Lithuanian University of Health Sciences

Advanced Dental Center Expands Full-Mouth Restoration and Gum Disease Treatment with Modern Tools Norwalk, CT / USA, June 16, 2025 (GLOBE NEWSWIRE) -- Norwalk, CT — Advanced Dental Center in Norwalk, Connecticut, led by Dr. Elad Yossefi and Dr. Tal Yossefi, is introducing new technology-driven services to improve patient care. Located on Main Avenue, the practice is focusing on procedures such as full-mouth restoration, laser-assisted periodontal therapy, and Invisalign, with an emphasis on clinical precision and patient experience. Drs. Elad and Tal Yossefi, honored as America’s Best Dentists 2023 at Advanced Dental Center in Norwalk, CT. Dr. Tal Yossefi, a graduate of the University of Pennsylvania, and Dr. Elad Yossefi, who earned his degree from NYU and the Lithuanian University of Health Sciences, bring international training to their practice. Their approach integrates digital diagnostics and design tools to customize treatment plans for each individual. Among the expanded services is full-mouth restoration, a procedure combining crowns, veneers, implants, and bite realignment. The center employs digital scans, facial mapping, and smile design software to support outcomes that are both functional and aesthetic. The clinic has also adopted LANAP® (Laser-Assisted New Attachment Procedure), an FDA-cleared technique used to treat advanced gum disease. This method utilizes laser technology to reduce discomfort and preserve healthy tissue, offering an alternative to traditional surgical procedures. To increase accessibility and reduce patient wait times, the center uses CEREC equipment, enabling same-day crown production without temporary fittings. For orthodontic treatment, the practice has achieved Gold Provider status with Invisalign®, using 3D planning and clear aligners to guide dental realignment. From pediatric care to complex oral rehabilitation, Advanced Dental Center is expanding its offerings with a focus on clinical transparency and patient-centered care. For more information, visit www.smilenorwalk.com or call (203) 364-5084. Media Contact: Eva Kavanagh Advanced Dental Center Norwalk adcnorwalk@gmail.com 1(203) 364-5084 Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

Scientists have revealed that low-frequency ultrasound influences blood parameters. The findings suggest that ultrasound's effect on haemoglobin can improve oxygen's transfer from the lungs to bodily tissues. The research was undertaken on 300 blood samples collected from 42 pulmonary patients. Research conducted by a team of scientists from Kaunas universities, Lithuania, revealed that low-frequency ultrasound influences blood parameters. The findings suggest that ultrasound's effect on haemoglobin can improve oxygen's transfer from the lungs to bodily tissues. The research was undertaken on 300 blood samples collected from 42 pulmonary patients. The samples were exposed to six different low-frequency ultrasound modes at the Institute of Mechatronics of Kaunas University of Technology (KTU). The changes in 20 blood parameters were registered using the blood analysing equipment at the laboratories of the Lithuanian University of Health Sciences (LSMU). For the prediction of ultrasound exposure, artificial intelligence, i.e. analysis of variance (ANOVA), non-parametric Kruskal-Wallis method and machine learning algorithms were applied. The calculations were made at the KTU Artificial Intelligence Centre. The use of non-pharmaceutical treatment improves oxygen circulation and reduces blood pressure KTU professors Vytautas Ostasevicius and Vytautas Jurenas say that the ongoing research papers are related to blood platelet aggregation. The research of the KTU team revealed that the ultrasound's impact on blood parameters is not limited to the platelet count -- it also affects red blood cells (RBC), which can result in better oxygen circulation and lowered blood pressure. "During exposure to low-frequency ultrasound, aggregated RBCs are dissociated into single RBCs, whose haemoglobin molecules interact with oxygen over the entire surface area of RBCs, which is larger than that of aggregated RBCs and improves oxygen saturation in blood. The number of dissociated single RBCs per unit volume of blood decreases due to the spaces between them, compared to aggregates, which reduces blood viscosity and affects blood pressure," explains Prof Ostasevicius, the Head of KTU Institute of Mechatronics. The scientists claim that the effect of ultrasound on the haemoglobin in RBCs was higher than its impact on platelet aggregation, which is responsible for blood clotting. Their findings have been supported by an additional analysis made at the LSMU Laboratory of Molecular Cardiology. "This means that low-frequency ultrasound can be potentially used for improving oxygen saturation in lungs for pulmonary hypertension patients. Keeping in mind the recent COVID-19 pandemic, we see a huge potential in exploring the possibilities of our technology further," says Prof Ostasevicius. Partnership between medical and engineering scientists In medicine, high-frequency ultrasound from 2 to 12 MHz is used for both diagnostic and therapeutic purposes. "Acoustic waves emitted by high-frequency ultrasound have a limited penetration depth into the body, so external tissues are more affected by high-frequency ultrasound than internal organs. Low-frequency ultrasound acoustic waves, penetrate deeper into the internal organs with a more uniform sound pressure distribution," explains Prof Jurenas. There are numerous applications for ultrasound in medical settings. "For example, focused ultrasonic waves are used to break kidney stones, and to kill cancer cells. Maybe ultrasound can be used to activate certain medications. Or, to alleviate the delivery of antibiotics to the inflamed areas?" says Prof J?r?nas. The technology used in the above-described study is only one illustration of many successful working partnerships between engineers and physicians. For example, just recently, the researchers of KTU Institute of Mechatronics have created the frame for immobilising the Gamma Knife radiosurgery patients at the Clinics of the Lithuanian University of Health Sciences. "We believe, that using the know-how of different areas one can achieve greater results," say KTU researchers about interinstitutional and interdisciplinary cooperation.

CÚRAM SFI Research Centre for Medical Devices researchers have published in Nature Communications a key study establishing a new pre-clinical model to develop clinically relevant treatments for heart attacks. This research resulted from an established collaboration of CÚRAM with European institutions in Italy (University of Milano-Bicocca), France (University of Paris Est Créteil), Sweden (University of Gothenburg) and Lithuania (Lithuanian University of Health Sciences). Heart attacks (myocardial infarction (MI)) occur due to an acute complication of coronary artery disease and are a major cause of global mortality. The two main types of heart attack are ST-elevation (STEMI) and Non-ST elevation (NSTEMI). A non-ST-elevation is a type of heart attack that usually happens when your heart's oxygen needs are unmet. This condition gets its name because it doesn't have an easily identifiable electrical pattern like with an ST elevation that can be read from an electrocardiogram (ECG). Currently, preclinical models of heart attack mimic only full-thickness STEMI and hence cater only for an investigation into therapeutics and interventions directed at the NSTEMI subset of heart attack. In this new study, researchers have developed a preclinical model of NSTEMI by adopting a novel surgical procedure that closely resembles the complexity of clinical cases in humans. Researchers validated the presented model by comparing it with an established method to achieve STEMIs. They performed a detailed analysis at the main acute and late time points after the induction of NSTEMI, at 7 and 28 days, respectively. Dr Paolo Contessotto and Dr Renza Spelat said: "Advanced analyses on the affected heart tissue highlighted a distinctive pattern of alterations in the tissue, especially in the sugar moieties (glycans) which compose cardiac cell membranes and extracellular matrix (the network of proteins and other molecules that surround, support, and give structure to cells and tissues in the body). Identifying such changes in molecular elements that can be accessed and treated with injectable drugs sheds light on how we can develop targeted pharmacological solutions to correct these changes." Professor Abhay Pandit, CÚRAM Scientific Director and senior author of the study, said: "There is a need in the field to adopt clinically relevant models to study NSTEMI pathophysiology and reveal its functional differences with STEMI induction. This new model will facilitate the translation of future research in the field, enabling the discovery of new clinically relevant treatments for patients." Dr Mark Da Costa, Clinical Investigator at CÚRAM and senior author of the study, said: "Currently, NSTEMI is the most common presentation of acute heart attack. The concern is that NSTEMI patients have lower in-patient (during their admission for the primary NSTEMI) and short-term mortality rates but significantly higher long-term mortality than those of STEMI patients. A Danish registry study of 8,889 patients showed that the 5-year mortality after NSTEMI was 16%, and another registry study highlighted a 10-year survival rate of only around 50%. To the best of our knowledge, there are currently no models that can reproduce both the functional and histological characteristics of NSTEMIs. This novel model may specifically serve as a preclinical foundation to study interventions that could combat the short and long-term effects of NSTEMI." Ends Notes for editors Link to complete manuscript: Nature Communications volume 14, Article number: 995 (2023) This study was funded by the European Commission funding under the AngioMatTrain 7th Framework Programme (Grant Agreement Number 317304) and by the research grant from Science Foundation Ireland (SFI) co-funded under the European Regional Development Fund under Grant Number 13/RC/2073 and13/RC/2073_P2 to A.P