Dexpanthenol

TUESDAY, April 4, 2023 (American Heart Association News) -- If you think of carrots as stodgy old tubers, something more fit for rabbits than healthy humans, you're in for a bunch of surprises. Carrots can be a significant source of crucial nutrients, said Sherry Tanumihardjo, professor of nutritional sciences at the University of Wisconsin-Madison. These days, they're popping up in a whole palette of colors. They're also convenient and versatile. "You can just take them out of the ground, wash them and eat them, just like that, or you can peel them and cut them up," she said. "You can slice them and dice them into all kinds of foods." Carrots have been around a long time, probably originating in central Asia, possibly Afghanistan. Researchers say that by the Middle Ages, purple and white varieties were domesticated as far west as England, but the orange carrot didn't become common until the 15th century in Europe. Tanumihardjo has quite a carrot history herself, having studied them since the start of this century and collaborated on work that's helped make a rainbow of varieties widely available. Although carrots carry a range of nutrients, including B vitamins, vitamin K and potassium, much of her carrot enthusiasm comes from her work in vitamin A, which supports the immune system, heart, lungs and perhaps most famously, eye health. "Vitamin A is essential for vision, especially at night," she said, meaning that what your grandmother told you about eating carrots to help you see in the dark has some truth to it. (The idea that carrots can improve eyesight is rooted in British World War II propaganda, but vitamin A deficiency causes hundreds of thousands of cases of night blindness worldwide each year.) Vitamin A comes in two forms. Preformed vitamin A can be found in animal products, such as dairy products and organ meats. Taken in excess, as in supplements, preformed vitamin A can become toxic. The other form, provitamin A, is derived from plant-based chemicals called, conveniently enough, carotenoids. Not all carotenoids can be converted to vitamin A, but orange carrots are full of some that do, such as alpha and beta carotene. "It's a safer way to get vitamin A because your body regulates it," Tanumihardjo said. That is, your body can make more or less, depending on what it needs at the moment. As calculated by the U.S. Department of Agriculture, one regular raw carrot, weighing about 2 ounces (or 60 grams), comes with about 25 calories and would provide nearly 72% of the vitamin A an adult woman's needs, and about 56% of an adult man's daily needs. In the carrot world, colors are trending, and as colors vary, so do nutrients. Purple carrots get their hue from anthocyanins, which have been linked to healthy gut biomes, improved cognition and better heart health. Yellow carrots provide lutein, which helps vision and brain health. And red carrots contain lycopene, which also is found in red tomatoes and watermelon, and which has been linked to lower stroke risk. More varieties may be on the way, Tanumihardjo said. "Right now, we are working on a purple carrot with a red center." Carrots also have heart-healthy fiber. According to the USDA, one regular raw carrot provides 1.7 grams. Federal dietary guidelines say an adult needs 22 to 34 grams a day, depending on age and sex. Tanumihardjo said the nutrients in carrots are available fresh or frozen, raw or cooked. Cooking, she said, breaks down the cell walls releasing compounds that help sweeten carrots a bit. Some studies have shown that cooking actually increases levels of available carotenoids. She did have one carrot caveat, however: If you eat raw carrots without a fat source, you won't see benefits from those carotenoids. "It will just pass right on through the body," she said. "If you eat carrots in a salad and you have salad dressing, then you will absorb more. If you eat carrots in a stew, and you don't overcook them too much, and there's fat in the stew, you will absorb even more." Eating them with a little bit of cheese also would work, she said. The same goes for carrot juice. Juicing breaks cell membranes and helps make carotenoids more accessible, "but you do have to make sure you have a little bit of fat within the same time you're drinking the juice in order to absorb the most nutrients." Although peeling them will remove a little fiber, when it comes to serving carrots, there really isn't a bad way, she said. (Unless, perhaps, you are a rabbit. According to Britain's Royal Society for the Prevention of Cruelty to Animals, wild rabbits don't eat carrots, and they should only be an occasional treat for pets. The whole connection between bunnies and carrots can be traced to the debut of Bugs Bunny in 1940. His carrot crunching was intended as a parody of Clark Gable in the 1934 comedy, "It Happened One Night.") "I do like carrots," Tanumihardjo said. Sometimes she snacks on baby carrots, a peeled and cut version with similar nutritional values. Mostly, she said, she buys longer ones and puts them in soup. "I make a lot of soup." American Heart Association News covers heart and brain health. Not all views expressed in this story reflect the official position of the American Heart Association. Copyright is owned or held by the American Heart Association, Inc., and all rights are reserved. By Michael Merschel, American Heart Association News Posted April 2023

集团销售额增长 8.7% （经汇率与资产组合调整），达到 507.39 亿欧元 不计特殊项目的息税折旧摊销前利润增长 20.9% ，达到 135.13 亿欧元，主要得益于作物科学事业部强劲的业绩表现 处方药事业部销售额和收益实现增长 健康消费品事业部保持强劲增长 每股核心收益增长 22.0% ，达到 7.94 欧元 净收益达到 41.50 亿欧元 自由现金流增长至 31.11 亿欧元 每股拟派股息为 2.40 欧元，增长 20% 新产品实现大幅增长 研发产品线进展可喜 在实现长期可持续发展目标方面取得重大进展 2023 年展望：销售额（经汇率与资产组合调整）实现大幅增长 勒沃库森 2023年2月28日 /美通社/ -- 拜耳集团在 2022 财年实现强劲增长，销售额和收益双双大幅增长。周二，管理委员会主席沃纳 • 保曼（ Werner Baumann ）在公司财报新闻发布会上表示， “ 尽管面临诸多挑战，拜耳在 2022 财年仍取得了强劲的业绩表现。即使在这样的困难时期，我们也能够持续交付产品并实现我们八月上调后的财务目标。 ” 他还表示，拜耳始终活跃在正确的行业领域。 “ 健康和营养是人们的基本需求。拜耳 共享健康，消除饥饿 的愿景现在和将来均至关重要，特别是在我们当下所处的时代。 ” 拜耳集团 2022 财年的销售额增长 8.7% （经汇率与资产组合调整），达到 507.39 亿欧元。不计特殊项目的息税折旧摊销前利润增长 20.9% ，达到 135.13 亿欧元，其中包括汇率变动带来的 4.29 亿欧元的积极影响（ 2021 年：汇率变动带来 5.07 亿欧元的不利影响）。不计特殊项目的息税折旧摊销前利润率为 26.6% （ 2021 年： 25.4% ）。息税前利润增长至 70.12 亿欧元，较上一财年同比增长超过一倍。净收益达到 41.50 亿欧元（ 2021 年： 10.00 亿欧元），每股核心收益增长 22.0% ，达到 7.94 欧元。自由现金流达到 31.11 亿欧元，较上一财年同比增长超过一倍。 “ 拜耳上一财年业绩表现强劲。因此，我们与监事会一道，向年度股东大会提议派发 2.40 欧元股息，较上一财年实现 20% 的增长， ” 首席财务官 Wolfgang Nickl 表示。享有股息的股份达到 9.8242 亿股，因此，拜耳将在 2022 财年向股东分红总计 23.58 亿欧元（ 2021 财年： 19.65 亿欧元）。 作物科学事业部销售额再创新高，利润率行业领先 农业业务（作物科学事业部）销售额增长了 15.6% （经汇率与资产组合调整），达到创纪录的 251.69 亿欧元，在所有地区均实现业务增长。除草剂业务增长最为强劲（经汇率与资产组合调整后达到 43.9% ），特别是由于草甘膦产品供应紧张，价格上涨，该业务在拉丁美洲和北美洲以及欧洲 / 中东 / 非洲的销售额上升。随着该部门市场份额的增加，玉米种子与性状业务的销售额增长了 8.8% （经汇率与资产组合调整）。杀菌剂的销售额增长了 5.2% （经汇率与资产组合调整），拉丁美洲和欧洲 / 中东 / 非洲地区的价格上涨显著抵消了北美地区销量的下降。大豆种子与性状业务的销售额与上一年持平。 作物科学事业部不计特殊项目的息税折旧摊销前利润增长了 46.2% ，达到 68.67 亿欧元，主要得益于销售额的大幅增长。盈利还受益于正在进行的提升效率项目和 2.84 亿欧元的积极汇率影响（ 2021 年： 3.87 亿欧元的汇率损失影响）。不计特殊项目的息税折旧摊销前利润率增长了 4.1% ，达到 27.3% ，行业领先。 处方药事业部业务受益于新产品和艾力雅 ® 的增长 处方药（处方药事业部）销售额增长了 1.1% （经汇率与资产组合调整），达到 192.52 亿欧元。超过 5 亿欧元的销售额来自该部门的新产品：抗癌药诺倍戈 ® 和用于治疗与 2 型糖尿病相关慢性肾病的可申达 ® 。其中，诺倍戈 ® 的销售额同比几乎翻了一番。眼科药物艾力雅 ® （经汇率与资产组合调整后增长 9.2% ）和影像诊断业务也实现了强劲增长，包括加乐显 ® （经汇率与资产组合调整后增长 9.0% ）和优维显 ® （经汇率与资产组合调整后增长 17.5% ）。 受益于销售额的增长，以及在较小程度上受益于出售非核心业务的收入，处方药事业部不计特殊项目的息税折旧摊销前利润增长了 1.6% ，达到 58.73 亿欧元。 健康消费品事业部在所有地区和品类均实现销售额增长 自我保健产品（健康消费品事业部）销售额增长 8.4% （经汇率与资产组合调整），达 60.80 亿欧元，在上一财年强劲表现的基础上，所有地区和品类的销售额继续实现增长。过敏与感冒业务的增长最为强劲，由于感冒发病率的持续上升和 Astepro™ 抗组胺鼻喷雾剂在美国的上市，过敏与感冒品类的销售额实现 21.5% 的显著增长。皮肤品类也实现了两位数的增长（经汇率与资产组合调整后为 10.5% ），对 Bepanthen™ 的需求增加是该品类实现增长的因素之一。在经历了上一财年的强劲表现后，营养品业务的销售额依旧保持增长（经汇率与资产组合调整后为 1.0% ）。 由于销售额的大幅增长以及一系列提升生产力的项目和积极的价格管理所作出的强势贡献，健康消费品事业部不计特别项目的息税折旧摊销前利润增长了 14.9% ，达到 13.67 亿欧元。即便身处通货膨胀导致成本大幅上涨的商业环境，该事业部实现了业务增长，同时还为创新产品的上市，特别是 Astepro™ ，进行了大量投资。汇率变动带来了 8500 万欧元的积极影响（ 2021 年： 3900 万欧元的汇率损失影响）。不计特殊项目的息税折旧摊销前利润率为 22.5% ，与上一财年持平。 展望：销售额进一步增长 保曼表示： “ 在连续两年的高个位数增长率之后，我们预计公司业务增长将保持在较高水平，并在 2023 年经汇率与资产组合调整后增长 2%-3% 。 ” 拜耳预计农业除草剂以及部分成熟药品的价格会降低。预计投资组合的其他部分和新产品的销售额增长将产生积极影响。 经汇率调整（即基于 2022 年的月平均汇率）后，拜耳预计 2023 年的销售额将达到 510 亿至 520 亿欧元。公司预计不计特殊项目的息税折旧摊销前利润经汇率调整后为 125 亿至 130 亿欧元。预测每股核心收益为 7.20 至 7.40 欧元（经汇率调整），自由现金流约为 30 亿欧元（经汇率调整）。 对于事业部（经汇率与资产组合调整），拜耳预计作物科学事业部销售额将增长约 3% ，处方药事业部增长约 1% ，健康消费品事业部增长约 5% 。拜耳还预计，经汇率调整后的作物科学事业部、处方药事业部、健康消费品事业部不计特殊项目的息税折旧摊销前利润率将分别为 25%-26% 、 29% 、 23% 。 拜耳还根据截至 2022 年 12 月 31 日的收盘汇率做出预测，与上述经汇率调整后的预测差异如下：集团销售额预计为 500 亿至 510 亿欧元，处方药事业部不计特殊项目的息税折旧摊销前利润率预计将达到 30% 左右。 在创新和可持续发展方面取得重大进展 拜耳在上市和开发创新方面也取得了重大进展。这一点在处方药事业部尤为突出，例如，新产品诺倍戈 ® 和可申达 ® ，以及处于后期开发阶段的项目，如用于预防房颤患者卒中的 atsundexian 和用于治疗女性更年期疾病的 elinzanetant 。公司目前认为，上述重要增长产品的年峰值销售将超过 120 亿欧元。作物科学事业部推进了旨在更有效地保护收成并减少对环境影响的新产品上市。在生物学领域，该事业部将其研究方法转变为开放式创新模式，例如，该事业部与位于波士顿的生物技术公司 Ginkgo Bioworks 和西班牙生物公司 Kimitec 进行了战略合作。最后，健康消费品事业部优化了其产品组合，增加了 Astepro™ ，这是美国市场上首个可在柜台购买的不含类固醇的抗组胺喷雾剂。该药物开始发挥作用的速度更快，可为过敏症患者提供了及时缓解作用。 在谈到公司的可持续发展目标时，保曼解释到： “ 在 2022 年，我们再次成功减少了公司的温室气体排放量，同时实现了业务的强劲增长。 ” 他指出，公司的努力正获得越来越多的认可， MSCI 已将拜耳的环境、社会和公司治理（ ESG ）评级由 “ BB ” 提升到 “ A ” 。此外，公司首次在知名的“药品可及性指数”排行榜（ Access to Medicine Index ）中位列前十名，保曼补充到。该排行榜根据公司在中低收入国家的相关努力进行排名。他提到，拜耳在实现其宏大的社会责任目标方面也正取得良好进展。到 2030 年，公司的目标是每年支持中低收入国家 的 1 亿小农户为自己和他人提供生计，每年为中低收入国家的 1 亿女性提供现代避孕产品，每年帮助欠发达 地区的 1 亿民众赋能健康每一天。 如欲了解更多信息，敬请访问： www.bayer.com 。 前瞻性声明 本新闻稿包括拜耳集团管理层基于当前设想和预测所作的前瞻性声明。各种已知和未知的风险、不确定性和其它因素均可能导致公司未来的实际运营结果、财务状况、发展或业绩与上述前瞻性表述中所作出的估计产生重大差异。这些因素包括在拜耳官方网站 www.bayer.com 上公开的拜耳各项报告。本公司没有责任更新这些前瞻性声明或使其符合未来发生的事件或发展。