Delving into the Latest Updates on 上海紫源制药有限公司 with Synapse

概览

排名前五的药物类型	数量

小分子化药	1

关联

1

项与上海紫源制药有限公司相关的药物

Dimefline Hydrochloride

盐酸二甲弗林

靶点-

作用机制-

在研机构

上海紫源制药有限公司 [+1]

原研机构

上海医药集团股份有限公司

在研适应症

呼吸功能不全

非在研适应症-

最高研发阶段批准上市

首次获批国家/地区-

首次获批日期-

100 项与上海紫源制药有限公司相关的临床结果

登录后查看更多信息

0 项与上海紫源制药有限公司相关的专利（医药）

登录后查看更多信息

2

项与上海紫源制药有限公司相关的文献（医药）

Shanghai Yiyao

Total synthesis of regadenoson

作者: Luo, Jianfei ; Zhang, Zhigang ; Liu, Wei

Objective: To improve the process for the synthesis of regadenoson and its quality.Methods: Regadenoson was synthesized from 2-chloroadenosine via etherification with tert-butyldimethylchlorosilane and reacted with hydrazine hydrate to give 2′,3′,5′-tri-(tert-butyldimethylsiyl)oxy-2-hydrazinyl adenosine, which was cyclized with Et 2-formyl-3-oxopropanoate, and finally the protecting groups were removed.Results: The purity and yield of regadenoson were improved up to 99.0% and 47.2%, resp.Conclusion: The improved process can be easily operated with high yield and quality, which is suitable to industrial production

Zhongguo Yiyao Gongye Zazhi

Synthesis of vitamin K with different ratio of cis/trans isomers

作者: Zhang, Zhigang

Vitamin K₁ with different ratio of cis/trans isomers was synthesized from natural phytol via bromination with phosphorus tribromide in the presence of different content of water to get different ratio of (E/Z)-isomeric phytyl bromide, followed by condensation with cyclopentadiene-menadione adduct and retro-Diels-Alder reaction.

100 项与上海紫源制药有限公司相关的药物交易

登录后查看更多信息

100 项与上海紫源制药有限公司相关的转化医学

登录后查看更多信息