预约演示

更新于：2025-05-16

Acetic Acid, Glacial

酢酸

更新于：2025-05-16

概要

基本信息

药物类型

小分子化药

别名

Acetic Acid、Acetic acid (JP17/NF)、Acetic acid, glacial (USP)

+ [16]

靶点-

作用方式-

作用机制-

治疗领域

其他疾病

在研适应症

避孕

非在研适应症-

原研机构

Akorn Operating Co. LLC

在研机构

上海新亚药业闵行有限公司Akorn Operating Co. LLC

上海市生物医药技术研究院

+ [4]

非在研机构-

权益机构-

最高研发阶段批准上市

首次获批日期

美国 (1960-05-17)

最高研发阶段(中国)批准上市

特殊审评-

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结构/序列

分子式C2H4O2

InChIKeyQTBSBXVTEAMEQO-UHFFFAOYSA-N

CAS号64-19-7

关联

项与酢酸相关的临床试验

CTRI/2025/03/082838

/ Not yet recruitingN/AIIT

A split face comparative study to evaluate the efficacy of Microneedling versus 15 percent Trichloroacetic acid in Acne scars - NIL

开始日期2025-04-01

申办/合作机构-

NCT06297967

/ Not yet recruiting临床3期IIT

Acetic Acid in Cutaneous Ulcers. a Randomized Controlled Trial

The objective of this clinical trial is to assess the effectiveness of acetic acid in patients suffering from chronic cutaneous ulcers with biofilm. The primary question it seeks to address is whether acetic acid (as a 2% topical solution) is superior to the current standard treatment for chronic cutaneous ulcers with biofilm at our center (Prontosan®).
Participants will be randomly assigned to receive either the acetic acid solution treatment or the standard current treatment.

开始日期2025-03-01

申办/合作机构-

NCT06525870

/ Enrolling by invitation临床2期IIT

Efficacy of Topical 85%Trichloroacetic Acid in the Treatment of Low-grade Squamous Intraepithelial Lesion (LSIL) After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial

To determine the efficacy and HPV clearance of an application of 85% TCA compared to placebo in the treatment of LSIL. This is a randomized, single-blind, placebo-controlled study in 44 women aged 18-65 years with histologic-proved HPV/CIN1. The study will test whether 85% TCA application will be effective treatment in LSIL. The clinical study hypothesis is that TCA application at cervical lesion and transformation zone will achieve histologic complete remission of LSIL in significantly more patients than placebo therapy. Patients will be randomized to placebo (3% acetic acid) or 85%TCA topical application at cervical lesion and transformation zone. After 3 months, cytology, colposcopy, histology, and HPV testing will be performed. The primary endpoint is treatment efficacy defined as complete histologic remission at 3 months after treatment. The secondary endpoint is HPV clearance 3 months after treatment. The protocol for the project is approved by an Institutional Review Board (IRB). Project is totally supported by a grant from Rajavithi Hospital. There is no external funding.

开始日期2024-08-01

申办/合作机构

Rajavithi Hospital

100 项与酢酸相关的临床结果

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100 项与酢酸相关的转化医学

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100 项与酢酸相关的专利（医药）

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224,915

项与酢酸相关的文献（医药）

2025-12-31·Bioengineered

Fractionation of waste-derived volatile fatty acids by multi-stage adsorption using activated charcoal and Diaion HP-20 resin

Article

作者: Taherzadeh, Mohammad J. ; Wainaina, Steven ; Basereh, Negar ; Mahboubi, Amir

Substituting waste-derived Volatile Fatty Acids (VFAs) with their conventionally applied fossil-derived counterparts in a spectrum of industrial applications necessitates its proper fractionation into individual acids. This study explored a multi-stage batch adsorption approach for fractionating acidogenic fermentation VFAs effluents from food waste (FW) and chicken manure (CKM) using Diaion HP-20 and activated charcoal. Initial screening at different washing conditions and pH (3.5 and 6.5) revealed the unwashed granular-activated charcoal (GAC-Unwashed) and milli-Q water-washed Diaion (DI-MQ Washed) as the most promising candidates for VFA fractionation of a synthetic VFA mixture at 4 gL^-1. At pH 3.5 (__-mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"-__<pKa), GAC-Unwashed adsorbed 2-6 carbon atom VFAs completely, while DI-MQ Washed exhibited minimal adsorption of acetic acid (AA) (8%), favoring caproic (CA) and valeric acids (VA) (__-mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"-__>97%). While at pH 6.5 __-mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"-__(>pKa), GAC-Unwashed selectively targeted VA (79%) and CA (100%). Fractionating VFAs from FW and CKM were conducted in a two-stage adsorption process with optimal results being achieved using GAC-Unwashed at FW initial pH (5.3) and DI-MQ Washed at pH below CKM __-mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"-__pKa (3.5), respectively. The first adsorption stage primarily adsorbed higher molecular weight (MW) VFAs (FW:99.1% CA, CKM:72.9% butyric acid (BA)) with a minor quantity of lower ones (FW:56.5% BA, CKM:29.3% propionic acid (PA)), leaving AA intact. Subsequent stages aimed to isolate AA by adsorbing the remaining low MW VFA (FW:58.9% BA, CKM:27.8% PA, 70% BA) other than AA, indicating effluent fractionation while preserving and purifying AA. Applied selective multi-stage adsorption approach offers a promising method to broaden waste-derived VFA applications.

2025-12-31·CyTA-Journal of Food

Phytochemical composition, phytotoxicity, and ADME modeling of Artemisia absinthium L.: implications for food safety and pharmaceutical applications

作者: Benali, Mohammed ; Gharibi, Elkhadir ; Mothana, Ramzi A. ; Ed-darraz, Fatima-Zahrae ; Bouyanzer, Abdelhamid ; Farihi, Ayoub ; Hawwal, Mohammed F. ; Hbika, Asmae

Artemisia absinthium, an aromatic herb distinguished by its characteristic bitter flavor, has been used in a variety of culinary applications.This study investigates its metabolites through phytochem. methods.The primary minerals in Artemisia absinthium stems are potassium (41%) and calcium (38.3%), forming most of its mineral content.The ethanolic extract exhibited the highest phenolic compound content, with 37.6 ± 0.09 mg GAE/g DE.The primary volatile compound identified was β-thujone, comprising over 26.6% of the volatile content.Palmitic acid is the predominant fatty acid in the hexanic extract (18.7%), while linoleic acid is the main fatty acid in the Et acetate extract (42.4%).Twenty phenolic compounds were identified, with 8-methoxyflavone, (+)-catechin hydrate, and chlorogenic acid as major compounds in dichloromethane, Et acetate, and ethanol extracts, resp.ADME modeling indicating that 8-methoxyflavone, a major component in the dichloromethane extract, is a promising candidate for drug development targeting the central nervous system.

2025-12-31·Energy Sources Part A-Recovery Utilization and Environmental Effects

Simultaneous improvement in qualities of bio-oil and syngas from catalytic pyrolysis of rice husk by demineralization

作者: Wang, Zhongwen ; Xiong, Yuanquan

This study aims to investigate the influences of different demineralization pretreatment processes on the properties of liquid and gas products from catalytic pyrolysis via activated carbon catalyst.To achieve this goal, deionized water, hydrochloric acid, and acetic acid were used to remove ash.The results indicated that leaching could remove a large amount of alkali and alk. earth metals (AAEMs).Besides, the experiments of different leaching solutions on catalytic fast pyrolysis of rice husks were conducted.It can be found that compared with direct pyrolysis, the catalytic pyrolysis produced more gas products, in which CO increased by 6.49%, while the bio-oil was concentrated in phenols (more than 90%).After demineralization, the content of CO in gas products further increased by 8.04%, while the relative content of phenol in bio-oil enhanced by 14.79% as well.Catalysis can enrich phenol in bio-oil, and leaching can enhance this enrichment.Meanwhile, demineralization can further improve the quality of syngas.The sample after demineralization by hydrochloric acid performed best on catalytic fast pyrolysis, where CO accounts for 57.68% volume of gaseous product and phenol accounted for 68.21% of bio-oil.

项与酢酸相关的新闻（医药）

2025-03-10

·药事纵横

制剂研究员向溶液里加了一滴醋，领导说今年绩效给A+

一、前言醋酸（Acetic acid，又名乙酸，化学式CH3COOH）是一种弱酸，在水溶液中可部分电离生成醋酸根离子和氢离子，在常温下为无色透明液体。在制药领域，醋酸是十分常用的一种有机化学试剂，如用于缓冲液配制、调节溶液pH等。但是鲜有制剂研究人员知道醋酸在药物制剂处方开发中的妙用。毫不夸张地说，醋酸这种毫不起眼的化学试剂可以使某些濒临“死亡”的制剂开发项目起死回生，极大地推进项目进度。下面，笔者就将结合个人的实际项目经验以及案例谈一谈醋酸在药物制剂处方开发中的应用，希望对从事药物制剂研发的读者有所启发。二、案例分享 2.1醋酸在环糊精包合物制备中的应用对于某些难溶性的药物，将其制备成环糊精包合物是提高其溶解度的一种有效的制剂手段。但是，实际做过此类项目的人都知道很多时候药物是无法直接完全溶于环糊精溶液中的，往往不得降低载药量，而载药量降低又可能会导致后期制剂（如片剂）的体积过大。而且，往往很多时候包合效率（complexation efficiency, CE）不尽如人意，导致你得到的所谓的“包合物”中其实还含有大量的没有包封药物的游离的环糊精分子，只有部分环糊精分子与药物包合形成了真正的包合物。还有些研究员会尝试添加有机溶剂（如乙醇），虽然此法可提高药物表观固有溶解度（apparent intrinsic solubility, S0）促进包合反应平衡向包合方向移动，但有机溶剂分子会与药物分子竞争环糊精空腔，降低药物/环糊精包合物的表观稳定性常数（apparent stability constant, Kc），导致整体包合效率下降。对于一些碱性药物，若想制备环糊精包合物，醋酸就是一种绝佳的“佐料”（而对于酸性药物则是氨水，由于本文的主角是醋酸，故在本文先按下不表）。其原理是，挥发性弱酸（例如醋酸）加入弱碱性药物的水性包合体系，或者把挥发性弱碱（例如氨水）加入弱酸性药物的水性包合体系时，酸碱会促使药物发生电离。药物电离后，其表观固有溶解度S0增大，溶液中能溶解的药物分子增多。根据包合反应平衡原理，S0增大（相当于增加了反应物浓度），会推动包合反应平衡向生成药物与环糊精包合物的方向移动，从而暂时提高包合效率。当完成包合后，通过干燥（例如真空干燥）将引入的挥发性酸或碱（例如醋酸和氨水）去除。此时，药物又恢复到非离子化状态，最终得到非离子化的药物/环糊精包合物。案例1抗抑郁药物AR-A000002 AR-A000002是阿斯利康（AstraZeneca）研发的一款选择性5-羟色胺受体拮抗剂。AR-A000002是一种弱碱性药物（pKa=8.3），其化学结构如图1所示。图1 AR-A000002化学结构该药物水溶性差，其环糊精包合物制备是将AR-A000002分别与等摩尔的羟丙基-β-环糊精（HP-β-CD）进行包合，并向包合体系中加入20当量的醋酸促进药物溶解。药物溶解后通过冻干将包合溶液固化，得到药物的包合物。冻干后药物、环糊精和醋酸的摩尔比约为1:1:1，在真空烘箱中88℃加热7小时后醋酸含量降至约0.1当量，继续加热至20天，残留的醋酸含量缓慢降至0.08当量。图2添加醋酸制备的包合物、未添加醋酸制备的包合物以及纯药物溶出曲线溶出实验结果表明，添加醋酸制备的AR-A000002/HP-β-CD包合物溶出迅速（图2黑色圆圈），能形成过饱和溶液，可释放约45%的药物，且该过饱和溶液在沉淀前能稳定存在约10小时；而未添加醋酸制备的包合物则不能形成过饱和溶液（图2白色圆圈），药物AR-A000002（图2白色方框）溶解非常缓慢。 2.2醋酸在喷雾干燥固体分散体中的应用笔者参与过多个喷雾干燥固体分散体项目，最令笔者头疼的一个问题就是现在越来越多的新药溶解度非常差。在早期进行溶剂筛选时，有些药物在常用的有机溶剂（如乙醇、甲醇、丙酮、二氯甲烷、四氢呋喃、甲醇/二氯甲烷混合溶剂等）中溶解度很低，这就导致后期放大生产时需要使用大量的有机溶剂，限制了生产效率，增加了生产成本。对于弱碱性药物，可使用挥发性酸通过电离作用提高药物在喷雾干燥溶剂中的溶解度，并且在真空干燥后，挥发性酸会挥发，使药物能够重新转变为游离形式。醋酸是一种非常合适的挥发性酸，因为它的pKa适中（4.75），与诸如盐酸等强酸相比，它与弱碱性药物的结合并不紧密。而盐酸等强酸由于强化学键的作用，不太可能从碱性药物上解离，而醋酸则可以在后续真空干燥过程中挥发，使药物恢复为游离碱形式。案例2靶向抗癌药物吉非替尼 Lonza公司的研究人发现对于一种弱碱性药物吉非替尼（pKa=7.2，化学结构如图3所示），醋酸能够通过使其电离形成瞬态醋酸盐，将其在MeOH:H2O喷干溶剂中的溶解度提高10倍（醋酸用量20mg/mL）。图3吉非替尼化学结构醋酸在后续真空干燥过程中会被去除，最终得到的吉非替尼喷雾干燥分散体，其性能与未使用醋酸制备的喷雾干燥分散体相似，在形态（通过SEM观察）、药物的无定形状态（通过PXRD检测）、玻璃化转变温度（通过mDSC测定）方面相似，体外溶出也无明显差异，说明醋酸的使用对吉非替尼喷雾干燥分散体的特性没有显著影响，预期在体内的性能也相似。因此，我们可以看到仅仅通过在喷雾干燥溶剂中添加醋酸就使药物的溶解度得到了显著的提高，不仅提高生产效率和减少所需溶剂量，使得一些难溶性药物药物能够实现大规模生产，也有利于践行绿色可持续发展以及环境保护。参考文献 [1] Loftsson T, Sigurdsson HH, Másson M, Schipper N. Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs. Pharmazie. 2004 Jan;59(1):25-9. [2] Adam MS, Miller WK, Pluntze AM, Stewart AM, Cape JL, Grass ME, Morgen MM. Acetic Acid as Processing Aid Dramatically Improves Organic Solvent Solubility of Weakly Basic Drugs for Spray Dried Dispersion Manufacture. Pharmaceutics. 2022 Mar 2;14(3):555. 药事纵横投稿须知：稿费已上调，欢迎投稿

2024-12-13

·生物世界

PLOS Biology：戴磊/陈沫先团队揭示植物根际微生物对生长素的分解代谢

编辑丨王多鱼排版丨水成文生长素（auxins）是植物体内一类重要的激素，广泛参与调控植物的生长、发育及应答外部环境的变化。生长素的研究始于19世纪末，是最早被发现的植物激素之一。作为主要的天然生长素分子，吲哚-3-乙酸（IAA）在植物中含量最为丰富，并在植物的多个发育过程中发挥关键作用，包括细胞分裂、根系发育、细胞壁扩展、维管束模式形成以及开花等生理过程。除了植物本身，与植物共生的微生物群落中的一些成员也能够合成或降解IAA，并以此影响与植物宿主的相互作用。例如有研究报道贪嗜菌属（Variovorax）是植物微生物群落中的核心成员，通过降解IAA调控植物激素水平来平衡菌群对根系生长的影响。据报道，80%的植物根际共生菌可合成IAA，这一小分子化合物有助于微生物在根系上的定殖。然而对于根际环境中，具有降解IAA能力的微生物有多少？它们降解IAA分子机制，以及它们在根际环境中扮演的角色还有待我们做进一步的研究。对于这些知识的理解将对我们开发更具抗逆性和高生产力的作物提供一种有前景的生态策略。 2024年12月10日，中国科学院深圳先进技术研究院合成微生物组学研究中心、深圳合成生物学创新研究院戴磊课题组在 PLOS Biology 期刊发表了题为：Systematic characterization of plant-associated bacteria that can degrade indole-3-acetic acid 的研究论文。该研究结合基因组学分析和体外实验的手段，系统性研究了从拟南芥和水稻根际分离培养的183株细菌对IAA降解的能力，并通过接种植物实验，探究了这些IAA降解菌的生物学意义。研究结果揭示了根际微生物代谢对植物生长发育过程的潜在影响，对于理解共生微生物与宿主互作机制具有重要意义。研究团队首先运用比较基因组学与体外降解实验相结合的方法，系统性评估了从拟南芥（Arabidopsis thaliana）和水稻（Oryza sativa）根部分离的183株细菌的IAA代谢能力。最终鉴定出来自7个属的共21株细菌具有IAA降解活性，其中包括之前未被报道过的新菌属（图1）。图1. 该研究用到的183株拟南芥和水稻根际共生细菌菌株的进化关系以及IAA降解功能预测、代谢检测。这些IAA降解菌株的基因组中，负责降解IAA的代谢基因簇为iac-like operon或iad-like operon（图2），通过转录组分析发现这些基因簇的表达受IAA诱导。值得注意的是，这些基因簇普遍受到一种在种间结构高度保守的调控子MarR（Multiple Antibiotic Resistance Regulator）的调控。图2. IAA降解相关基因簇的特征接着，研究团队发现部分IAA降解菌株可将IAA作为碳源使用。接种植物实验的结果表明，部分IAA降解菌株可以缓解环境中过高浓度IAA所引起的植物主根生长抑制现象（图3）。由此推断IAA降解菌在维持植物根际生长素浓度稳态方面可能有重要贡献，暗示IAA降解菌在根际微环境中对宿主植物的生长发育具有重要作用。图3. IAA降解菌可利用IAA并抑制IAA诱导的主根生长抑制现象最后，团队通过整合分析从不同生态环境收集的宏基因组装基因组（MAG）以及微生物分离株全基因组序列（WGS）中生物标志基因出现的频率，观察到IAA降解菌从水生环境到陆地环境，从土壤基质迈向植物体，并进一步由植物地上部分向根部逐渐增强的定殖偏好性趋势（图4），表明IAA降解菌与IAA生产者（包括植物与IAA合成微生物）之间可能存在密切的关联。图4. IAA降解菌在不同栖息地中的分布戴磊课题组助理研究员王兰香博士、客座学生刘月、研究助理倪浩然为论文共同第一作者，戴磊研究员和贵州大学陈沫先教授为论文共同通讯作者。该工作得到了国家自然科学基金国际（地区）合作与交流项目（No.32061143023）、广东省自然科学基金（No. 2023A1515012006）等项目，以及深圳合成生物学创新研究院的资助。论文链接： https://doi.org/10.1371/journal.pbio.3002921 设置星标，不错过精彩推文开放转载欢迎转发到朋友圈和微信群微信加群为促进前沿研究的传播和交流，我们组建了多个专业交流群，长按下方二维码，即可添加小编微信进群，由于申请人数较多，添加微信时请备注：学校/专业/姓名，如果是PI/教授，还请注明。点在看，传递你的品味

微生物疗法临床研究

2024-08-28

·PRNewswire

The Chemical Peel Market is projected to grow by USD 814.4 million from 2024 to 2028, driven by rising demand for aesthetic treatments and technological advancements, AI-powered report- Technavio

NEW YORK, Aug. 28, 2024 /PRNewswire/ -- Report on how AI is driving market transformation- The global chemical peel market size is estimated to grow by USD 814.4 millionn from 2024-2028, according to Technavio. The market is estimated to grow at a CAGR of 7.19% during the forecast period. Increasing demand for aesthetic procedures and technological advancement is driving market growth, with a trend towards increasing awareness about anti-aging measures. However, high cost of chemical peel products poses a challenge. Key market players include AbbVie Inc., AMOREPACIFIC Group Inc., Bausch Health Companies Inc., BeautyPharmaCo, Candela Corp., Caudalie International SE, Galderma SA, Hale Cosmeceuticals Inc, Image International Manufacturing LLC, Johnson and Johnson Services Inc., LOreal SA, MedPeel, Merz Pharma GmbH and Co KGaA, NEFTIS LABORATORIOS SL, Pierre Fabre SA, ProDerma Light, Radius Healthcare Pvt. Ltd., Renee Rouleau Inc., Topix Pharmaceuticals Inc., and Unilever PLC. Continue Reading Technavio has announced its latest market research report titled Global chemical peel market 2024-2028 Get a detailed analysis on regions, market segments, customer landscape, and companies - Click for the snapshot of this report Key Market Trends Fueling Growth The chemical peel market is experiencing significant growth due to the increasing awareness and demand for anti-aging procedures. In 2021 and 2022, there has been a rise in the number of cosmetic procedures performed in countries like the US, Brazil, Mexico, Germany, and Spain. This trend is driven by the advantages of chemical peels, including age spot reduction, sun damage removal, skin lightening, smoothening, and improved collagen growth. Vendors are actively promoting these benefits through various channels, such as websites, conferences, and magazine advertisements. Moreover, the increasing per capita income and economic development in emerging economies, particularly India and China, have led to a surge in online research and comparisons of various procedures. As a result, the chemical peel market is poised for continued growth during the forecast period. The Chemical Peel Market is witnessing significant growth due to the increasing demand for non-surgical skincare solutions. Trichloroacetic acid and Jessner's Solution are popular peeling agents used in chemical resurfacing for improving skin texture, reducing hyperpigmentation, acne scars, fine lines, and wrinkle reduction. These treatments are effective for sun damage, melasma treatment, and acne treatment. Medical aesthetics and cosmeceutical treatments using chemical formulations offer clinical benefits for various skin conditions. Glytone, Alpha hydroxy acid (AHA), sugar cane, sugar beets, lactic peel, milk, and Alpha-hydroxy acids (AHAs) are common peeling agents. Medium peels target the epidermis and dermis layers for enhanced skin health and beauty. The chemical peel procedure is a dermatologic treatment for skin health improvement and aesthetic enhancement. Discover a Comprehensive 360° Market Analysis: Understand the Impact of AI. For detailed information- Request Sample! Market Challenges The chemical peel market is currently facing a growth challenge due to the high cost of treatments, which is limiting its adoption, particularly in developing countries. The average price for a chemical peel ranges from USD600 to USD900, with significant variations depending on the type of peel. Light peels cost as low as USD150 but require multiple sessions for optimal results, while medium and deep peels can cost up to USD6,000. These high costs include fees for the chemical peel procedure, anesthesia, and operating room. The monopolistic approach of vendors, such as Allergan plc, in the market further contributes to the lack of competitive pricing. Allergan, a leading player in medical aesthetics, has acquired most of the market share, targeting high-income and upper-middle-class consumers. As a result, the inability of middle and lower-middle-class individuals to afford these costly procedures is hindering the growth of the global chemical peel market. The Chemical Peel market is thriving in the Skincare and Aesthetics industries, providing solutions for common concerns such as Acne, Pigmentation, and Wrinkle issues. Glytone's Peeling Solution, which contains Alpha Hydroxy Acids (AHAs) derived from Sugar Cane and Sugar Beets, is a popular choice for exfoliating the Epidermis. Medium Peels, using stronger Chemical Agents like TCA, reach deeper into the Dermis to address Acne spots, Dark Circles, and signs of Fatigue. Dermatology and Aesthetic Medicine professionals use these Dermatological Procedures for Skin Renewal, often combining different Chemical Compounds like Glycolic Acid, Lactic Acid, and Salicylic Acid for optimal results. The Beauty Industry continues to innovate with new Peeling Solutions, offering professional Chemical Exfoliation treatments for Facial Rejuvenation. For more insights on driver and challenges - Download a Sample Report Segment Overview This chemical peel market report extensively covers market segmentation by End-user 1.1 Hospital and recreation centers 1.2 Dermatology clinics Type 2.1 Light peel 2.2 Medium peel 2.3 Deep peel Geography 3.1 North America 3.2 Europe 3.3 APAC 3.4 South America 3.5 Middle East and Africa 1.1 Hospital and recreation centers- The Chemical Peel Market is experiencing steady growth due to increasing consumer awareness and demand for skin rejuvenation treatments. Businesses are offering various types of chemical peels to cater to diverse skin concerns, such as acne scars, aging, and sun damage. Market leaders are focusing on research and development to introduce innovative peel solutions and expand their customer base. Overall, the market is expected to continue its expansion in the coming years.For more information on market segmentation with geographical analysis including forecast (2024-2028) and historic data (2018 - 2022) - Download a Sample Report Research Analysis The Chemical Peel market encompasses a range of skincare treatments used in aesthetics to address various skin concerns, including acne, pigmentation, and wrinkle issues. These peels work by applying a chemical solution to the skin, causing it to exfoliate and peel off, revealing smoother, fresher skin. The solutions typically contain Alpha-hydroxy acids (AHAs) derived from fruits like glycolic acid from sugar cane and lactic peels from milk. Deeper peels may involve Phenol or Trichloroacetic acid, reaching the dermis for more significant results. Acne spots, dark circles, and signs of fatigue can also be targeted. Genetics and collagen production play a role in skin health, making chemical peels a popular choice for those seeking to improve their complexion in dermatology practices. Market Research Overview The Chemical Peel market encompasses a range of skincare treatments that utilize chemical solutions to improve the appearance of the skin. These peels are commonly used for various aesthetic concerns such as acne, pigmentation, and wrinkle issues. The solutions typically contain Alpha Hydroxy Acids (AHAs) derived from fruits like sugar cane and sugar beets, or Beta Hydroxy Acids (BHAs) like Salicylic Acid. The depth of the peel can vary from light to medium, affecting the epidermis or dermis layers. Chemical Peels are used to address acne spots, dark circles, fatigue, and signs of aging such as fine lines and wrinkles. The causes of these conditions can stem from genetics, sun damage, or lifestyle factors. The treatments promote collagen production, leading to skin renewal and texture improvement. Chemical Peels are considered a dermatological procedure and are also offered in aesthetic medicine clinics and the beauty industry. They provide a form of chemical exfoliation that goes beyond traditional cleansing methods. The solutions work by dissolving the bonds holding dead skin cells together, revealing smoother, healthier skin. Popular chemical peel formulations include Glytone, Jessner's Solution, TCA Peel, and various combinations of AHAs and BHAs. These treatments are administered as facial treatments in professional settings and are an essential part of medical aesthetics and cosmeceutical offerings. Chemical Peels contribute to skin health and beauty enhancement, addressing various skin conditions and concerns. They are an effective means of reducing hyperpigmentation, acne scars, sun damage, and melasma. The cosmetic procedure is a popular choice for individuals seeking wrinkle reduction and skin rejuvenation. Table of Contents: 1 Executive Summary 2 Market Landscape 3 Market Sizing 4 Historic Market Size 5 Five Forces Analysis 6 Market Segmentation End-user Hospital And Recreation Centers Dermatology Clinics Type Light Peel Medium Peel Deep Peel Geography North America Europe APAC South America Middle East And Africa 7 Customer Landscape 8 Geographic Landscape 9 Drivers, Challenges, and Trends 10 Company Landscape 11 Company Analysis 12 Appendix About Technavio Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contacts Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: SOURCE Technavio

100 项与酢酸相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
D00010	酢酸	S02AA10 G01AD02	DB03166

研发状态

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适应症	最高研发状态	国家/地区	公司	日期
避孕	临床2期	中国	上海新亚药业闵行有限公司	2024-06-03
避孕	临床2期	中国	上海市生物医药技术研究院	2024-06-03

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临床结果

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


EADV2023	N/A	斑秃	40	Trichloroacetic Acid 35%	衊廠鹹製醖網繭蓋襯繭(積艱憲鏇築簾觸願夢襯) = 遞衊膚願淵網選襯窪顧積襯餘遞獵蓋製顧製願 (顧淵鏇壓範網糧廠齋蓋 )	积极	2023-10-11
TRICIN (ESGO2022)	临床2期	宫颈上皮内瘤样病变 HPV 16 \| other high risk types	102	85% TCA	構艱簾齋餘憲鏇齋壓簾(窪構製鹽簾繭範夢鏇憲) = 構襯艱願廠壓網醖膚範艱顧鬱範構醖衊糧獵壓 (積願壓鹹艱醖醖鹹顧蓋, 66.0 ~ 83.5) 更多	积极	2022-10-20
EADV2022	N/A	瘢痕	30	Trichloroacetic acid	觸遞願築觸製糧憲窪夢(膚鬱網鹹選齋蓋餘繭鬱) = 簾鏇蓋繭鹹顧觸簾襯選夢網膚築獵築鏇夢鑰願 (壓鏇願繭顧網鏇窪廠繭 )	-	2022-09-07
TECAIN (IAS2021)	N/A	肛门上皮内瘤变	155	topical trichloroacetic acid (Electrocautery)	壓醖簾衊願糧獵遞艱觸(構鹽壓鏇觸蓋遞憲醖觸) = 壓夢築遞製醖鹽餘鏇襯醖夢醖蓋蓋廠積憲廠糧 (夢衊廠齋觸鹽積餘鹹鏇 )	-	2021-01-01
TECAIN (IAS2021)	N/A	肛门上皮内瘤变	155	Topical trichloroacetic acid	壓醖簾衊願糧獵遞艱觸(構鹽壓鏇觸蓋遞憲醖觸) = 鹽膚醖齋獵築蓋鹹選鹽醖夢醖蓋蓋廠積憲廠糧 (夢衊廠齋觸鹽積餘鹹鏇 )	-	2021-01-01
NCT02614703 (CTgov)	临床2/3期	巴雷特食管	60	Chromoendoscopy using Acetic Acid 2.5% (Chromoendoscopy Using Acetic Acid 2.5%)	遞齋鹽顧築衊遞糧範獵 = 膚糧積壓鑰淵簾醖構衊衊夢繭願憲觸憲觸齋選 (選繭窪鬱願憲廠願壓襯, 選簾淵壓衊繭艱積壓繭 ~ 淵鹹鬱糧願獵壓憲構憲) 更多	-	2019-08-26
NCT02614703 (CTgov)	临床2/3期	巴雷特食管	60	Standard random esophageal biopsies (Standard Random Esophageal Biopsies)	遞齋鹽顧築衊遞糧範獵 = 衊觸選網憲築憲壓憲襯衊夢繭願憲觸憲觸齋選 (選繭窪鬱願憲廠願壓襯, 鬱獵窪齋餘構構遞窪壓 ~ 夢獵繭鹽衊鬱壓選選築) 更多	-	2019-08-26
ISN WCN2019	N/A	腹膜疾病	-	Acetic acid (2%)	淵夢憲鬱顧鑰艱選憲網(鹹廠鹹範襯選觸願淵憲) = 鏇網願衊淵餘顧鏇襯網鑰觸網選鏇鹽繭構鏇積 (網範簾衊艱遞構獵繭鹽, 44.4)	-	2019-07-01
ISN WCN2019	N/A	腹膜疾病	-	Mupirocin	淵夢憲鬱顧鑰艱選憲網(鹹廠鹹範襯選觸願淵憲) = 壓築餘憲網遞衊選獵製鑰觸網選鏇鹽繭構鏇積 (網範簾衊艱遞構獵繭鹽, 37.1)	-	2019-07-01