The latest Pathway grants will fund two projects: "Investigating Mitochondrial Dysfunction as an Early Pathogenic Mechanism of Primary Tauopathies, Using MAPT Splicing Mutation iPSC-organoids" by Dr. Kathryn Bowles, and "Defining the Unique Immunogenetic Landscape of PSP Compared to Related Dementias" by Dr. Jessica Rexach. The newest Pipeline grants will fund two projects: "Blood-based Fingerprints of Neuroinflammation in People with PSP and CBD" by Dr. Maura Malpetti, and "Characterization of Plasma-derived Extracellular Vesicle Proteomics for Biomarker Development of PSP and CBD" by Dr. Yang You. "Together, these grants reflect CurePSP's commitment to funding junior investigators working in high-priority research areas that will help advance our understanding and treatment of PSP and CBD," said Dr. Jennifer Brummet, associate director of scientific affairs and partnerships at CurePSP. "There is a critical need to improve our understanding of PSP and CBD and to improve diagnosis, and these grants will help move the field forward." About CurePSP's Research Grants
Pathway and Pipeline Grants provide seed funding to support innovative projects focused on the fundamental neurobiology and mechanisms of tauopathies ("Pathway"), and translational projects focusing on new therapeutics and biomarkers for tauopathies ("Pipeline"). The next deadline for Pathway and Pipeline Grant applications is March 28, 2024. Learn more about our research grants here. CurePSP is the leading nonprofit organization dedicated to the awareness, care and cure for three neurodegenerative diseases: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and multiple system atrophy (MSA). As a catalyst for new treatments and a cure, CurePSP establishes important partnerships and funds critical research internationally. Through its advocacy and support efforts, CurePSP enhances education, care delivery and quality of life for people living with PSP, CBD and MSA and their families. Science, community and hope are at the heart of CurePSP's mission and all its services. CurePSP is a registered 501(c)(3) charity within the United States (EIN: 52-1704978). For more information, please visit www.curepsp.org. Executive Director and Chief Science Officer