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NRx Pharmaceuticals (NASDAQ:NRXP) Publishes Shareholder Update Letter

2024-07-01

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Potential paths to revenue and profitability in 2025

RADNOR, Pa., July 1, 2024 /PRNewswire/ -- NRx Pharmaceuticals, Inc. (Nasdaq: NRXP) ("NRx Pharmaceuticals", the "Company"), a clinical-stage biopharmaceutical company, today announced that the Company posted a new Shareholder Update Letter on its website NRx Shareholder Update and further invites interested parties to subscribe to their email alert service to stay up to date on company's progress here: NRx Email Alerts . (Note: not all updates will be included in a Press Release in the future).

Today's update highlights potential paths to profitability for NRx in 2025. Key items include:

HOPE Therapeutics, Inc. (PRNewsfoto/NRx Pharmaceuticals, Inc.)

HOPE Therapeutics, Inc.from operatioNRx Pharmaceuticals, Inc.anded interventional psychiatry clinics

Potential 2025 Revenue from sales of NRX-HOPE Therapeutics based on an FDA New Drug Application approval

Potential 2025 Revenue from sales of NRX-100 as aKetamineproved product for the sub-population of people with suicidal bipolar depression and akathisia

Please see the full letter for a detaNRX-101scussion of these and other topicssuicidal bipolar depression

Please subscribe to the Company's email for future updates. NRX Email Alerts Not all of these will be the subject of a Press Release in the future.

About NRx Pharmaceuticals

NRx PhNRx Pharmaceuticalsclinical-stage biopharmaceutical company developing therapeutics based on its NMDA platform for the treatment of central nervous system disorders, specifically suicidal bipolar depression, chronic pain and PTSD. The Company is developing NRX-101, an FDA-designated investigational Breakthrough Therapy for suicidal treatment-resistant bipolar depression and chronic pain. NRx has partnered with Alvogen and Lotus around the development and marketing of NRX-101 for the treatment of suicidal bipolar depression. NRX-101 additionally has potential to act as a non-opioid treatment for chronic pain, as well as a treatment for complicated UTI.

NRx Pharmaceuticalsnounced plans to submit a New Drug Application for NRX-100 (IV ketamine), in the treatment of suicidal depression, basecentral nervous system disordersclinical trialssuicidal bipolar depressioneschronic painationPTSDnstitutes of Health and newlNRX-101ned data from French health authorities, licensed under a data sharing agreement. NRx was awarded Fast Track Desichronic paindeNRxopment of ketamine (Alvogen) by LotusS FDA as part of a protocol to treat patiNRX-101th acute suicidality.suicidal bipolar depression NRX-101 chronic pain complicated UTI

NRxut HOPE Therapeutics, Inc.NRX-100 ketamine suicidal depression National Institutes of Health NRx ketamine NRX-100 US FDA

HOPE THOPE Therapeutics, Inc.hopetherapeutics.com) is a Specialty Pharmaceutical Company, wholly-owned by NRX Pharmaceuticals, focused on development and marketing of an FDA-approved form of intravenous ketamine for the treatment of acute suicidality and depression, together with a digital therapeutic-enabled platform designed to augment and preserve the clinical benefit of NMDA-targeted drug therapy.

HOPE Therapeutics, Inc.d-Looking StatementsNRX Pharmaceuticals ketamine acute suicidality depression

The information contained herein includes forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. These statements include, among others, statements regarding the proposed public offering and the timing and the use of the proceeds from the offering. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as "may," "will," "should," "would," "expect," "plan," "believe," "intend," "look forward," and other similar expressions among others. These statements relate to future events or to the Company's future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects the Company's current views with respect to future events and is subject to these and other risks, uncertainties and assumptions relating to the Company's operations, results of operations, growth strategy and liquidity. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company's most recent Annual Report on Form 10-K and other filings with the Securities and Exchange Commission. Investors and security holders are urged to read these documents free of charge on the SEC's website at http://www.sec.gov. Except as may be required by applicable law, The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE NRx Pharmaceuticals, Inc.