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SON-1010 is a targeted immune activation cancer therapy designed to turn ‘cold’ tumors ‘hot’ Topline safety data of SB101 Phase 1 study expected by Q4 2024 Sept. 18, 2024 -- Sonnet BioTherapeutics Holdings, Inc. (the “Company” or “Sonnet”) (NASDAQ: SONN), a clinical-stage company developing targeted immunotherapeutic drugs, today announced the completion of enrollment and initiation of dosing in its Phase 1 SB101 clinical trial of SON-1010 (IL12-FHAB) in adult patients with advanced solid tumors. The Company expects to report topline data from this study in Q4 2024. Pankaj Mohan, Founder and Chief Executive Officer of Sonnet commented, “This milestone is an important step forward in our development program for SON-1010 as a monotherapy. We are encouraged by the data seen to date demonstrating safety and tolerability being well within expected levels. We are hopeful that we will continue to see extended PK/PD, tumor targeting and clinical activity during treatment. We remain committed to bringing this trial to completion and we expect to report topline safety data in Q4 2024.” SB101 is the Company’s open-label, adaptive-design dose-escalation study to assess the safety, tolerability, and PK/PD of SON-1010 administered to patients with advanced solid tumors. The study enrolled 24 subjects. Primary outcome measures for the study are to evaluate the safety and tolerability of SON-1010 and establish the maximum tolerated dose (MTD) of SON-1010. SON-1010 is the Company’s proprietary version of recombinant human interleukin-12 (rhIL-12), configured using Sonnet’s Fully Human Albumin Binding (FHAB®) platform, which extends the half-life and activity of the IL-12 component due to binding native albumin in the serum and targets the tumor microenvironment (TME) by strongly binding gp60 and Secreted Protein Acidic and Rich in Cysteine (SPARC). As previously announced, the safety of SON-1010 was reviewed by the Safety Review Committee at each step during dose escalation. The trial uses a ‘desensitizing’ first dose to take advantage of the known tachyphylaxis with rhIL-12, which minimizes toxicity and allows higher maintenance doses. No dose-limiting toxicities have occurred to date. The safety and toxicity profile that has developed is typical for a Phase 1 oncology trial, with the majority of adverse events (AEs) being reported as mild. All have been transient, with no evidence of cytokine release syndrome. As previously announced, one patient with progressive endometrial sarcoma receiving SON-1010 monotherapy in SB101 had stable disease (SD) for almost 2 years before progressing - her ascites had resolved and tumors had shrunk at one point but she never reached a partial response (PR) by Response Evaluation Criteria in Solid Tumors (RECIST) rules. Cytokine analysis following each dose in that study revealed controlled and prolonged induction of interferon gamma (IFNγ) that peaked at 24 to 48 hours and returned to baseline within 2 to 4 weeks. A small increase in IL-10 was observed with each dose as expected in response to IFNγ. There was either a minimal or no signal for IL-1β, IL-6, IL-8, and TNFα, and there was no indication of any potential for cytokine release syndrome (CRS) at these doses. For more information about the SB101 Phase 1 trial in adult patients with advanced solid tumors visit www.clinicaltrials.com and reference identifier NCT05352750. SON-1010 is a candidate immunotherapeutic recombinant drug that links unmodified single-chain human IL-12 with the albumin-binding domain of the single-chain antibody fragment A10m3. This was selected to bind albumin both at normal pH, as well as at the acidic pH typically found in the TME. The FHAB technology targets tumor and lymphatic tissue, providing a mechanism for dose sparing and an opportunity to improve the safety and efficacy profile of not only IL-12, but a variety of potent immunomodulators that can be linked using the platform. Interleukin-12 can orchestrate a robust immune response to many cancers and pathogens. Given the types of proteins induced in the TME, such as the Secreted Protein and Rich in Cysteine (SPARC) and glycoprotein 60 (GP60), several types of cancer such as non-small cell lung cancer, melanoma, head and neck cancer, sarcoma, and some gynecological cancers are particularly relevant for this approach. SON-1010 is designed to deliver IL-12 to local tumor tissue, turning ‘cold' tumors ‘hot' by stimulating IFNγ, which activates innate and adaptive immune cell responses and increases the production of Programed Death Ligand 1 (PD-L1) on tumor cells. This first-in-human study is primarily designed to evaluate the safety of multiple ascending doses of SON-1010 in cancer patients and is being conducted at several sites across the United States. While the optimal dose is unknown at this stage, the potential to target tumors, the extended PK mechanism, and our preclinical data suggest the therapeutic dose may be lower compared to native human IL-12. The study, utilizing a standard 3+3 oncology design in at least five cohorts, should establish the MTD using subcutaneous injections of SON-1010 every 3 to 4 weeks. The primary endpoint explores the safety and tolerability of SON-1010, with key secondary endpoints intended to measure pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and anti-tumor activity. This study will form the basis for potential combinations with other types of immunotherapies and the future development of bispecific candidates using the FHAB platform. Sonnet is an oncology-focused biotechnology company with a proprietary platform for developing targeted biologic drugs with single or bifunctional action. Known as FHAB (Fully Human Albumin Binding), the technology utilizes a fully human single chain antibody fragment (scFv) that binds to and "hitch-hikes" on human serum albumin (HSA) for transport to target tissues. Sonnet's FHAB was designed to specifically target tumor and lymphatic tissue, with an improved therapeutic window for optimizing the safety and efficacy of immune modulating biologic drugs. FHAB platform is the foundation of a modular, plug-and-play construct for potentiating a range of large molecule therapeutic classes, including cytokines, peptides, antibodies and vaccines. Sonnet’s lead program, SON-1010, or IL-12-FHAB, is in development for the treatment of solid tumors and ovarian cancer. SON-1010 is being evaluated in an ongoing Phase 1/2a study through a Master Clinical Trial and Supply Agreement, along with ancillary Quality and Safety Agreements, with Roche in combination with atezolizumab (Tecentriq®) for the treatment of Platinum-Resistant Ovarian Cancer (PROC). The Company is also evaluating its second program, SON-1210, an IL12-FHAB-IL15 for solid tumors, in collaboration with the Sarcoma Oncology Center to commence an investigator-initiated and funded Phase 1/2a study for the treatment of pancreatic cancer. The Company’s SON-080 program is a low dose of rhIL-6 in development for Chemotherapy-Induced Peripheral Neuropathy (CIPN) and Diabetic Peripheral Neuropathy (DPN). SON-080 demonstrated encouraging results in a Phase 1b/2a clinical trial, being well tolerated with no evidence of a pro-inflammatory cytokine response. Sonnet is currently seeking partnership opportunities to support a Phase 2 trial. 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Sales recorded KRW 33 billion in Q3 2023, an 11 percent increase from the same period in 2022, due to the sustained growth of major products. 'HL161ANS', HanAll's second anti-FcRn antibody, demonstrated best-in-class potential through the initial outcome of Phase 1 study. 'HL192', a Nurr1 activator co-developed for Parkinson's Disease (PD) by NurrOn, Daewoong, and HanAll, started the first-in-human study. HanAll continues to invest in R&D supported by the strong financial performance. ROCKVILLE, Md. and SEOUL, South Korea, Oct. 26, 2023 /PRNewswire/ -- HanAll Biopharma Co., Ltd. (KRX: 009420.KS), a global biopharmaceutical company committed to discovering and developing innovative medicines for patients, reported financial results for the third quarter and provided business updates. HanAll ended the quarter with a revenue of 33 billion Korean won (KRW), an 11 percent increase year-on-year, mainly driven by two-digit growth from key pharmaceutical products. The net profit recorded was 300 million KRW, with an operation income of 100 million KRW. "The third quarter marked a significant milestone. Our second anti-FcRn asset, HL161ANS (IMVT-1402), demonstrated a favorable safety and efficacy profile from the initial phase 1 Single Ascending Dose (SAD) and 300 mg subcutaneous MAD study, indicating it may be a potentially best-in-class anti-FcRn antibody for the treatment of IgG-mediated autoimmune diseases. We have also successfully initiated a Phase 1 clinical study for HL192 (ATH-399A) in collaboration with our partners to evaluate its potential as a treatment for Parkinson's disease," said Sean Jeong, M.D., MBA, CEO of HanAll Biopharma. "In the fourth quarter, we anticipate the Phase 2 initial results for batoclimab in Grave's disease as well as additional MAD study results for HL161ANS 600 mg. We also plan to finalize the next Phase 3 study design for tanfanercept in dry eye disease before the end of 2023. We stay dedicated to our mission to humbly serve our patients by continuing to evolve ourselves into a global innovative biopharmaceutical company," he added. THIRD QUARTER 2023 BUSINESS UPDATE Pipeline Development Highlights A comprehensive update of HanAll's pipeline development below includes an overview of research along with lists of compounds, targeted indications, and developmental phase. AUTOIMMUNE DISEASES PROGRAMS Batoclimab (HL161BKN) A novel, fully human, subcutaneously administered antibody targeting FcRn with the potential to address multiple IgG-mediated autoimmune diseases. Batoclimab is designed to selectively bind to FcRn, which plays a role in recycling IgG, thereby reducing levels of harmful IgG antibodies. Harbour BioMed, a licensed partner in China, announced the official acceptance of the Biologics License Application (BLA) of batoclimab for the treatment of generalized myasthenia gravis (gMG) in June 2023. This application was based on a positive topline result from the Phase 3 clinical trial in March 2023. Immunovant, another licensed partner in United States and Europe, is actively engaged in the development of a FcRn inhibitor in four autoimmune indications: Grave's disease (GD), Chronic inflammatory demyelinating polyneuropathy (CIDP), gMG and Thyroid eye disease (TED). Anticipated milestones include the initial Phase 2 results for GD in the fourth quarter of 2023 and the initial data from Phase 2b clinical trials for CIDP in the first half of 2024. The top-line results from the gMG Phase 3 study are expected in the second half of 2024, with top-line data from the Phase 3 clinical study at TED expected in the first half of 2025. HanAll and Immunovant initiated a Phase 3 clinical study of batoclimab in gMG in Japan while preparing to initiate a Phase 3 study in TED. HL161ANS Another novel, fully human, subcutaneous antibody molecule that inhibits FcRn-mediated recycling of IgG is designed to deliver maximum lgG reductions while minimizing interference with albumin recycling. Immunovant announced favorable initial HL161ANS (Immunovant project designation: IMVT-1402) Phase 1 SAD and 300 mg MAD results in September 2023. In the MAD portion of the study, HL161ANS achieved a 63% lgG reduction from the baseline after four weekly doses of 300 mg subcutaneous administration. No decrease in serum albumin below baseline and no increase in LDL-cholesterol level above baseline were observed. Overall, HL161ANS demonstrated a consistent reduction in lgG level with potency similar to or greater than that of batoclimab, without significant reduction from baseline of serum albumin levels and without significant increase in LDL-cholesterol levels observed at any timepoint measured (all p's > 0.05). Additional data from the MAD 600 mg cohort is expected in the fourth quarter of 2023. OPHTHALMIC DISEASE PROGRAM Tanfanercept (HL036) A novel topical protein therapy for ophthalmic diseases, including dry eye disease (DED), which inhibits TNF alpha, a key mediator of ocular inflammation HanAll Biopharma and Daewoong Pharmaceutical conducted an in-depth medical advisory board meeting to discuss the completed Phase 3 VELOS-3 study data and the planned Phase 3 VELOS-4 study design of tanfanercept ophthalmic solution for the treatment of DED. HanAll and Daewoong intend to discuss the VELOS-4 study design and development plan with the FDA within the second half of 2023, with plans to begin the next study in the year of 2024. The completed Phase 3 VELOS-3 study demonstrated a highly statistically significant improvement in the secondary efficacy endpoint of the unanesthesized Schirmer test, evaluating the change in tear volume from baseline in subjects treated with tanfanercept compared to vehicle assessed at week 8 (p=0.002). Additionally, the proportion of subjects whose Schirmer test improved from baseline by at least 10 mm, as assessed at week 8, was statistically significant (p=0.011) in the tanfanercept arm (13%) relative to the vehicle arm (4%). It is notable that per the FDA's 2020 Draft Guidance on Dry Eye Drug Development, measurement of a statistically significant difference between the percentage of patients achieving at least a 10 mm increase in Schirmer test is an acceptable primary efficacy endpoint option. Another DED approval pathway option which the FDA has published would include demonstrating both an objective prespecified sign of dry eye but additionally requires at least one subjective prespecified symptom of dry eye. This second pathway often involves a greater degree of complexity, requiring additional studies to be conducted. NEUROLOGY PROGRAM HL192 (ATH-399A) A pipeline candidate originated from NurrOn Pharmaceuticals that targets Nurr1, a master regulator in dopaminergic neuron development and maintenance, is being developed to treat neurodegenerative diseases, including Parkinson's disease (PD). HanAll Biopharma, Daewoong Pharmaceutical, and NurrOn Pharmaceuticals initiated a Phase 1 clinical trial of HL192, which is being developed for the treatment of PD. This Phase 1 Study evaluates the safety, tolerability, and pharmacokinetics of both single and multiple doses of orally administered HL192 in healthy subjects. The initial results from the Phase 1 clinical trial of HL192 are expected in the second half of 2024. ONCOLOGY PROGRAMS HL187/ HL186 HL187 is a monoclonal antibody that targets TIGIT (T cell immunoreceptors with Ig and ITIM domains {Immunoreceptor tyrosine-based inhibitory motif domains}). HL186 is a monoclonal antibody that targets TIM-3 (T cell Ig and mucin domain-3). These antibodies are being developed in collaboration with Daewoong Pharmaceutical as potential oncology treatments. HanAll is currently progressing with the pre-clinical study of HL187 (anti-TIGIT), while assessing the potential of HL186 (anti-TIM-3) under the strategic portfolio review. FINANCIAL HIGHLIGHTS (CONSOLIDATED) Key Highlights Sales recorded 33 billion KRW for the three-month period ending on September 30, 2023, an 11 percent increase from the three months ended September 30, 2022. The increase was primarily due to strong pharmaceutical sales, including 'Normix', 'Eligard', and 'BioTop'. Research and development expenses were 4.6 billion KRW for the three-month period ending on September 30, 2023, up by 6 percent compared to the same period in 2022. Net income was 300 million KRW for the three-month period ending on September 30, 2023, compared to 700 million KRW for the three months ended September 30, 2022. About HanAll Biopharma HanAll Biopharma (KRX: 009420.KS) is a global biopharmaceutical company with presence in Korea, the USA, Japan, and Indonesia with a mission of making meaningful contributions to patients' lives by introducing innovative, impactful medicines to address severe unmet medical needs. HanAll has been operating a portfolio of pharmaceutical products for 50 years. HanAll has also expanded its focus in recent years to immunology, oncology, neurology, and ophthalmology to discover and develop innovative medicines for patients with diseases for which there are no effective treatments. Its lead pipeline asset, HL161 (INN: batoclimab), an anti-FcRn antibody, is being developed in Phase 3 and Phase 2 trials across the world for the treatment of autoimmune diseases including generalized myasthenia gravis (gMG), thyroid eye disease (TED), chronic inflammatory demyelinating polyneuropathy (CIDP), and Graves' disease (GD). Another main asset, HL036 (INN: tanfanercept), a TNF-alpha inhibitor protein, is under development in Phase 3 clinical studies in the US for the treatment of dry eye disease. For further information, visit our website and connect with us on LinkedIn. For any media inquiries, please contact HanAll PR/IR ([email protected], [email protected]). Disclaimer Statement The contents of this announcement include statements that are, or may be deemed to be, "forward-looking statements." These forward-looking statements can be identified by the use of forward-looking terminology, including the terms "believes," "estimates," "anticipates," "expects," "intends," "may," "will," or "should," and include statements HANALL (the company, we) makes concerning its 2023 business and financial outlook and related plans; the therapeutic potential of its product candidates; the intended results of its strategy and the company, and its collaboration partners', advancement of, and anticipated clinical development, data readouts and regulatory milestones and plans, including the timing of planned clinical trials and expected data readouts; the design of future clinical trials and the timing and outcome of regulatory filings and regulatory approvals. By their nature, forward-looking statements involve risks and uncertainties, and readers are cautioned that any such forward-looking statements are not guarantees of future performance. The company's actual results may differ materially from those predicted by the forward-looking statements. These may include various significant factors, such as our expectations regarding the inherent uncertainties associated with competitive developments, preclinical and clinical trial and product development activities, and regulatory approval requirements. In addition, performance may be affected by our reliance on collaborations with third parties, estimating the commercial potential of our product candidates, our ability to obtain and maintain protection of intellectual property of technologies and drugs, our limited operating history, and our ability to obtain additional funding for operations and to complete the development and commercialization of product candidates. A further list and description of these risks, uncertainties, and other risks can be found in Korea Stock Exchange (KRX) filings and reports, including in our most recent annual report as well as subsequent filings and reports filed by the company with the KRX. Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements. These forward-looking statements speak only as of the date of publication of this document. We undertake no obligation to publicly update or revise the information in this press release, including any forward-looking statements, except as may be required by Korean law and regulations. SOURCE HanAll Biopharma

Financial results for the first quarter ended with revenue of KRW 28.8 billion, up by 20 percent compared to the same period in 2022 HanAll made a strong start to 2023 with positive Phase 3 study results of anti-FcRn asset batoclimab for the treatment of generalized myasthenia gravis in China, setting a monumental milestone for anti-FcRn developers in the global market HanAll is on track with its ongoing pivotal Phase 3 clinical study of tanfanercept (VELOS-3) in dry eye disease in the first half of 2023 ROCKVILLE, Md. and SEOUL, South Korea, April 28, 2023 /PRNewswire/ -- HanAll Biopharma Co., Ltd. (KRX: 009420. KS), a global biopharmaceutical company committed to discovering and developing innovative medicines for patients, reported financial results for the first quarter and provided business updates. HanAll's financial data demonstrated a strong momentum in the start of 2023, with revenues of KRW 28.8 billion, representing a 20 percent sales growth mainly driven by pharmaceutical sales from the first quarter of 2022. The company reported a net loss of 1.3 billion won due to continued investment in R&D. Following the previous statement from the 2022 full-year financial report, HanAll expects to secure top-line data from the tanfanercept Phase 3 clinical study in dry eye disease in the first half of 2023 and plans to initiate a Phase 3 clinical study of batoclimab in generalized myasthenia gravis (gMG) in Japan this year. "The recent positive top-line result from gMG Phase 3 study by Harbour BioMed suggests the potential of batoclimab as the first anti-FcRn treatment to be commercialized in China, reinforcing our confidence to develop batoclimab in an array of autoimmune diseases. With a strong focus on collaboration and innovation, we will continue to push forward with our R&D programs to deliver groundbreaking medicines that will make a difference in the patients' lives," said Sean Jeong, M.D., MBA, CEO of HanAll Biopharma. First Quarter 2023 BUSINESS UPDATE Pipeline Development Highlights A comprehensive update of HanAll's pipeline development below includes an overview of research along with lists of compounds and targeted indications, along with developmental phase. AUTOIMMUNE DISEASES PROGRAMS Batoclimab (HL161BKN) A novel, fully human, subcutaneously administered antibody targeting FcRn, with the potential to address multiple IgG-mediated autoimmune diseases. Batoclimab is designed to selectively bind to and inhibit FcRn, which plays a role in recycling IgG, thus leading to a reduction in IgG antibodies. Harbour BioMed, a licensed partner of HanAll in China, announced the first positive Phase 3 top-line results for batoclimab in generalized myasthenia gravis (gMG) subjects in March 2023. Data from the trial met the primary endpoint as well as key secondary endpoints. Batoclimab treatment was also found to be overall safe and well-tolerated, without any new significant safety signals identified. Harbour BioMed plans to submit a Biologics License Application (BLA) to the National Medical Products Administration (NMPA) for batoclimab together with its sub-licensee CSPC NBP Pharmaceuticals Co., Ltd. (NBP Pharma), a wholly-owned subsidiary of CSPC Pharmaceutical Group Limited (CSPC Pharmaceutical), based on the study results. Batoclimab is also being developed for study in China in an array of other autoimmune disorders including thyroid eye disease (TED). HanAll is progressing towards initiation of a Phase 3 clinical study of batoclimab in gMG in Japan this year. Additionally, HanAll is exploring options for developing batoclimab in TED and chronic inflammatory demyelinating polyneuropathy (CIDP) in Japan. Another licensed partner, Immunovant in the U.S. and Europe, is conducting global Phase 3 trials with batoclimab in gMG and TED. Additionally, the initial data readout for a Phase 2 trial in Grave's disease (GD) is anticipated in the second half of 2023 and an initial Phase 2b results in CIDP is expected in the first half of 2024. HL161ANS Another novel, fully human, subcutaneous antibody molecule that inhibits FcRn-mediated recycling of IgG, designed to deliver maximum lgG reductions while minimizing interference with albumin recycling. Immunovant anticipates initial results from a Phase 1 trial for HL161ANS, a new FcRn inhibitor (Immunovant project designation: IMVT-1402), in the second half of 2023. Immunovant also plans to evaluate HL161ANS in multiple autoimmune diseases , based on strategic portfolio considerations. OPHTHALMIC DISEASE PROGRAMS Tanfanercept (HL036) A novel topical protein therapy for ophthalmic diseases, including dry eye disease (DED), which inhibits TNF alpha, a key mediator of ocular inflammation HanAll Biopharma and Daewoong Pharmaceutical are progressing with the second Phase 3 (VELOS-3) study in the U.S. in subjects with moderate to severe DED to examine the safety and efficacy of tanfanercept. Study enrollment is complete and the top-line results from the VELOS-3 study are expected in the first half of 2023 . Harbour BioMed, a licensed partner of HanAll in China, closed its Phase 3 China study in DED, based on the Independent Data Monitoring Committee's (IDMC) evaluation of the efficacy data from the second interim analysis. The HanAll U.S. study (VELOS-3) differs from the Harbour Chinese study in a number of ways including key inclusion criteria, primary endpoints, as well as subject demographics. The future development plans for tanfanercept in China are under discussion. ONCOLOGY PROGRAMS HL187/ HL186 Monoclonal antibodies that respectively target T cell immunoreceptors with Ig and ITIM {Immunoreceptor tyrosine-based inhibitory motif} domains (TIGIT) and T cell immunoglobulin and mucin domain-3 (TIM-3) are being developed in collaboration with Daewoong Pharmaceutical. as potential oncology treatments HanAll is continuing with the pre-clinical development of HL187 asset and plans to evaluate the further development of HL186 based on the strategic portfolio review. FINANCIAL HIGHLIGHTS (CONSOLIDATED) Key Highlights Sales recorded 28.8 billion won in the first quarter of 2023, a 20 percent increase compared to the first quarter of 2022. Pharmaceutical sales remained strong with major products including Normix, Eligard, along with the newly launched products such as Abcito and Glucofree. Research and development expenses for the first quarter ended March 31, 2023 were 5.9 billion won, up 88 percent from 3.1 billion won for the three months ended March 31, 2022. The increase was primarily due to continued progress in VELOS-3 study, along with the investment to the ongoing oncology projects. Net loss for the three months ended March 31, 2023 recorded 1.3 billion won from the 0.1 billion won for the same period in 2022. About HanAll Biopharma Co., Ltd. HanAll Biopharma (KRX: 009420.KS) is a global biopharmaceutical company founded in 1973, with a mission of making meaningful contributions to patients' lives by introducing innovative, impactful therapies to address severe unmet medical needs. HanAll has been operating a portfolio of pharmaceutical products in areas ranging from endocrine, circulatory, and urologic diseases for more than 50 years. HanAll has also expanded its focus to ophthalmology, immunology, oncology and neurology to discover and develop innovative medicines for patients with diseases for which there are no effective treatments. Its lead pipeline asset, HL161 (INN: batoclimab), an anti-FcRn antibody, is being developed in Phase 3 and Phase 2 trials across the world for the treatment of autoimmune diseases including myasthenia gravis (MG), thyroid eye disease (TED), chronic inflammatory demyelinating polyneuropathy (CIDP), and Graves' disease (GD). Another main asset, HL036 (INN: tanfanercept), a TNF-alpha inhibitor protein, is being evaluated in Phase 3 clinical studies in the US and China for the treatment of dry eye disease. For further information connect with us on linkedin. For any media inquiries, please contact HanAll PR/IR ([email protected], [email protected]). Disclaimer statement The contents of this announcement include statements that are, or may be deemed to be, "forward-looking statements." These forward-looking statements can be identified by the use of forward-looking terminology, including the terms "believes," "estimates," "anticipates," "expects," "intends," "may," "will," or "should" and include statements HanAll (the company, we) makes concerning its 2023 business and financial outlook and related plans, the therapeutic potential of its product candidates, the intended results of its strategy and the company, and its collaboration partners', advancement of, and anticipated clinical development, data readouts and regulatory milestones and plans, including the timing of planned clinical trials and expected data readouts, the design of future clinical trials and the timing and outcome of regulatory filings and regulatory approvals. By their nature, forward-looking statements involve risks and uncertainties, and readers are cautioned that any such forward-looking statements are not guarantees of future performance. The company's actual results may differ materially from those predicted by the forward-looking statements. These may include various significant factors such as our expectations regarding the inherent uncertainties associated with competitive developments, preclinical and clinical trial and product development activities and regulatory approval requirements. In addition, performance may be affected by our reliance on collaborations with third parties, estimating the commercial potential of our product candidates, our ability to obtain and maintain protection of intellectual property of technologies and drugs, our limited operating history, and our ability to obtain additional funding for operations and to complete the development and commercialization of product candidates. A further list and description of these risks, uncertainties and other risks can be found in Korea Stock Exchange (KRX) filings and reports, including in our most recent annual report as well as subsequent filings and reports filed by the company with the KRX. Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements. These forward-looking statements speak only as of the date of publication of this document. We undertake no obligation to publicly update or revise the information in this press release, including any forward-looking statements, except as may be required by Korean law and regulations. SOURCE HanAll Biopharma