Hospital General Universitario Gregorio Marañón

Based on the hypothesis that the strategy of using Closed-Blood Sampling Devices (CSBD, experimental group) compared to the usual practice (waste discard volume, control group), in critically ill adult patients, will decrease the amount of blood withdrawn for laboratory tests, we want to analyze the number of red blood cells (RBC) administered and arterial catheter-related adverse events (catheter-related bacteremia, catheter obstruction, CBSD malfunction, loss of arterial pressure waveform on the patient's bedside monitor) in both study groups, during ICU stay and up to a maximum of 21 days.

The aim of this multicenter non-controlled study is to develop a multivariable prediction model of pain/disability improvements in patients with full-thickness rotator cuff tears, after a physical therapy treatment based on therapeutic exercise and education.

The aim of this project is to set up a cross-sectional cohort study (France, Germany, The Netherlands, Poland, Spain, Switzerland, Italy, United Kingdom and Portugal) to assess the implementation of EACS guidelines for HDV-testing among PLWH with positive HbsAg and thereby evaluate the prevalence of HDV infection among HIV/HBV-coinfected in 2023, as well as corresponding risk factors. In addition to the testing itself, this study will also set up a cohort and databasee for future HDV studies among PLWH, including clinical, virological und laboratory parameters.
Analyze the rate of HDV-testing and evaluate the prevalence of HDV-infection by testing.
Evaluation of former screening of HDV by assessing existing data at study sites.
Determination of the HDV prevalence in European PLWH and HBV coinfection.
Setting up a database of all PLWH with HBV/HDV coinfection
Analysis of transmission risk factors for HDV coinfection
Asses the rate of HDV positive patients with ongoing HDV replication.
Define the liver disease state by APRI score, fibroscan, ultrasound and routine laboratory test results.