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更新于：2026-09-24
Polyvinyl alcohol
聚乙烯醇
更新于：2026-09-24
概要
基本信息
原研机构- |
在研机构 |
非在研机构- |
权益机构- |
最高研发阶段批准上市 |
首次获批日期 中国 (1999-01-01), |
最高研发阶段(中国)批准上市 |
特殊审评- |
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结构/序列
分子式C2H4O |
InChIKeyIMROMDMJAWUWLK-UHFFFAOYSA-N |
CAS号9002-89-5 |
关联
4
项与 聚乙烯醇 相关的临床试验ITMCTR2026001055
The Clinical Efficacy of Polyvinyl Alcohol Eye Drops Combined with Acupuncture in the Treatment of Dry Eye Syndrome
NCT05490381
Super-Selective Intra-Arterial Embolization of Hypervascular Head and Neck Tumors
ChiCTR2400088959
Prospective, multicenter, randomized controlled trial to validate the safety and efficacy of polyvinyl alcohol embolization microspheres for transarterial chemoembolization of liver cancer
100 项与 聚乙烯醇 相关的临床结果
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100 项与 聚乙烯醇 相关的转化医学
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100 项与 聚乙烯醇 相关的专利（医药）
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1,418
项与 聚乙烯醇 相关的文献（医药）2026-10-01FOOD CHEMISTRY
Zn2+-enhanced dual-mode intelligent film based on natural polysaccharides and quercetin for real-time visual monitoring of shrimp freshness
Article
作者: Wu, Gang ; Su, Wei ; Wu, Guangyu ; Huo, Lini ; Li, Peiyuan ; Zhong, Haiyi
This study innovatively employs Zn2+ as a dual-functional enhancer to address the weak signal and single response of flavonoid-based smart packaging. A multifunctional film, SCP/QR/Zn2+(SCP represents sodium alginate/carboxymethyl cellulose/polyvinyl alcohol and QR denotes quercetin), was fabricated via a one-pot method. Zn2+ significantly improved tensile strength (19.18 MPa), elongation (73.68%), water resistance (23.73% solubility), and antibacterial activity. Crucially, Zn2+ coordination synergistically enhanced the film's dual-mode (colorimetric/fluorescent) response to pH/ammonia, improving reliability over single-mode systems. The film exhibited a rapid, reversible response to ammonia with a 4.87 ppm detection limit. Color/fluorescence changes highly correlated (R2 > 0.98) with shrimp TVB-N, providing a clear visual spoilage alert beyond the safety threshold (25 mg/100 g). This work offers an effective strategy to overcome natural indicators' limitations, creating a high-performance, multifunctional active packaging system.
2026-09-01INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Fabrication of sustainable sodium alginate-based building thermal insulation composite aerogel with robust self-healing and repeatable fire warning performance
Article
作者: Zheng, Qiaohong ; Ji, Changchun ; Wang, Yudong ; Yu, Zhicai
The construction of building insulation materials with high fire safety and sustainable development has become a hot research topic and urgent need in the field of architecture. However, traditional building insulation materials have the problems of flammability, inability to actively fire warning and lack of sustainable materials. Herein, polyvinyl alcohol/sodium alginate/Ag2Se (PSA) composite aerogels exhibiting flame retardancy, fire warning capabilities, and self-healing properties were synthesized using a double cross-linking network and a freeze-thaw cycle strategy. The synergistic effect of boric acid and Ag2Se nanoparticles significantly improved the flame retardancy of PSA aerogels. The peak heat release rate decreased by 18.2%, and the total heat release rate decreased by 41.1%. Utilizing a low thermal conductivity of less than 0.08 W·m-1·K-1, a stable temperature differential is established between the hot and cold ends. Through the thermoelectric effect of Ag2Se, a fast self-powered fire alarm within 3 s after contacting the flame is realized. Both of them improved the fire safety of PSA aerogels. Based on the natural polysaccharide sodium alginate as the matrix, the dynamic borate ester bond reconstruction is triggered by water to achieve 2 min of rapid self-healing without losing the self-powered fire warning function, which has the sustainable advantages of environmental friendliness and high durability. PSA aerogel provides an intelligent and collaborative solution for building thermal insulation materials with high fire safety and sustainable development through reversible fire warning and robust self-healing performance, which significantly promotes its practical application in the construction field.
2026-08-01INTERNATIONAL JOURNAL OF PHARMACEUTICS
Transient hydrate formation during disintegration of film-coated pharmaceutical tablets
Article
作者: Zeitler, J Axel ; Powell, Daniel ; Nassar, Marwa ; Ma, Mingrui ; Teckoe, Jason ; Markl, Daniel ; Zeng, Xiaorui
The transformation of anhydrous tablet excipients into their hydrated forms occurs simultaneously with film coating dissolution, yet the kinetics of this process remain poorly understood. Water molecules diffuse through the immediate release film coating and form hydrogen bonds with the anhydrous components within the tablet core, creating a thermodynamic driving force that competes with the hydration of the coating polymer. This study investigates the influence of film coating properties, including the base polymer (polyvinyl alcohol versus hydroxypropyl methylcellulose), coating thickness, and coating density, alongside tablet core properties such as porosity and excipient type. Using polymer-coated tablets containing anhydrous lactose or magnesium sulphate, we demonstrate that terahertz pulsed imaging (TPI) captures this diffusion process non-destructively. We characterise the anhydrous-to-hydrate transformation based on subtle refractive index changes at the interface. We identify distinct hydration mechanisms for channel hydrates versus ion-coordinated hydrates, providing further evidence that the core formulation actively regulates water ingress prior to coating failure. These findings offer critical insights for the predictive modelling of film-coated tablet disintegration and dissolution.
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| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 干眼症 | 中国 | 1999-01-01 |
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