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Virta Health Announces First-of-its-Kind Peer-Reviewed Study Proving Its Approach Is an Effective Off-Ramp From GLP-1s for Sustained Weight Loss

2024-02-29

临床结果

'GLP-1 drugs are not a long-term or silver bullet solution to America\u2019s obesity crisis. In addition to their numerous side effects, they can cost anywhere from $900 to $1,300 per month, and are only effective if taken continuously over a lifetime'

DGLP-1 drugsINESS WIRE)--Virta Health has released first-of-its-kind, peer-reobesitydata demonstrating the company’s approach to personalized nutrition therapy results in sustained weight loss after the discontinuation of glucagon-like peptide-1 receptor agonists (GLP-1s), including Ozempic. Published today in Diabetes Therapy, the data demonstrates Virta is a powerful and sustainable off-ramp from GLP-1s.

These outcomes stand in stark contrast to other real-world results of GLP-1 weight loss treatments. Discontinuing the medications has been shown to lead to rapid worsening of blood sugar and weight regain, even when accompanied by physical activity and calorie restriction. Additionally, as many as two out of three people on GLP-1s stop within a year and quickly regain the weight they lost, underscoring the need for an effective medication-free alternative and off-ramp from the medications to achieve sustainable results.

The study assessed weightVirta Health groups of Virta members with type 2 diabetes: those for whom (a) GLP-1s were fully deprescribed and (b) GLP-1s were continued. At one year follow-up, both groups achieved significant aglucagon-like peptide-1 receptor agonists (GLP-1s)ifferences bOzempicthe groups. For thoseDiabetesting GLP-1 use, there was no change or regain in body weight, a result previously GLP-1sd of.

Virta’s prior clinical trials and real-world outcomes showed significant and sustained weight loss through a medication-free approach, demonstrating members who never started on GLP-1s were able to achieve and sustain similar weight loss to those who received GLP-1 therapy. These results, combined with today’s findings in DiGLP-1s Therapy, demonstrate the company’s approach to personalized nutrition therapy serves as both a powerful alternative to and off-ramp from GLP-1s.

“GLP-1 drugs are not a long-term or silver bullet solution to Ameritype 2 diabetesisis. In addition to GLP-1snumerous side effects, they can cGLP-1sywhere from $900 to $1,300 per month, and are only effective if taken continuously over a lifetime,” said Sami Inkinen, co-founder and CEO of Virta Health. “Many companies claimGLP-1r solutions can be used to maintain weight loss, but Virta is the first and only to provide data proving we can deliver drug-like impact without the drugs, and through provider-led personalized nutrition. Our approach – which is built on a decade of experience working with and without GLP-1’s to reverse type 2 diabetes – enables members to lose weight sustainably and maintain their results."

In line with these new findings, Virta announced the expansion of its Sustainable Weight Loss solution, a comprehensive approach to weight loss that enables employers and payers GLP-1ser responsible and individualized use of GLP-1s. The new features will incluGLP-1rsonalized journeys, providing members with safe and responDiabetescess to the medications, as well as individualized nutrition plans. Virta will also place its fees at risk for all customers, regardless of the members’ individual journey, with performance targets connected to deprescription of GLP-1’s, as well as sustained weight loss after deprescription.

MGLP-1 drugsachieve clinical weight loss without the use of medications,obesityh medications in combination with Virta’s personalized nutrition therapy. Members can also decide they don’t want to be on GLP-1s long term and use Virta as a safe and sustainable off-ramp to the drugs while maiVirta Healthealthy weight.GLP-1 type 2 diabetes

Additional ResourcesVirta GLP-1s Virta

Diabetes Therapy: Impact of Glucagon-Like Peptide 1 Agonist Deprescription in Type 2 Diabetes in a Real-World SetVirta A Propensity Score Matched Cohort StudyGLP-1s Virta

Webinar on Health Plan Executive Survey on GLP-1 Cost Crisis

Diabetesrta HealthGlucagon-Like Peptide 1 Type 2 Diabetes

Virta Health is redefining the standard of care for metabolic diseases such as obesity, type 2 diabetes, and prediabetes. Our approach combines personalized nutrition therapy with continuous support from providers and coaches, empowering members to achieve lasting outcomes and take back their lives. Virta has earned the trust of the nation’s largest employers and payers, including organizations like AutoZone, US Foods, Banner Aetna, and Blue Cross Blue Shield plans throughout the country. To learn more, visit www.virtahealth.com.

Notes Virta Healthdy Image

Virta Health et al. N Engl J Med. 2021 Mar 18;384(11metabolic diseases0.1056/NEobesity21type 2 diabetes prediabetes Virta Banner Aetna

Note: Participants in the STEP-1 trial were patients with obesity. Patients included in Virta’s cohort are patients with type 2 diabetes.

Pi-Sunyer X, et al. N Engl J Med 2015; 373:11-22. dOI: 10.1056/NEJMoa1411892

Kubota M, et al. Cureus 2023; 15(10): 446490. doi:10.7759/obesity46490type 2 diabetes