预约演示
更新于：2025-05-15
Arnica Extract
山金车提取物
更新于：2025-05-15
概要
基本信息
关联
5
项与 山金车提取物 相关的临床试验IRCT20231210060320N1
A comparative study of the effect of sheep animal oil and arnica ointment on the intensity of pain, edema and ecchymosis around the eyes after rhinoplasty
NCT05283434
Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries
NCT04677712
MOBI: A Phase 4, Open-Label Study to Assess Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite in Adult Females
100 项与 山金车提取物 相关的临床结果
登录后查看更多信息
100 项与 山金车提取物 相关的转化医学
登录后查看更多信息
100 项与 山金车提取物 相关的专利（医药）
登录后查看更多信息
67
项与 山金车提取物 相关的文献（医药）2024-08-13Current Pediatric Reviews
Strategies for Pain Management after Extraction of Primary Teeth: A Systematic Review of Randomized Clinical Trials
Article
作者: Alves, Lívia Araújo ; França, Lucas Santiago ; Rodrigues, Janina ; da Silva, Gabriela Seabra ; Palma, Luiz Felipe ; Tedesco, Tamara Kerber ; Raggio, Daniela Prócida
Background::
In dental extractions, particularly when local anesthesia is used, it usually
offers analgesic relief for a few hours. However, pain can become a notable concern in the immediate
postoperative period due to the trauma experienced by both soft and hard oral tissues.
Objectives::
This systematic review aimed to evaluate the most effective strategies for managing
postoperative pain in primary tooth extractions.
Methods::
Two examiners conducted a search across five electronic databases: MEDLINE (via
PubMed), Embase, Scopus, Web of Science, CENTRAL, and OpenGray. Studies were included if
they met the following criteria after reviewing their titles and abstracts: they involved children and
evaluated pain management following primary tooth extraction. Subsequently, articles that described
extractions performed under any form of sedation, were not conducted under local anesthesia,
in an outpatient setting, and in children aged 0 to 12 years, or were not randomized controlled
trials, were excluded.
Results::
The search yielded 374 relevant articles, of which 9 were included. Among these, 5 utilized
preoperative medications as a pain management strategy, one evaluated low-level laser therapy
(LLLT) postoperatively, one assessed calendula drops postoperatively, and another explored
virtual reality during the procedure and arnica in solution both pre and postoperatively.
Conclusion::
Among all the strategies evaluated, the strategy involving analgesics administered 30
minutes before tooth extractions was supported by better-designed studies. However, there is a
high risk of bias.
2024-05-01Journal of biomaterials applications
New approaches to second-degree burn healing: Polyvinyl alcohol membrane loaded to arnica combined to laser therapy
Article
作者: Gomes, Rodrigo César ; Fanelli, Camilla ; Gianini, Reinaldo José ; Komatsu, Daniel ; Noronha, Irene de Lourdes ; Cardoso, Carolina Silva ; Randazzo-Moura, Priscila ; dos Santos, Nelson Brancaccio ; de Carvalho, Filipe Feitosa
Second-degree burns require greater care, as the damage is more extensive and worrisome and the use of a biomaterial can help in the cell repair process, with better planning, low cost, and better accessibility. Arnica has anti-inflammatory and analgesic properties in skin lesions treatments and laser therapy is another therapeutic alternative for burns. Evaluate the effects of arnica incorporated into PVA associated or not with low intensity laser on burns in rats. PVA and PVA with arnica (PVA+A) were obtained and characterized physicochemically. Through in vivo studies, the effects of PVA and PVA+A with or without the application of laser on the lesions allowed histological and immunohistochemical analyzes. PVA+A was biocompatible and with sustained release of the active, being a promising pharmacological tool and confirmed that laser therapy was effective in accelerating the healing process, due to its potential biomodulator, improving inflammatory aspects, promoting rapid healing in skin lesions.
2024-01-01Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Can Topical Agents (Arnica and Mucopolysaccharide Polysulfate) Reduce Postoperative Pain, Edema and Trismus Following Mandibular Third Molar Surgery?
Article
作者: Akay, Neşet ; Şanal, Koray Onur
BACKGROUND:
Postoperative supplemental maintenance following mandibular third molar surgery remains an area of interest.
PURPOSE:
Topical agents can modulate inflammatory processes. The aim of the present study was to determine if topical application of arnica or mucopolysaccharide polysulfate (MPSP) reduces pain, trismus, and edema following the removal of impacted mandibular third molars.
MATERIALS AND METHODS:
A single center randomized controlled clinical trial was conducted. The patients were randomized into three groups: the control group (standard therapy [ST]: antibiotic + nonsteroidal anti-inflammatory drugs twice a day), the arnica group (arnica + ST), and the MPSP group (MPSP + ST). The patients' pain, trismus, and edema values were measured preoperatively and on postoperative days 1, 3, 5, and 10. Sex, age, and operation time were also included. Analyses included descriptive statistics, analysis of variance, post hoc tests, and determinations of intraclass correlation coefficients. Statistical significance was set at P < .05.
RESULTS:
Sixty patients with a mean age of 26.98 ± 10.88 years were included in the study; 55% were females and 45% were males. The mean operation time was 23.8 ± 3.27 minutes. According to the visual analogue scale scores (in centimeter units), the arnica and MPSP groups felt less pain than the control group until day 5 (0.6 ± 0.88, 3.75 ± 1.16, 4.75 ± 1.29, and 1.05 ± 1.10, respectively, for the arnica group; 0.35 ± 0.59, 3.25 ± 1.62, 5.0 ± 1.65, and 1.50 ± 1.32 for the MPSP group; and 1.30 ± 1.17, 5.75 ± 1.37, 7.05 ± 1.10, and 3.15 ± 1.53 for the control group; P < .05). The trismus was lower on days 1, 3, and 5 in the arnica group (-8.05 ± 2.82, -12.15 ± 3.1, and -2.15 ± 1.81, respectively) than in the control group (-12 ± 3.82, -15.65 ± 4.81, and -4±2.81, respectively) (P < .05). The edema was lower on days 1 and 3 in the MPSP group (0.95 ± 2.2 and 1.75 ± 3.7, respectively) than in the control group (2.45 ± 0.9 and 3.6 ± 0.8, respectively) (P < .05). Arnica and MPSP had similar pain-relieving action, but arnica was more effective at reducing trismus, while MPSP was more effective at reducing edema.
CONCLUSIONS:
Topical application of arnica or MPSP may have a beneficial effect on relieving pain 5 days after surgery, but arnica was also effective at reducing trismus, while MPSP was also effective at reducing edema. Both arnica and MPSP reduced postoperative sequelae.
1
项与 山金车提取物 相关的新闻（医药）
100 项与 山金车提取物 相关的药物交易
登录后查看更多信息
研发状态
10 条进展最快的记录, 后查看更多信息
登录
| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 急性疼痛 | 临床3期 | 美国 | - | 2021-07-15 |
| 肌肉骨骼损伤 | 临床3期 | 美国 | - | 2021-07-15 |
| 肌痛 | 临床3期 | 美国 | - | 2021-07-15 |
登录后查看更多信息
临床结果
临床结果
适应症
分期
评价
查看全部结果
N/A | - | Local cold with ice and oral analgesics and anti-inflammatories | 艱鑰繭築襯憲鬱鹽繭齋(襯餘糧蓋壓壓築淵繭簾) = Rapid pain relief and hematoma resorption were observed between the third and seventh day in all patients 獵構選範遞遞獵獵廠獵 (糧鏇憲艱糧願鹹築積衊 ) | - | 2024-04-01 | ||
临床4期 | 48 | (Cohort 1: CCH-aaes) | 膚獵齋獵遞選獵衊鹽鬱 = 壓選夢衊廠鹹廠糧觸顧 醖淵糧襯遞積觸衊構憲 (積築製積繭蓋願鹹艱壓, 蓋願築膚齋艱憲衊艱醖 ~ 築齋願糧積夢鏇夢觸夢) 更多 | - | 2023-08-21 | ||
Compression (Cohort 2: CCH-aaes + Compression Garment) | 膚獵齋獵遞選獵衊鹽鬱 = 淵獵願鑰選積膚範衊構 醖淵糧襯遞積觸衊構憲 (積築製積繭蓋願鹹艱壓, 艱醖積鹹襯積窪蓋構範 ~ 餘醖繭範鑰鹹積艱蓋鏇) 更多 | ||||||
N/A | 16 | 壓膚顧蓋膚鏇遞製遞遞(艱糧鹽齋獵淵鬱顧積壓) = 繭獵窪範壓願遞選繭蓋 獵憲繭壓襯願壓築艱範 (鏇衊網壓窪窪鹽鹹觸鏇, 0.68) 更多 | - | 2012-12-04 |
登录后查看更多信息
转化医学
使用我们的转化医学数据加速您的研究。
登录
或
药物交易
使用我们的药物交易数据加速您的研究。
登录
或
核心专利
使用我们的核心专利数据促进您的研究。
登录
或
临床分析
紧跟全球注册中心的最新临床试验。
登录
或
批准
利用最新的监管批准信息加速您的研究。
登录
或
特殊审评
只需点击几下即可了解关键药物信息。
登录
或
Eureka LS:
全新生物医药AI Agent 覆盖科研全链路，让突破性发现快人一步
立即开始免费试用!
智慧芽新药情报库是智慧芽专为生命科学人士构建的基于AI的创新药情报平台，助您全方位提升您的研发与决策效率。
立即开始数据试用!
智慧芽新药库数据也通过智慧芽数据服务平台，以API或者数据包形式对外开放，助您更加充分利用智慧芽新药情报信息。
生物序列数据库
生物药研发创新
免费使用
化学结构数据库
小分子化药研发创新
免费使用