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更新于：2026-01-04
Ustekinumab-hmny
乌司奴单抗生物类似药（百奥泰）
更新于：2026-01-04
概要
基本信息
原研机构 |
非在研机构- |
最高研发阶段批准上市 |
最高研发阶段(中国)申请上市 |
特殊审评- |
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结构/序列
Sequence Code 143665H
当前序列信息引自: *****
Sequence Code 143874L
当前序列信息引自: *****
关联
6
项与 乌司奴单抗生物类似药（百奥泰） 相关的临床试验NCT05186623
Establishment of Prediction Model of Biologics and Small Molecular Agent for Patients With Ulcerative Colitis Using Longitudinal Data
This prospective observational study is going to develop and validate a prediction model of response to biologic agents and small molecular agents for Korean patients with ulcerative colitis.
开始日期2022-02-05 |
申办/合作机构 |
NCT04728360
A Multicenter, Randomized, Double-Blind, Parallel-Arm, Phase 3 Study to Compare Efficacy and Safety of BAT2206 With Stelara® in Patients With Moderate to Severe Plaque Psoriasis
This study is a multicenter, randomized, double-blind, parallel-arm, Phase 3 study designed to compare efficacy, safety, immunogenicity, and PK of BAT2206 with Stelara in patients with moderate to severe plaque psoriasis.
The study is composed of a ≤ 28-day screening period, a 16-week initial treatment period (TP1), a 24-week secondary treatment period (TP2), a 12-week efficacy and safety follow-up period up to end-of-study visit, for a maximum total study duration of 56 weeks.
The study is composed of a ≤ 28-day screening period, a 16-week initial treatment period (TP1), a 24-week secondary treatment period (TP2), a 12-week efficacy and safety follow-up period up to end-of-study visit, for a maximum total study duration of 56 weeks.
开始日期2021-07-06 |
申办/合作机构 |
NCT04371185
A Randomized, Double-blinded, Single-dose, 3-arms Parallel, Comparative Study to Evaluate the Pharmacokinetics and Safety of BAT2206 Injection vs Ustekinumab Injection (Stelara) in Healthy Chinese Male Subjects
It is a randomized, double-blinded, single-dose, 3-arm parallel, comparative study to evaluate the pharmacokinetics, safety and immunogenicity of BAT2206 Injection vs Stelara® (EU-licensed and US-licensed) in healthy Chinese male subjects. A total of 270 healthy male subjects are planned to be included and randomized at a ratio of 1:1:1 to receive single 45mg/0.5ml BAT2206 Injection or Stelara® (EU-licensed and US-licensed).
开始日期2020-08-08 |
申办/合作机构 |
100 项与 乌司奴单抗生物类似药（百奥泰） 相关的临床结果
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100 项与 乌司奴单抗生物类似药（百奥泰） 相关的转化医学
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100 项与 乌司奴单抗生物类似药（百奥泰） 相关的专利（医药）
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3
项与 乌司奴单抗生物类似药（百奥泰） 相关的文献（医药）2025-12-01·JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
A phase 3, randomized, double-blind, active-controlled clinical study to compare BAT2206, a ustekinumab biosimilar, with ustekinumab reference product in patients with moderate-to-severe psoriasis: Treatment period 2 results (post Week 28 to Week 52)
Article
作者: Żebrowska, Agnieszka ; Pulka, Grażyna ; Qi, Yunpeng ; Man, Xiaoyong ; Dong, Qingfeng ; Gu, Cailing ; Yang, Xiaolei ; Deng, Yunhua ; Zheng, Min ; Mekokishvili, Lally ; Zaharieva, Katya
BACKGROUND:
BAT2206 is being developed as a ustekinumab (UST) biosimilar.
OBJECTIVES:
Equivalent efficacy and comparable safety results of BAT2206 and UST in patients with moderate-to-severe psoriasis up to Week 28 (treatment period [TP] 1) have been reported previously. TP2 (post Week 28 to 52) results are presented here.
METHODS:
Patients achieving Psoriasis Area and Severity Index response (≥75) at Week 28 entered TP2. Qualified patients of the UST group in TP1 were re-randomized 1:1 into UST-BAT2206 or UST-UST groups, while qualified patients of the BAT2206 group continued with BAT2206 (BAT2206-BAT2206 group). In TP2, secondary efficacy endpoints, pharmacokinetics, safety, and immunogenicity were assessed at Week 32, 40, 44, and 52.
RESULTS:
A total of 528 patients entered TP2, of which 133, 131, and 264 were assigned to UST-UST, UST-BAT2206, and BAT2206-BAT2206 groups, respectively. The secondary efficacy endpoints and the adverse events showed no obvious differences across all 3 groups. There were no notable differences in the UST serum concentrations. Immunogenicity was comparable, and the switching from UST to BAT2206 did not lead to an increased immunogenicity.
LIMITATIONS:
No data collected after Week 52.
CONCLUSION:
Outcomes were comparable among the groups in TP2, with no impact from the UST-to-BAT2206 switch.
2025-04-01·JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
A randomized phase III study to compare efficacy and safety of BAT2206 (proposed ustekinumab biosimilar) with reference ustekinumab in patients with moderate to severe plaque psoriasis
Article
作者: Żebrowska, Agnieszka ; Pulka, Grażyna ; Qi, Yunpeng ; Man, Xiaoyong ; Dong, Qingfeng ; Gu, Cailing ; Yang, Xiaolei ; Deng, Yunhua ; Zheng, Min ; Mekokishvili, Lally ; Zaharieva, Katya
BACKGROUND:
BAT2206 is a proposed biosimilar to reference ustekinumab (UST; Stelara).
OBJECTIVES:
To compare the efficacy and safety of BAT2206 with UST at 2 treatment periods, ie, a 28-week initial treatment period 1 (TP1) and a 24-week secondary TP2. This article describes the results of TP1.
METHODS:
In this randomized, double-blind, phase III study, adult patients with moderate to severe plaque psoriasis were randomized (1:1) to receive 45 or 90 mg of BAT2206 or UST until week 28 in TP1, depending on their baseline body weight. The primary end point was the percent change from baseline in Psoriasis Area and Severity Index score to week 8 or 12. The secondary end points included safety, pharmacokinetics, and immunogenicity parameters.
RESULTS:
In all, 278 patients were each randomized into the BAT2206 or UST groups. At weeks 8 and 12, the least squares mean difference (standard error) for percent change from baseline in Psoriasis Area and Severity Index score was 0.964 (1.8952) and 1.774 (1.4912), respectively, and the least squares mean difference confidence intervals all completely fell within the predefined equivalence margins. Comparable results were observed between the treatment groups for secondary end points.
LIMITATIONS:
Owing to the length limit, this article only described the findings from TP1.
CONCLUSIONS:
BAT2206 and UST were comparable in terms of efficacy, safety, pharmacokinetics, and immunogenicity.
2023-01-01·BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
Comparison of Pharmacokinetic Similarity, Immunogenicity, and Safety of Ustekinumab and BAT2206 in Healthy Chinese Male Subjects in a Double-Blind, Randomized, Single-Dose, Parallel-Group Phase I Trial
Article
作者: Wang, Zhaohe ; Yang, Deming ; Yang, Xiaolei ; Yang, Lizhi ; Yu, Jin-Chen ; Qi, Yunpeng ; Wang, Meng ; Wu, Min ; Mai, Jiajia ; Ding, Yanhua ; Gu, Cailing ; Li, Xiaojiao ; Li, Cuiyun ; Zhang, Hong
OBJECTIVE:
We aimed to evaluate the similarity of BAT2206 to its originator, ustekinumab, including pharmacokinetic profiles, immunogenicity, and safety in healthy Chinese male subjects.
METHODS:
This was a double-blinded, randomized, single-dose, parallel-group clinical trial, in which 270 healthy male subjects were enrolled to receive a single subcutaneous injection (45 mg) of either BAT2206 or ustekinumab (European Union or USA) at a 1:1:1 ratio. The pairwise pharmacokinetic similarities and the safety and immunogenicity of both drugs were evaluated and compared.
RESULTS:
The results showed that the 90% confidence interval of the geometric mean ratio for primary pharmacokinetic parameters (maximum plasma concentration and area under the plasma concentration-time curve from time zero to infinity) among BAT2206 and ustekinumab (USA or European Union sourced) groups were all within the predefined equivalent interval of 80-125%. Furthermore, all the groups had similar incidences of treatment-emergent adverse events, in which the majority of cases belonged to Common Terminology Criteria for the Classification of Adverse Events Grade 1 or 2. Anti-drug antibodies were detected in 54 (20.1%) subjects, namely 24 (26.7%), 13 (14.8%), and 17 (18.9%) patients in the BAT2206, ustekinumab (European Union), and ustekinumab (USA) groups, respectively. In contrast, the incidences of positive neutralizing antibodies were similar among the three groups.
CONCLUSIONS:
Pharmacokinetic similarity between BAT2206 and ustekinumab (USA or European Union sourced) was confirmed. The three groups had similar safety profiles, and the investigational drugs were well tolerated by subjects.
CLINICAL TRIAL REGISTRATION:
This study was registered with ClinicalTrials.gov (NCT04371185).
146
项与 乌司奴单抗生物类似药（百奥泰） 相关的新闻（医药）2026-01-02
·雪球
最近市场对百奥泰的关注点还在“出海”和“授权费”上，但经过我最近对公开项目资料和流出图片的交叉比对，我发现市场严重低估了这家公司的野心和执行力。这不是一家还在画饼的Biotech，而是一只正在蜕变为BigPharma的巨兽。废话不多说，直接上干货，逻辑硬核，建议收藏。一、那个“夸张”的150亿目标，可能真的不是梦新闻PPT显示：2025年：国内销售冲刺10亿（结合海外授权首付款，现金流平衡）。2026年：销售收入翻一番，正式开始盈利。2030年：全球营收目标150亿。很多人觉得150亿是吹牛，但我查阅了2025年最新的公开环评公示资料（穗开审批环评〔2025〕170号），这些枯燥的工程数据直接把百奥泰的底牌摊开了——产能已经先行落地了！二、实锤落地：二期工厂就在永和，拒绝PPT产能！之前大家还在猜“国药二期”是不是老厂扩建，现在根据项目公示位置实锤了：新二期（永和创新产业基地）是全新的地块！就在黄埔永和禾丰路以南，2025年刚确定的项目。这根本不是老厂（第一产业园）的小打小闹，而是为了支撑21万升总产能（国内前三）打造的全新核武器库。光这一期制剂线就规划了2150万支/年！按单支均价500-800元算，理论产值就是100亿+。硬件先行，说明管理层对销量有绝对信心。三、拿着显微镜看产能表：全是爆款的影子最精彩的部分来了。我仔细研究了环评报告里的《生产数量表》，百奥泰未来的管线布局早已写在数字里：1.乌司奴单抗（BAT2206）：缺席才是最大的利好！细心的朋友会发现，新二厂的表里没有乌司奴的45/90mg规格。为什么？因为二厂是制剂工厂，乌司奴原液生产必须留在“第一产业园”（老厂）生产，然后送到美国去制剂。2.贝伐珠单抗（普贝希）：真正的“压舱石”*100mg规格：独占200万瓶。*400mg大规格：与托珠单抗共享400万瓶。作为广谱抗癌药，贝伐珠单抗是典型的“大剂量、高频次”品种。这一条线就备了几百万瓶的货，说明百奥泰对贝伐在全球市场（包括美国Avzivi）的持续放量信心十足。这是公司源源不断的现金流基石。3.贝塔宁（BAT2094）：深藏不露的医保黑马产能表第一行的“20mg/瓶（多肽）”就是百奥泰唯一的1类新药——贝塔宁（倍维巴肽）。•20mg标准规格：规划年产50万瓶。•100mg大规格：规划年产50万瓶（推测为持续泵入的大包装）。合计100万瓶产能！考虑到全国每年PCI（心脏支架）手术量约160万例，这种级别的备货量只有一个解释：公司已经做好了进医保后销量井喷的准备，剑指PCI抗栓市场的半壁江山！4.阿达木单抗（格乐立）：现金牛狂奔预灌封40mg规格直接规划了400万支！这是要吃下国内集采放量+全球出口的节奏，绝对的销量王者。5.司库奇尤单抗（BAT2306）：下一个爆点表里赫然出现了150mg（成人）和75mg（儿科）各100万支的产能规划。这就是给处于NDA阶段的“可善挺”生物类似药准备的，产能先行，说明获批上市就在眼前。6.戈利木单抗（BAT2506）：自身免疫的最后一块拼图表里剩下的50mg和100mg预灌封产能（各100万支）是留给谁的？正是给戈利木单抗的！这两个规格完美对应了戈利木单抗的皮下注射剂型。随着它进入上市申报阶段，这条线将与阿达木、司库奇尤一起，构筑起百奥泰在自身免疫领域的铜墙铁壁。四、结论：预期差巨大市场还在按一家亏损Biotech给它估值，但百奥泰实际上已经做好了2026年盈利翻倍的所有准备：•创新药发力：贝塔宁（1类新药）百万产能待发，从“光脚”变“穿鞋”。•存量底气：阿达木+托珠+贝伐+乌司奴锁定全球基本盘。•增量爆发：司库奇尤+戈利木双星候场。•财务拐点：1.2亿美金首付款落袋，2025年盈亏平衡，2026年起飞。财务拐点：1.2亿美金首付款落袋，2025年盈亏平衡，2026年起飞。当一家生物药企开始拥有“国内前三”的产能时，它就不再是讲故事的初创公司，而是在印钞票的工业机器。2026年营收开始年年翻倍，2030年营收150亿。看着现在的市值，手中的筹码突然就握得更紧了。免责声明：以上内容基于公开资料及逻辑推演，不构成投资建议。股市有风险，入市需谨慎。（整理了我几个小时）
引进/卖出生物类似药临床1期
2026-01-01
·百奥泰
2026年元旦当天，广东省委书记黄坤明来到广州市深入科创企业、创新成果转化平台、假日值守保障单位等进行调研，强调广州要深入学习贯彻党的二十届四中全会和中央经济工作会议精神，全面贯彻落实习近平总书记对广东系列重要讲话和重要指示精神，按照省委十三届七次全会、八次全会暨省委经济工作会议部署，以“走在前、作示范、挑大梁”的责任担当，全力推动“十五五”开好局起好步，在关键时期的第一程展现新作为、勃发新气象。
黄坤明书记、省领导冯忠华、刘国周，广州市市长孙志洋莅临百奥泰位于广州生物岛的创新中心参观调研，走进研发实验室，参观公司的药物分析平台，详细了解该平台在辅助抗体药物发现、抗体质量研究、解析复杂分子以及数据处理合规性等方面的重要作用。黄坤明书记听取了公司关于进一步加强平台集成与标准化建设、创新药品研发及市场开拓情况的介绍，鼓励我们继续聚焦重大疾病防治需求，加大研发投入力度，高效推进临床试验、注册申报与市场准入，努力推出更多市场和群众急需的新药好药，以过硬产品赢得市场。
在调研过程中，公司相关负责人表示，我们将继续秉承“创新只为生命”的理念，持续加大研发投入，加快创新药品的研发和上市进程，为患者提供安全、有效、可负担的优质药物，以满足亟待解决的治疗需求。同时，我们也将积极响应广东省政府的号召，推动广东省生物医药产业的创新发展。
关于百奥泰
百奥泰是一家位于中国广州，基于科学而创新的全球性生物制药企业。公司致力于开发新一代创新药和生物类似药，用于治疗肿瘤、自身免疫性疾病、心血管疾病、眼科以及其它危及人类生命或健康的疾病。公司立志于成为抗体药物全球开发的领先企业，目前已推动多款药物获批上市，其中贝塔宁®（枸橼酸倍维巴肽）已在中国获批上市；阿达木单抗（英国商品名：Qletli®，中国商品名：格乐立®）已在中国及英国获批上市；托珠单抗（美国商品名：TOFIDENCE™，中国商品名：施瑞立®）已在中美欧瑞士英国五地获批上市；贝伐珠单抗（欧美商品名：Avzivi®，中国商品名：普贝希®，巴西商品名：Bevyx®）已在中美欧巴西四地获批上市；乌司奴单抗（美国商品名：STARJEMZA™，欧洲商品名：Usymro®）已在欧美获批。TOFIDENCE™成为第一个由中国药企研发、生产且获得美国FDA批准上市的单克隆抗体药物。公司另有多款候选药物进入后期临床试验，其中肿瘤领域主要聚焦后PD-1时代的肿瘤免疫治疗和抗体药物偶联体（ADC）靶向药物开发。百奥泰始终以患者的福祉作为首要核心价值，通过创新研发，为患者提供安全、有效、可负担的优质药物，以满足亟待解决的治疗需求。欲了解更多信息，请访问官网www.bio-thera.com，或关注我们的X（@bio_thera_sol）和微信公众号（百奥泰）。
百奥泰前瞻性声明
本新闻稿包含了百奥泰及产品线相关的前瞻性声明。由于某些重要因素可能会影响公司的实际结果，特此提醒读者注意不要过分依赖该前瞻性声明。这些前瞻性语句包括但不限于包含意愿、将要、可能、潜在性、预测、计划、估计、预期等类似陈述。它们都应被视为百奥泰基于截至本新闻稿发布之日可获得的信息的合理假设，并不保证未来的表现或发展。由于多种因素，实际结果和事件可能与前瞻性声明中包含的信息存在重大差异，这些因素包括但不限于本产品可能不会获得受理或批准，以及药物研究、开发和商业化中固有的风险和不确定性，例如临床前和临床研究的风险和不确定性以及能否获得药政部门的批准。其他风险因素包括生产、分销、营销、竞争、知识产权、药物功效和安全性方面的风险和不确定性，国家及全球财务与医疗状况的变化，公司财务状况的变化以及适用法律法规的变化等。本新闻稿中包含的任何前瞻性声明仅针对截止于作出声明之日的情况。除非法律要求，否则百奥泰没有义务更新本新闻稿中包含的任何前瞻性声明，以反映本新闻稿发布之日以后的新信息和事件，公司观点的改变或其他情况。
抗体药物偶联物生物类似药上市批准
2025-12-30
·肤界
2025年，国际皮肤科领域持续快速演进。越来越多来自中国的研究者，出现在British Journal of Dermatology（BJD）、Journal of the American Academy of Dermatology（JAAD）、JAMA Dermatology、JEADV、Nature、Cell等国际权威期刊的作者名单中。这些论文是中国皮肤科在全球学术体系中持续发声、深入对话的体现。
肤界编辑部对2025年中国作者发表于国际权威期刊的皮肤科研究进行了系统整理。这既是一次年度回顾，也是一份值得被保存的学术记录。它们经由时间的沉淀，最终被清晰地写进国际期刊的学术版图之中。
如果你和你的团队在这份名单中，这就是你们2025年被记录下来的一个重要注脚——
这是你2025年的一部分
也是中国皮肤科这一年共同完成的一次亮相
这一页，值得被留在2025年末的朋友圈里
2025年度BJD合集列表
（最新IF：10.6）
1.毛囊生物学中的瞬态受体电位通道：生理意义与转化相关性
Transient receptor potential channels in hair follicle biology: physiological significance and translational relevance
Hongyan Zhang , Ralf Paus , Yeqin Dai , Xiuzu Song
Br J Dermatol. 2025 Nov 18;193(6):1065-1074.
PMID: 40720581 DOI: 10.1093/bjd/ljaf295
2.NNT基因功能获得性变异导致早发性弥漫性家族性皮脂腺增生
Gain-of-function variant in NNT causes premature diffuse familial sebaceous hyperplasia
Lina Liang , Sheng Wang , Shimiao Huang , Yonghu Sun , Sha Peng , Christos C Zouboulis , Amir M Hossini , Quan Chen , Huijun Wang , Zhimiao Lin
Br J Dermatol. 2025 Nov 18;193(6):1182-1191.
PMID: 40709434 DOI: 10.1093/bjd/ljaf294
3.儿童获得性双侧Ota样斑痣：103例回顾性研究
Paediatric acquired bilateral naevus of Ota-like macules: a retrospective study of 103 cases
Wenwen Zhao , Wanting Jiang , Xing Liu , Huiying Zheng , Yiping Ge
Br J Dermatol. 2025 Nov 18;193(6):1247-1248.
PMID: 40838808 DOI: 10.1093/bjd/ljaf326
4.重复经颅磁刺激靶向右侧背外侧前额叶皮层治疗红斑毛细血管扩张性玫瑰痤疮
Repetitive transcranial magnetic stimulation targeting the right dorsolateral prefrontal cortex for the treatment of erythematotelangiectatic rosacea
Deyu Song , Hongqi Xiao , Xu Liu , Lu Zhang , Changjian Qiu , Xian Jiang
Br J Dermatol. 2025 Nov 18;193(6):1260-1262.
PMID: 40973118 DOI: 10.1093/bjd/ljaf359
5.超越基准：多模态人工智能在真实世界皮肤病学中的应用前景
Beyond benchmarks: the promise of multimodal artificial intelligence in real-world dermatology
Zhaorui Liu , Yilan Zhang , Ke Wang , Fengying Xie , Jie Liu
Br J Dermatol. 2025 Nov 18;193(6):1266.
PMID: 41105429 DOI: 10.1093/bjd/ljaf300
6.斑片状黑斑性红斑狼疮
Zonal melanotic lupus erythematosus
Yamin Zhang , Juan Tao
Br J Dermatol. 2025 Nov 18;193(6):1269.
PMID: 40581734 DOI: 10.1093/bjd/ljaf242
7.口腔浆细胞肉芽肿
Plasma cell granuloma in the oral cavity
Xiaodan Liu , Jing Su
Br J Dermatol. 2025 Nov 18;193(6):1270.
PMID: 40856410 DOI: 10.1093/bjd/ljaf325
8.臭虫所致皮肤色素沉着
Stink bug-induced cutaneous chromatosis
Ying Gu , Bin Zhang
Br J Dermatol. 2025 Nov 18;193(6):1271.
PMID: 40879461 DOI: 10.1093/bjd/ljaf336
9.葡萄酒色斑中复发性湿疹性皮炎：Meyerson现象
Recurrent eczematous dermatitis in a port-wine stain: Meyerson phenomenon
Zhen Liu , Dan-Qiong Zheng , Yi-Ming Fan
Br J Dermatol. 2025 Nov 18;193(6):1272.
PMID: 40899013 DOI: 10.1093/bjd/ljaf342
10.基于多模态数据卷积神经网络的蕈样肉芽肿及五种炎症性皮肤病的早期诊断模型
Early diagnosis model of mycosis fungoides and five inflammatory skin diseases based on a multimodal data-based convolutional neural network
Zhaorui Liu , Yilan Zhang , Ke Wang , Fengying Xie , Jie Liu
Br J Dermatol. 2025 Oct 17;193(5):968-977.
PMID: 40465821 DOI: 10.1093/bjd/ljaf212
11.化脓性汗腺炎与精神疾病：需进行细致分析
Hidradenitis suppurativa and psychiatric disease: the need for nuanced analysis
Yilin Jiang , Zhanshuo Xiao , Narina A Samah , Heng Zhou
Br J Dermatol. 2025 Oct 17;193(5):1031.
PMID: 40836439 DOI: 10.1093/bjd/ljaf328
12.胰腺胰高血糖素瘤所致坏死性游走性红斑
Necrolytic migratory erythema with a pancreatic glucagonoma
Chen-Xu Duan , Hong-Hui Xu
Br J Dermatol. 2025 Oct 17;193(5):1033-1034.
PMID: 40460242 DOI: 10.1093/bjd/ljaf216
13.小丑鼻状皮肤转移瘤
Clown nose-like cutaneous metastasis
Teng Liu , Jian-Min Chang
Br J Dermatol. 2025 Oct 17;193(5):1037.
PMID: 40554604 DOI: 10.1093/bjd/ljaf247
14.微生物组网络：皮肤健康的稳健生物标志物
Microbiome network: a robust biomarker of skin health
Xueyang Yue , Hui Wang , Yi-Ning Xu , Chung-Ching Chu , Luonan Chen
Br J Dermatol. 2025 Oct 21;193(Supplement_2):ii1-ii5.
PMID: 41118314 DOI: 10.1093/bjd/ljaf230
15.揭示痤疮微生物组特征：微生物组的作用及含植物源性单萜类成分的洁面产品配方的影响
Unveiling acne microbiome signatures: the role of the microbiome and the impact of a facewash formula containing plant-derived monoterpenes
Yi-Ning Xu , Neha Salgaonkar , Mingming Pu , Stacy Hawkins , Kevin Hermanson , Yaping Du , Chandraprabha Doraiswamy , Yimei Tan , Chao Yuan , Anindya Dasgupta , Chung-Ching Chu
Br J Dermatol. 2025 Oct 21;193(Supplement_2):ii15-ii23.
PMID: 41118315 DOI: 10.1093/bjd/ljaf287
16.皮肤微生物组作为早衰标志物：含丙酸视黄酯外用产品的增强作用
Skin microbiome as a signature of premature ageing: enhancement with a retinyl propionate-containing topical product
Yi-Ning Xu , Mingming Pu , Janhavi Raut , Yaping Du , Qiang Qiu , Kevin Hermanson , Ye Xu , Chandraprabha Doraiswamy , Chung-Ching Chu
Br J Dermatol. 2025 Oct 21;193(Supplement_2):ii24-ii31.
PMID: 40865917 DOI: 10.1093/bjd/ljaf098
17.头皮屑微生物组的鳞屑严重程度与性别差异
Dandruff scalp microbiome exhibits flake severity and sex-related differences
Bo Liang , Mingming Pu , Yi-Ning Xu , Yingjie Li , Jianing N Sun , Yuelin Zhu , Chandraprabha Doraiswamy , Tony Dadd , Chung-Ching Chu
Br J Dermatol. 2025 Oct 21;193(Supplement_2):ii32-ii39.
PMID: 41118316 DOI: 10.1093/bjd/ljaf099
18.选择性酪氨酸激酶2/Janus激酶1抑制剂TLL-018在中重度斑块型银屑病中的安全性和有效性：一项Ib期、随机、双盲、安慰剂对照研究
Safety and efficacy of the selective tyrosine kinase 2/Janus kinase 1 inhibitor TLL-018 in moderate-to-severe plaque psoriasis: a phase Ib, randomized, double-blind, placebo-controlled study
Jia-Qi Chen , Min Zheng , Wen-Hao Yin , Ping Wang , Xiao-Wei Shi , Tie-Chi Lei , Zhi-Ming Li , Meng Pan , Yu-Ling Shi , Yu-Zhen Li , Congxin Liang , Xiao-Yong Man
Br J Dermatol. 2025 Sep 18;193(4):670-677.
PMID: 40367132 DOI: 10.1093/bjd/ljaf185
19.关于“影响东亚人群头发密度的遗传与环境因素”的评论：作者回复
Comment on ‘Genetic and environmental factors affecting hair density in East Asian populations’: authors' reply
Qili Qian , Fan Liu , Sijia Wang
Br J Dermatol. 2025 Sep 18;193(4):803-804.
PMID: 40576790 DOI: 10.1093/bjd/ljaf232
20.类固醇痤疮：紫外光下荧光表现
Steroid acne: fluorescence under ultraviolet light
Lin Wang , Cheng Tan
Br J Dermatol. 2025 Sep 18;193(4):805.
PMID: 40119703 DOI: 10.1093/bjd/ljaf107
21.新生儿白血病中的蓝莓松饼样皮疹
Blueberry muffin rash in neonatal leukaemia
Zeqiao Zhang , Zhimiao Lin
Br J Dermatol. 2025 Sep 18;193(4):806.
PMID: 40139939 DOI: 10.1093/bjd/ljaf116
22.儿童砷性角膜炎
Paediatric arsenical keratosis
Xu Li , Lili Zhi
Br J Dermatol. 2025 Sep 18;193(4):808.
PMID: 40244918 DOI: 10.1093/bjd/ljaf150
23.大疱性表皮松解症中的食管狭窄：及时且全面的临床实践指南
Oesophageal strictures in epidermolysis bullosa: a timely and comprehensive clinical practice guideline
Chao-Kai Hsu , Jui-Wen Kang , Hui-Chen Su
Br J Dermatol. 2025 Aug 18;193(3):357-358.
PMID: 40570016 DOI: 10.1093/bjd/ljaf255
24.靶向MAPK通路治疗NRAS突变型黑色素瘤：从机制到临床
Targeting the MAPK pathway for NRAS mutant melanoma: from mechanism to clinic
Yi Wang , Guangchao Xu , Hongwei Xia
Br J Dermatol. 2025 Aug 18;193(3):381-393.
PMID:40341941 DOI: 10.1093/bjd/ljaf178
25.基于甲基化的良性与恶性黑色素细胞瘤诊断检测
Methylation-based test for diagnosis of benign and malignant melanocytoma
Wen-wen Zhang , Long-feng Ke , Yu Chen , Chen-yu Wu , Shu-yi Lu , Yun-li Xie , Huan-huan Zhu , Hao Chen , Gang Chen , Yan-ping Chen
Br J Dermatol. 2025 Aug 18;193(3):480-489.
PMID: 40314432 DOI: 10.1093/bjd/ljaf169
26.影响东亚人群头发密度的遗传和环境因素
Genetic and environmental factors affecting hair density in East Asian populations
Qili Qian , Yuanping Gu , Junyu Luo , Sijie Wu , Jiapeng Li , Jinxi Li , Qianqian Peng , Wenyan Chen , Yajun Yang , Jiucun Wang , Li Jin , Renliang Sun , Guoqing Zhang , Fan Liu , Sijia Wang
Br J Dermatol. 2025 Aug 18;193(3):502-513.
PMID:40251992 DOI: 10.1093/bjd/ljaf149
27.Janus激酶/信号转导和转录激活因子信号通路参与大疱性类天疱疮的免疫机制
Janus kinase/signal transducer and activator of transcription signalling pathway is involved in the immune mechanism of bullous pemphigoid
Hsin-Yu Chung , Chun-Bing Chen , Hua-En Lee , Chun-Wei Lu , Wei-Ti Chen , Rosaline Chung-Yee Hui , Min-Hui Chi , Ya-Ching Chang , Pei-Chi Lo , Chuang-Wei Wang , Wen-Hung Chung
Br J Dermatol. 2025 Aug 18;193(3):521-531.
PMID: 40577521 DOI: 10.1093/bjd/ljaf219
28.绝经年龄、激素治疗与银屑病风险：一项采用逆概率治疗加权分析的前瞻性队列研究
Menopausal age, hormone therapy and risk of psoriasis: a prospective cohort study applying inverse probability of treatment weighting analysis
Hui Xiao , Yinghe Ding , Minxue Shen , Xiang Chen , Yi Xiao
Br J Dermatol. 2025 Aug 18;193(3):570-572.
PMID: 40493749 DOI: 10.1093/bjd/ljaf222
29.新型选择性脯氨酰-tRNA合成酶抑制剂在瘢痕疙瘩治疗中的开发与评估：前景与挑战
Development and evaluation of novel and selective prolyl-tRNA synthetase inhibitor for keloid treatment: prospects and challenges
Weimin Gao , Yihua Chen
Br J Dermatol. 2025 Jul 17;193(2):201-202.
PMID: 40275445 DOI: 10.1093/bjd/ljaf161
30.激素治疗与育龄期及绝经后女性银屑病风险增加：一项全国性队列研究及靶向试验模拟
Hormone therapy and increased risk of psoriasis in reproductive-age and postmenopausal women: a nationwide cohort study and target trial emulation
Hui-Wen Yang , Yi-Hsien Chen , Sheng-Yin To , Yuan-Liang Wen , Senyeong Kao , Liang-Hsuan Chen , Li-Ting Kao
Br J Dermatol. 2025 Jul 17;193(2):259-266.
PMID: 40343984 DOI: 10.1093/bjd/ljaf179
31.白细胞介素（IL）-34促进产生IL-1β的髓系细胞在天疱疮皮损中的炎症作用
Interleukin (IL)-34 promotes the inflammatory role of IL-1β-producing myeloid cells in pemphigus lesions
Zixuan Huang , Wenzhe Zhao , Chuqiao Xu , Jie Zheng , Chuanxin Huang , Haiqin Zhu , Meng Pan
Br J Dermatol. 2025 Jul 17;193(2):287-297.
PMID: 40203120 DOI: 10.1093/bjd/ljaf130
32.扁桃体微生物群改变通过偏移衰老中性粒细胞参与银屑病免疫应答
Tonsillar microbiota alterations contribute to immune responses in psoriasis by skewing aged neutrophils
Jiaoling Chen , Xuan Liu , Yaxing Bai , Xin Tang , Ke Xue , Zhenlai Zhu , Wanting Liu , Jiaqi Wang , Caiyu Wang , Hongjiang Qiao
Br J Dermatol. 2025 Jul 17;193(2):310-321.
PMID: 40228816 DOI: 10.1093/bjd/ljaf134
33.提升英国皮肤科医师协会现行指南制定过程的透明度
Enhance the transparency in the development of the British Association of Dermatologists’ living guidelines
Hui Liu , Yuanyuan Yao , Yaolong Chen
Br J Dermatol. 2025 Jul 17;193(2):348-349.
PMID: 40172044 DOI: 10.1093/bjd/ljaf124
34.汗疱病的纽扣孔征
Buttonhole sign in anetoderma
Yu-Ting Tsai , Shang-Hung Lin
Br J Dermatol. 2025 Jul 17;193(2):352.
PMID: 39715343 DOI: 10.1093/bjd/ljae510
35.病因不常见的典型黄色荨麻疹
Typical yellow urticaria with uncommon cause
Hong-Kai Gao , Lin Wang , Cheng Tan
Br J Dermatol. 2025 Jul 17;193(2):353.
PMID: 39761338 DOI: 10.1093/bjd/ljaf002
36.肛周黑变病
Perianal melanosis
Xiya Zhao , Junqin Li
Br J Dermatol. 2025 Jul 17;193(2):354.
PMID: 39792914 DOI: 10.1093/bjd/ljaf009
37.钠-葡萄糖协同转运蛋白2抑制剂与糖尿病患者队列中新发特应性皮炎风险的负相关：一项全国性主动对照研究
Sodium–glucose cotransporter 2 inhibitors and inverse risk of new-onset atopic dermatitis in a cohort with diabetes: a nationwide active-comparator study
Yuan-Liang Wen , Wan-Ting Hsu , Yi-Hsien Chen , Hui-Han Kao , Chun-Cheng Liao , Sheng-Yin To , Hui-Wen Yang , Li-Ting Kao
Br J Dermatol. 2025 Jun 20;193(1):74-84.
PMID: 40037684 DOI: 10.1093/bjd/ljaf086
38.生物制剂治疗银屑病患者发生带状疱疹及带状疱疹后神经痛的风险：一项采用目标试验模拟框架的全国性研究
Risk of herpes zoster and postherpetic neuralgia in patients with psoriasis treated with biologics: a nationwide study using a target trial emulation framework
Chaw-Ning Lee , Miyuki Hsing-Chun Hsieh , Che-Yu Chen , Chao-Chun Yang , Tzu-Chi Liao , Edward Chia-Cheng Lai
Br J Dermatol. 2025 Jun 20;193(1):105-114.
PMID: 40112174 DOI: 10.1093/bjd/ljaf101
39.影响KLF4基因第441位天冬氨酸残基的变异可导致常染色体显性遗传综合征性鱼鳞病
Variants in KLF4 affecting residue Asp441 cause an autosomal dominant syndromic ichthyosis
Zijuan Wang , Jun Liu , Oded Wechsberg , Lina Liang , Catherine E Keegan , Christina Sloan-Heggen , You Mo , Yangyang Luo , Huijun Wang , Zhimiao Lin
Br J Dermatol. 2025 Jun 20;193(1):136-146.
PMID: 39969530 DOI: 10.1093/bjd/ljaf062
40.外显子组与转录组分析揭示钙通道通路异常与Hailey-Hailey病中A型肉毒毒素耐药性的关联
Exome and transcriptome analysis link calcium channel pathway aberrations to botulinum toxin A resistance in Hailey-Hailey disease
Yongyong Yuan , Hailun Wang , Meng Pan , Jie Zheng , Li Zhang , Han Cao , Xiaoying Chen , Yan Yang
Br J Dermatol. 2025 Jun 20;193(1):147-156.
PMID: 40317184 DOI: 10.1093/bjd/ljaf112
41.Schimmelpenning–Feuerstein–Mims综合征中的FGFR2变异
FGFR2 variants in Schimmelpenning–Feuerstein–Mims syndrome
Yixin Wang , Lingyun Zhao , Yuling Chen , Lingyu Pan , Nan Huang , Runke Zhou , Li Li
Br J Dermatol. 2025 Jun 20;193(1):167-169.
PMID: 39823306 DOI: 10.1093/bjd/ljaf025
42.二甲双胍治疗卡波西肉瘤的快速改善：两例报告
Rapid improvements in Kaposi sarcoma with metformin: a report of two cases
Ting Su , Yongkai Yu , Zhonglan Su , Yan Lu
Br J Dermatol. 2025 Jun 20;193(1):175-176.
PMID: 40067856 DOI: 10.1093/bjd/ljaf090
43.乌帕替尼在恢复特应性皮炎真菌微生物组方面优于度普利尤单抗
Upadacitinib outperforms dupilumab in restoring the fungal microbiome in atopic dermatitis
Tingting Li , Rong Tao , Li Yang , Zhe Wan , Ruoyu Li , Ruojun Wang
Br J Dermatol. 2025 Jun 20;193(1):176-178.
PMID: 40073212 DOI: 10.1093/bjd/ljaf095
44.线状窄带状黑素细胞增多症：先天性角化不良的镶嵌样表现？
Linear hypermelanosis in narrow bands: a mosaic pattern manifestation of dyskeratosis congenita?
Ran Mo , Mingming Xu , Zhiming Chen , Ruiyu Xiang , Xiaofang Li , Hongyang Li , Guoyi Zhang , Jianfang Sun , Wei Zhang , Yong Yang
Br J Dermatol. 2025 Jun 20;193(1):178-180.
PMID: 40067849 DOI: 10.1093/bjd/ljaf091
45.乳头和/或乳晕的痣样角化过度
Naevoid hyperkeratosis of the nipple and/or areola
Lin Zheng , Jingzhu Bai , Ruihua Fang
Br J Dermatol. 2025 Jun 20;193(1):190.
PMID: 39705500 DOI: 10.1093/bjd/ljae501
46.多发性骨髓瘤的舌淀粉样变性
Amyloidosis of the tongue in multiple myeloma
Yong-Wei Fu
Br J Dermatol. 2025 Jun 20;193(1):193.
PMID: 39715337 DOI: 10.1093/bjd/ljae512
47.皮肤疾病中N-6-甲基腺苷RNA甲基化的研究进展
The landscape of N 6-methyladenosine RNA methylation in skin diseases
Qi Zhang , Guozhen Liu , Li Jing , Sis Aghayants , Fangjing Xu , Yucheng Fan
Br J Dermatol. 2025 May 19;192(6):983-994.
PMID: 40059697 DOI: 10.1093/bjd/ljaf087
48.细颗粒物暴露与特应性皮炎发病率：一项出生队列研究
Fine particulate matter exposure and incident atopic dermatitis: a birth cohort study
Lih-Hwa Lin , Chung-Chin Lee , Meng-Min Hwang , Chau-Ren Jung , I Hsiu Lai , Wei-Ting Chen , Bing-Fang Hwang
Br J Dermatol. 2025 May 19;192(6):1038-1046.
PMID: 40036225 DOI: 10.1093/bjd/ljaf075
49.抗真菌药物耐药性短柄镰刀菌引起的透明丝孢霉病在CARD9缺陷患者中的发生
Hyalohyphomycosis caused by antifungal-resistant Scopulariopsis brevicaulis in a patient with CARD9 deficiency
Yanyang Guo , Tianshuo Zhao , Chunying Xiao , Dong Yan , Luming Hai , Yubo Ma , Meng Fu
Br J Dermatol. 2025 May 19;192(6):1131-1132.
PMID: 40036705 DOI: 10.1093/bjd/ljaf051
50.全球皮肤及皮下组织疾病负担：2021年全球疾病负担研究更新
Global burden of skin and subcutaneous diseases: an update from the Global Burden of Disease Study 2021
Pengcheng Huai , Peiye Xing , Yilin Yang , Yaoyao Kong , Furen Zhang
Br J Dermatol. 2025 May 19;192(6):1136-1138.
PMID: 40213811 DOI: 10.1093/bjd/ljaf071
51.Janus激酶抑制剂联合光疗治疗白癜风疗效预测生物标志物的血浆和尿液蛋白质组学分析
Proteomic analysis of plasma and urine for efficacy prediction biomarkers of Janus kinase inhibitors combined with phototherapy in vitiligo
Zhonghui Hu , Shiyu Zhang , Lu Yang , Lu Lu , Jindi Feng , Huimin He , Jianqiang Wu , Li Wen , Yuehua Liu , Tao Wang
Br J Dermatol. 2025 May 19;192(6):1141-1143.
PMID: 40036331 DOI: 10.1093/bjd/ljaf079
52.关于“化脓性汗腺炎患者中非感染性葡萄膜炎发生率”的评论
Comment on ‘Incidence of noninfectious uveitis among patients with hidradenitis suppurativa‘
Alan Y Hsu , Chun-Ju Lin , Ning-Yi Hsia , Chun-Ting Lai , Yi-Yu Tsai
Br J Dermatol. 2025 May 19;192(6):1145.
PMID: 40036876 DOI: 10.1093/bjd/ljaf083
53.全身性肉芽肿性松弛皮肤
Generalized granulomatous slack skin
Zirui Chen , Yang Wang , Ruojun Wang
Br J Dermatol. 2025 May 19;192(6):1148.
PMID: 39719156 DOI: 10.1093/bjd/ljae508
54.红斑性天疱疮的创伤性Koebner现象
Trauma-induced Koebner phenomenon in pemphigus erythematosus
Junyou Zheng , Lu Gan
Br J Dermatol. 2025 May 19;192(6):1149.
PMID: 39761812 DOI: 10.1093/bjd/ljae506
55.SLURP1疾病谱的扩展：从Meleda角化病到掌跖角化病/进行性对称性红斑角化病
Expanding the SLURP1 disease spectrum: from Mal de Meleda to palmoplantar keratoderma/progressive symmetric erythrokeratoderma
Takuya Takeichi , Chao-Kai Hsu
Br J Dermatol. 2025 Apr 28;192(5):793.
PMID: 39953724 DOI: 10.1093/bjd/ljaf059
56.调节性T细胞在白癜风免疫发病机制中的新作用及其治疗意义
Emerging role of regulatory T cells in the immunopathogenesis of vitiligo and implications for treatment
Yang Liu , Ziqi Liu , Dan Li , Xuanxuan He , Leihong Xiang , Bin Li , Chengfeng Zhang
Br J Dermatol. 2025 Apr 28;192(5):796-806.
PMID: 39673777 DOI: 10.1093/bjd/ljae472
57.泰它西普在寻常型天疱疮患者中的应用探索
Exploring telitacicept in a patient with pemphigus vulgaris
Quanhong Zhang , Jun Zhang , Bintao Su , Ruili Jiang , Lang Yu , Liuqing Chen , Jinbo Chen
Br J Dermatol. 2025 Apr 28;192(5):955-957.
PMID: 39820725 DOI: 10.1093/bjd/ljaf023
58.起源于鳞状细胞癌的扁平苔藓
Squamous cell carcinoma arising from lichen planus
Jiang-Wei Cheng , Jiu-Hong Li
Br J Dermatol. 2025 Apr 28;192(5):959.
PMID: 39761693 DOI: 10.1093/bjd/ljaf007
59.面部线状结节：一例面部淋巴皮肤孢子丝菌病
Linear nodules on the face: a case of facial lymphocutaneous sporotrichosis
Xingyu Li , Dong-Lai Ma
Br J Dermatol. 2025 Apr 28;192(5):960.
PMID: 39761691 DOI: 10.1093/bjd/ljaf010
60.乳腺外佩吉特病
Extramammary Paget disease
Ji-Bin Zhang , Qiao-Xi Li , Hao Guo
Br J Dermatol. 2025 Apr 28;192(5):961.
PMID: 39715349 DOI: 10.1093/bjd/ljae509
61.人类长毛发的进化
Evolution of long scalp hair in humans
Lo-Yu Chang , Maksim V Plikus , Nina G Jablonski , Sung-Jan Lin
Br J Dermatol. 2025 Mar 18;192(4):574-584.
PMID: 39841178
PMCID: PMC11918595
DOI: 10.1093/bjd/ljae456
62.多转录组分析揭示寻常型银屑病乳头真皮中的基质细胞促进血管生成
Multitranscriptome analysis reveals stromal cells in the papillary dermis to promote angiogenesis in psoriasis vulgaris
Bo Zhang , Junpu Mei , Qijun Liao , Shan Zhou , He Huang , Hui Liu , Xiaoli Xu , Yafen Yu , Chao Wu , Wenjun Wang , Weining Hu , Tingting Zhu , Yin Zhang , Mengyun Chen , Caihong Zhu , Mengjun Yu , Jinping Gao , Xianfa Tang , Xiawei Liu , Ze Guo , Xiaodong Zheng , Wen Zhuang , Gang Chen , Lili Tang , Xiaoyan Ding , Hui Cheng , Yang Li , Hongyan Wang , Hui Li , Yangrui Zhang , Xing Fan , Rouxi Chen , Zherou Rong , Ping Liu , Shengxiu Liu , Zhen Yue , Peiguang Wang , Zhiming Cai , Min Gao , Zaixing Wang , Xiaodong Fang , Fusheng Zhou , Huayang Tang
Br J Dermatol. 2025 Mar 18;192(4):672-683.
PMID: 39569441 DOI: 10.1093/bjd/ljae459
63.前蛋白转化酶枯草杆菌蛋白酶/kexin9型抑制剂与非黑色素瘤皮肤癌风险的关联：一项回顾性队列研究
Association of proprotein convertase subtilisin/kexin type-9 inhibitors with risk of nonmelanoma skin cancer: a retrospective cohort study
Cheng-Yuan Li , Wei-Ting Wang , Sheng-Hsiang Ma , Li-Wei Lo , Chen-Yi Wu , Wei-Chuan Chang , Yi-Ju Chen , Tai-Li Chen
Br J Dermatol. 2025 Mar 18;192(4):697-705.
PMID: 39585798 DOI: 10.1093/bjd/ljae438
64.核糖体蛋白L36介导的microRNA-4432选择性装载至细胞外囊泡中，导致静脉畸形中血管周围细胞功能障碍
Ribosomal protein L36-mediated selective loading of microRNA-4432 into extracellular vesicles contributes to perivascular cell dysfunction in venous malformations
Gao-Hong Chen , Jian-Gang Ren , Hou-Fu Xia , He-Jing Zhang , Kui-Ming Wang , Lin-Zhou Zhang , Gang Chen
Br J Dermatol. 2025 Mar 18;192(4):717-727.
PMID: 39700429 DOI: 10.1093/bjd/ljae492
65.辛伐他汀复方软膏对羊毛甾醇合酶（LSS）基因变异所致掌跖角化病的有效治疗
Effective therapy with simvastatin compound ointment in palmoplantar keratoderma induced by lanosterol synthase (LSS) gene variants
Yumeng Wang , Anqi Zhao , Haisheng Huang , Yujuan Zhai , Yeqiang Liu , Yifan Yang , Chaolan Pan , Qiaoyu Cao , Wei He , Qin Zeng , Qin Yan , Min Li , Ming Li
Br J Dermatol. 2025 Mar 18;192(4):749-751.
PMID: 39549271 DOI: 10.1093/bjd/ljae451
66.乌司奴单抗对顽固性点滴型银屑病的快速持续应答：一项为期52周、双中心、单臂观察性研究
Rapid and sustained response of stubborn guttate psoriasis to ustekinumab: a 52-week, two-centre, one-arm observational study
Liuyu Chen , Minjia Tan , Tao Li , Laiqiang Zhu , Changxu Han , Leying Liu , Zhenying Zhang
Br J Dermatol. 2025 Mar 18;192(4):759-761.
PMID: 39692217 DOI: 10.1093/bjd/ljae481
67.以弥漫性紫绀性皮肤潮红为表现的类癌综合征
Carcinoid syndrome presenting as diffuse violaceous cutaneous flushing
Meiqing Chen , Lujuan Gao
Br J Dermatol. 2025 Mar 18;192(4):772-773.
PMID: 39460433 DOI: 10.1093/bjd/ljae424
68.恙虫病典型焦痂1例
A case of typical eschar in scrub typhus
Kang An , Chaoyao Guo , Shunqiang Luo
Br J Dermatol. 2025 Mar 18;192(4):774.
PMID: 39579071 DOI:10.1093/bjd/ljae461
69.足底脓疱性丘疹和红斑斑块
Serpiginous pustules and erythematous plaques on the soles of the feet
Tian Chen , Dong-Lai Ma
Br J Dermatol. 2025 Mar 18;192(4):776.
PMID: 39724315 DOI: 10.1093/bjd/ljae497
70.氘可来昔替尼（一种口服选择性变构酪氨酸激酶2抑制剂）用于中国大陆、中国台湾及韩国的中重度斑块型银屑病患者：一项III期随机临床试验
Deucravacitinib, an oral selective allosteric tyrosine kinase 2 inhibitor, in patients from China mainland, Taiwan and South Korea with moderate-to-severe plaque psoriasis: a phase III randomized clinical trial
Jianzhong Zhang , Yangfeng Ding , Ping Wang , Linfeng Li , Weili Pan , Yan Lu , Hao Cheng , Xian Jiang , Ji-Chen Ho , Shuping Guo , Leona Liu , Arkendu Chatterjee , Renata M Kisa , Subhashis Banerjee
Br J Dermatol. 2025 Feb 18;192(3):402-409.
PMID: 39437312 DOI: 10.1093/bjd/ljae406
71.多种空气污染物的联合暴露、遗传风险与银屑病发病：一项大规模前瞻性队列研究
Joint exposure to multiple air pollutants, genetic risk and incident psoriasis: a large-scale prospective cohort study
Yan Xiong , Yuting Xia , Xinyue Zhang , Biling Jiang , Zeling Zhang , Chunhui Xie , Xiaoping Miao , Jiajia Lan , Juan Tao
Br J Dermatol. 2025 Feb 18;192(3):420-429.
PMID: 39395185 DOI: 10.1093/bjd/ljae391
72.环状RNA circASH1L（4,5）在人类皮肤伤口愈合过程中保护microRNA-129-5p免受靶向microRNA降解
Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing
Qizhang Wang , Guanglin Niu , Zhuang Liu , Maria A Toma , Jennifer Geara , Xiaowei Bian , Letian Zhang , Minna Piipponen , Dongqing Li , Aoxue Wang , Pehr Sommar , Ning Xu Landén
Br J Dermatol. 2025 Feb 18;192(3):468-480.
PMID: 39422230 DOI: 10.1093/bjd/ljae405
73.瘢痕疙瘩中机械力作用下的成纤维细胞-免疫细胞相互作用
Fibroblast-immune crosstalk under mechanical forces in keloids
Junxian Wen , Yingrou Tan , Yong Yao Chun , Timothy T Y Tan , Hong Liang Tey
Br J Dermatol. 2025 Feb 18;192(3):556.
PMID: 39547666 DOI: 10.1093/bjd/ljae449
74.腋毛癣
Trichomycosis axillaris
Fangfang Bao , Shufen Wang , Chenchen Chen , Yong Zhang , Jianke Li , Xinzhou Liu , Furen ZhangBr J Dermatol. 2025 Feb 18;192(3):557.
PMID: 39403947 DOI: 10.1093/bjd/ljae397
75.原发性皮肤曲霉感染
Primary cutaneous Alternaria alstroemeriae infection
Ximing Yang , Li Li , Min Zhu
Br J Dermatol. 2025 Feb 18;192(3):558.
PMID: 39441023 DOI: 10.1093/bjd/ljae409
76.趾甲下幼年黄色肉芽肿：一种罕见的定位
Juvenile xanthogranuloma underneath a toenail: an unusual localization
Xiaoting Song , Hang Li , Shuxia Yang
Br J Dermatol. 2025 Feb 18;192(3):559.
PMID: 39513686 DOI: 10.1093/bjd/ljae421
77.局部使用辛伐他汀-胆固醇软膏治疗掌跖角化病-先天性脱发2型的疗效改善
Improvement in palmoplantar keratoderma–congenital alopecia type 2 treated with topical simvastatin–cholesterol ointment
Fang Yang , Wanting Luo , Huijun Wang , Qian Li , Shuanghai Hu , Zhimiao Lin
Br J Dermatol. 2025 Feb 18;192(3):560-561.
PMID: 39449648 DOI: 10.1093/bjd/ljae423
78.1990至2021年10-24岁青少年及年轻成人寻常痤疮的全球、区域及国家负担：趋势分析
Global, regional and national burdens of acne vulgaris in adolescents and young adults aged 10–24 years from 1990 to 2021: a trend analysis
Zhou Zhu , Xiaoying Zhong , Zhongyu Luo , Mingjuan Liu , Hanlin Zhang , Heyi Zheng , Jun Li
Br J Dermatol. 2025 Jan 24;192(2):228-237.
PMID: 39271178 DOI: 10.1093/bjd/ljae352
79.CCR8/CCL1与CXCR3/CXCL10轴介导的难治性药物超敏反应患者记忆T细胞活化
CCR8/CCL1 and CXCR3/CXCL10 axis-mediated memory T-cell activation in patients with recalcitrant drug-induced hypersensitivity
Tsu-Man Chiu , Chun-Bing Chen , Chun-Wei Lu , Rosaline Chung-Yee Hui , Min-Hui Chi , Ya-Ching Chang , Jennifer Wu , Kuan-Yu Chen , Yang Yu-Wei Lin , Pei-Chi Lo , Tsai-Ching Hsu , Chuang-Wei Wang , Wen-Hung Chung
Br J Dermatol. 2025 Jan 24;192(2):293-305.
PMID: 39503255 DOI: 10.1093/bjd/ljae375
80.先天性全身性多毛症中的8号染色体倒位突变：精确断点定位
Chromosome 8 inversion mutation in congenital generalized hypertrichosis: localization of precise breakpoints
Anqi Zhao , Qiaoyu Cao , Chaolan Pan , Xiaoxiao Wang , Yumeng Wang , Ming Li
Br J Dermatol. 2025 Jan 24;192(2):355-357.
PMID: 39382148 DOI: 10.1093/bjd/ljae383
81.生物制剂与小分子抑制剂治疗生殖器银屑病的疗效与安全性：随机对照试验的系统评价
Efficacy and safety of biologics and small-molecule inhibitors in treating genital psoriasis: a systematic review of randomized controlled trials
Chien-Cheng Lai , Shih-Chieh Shao , Ethan T K Tsai , Ching-Chi Chi
Br J Dermatol. 2025 Jan 24;192(2):357-359.
PMID: 39344069 DOI: 10.1093/bjd/ljae370
2025年度JAAD合集列表
（最新IF：11.8）
1.麻风
Leprosy
Yin Yu, Sheng Zhong, Qiao Liu, Lin Feng
J Am Acad Dermatol. 2025 Dec;93(6):1647-1660.
PMID: 40618928 DOI: 10.1016/j.jaad.2025.06.073
2.特应性皮炎患者癌症风险与死亡率增加：来自美国国家健康与营养调查的证据
Increased cancer risk and mortality in individuals with atopic dermatitis: Evidence from the National Health and Nutrition Examination Survey
Jiliang Lu, Yufei Wang, Chaojing Zhou, Lingquan Deng, Ziyue Diao, Zhiqiang Yin
J Am Acad Dermatol. 2025 Dec;93(6):1640-1642.
PMID: 40902651 DOI: 10.1016/j.jaad.2025.08.090
3.肌炎前瞻性登记研究（PROMIS）：II.特发性炎症性肌病患者死亡原因的时间变化
The Prospective Registry Of MyositIS (PROMIS): II. Temporal shifts in causes of death among patients with idiopathic inflammatory myopathies
Chen Yu, Chanyuan Wu, Shangyi Jin, Liying Peng, Xinwang Duan, Pinting Yang, Wei Wei, Yanhong Wang, Mucong Li, Shuang Zhou, Shengyun Liu, Jing Wang, Hongbin Li, Zhaohui Zheng, Xiaofei Shi, Jian Xu, Yongfu Wang, Jiuliang Zhao, Dong Xu, Peng Yin, Xiaofeng Zeng, Mengtao Li, Qian Wang
J Am Acad Dermatol. 2025 Dec;93(6):1422-1431.
PMID: 40653049 DOI: 10.1016/j.jaad.2025.06.062
4.一项3期、随机、双盲、活性对照临床研究，旨在比较BAT2206（乌司奴单抗生物类似药）与乌司奴单抗参比制剂在中重度银屑病患者中的疗效：治疗期2结果（第28周后至第52周）
A phase, randomized, double-blind, active-controlled clinical study to compare BAT2206, a ustekinumab biosimilar, with ustekinumab reference product in patients with moderate-to-severe psoriasis: Treatment period 2 results (post Week 28 to Week 52)
Xiaoyong Man, Katya Zaharieva, Grażyna Pulka, Agnieszka Żebrowska, Yunhua Deng, Lally Mekokishvili, Xiaolei Yang, Yunpeng Qi, Cailing Gu, Qingfeng Dong, Min Zheng
J Am Acad Dermatol. 2025 Dec;93(6):1448-1455.
PMID: 40784561 DOI: 10.1016/j.jaad.2025.08.005
5.基于FAERS数据库对Janus激酶抑制剂治疗患者认知与沟通障碍不良事件信号的现实世界分析
A real-world analysis of adverse event signals of cognitive and communication disorder in patients treated with Janus kinase inhibitors based on the FAERS database
Jieyu Lin, Yufan Cheng, Ling Chen, Ming Chen, Zhu Shen
J Am Acad Dermatol. 2025 Dec;93(6):1562-1564.
PMID: 40783117 DOI: 10.1016/j.jaad.2025.08.003
6.接受度普利尤单抗治疗的特应性皮炎患儿线性生长受限风险降低：一项队列研究
Decreased risk of reduced linear growth among children with atopic dermatitis receiving dupilumab: A cohort study
Tai-Li Chen, Sheng-Hsiang Ma, Wei-Fan Ou, Chih-Chiang Chen, Chen-Yi Wu
J Am Acad Dermatol. 2025 Dec;93(6):1471-1480.
PMID: 40835132 DOI: 10.1016/j.jaad.2025.08.020
7.外用米诺地尔诱发雄激素性脱发患者毛发暂时性增多的监测与评估：一项多中心前瞻性队列研究
Monitoring and evaluation of temporary increase in hair shedding induced by topical minoxidil in androgenetic alopecia: A multicenter prospective cohort study
Yujing Zhang, Lingxia Wu, Wei Zhao, Xiangqian Li, Jianzhong Zhang, Yuanyuan Li, Cheng Zhou
J Am Acad Dermatol. 2025 Dec;93(6):1602-1604.
PMID: 40835129 DOI: 10.1016/j.jaad.2025.08.025
8.结节性痒疹患者中的重性抑郁障碍、双相情感障碍与精神分裂症：一项源自TriNetX研究网络的多中心回顾性队列研究
Major depressive disorder, bipolar disorder, and schizophrenia in patients with prurigo nodularis: A multicenter retrospective cohort study derived from TriNetX research network
Hui-Chin Chang, Tsung-Hsuan Hung, Shao-Wei Lo, Yasue Mitsukura, Shiu-Jau Chen, Shuo-Yan Gau
J Am Acad Dermatol. 2025 Dec;93(6):1606-1609.
PMID: 40846235 DOI: 10.1016/j.jaad.2025.08.028
9.成人起病的Still病持续性瘙痒性皮疹的低U型颈分布：一项包含65例患者的回顾性队列研究
Low U-neck distribution of persistent pruritic eruptions in adult-onset Still disease: A retrospective cohort study with 65 patients
Changyi Yang, Zile Chen, Yihe Zheng, Xinyue Zhong, Shuni Ying, Hong Fang, Qiancheng Deng, Jianjun Qiao
J Am Acad Dermatol. 2025 Dec;93(6):1551-1553.
PMID: 40754216 DOI: 10.1016/j.jaad.2025.07.059
10.佩索利单抗治疗泛发性脓疱型银屑病及脓疱型银屑病12周疗效：一项来自中国的前瞻性队列研究
Outcomes of spesolimab treatment of generalized pustular psoriasis and psoriasis with pustules for 12 weeks: A prospective cohort study from China
Jinru Tang, Panpan Liu, Minjia Tan, Kun Hu, Youcong Wang, Qianzi Liu, Lihong Chen, Jie Zheng, Xia Li, Yehong Kuang
J Am Acad Dermatol. 2025 Dec;93(6):1626-1628.
PMID: 40854499 DOI: 10.1016/j.jaad.2025.08.053
11.对Fakult等人《美国默克尔细胞癌流行病学》的评论
Comments on Fakult et al's "Epidemiology of Merkel cell carcinoma in the United States"
Kai-Lun Sheu, Chun-Chieh Chen, Shiuan-Chih Chen
J Am Acad Dermatol. 2025 Dec;93(6):e227-e228.
PMID: 40854500 DOI: 10.1016/j.jaad.2025.06.080
12.755nm皮秒亚历山大石激光治疗大田痣的疗效及不良反应：一项分部位、单盲、随机对照比较研究
The efficacy and adverse reactions of 755 nm picosecond alexandrite laser on the treatment of nevus of Ota at different endpoints: A split-lesion, single-blinded, randomized controlled comparison study
Xiaojin Wu, Luyu Li, Xianglei Wu, Ying Shang, Xue Wang, Zhen Zhang
J Am Acad Dermatol. 2025 Dec;93(6):1481-1488.
PMID: 40846236 DOI: 10.1016/j.jaad.2025.08.029
13.关于“早期使用羟氯喹治疗皮肤红斑狼疮以防止进展为系统性红斑狼疮：一项长期随访研究”的评论
Comment on "early initiation of hydroxychloroquine in cutaneous lupus erythematosus to prevent progression to systemic lupus erythematosus: A long-term follow-up study"
Jundong Huang, Wei Shi
J Am Acad Dermatol. 2025 Dec;93(6):e235.
PMID: 40886843 DOI: 10.1016/j.jaad.2025.04.092
14.甲基基质移植术治疗儿童指甲纵向黑色甲（>3mm）：7例病例系列评估
Toenail matrix graft reconstruction for pediatric fingernail longitudinal melanonychia > 3 mm: Evaluation of the method in a series of 7 cases
Rong Zhou, Xiaofei Tian, Lin Qiu, Xionghui Ding, Yan Liu, Jun Xiao
J Am Acad Dermatol. 2025 Dec;93(6):1564-1566.
PMID: 40784565 DOI: 10.1016/j.jaad.2025.08.004
15.对Pavlović的回应：“对Li等人‘富血小板血浆联合微针与局部米诺地尔治疗难治性重度雄激素性脱发的疗效’的回应”
Response to Pavlović's "Response to Li et al.'s 'Therapeutic efficacy of platelet-rich plasma combining with microneedling and topical minoxidil in refractory severe androgenic alopecia'"
Yanhua Li, Yizhou Wang, Yuqian Li, Xiaoqin Jia, Xufeng Du
J Am Acad Dermatol. 2025 Dec;93(6):e233-e234.
PMID: 40865726 DOI: 10.1016/j.jaad.2025.08.056
16.对Goleva等人的回应：“对Chang等人‘阿布昔替尼对比度普利尤单抗：特应性皮炎中皮肤屏障功能与蛋白质组学的影响’的回应”
Response to Goleva et al, "Response to Chang et al's 'Abrocitinib versus dupilumab: Impact on skin barrier function and proteomics in atopic dermatitis'"
Jui-Wen Chang, Fang Wang
J Am Acad Dermatol. 2025 Dec;93(6):e221-e223.
PMID: 40783116 DOI: 10.1016/j.jaad.2025.07.063
17.对Quitterie Murat de Montai等人的回应：《干扰素-α的生物学活性与皮肤红斑狼疮疾病活动度及复发风险相关：一项184例患者的单中心研究》
Response to Quitterie Murat de Montai et al, "Interferon-a biological activity is associated with disease activity and risk of flare in cutaneous lupus erythematosus: A monocentric study of 184 patients"
Zhongyu Chen, Danqi Deng
J Am Acad Dermatol. 2025 Dec;93(6):e205.
PMID: 40706682 DOI: 10.1016/j.jaad.2025.05.1459
18.曲美替尼治疗早期颅外动静脉畸形：一项多中心、前瞻性、单臂先导研究
Trametinib treatment for early-stage extracranial arteriovenous malformations: A multicenter, prospective, single-arm pilot study
Yi Sun, Hao Gu, Bin Zhang, Xitao Yang, Mingzhe Wen, Xiong Zhao, Xiaojie Yue, Hongyu Zhang, Xindong Fan, Zigang Xu, Lixin Su, Ren Cai
J Am Acad Dermatol. 2025 Nov;93(5):1261-1267.
PMID: 40683355 DOI: 10.1016/j.jaad.2025.07.033
19.利特昔替尼治疗斑秃在不同解剖部位的真实世界疗效：潜在快速应答预测因子
Real-world efficacy of ritlecitinib in treating alopecia areata across various anatomical sites: Potential rapid response predictors
Jundong Huang, Jia Jian, Min Li, Ruxin Ji, Tian Tian, Xiaobing Liang, Zhixiang Zhao, Yan Tang, Fangfen Liu, Ji Li, Wei Shi
J Am Acad Dermatol. 2025 Nov;93(5):1236-1242.
PMID: 40669542 DOI: 10.1016/j.jaad.2025.07.008
20.中国斑秃患者报告的经济负担：一项多中心横断面研究
Patient-reported economic burden of alopecia areata in China: A multicenter cross-sectional study
Xiangqian Li, Xufeng Du, Hengguang Zhao, Yanyun Wang, Longquan Pi, Ying Luo, Chiachia Hsu, Yijie Sun, Huixin Liu, Jianzhong Zhang, Hongxia Li, Cheng Zhou
J Am Acad Dermatol. 2025 Nov;93(5):1317-1319.
PMID: 40683354 DOI: 10.1016/j.jaad.2025.07.023
21.斑秃患者报告的心理社会影响：一项多中心横断面研究
Patient-reported psychosocial impact of alopecia areata: A multicenter cross-sectional study
Xiangqian Li, Xufeng Du, Hengguang Zhao, Yanyun Wang, Longquan Pi, Ying Luo, Chiachia Hsu, Yijie Sun, Huixin Liu, Shan Qu, Jianzhong Zhang, Hongxia Li, Cheng Zhou
J Am Acad Dermatol. 2025 Nov;93(5):1294-1296.
PMID: 40633619 DOI: 10.1016/j.jaad.2025.07.001
22.优化联合方案：异维A酸联合口服氨甲环酸治疗中重度寻常痤疮——一项随机、双盲、安慰剂对照试验
Optimized combination: Isotretinoin in conjunction with oral tranexamic acid for the treatment of moderate to severe acne vulgaris-A randomized, double-blind, placebo-controlled trial
Bingyang Xu, Jiawen Wu, Zining Xu, Yuxin Qing, Yuanqin Wang, Shuhong Ye, Biao Yu, Bin Zhao, Hong Sun, Na Wu, Yan Yang
J Am Acad Dermatol. 2025 Nov;93(5):1312-1314.
PMID: 40742339 DOI: 10.1016/j.jaad.2025.07.021
23.《激素治疗与女性银屑病风险增加》评述
Commentary on "Hormone therapy and increased risk of psoriasis in women"
Ching-Ting Ting, Brian Shiian Chen, James Cheng-Chung Wei
J Am Acad Dermatol. 2025 Nov;93(5):e197.
PMID: 40669541 DOI: 10.1016/j.jaad.2025.07.016
24.液氮治疗新策略：双棉签联合冷冻疗法
New strategy for liquid nitrogen treatment: Dual cotton swab combined cryotherapy
Hui Sun, Wei Shen, Yue-Hua Yao, Ying-Ming Ma, Hui-Qiong Nie, Hua-Jie Zhong
J Am Acad Dermatol. 2025 Nov;93(5):e171-e172.
PMID: 40659117 DOI: 10.1016/j.jaad.2025.07.012
25.采用头皮而非臀部或大腿皮肤进行白癜风移植
Using scalp instead of buttocks or thigh skin for vitiligo grafting
Ci Ren, Lingyu Dong, Jian Zhang
J Am Acad Dermatol. 2025 Nov;93(5):e175-e176.
PMID: 40354943 DOI: 10.1016/j.jaad.2025.05.1372
26.对Solak等人的回应：《关于“预处理中性粒细胞与淋巴细胞比值预测原发性黏膜黑色素瘤生存期”的回复》
Response to Solak et al., "Reply to "Pretreatment neutrophil-to-lymphocyte ratio predicts survival in primary mucosal melanoma""
Chian-Tzu Huang, Yi-Hua Liao, Jau-Yu Liau, Chia-Yu Chu, Yi-Shuan Sheen
J Am Acad Dermatol. 2025 Nov;93(5):e191-e192.
PMID: 40617542 DOI: 10.1016/j.jaad.2025.07.003
27.早期白细胞介素17抑制剂干预对银屑病疾病修饰的影响：一项回顾性队列研究
Disease modification in psoriasis through early interleukin 17 inhibitor intervention: A retrospective cohort study
Junchen Chen, Guo Zhou, Yang Sha, Jingge Xiao, Chen Chen, Wenyu Deng, Ruixuan Wang, Xiang Chen, Chengzhi Lv, Yehong Kuang
J Am Acad Dermatol. 2025 Oct;93(4):1000-1007.
PMID: 40516878 DOI: 10.1016/j.jaad.2025.06.019
28.1990年至2021年特应性皮炎的全球、区域和国家负担：基于2021年全球疾病负担研究的趋势分析
Global, regional, and national burdens of atopic dermatitis from 1990 to 2021: A trend analysis from the Global Burden of Disease Study 2021
Chen Sun, Xuan Zhang, Zheng Su, Wen-Hui Yao, Hong-Da Chen, Yue-Ping Zeng
J Am Acad Dermatol. 2025 Oct;93(4):1008-1017.
PMID: 40543661 DOI: 10.1016/j.jaad.2025.06.042
29.银屑病与雌激素的关联：一项基于人群的研究
Association between psoriasis and estrogen: A population-based study
Chenxingyue Zhang, Xinyi Dai, Zhiqiang Yin
J Am Acad Dermatol. 2025 Oct;93(4):1141-1143.
PMID: 40615094 DOI: 10.1016/j.jaad.2025.06.064
30.利特昔替尼治疗斑秃：一项多中心回顾性真实世界分析
Ritlecitinib in alopecia areata: A multicenter retrospective real-world analysis
Wenhan Zhang, Xiangqian Li, Yujing Zhang, Ying Luo, Hongxia Li, Cheng Zhou
J Am Acad Dermatol. 2025 Oct;93(4):1136-1137.
PMID: 40543667 DOI: 10.1016/j.jaad.2025.06.041
31.β受体阻滞剂与甲氨蝶呤联合治疗高血压银屑病患者的疗效关联：一项回顾性队列研究
Association of β-blockers with methotrexate efficacy in psoriasis patients with hypertension: A retrospective cohort study
Dawei Huang, Rui Ma, Suyang Lin, Jiangluyi Cai, Yu Wang, Yuxiong Jiang, Tingting Wang, Yifan Hu, Xiaoyun Xie, Jun Gu, Jinhua Xu, Xia Li, Xinling Bi, Hui Deng, Xin Li, Chunyuan Guo, Yangfeng Ding, Yuling Shi
J Am Acad Dermatol. 2025 Oct;93(4):1081-1083.
PMID: 40531068 DOI: 10.1016/j.jaad.2025.05.1431
32.重复经颅磁刺激治疗红斑毛细血管扩张型玫瑰痤疮的疗效与安全性：一项单中心、随机、双盲、假手术对照的器械试验
Efficacy and safety of repetitive transcranial magnetic stimulation in treating erythema to telangiectatic rosacea: A single-center, randomized, double-blind, sham-controlled device trial
Mingwang Zhang, Ling Ji, Mei Wan, Han Luo, Shanshan Gu, Huan Wang, Li Tang, Aiai Xia, Minmin Kong, Min Li, Jing Tian, Zhifei Pan, Jinyu Wei, Zhiqiang Song, Jian Li
J Am Acad Dermatol. 2025 Oct;93(4):1133-1135.
PMID: 40543669 DOI: 10.1016/j.jaad.2025.06.040
33.古塞奇尤单抗与乌司奴单抗治疗中重度斑块型银屑病合并潜伏性结核病或非活动性乙型肝炎病毒感染患者的安全性：一项回顾性多中心研究观察性研究
Safety of guselkumab and ustekinumab treatment in patients with moderate-to-severe plaque psoriasis combined with latent tuberculosis or inactive hepatitis B virus infection: a retrospective multicenter observational study
Wen-Sheng Lu, Jun Zhao, JianFeng Wang, Ruixue Chang
J Am Acad Dermatol. 2025 Oct;93(4):1088-1089.
PMID: 40482822 DOI: 10.1016/j.jaad.2025.06.002
34.局部使用辛伐他汀联合胆固醇乳膏对比单纯局部使用辛伐他汀乳膏治疗色素性毛囊角化病的安全性与有效性：一项随机、单盲、分体、安慰剂对照、研究者发起的试验
Safety and efficacy of topical simvastatin plus cholesterol cream versus topical simvastatin cream alone for porokeratosis ptychotropica: A randomized, single-blind, split-body, placebo-controlled, investigator-initiated trial
Zhiming Chen, Yihe Liu, Hui Yu, Jing Li, Xin Huang, Ruiyu Xiang, Ran Mo, Hao Chen, Yong Yang
J Am Acad Dermatol. 2025 Oct;93(4):980-987.
PMID: 40403974 DOI: 10.1016/j.jaad.2025.04.082
35.基于新型炎症标志物的嗜酸性粒细胞增多伴全身症状药物反应预后模型的开发与验证：一项国际多中心队列研究
Development and validation of prognostic models using novel inflammatory markers for drug reactions with eosinophilia and systemic symptoms: An international multicenter cohort study
Tyng-Shiuan Hsieh, Haur Yueh Lee, Riichiro Abe, Shingo Takei, Ryota Hayashi, Natsumi Hama, Yung-Tsu Cho, Po-Wei Huang, Chia-Yu Chu
J Am Acad Dermatol. 2025 Oct;93(4):1027-1034.
PMID: 40663026 DOI: 10.1016/j.jaad.2025.06.051
36.司库奇尤单抗与全身性皮质类固醇联合治疗急性泛发性发疹性脓疱病的疗效评估：一项回顾性队列研究
Evaluation of combination therapy with secukinumab and systemic corticosteroids for acute generalized exanthematous pustulosis: A retrospective cohort study
Xiao-Qing Lv, Shi-Fan Ruan, Jia-Wen Chen, Xin-Hong Su, Kun Qin, Xue-Ting Zeng, Li-Hong Chen, Niu Xiang, Ting Gong, Chao Ji
J Am Acad Dermatol. 2025 Oct;93(4):1075-1077.
PMID: 40419223 DOI: 10.1016/j.jaad.2025.05.1419
37.对《遗传性平滑肌瘤病与肾细胞癌综合征中皮肤平滑肌瘤诊断指标的评估：一项观察性研究》的评论
Comment on "Assessing the diagnostic metrics of cutaneous leiomyomas in hereditary leiomyomatosis and renal cell cancer syndrome: An observational study"
Mengxia Qi, Wenjie Wang, Yuxing Xie, Yani Li, Xiangying Yang
J Am Acad Dermatol. 2025 Oct;93(4):e147-e148.
PMID: 40518119 DOI: 10.1016/j.jaad.2025.05.1454
38.人乳头瘤病毒感染增加新发结节性痒疹风险：一项基于TriNetX网络全球及美国电子病历的多中心回顾性队列研究
Human papillomavirus infection increases risk of new-onset prurigo nodularis: A multicenter retrospective cohort study using global and US electronic medical records of TriNetX network
Shuo-Yan Gau, Shao-Wei Lo, Yung-Fang Tu, Wen-Chieh Liao, Yu-Jung Su, Hui-Chin Chang, Torsten Zuberbier, Martin Metz, Shiu-Jau Chen
J Am Acad Dermatol. 2025 Oct;93(4):1092-1095.
PMID: 40480370 DOI: 10.1016/j.jaad.2025.05.1442
39.评论：“Plicature与强制近似技术加速功能性指甲手术后第二期愈合，获得良好的美容与功能结局：一项前瞻性试点研究”
Comment on: "Plicature and forced approximation technique accelerates second-intention healing after functional nail surgery with favorable cosmetic and functional outcomes: A prospective pilot study"
Chongjie Zhang, Yibin Ma
J Am Acad Dermatol. 2025 Oct;93(4):e161-e162.
PMID: 40582513 DOI: 10.1016/j.jaad.2025.05.1457
40.口服厄洛替尼治疗短暂性受体电位香草酸亚型3相关Olmsted综合征的疗效与安全性：病例系列分析
Efficacy and safety of oral erlotinib in transient receptor potential vanilloid-3-related Olmsted syndrome: A case series
Xuewan Zhang, Ruzeng Xue, Zeqiao Zhang, Huijun Wang, Zhimiao Lin
J Am Acad Dermatol. 2025 Oct;93(4):1145-1147.
PMID: 40615090 DOI: 10.1016/j.jaad.2025.06.066
41.自体游离甲单位移植术改善甲基质及甲床损伤所致甲单位畸形或缺失：病例系列与文献综述
Autologous free nail unit transplantation for improving nail unit deformities or loss caused by nail matrix and nail bed injuries: A case series and literature review
Pengfei Wen, Simin He, Hongjie Liu, Siliang Xue
J Am Acad Dermatol. 2025 Oct;93(4):1065-1066.
PMID: 40268055 DOI: 10.1016/j.jaad.2025.04.033
42.对Mendoza等学者《抗高血压药物使用与光化性角化病治疗的关联：一项基于TriNetX人群的研究》的评论
Comment on Mendoza et al's "Association between use of antihypertensives and treatment of actinic keratoses: A TriNetX population-based study"
I-Chang Lai, James Cheng-Chung Wei
J Am Acad Dermatol. 2025 Oct;93(4):e157-e158.
PMID: 40602529 DOI: 10.1016/j.jaad.2025.03.105
43.木偶戏启发的悬吊技术：一种提升凹陷区皮肤病变切除手术安全性和美学效果的实用方法
Puppet theater-inspired string-hanging technique: A practical method for improving surgical safety and aesthetic outcome in the resection of skin lesions in sunken areas
Jing Yang, Yuchong Chen
J Am Acad Dermatol. 2025 Oct;93(4):e129-e130.
PMID: 40199383 DOI: 10.1016/j.jaad.2025.04.008
44.三种利妥昔单抗给药方案治疗中重度寻常型天疱疮和落叶型天疱疮的疗效、安全性及B细胞清除能力：一项为期52周的临床试验
Efficacy, safety, and B-cell depletion capacity of 3 rituximab dosing regimens in the treatment of moderate-to-severe pemphigus vulgaris and pemphigus foliaceus: A 52-week clinical trial
Shan Cao, Baoqi Yang, Zhenzhen Wang, Tingting Liu, Yonghu Sun, Zhaoxia Zhang, Futang Pan, Qing Yang, Hanqing Geng, Qing Zhao, Hong Liu, Furen Zhang
J Am Acad Dermatol. 2025 Sep;93(3):634-643.
PMID: 40374120 DOI: 10.1016/j.jaad.2025.05.1374
45.生活方式因素对银屑病患者心脏代谢共病及死亡率的影响：多状态模型分析
The impact of lifestyle factors on cardiometabolic comorbidities and mortality of psoriatic diseases: A multistate model analysis
Yi Xiao, Songchun Yang, Yang Zhang, Yixuan Tong, Danrong Jing, Yinli Zhou, Hui Xiao, Yehong Kuang, Minxue Shen, Xiang Chen
J Am Acad Dermatol. 2025 Sep;93(3):715-723.
PMID: 40383272 DOI: 10.1016/j.jaad.2025.05.1395
46.睡眠障碍在银屑病-抑郁关联中的中介作用：一项基于人群的研究
The mediating role of sleep disturbances in the psoriasis-depression association: A population-based study
Jiliang Lu, Ningning Zhang, Chaojing Zhou, Yufei Wang, Zhiqiang Yin
J Am Acad Dermatol. 2025 Sep;93(3):804-806.
PMID: 40368186 DOI: 10.1016/j.jaad.2025.05.1368
47.银屑病患者血清25-羟基维生素D浓度与死亡率及心血管疾病风险的关联
Associations of serum 25-hydroxyvitamin D concentrations with risks of mortality and cardiovascular disease among individuals with psoriasis
Kaiqing Lin, Ya Miao, Lu Gan, Bin Zhao, Fang Fang, Ru Wang, Xiang Chen, Jiaqi Huang
J Am Acad Dermatol. 2025 Sep;93(3):678-688.
PMID: 40378890 DOI: 10.1016/j.jaad.2025.05.1380
48.乌帕替尼治疗既往全身治疗无效的难治性斑秃：一项回顾性研究
Upadacitinib for refractory alopecia areata unresponsive to prior systemic therapies: A retrospective study
Qin Wang, Linxia Shen, Yuou Sha, Ke Tao, Jui-Ming Lin, Lijuan Zhou, Sisi Qi, Yue Zhang, Jinran Lin, Wenyu Wu
J Am Acad Dermatol. 2025 Sep;93(3):761-763.
PMID: 40339809 DOI: 10.1016/j.jaad.2025.04.070
49.基于FAERS数据库对不同JAK抑制剂所致血栓栓塞及心血管不良事件信号强度的不成比例性分析
A disproportionality analysis of thromboembolic and cardiovascular adverse event signal strength across various JAK-inhibitors based on the FAERS database
Xinlin Zheng, Yufan Cheng, Ling Chen, Zhu Shen
J Am Acad Dermatol. 2025 Sep;93(3):850-854.
PMID: 40419222 DOI: 10.1016/j.jaad.2025.05.1417
50.Janus激酶抑制剂在18岁及以下斑秃患者中的应用：系统评价与荟萃分析
Use of Janus kinase inhibitors in patients aged ≤18 years with alopecia areata: A systematic review and meta-analysis
Kejia Xu, Gu He, Zhongyue Deng, Lin Wang, Mao Lin
J Am Acad Dermatol. 2025 Sep;93(3):831-833.
PMID: 40383271 DOI: 10.1016/j.jaad.2025.05.1396
51.饮料摄入增加中国成年人痤疮风险：一项横断面研究
Beverage consumption increases acne risk in Chinese adults: A cross-sectional study
Shiyu He, Shaodie Yang, Yaqian Zhu, Jianping Wei, Yang Guan, Min He, Ning Ning, Jiayu He, Yanyan Li, Xiangzi Li
J Am Acad Dermatol. 2025 Sep;93(3):792-795.
PMID: 40345543 DOI: 10.1016/j.jaad.2025.04.067
52.针对类固醇难治性手足湿疹的个性化紫外线A1光疗策略：一项前瞻性研究
Personalized ultraviolet A1 phototherapy strategies for steroid-refractory hand-foot eczema: A prospective study
Yu Hu, Liangliang Zhang, Hongying Chen, Shudai Huang, Minjie Shu, Nengxin Shao, Eryan Ding, Lili Wang, Chao Luan, Jiaan Zhang, Kun Chen
J Am Acad Dermatol. 2025 Sep;93(3):820-821.
PMID: 40378887 DOI: 10.1016/j.jaad.2025.05.1381
53.系统评价中生成式人工智能应用的透明报告
Transparent reporting of generative artificial intelligence use in systematic reviews
Xufei Luo, Yaolong Chen
J Am Acad Dermatol. 2025 Sep;93(3):e117-e118.
PMID: 40446965 DOI: 10.1016/j.jaad.2025.03.101
54.致Alameddine等《乳糜泻相关斑秃：一项多中心病例对照研究》的信函
Letter to Alameddine et al's "Celiac disease associated with alopecia areata: A multicenter case-control study"
Yuwei Xu, Wenrun Hou, Jinfang Gao, James Cheng-Chung Wei, Liyun Zhang
J Am Acad Dermatol. 2025 Sep;93(3):e115-e116.
PMID: 40412724 DOI: 10.1016/j.jaad.2025.05.1405
55.对Kaltchenko等学者《度普利尤单抗与儿童特应性皮炎神经精神结局：真实世界队列分析》的评论
Comment on Kaltchenko et al's "Dupilumab and neuropsychiatric outcomes in pediatric atopic dermatitis: A real-world cohort analysis"
I-Chang Lai, James Cheng-Chung Wei
J Am Acad Dermatol. 2025 Sep;93(3):e109-e110.
PMID: 40328418 DOI: 10.1016/j.jaad.2025.02.101
56.阿布昔替尼vs.度普利尤单抗：对特应性皮炎皮肤屏障功能及蛋白质组学的影响
Abrocitinib versus dupilumab: Impact on skin barrier function and proteomics in atopic dermatitis
Jui-Wen Chang, Xiaobao Huang, Wenjing Jiang, Lerong Lun, Wenhui Liu, Rui Xu, Rui Tang, Xinyang Xie, Wanying Zhai, Huilin Su, Jiande Han, Ruzeng Xue, Fang Wang
J Am Acad Dermatol. 2025 Aug;93(2):406-414.
PMID: 40246083 DOI: 10.1016/j.jaad.2025.04.027
57.芦可替尼乳膏治疗中国非节段性白癜风的有效性与安全性
Effectiveness and safety of ruxolitinib cream in Chinese patients with nonsegmental vitiligo
He Huang, Yujun Sheng, Min Li, Xianfa Tang, Yaohua Zhang, Dawei Duan, Hequn Huang, Jurui Zhang, Weiran Li, Tingting Zhu, Huayang Tang, Yuanyuan Yin, Leihong Xiang, Xuejun Zhang, Youwen Zhou, Yong Cui, Bo Zhang
J Am Acad Dermatol. 2025 Aug;93(2):475-477.
PMID: 40286823 DOI: 10.1016/j.jaad.2025.04.041
58.1990至2021年全球银屑病负担：基于人群的分析
Global burden of psoriasis from 1990 to 2021: A population-based analysis
Jiliang Lu, Ningning Zhang, Xiaozheng Jiang, Ziyue Diao, Dandan Chen, Zhiqiang Yin
J Am Acad Dermatol. 2025 Aug;93(2):532-533.
PMID: 40203899 DOI: 10.1016/j.jaad.2025.04.012
59.口服JAK1抑制剂乌帕替尼单药治疗丘疹脓疱型玫瑰痤疮的疗效与安全性：一项真实世界研究
Efficacy and safety of oral JAK1 inhibitor upadacitinib monotherapy for papulopustular rosacea: A real-world study
Bingyang Xu, Yuxin Qing, Yuanqin Wang, Zining Xu, Shuhong Ye, Bin Zhao, Hong Sun, Na Wu, Jiawen Wu
J Am Acad Dermatol. 2025 Aug;93(2):540-542.
PMID: 40304648 DOI: 10.1016/j.jaad.2025.04.020
60.关于度普利尤单抗与特应性皮炎患者皮肤T细胞淋巴瘤潜在关联的思考
Considerations on the potential link between dupilumab and cutaneous T-cell lymphoma in atopic dermatitis
Yongli Jin
J Am Acad Dermatol. 2025 Aug;93(2):e61-e62.
PMID: 40187533 DOI: 10.1016/j.jaad.2025.02.099
61.度普利尤单抗治疗血液透析患者慢性肾脏病相关性瘙痒的疗效：一项回顾性观察研究
Efficacy of dupilumab for chronic kidney disease-associated pruritus in patients undergoing hemodialysis: Retrospective observational study
Zhiwen Wang, Chen Chen, Yu Xiong, Yingying Feng, Junchen Chen, Hui Xu
J Am Acad Dermatol. 2025 Aug;93(2):501-503.
PMID: 40158547 DOI: 10.1016/j.jaad.2025.03.067
62.遗传分类有助于慢血流血管畸形患者西罗莫司的精准治疗：一项前瞻性队列研究
Genetic classification helps with precise sirolimus treatment in slow-flow vascular malformations: A prospective cohort study
Hongyuan Liu, Yuxi Chen, Xuanfeng Chen, Shih-Jen Chang, Yamin Rao, Xi Yang, Li Hu, Zian Xu, Hao Gu, Yajing Qiu, Chen Hua, Hui Chen, Xiaoxi Lin
J Am Acad Dermatol. 2025 Aug;93(2):533-536.
PMID: 40216197 DOI: 10.1016/j.jaad.2025.04.013
63.人乳头瘤病毒基因型影响足底疣热疗疗效：一项质量改进研究
Human papillomavirus genotypes affect the efficacy of hyperthermia therapy for plantar warts: A quality improvement study
Xu Han, Hui-Feng Wang, Lei Ma, Ri-Xin Chen, Qiang Wang, Chun-Hong Zhang, Hai-Hong Zhang, Yue Han, Yang Yang, Hao Guo, Yun-Qiu Gao, Li Zhang, Hong-Wei Yan, Shuai Qiao, Yu Gao, Chun-Mei Shu, Li-Hao Pei, Hui Ma, Xiao-Dong Sun, Chun-Min Zhang, Hai-Jing Jiang, Xue-Qi Li, Ming-Ru Li, Gui-Feng Xu, Hong-Duo Chen, Rui-Qun Qi, Xing-Hua Gao
J Am Acad Dermatol. 2025 Aug;93(2):536-538.
PMID: 40216196 DOI: 10.1016/j.jaad.2025.04.015
64.泼尼松联合阿达木单抗或环孢素对Vogt-Koyanagi-Harada病皮肤症状的影响：一项随机试验的系统性结果
Effect of prednisone plus either adalimumab or cyclosporine on dermatological symptoms in Vogt-Koyanagi-Harada disease: Systemic outcomes from a randomized trial
Zhenyu Zhong, Jiayi Wang, Weiting Liao, Junjie Xiang, Tao Cai, Peizeng Yang
J Am Acad Dermatol. 2025 Aug;93(2):415-422.
PMID: 40043888 DOI: 10.1016/j.jaad.2025.02.081
65.吸烟状况对皮肤狼疮活动趋势的影响
Impact of smoking status on cutaneous lupus activity trends
Gujie Wu, Lanmei Lin, Juan Du
J Am Acad Dermatol. 2025 Aug;93(2):e87-e88.
PMID: 40286814 DOI: 10.1016/j.jaad.2025.03.095
66.二肽基肽酶-4抑制剂相关与非二肽基肽酶-4抑制剂相关大疱性类天疱疮的临床与实验室特征差异：系统评价与荟萃分析
Differences of clinical and laboratory features between dipeptidyl peptidase-4 inhibitor-related and nondipeptidyl peptidase-4 inhibitor-related bullous pemphigoid: A systematic review and meta-analysis
Yi-Hsuan Shen, Yu-Chen Huang
J Am Acad Dermatol. 2025 Aug;93(2):499-501.
PMID: 40158542 DOI: 10.1016/j.jaad.2025.02.095
67.电离子疗法治疗睑黄瘤：作为一种低复发率且具有成本效益的潜在治疗方案
Electro-ion therapy for xanthelasma palpebrarum: Potential as a low-recurrence and cost-effective treatment
Xiaowen Huang, Siqi Zheng, Keshav Raj Gyawali, Pingjiao Chen, Qian Li, Menghua Zhu, Jia Guo, Sijin He, Yue Zheng
J Am Acad Dermatol. 2025 Aug;93(2):549-551.
PMID: 40107510 DOI: 10.1016/j.jaad.2025.03.024
68.1990年至2021年全球黑色素瘤负担不平等：2021年全球疾病负担研究结果
Global inequalities in the burden of melanoma from 1990 to 2021: Findings from the Global Burden of Disease study 2021
Ziyi Han, Jialin Hou, Minjing Chang
J Am Acad Dermatol. 2025 Aug;93(2):e91-e92.
PMID: 40324531 DOI: 10.1016/j.jaad.2025.03.096
69.大面积皮肤暴露患者的简易外科换药
A simple surgical dressing change for patients with extensive skin exposure
Jinhui Xu, Qingwei Geng, Yong Hu, Zehu Liu, Xiuzu Song
J Am Acad Dermatol. 2025 Aug;93(2):e47-e48.
PMID: 39923850 DOI: 10.1016/j.jaad.2025.02.008
70.提升头皮冷却疗法的可及性：我们应如何推进？——对Novice等学者《头皮冷却疗法的经济负担：非营利组织数据分析》的回应
Enhancing access to scalp cooling therapy: How can we move forward? A response to Novice et al's "the financial burden of scalp cooling therapy: A nonprofit organization data analysis"
Mengwen He, Huimin Jia
J Am Acad Dermatol. 2025 Aug;93(2):e81.
PMID: 40288540 DOI: 10.1016/j.jaad.2025.03.093
71.关于Vera等人的研究《与未接受生物制剂治疗的银屑病患者相比，白细胞介素-23抑制剂可降低心血管危险因素相关疾病的发生率：一项回顾性队列研究》的评论
Comment on Vera et al's "Interleukin-23 inhibition associates with lower incidence of cardiovascular risk factor type diseases compared to biologic naïve patients with psoriasis: A retrospective cohort study."
I-Chang Lai, James Cheng-Chung WeiJ Am Acad Dermatol. 2025 Aug;93(2):e51-e52.
PMID: 40139318 DOI: 10.1016/j.jaad.2024.12.054
72.异维A酸使用者报告的精神科不良事件：基于20年FDA不良事件报告系统数据库研究的监测重点
Reported psychiatric adverse events among isotretinoin users: Monitoring priorities from a 20-year FDA Adverse Event Reporting System database study
Wenjia Nie, Xiaopeng Wu, Yuting Xia, Liyun Zheng, Hengcheng Lu
J Am Acad Dermatol. 2025 Jul;93(1):64-72.
PMID: 40024390 DOI: 10.1016/j.jaad.2025.02.072
73.生物制剂治疗超应答者与生物制剂难治性银屑病患者的特征及疗效：中国单中心回顾性研究
Characterization and treatment outcomes of biologic therapy in super-responders and biologic-refractory psoriasis patients: A single-center retrospective study in China
Yizhang Liu, Kun Hu, Yongfang Duan, Xiang Chen, Mi Zhang, Yehong Kuang
J Am Acad Dermatol. 2025 Jul;93(1):46-54.
PMID: 40020926 DOI: 10.1016/j.jaad.2025.02.063
74.高剂量与低剂量西罗莫司治疗卡波西样血管内皮瘤的疗效与安全性：一项随机临床试验
Efficacy and safety of high-vs low-dose sirolimus in patients with kaposiformhemangioendothelioma: A randomized clinical trial
Jiangyuan Zhou, Yuru Lan, Tong Qiu, Zixin Zhang, Xue Gong, Xuepeng Zhang, Congxia Yang, Zilong Zhou, Yujia Zhang, Min Yang, Jianlei Fu, Chunshui He, Qiang Peng, Fan Hu, Chunchao Xia, Feiteng Kong, Siyuan Chen, Yi Ji
J Am Acad Dermatol. 2025 Jul;93(1):124-131.
PMID: 40107509 DOI: 10.1016/j.jaad.2025.03.023
75.乌帕替尼治疗斑秃的临床疗效与安全性：一项回顾性研究
Clinical response and safety of upadacitinib for alopecia areata: A retrospective study
Jiecheng Li, Xiangqian Li, Yuxin Wang, Cheng Zhou
J Am Acad Dermatol. 2025 Jul;93(1):196-197.
PMID: 40043887 DOI: 10.1016/j.jaad.2025.02.083
76.SYSA1902对比参比制剂乌司奴单抗治疗中重度斑块型银屑病的疗效与安全性：一项多中心、随机、III期研究
Efficacy and safety of SYSA1902 versus reference ustekinumab in moderate-to-severe plaque psoriasis: A multicenter, randomized, phase III study
Lixin Xia, Guoying Miao, Xiumin Yang, Yumei Li, Yunsheng Liang, Yanling Li, Linfeng Li, Liping Ma, Furen Zhang, Rixin Chen, Xinsuo Duan, Lihua Wang, Yanyan Feng, Ziyan Li, Fengyan Lu, Jinyan Wang, Shuping Guo, Jiawen Zhao, Liming Wu, Yong Cui, Shanshan Li, Chao Ji, Xiaodong Li, Tiechi Lei, Juanli Fan, Xinghua Gao
J Am Acad Dermatol. 2025 Jul;93(1):115-123.
PMID: 40208132 DOI: 10.1016/j.jaad.2025.03.018
77.口服利特昔替尼治疗难治性白癜风的回顾性研究
Oral ritlecitinib for the treatment of refractory vitiligo: A retrospective study
Xiaoyi Shi, Rongsi Sun, Yukun Yuan, Juan Du, Fang Wang, Mengyi Zhu, Xiaolan Ding
J Am Acad Dermatol. 2025 Jul;93(1):206-208.
PMID: 40120817 DOI: 10.1016/j.jaad.2025.03.040
78.瘙痒症的全球、区域及国家负担：基于1992-2021年全球疾病负担的综合研究
Global, regional, and National burden of pruritus: A comprehensive study from the Global Burden of Disease, 1992-2021
Meichen Jin, Jiang Li, Jun Niu
J Am Acad Dermatol. 2025 Jul;93(1):199-202.
PMID: 40139316 DOI: 10.1016/j.jaad.2025.03.062
79.利妥昔单抗治疗与全身性皮质类固醇治疗在大疱性类天疱疮患者心血管结局中的比较：基于TriNetX数据库的倾向性匹配回顾性研究
Cardiovascular outcomes in patients with bullous pemphigoid on rituximab compared to those on systemic corticosteroids: A propensity-matched retrospective study using the TriNetX database
Renin Chang, Wen-Hwa Wang, Alisa Chen, Chia-Yu Chu, Kai-Che Wei
J Am Acad Dermatol. 2025 Jul;93(1):231-234.
PMID: 40020927 DOI: 10.1016/j.jaad.2025.02.058
80.巴瑞替尼在中度斑秃、重度斑秃、全秃及泛发性脱发中的疗效：一项真实世界对比研究
Efficacy of baricitinib in moderate alopecia areata, severe alopecia areata, alopecia totalis, and alopecia universalis: A real-world comparative study
Guan Jiang, Xinru Liu, Xuhui Jiang, Yaxin Zhang
J Am Acad Dermatol. 2025 Jul;93(1):204-206.
PMID: 40107506 DOI: 10.1016/j.jaad.2025.03.026
81.痤疮进展的两种不同模式：发病机制及治疗意义
Two distinct patterns of acne progression: Pathogenesis and implications for management
Qiuhong Xiao, Zhen Rang, Shangke Liu, Yifan Wang, Yufei Ma, Yuqi Zhang, Yu Lv, Junru Ye, Qian Wang, Wei Liu
J Am Acad Dermatol. 2025 Jul;93(1):234-237.
PMID: 40015572 DOI: 10.1016/j.jaad.2025.02.060
82.优化黑色素瘤活检操作：对临床准确性及患者预后的影响
Optimizing melanoma biopsy practices: Implications for clinical accuracy and patient outcomes
Xichen Fan, Yuxiang Zhao, Xin Zhao
J Am Acad Dermatol. 2025 Jul;93(1):e37-e38.
PMID: 40164387 DOI: 10.1016/j.jaad.2025.03.079
83.关于“度普利尤单抗与儿童特应性皮炎神经精神结局：一项真实世界队列分析”的评论
Comments on "Dupilumab and neuropsychiatric outcomes in pediatric atopic dermatitis: A real-world cohort analysis"
Rong Li, Junyan Zhang, Lei Wang, Li-Yun Zhang
J Am Acad Dermatol. 2025 Jul;93(1):e39-e40.
PMID: 40180128 DOI: 10.1016/j.jaad.2025.03.080
84.在黑色素瘤患者中，细胞毒性T淋巴细胞相关蛋白4抑制剂比程序性细胞死亡蛋白1抑制剂具有更高的心血管事件风险
Cytotoxic T-lymphocyte associated protein 4 inhibitors are associated with a higher risk of cardiovascular events than programmed cell death protein 1 inhibitors in patients with melanoma
Ching-Chung Chang, Shao-Wei Lo, Hua-Ching Chang, Junmin Song, Yu-Cheng Chang, Kevin Yang, Kuan-Yu Chi, Yu Chang, Cho-Hung Chiang, Cho-Han Chiang
J Am Acad Dermatol. 2025 Jul;93(1):202-204.
PMID: 40023406 DOI: 10.1016/j.jaad.2025.02.074
85.一种用于皮肤创面的简易负压引流装置
A simple negative pressure drainage device for skin wounds
Qiuyun Xu, Songyu Wang, Shuyi Shen, Ting Gong, Fang Fang, Chao Ji
J Am Acad Dermatol. 2025 Jul;93(1):e5-e6.
PMID: 39746616 DOI: 10.1016/j.jaad.2024.11.075
86.一种经济高效且简便的足趾蹼病变切除术可视化增强方法
A cost-effective and simple method to enhance visualization in toe-web lesion excision
Guoqun Yu, Fan Yang, Yamin Zhang, Juan Tao
J Am Acad Dermatol. 2025 Jul;93(1):e9-e10.
PMID: 39894363 DOI: 10.1016/j.jaad.2025.01.071
87.衰老与迟发性银屑病风险的关联：来自英国生物银行队列的证据
Association of aging and the risk of late-onset psoriasis: Evidence from the UK Biobank cohort
Ziye Yang, Fan Wang, Tongtong Zhang, Rui Mao, Ji Li
J Am Acad Dermatol. 2025 Jun;92(6):1375-1377.
PMID: 39952434 DOI: 10.1016/j.jaad.2025.01.070
88.利特昔单抗治疗儿童斑秃的有效性与耐受性：病例系列研究
Effectiveness and tolerability of ritlecitinib in children with alopecia areata: A case series
Jundong Huang, Jia Jian, Min Li, Ruxin Ji, Ji Li, Wei Shi
J Am Acad Dermatol. 2025 Jun;92(6):1395-1397.
PMID: 39909343 DOI: 10.1016/j.jaad.2025.01.090
89.1990年至2021年全球特应性皮炎患病率和负担的时间趋势
Temporal trends in the prevalence and burden of atopic dermatitis worldwide from 1990 to 2021
Zhichen Li, Yi Xiao, Xiang Chen, Xiaoyu Gu, Juan Su
J Am Acad Dermatol. 2025 Jun;92(6):1379-1381.
PMID: 39894365 DOI: 10.1016/j.jaad.2025.01.075
90.甲板剥脱是银屑病关节炎严重程度的最重要危险因素：一项中国单中心回顾性研究
Nail plate crumbling is the most significant risk factor for severe psoriatic arthritis: A Chinese single-center retrospective study
Yijie Liu, Minjia Tan, Kun Hu, Jiashuai Li, Lu Jian, Yizhang Liu, Yongfang Duan, Ruizhen Liu, Haoqun Zhang, Junchen Chen, Mi Zhang, Yehong Kuang
J Am Acad Dermatol. 2025 Jun;92(6):1429-1431.
PMID: 39956197 DOI: 10.1016/j.jaad.2025.02.026
91.将地区差异与人口统计学特征纳入黑色素瘤公共卫生策略
Incorporating regional variability and demographic insights into melanoma public health strategies
Jixin Chen, Qinxin Zhou
J Am Acad Dermatol. 2025 Jun;92(6):e205.
PMID: 39971249 DOI: 10.1016/j.jaad.2024.11.087
92.对“皮肤科手术中使用塑料一次性卷发梳进行头发牵拉”的评论
Comment on "The use of plastic, disposable combs for hair retraction in dermatologic surgery"
Chao Lian, Meng-Ting Wei, Xiao-Jun Liu, Xue-Lei Li, Xuan-Fen Zhang
J Am Acad Dermatol. 2025 Jun;92(6):e185-e186.
PMID: 39880173 DOI: 10.1016/j.jaad.2024.12.045
93.金属网辅助计算机断层扫描定位软组织异物用于微创皮肤外科手术
Metal mesh-assisted computed tomography localization of soft-tissue foreign bodies for minimally invasive dermatological surgery
Lin Zhong, Chao Lian, Xiao-Rong Lu, Yu-Bin Tian, Yong-Hong Qin, Xuan-Fen Zhang
J Am Acad Dermatol. 2025 Jun;92(6):e181-e182.
PMID: 39824357 DOI: 10.1016/j.jaad.2025.01.018
94.对Chen等人《将区域变异性与人口学见解纳入黑色素瘤公共卫生策略》的回应
Response to Chen et al's "Incorporating regional variability and demographic insights into melanoma public health strategies"
Hao Zhang, Yulin Sun
J Am Acad Dermatol. 2025 Jun;92(6):e207.
PMID: 39971247 DOI: 10.1016/j.jaad.2025.02.029
95.评论：对“接受生物制剂治疗的银屑病患者真菌感染风险：一项回顾性单中心队列研究”的回应
Commentary: Response to "Risk of fungal infection in patients with psoriasis receiving biologics: A retrospective single-center cohort study"
Meng Cao, Xia Zhang
J Am Acad Dermatol. 2025 Jun;92(6):e199-e200.
PMID: 39971246 DOI: 10.1016/j.jaad.2024.11.085
96.银屑病或银屑病关节炎患者在接受肿瘤坏死因子抑制剂、白细胞介素17抑制剂治疗期间发生主要不良心血管事件和静脉血栓栓塞事件的风险白细胞介素12/23抑制剂与白细胞介素23抑制剂：一项模拟靶点试验分析
Risk of major adverse cardiovascular events and venous thromboembolic events between patients with psoriasis or psoriatic arthritis on tumor necrosis factor inhibitors, interleukin 17 inhibitors, interleukin 12/23 inhibitors, and interleukin 23 inhibitors: An emulated target trial analysis
Tai-Li Chen, Jing-Yang Huang, Hui-Yun Lin, Yun-Ting Chang, Cheng-Yuan Li, James Cheng-Chung Wei
J Am Acad Dermatol. 2025 May;92(5):1015-1023.
PMID: 39736358 DOI: 10.1016/j.jaad.2024.12.025
97.银屑病患者对生物制剂早期反应不足预示6个月治疗失败：一项多中心前瞻性队列研究
Early inadequate response to biological agents portends treatment failure at 6 months in patients with psoriasis: A multicenter, prospective cohort study
Yuxiong Jiang, Lingling Yao, Xiaoyuan Zhong, Dawei Huang, Yu Wang, Yifan Hu, Shuang Xu, Qian Yu, Ying Li, Jiajing Lu, Yuling Shi
J Am Acad Dermatol. 2025 May;92(5):1153-1156.
PMID: 39864747 DOI: 10.1016/j.jaad.2025.01.055
98.阿布昔替尼干扰T-SPOT检测性能。潜伏性结核病再激活的结核病检测：一项体外研究
Abrocitinib interferes with the performance of T-SPOT.TB assay for latent tuberculosis reactivation: An in vitro study
Yiting Li, Xi Tan, Shu Nie, Bin Chen, Chaoshuai Zhao, Ran Liu, Zhouwei Wu
J Am Acad Dermatol. 2025 May;92(5):1124-1125.
PMID: 39848585 DOI: 10.1016/j.jaad.2025.01.026
99.人乳头状瘤病毒感染患者化脓性汗腺炎风险增加的探讨
Comments on the increased risk of hidradenitis suppurativa in patients with human papillomavirus infection
Tai-Li Chen, Tsung-Hsien Chang
J Am Acad Dermatol. 2025 May;92(5):e145-e146.
PMID: 39736359 DOI: 10.1016/j.jaad.2024.12.027
100.对Chen等人《关于人乳头瘤病毒感染患者化脓性汗腺炎风险增加的评论》的回应
Response to Chen et al, "Comments on the increased risk of hidradenitis suppurativa in patients with human papillomavirus infection"
Hui-Chin Chang, Shao-Wei Lo, Christine Hsu, Shiu-Jau Chen, Torsten Zuberbier, Shuo-Yan Gau
J Am Acad Dermatol. 2025 May;92(5):e147-e148.
PMID: 39736360 DOI: 10.1016/j.jaad.2024.12.028
101.对Vera等人“与生物制剂初治银屑病患者相比，白细胞介素-23抑制剂可降低心血管危险因素相关疾病发生率：一项回顾性队列研究”的回应
Response to Vera et al's "Interleukin-23 inhibition associates with lower incidence of cardiovascular risk factor type diseases compared to biologic naïve patients with psoriasis: A retrospective cohort study"
Wei-Wei Liu, James Cheng-Chung Wei
J Am Acad Dermatol. 2025 May;92(5):e157-e158.
PMID: 39884579 DOI: 10.1016/j.jaad.2024.12.044
102.对“坏疽性脓皮病诊断延迟对愈合结局及医疗资源利用的影响：一项前瞻性队列研究”的评论
Comments on "impact of delay of diagnosis of pyoderma gangrenosum on healing outcomes and health care utilization: A prospective cohort study"
Peng-Yu Chen, Sui-Qing Cai, Zhuang-Li Tang
J Am Acad Dermatol. 2025 May;92(5):e149-e150.
PMID: 39837415 DOI: 10.1016/j.jaad.2024.09.089
103.一项随机III期研究，旨在比较BAT2206（参照乌司奴单抗开发的生物类似药）与参比乌司奴单抗在中重度斑块型银屑病患者中的疗效与安全性
A randomized phase III study to compare efficacy and safety of BAT2206 (proposed ustekinumab biosimilar) with reference ustekinumab in patients with moderate to severe plaque psoriasis
Xiaoyong Man, Katya Zaharieva, Grażyna Pulka, Agnieszka Żebrowska, Yunhua Deng, Lally Mekokishvili, Xiaolei Yang, Yunpeng Qi, Cailing Gu, Qingfeng Dong, Min Zheng
J Am Acad Dermatol. 2025 Apr;92(4):724-731.
PMID: 39592058 DOI: 10.1016/j.jaad.2024.10.104
104.加巴喷丁是治疗面部潮红和红斑性毛细血管扩张性玫瑰痤疮的有效疗法：一项随机临床非劣效性试验
Gabapentin is an efficacy treatment for facial flushing and erythema of erythematotelangiectatic rosacea: A randomized clinical noninferiority trial
Jinyu Wei, Mei Wan, Qiquan Chen, Jian Fu, Ling Yang, Rongrong Ni, Lan Ge, Yanjun Dan, Xiao Chen, Minmin Kong, Ling Li, Shuguang Chen, Shichao Yang, Lian Zhang, Aiai Xia, Li Tang, Yanqi Zhang, Mingwang Zhang, Zhiqiang Song, Jian Li
J Am Acad Dermatol. 2025 Apr;92(4):927-930.
PMID: 39710117 DOI: 10.1016/j.jaad.2024.12.011
105.加巴喷丁可改善酒渣鼻的潮红症状，但对其他酒渣鼻症状或生活质量无改善作用：一项多中心、随机、双盲、安慰剂对照的先导研究结果
Gabapentin improves the flushing of rosacea, but not other rosacea symptoms or quality of life: Results from a multicenter, randomized, double-blind, placebo-controlled pilot study
Guangrong Ma, Yiya Zhang, Qiong Gao, Xin Yuan, Zhonglian Zhou, Dan Jian, Zhixiang Zhao, Ben Wang, Ji Li
J Am Acad Dermatol. 2025 Apr;92(4):920-922.
PMID: 39681269 DOI: 10.1016/j.jaad.2024.12.003
106.银屑病患者2型糖尿病的早期诊断：多因素诊断模型的构建
Early diagnosis of type 2 diabetes mellitus in patients with psoriasis: Construction of a multifactorial diagnostic model
Pengbo Gao, Chunxiao Wang, Sihan Wang, Xiaoce Cai, Jiao Wang, Xiaoying Sun, Fengming Hu, Xin Li
J Am Acad Dermatol. 2025 Apr;92(4):790-800.
PMID: 39709076 DOI: 10.1016/j.jaad.2024.11.066
107.表皮海绵状朗格汉斯细胞聚集（而非嗜酸性粒细胞）是过敏性接触性皮炎诊断的线索：170例经临床及斑贴试验确诊病例系列分析
Epidermal spongiotic Langerhans cell collections, but not eosinophils, are a clue to the diagnosis of allergic contact dermatitis: A series of 170 clinically- and patch test-confirmed cases
Peggy A Wu, Jiejun Wu, Regina Liu, Sydney Sullivan, Olivia Keller, Leah Caro-Chang, Yuden Pemba, Maxwell A Fung
J Am Acad Dermatol. 2025 Apr;92(4):853-860.
PMID: 39709083 DOI: 10.1016/j.jaad.2024.11.062
108.大范围上部螺旋缘缺损的简易局部复合皮瓣
Simple local composite flap for a large superior helical rim defect
Wenjia Yang, Yong Hu, Yu Mao, Jianzhong Peng, Xianyan Luo
J Am Acad Dermatol. 2025 Apr;92(4):e93-e94.
PMID: 39389426 DOI: 10.1016/j.jaad.2024.09.047
109.FRONTIER-2：口服JNJ-77242113治疗中重度斑块型银屑病的2b期长期扩展剂量探索研究
FRONTIER-2: A phase 2b, long-term extension, dose-ranging study of oral JNJ-77242113 for the treatment of moderate-to-severe plaque psoriasis
Laura K Ferris, Jerry Bagel, Yu-Huei Huang, Andrew E Pink, Stephen K Tyring, Georgios Kokolakis, Amy M DeLozier, Shu Li, Yaung-Kaung Shen, Charles Iaconangelo, Takayuki Ota, Robert Bissonnette
J Am Acad Dermatol. 2025 Mar;92(3):495-502.
PMID: 39549848 DOI: 10.1016/j.jaad.2024.10.076
110.关于通过FAERS评估抗癌治疗相关皮肤不良事件
Regarding assessment of anticancer therapy-related dermatologic AEs via FAERS
Liqi Li
J Am Acad Dermatol. 2025 Mar;92(3):e65.
PMID: 39522724 DOI: 10.1016/j.jaad.2024.09.076
111.使用A型肉毒素治疗后咬肌突出度的减轻：一项随机2期研究的初步结果
Reduction of masseter muscle prominence after treatment with onabotulinumtoxinA: Primary results from a randomized phase 2 study
Jean Carruthers, Steven Liew, Jason K Rivers, Shyi-Gen Chen, Shannon Humphrey, Grace Pan, Beta Bowen, Elisabeth Lee, Mitchell F Brin
J Am Acad Dermatol. 2025 Mar;92(3):464-472.
PMID: 39522729 DOI: 10.1016/j.jaad.2024.10.064
112.富血小板血浆联合微针及外用米诺地尔治疗难治性重度雄激素性脱发的疗效观察
Therapeutic efficacy of platelet-rich plasma combining with microneedling and topical minoxidil in refractory severe androgenic alopecia
Yanhua Li, Chenlei Dai, Yizhou Wang, Guangyu Lu, Jun Zhang, Yuqian Li, Guanghui Shao, Xiaoqin Jia, Xufeng Du
J Am Acad Dermatol. 2025 Mar;92(3):590-592.
PMID: 39515661 DOI: 10.1016/j.jaad.2024.10.046
113.人乳头瘤病毒感染与新发化脓性汗腺炎风险增加相关：一项基于人群的队列研究
Human papillomavirus infection is associated with increased risk of new-onset hidradenitis suppurativa: A population-based cohort study
Shuo-Yan Gau, Shao-Wei Lo, Christine Hsu, Shiu-Jau Chen, Torsten Zuberbier, Hui-Chin Chang
J Am Acad Dermatol. 2025 Mar;92(3):444-451.
PMID: 39510386 DOI: 10.1016/j.jaad.2024.10.055
114.与原发性肢端黑色素瘤相比，痣相关性肢端黑色素瘤的复发率和死亡率更低：一项针对482例患者的多中心回顾性分析
Nevus-associated acral melanoma has lower risk of recurrence and mortality than de novo acral melanoma: A multicenter, retrospective analysis of 482 patients
Yiqun Zhang, Jin Wu, Xin Cai, Kui Jiang, Weizhen Zhang, Hongfeng Zhou, Zhongwu Li, Shijie Lan, Jiwei Liu, Fang Liu, Yan Wang, Hongxue Meng, Zhen Guo, Liang Guo, Xiang Ji, Mei Xiang, Xinxin Yang, Yongqi Li, Lu Feng, Yuhuan Mao, Di Wu
J Am Acad Dermatol. 2025 Mar;92(3):538-545.
PMID: 39577696 DOI: 10.1016/j.jaad.2024.11.029
115.副肿瘤性天疱疮与副肿瘤性自身免疫性多器官综合征的系统综述：临床特征及预后因素
A systematic review of paraneoplastic pemphigus and paraneoplastic autoimmune multiorgan syndrome: Clinical features and prognostic factors
Min Zou, Kun Zhan, Yue Zhang, Luyuan Li, Jishu Li, Jingya Gao, Xuemei Liu, Wei Li
J Am Acad Dermatol. 2025 Feb;92(2):307-310.
PMID: 39426525 DOI: 10.1016/j.jaad.2024.10.013
116.复合倍他米松微针透皮给药治疗斑秃的随机对照试验
Microneedle transdermal delivery of compound betamethasone in alopecia areata-A randomized controlled trial
Rui Qiao, Jiaping Zhu, Jing Fang, Hualing Shi, Ziye Zhang, Jin Nie, Yiping Ge, Tong Lin, Yiqun Jiang
J Am Acad Dermatol. 2025 Feb;92(2):269-275.
PMID: 39393548 DOI: 10.1016/j.jaad.2024.09.059
117.探索自杀与自伤行为：生物制剂治疗银屑病或银屑病关节炎的信号强度——基于FDA不良事件的10年真实世界药物警戒分析报告系统数据库
Exploring suicidal and self-injurious behaviors signal strength of biologics in treating psoriasis or psoriatic arthritis: A 10-year real-world pharmacovigilance analysis using the FDA Adverse Event Reporting System database
Yu-Fan Cheng, Ming Chen, Xiong-Yu Li, Cai-Lan Hou, Zhu Shen
J Am Acad Dermatol. 2025 Feb;92(2):327-329.
PMID: 39401612 DOI: 10.1016/j.jaad.2024.09.058
118.治疗前中性粒细胞与淋巴细胞比值可预测原发性黏膜黑色素瘤患者的生存率
Pretreatment neutrophil-to-lymphocyte ratio predicts survival in primary mucosal melanoma
Chian-Tzu Huang, Yi-Hua Liao, Jau-Yu Liau, Chia-Yu Chu, Yi-Shuan Sheen
J Am Acad Dermatol. 2025 Feb;92(2):340-343.
PMID: 39447757 DOI: 10.1016/j.jaad.2024.10.019
119.应用磁盘联合薄硅胶片进行耳垂瘢痕疙瘩切除术后压力治疗
Utilizing magnetic discs combined with thin silicone gel sheets for pressure therapy in earlobe keloid postexcision
Le Zhuang, Jieyan Su, Jing Jiao, Hang Li
J Am Acad Dermatol. 2025 Feb;92(2):e35-e36.
PMID: 39307354 DOI: 10.1016/j.jaad.2024.06.111
120.黑色素瘤全球负担趋势：基于1990-2021年全球疾病负担研究的综合分析
Global trends in melanoma burden: A comprehensive analysis from the Global Burden of Disease Study, 1990-2021
Yulin Sun, Yiming Shen, Qian Liu, Hao Zhang, Lingling Jia, Yi Chai, Hua Jiang, Minjuan Wu, Yufei Li
J Am Acad Dermatol. 2025 Jan;92(1):100-107.
PMID: 39343306 DOI: 10.1016/j.jaad.2024.09.035
121.夫那奇珠单抗在中重度慢性斑块型银屑病中的疗效与安全性：一项随机、双盲、安慰剂对照的3期临床试验
Efficacy and safety of vunakizumab in moderate-to-severe chronic plaque psoriasis: A randomized, double-blind, placebo-controlled phase 3 trial
Kexiang Yan, Fuqiu Li, Xiaodong Bi, Ling Han, Zhenghua Zhang, Rixin Chen, Yuye Li, Litao Zhang, Xiaohua Wang, Linfeng Li, Jianyun Lu, Ai'e Xu, Sen Yang, Yan Lu, Jianfang Sun, Zhiming Li, Xiaohong Zhu, Meiying Jiang, Siping Zhang, Wenqing Wang, Yanling Li, Zudong Meng, Hongyi Li, Kuanhou Mou, Xiuping Han, Shanshan Li, Aijun Chen, Xin Li, Donghua Liu, Chunlei Zhang, Chao Ji, Yu Wang, Hao Cheng, Xiaojing Cui, Xiaoyan Yao, Xiaoyan Bai, Guangchao Dong, Jinhua Xu
J Am Acad Dermatol. 2025 Jan;92(1):92-99.
PMID: 39332633 DOI: 10.1016/j.jaad.2024.09.031
122.口服阿布昔替尼治疗难治性斑秃：一项回顾性研究
Oral abrocitinib for treatment of refractory alopecia areata: A retrospective study
Yujing Zhang, Fang Wang, Xiangqian Li, Yan Zhao, Jianzhong Zhang, Wei Zhao, Cheng Zhou
J Am Acad Dermatol. 2025 Jan;92(1):153-155.
PMID: 39436336 DOI: 10.1016/j.jaad.2024.09.025
123.生物节律紊乱与黄褐斑的相关性：一项横断面调查
Correlation of biorhythmic disorders with melasma: A cross-sectional survey
Xuanxuan He, Li Chen, Shanglin Jin, Yuecen Ding, Zhongyi Xu, Leihong Xiang, Chengfeng Zhang
J Am Acad Dermatol. 2025 Jan;92(1):185-187.
PMID: 39374809 DOI: 10.1016/j.jaad.2024.09.050
124.成人起病性隆突性皮肤纤维肉瘤幸存者后续原发性恶性肿瘤风险：一项基于人群的研究
Risk of subsequent primary malignancies among survivors of adult-onset dermatofibrosarcoma protuberans: A population-based study
Jingxuan Huang, Jun Liu, Chengjiang Wei, Qingfeng Li, Zhichao Wang
J Am Acad Dermatol. 2025 Jan;92(1):e17-e19.
PMID: 39278315 DOI: 10.1016/j.jaad.2024.08.059
125.受剪纸艺术启发的分层皮片移植术：一种缓解白癜风手术方向偏差的可行方法
Split thickness skin graft transplantation inspired by paper-cutting: A feasible approach to mitigating surgical misorientation in vitiligo
Zhanghui Yue, Maxwell A Kishengere, Xun Zhou, Junhao Li, Yan Wang, Hengguang Zhao, Jianyun Lu, Dan Wang
J Am Acad Dermatol. 2025 Jan;92(1):e1-e2.
PMID: 39222881 DOI: 10.1016/j.jaad.2024.07.1525
126.中国受试者中酒精摄入与男性雄激素性脱发严重程度的关联：一项单中心横断面研究
The association between alcohol consumption and the severity of male androgenic alopecia in Chinese participants: A single-center cross-sectional study
Jinyan Zhang, Yan Wu, Fei Wang
J Am Acad Dermatol. 2025 Jan;92(1):175-177.
PMID: 39341354 DOI: 10.1016/j.jaad.2024.08.079
127.对Hasan等人的回应：“度普利尤单抗治疗特应性皮炎与皮肤T细胞淋巴瘤风险增加相关：一项回顾性队列研究”
Response to Hasan et al., "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T-cell lymphoma: A retrospective cohort study"
Yung-Tsu Cho, Chia-Yu Chu
J Am Acad Dermatol. 2025 Jan;92(1):e9-e10.
PMID: 39187014 DOI: 10.1016/j.jaad.2024.06.105
说明：以上列表按论文出版时间由近及远排列（时间倒序）。凡有中国单位（含港澳台）作者参与的论文均计入。
完
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本文内容基于已公开的临床研究数据、学术文献及行业信息整理，仅用于医学与行业信息交流，不构成任何具体的诊疗建议或用药推荐。文中提及的药物或治疗手段，部分仍处于临床研究阶段或尚未获批，其安全性和有效性需以监管部门最终批准及正式说明书为准。患者如有相关疾病或症状，请在专业皮肤科医生指导下进行规范诊疗，切勿依据本文信息自行判断或用药。
版权声明
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临床研究临床结果
100 项与 乌司奴单抗生物类似药（百奥泰） 相关的药物交易
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| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 克罗恩病 | 欧盟 | 2025-08-14 | |
| 克罗恩病 | 冰岛 | 2025-08-14 | |
| 克罗恩病 | 列支敦士登 | 2025-08-14 | |
| 克罗恩病 | 挪威 | 2025-08-14 | |
| 银屑病关节炎 | 美国 | 2025-05-22 | |
| 活动性中度克罗恩病 | 美国 | 2025-05-22 | |
| 活动性重度克罗恩病 | 美国 | 2025-05-22 | |
| 斑块状银屑病 | 美国 | 2025-05-22 | |
| 活动性中度溃疡性结肠炎 | 美国 | 2025-05-22 | |
| 活动性重度溃疡性结肠炎 | 美国 | 2025-05-22 |
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 溃疡性结肠炎 | 临床3期 | 美国 | 2021-06-22 | |
| 溃疡性结肠炎 | 临床3期 | 保加利亚 | 2021-06-22 | |
| 溃疡性结肠炎 | 临床3期 | 波兰 | 2021-06-22 | |
| 溃疡性结肠炎 | 临床3期 | 俄罗斯 | 2021-06-22 | |
| 银屑病 | 临床1期 | 中国 | 2020-08-08 |
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| 研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
|---|
临床3期 | 528 | 願艱簾鹽襯網衊選壓網(簾襯衊鏇艱壓襯憲遞鏇) = The secondary efficacy endpoints showed no obvious differences across all 3 groups. 淵鏇窪選糧觸積艱醖膚 (壓繭築廠鹽廠顧製鹽選 ) 更多 | 积极 | 2025-12-01 | |||
BAT2206 (UST-BAT2206) | |||||||
临床3期 | 278 | 糧窪觸構淵衊鹹衊獵範(蓋鬱鏇遞願構鑰襯餘窪) = 衊廠簾齋網艱廠簾簾襯 膚鹽鬱鹽簾淵簾壓憲選 (顧壓製願選獵蓋製餘簾, 2.6847) 更多 | 积极 | 2025-02-20 | |||
糧窪觸構淵衊鹹衊獵範(蓋鬱鏇遞願構鑰襯餘窪) = 製糧壓艱積艱壓糧窪襯 膚鹽鬱鹽簾淵簾壓憲選 (顧壓製願選獵蓋製餘簾, 2.6526) 更多 | |||||||
临床3期 | 556 | 襯鹹願壓鏇願衊衊簾餘(築憲衊糧繭窪壓遞鹹簾) = 显示出BAT2206与原研药高度相似 網窪網積獵糧簾蓋夢繭 (積鬱夢網餘構衊淵築選 ) 更多 | 积极 | 2023-11-29 | |||
临床1期 | - | 270 | 網鬱築範範獵構夢鬱築(遞壓齋鬱鏇襯鏇簾選餘) = Furthermore, all the groups had similar incidences of treatment-emergent adverse events, in which the majority of cases belonged to Common Terminology Criteria for the Classification of Adverse Events Grade 1 or 2. 顧夢鏇鹽鏇簾構簾夢夢 (鏇積衊淵積範鏇艱淵憲 ) | 积极 | 2022-11-22 | ||
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