A Phase I/II Dose-escalation and Dose-expansion Study to Evaluate the Safety and Efficacy of FT-002 Subretinal Injection in Subjects With RPGR Gene Mutation-associated X-linked Retinitis Pigmentosa.

The aim of this study was to evaluate the safety, tolerability, and efficacy of one-time subretinal injection of FT-002 in male subjects (8-45 years of age) with RPGR (Retinitis Pigmentosa GTPase Regulator) gene mutation-associated X-linked retinitis pigmentosa, of XLRP. This study includes Phase I (dose escalation phase) and Phase II (dose expansion phase).

开始日期2024-04-01

申办/合作机构

Frontera Therapeutics, Inc.

NCT06492876

/ Recruiting临床1/2期

A Dose-escalation and Dose-expanded Phase I/II Clinical Study to Evaluate the Safety, and Efficacy of FT-003 in Subjects With DME

The goal of this clinical trial is to evaluate the safety, tolerability and efficacy of disposable vitreous injection of FT-003 in subjects with Diabetic Macular Edema (DME). The study was divided into two phases, Phase 1 dose escalation and Phase II dose expansion.

开始日期2023-11-15

申办/合作机构

Frontera Therapeutics, Inc.

NCT06492863

/ Recruiting临床1/2期

A Dose-escalation and Dose-expanded Phase I/II Clinical Study to Evaluate the Safety, and Efficacy of FT-003 in Subjects With Wet AMD

The goal of this clinical trial is to evaluate the safety, tolerability and efficacy of disposable vitreous injection of FT-003 in subjects with neovascular age-related Macular Degeneration (nAMD). The study was divided into two phases, Phase 1 dose escalation and Phase II dose expansion.

开始日期2023-08-15

申办/合作机构

Frontera Therapeutics, Inc.

[+3]

100 项与 Frontera Therapeutics, Inc. 相关的临床结果

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0 项与 Frontera Therapeutics, Inc. 相关的专利（医药）

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525

项与 Frontera Therapeutics, Inc. 相关的新闻（医药）

2025-09-27

·同写意

专访君实生物邹建军博士：多个肿瘤“王牌”蓄势待发

抗体药物偶联物临床3期CSCO会议免疫疗法引进/卖出

2025-09-24

·同写意

易慕峰生物IMC002 III期确证性临床研究全国启动丨会员动态

细胞疗法免疫疗法临床3期临床2期临床1期

2025-09-22

·同写意

皓元医药与迈威生物、英矽智能达成战略合作协议，高效推进ADC药物的创新和开发 | 会员动态

抗体药物偶联物引进/卖出

100 项与 Frontera Therapeutics, Inc. 相关的药物交易

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100 项与 Frontera Therapeutics, Inc. 相关的转化医学

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当前项目

药物(靶点)	适应症	全球最高研发状态

FT-001(Frontera) ( RPE65 )	2型利伯先天性黑朦症更多	临床2期
FT-003	糖尿病性黄斑水肿更多	临床1/2期
FT-004 ( factor IX )	血友病B 更多	临床1/2期
FT-002 ( RPGR )	X连锁视网膜色素变性更多	临床1/2期
FT-017 ( MYBPC3 )	肥大型心肌病更多	临床申请批准