Tretinoin

推动年轻群体痤疮外用药治疗理念科学普及 武汉 2024年4月22日 /美通社/ -- 4月20日，由中国康复医学会皮肤病康复专业委员会发起、赫力昂中国支持的中国首个基于医患诊疗现状和患者需求编写的专家科普类项目——《2024中国年轻群体痤疮外用药治疗白皮书》（以下简称《白皮书》）正式发布。此举旨在推动社会年轻群体对痤疮规范用药的重视，为患者提供科学用药指引和正确治疗预期，帮助患者早日走出治疗认知误区，焕发人生自信光芒。 《2024中国年轻群体痤疮外用药治疗白皮书》正式发布 聚焦痤疮患者治疗困境，痤疮外用药科普白皮书行业首发 痤疮是一种常见的慢性皮肤疾病，好发于年轻群体中，已成为全球第八大慢性疾病 [1] 。痤疮伴发或治疗后出现的皮肤敏感，以及痤疮遗留的炎症性红斑、色素沉着和瘢痕等后遗症，严重影响了患者尤其是年轻患者的容貌和身心健康 [2] 。有数据表示，56%的患者因痤疮而感到自卑，53%的患者的正常社交受到影响 [3] 。然而，患者虽备受疾病困扰，却对痤疮的诱因和正确应对存在认知误区。以治疗方式为例，97%的医生在痤疮治疗中采用外用药治疗方案，而只有56%的患者倾向于使用外用药物进行治疗。此外，患者常因缺少规范化治疗理念、用药依从性低、缺少外用药治疗意识、以及治疗预期过高等问题，错过痤疮治疗黄金期，从而导致症状加重和反复发生，留下顽固的痤疮后遗症如瘢痕等。 针对患者痤疮治疗痛点，赫力昂支持中国康复医学会皮肤病康复专业委员会展开深入调研并发布《白皮书》。作为中国首个基于医患诊疗现状和患者需求编写的专家科普类项目，《白皮书》面向广大年轻痤疮患者，从问题现状、行为需求、专家建议等多维度进行深入调研，先后在全国范围内调研了1000名痤疮患者、深度采访了上百位皮肤科医生，并邀请了7位皮肤科权威专家全程指导，旨在针对患者痛点，提供权威规范的诊疗知识和建议，帮助减轻痤疮所带来的困扰。 专业战"痘"，健康相"邦" 权威科普指南指导科学治疗，正确选择外用药战"痘" 外用药物治疗是痤疮的基础治疗。《中国痤疮治疗指南(2019)》中指出，外用维A酸是轻中度痤疮治疗及维持治疗的一线选择，而阿达帕林为第三代维A酸，被建议用作轻中度痤疮治疗及维持治疗的一线首选用药 [4] 。《白皮书》中提到，阿达帕林具有溶解粉刺、改善角化、局部抗炎、减轻痘痕的作用 [5] 。 然而，部分患者往往对外用药起效时间的预期过于急迫，一旦无法达到预期就过早停用，因而可能导致疾病转变为中重度，加大治疗难度。针对疾病管理与科学用药问题，《白皮书》中强调，痤疮是慢性皮肤疾病，患者应做好长期战"痘"的准备，坚持规范用药。以阿达帕林为例，轻度痤疮的治疗周期快则需要几周，慢则几月。同时，在使用药物时需注意在痤疮好发部位涂抹，并循序渐进建立耐受，严格遵循医生的规范化治疗方案，才能有效战"痘"。 百多邦品牌促进规范化用药理念建立，持续守护消费者皮肤健康 作为全球消费健康领域的领跑者，赫力昂旗下众多品牌已服务中国消费者近四十年，致力于为中国消费者带来更多创新的健康管理解决方案，改善消费者日常健康状况。百多邦作为赫力昂旗下专注皮肤健康领域的领导品牌，竭力为深受痤疮困扰的消费者提供行之有效的解决方案。 赫力昂中国非处方药事业部总经理、中美史克总经理张展红先生于《白皮书》发布活动上致辞 赫力昂中国非处方药事业部总经理、中美史克总经理张展红表示："百多邦品牌始终专注皮肤健康领域，深耕中国市场三十余年，旗下产品受到了市场的认可与消费者的信赖。针对中国患者对痤疮治疗的迫切需求，百多邦品牌于今年强势入局痤疮治疗领域，致力于为中国患者提供有效的痤疮治疗方案。面向未来，百多邦品牌将携手多方合作伙伴，传播痤疮外用药权威科普指南，助力患者建立规范用药理念，正确用药，早日远离痤疮困扰。" 如今，中国皮肤健康市场正处于高速发展阶段，未来发展潜力巨大。赫力昂将持续完善其在皮肤健康领域的战略布局，聚力赋能更多中国年轻群体。同时，助推中国皮肤健康领域高质量发展，为"健康中国2030"目标早日实现注入强大力量。 [1] 中华医学会, 中华医学会杂志社, 中华医学会皮肤性病学分会, 等.寻常痤疮基层诊疗指南（2023年） [J] . 中华全科医师杂志, 2023, 22(2) : 138-145. DOI: 10.3760/cma.j.cn114798-20221121-01095. [2] 中国痤疮治疗指南专家组. 中国痤疮治疗指南(2019修订版)[J]. 临床皮肤科杂志, 2019, 48(09): 583-588. [3] 中国康复医学会皮肤病康复专业委员会.《2024中国年轻群体痤疮外用药治疗白皮书》P7 [4] 中国痤疮治疗指南专家组.《中国痤疮治疗指南(2019) 》临床皮肤科杂志.2019.48(9):583-588. [5] 中国康复医学会皮肤病康复专业委员会.《2024中国年轻群体痤疮外用药治疗白皮书》P29

From the makers of BOTOX® Cosmetic, two new SkinMedica® acne products help address skin blemishes and can be combined with in-office DiamondGlow® IRVINE, Calif., April 9, 2024 /PRNewswire/ -- Allergan Aesthetics, an AbbVie company (NYSE: ABBV), today announced the launch of two new products from SkinMedica® by the makers of BOTOX® Cosmetic. The SkinMedica® Acne Clarifying Treatment and SkinMedica® Pore Purifying Gel Cleanser are breakthroughs in skincare, providing effective and balanced care for people with acne-prone skin. The two products, along with the SkinMedica® Pore Purifying Pro-Infusion Serum, used in-office with DiamondGlow®, complete the protocol, providing acne sufferers a continuum of products to help address their skin concerns. "Acne is the most common skin concern in the US.1 It is also the primary reason patients schedule an office visit with their provider.2 For 25 years, SkinMedica® has been dedicated to perfecting scientifically proven skincare that yields visible results," said Jasson Gilmore, Senior Vice President, U.S. Aesthetics. "The formulations of the new products continue the legacy of promoting skin health and addressing key patient concerns like acne." In clinical studies, participants who used the SkinMedica® Acne Clarifying Treatment and Pore Purifying Gel Cleanser noticed clearer skin while reporting that the products did not dry their skin out. Additionally, clinical study participants noted the treatment regimen helped calm their skin.3 The SkinMedica® approach to addressing acne focuses on efficacy while respecting the skin barrier to help break the acne cycle by balancing sebum, soothing visible redness, and preserving the microbiome. "Navigating the challenges posed by acne can be difficult, and most acne products are effective at targeting acne but ignore the impact of the ingredients on the skin barrier," said Dr. Mona Gohara, board-certified dermatologist and associate clinical professor at Yale University. "My patients often find themselves in a bind when choosing acne products that treat acne but don't compromise the skin barrier. I am excited to offer my patients these new products from SkinMedica®, which focus on sebum regulation and barrier protection to create a desirable balance of low irritation with strong efficacy." The SkinMedica® Acne Clarifying Treatment is formulated with 2% encapsulated salicylic acid, which proactively guards against future breakouts. The product also includes ingredients like niacinamide and bakuchiol, which work together to reduce the appearance of discoloration and post-acne marks while refining pores and enhancing skin tone. With each application, this treatment becomes a shield, preserving the skin's natural barrier. MSRP $66. Complementing the Acne Clarifying Treatment is the SkinMedica® Pore Purifying Cleanser, which is infused with salicylic acid, a beta-hydroxy acid, to help remove impurities while a potent blend of antioxidants and soothing botanicals like aloe and chamomile caress the skin, leaving behind a soft and refreshed canvas. MSRP $46. The new SkinMedica® products are available for purchase at SkinMedica.com and through a network of licensed physicians and medically supervised spas. To experience the SkinMedica® Pore Purifying Pro-Infusion Serum for DiamondGlow®, find a provider by visiting DiamondGlow.com. For more information follow @SkinMedica on Instagram. About Allergan Aesthetics At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook, Instagram, X (formerly Twitter), and YouTube. Forward-Looking Statements Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, and changes to laws and regulations applicable to our industry. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2023 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its subsequent Quarterly Reports on Form 10-Q. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law. DiamondGlow® Uses The DiamondGlow® device is a general dermabrasion device that gently removes the top layer of skin and delivers topical cosmetic serums onto the skin. DiamondGlow® Important Safety Information The DiamondGlow® treatment is not for everyone. You should not have a DiamondGlow® treatment if you have compromised skin quality. Tell your provider if you are pregnant or lactating, or if you have any medical conditions, including allergies, and if you are using topical medications on the area to be treated. Typical side effects include a scratchy, stinging sensation during the treatment and temporary tightness, redness or slight swelling after the treatment. Rare serious side effects may also occur and include severe skin irritation and allergic reactions. SkinMedica® Pro-Infusion Serums Disclaimer SkinMedica® Pro-Infusion Serums are intended to meet the FDA's definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These products are not intended to be drugs that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA and the statements have not been evaluated by the FDA. Please talk to your provider for additional information. SkinMedica® Important Information Most SkinMedica® products are intended to meet the FDA's definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA and the statements have not been evaluated by the FDA. SkinMedica® Acne Clarifying Treatment is an over-the-counter drug product which is formulated and marketed pursuant to FDA's governing regulations set forth at 21 CFR Part 333 Subpart D. For more information, please talk to your provider or visit SkinMedica.com and DiamondGlow.com. To report an adverse reaction, please call Allergan at 1-800-433-8871. BOTOX® COSMETIC IMPORTANT SAFETY INFORMATION AND APPROVED USES IMPORTANT SAFETY INFORMATION BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic: Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months. Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing. BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product. There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow's feet lines, and/or forehead lines. BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities. Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint. Do not receive BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site. Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig's disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic. Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk). Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past. Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners. Other side effects of BOTOX® Cosmetic include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of your eyelids and dry eyes. Approved Uses BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow's feet lines, and frown lines between the eyebrows in adults. For more information refer to the Medication Guide or talk with your doctor. To report a side effect, please call Allergan at 1-800-678-1605. Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide. References: AAD () Kline. Prograde Skincare Report. 2022.(According to Kline's Physician-Dispensed Skin Care: US Perception and Satisfaction Survey 2022, physicians noted that acne was the most common skin condition that patients visit physician's office for, followed by fine lines/wrinkles, sagging skin, and pigmentation.) Data on file at SkinMedica ® SOURCE AbbVie