The objective of this clinical trial is to assess the effectiveness of acetic acid in patients suffering from chronic cutaneous ulcers with biofilm. The primary question it seeks to address is whether acetic acid (as a 2% topical solution) is superior to the current standard treatment for chronic cutaneous ulcers with biofilm at our center (Prontosan®).
Participants will be randomly assigned to receive either the acetic acid solution treatment or the standard current treatment.

开始日期2024-09-01

申办/合作机构-

IRCT20240804062634N1

/ Recruiting临床2期IIT

Investigating the effect of herbal shampoo containing Gharaghorot, vinegar and ajwain on head lice: a clinical trial study

开始日期2024-08-22

申办/合作机构-

NCT06525870

/ Enrolling by invitation临床2期IIT

Efficacy of Topical 85%Trichloroacetic Acid in the Treatment of Low-grade Squamous Intraepithelial Lesion (LSIL) After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial

To determine the efficacy and HPV clearance of an application of 85% TCA compared to placebo in the treatment of LSIL. This is a randomized, single-blind, placebo-controlled study in 44 women aged 18-65 years with histologic-proved HPV/CIN1. The study will test whether 85% TCA application will be effective treatment in LSIL. The clinical study hypothesis is that TCA application at cervical lesion and transformation zone will achieve histologic complete remission of LSIL in significantly more patients than placebo therapy. Patients will be randomized to placebo (3% acetic acid) or 85%TCA topical application at cervical lesion and transformation zone. After 3 months, cytology, colposcopy, histology, and HPV testing will be performed. The primary endpoint is treatment efficacy defined as complete histologic remission at 3 months after treatment. The secondary endpoint is HPV clearance 3 months after treatment. The protocol for the project is approved by an Institutional Review Board (IRB). Project is totally supported by a grant from Rajavithi Hospital. There is no external funding.

开始日期2024-08-01

申办/合作机构

Rajavithi Hospital

100 项与酢酸相关的临床结果

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100 项与酢酸相关的转化医学

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100 项与酢酸相关的专利（医药）

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项与酢酸相关的文献（医药）

2025-02-01·CHEMOSPHERE

Comprehensive evaluation of sodium dichloroisocyanurate (NaDCC) tablets as a novel solid-state alternative to conventional membrane cleaning agents in gravity-driven filtration systems

Article

作者: Yoon, Yeomin ; Choi, June-Seok ; Rho, Hojung ; Jung, Hyejin ; Jun, Byung-Moon ; Lee, Jonghun

Gravity-driven membrane (GDM) systems are increasingly recognized as sustainable and energy-efficient solutions for decentralized water treatment. However, membrane fouling, particularly by organic matter, remains a significant operational challenge, necessitating regular chemical cleaning to maintain performance. The present study was undertaken to investigate the cleaning efficiency of sodium dichloroisocyanurate (NaDCC) tablets, a novel solid-state alternative to conventional liquid cleaning agents such as sodium hypochlorite (NaOCl), sodium lauryl sulfate (SLS), acetic acid, and citric acid. NaDCC tablets, originally developed for drinking water disinfection, offer advantages in terms of transport, storage, and safety compared with conventional liquid formulations. A comparative evaluation of cleaning agents was conducted on hollow fiber membranes used in GDM systems, with the concentration and contact times optimized for each chemical. NaOCl demonstrated the highest permeability recovery, reaching 48.29% at 500 mg L^-1 after 12 h, followed closely by NaDCC, with a recovery of 46.55% under similar conditions. Conversely, SLS, acetic acid, and citric acid presented significantly lower recovery rates, with maximum flux restorations of 14.57%, 14.90%, and 16.73%, respectively. These results highlight the comparable performance of NaDCC and NaOCl in addressing organic fouling while offering practical advantages such as greater stability and reduced chemical handling risks. This study highlights the efficacy of NaDCC as a viable detergent for GDM systems, and also provides a comprehensive comparative analysis of the water permeability performances of commercial detergents such as NaOCl, which cause various ecotoxicities, and suggests the feasibility of NaDCC as a chemical detergent in practical membrane processes. Our findings contribute to the development of more sustainable and cost-effective membrane-cleaning protocols that enhance long-term operational efficiency and minimize environmental impacts.

2025-01-01·Biomaterials advances

Simultaneous viscoelasticity and sprayability in antimicrobial acetic acid-alginate fluid gels

Article

作者: Robinson, Thomas E. ; Schofield, Zoe ; Geoghegan, Joan A. ; Grover, Liam M. ; Moakes, Richard J A ; Robinson, Thomas E ; Clark, Callum ; Grover, Liam M ; Geoghegan, Joan A ; Moiemen, Naiem ; Moakes, Richard J.A.

Acetic acid is a promising alternative to antibiotics for topical applications, particularly burn wounds, however its site specificity and retention are impaired by poor material properties. In this study, acetic acid was investigated as both the gelling agent and antimicrobial active in alginate fluid gels. The formed microstructure was found to be directly dependent on acetic acid concentration, leading to highly tuneable material properties. At clinically relevant concentrations of 2.5-5 % acetic acid, the fluid gels were elastically dominated at rest, with viscosities up to 7 orders of magnitude greater than acetic acid alone. These material properties imparted long term surface retention and microparticle barrier function, not seen with either acetic acid or alginate solutions. Most notably, sprayability was enhanced simultaneously with the increased viscosity and elasticity due to the introduction of a discretised microstructure, leading to a remarkable tenfold increase in spray coverage. Formulation was found not to inhibit antimicrobial activity, despite the less acidic pH, with common burn wound pathogens Staphylococcus aureus and Pseudomonas aeruginosa being equally susceptible to the fluid gels as to acetic acid solutions.

2025-01-01·FOOD RESEARCH INTERNATIONAL

Euglena gracilis polysaccharide modulated gut dysbiosis of obese individuals via acetic acid in an in vitro fermentation model

Article

作者: Guo, Bingbing ; Liu, Bin ; Zou, Jingwen ; Zhang, Weihao ; Dong, Ningning ; Zhang, Jingyi

Gut dysbiosis is a characteristic feature of obesity and targeting gut microbiota presents a promising approach to attenuate obesity. Euglena gracilis polysaccharide (EGP) has emerged as a potential prebiotic capable of promoting health-beneficial bacteria. However, its effects on the gut dysbiosis of obese individuals remain unclear. This study investigated the impacts of EGP on gut microbiota from both non-obese and obese individuals using an in vitro fermentation model. Results showed that EGP significantly altered the gut microbiota composition and metabolism. Specifically, EGP improved the relative abundance of Paeniclostridium, Clostridium_sensu_stricto_1 and Paraclostridium of the non-obese individuals and Providencia, Enterococcus and Bacteroides of the obese individuals. Metabolomics results showed EGP significantly altered the lipid metabolism especially in the obese group with enriched bile secretion and cholesterol metabolism pathways. Noting that acetic acid was significantly increased in both groups, these acetic acid favorable microbiota from non-obese individuals was collected with acetic acid supplementation. Transplantation of these acetic acid-induced microbiota (AAiM) notably improved the richness and diversity of fecal microbiota of the obese individuals, enhancing the growth of probiotics like Bacteroides and Bifidobacterium. Consequently, AAiM significantly restructured macronutrients (including amino acids, carbohydrates and lipids) metabolism of the gut microbiota from obese individuals. Altogether, this study underscores the potential of EGP and acetic acid favorable microbiota in manipulating obesity-associated gut dysbiosis via acetic acid production.

项与酢酸相关的新闻（医药）

2024-12-13

·生物世界

PLOS Biology：戴磊/陈沫先团队揭示植物根际微生物对生长素的分解代谢

编辑丨王多鱼排版丨水成文生长素（auxins）是植物体内一类重要的激素，广泛参与调控植物的生长、发育及应答外部环境的变化。生长素的研究始于19世纪末，是最早被发现的植物激素之一。作为主要的天然生长素分子，吲哚-3-乙酸（IAA）在植物中含量最为丰富，并在植物的多个发育过程中发挥关键作用，包括细胞分裂、根系发育、细胞壁扩展、维管束模式形成以及开花等生理过程。除了植物本身，与植物共生的微生物群落中的一些成员也能够合成或降解IAA，并以此影响与植物宿主的相互作用。例如有研究报道贪嗜菌属（Variovorax）是植物微生物群落中的核心成员，通过降解IAA调控植物激素水平来平衡菌群对根系生长的影响。据报道，80%的植物根际共生菌可合成IAA，这一小分子化合物有助于微生物在根系上的定殖。然而对于根际环境中，具有降解IAA能力的微生物有多少？它们降解IAA分子机制，以及它们在根际环境中扮演的角色还有待我们做进一步的研究。对于这些知识的理解将对我们开发更具抗逆性和高生产力的作物提供一种有前景的生态策略。 2024年12月10日，中国科学院深圳先进技术研究院合成微生物组学研究中心、深圳合成生物学创新研究院戴磊课题组在 PLOS Biology 期刊发表了题为：Systematic characterization of plant-associated bacteria that can degrade indole-3-acetic acid 的研究论文。该研究结合基因组学分析和体外实验的手段，系统性研究了从拟南芥和水稻根际分离培养的183株细菌对IAA降解的能力，并通过接种植物实验，探究了这些IAA降解菌的生物学意义。研究结果揭示了根际微生物代谢对植物生长发育过程的潜在影响，对于理解共生微生物与宿主互作机制具有重要意义。研究团队首先运用比较基因组学与体外降解实验相结合的方法，系统性评估了从拟南芥（Arabidopsis thaliana）和水稻（Oryza sativa）根部分离的183株细菌的IAA代谢能力。最终鉴定出来自7个属的共21株细菌具有IAA降解活性，其中包括之前未被报道过的新菌属（图1）。图1. 该研究用到的183株拟南芥和水稻根际共生细菌菌株的进化关系以及IAA降解功能预测、代谢检测。这些IAA降解菌株的基因组中，负责降解IAA的代谢基因簇为iac-like operon或iad-like operon（图2），通过转录组分析发现这些基因簇的表达受IAA诱导。值得注意的是，这些基因簇普遍受到一种在种间结构高度保守的调控子MarR（Multiple Antibiotic Resistance Regulator）的调控。图2. IAA降解相关基因簇的特征接着，研究团队发现部分IAA降解菌株可将IAA作为碳源使用。接种植物实验的结果表明，部分IAA降解菌株可以缓解环境中过高浓度IAA所引起的植物主根生长抑制现象（图3）。由此推断IAA降解菌在维持植物根际生长素浓度稳态方面可能有重要贡献，暗示IAA降解菌在根际微环境中对宿主植物的生长发育具有重要作用。图3. IAA降解菌可利用IAA并抑制IAA诱导的主根生长抑制现象最后，团队通过整合分析从不同生态环境收集的宏基因组装基因组（MAG）以及微生物分离株全基因组序列（WGS）中生物标志基因出现的频率，观察到IAA降解菌从水生环境到陆地环境，从土壤基质迈向植物体，并进一步由植物地上部分向根部逐渐增强的定殖偏好性趋势（图4），表明IAA降解菌与IAA生产者（包括植物与IAA合成微生物）之间可能存在密切的关联。图4. IAA降解菌在不同栖息地中的分布戴磊课题组助理研究员王兰香博士、客座学生刘月、研究助理倪浩然为论文共同第一作者，戴磊研究员和贵州大学陈沫先教授为论文共同通讯作者。该工作得到了国家自然科学基金国际（地区）合作与交流项目（No.32061143023）、广东省自然科学基金（No. 2023A1515012006）等项目，以及深圳合成生物学创新研究院的资助。论文链接： https://doi.org/10.1371/journal.pbio.3002921 设置星标，不错过精彩推文开放转载欢迎转发到朋友圈和微信群微信加群为促进前沿研究的传播和交流，我们组建了多个专业交流群，长按下方二维码，即可添加小编微信进群，由于申请人数较多，添加微信时请备注：学校/专业/姓名，如果是PI/教授，还请注明。点在看，传递你的品味

微生物疗法临床研究

2024-08-28

·PRNewswire

The Chemical Peel Market is projected to grow by USD 814.4 million from 2024 to 2028, driven by rising demand for aesthetic treatments and technological advancements, AI-powered report- Technavio

NEW YORK, Aug. 28, 2024 /PRNewswire/ -- Report on how AI is driving market transformation- The global chemical peel market size is estimated to grow by USD 814.4 millionn from 2024-2028, according to Technavio. The market is estimated to grow at a CAGR of 7.19% during the forecast period. Increasing demand for aesthetic procedures and technological advancement is driving market growth, with a trend towards increasing awareness about anti-aging measures. However, high cost of chemical peel products poses a challenge. Key market players include AbbVie Inc., AMOREPACIFIC Group Inc., Bausch Health Companies Inc., BeautyPharmaCo, Candela Corp., Caudalie International SE, Galderma SA, Hale Cosmeceuticals Inc, Image International Manufacturing LLC, Johnson and Johnson Services Inc., LOreal SA, MedPeel, Merz Pharma GmbH and Co KGaA, NEFTIS LABORATORIOS SL, Pierre Fabre SA, ProDerma Light, Radius Healthcare Pvt. Ltd., Renee Rouleau Inc., Topix Pharmaceuticals Inc., and Unilever PLC. Continue Reading Technavio has announced its latest market research report titled Global chemical peel market 2024-2028 Get a detailed analysis on regions, market segments, customer landscape, and companies - Click for the snapshot of this report Key Market Trends Fueling Growth The chemical peel market is experiencing significant growth due to the increasing awareness and demand for anti-aging procedures. In 2021 and 2022, there has been a rise in the number of cosmetic procedures performed in countries like the US, Brazil, Mexico, Germany, and Spain. This trend is driven by the advantages of chemical peels, including age spot reduction, sun damage removal, skin lightening, smoothening, and improved collagen growth. Vendors are actively promoting these benefits through various channels, such as websites, conferences, and magazine advertisements. Moreover, the increasing per capita income and economic development in emerging economies, particularly India and China, have led to a surge in online research and comparisons of various procedures. As a result, the chemical peel market is poised for continued growth during the forecast period. The Chemical Peel Market is witnessing significant growth due to the increasing demand for non-surgical skincare solutions. Trichloroacetic acid and Jessner's Solution are popular peeling agents used in chemical resurfacing for improving skin texture, reducing hyperpigmentation, acne scars, fine lines, and wrinkle reduction. These treatments are effective for sun damage, melasma treatment, and acne treatment. Medical aesthetics and cosmeceutical treatments using chemical formulations offer clinical benefits for various skin conditions. Glytone, Alpha hydroxy acid (AHA), sugar cane, sugar beets, lactic peel, milk, and Alpha-hydroxy acids (AHAs) are common peeling agents. Medium peels target the epidermis and dermis layers for enhanced skin health and beauty. The chemical peel procedure is a dermatologic treatment for skin health improvement and aesthetic enhancement. Discover a Comprehensive 360° Market Analysis: Understand the Impact of AI. For detailed information- Request Sample! Market Challenges The chemical peel market is currently facing a growth challenge due to the high cost of treatments, which is limiting its adoption, particularly in developing countries. The average price for a chemical peel ranges from USD600 to USD900, with significant variations depending on the type of peel. Light peels cost as low as USD150 but require multiple sessions for optimal results, while medium and deep peels can cost up to USD6,000. These high costs include fees for the chemical peel procedure, anesthesia, and operating room. The monopolistic approach of vendors, such as Allergan plc, in the market further contributes to the lack of competitive pricing. Allergan, a leading player in medical aesthetics, has acquired most of the market share, targeting high-income and upper-middle-class consumers. As a result, the inability of middle and lower-middle-class individuals to afford these costly procedures is hindering the growth of the global chemical peel market. The Chemical Peel market is thriving in the Skincare and Aesthetics industries, providing solutions for common concerns such as Acne, Pigmentation, and Wrinkle issues. Glytone's Peeling Solution, which contains Alpha Hydroxy Acids (AHAs) derived from Sugar Cane and Sugar Beets, is a popular choice for exfoliating the Epidermis. Medium Peels, using stronger Chemical Agents like TCA, reach deeper into the Dermis to address Acne spots, Dark Circles, and signs of Fatigue. Dermatology and Aesthetic Medicine professionals use these Dermatological Procedures for Skin Renewal, often combining different Chemical Compounds like Glycolic Acid, Lactic Acid, and Salicylic Acid for optimal results. The Beauty Industry continues to innovate with new Peeling Solutions, offering professional Chemical Exfoliation treatments for Facial Rejuvenation. For more insights on driver and challenges - Download a Sample Report Segment Overview This chemical peel market report extensively covers market segmentation by End-user 1.1 Hospital and recreation centers 1.2 Dermatology clinics Type 2.1 Light peel 2.2 Medium peel 2.3 Deep peel Geography 3.1 North America 3.2 Europe 3.3 APAC 3.4 South America 3.5 Middle East and Africa 1.1 Hospital and recreation centers- The Chemical Peel Market is experiencing steady growth due to increasing consumer awareness and demand for skin rejuvenation treatments. Businesses are offering various types of chemical peels to cater to diverse skin concerns, such as acne scars, aging, and sun damage. Market leaders are focusing on research and development to introduce innovative peel solutions and expand their customer base. Overall, the market is expected to continue its expansion in the coming years.For more information on market segmentation with geographical analysis including forecast (2024-2028) and historic data (2018 - 2022) - Download a Sample Report Research Analysis The Chemical Peel market encompasses a range of skincare treatments used in aesthetics to address various skin concerns, including acne, pigmentation, and wrinkle issues. These peels work by applying a chemical solution to the skin, causing it to exfoliate and peel off, revealing smoother, fresher skin. The solutions typically contain Alpha-hydroxy acids (AHAs) derived from fruits like glycolic acid from sugar cane and lactic peels from milk. Deeper peels may involve Phenol or Trichloroacetic acid, reaching the dermis for more significant results. Acne spots, dark circles, and signs of fatigue can also be targeted. Genetics and collagen production play a role in skin health, making chemical peels a popular choice for those seeking to improve their complexion in dermatology practices. Market Research Overview The Chemical Peel market encompasses a range of skincare treatments that utilize chemical solutions to improve the appearance of the skin. These peels are commonly used for various aesthetic concerns such as acne, pigmentation, and wrinkle issues. The solutions typically contain Alpha Hydroxy Acids (AHAs) derived from fruits like sugar cane and sugar beets, or Beta Hydroxy Acids (BHAs) like Salicylic Acid. The depth of the peel can vary from light to medium, affecting the epidermis or dermis layers. Chemical Peels are used to address acne spots, dark circles, fatigue, and signs of aging such as fine lines and wrinkles. The causes of these conditions can stem from genetics, sun damage, or lifestyle factors. The treatments promote collagen production, leading to skin renewal and texture improvement. Chemical Peels are considered a dermatological procedure and are also offered in aesthetic medicine clinics and the beauty industry. They provide a form of chemical exfoliation that goes beyond traditional cleansing methods. The solutions work by dissolving the bonds holding dead skin cells together, revealing smoother, healthier skin. Popular chemical peel formulations include Glytone, Jessner's Solution, TCA Peel, and various combinations of AHAs and BHAs. These treatments are administered as facial treatments in professional settings and are an essential part of medical aesthetics and cosmeceutical offerings. Chemical Peels contribute to skin health and beauty enhancement, addressing various skin conditions and concerns. They are an effective means of reducing hyperpigmentation, acne scars, sun damage, and melasma. The cosmetic procedure is a popular choice for individuals seeking wrinkle reduction and skin rejuvenation. Table of Contents: 1 Executive Summary 2 Market Landscape 3 Market Sizing 4 Historic Market Size 5 Five Forces Analysis 6 Market Segmentation End-user Hospital And Recreation Centers Dermatology Clinics Type Light Peel Medium Peel Deep Peel Geography North America Europe APAC South America Middle East And Africa 7 Customer Landscape 8 Geographic Landscape 9 Drivers, Challenges, and Trends 10 Company Landscape 11 Company Analysis 12 Appendix About Technavio Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contacts Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: SOURCE Technavio

2024-07-26

·佰傲谷BioValley

【八月福州合成】黄建忠教授讲解“高附加值氨基酸及其衍生物的生物合成”！

黄建忠福建师范大学生命科学学院教授工业微生物发酵技术国家地方联合工程研究中心主任 NO.01 职务介绍教授（二级）、博导、留日博士。现为“工业微生物发酵技术国家地方联合工程研究中心”主任、“工业微生物教育部工程研究中心”主任、“海西绿色生物制造技术省部共建协同创新中心”主任、福建省生物化学与分子生物学会理事长。入选福建省“百千万人才工程”。曾任“中国生物化学与分子生物学会工业生化与分子生物学分会”副理事长（2013-2018）。 NO.02 研究方向与成果从事工业微生物代谢育种与调控研究。主持国家重大专项、国家“863”、国家自然科学基金、福建省重大专项等30多项课题的研究。获中国专利优秀奖1项，福建省科技进步二等奖2项、三等奖2项，福建省自然科学优秀论文一等奖1篇、中国科协优秀学术论文奖1篇。发表160多篇论文，授权发明专利48项，制定行业标准5项，建立了多个产学联合体。 NO.03 代表论文 *仅举例其中5篇（1）Hongxuan Wu，Jinhua Yang，Peijie Shen，Qingchen Li，Weibin Wu，Xianzhang Jiang，Lina Qin，Jianzhong Huang*，Xiao Cao，Feng Qi*. High-Level Production of Indole-3-acetic Acid in the Metabolically Engineered Escherichia coli. Journal of Agricultural and Food Chemistry，2021，DOI: 10.1021/acs.jafc.0c08141 （2）Quanxiu Gao，Hao Chen，Gaoyan Wang，Wei Yang，Xiaotong Zhong，Jiezheng Liu，XiaoJing Huo，Weifeng Liu， Jianzhong Huang*，Yong Tao*， Baixue Lin*. Highly Efficient Production of Menaquinone‑7 from Glucose by Metabolically Engineered Escherichia coli. ACS Synthetic Biology，2021，DOI：10.1021/acssynbio.0c00568 （3） Wenji n Jia，Huan Li，Qian Wang，Kaixuan Zheng，Hong Lin，Xin Li，Jianzhong Huang*，Linting Xu，Wanqian Dong，Zhengyu Shu*. Screening of perhydrolases to optimize glucose oxidase-perhydrolase-in situ chemical oxidation cascade reaction system and its application in melanin decolorization. Journal of Biotechnology，2021，DOI: 10.1016/j.jbiotec.2021.01.013 （4）Mingliang Zhang， Huaidong Zhang*， Qin Li， Yangle Gao， Lijun Guo，Liu He，Shanshan Zang，Xing Guo，Jianzhong Huang*，Li Li*. Structural Insights into the Trans-Acting Enoyl Reductase in the Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Shewanella piezotolerans. Journal of Agricultural and Food Chemistry，2021，DOI ：10.1021/acs.jafc.0c07386 （5） Xiaolei Guo， Weibin Wu，·Mingliang Zhang，Licheng Wu，Jianzhong Huang*. A bi-enzymatic cascade to yield pyruvate as co-substrate for L-tyrosine production. Applied Microbiology and Biotechnology，2020，DOI ：10.1007/s00253-020-10975-4 *点击图片，跳转会议推文 FUZHOU 2024第一届合成生物技术与智能生物制造学术交流会暨中国微生物学会生化过程模型化与控制专业委员会年会 *上下滑动，查看更多议程点击“阅读原文”，查看更多精彩内容~

100 项与酢酸相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
D00010	酢酸	S02AA10 G01AD02	DB03166

研发状态

10 条进展最快的记录,

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适应症	最高研发状态	国家/地区	公司	日期
避孕	临床2期	中国	上海新亚药业闵行有限公司	2024-06-03
避孕	临床2期	中国	上海市生物医药技术研究院	2024-06-03

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


EADV2023	N/A	斑秃	40	Trichloroacetic Acid 35%	鹽觸鏇積糧製築鏇夢廠(繭艱鹹襯繭鹹襯夢淵襯) = 齋醖鹹鏇製襯鏇選壓壓繭鹽繭夢艱獵網廠選淵 (選鏇膚願餘醖獵選顧艱 )	积极	2023-10-11
TRICIN (ESGO2022)	临床2期	宫颈上皮内瘤样病变 HPV 16 \| other high risk types	102	85% TCA	醖壓鬱餘鹹網繭鹹餘鏇(鹹觸網衊鹽衊窪餘獵鏇) = 遞憲簾獵觸願鏇鏇淵蓋鹹齋繭網鑰鑰淵鏇廠艱 (願鬱繭鑰醖壓膚淵遞襯, 66.0 ~ 83.5) 更多	积极	2022-10-20
EADV2022	N/A	瘢痕	30	Trichloroacetic acid	觸夢蓋齋觸積鏇壓壓顧(鹽構顧衊積醖壓製構壓) = 齋醖夢鬱憲醖淵簾遞艱網壓襯鬱積醖艱窪糧範 (襯醖鹽襯糧製簾醖齋窪 )	-	2022-09-07
TECAIN (IAS2021)	N/A	肛门上皮内瘤变	155	topical trichloroacetic acid (Electrocautery)	膚繭窪艱顧遞顧繭糧願(窪蓋餘膚糧廠遞網鏇觸) = 襯窪鏇鏇壓觸築齋觸齋憲鏇夢鏇齋鑰餘窪觸鏇 (窪衊繭願憲簾觸窪淵衊 )	-	2021-01-01
TECAIN (IAS2021)	N/A	肛门上皮内瘤变	155	Topical trichloroacetic acid	膚繭窪艱顧遞顧繭糧願(窪蓋餘膚糧廠遞網鏇觸) = 製衊範願獵繭顧窪廠糧憲鏇夢鏇齋鑰餘窪觸鏇 (窪衊繭願憲簾觸窪淵衊 )	-	2021-01-01
NCT02614703 (CTgov)	临床2/3期	巴雷特食管	60	Chromoendoscopy using Acetic Acid 2.5% (Chromoendoscopy Using Acetic Acid 2.5%)	願艱醖獵選網觸淵觸糧(鏇蓋積夢蓋夢淵餘膚鹽) = 網願製獵鹽膚醖積窪簾築構觸窪構鹹願糧窪壓 (襯築淵淵鏇衊壓夢獵簾, 夢淵選艱衊壓遞衊齋夢 ~ 糧齋網製餘築製網襯範) 更多	-	2019-08-26
NCT02614703 (CTgov)	临床2/3期	巴雷特食管	60	Standard random esophageal biopsies (Standard Random Esophageal Biopsies)	願艱醖獵選網觸淵觸糧(鏇蓋積夢蓋夢淵餘膚鹽) = 顧選鏇鹽觸鹽衊繭觸選築構觸窪構鹹願糧窪壓 (襯築淵淵鏇衊壓夢獵簾, 憲遞鹹壓選衊夢衊鏇鹹 ~ 鑰鹽壓壓蓋簾齋廠壓範) 更多	-	2019-08-26
ISN WCN2019	N/A	腹膜疾病	-	Acetic acid (2%)	繭艱積糧製鹹鹹窪膚襯(鬱願窪鹹遞積齋蓋網遞) = 壓襯遞製齋觸憲壓獵憲鹽鹽簾醖窪齋廠衊糧積 (積餘窪鹽願製醖醖廠衊, 44.4)	-	2019-07-01
ISN WCN2019	N/A	腹膜疾病	-	Mupirocin	繭艱積糧製鹹鹹窪膚襯(鬱願窪鹹遞積齋蓋網遞) = 簾製蓋襯襯範餘獵壓憲鹽鹽簾醖窪齋廠衊糧積 (積餘窪鹽願製醖醖廠衊, 37.1)	-	2019-07-01