Pegylated recombinant human endostatin(Simcere Pharmaceutical Group Ltd.)

The primary purpose of this study is to examine the safety, tolerability and pharmacokinetics of PEG-ENDO in combination with docetaxel in subjects previously treated or untreated (standard therapy is not suitable or without standard therapy) for advanced or metatatic non-small cell lung cancer (NSCLC) or other solid tumors.

研究健康志愿者对注射用聚乙二醇化重组人血管内皮抑制素单次给药的安全性、耐受性以及药代动力学参数，为后续临床试验制定给药方案提供依据。