别名 Amyotrophies, Diabetic、Amyotrophy, Diabetic、Asymmetric Diabetic Proximal Motor Neuropathy + [143] |
简介 Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) |
靶点 |
作用机制 CACNA2D1阻滞剂 |
在研机构 |
原研机构 |
非在研适应症- |
最高研发阶段批准上市 |
首次获批国家/地区 中国 |
首次获批日期2024-05-15 |
作用机制 50S subunit抑制剂 [+1] |
原研机构 |
在研适应症 |
最高研发阶段批准上市 |
首次获批国家/地区 中国 |
首次获批日期2021-06-01 |
靶点- |
作用机制 Macrophages调节剂 |
在研机构 |
原研机构 |
在研适应症 |
非在研适应症- |
最高研发阶段批准上市 |
首次获批国家/地区 中国台湾 |
首次获批日期2021-03-26 |
开始日期2025-09-01 |
申办/合作机构 |
开始日期2025-03-21 |
申办/合作机构- |
开始日期2024-12-30 |
申办/合作机构 |