ASP-7373(ASP-7373) - _专利_临床

Phase 2 Observer-Blind, Randomized Trial to Evaluate the Immunogenicity and Safety of PanBlok at Three Dose Levels Adjuvanted With a Stable Oil-in-Water Emulsion Compared With PanBlok Without Adjuvant in Healthy Adults Aged 18 to 49 Years

The purpose of this study is to investigate the safety and immunogenicity of a recombinant hemagglutinin (rHA) influenza vaccine derived from A/Indonesia/05/2005 (H5N1) administered at 3 dose levels in adjuvanted (SE) rHA formulations and 1 dose levels in an un-adjuvanted rHA formulation.

开始日期2012-05-01

申办/合作机构

Protein Sciences Corp.

NCT01450579

/ Completed临床2期

Phase II Study of ASP7373 Evaluation of Immunogenicity and Safety of ASP7373 in Healthy Adults

This trial is to investigate the clinically recommended dosage for ASP7373 based on the comparison of the immunogenicity and safety among the three doses of ASP7373 in healthy adults.

开始日期2011-07-01

申办/合作机构

UMN Pharma, Inc.

NCT01147068

/ Completed临床1/2期

A Two-Part Placebo-Controlled Evaluation of the Safety and Immunogenicity of an A/Indonesia/5/05 Recombinant Hemagglutinin Influenza H5N1 Vaccine With and Without Glucopyranosyl Lipid A (GLA-SE) in Healthy Adults 18-49

The purpose of this study is to investigate the safety and immunogenicity of a recombinant hemagglutinin (rHA) influenza vaccine derived from A/Indonesia/05/2005 (H5N1) administered at 4 dose levels in adjuvanted (GLA-SE) rHA formulations and 2 dose levels in unadjuvanted rHA formulations.

开始日期2010-06-01

申办/合作机构

Protein Sciences Corp.

100 项与 ASP-7373 相关的临床结果

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100 项与 ASP-7373 相关的转化医学

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100 项与 ASP-7373 相关的专利（医药）

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100 项与 ASP-7373 相关的药物交易

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研发状态

10 条进展最快的记录,

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适应症	最高研发状态	国家/地区	公司	日期
流感病毒感染	临床2期	日本	UMN Pharma, Inc.	2009-10-01
甲型流感病毒感染	临床1期	澳大利亚	Vaxine Pty Ltd.	2017-10-12

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


NCT01612000 (PSC25, CTgov)	临床1/2期	流感病毒感染	341	rHA adjuvant+PanBlok (PanBlok 15µg in 2% SE)	築壓夢廠鑰顧廠夢壓夢 = 簾鹽築遞遞顧鏇糧網鹹齋願餘選鹹構鏇鑰築齋 (顧窪鹹襯鹽遞艱鹽鹹製, 餘醖願夢築製齋範鏇網 ~ 廠衊製鑰願廠鬱簾艱壓) 更多	-	2015-11-25
				rHA adjuvant+PanBlok (PanBlok 3.8µg in 2% SE)	築壓夢廠鑰顧廠夢壓夢 = 鏇夢壓積網鏇鏇衊繭遞齋願餘選鹹構鏇鑰築齋 (顧窪鹹襯鹽遞艱鹽鹹製, 憲構簾壓淵鹹襯遞繭齋 ~ 窪鹹鑰夢蓋艱簾積鑰觸) 更多
NCT01147068 (CTgov)	临床1/2期	流感病毒感染	392	0.5mL Intramuscular Injection (Placebo)	鹹膚簾餘鏇壓顧鏇鏇鹹 = 構廠艱繭製選齋壓選製壓鑰鑰醖窪廠憲夢觸獵 (網蓋獵壓淵壓餘築鹹襯, 醖鬱製齋網窪獵蓋獵簾 ~ 憲鹹構遞獵鑰獵願夢築) 更多	-	2012-11-26
				0.5mL Intramuscular Injection (PanBlok 135µg No Adjuvant)	鹹膚簾餘鏇壓顧鏇鏇鹹 = 淵鏇觸遞膚窪鏇顧醖憲壓鑰鑰醖窪廠憲夢觸獵 (網蓋獵壓淵壓餘築鹹襯, 選構簾鏇繭壓醖醖積顧 ~ 遞願襯齋獵繭觸糧鬱夢) 更多