Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer
Article
作者: Shaoda Ren ; Zhaoxue Wang ; Xiaojing Li ; Na Li ; Shuo Wang ; Meijuan Liu
A synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.