The investigators hypothesize that single oral high dose supplementation with vitamin A will reduce the incidence of moderate-severe chronic graft-versus-host disease (GVHD) compared with placebo.

开始日期2025-03-01

申办/合作机构

Children's Hospital & Medical Center

IRCT20090901002394N51

/ Suspended临床3期

The effect of vitamin A supplementation on severity of disease symptoms and anthropometric indices in children with attention deficit hyperactivity disorder (ADHD)

开始日期2025-02-19

申办/合作机构

Iran University of Medical Sciences & Health Services

ChiCTR2500096475

/ Suspended早期临床1期IIT

The Effects of Vitamin A and Heat Exposure on Metabolic Health: A Single-Center, Randomized Controlled Trial

开始日期2025-01-26

申办/合作机构-

100 项与维生素A 相关的临床结果

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100 项与维生素A 相关的转化医学

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100 项与维生素A 相关的专利（医药）

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41,808

项与维生素A 相关的文献（医药）

2025-12-31·ANNALS OF HUMAN BIOLOGY

Lactose in human milk is associated with lower rates of infection during a drought

Article

作者: Fujita, Masako ; Wander, Katherine

BACKGROUND:

Infants given mothers' milk have higher resistance against infections than formula-fed counterparts. This protection is likely multifactorial, with roles for both milk immune factors and nutrients, particularly under elevated nutritional and disease stress.

AIM:

This study evaluated several milk nutrients/immune factors to assess associations with infant infectious disease during a severe drought.

SUBJECTS AND METHODS:

The study analysed morbidity recall data from Kenyan mother-infant dyads surveyed during a historic drought (n 84). Predictors of interest in logistic regression models of infant infections included milk sIgA, lactoferrin, retinol, folate receptor-α, fat, protein, and lactose. Adjustment variables included dyadic demographic characteristics and maternal infection. Akaike Information Criterion guided model fit assessment. Interactions between variables were allowed in the best-fit model.

RESULTS:

In the best-fit model, lactose was inversely (OR 0.93; 90% CI 0.89, 0.97), and maternal infection was positively (OR 2.80; 90% CI 1.04, 7.52) associated with infant infection. Milk immune factors (sIgA, lactoferrin) were not included in the final models.

CONCLUSION:

Mothers' milk may protect infants against infection through a broad range of immune and nutrient components. In the context of severe drought with heightened nutritional and disease stress, lactose may protect against infection or decrease in the presence of an infection.

2025-12-31·Journal of the International Society of Sports Nutrition

Survey of nutritional intake status in college baseball players

Article

作者: Aoyama, Yuka ; Tanaka, Mamoru ; Seguchi, Manato ; Iio, Yoko ; Kozai, Hana ; Mori, Yukihiro ; Ito, Morihiro

BACKGROUND:

Diet is closely related to exercise performance. To improve athletes' performance and manage their condition, it is important to get sufficient energy and various nutrients. Thus, it is necessary that athletes understand their nutritional intake status to improve performance and maintain health. This study aimed to explore the nutritional intake status of college baseball players using the Food Frequency Questionnaire (FFQ). Furthermore, the characteristics of their nutritional intake status with respect to athletic performance were evaluated. The result of this studyprovide an opportunity for many under-developed college athletes with irregular lifestyles to recognize and improve their nutritional problems.

METHODS:

In October 2022, a questionnaire survey of 116 male members of a college baseball club was conducted. Of whom, 100 (94.3%) members responded to the survey and 92 (92.0%) provided valid responses. The survey items included basic characteristics such as college grade and type of living arrangement, and information on living conditions, e.g. whether the participant ate breakfast. Nutritional intake was evaluated using the FFQ. Players were divided into the first (regular players in official games), second (bench players in official games), third (players who may join the second or higher team in the future), and fourth teams (players who do not belong to the first to third teams); these categories were used as a marker of performance level. The Kruskal-Wallis test was used to analyze the association between the performance levels of baseball players and the intake of each nutrient and food group obtained by the FFQ. For items that showed a significant association, inter-group comparison was performed using the Dunn-Bonferroni method.

RESULTS:

Carbohydrate intake was greater in the second team compared with the third and fourth teams; saturated and monounsaturated fatty acid intake was higher in the third team compared with the fourth team. Calcium, zinc, copper, manganese, insoluble dietary fiber, iodine, and molybdenum intake was higher in the second team compared with the fourth team. Intake of grains, sugar, dairy, and total energy was significantly higher in the second team compared with the fourth team. However, the protein intake ratio was significantly lower in the second team compared with the fourth team. Overall, energy deficiency and associated deficiencies in protein, fat, and carbohydrate were observed, in addition to dietary fiber and calcium deficiencies. The intake of several food groups appeared inadequate, such as potatoes, beans, vegetables, fruits, eggs, milk, and fats.

CONCLUSIONS:

The study showed deficiencies in the amount of energy and nutrients such as protein, fat, and carbohydrate in college baseball players. Differences in the intake of carbohydrate, calcium, and insoluble dietary fiber among different performance levels were observed, with significantly higher intake of carbohydrate, calcium, and insoluble dietary fiber in the second team. Implementing organized and strategic remedial measures and athletes' identification of nutritional problems are vital to overcome nutritional and energy deficiencies. This study provides useful information for the development of strategies to support nutritional intake in college baseball players.

2025-12-31·ANNALS OF MEDICINE

The role of fat-soluble vitamins on bone metabolism and osteoporosis: a literature review

Review

作者: Cao, Wenhai ; Zhu, Yue ; Li, Hongyang ; Tao, Lin

PURPOSE:

The purpose of this review is to discuss the role of fat-soluble vitamins in bone metabolism and explore whether there is a relationship between each fat-soluble vitamins in the occurrence and development of osteoporosis.

METHODS:

We selected several databases, including PubMed, PubMed Central (PMC), Embase, and Web of Science, as the primary sources for the search. Keywords closely related to the subject of this study, such as 'osteoporosis', 'vitamin A', 'vitamin D', 'vitamin E', 'Vitamin K', 'ferroptosis', 'osteoblast' and 'osteoclast', were used in the search. The search deadline is April 20, 2025. All included clinical studies were graded for critical analysis GRADE.

RESULTS:

Among 573 reviewed articles, 182 were included (52 met GRADE criteria: A=10, B=26, C=11, D=5; 130 N/A). Vitamins D and K enhance osteoblast differentiation via RUNX2/ALP upregulation. Vitamin A's bone effects remain debated, potentially interacting with vitamin D. Vitamins E and K may jointly regulate bone metabolism as ferroptosis inhibitors.

CONCLUSION:

i Fat-soluble vitamins (D, K, E) may positively impact bone mineral density (BMD), while vitamin A's effects remain controversial, potentially harming BMD at high doses. Current single-vitamin studies have limitations; future research should explore combined vitamin interactions to advance osteoporosis diagnosis and treatment.

252

项与维生素A 相关的新闻（医药）

2025-07-29

·梅斯医学

缓解8大症状！复合维生素矿物质立“大“功！《亚太临床营养学杂志(APJCN)》2025发表真实世界研究，感冒流感减少42.8%！

自古以来，抵御疾病、强健体魄就是人类不懈的追求，为此，我们塑造了“正气”、“元气”等概念，也尝试了各种方法，试图为我们的身体筑起防御高墙。神医华佗创编“五禽戏”，模仿动物动作以疏通经络、强身健体，本质上是一场古老的“免疫力提升”的实践。古人寻访仙草灵药，熬制滋补汤剂，也多是期盼能扶正祛邪，百病不侵。时光流转至今日，现代流行病学研究表明，30-50岁成年人每年都会经历2-3次感冒。仅在中国，每年报告的流感样疾病就约340万例，导致每年估计流感相关死亡人数高达88,100例。1应对日常中常见的感冒和流感，“免疫力”这面盾牌是否足够坚固？我们投入的种种努力，效果究竟如何？现代人提升免疫力的武器库已空前丰富，但“经典”选手——我们日常服用的复合维生素矿物质制剂(MVM)——正又进入科研界的视野，并带来令人瞩目的新研究发现。2025年7月19日，中国医学科学院北京协和医院临床营养科的科研人员在亚太临床营养学会 (Asia Pacific Clinical Nutrition Society, APCNS) 官方期刊《亚太临床营养学杂志(英文版)》(Asia Pacific Journal of Clinical Nutrition, APJCN)中发表了一项基于中国人群大规模真实世界研究，发现了复合维生素矿物质制剂(MVM)全新健康作用。1这项研究在2024年4月-7月期间，纳入了全国18省份3415名社区居民（MVM组1,549名，对照组1,866名），经倾向性评分匹配（PSM）后，两组各保留1,130人，人口学特征均衡。评估了常规使用复合维生素矿物质补充剂（MVM）对中国人群中急性上呼吸道感染（AURIs）包括感冒和流感的流行率和症状严重性的影响。其研究结果令人振奋：MVM组的AURIs期间发生率显著低于对照组，（31.7%比44.8%，P<0.001）。对于年龄≥45岁的参与者保护效应最强（OR=0.407，P <0.001）。即：规律服用至少三个月复合维生素矿物质补充剂，可显著降低中国人群感冒和流感的发生达42.8%，对年龄≥45岁人群的保护作用更为突出。在感冒和流感的症状方面，复合维生素矿物质显著减少感冒和流感的鼻塞、喉咙痛、头痛、腹泻、打喷嚏、疲乏症状。研究同时还发现规律服用复合维生素和矿物质的人群，ISQ免疫评分普遍高于未服用人群。既往研究的MVM配方异质性导致结果可行性差。1本研究采用标准化MVM制剂: 多维元素片29/29-Ⅱ（OTC，商品名“善存/银善存”），由赫力昂生产制造。这项2025年新研究首次基于中国社区大样本证实MVM对AURIs的预防作用，为我们理解营养补充与免疫力、上呼吸道感染的关系，打开了新视角，也为大众日常抵抗并管理感冒和流感症状，为公共卫生干预提供了循证依据。 “日常营养”进阶“防感先锋” 近年来，复合维生素补充剂在免疫领域的价值日益凸显。本研究更进一步，将复合维生素矿物质日常补充与显著降低普通感冒/流感症状的患病率和症状严重性建立起明确关联，这项回顾性的真实世界研究是在中国的社区人群中进行的。并且采用倾向评分匹配（PSM）方法以1:1比例匹配样本，增加了MVM组和对照组的可比性；分析包括未匹配和匹配数据集，使用广义线性模型（GLMs）评估组间差异。防的更好，缓解8大症状这项研究显示，在相似生活环境下，规律补充复合维生素和矿物质（MVM）的中国人群，其抵御普通感冒和流感的能力显著提升，感染风险降低了42.8%(OR=0.572, p<0.001)。1这意味着，MVM可能有效增强了中国人群的“免疫韧性”，为健康防线提供了循证医学证据。即使不小心“中招”，补充MVM还能缓解8大流感感冒症状。研究发现，对照组报告的重度症状的期间发生率比例更高，而MVM组报告的轻微症状的期间发生率高于对照组，在轻微发热（81.6% vs. 74.7%，P =0.037）、轻微流鼻涕（74.4% vs. 68.0%，P =0.031）、轻微鼻塞（71.8% vs. 63.6%，P =0.011）、轻微喉咙痛（72.7% vs. 64.2%，P =0.005）、轻微咳嗽（73.0% vs. 65.8%，P =0.009）、轻微打喷嚏（82.2% vs. 74.0%，P =0.009）、轻微肌肉疼痛（82.0% vs. 72.9%，P =0.014）和轻微疲劳（74.7% vs. 68.6%，P =0.045）等症状上均存在统计学显著差异。1这也就意味着，在缓解以上8种症状上，复合维生素矿物质又立下了“大”功！同样重要的是，研究使用专门的免疫评分（ISQ）发现，MVM组免疫状态问卷（ISQ）评分≥6的参与者比例较高（95.9%比90.7%，OR=1.79，P<0.001）。1这提示我们，MVM的摄入可能有助于优化身体的整体免疫功能状态，让免疫系统处于更佳的“备战”水平。研究同时收集了受试者的饮食和运动数据，包括每日蔬菜、肉类、水产品、水果、牛奶或豆浆的摄入量、饮酒频率和身体锻炼的情况。在MVM组和对照组之间存在基线差异的情况下，通过采用倾向评分匹配（PSM）方法，使得这些差异得以最小化，这种方法有效减少了与生活方式因素相关的潜在偏移，从而增强了该研究结果的科学可信性。人体免疫系统的三道防线微量营养素，包括维生素和矿物质，在免疫反应的每个阶段都起着关键作用。当病原体入侵时，首先启动的是第一道防线，即物理化学屏障，包括皮肤、粘膜和体液等，它们能阻挡病原体进入体内。维生素A、D、C、B6、B9（叶酸）、B12以及矿物质锌和铁等，是构建和修复这道物理屏障、保持其健康功能的核心营养素。2若病原体突破这道屏障，第二道防线（非特异性免疫）便会启动，在病原体入侵的0-4h，会触发先天固有免疫应答，维生素A、D、C、E、B6、B9、B12、铁、锌、铜、硒、镁等维生素矿物质促进了固有免疫细胞的增殖、分化、效应功能及迁移，固有的免疫应答分为固有免疫细胞反应，包括巨噬细胞、NK细胞和中性粒细胞；以及固有免疫生化物质，包括抗菌肽和抗菌蛋白、补体、血清游离模式识别受体。在免疫应答的过程中会产生有害的“活性氧”。维生素C、E以及铁、锌、铜、硒、镁等矿物质会作为抗氧化剂和抗炎因子，帮助清除这些有害物质，防止过度的组织损伤；维生素A、D、C、铁、铜、硒则直接参与杀伤病原体（“抗菌效应”）。在病原体入侵后的4-96h，会产生炎症反应，导致血管舒张，血管通透性增加，炎性调节主要由维生素A、D、C、E、B6、B9、B12、锌、铜、硒、镁控制，炎症介质释放等有助于启动适应性免疫。2在病原体入侵超过96h后，第三道防线：适应性免疫应答（特异性）也会参与其中。树突状细胞（DC）会捕获病原体抗原，将其“呈递”给T淋巴细胞，促使T淋巴细胞活化并分化为不同类型的辅助性T细胞（主要是TH1和TH2）。维生素A、D、C、E、B6、B12、铁、锌、铜、硒在其中发挥了重要的作用。细胞免疫由TH1主导， TH1细胞分泌特定的细胞因子，激活巨噬细胞等抗原呈递细胞（APC），直接杀伤被感染的细胞。维生素A、D、C、E、B6、B9、B12、铁、锌、铜、硒促进了以细胞为介导的免疫反应；体液免疫由TH2主导，TH2细胞辅助B细胞增殖并分化成浆细胞，后者产生针对特定病原体的“抗体”（免疫球蛋白）。在这个过程中，维生素A、D、C、E、B6、B9、B12、锌、铜、硒、镁等维生素矿物质促进了抗体的产生与效应功能。3复合维生素矿物质：你的免疫力小帮手，全球多项研究来撑腰！不仅是中国，世界范围内对于复合维生素矿物质也展开了研究，在面对传染性更强的COVID-19新冠病毒时，MVM也是一面可靠的“屏障”。在2021年发表的一项涉及超过44.5万名来自英国、美国和瑞典的COVID-19症状研究应用用户的观察性研究中，研究发现服用复合维生素矿物质与降低新冠病毒（SARS-CoV-2）感染风险之间存在显著关联。在这项研究里，服用复合维生素补充剂的人群具有适度的保护效应，在整个英国人群中，检测阳性SARS-CoV-2的风险降低了13%，在美国人群中降低了12%，在瑞典人群中降低了22%。3针对不同人群，复合维生素矿物质制剂在提升免疫指标方面已有多项研究支持。河南省疾控中心发表于《营养学报》(2006)的一项研究关注中老年人补充多种营养素后的营养与免疫状态变化，结果发现，实验组的体液免疫指标（血清IgA、IgG、IgM 水平）均高于对照组，提示这类营养补充有助于增强体液免疫功能。4而在另一项聚焦2型糖尿病患者的研究中，来自解放军总医院营养科发表于《营养学报》(2010)的研究发现，补充微量营养素后，这类患者外周血中的淋巴细胞、CD4+细胞数量明显上升，CD8+细胞的升高受到抑制，CD4+/CD8+比例提升，意味着整体免疫系统更具抗感染能力。5此外，由复旦大学公共卫生学院发表于《环境与职业医学》(2004)的一项研究针对40~65岁人群的研究也显示，适量补充微量营养素可能有助于维持和改善自然杀伤（NK）细胞的活性，从而在一定程度上减缓免疫系统的衰老过程。6总而言之，随着国内外复合维生素矿物质的研究不断开展和发表，研究者们逐渐揭示出它们的潜在的提示免疫力并抵御感冒流感等的益处，这些不起眼的“基础微量营养素”，没有昂贵的价格标签，但在每天日常生活中用温和的方式，帮我们守护免疫健康，抵御常见上呼吸道感染疾病(感冒、流感)侵袭。参考文献：1. F Wang, et al. Multivitamin-mineral supplementation prevents acute upper respiratory tract infections[J]. Asia Pac J Clin Nutr 2025;34(4):596-609. https://apjcn.qdu.edu.cn/34_4_596.pdf 2. Gombart AF, et al. Nutrients. 2020 Jan 16;12(1):236. 3. Louca P, et al. BMJ Nutr Prev Health. 2021 Apr 19;4(1):149-157.4. 张丁,等. 营养学报 . 2006;28(4) :329-331.5. 景洪江,等. 营养学报 . 2010;32(1) :11-16.6. 郭红卫,等. 环境与职业医学 . 2004;21 (05) :374-376.免责声明：本文仅作最新前沿信息交流之目的，仅供医疗卫生行业专业人士阅读参考，文中所有观点不代表梅斯医学立场，亦不代表梅斯医学支持或反对文中观点。如需获得治疗方案指导，请前往正规医院就诊！

临床研究

2025-07-22

·PRNewswire

Particles for Humanity Completes Process Validation for Manufacturing PFH-VAP

CAMBRIDGE, Mass., July 22, 2025 /PRNewswire/ -- Particles for Humanity has successfully completed process validation for the commercial-scale manufacturing of PFH-VAP, the company's lead product. This novel, dry powder, vitamin A formulation is developed for use in large scale food fortification and manufactured at LIS by Lesaffre in Cérences, France. This critical milestone confirms that PFH-VAP can be produced consistently, at high quality, and is ready for commercial use, advancing the company's mission to address vitamin A deficiency in Africa. The validation confirmed that every step of the production process performs reliably, from mixing ingredients to drying and packaging the final product. This work utilized LIS by Lesaffre proven expertise in food ingredient manufacturing, established food-grade validation framework, and their GMP (good manufacturing practices)-compliant systems. "Completing process validation at LIS is a significant step toward bringing PFH-VAP to market at scale," said Sherri Oberg, CEO of Particles for Humanity. "This achievement strengthens our capacity to meet commercial demand and deliver on our mission to get stable vitamin A to people in Africa who need it." PFH-VAP was developed for use in large scale food fortification to withstand the hot and humid conditions commonly found in West Africa that often cause vitamin A to degrade. This degradation limits the impacts of vitamin A fortification programs. The first application of PFH-VAP is being developed to fortify bouillon, which is consumed by 80% to 99% of households in West Africa, including in low-income communities where vitamin A deficiency (VAD) is most common. In March 2025, Particles for Humanity announced a license agreement with Hexagon Nutrition Limited for rights to manufacture and distribute PFH-VAP for fortifying bouillon cubes in Africa. Through its partnerships with LIS by Lesaffre in France, and Hexagon Nutrition in India, Particles for Humanity is thrilled to be one step closer to bringing stable vitamin A to people who need it most. Particles for Humanity transforms early-stage medical technology into products for people living in low and lower-middle income countries, with 100% of funding from philanthropy. Its rigorous product development process is based on local stakeholder input and is focused on financially sustainable product opportunities. Visit or contact [email protected] With 2 production sites (France and Poland) and 50 years of experience in spray drying of several hundred different products, LIS by Lesaffre is the ultimate drying partner in Europe for food, feed, nutraceuticals, cosmetics and pharmaceuticals markets. Visit lesaffre-ingredients-services.com. SOURCE Particles for Humanity WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED

引进/卖出

2025-07-03

·echemi

NHU Projects Profit Surge of Up to 70 Percent in H1 2025 Reaching 37.5 Billion Yuan

On July 1, 2025, NHU (Zhejiang NHU Co., Ltd.) released its 2025 interim earnings forecast, expecting net profit attributable to shareholders to hit 33 billion to 37.5 billion yuan, marking a 50%-70% year-on-year growth. For Q2 alone, NHU anticipates net profit of 14.2 billion to 18.7 billion yuan. This profit surge is largely driven by the nutrition products segment, where increased sales volumes and higher prices for key products boosted performance. NHU has maintained strong profit momentum from 2024, when its annual revenue reached 216.1 billion yuan, up 42.95%, and net profit grew 117.01% to 58.69 billion yuan. NHU operates across four core business areas: Nutrition Products: The company produces a wide range of vitamins (E, A, D3, B12, etc.), amino acids (methionine, serine, cystine), and coenzymes like Q10. These are used in feed additives, food supplements, and health products. Significant advancements include achieving 30 million tons/year capacity, nearing completion of a 180,000 tons/year methionine project, and stable operation of the cystine production line. Fragrances and Flavors: NHU specializes in producing ingredients such as citral, linalool, and menthol, widely used in personal care and food industries. Ongoing projects include the fragrance industrial park Phase I and the SA aldehyde series project. High-Performance Polymers: NHU focuses on PPS, PPA, HDI, and other materials for automotive, electronics, and environmental applications. Key achievements include the start of a nylon materials project in Tianjin and the first phase of the IPDI project reaching production. Pharmaceutical APIs: NHU produces vitamins, antibiotics, and intermediates for active pharmaceutical ingredients (APIs), including moxifloxacin HCl and vitamin A. NHU’s strategic investments in R&D and capacity expansion have positioned it for sustained growth across multiple industries, from nutrition and healthcare to new energy vehicles and industrial applications.

临床1期财报

100 项与维生素A 相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
D06543	维生素A	A11CA01	DB00162

研发状态

批准上市

10 条最早获批的记录,

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适应症	国家/地区	公司	日期
寻常鳞癣	日本	Sannova KK	1979-09-08
糠疹	日本	Sannova KK	1979-09-08
角软化症	日本	Alfresa Pharma Corp.	1976-08-10
角化病	日本	Alfresa Pharma Corp.	1976-08-10
夜盲症	日本	Alfresa Pharma Corp.	1976-08-10
维生素a缺乏症	日本	Alfresa Pharma Corp.	1976-08-10
干眼症	-	-	-

未上市

10 条进展最快的记录,

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适应症	最高研发状态	国家/地区	公司	日期
支气管肺发育不良	临床前	澳大利亚	Orphanix	2025-07-01
早产儿视网膜病变	临床前	澳大利亚	Orphanix	2025-07-01

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


NCT01203488 (Pubmed)	临床3期	支气管肺发育不良	807	Vitamin A therapy	範簾憲構簾獵鏇壓範願(齋鬱範範齋鏇簾壓糧繭): RR = 0.89 (95% CI, 0.8 ~ 0.99)	积极	2021-05-15
				Vitamin A (Control group)
ACTRN12616000408482 (Pubmed \| Pediatrics)	N/A	支气管肺发育不良	188	Enteral water-soluble vitamin A	選艱積壓襯選壓鬱衊獵(繭廠夢蓋鑰餘範願網遞) = 膚齋膚遞衊選鹹鏇膚網網衊鏇製壓壓願鹹網齋 (範遞艱鬱糧簾蓋構觸襯 ) 更多	-	2021-01-01
				Placebo	選艱積壓襯選壓鬱衊獵(繭廠夢蓋鑰餘範願網遞) = 範簾範夢獵蓋簾窪鑰築網衊鏇製壓壓願鹹網齋 (範遞艱鬱糧簾蓋構觸襯 ) 更多
NCT00817661 (Pubmed \| J Nutr)	N/A	怀孕	112	Vitamin A supplementation	膚鏇獵壓齋襯網鹹憲壓(膚淵鏇憲鏇築糧簾網遞) = 觸構糧壓顧艱餘壓餘憲繭顧網築鹽憲範餘獵餘 (鑰積淵壓餘艱蓋築衊襯 )	-	2018-12-01
				Vitamin A (Placebo)	膚鏇獵壓齋襯網鹹憲壓(膚淵鏇憲鏇築糧簾網遞) = 選鹽艱衊構範鏇顧繭廠繭顧網築鹽憲範餘獵餘 (鑰積淵壓餘艱蓋築衊襯 )
NCT00514891 (Pubmed \| Pediatrics)	临床4期	-	7,587	Vitamin A supplementation	蓋鹽網簾膚簾襯鑰艱齋(餘餘糧願選簾構窪鏇窪): MRR = 0.91 (95% CI, 0.59 ~ 1.41)	-	2014-09-01
				vitamin A (Placebo)
NCT01225289 (CTgov)	临床4期	复发-缓解型多发性硬化	36	Vitamin A (With Multiple Sclerosis/ Vitamin A)	醖簾願鹽襯壓獵選選襯(遞廠糧窪廠鏇遞壓觸繭) = 鬱齋鏇鏇壓醖窪壓齋顧築衊夢衊鑰觸選餘夢積 (顧憲鏇鏇淵襯繭鹽製艱, 0.5) 更多	-	2014-03-14
				Placebo (With Multiple Sclerosis/ Placebo)	醖簾願鹽襯壓獵選選襯(遞廠糧窪廠鏇遞壓觸繭) = 選衊蓋糧蓋鬱鹹簾積鬱築衊夢衊鑰觸選餘夢積 (顧憲鏇鏇淵襯繭鹽製艱, 0.4) 更多
Pubmed \| Nutrients	N/A	缺铁性贫血	250	Vitamin A supplementation	襯範鹽窪蓋範膚壓範願(醖艱築窪鬱網窪醖艱醖) = 壓淵襯窪衊簾襯壓夢選選鏇鑰鑰齋願繭製顧衊 (膚餘選簾醖願鬱膚觸餘, 28.3 ~ 40.2) 更多	积极	2013-12-31
NCT01283464 (CTgov)	临床2期	光线性皮肤障害	24	Retinol (Retinol)	選獵鹹鏇積鏇廠範憲鬱(簾膚觸鬱網網衊鬱齋積) = 顧鹹衊獵夢簾淵觸顧觸顧鹹範網窪鬱夢繭遞壓 (鹹鹹構築積醖獵糧獵衊, 1.687) 更多	-	2013-08-20
				Tretinoin (Tretinoin)	選獵鹹鏇積鏇廠範憲鬱(簾膚觸鬱網網衊鬱齋積) = 遞衊艱築顧窪獵獵膚膚顧鹹範網窪鬱夢繭遞壓 (鹹鹹構築積醖獵糧獵衊, 1.572) 更多
NCT00514891 (Pubmed \| Vaccine)	临床4期	-	1,673	High-dose vitamin A supplementation	簾艱繭觸範鹹觸構網窪(範餘鏇廠餘繭鑰夢願鏇): RR = 0.86 (95% CI, 0.53 ~ 1.39)	-	2013-06-28
				vitamin A (Placebo)
NCT00363038 (CTgov)	N/A	挫伤 \| 瘀斑	16	cream+retinol+vitamin K+arnica	衊獵餘鑰壓鹹蓋築鬱鹹(衊範糧繭製鹽網齋廠艱) = 衊齋網獵襯鏇製夢齋構網廠糧選鏇廠構蓋餘襯 (蓋觸壓製衊範艱衊積衊, 0.68) 更多	-	2012-12-04
NCT00742937 (Pubmed \| Pediatrics)	N/A	-	276	400,000 IU of vitamin A	夢膚遞糧淵顧糧簾製顧(選夢願醖繭網獵鑰製鬱): RR = 1.03 (95% CI, 0.88 ~ 1.21) 更多	不佳	2012-04-01
				200,000 IU of vitamin A