Novelion Therapeutics, Inc.

VANCOUVER, British Columbia, March 10, 2023 (GLOBE NEWSWIRE) -- Novelion Therapeutics Inc. (“Novelion” or the “Company”) by Alvarez & Marsal Canada Inc., Novelion’s liquidator (the “Liquidator”) today announced that Novelion has concluded the implementation of its plan of liquidation and distribution (the “Plan”) by winding down and dissolving the Company (the “Dissolution”). The Dissolution followed the completion of all remaining steps of the Company’s Plan, in accordance with the Orders of the Supreme Court of British Columbia (the “B.C. Court”). As previously announced, the Liquidator obtained approval from the B.C. Court to proceed with the Dissolution of the Company after a final distribution. Certain releases and approvals of the Liquidator’s fees and disbursements were also granted by the B.C. Court. The final distribution was comprised of approximately US$2.47 million (US$0.125/share), representing the aggregate of the cash remaining in Novelion, including the proceeds from the sale of the remaining American depository receipts of Amryt Pharma plc, less expenses incurred or to be incurred through the completion of the Company’s statutory liquidation, and was made in March 2022, On January 25, 2022, the United States Bankruptcy Court for the Southern District of New York (the “US Court”) granted an Order closing the proceedings of Novelion under Chapter 15 of the United States Bankruptcy Code. The Liquidator will be seeking its discharge from the B.C. Court following completion of the Dissolution. Any interested parties should visit www.alvarezandmarsal.com/novelion for further information about Novelion, the Liquidation, the Dissolution and related matters. Cautionary Information Regarding the Company’s Securities As of the effective date for the Company’s liquidation, being January 16, 2020 (the “Effective Date”), the Company’s transfer agent closed the Company’s stock transfer books and discontinued recording transfers, and registered shareholders were no longer able to transfer ownership of their shares. All distributions made in the Liquidation, were made only to registered shareholders as of the Effective Date, and beneficial holders of common shares were entitled to receive any distributions only through and from the applicable registered holder of their shares. Shareholders whose shares in Novelion were held in a brokerage firm or with a securities dealer, trust company, bank or another similar organization, are encouraged to reach out to their broker, dealer, trust, bank or other agent with any questions relating to the processes or requirements for receiving any such distributions. The Company believes, but cannot assure, that trading in the Company’s common shares was suspended or otherwise ceased as of the Effective Date or shortly thereafter. Contact: Nishant VirmaniAlvarez & Marsal Canada Inc.nvirmani@alvarezandmarsal.comwww.alvarezandmarsal.com/novelion

The NEW Amarin and NEW Board is On the Right Track – Leading Independent Experts, ISS and Glass Lewis, Agree that Sarissa Representation is Not Warranted Sarissa’s Misguided Campaign to Remove Amarin’s Chairman and Gain De Facto Board Control Would be Detrimental to Shareholder Value Sarissa Continues to Spread Misinformation at the Expense of All Amarin Shareholders in its Self-Serving Attempt to Get on the Board Deadline to Submit Votes for ADS Holders is 3 PM GMT (10 AM ET) on February 22, 2023, and 3 PM GMT (10 AM ET) on February 24, 2023, for Holders of Ordinary Shares DUBLIN, Ireland and BRIDGEWATER, N.J. , Feb. 17, 2023 (GLOBE NEWSWIRE) -- The Amarin Corporation plc (NASDAQ: AMRN) (“Amarin” or the “Company”) Board of Directors today issued the following statement reiterating to shareholders its recommendation to vote on the WHITE proxy card “AGAINST” all of Sarissa’s harmful proposals ahead of the General Meeting of Shareholders, which is scheduled to be held on February 28, 2023. Shareholders of record as of January 23, 2023, will be entitled to vote at the meeting. For ADS holders, the deadline to submit votes is 3 PM GMT (10 AM ET) on February 22, 2023, and for holders of ordinary shares, the deadline is 3 PM GMT (10 AM ET) on February 24, 2023. The Amarin Board has one critical message for our shareholders: Amarin is at an inflection point, where upcoming pricing and reimbursement negotiations and decisions will chart the future for the Company, including ensuring M&A is a viable option. Our refreshed Board are the change agents the Company needs and have actively positioned the business to turn Amarin around and drive near- and long-term value. As leading independent proxy advisory firms Institutional Shareholder Services (“ISS”) and Glass Lewis & Co (“Glass Lewis”) recognized in their vote recommendations for Amarin’s WHITE proxy card “AGAINST” Sarissa’s proposals, the new and refreshed Board has already made significant changes over the last 18 months. Meanwhile, Sarissa has failed to make a compelling case for change. ISS and Glass Lewis’s recommendations are important third party endorsements that Amarin has the RIGHT strategy, RIGHT team and RIGHT Board to drive near- and long-term value. Here is why: Critical expertise is needed and already on the Board today. Our Board is intimately involved in pricing and reimbursement discussions, including Chairman Per Wold-Olsen. Depriving the Company of essential advice and experience – by removing Mr. Wold-Olsen and adding seven underqualified candidates who have little to no expertise in this area – would be detrimental. Theoretical “shareholder representation” will not make up for this massive loss of experience and practical know-how. Additionally, nearly doubling the size of the Board for a company of our size does not make sense, and if anything, would put the Company at risk at a critical time. Mr. Wold-Olsen is an essential guiding force. He has brought his wealth of experience to bear in every area of Amarin’s business. Mr. Wold-Olsen has direct relationships with European regulators that he is leveraging to benefit Amarin as we navigate the complexities of pricing and reimbursement negotiations and he works directly with management daily, demonstrating his unwavering commitment to Amarin’s success. The future of Amarin hinges on its ability to negotiate successful pricing in Europe – and Mr. Wold-Olsen is central to this effort. Sarissa is not. Amarin’s Board is superior to Sarissa’s slate in every critical area. Amarin’s refreshed Board brings more than 260 years of critical expertise across international, in particular European, cardiovascular and related product launches, and healthcare investment which has been vital to Amarin’s early success. Sarissa’s underqualified nominees, on the other hand, collectively lack critical understanding of operating a pharma company and have minimal experience with European drug launches, pricing and reimbursement and commercial expertise. Amarin has taken proactive and decisive action to succeed and drive value. The refreshed Board, alongside the new management team, have taken swift and proactive action. These steps have contributed to substantial progress in a short period of time across all facets of the business – strategic, operational and financial – and are reflected in Amarin’s performance in 2022 and early 2023. Sarissa has an abysmal track record. We understand our shareholders’ frustration with Amarin’s stock price today, but it is critical that our shareholders consider the facts when Sarissa is on boards: Median total shareholder return (“TSR”) at companies during the tenure of Sarissa nominated directors is NEGATIVE 24%1Companies that Sarissa excluded from its presentation have a median TSR of a staggering NEGATIVE 59%1In four instances, companies with Sarissa nominated directors LOST OVER 75% of their value1 The Amarin Board has been and continues to be 100% focused on advancing all of our shareholders’ best interests. Sarissa, on the other hand, purposefully provides shareholders with misinformation as part of its transparent attempt to do anything to get on the Board. Sarissa is only focused on serving its own self-interest at the expense of all Amarin shareholders. If Sarissa cannot be trusted to provide shareholders with the truth, why should it be trusted as a steward of shareholder value creation? The current Amarin Board is best equipped to guide the NEW Amarin and maximize shareholder value. We strongly urge all shareholders to consider what is at stake and vote “AGAINST” Sarissa’s harmful proposals on the WHITE proxy card. With Amarin’s February 28 General Meeting fast approaching, it is extremely important that you vote as soon as possible, no matter how many shares you own. Shareholders can switch their vote at any time by simply voting on the WHITE proxy card “AGAINST” all of Sarissa’s harmful proposals. Only the latest-dated proxy counts. Amarin shareholders who need assistance in voting their shares may call Amarin’s proxy solicitors: Morrow Sodali at (800) 662-5200 (toll-free) or (203) 658-9400 (collect) or Okapi Partners at (844) 343-2625 (toll-free) or (212) 297-0720 (international). Additional materials regarding the Board of Directors’ recommendations for the General Meeting can be found at www.voteamarin.com. Advisors J.P. Morgan is acting as financial advisor. Ropes & Gray LLP and Goodwin Procter LLP are acting as legal advisors to the Company. About Amarin Amarin is an innovative pharmaceutical company leading a new paradigm in cardiovascular disease management. From our foundation in scientific research to our focus on clinical trials, and now our commercial expansion, we are evolving and growing rapidly. Amarin has offices in Bridgewater, New Jersey in the United States, Dublin in Ireland, Zug in Switzerland, and other countries in Europe as well as commercial partners and suppliers around the world. We are committed to increasing the scientific understanding of the cardiovascular risk that persists beyond traditional therapies and advancing the treatment of that risk. Forward-Looking Statements This press release contains forward-looking statements which are made pursuant to U.S. federal securities law. These forward-looking statements are not promises or guarantees and involve substantial risks and uncertainties. A further list and description of these risks, uncertainties and other risks associated with an investment in Amarin can be found in Amarin’s filings with the U.S. Securities and Exchange Commission, including Amarin’s annual report on Form 10-K for the full year ended 2021, and Amarin’s quarterly reports on Form 10-Q for the quarters ended March 31, 2022, June 30, 2022, and September 30, 2022, and its other filings. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. Amarin undertakes no obligation to update or revise the information contained in its forward-looking statements, whether as a result of new information, future events or circumstances or otherwise. Amarin’s forward-looking statements do not reflect the potential impact of significant transactions the company may enter into, such as mergers, acquisitions, dispositions, joint ventures or any material agreements that Amarin may enter into, amend or terminate. Amarin Contact Information Investor Inquiries:Lisa DeFrancescoInvestor Relations Amarin Corporation plcinvestor.relations@amarincorp.com (investor inquiries) Media Inquiries:Mark MarmurCorporate Communications, Amarin Corporation plcPR@amarincorp.com (media inquiries) Or Steve Frankel / Andi Rose / Tali EpsteinJoele Frank, Wilkinson Brimmer Katcher212-355-4449 1 Statistics are based on the total stock return of companies where a Sarissa-affiliated director held tenure as a board member, from the market date immediately preceding their first date in-service, to the final date of their service or February 3, 2023. Companies with Sarissa-affiliated directors include VIVUS, Inc., Emmaus Life Sciences, Inc., ARIAD Pharmaceuticals, Inc., Aegerion Pharmaceuticals, Inc., The Medicines Company, Novelion Therapeutics, Inc., Bioverativ, Inc., Innoviva, Inc., Regulus Therapeutics, Inc., Armata Pharmaceuticals, Inc., Ironwood Pharmaceuticals, Inc., and Alkermes, Plc

Letter Underscores the Change That is Being Led by Amarin’s New Board Highlights Sarissa’s Track Record of Value Destruction in the Healthcare Space Sarissa Continues to Mislead Shareholders by Distorting Facts and Promoting Misinformation DUBLIN, Ireland and BRIDGEWATER., N.J., Feb. 09, 2023 (GLOBE NEWSWIRE) -- Amarin Corporation plc (NASDAQ: AMRN) (“Amarin” or the “Company”) today announced that it has mailed a letter to shareholders in connection with the General Meeting of Shareholders urging shareholders to vote “AGAINST” all proposals on the WHITE proxy card. The General Meeting of Shareholders is scheduled to be held on February 28, 2023, and shareholders of record as of January 23, 2023, will be entitled to vote at the meeting. The full text of the letter being mailed to shareholders can be found at www.voteamarin.com and follows: Time is short and the facts are clear. Act today to ensure that the Amarin Board and management team are best positioned to continue executing our transformation plan and deliver near- and long-term value for you. Scan this QR code to learn more about why you should vote AGAINST Sarissa’s harmful proposals on the WHITE proxy card today. Please follow the instructions on the enclosed WHITE proxy card and vote by telephone, internet or mail. For ADS holders, the deadline to submit your vote is 3 PM GMT (10 AM ET) February 22, 2023, and for holders of ordinary shares, the deadline is 3 PM GMT (10 AM ET) February 24, 2023. 1. We are a NEW Amarin: NEW Board, NEW Management Team and NEW Strategy. The Amarin of today is a profoundly different company than 18 months ago. We recognized change was needed, and today, this new team is executing a turnaround strategy to drive value with the oversight of a purpose-built Board. Amarin is making early progress. Now is the time for us to build on our momentum to turn the Company around and create value for our shareholders. It is not the time to remove our new, highly qualified Chairman, Per Wold-Olsen, nor is it the time to nearly double the size of the Board with underqualified candidates as part of Sarissa’s self-serving attempt to get on the Board. 2. Sarissa has a track record of value destruction. Sarissa claims it has created value in the healthcare space, but the facts show the opposite: The median total shareholder return (“TSR”) at companies during the tenure of Sarissa-nominated directors is NEGATIVE 24%.1 The companies that Sarissa excluded from its presentation have a median TSR of a staggering NEGATIVE 59%.1 In four instances, companies with Sarissa-nominated directors LOST OVER 75% of their value.1 3. Amarin has the right Board and team to maximize shareholder value. We don’t need Sarissa to do it. When it comes to M&A, you should know that the Amarin Board is committed to evaluating any real opportunity that would maximize value for Amarin shareholders, including a sale of the Company. We specifically added M&A expertise to our Board – Adam Berger, who has extensive experience as a healthcare investment banker, including involvement in over 90 sales – as well as directors and a leadership team with extensive backgrounds at and relationships with large global pharma companies. Simply put, we don’t need Sarissa to maximize value. Sarissa’s latest presentation recycles its own slides, fails to address serious misstatements Amarin has pointed out and has released even more misinformation to mislead shareholders, including: Failing to address Sarissa’s abysmal record of destroying shareholder value. Continuing to compare Amarin to The Medicines Company, an irrelevant example when it comes to M&A and implementing a subscription model. Perpetuating misinformation regarding the Amarin Board’s comments on its refreshment process – alleged remarks that were never made. Implying that four of Sarissa's seven candidates were involved in key financial and operational decisions at The Medicines Company. The ONLY Sarissa representative to serve on the Board of The Medicines Company was Alex Denner, and he is not included on Sarissa’s slate at Amarin. Deliberately and knowingly misrepresenting established U.K. law regarding voting deadlines and voting deadlines set by Amarin’s ADS depositary. Amarin does not set these deadlines – U.K law and the depositary do. Vote on the WHITE proxy card “AGAINST” Sarissa’s harmful proposals today. We encourage you to visit our website www.voteamarin.com for more details on our plan and FAQs. YOUR VOTE IS IMPORTANT! If you have any questions, or need assistance in voting your ADS or shares on the WHITE proxy card, please call our proxy solicitor: Morrow Sodali LLC509 Madison Avenue, 12th FloorNew York, NY 10022Okapi Partners LLC1212 Avenue of the Americas, 17th FloorNew York, NY 10036 Toll-free: 1 (800) 662-5200Collect: 1 (203) 658-9400Email: AMRN@info.morrowsodali.comToll-free: 1 (844) 343-2625International: 1 (212) 297-0720Email: info@okapipartners.com Advisors J.P. Morgan is acting as financial advisor. Ropes & Gray LLP and Goodwin Procter LLP are acting as legal advisors to the Company. About Amarin Amarin is an innovative pharmaceutical company leading a new paradigm in cardiovascular disease management. From our foundation in scientific research to our focus on clinical trials, and now our commercial expansion, we are evolving and growing rapidly. Amarin has offices in Bridgewater, New Jersey in the United States, Dublin in Ireland, Zug in Switzerland, and other countries in Europe as well as commercial partners and suppliers around the world. We are committed to increasing the scientific understanding of the cardiovascular risk that persists beyond traditional therapies and advancing the treatment of that risk. Forward-Looking Statements This press release contains forward-looking statements which are made pursuant to U.S. federal securities law. These forward-looking statements are not promises or guarantees and involve substantial risks and uncertainties. A further list and description of these risks, uncertainties and other risks associated with an investment in Amarin can be found in Amarin’s filings with the U.S. Securities and Exchange Commission, including Amarin’s annual report on Form 10-K for the full year ended 2021, and Amarin’s quarterly reports on Form 10-Q for the quarters ended March 31, 2022, June 30, 2022, and September 30, 2022, and its other filings. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. Amarin undertakes no obligation to update or revise the information contained in its forward-looking statements, whether as a result of new information, future events or circumstances or otherwise. Amarin’s forward-looking statements do not reflect the potential impact of significant transactions the company may enter into, such as mergers, acquisitions, dispositions, joint ventures or any material agreements that Amarin may enter into, amend or terminate. Amarin Contact Information Investor Inquiries:Lisa DeFrancescoInvestor Relations Amarin Corporation plcinvestor.relations@amarincorp.com (investor inquiries) Media Inquiries:Mark MarmurCorporate Communications, Amarin Corporation plcPR@amarincorp.com (media inquiries) Or Steve Frankel / Andi Rose / Tali EpsteinJoele Frank, Wilkinson Brimmer Katcher212-355-4449 1 Statistics are based on the total stock return of companies where a Sarissa-affiliated director held tenure as a board member, from the market date immediately preceding their first date in-service, to the final date of their service or February 3, 2023. Companies with Sarissa-affiliated directors include VIVUS, Inc., Emmaus Life Sciences, Inc., ARIAD Pharmaceuticals, Inc., Aegerion Pharmaceuticals, Inc., The Medicines Company, Novelion Therapeutics, Inc., Bioverativ, Inc., Innoviva, Inc., Regulus Therapeutics, Inc., Armata Pharmaceuticals, Inc., Ironwood Pharmaceuticals, Inc., and Alkermes, Plc.