling circuit in primary cutaneous amyloidosis”为题作报告，复旦大学附属华山医院应佳联医师以“A dual-locked fluorescent probe for imaging of human primary melanocytes and melanoma tissues via tyrosinase and hydrogen sulfide activation”为题进行交流，中国医学科学院皮肤病医院张煜涵医师以“Gut Translocated Pathobiont Contributes to Lupus Nephritis and Renal Fibrosis via Gut-Kidney Axis”为题作报告，南方医科大学南方医院黄缨婷医师围绕“Role of RBT5 in Candida albicans Biofilm Drug Resistance and Targeted Therapeutic Strategies”进行交流，厦门大学药学院李洁博士以“Dermal Adipocyte-Macrophage Crosstalk Fuels a Feed-Forward Circuit of Inflammation and Fibrosis in Atopic Dermatitis”为题作报告。 专场第二部分由同济大学附属皮肤病医院郭春源研究员和华东师范大学赖玉平教授共同主持，天津医科大学总医院罗大双医师以“Mechanism Study of Epigenetically Mediated ALDH3A1 Downregulation Regulating 4-HNE-GPX4 Axis Involved in Chlamydia trachomatis-Induced Host Ferroptosis”为题作报告，中南大学湘雅医院马斯慧医师以“Dual-Functional Boron-Doped Copper Single-Atom Nanomaterial for Targeted Disruption of the TSLP Axis in Atopic Dermatitis”为题作报告，浙江大学医学院附属第二医院李芳医师以“Aging-associated HILPDA+ macrophages fuel inflammation and metabolic dysfunction of atopic dermatitis”为题进行交流，西安交通大学第二附属医院易梦瑶医师以“Cold Exposure Exacerbates Atopic Dermatitis through a TRPA1-SREBP1-Unsaturated Fatty Acid Metabolic Reprogramming Axis”为题作报告，浙江大学医学院附属第一医院文海煜医师以“Sensory neuron-derived Neuromedin B drives pruritus and type 2 skin inflammation in Atopic Dermatitis”为题发言，中南大学湘雅医院张汉伊医师以“Emotional distress aggravates atopic dermatitis through IFNγ-PD-L1⁺ neutrophil axis”为题进行交流，华中科技大学同济医学院附属同济医院王翌菲医师以“Linoleic Acid Reinforces a CD36-High Regulatory Langerhans Cell Program to Ameliorate Atopic Dermatitis-like Inflammation”为题进行交流，浙江大学医学院附属第二医院张美洁医师以“Mmp12+ Macrophage Subset in Cutaneous Mucor irregularis Infection”为题作报告。本次专场展示了特应性皮炎、微生物感染与转化研究领域的最新进展，为推动学术交流与临床转化提供了重要平台。 “银屑病：发病机制与精准治疗”Session1及Session2专场在分会场3-三层群贤1厅顺利举行。本专场聚焦银屑病发病机制与精准治疗，围绕遗传易感、免疫代谢、神经免疫环境因素及生物制剂应答等方向展开深入交流。 专场第一部分由上海市皮肤病医院史玉玲教授和天津医科大学总医院王惠平教授共同主持，北京大学第三医院梁晓丰医师围绕“Twice-Daily Induction Followed by Twice-Weekly Proactive Maintenance with Benvitimod Reveals Stage-Specific Molecular Remodeling in Psoriasis Inflammation: Downregulation of Neutrophil-Associated Molecules and Enhanced Keratinocyte Differentiation”进行分享，重庆医科大学附属第一医院彭或婷医师在“Rare TIGIT variants implicate impaired Treg/Th17 regulation in psoriasis: evidence from population-scale exome sequencing and functional validation”中作交流，同院王萍医师分享了“Discovery of serum proteomic signature in different sub-types of psoriasis patients based on data-independent acquisition mass spectrometry”，复旦大学附属华山医院董灿彬医师就“Fibroblast-derived MMP2 drives tissue-resident memory T cell formation via TGF-β1 activation and remodels the immune microenvironment in psoriasis”作报告，空军军医大学西京皮肤医院周一帆医师以“NNMT-dependent fibroblast metabolic memory sustains tissue-resident memory T cell niches in recurrent skin inflammation”为题发言，上海市皮肤病医院杨楠医师带来“Bacteria-Derived Tyramine Restrains CD8⁺ Tissue-Resident Memory T Cells to Limit Recurrent Skin Inflammation”的报告，同院邓思会医师围绕“The Role and Mechanism of Langerhans Cells in Psoriasis Recurrence”进行交流。 专场第二部分由浙江大学医学院附属第一医院乔建军教授和浙江大学医学院附属第二医院王昭圆医师共同主持，复旦大学附属华山医院董灿彬医师以“Anxiety-Driven Sympathetic Activation Compromises Psoriasis Therapy via the ADRA2A-CCL2-CCR2+ Monocyte Axis”为题作报告，厦门大学林晟医师在“Beyond energy storage: Dermal adipocytes reprogram macrophages to fight against psoriatic Inflammation”中分享，上海交通大学医学院附属瑞金医院张莉医师就“Reduced CYP1A1 Is Associated with Residual Psoriatic Lesions During Anti-IL-17A Therapy”发言，上海市皮肤病医院黄越萌医师以“IL-17A Drives DNMT1-Dependent Epigenetic Reprogramming in Keratinocytes During Psoriatic Inflammation”为题交流，华中科技大学同济医学院附属协和医院张心悦医师围绕“Ambient NO₂ promotes psoriasis-like skin inflammation by regulating keratinocyte-derived chemotaxis CXCL2”发言，上海市皮肤病医院张亦真医师就“PLA2G4B promotes psoriatic inflammation through arachidonic acid metabolic dysregulation and lipid peroxidation in keratinocytes”作报告，浙江大学医学院附属第二医院陈希贝医师在“Plasma proteomic patterns associated with sustained clinical response to guselkumab in plaque psoriasis”中交流。本次专场展示了银屑病多维度机制研究和精准治疗新进展，为推动学术交流与临床转化提供了重要平台。 “Psoriasis, Connective Tissue Diseases and Skin Omics Session”专场于三层群贤厅2隆重举行，紧扣银屑病、特应性皮炎、天疱疮、皮肤红斑狼疮等免疫性皮肤病，以及多组学、空间转录组、免疫代谢、环境与节律等热点方向展开交流。 本场会议特邀第四军医大学西京医院邵帅教授和浙江大学医学院附属第二医院徐凡教授共同担任主持。中国医学科学院皮肤病医院樊欣雨教授以“Circadian-Misaligned Fasting Is Associated with Human Immunosenescence and Exacerbates Psoriasiform Inflammation in Mice”为题作报告；中南大学湘雅医院蒋骞教授以“Vitamin D-DDIT4-PHBs axis reprograms CD4⁺ T cell metabolism to restrain autoimmunity”为题作报告；上海市皮肤病医院陈泽毓医师以“Complement C3 links fibroblasts to IL-17-driven inflammation in psoriasis”为题作报告；上海市皮肤病医院蔡江鲁伊医师以“PPARγ Maintains Th17 Immunometabolic Homeostasis through the CPT1A-Carnitine Axis in Obesity-Associated Psoriasis”为题作报告；宁波大学李颖曦医师以“Keratinocyte-derived ligand-receptor axis orchestrates neutrophil phenotypes during psoriasis”为题作报告；上海市皮肤病医院陈茜宇医师以“IL-6 Primes Keratinocytes for Enhanced Inflammatory Responses via FOS-dependent Chromatin Remodeling”为题作报告；中南大学湘雅三医院裴诗谣医师以“Multi-Omics Integrated Analysis Reveals the Efficacy and Outcome Mechanisms of Acidified Aliphatic Ester in Atopic Dermatitis”为题作报告；浙江大学医学院附属第二医院芦怡医师以“Spatiotemporal Dynamics of Tregs in Psoriasis”为题作报告。 随后由北京大学第一医院汪旸教授和首都医科大学附属北京朝阳医院何焱玲教授继续主持。华中科技大学同济医学院附属协和医院陶娟教授以“Air pollution and psoriasis”为题作报告；安徽医科大学第一附属医院张悦康医师以“Integrative Whole-Genome and Single-Cell RNA Sequencing Identify CDCA7 and RUBCNL as Contributors to Pemphigus Vulgaris Risk”为题作报告；陆军军医大学第一附属医院（西南医院）陈静医师以“Integrated proteomic and metabolomic profiling of a psoriasis-atopic dermatitis overlap cohort reveals neutrophilic inflammation and sphingolipid metabolic reprogramming”为题作报告；浙江大学医学院附属第二医院吕铭悦医师以“Exploring the role of pathogenic CD5t T Cels in psoriasis and the thera”为题作报告；上海交通大学医学院附属瑞金医院何开乐医师以“Decoding the shared genetic basis of dermatomyositis and interstitial lung disease: multi-omic insights and novel therapeutic targets”为题作报告；上海交通大学医学院附属瑞金医院柯慧怡医师以“High-Resolution Spatial Transcriptomics Maps Compartmentalized Cell Organization and Distinct Immune Niche Remodeling in Pemphigus Lesional Microenvironment”为题作报告；浙江大学医学院附属第一医院胡芝医师以“Estrogen-ERα/MEDAG Signaling Drives Pro-inflammatory Fibroblast Differentiation in Cutaneous Lupus”为题作报告；浙江大学医学院附属第二医院陈钰虹医师以“The MEG3/miR-21-5p/PTEN Axis Regulates Hair Follicle Cycle Progression by Modulating Outer Root Sheath Cell Function”为题作报告。本次论坛集结了众多领域内权威专家，报告立意高远、内容丰实，既深入剖析基础研究，又前瞻展望临床转化，为皮肤学科高质量发展增添了新动力。 “Hair, Autoimmunity and Skin Regeneration Session 1与Session 2”在浙江省绍兴富悦温德姆酒店鉴湖1厅顺利举行。会议聚焦毛发疾病、自身免疫性皮肤病与皮肤再生等领域，来自全国多家医院的教授围绕各自研究进行了报告。 专场第一部分由浙江大学医学院附属第一医院方红教授和浙江大学医学院附属邵逸夫医院程浩教授共同主持。大连医科大学附属第二医院周雯慧医师以“Spatial Characterization Reveals Stress Keratinocytes Drive Acute Cutaneous Lupus Erythematosus Lesion Pathogenesis via the IFN-γ-JAK-STAT-CXCL9/10/11 Axis”为题作报告；贵州医科大学附属医院杨梦兰医师以“Blue Light Dose-Dependently Triggers Spatial Disorganization of Stratified Architectire in Melanocyte-Keratinocyte 3D Microclusters”为题作报告；桂林医科大学第一附属医院彭世雄医师以“KRT6A derived from mesenchymal stem cells as a potential biomarker and therapeutic target for alopecia areata: insights from multi-omics analysis and experimental evidence”为题作报告；昆明医科大学第二附属医院朱庆焕医师以“Investigating the Role and Mechanisms of B Cell Dysfunction in SLE Pathogenesis via the Ferroptosis-Related Gene DDIT3”为题作报告；南方医科大学南方医院郑思齐医师以“Mechanism of Inhaled Aromatherapy in Alleviating Rosacea through the PI3K-Akt-Galanin Signaling Axis”为题作报告；南方医科大学南方医院刘玉洋医师以“Targeting IFN-γ-JAK-STAT-PD-L1 Signaling Restores Hair Follicle Immune Homeostasis in Alopecia Areata”为题作报告；南方医科大学皮肤病医院陈俊溢医师以“Endoplasmic reticulum stress upregulates mesenchymal fibroblasts in keloids by activating the CREB3L1-XBP1s axis.”为题作报告；第四军医大学附属西京医院王冰医师以“Rituximab Depletes Antigen-Responsive CD20+ T Cells with T Follicular Helper-like Features in Pemphigus Vulgaris”为题作报告。 专场第二部分由南通大学附属医院陈晓栋教授和南方医科大学南方医院郑跃教授共同主持。浙江大学医学院附属第二医院毛美淇医师以“HSPA2 ubiquitination by IFN-γ/AKT/mTOR signaling suppresses hair follicle cell proliferation in alopecia areata”为题作报告；山东第一医科大学谢玮医师以“Desmosome-microtubule coupling by ENKD1 sustains epithelial resilience against autoantibody-mediated injury”为题作报告；山东第一医科大学附属皮肤病医院孙乐乐医师以“TSC22D3 in NK cells converts infection from protective to lethal drug hypersensitivity via GZMB and CCL5”为题作报告；四川省医学科学院四川省人民医院赵灵运医师以“Xeno-free Generation of Induced Hair Follicle Stem Cells and Their Therapeutic Mechanism for Androgenetic Alopecia”为题作报告；中国科学技术大学附属第一医院陈琪医师以“PTN-SDC1 Axis-Mediated Dysregulation of Infundibular Epithelial-Langerhans Cell Crosstalk in Female Pattern Hair Loss”为题作报告；中国医科大学附属盛京医院程铭医师以“miR-574-3p and miR-125a-5p in Adipose-Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/SMAD2 Signaling Pathway for the Treatment of Androgenic Alopecia”为题作报告；浙江大学医学院附属第二医院苗宇杰医师以“Transcriptomic and Proteomic Profiling of the Local Immune Microenvironment in Alopecia Areata”为题作报告。本次“毛发、自身免疫与皮肤再生 Session 1”与“Session 2”共安排16场Rising Star报告，覆盖急性皮肤型红斑狼疮、斑秃、玫瑰痤疮、瘢痕疙瘩、天疱疮、药物超敏反应、雄激素性脱发、女性型脱发等研究方向。 “色素性疾病、皮肤肿瘤与基因组学专场”在浙江省绍兴富悦温德姆酒店鉴湖2厅举行。本专场围绕色素性皮肤病、皮肤肿瘤及基因组学相关基础研究与临床转化进展展开交流，内容涵盖皮肤T细胞淋巴瘤、黑色素瘤、白癜风、皮肤光老化及遗传性表皮分化异常等疾病的分子机制、免疫微环境和潜在治疗靶点。 专场第一部分“色素性疾病、皮肤肿瘤与基因组学Session1”由昆明医科大学第二附属医院邓丹琪教授和郑州大学第一附属医院李旭阳教授共同主持。北京大学第三医院何啸教授以“CISD1 suppression by miR-320a drives ferroptosis in CTCL by disrupting mitochondrial dynamics to activate the cGAS/STING pathway”为题进行分享；南方医科大学南方医院彭梦然教授以“Therapeutic Effect and Safety of Functional Migrasomes on Dermal Microvascular Atrophy in Skin Photoaging”为题作报告；南方医科大学皮肤病医院张泽乔医师以“Biallelic GLTP mutations cause nonsyndromic epidermal differentiation disorder via disrupted epidermal glucosylceramide transport”为题介绍研究进展；山东第一医科大学附属皮肤病医院李文超医师以“Deciphering the shared genetic architecture of gut-brain-skin comorbidity through genome-wide cross-trait and multi-omics analyses”为题进行汇报；上海交通大学医学院附属上海儿童医学中心宋丽娜医师以“Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Abnormal Intercellular Communication in the Malignant Progression of Pediatric Giant Congenital Melanocytic Nevi”为题分享研究成果；首都医科大学附属北京友谊医院尚琳医师以“TREM2+ Macrophage-Fibroblast Crosstalk and LRG1 Mediate PLLA-b-PEG/HA-Induced Skin Photoaging Repair”为题作学术交流；西南医科大学附属医院毛汉潇医师以“Interleukin-7-induced melanocytes autophagy elevates MHC class I expression via PI3K/AKT/mTOR pathway and contributes to melanocyte loss in vitiligo”为题介绍有关研究。 专场第二部分“色素性疾病、皮肤肿瘤与基因组学 Session 2”由宁夏医科大学总医院葛新红教授和空军军医大学西京皮肤医院李舒丽教授共同主持。新疆维吾尔自治区人民医院王云颖医师以“Single-Cell Functional Atlas of the Kaposi's Sarcoma Microenvironment Reveals Global CAF Activation, IFN-Primed Macrophages, and Vessel-Wall Immune Reprogramming”为题作报告；浙江大学医学院附属第一医院姜怡医师以“Beyond CD30: Dual-Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides”为题介绍研究进展；郑州大学第一附属医院李旭阳医师以“Temporal Characteristics of Photodynamic Therapy in Remodeling Local Immune Microenvironment and the Potential HSPA1A/HSPA6 Regulatory Network in Condyloma Acuminatum”为题进行汇报；中国医科大学附属盛京医院丛天昕医师以“Quercetin Protects against MBEH-Induced Melanocyte Injury by Suppressing Pyroptosis and Alleviating Oxidative Stress”为题分享研究成果；中山大学孙逸仙纪念医院郭书萌医师以“Statins targeting the mevalonate-KLF2 axis suppress cutaneous T-cell lymphoma and synergize with bexarotene”为题作学术交流；空军军医大学西京皮肤医院黄露玲医师以“Sympathetic Nerve Aggravates Vitiligo via NE-Adrenergic Receptor Axis: Mechanistic Insights Into Cutaneous Neuroimmune Crosstalk”为题介绍有关研究；西京医院孙宁玥医师以“Targeting MITF Sensitizes Melanoma to Therapy by Enhancing Pyroptosis”为题进行分享；空军军医大学第一附属医院郭伟楠医师以“TREM2+ macrophages license CD8+ T-cell cytotoxicity through choline metabolism in vitiligo”为题作报告；中国医科大学附属第一医院王馨悦医师以“Ca2+-Dependent PLD2-PA-Rac2 Signaling Mediates Electric Field-Induced Enhancement of Dendritic Cell Antigen Presentation in Melanoma Immunotherapy”为题介绍研究进展。本次专场集中展示了皮肤肿瘤分子机制、黑色素细胞损伤与白癜风神经免疫调控、皮肤免疫微环境重塑、遗传学与多组学研究、光老化修复以及新型治疗策略等方向的研究进展，为皮肤病学基础研究、临床诊疗与转化应用的交流融合提供了重要平台。 本次10月16日下午场6个分会场内容涵盖皮肤肿瘤、炎症性皮肤病、自身免疫性疾病、银屑病、特应性皮炎、毛发疾病、色素性疾病、皮肤衰老及人工智能与多组学交叉应用等多个方向，兼顾基础研究深度与临床转化广度，充分展示了皮肤科学领域的最新研究成果与前沿探索，为推动学术交流与临床转化提供了重要平台。 排版 | 隐逸