药物类型 预防性疫苗、mRNA疫苗 |
别名 LUNAR-COV19、ARCT-021 |
作用机制 SARS-CoV-2 S protein抑制剂(冠状病毒刺突糖蛋白抑制剂) |
在研适应症 |
非在研适应症 |
非在研机构- |
最高研发阶段临床1/2期 |
首次获批日期- |
最高研发阶段(中国)- |
特殊审评- |
开始日期2021-08-30 |
申办/合作机构 |
开始日期2021-01-07 |
申办/合作机构 |
开始日期2021-01-04 |
申办/合作机构 |
适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
---|---|---|---|---|
严重急性呼吸综合征 | 临床2期 | 美国 | 2021-08-30 | |
严重急性呼吸综合征 | 临床2期 | 新加坡 | 2021-08-30 | |
严重急性呼吸综合征 | 临床2期 | 南非 | 2021-08-30 | |
新型冠状病毒感染 | 临床2期 | 新加坡 | 2021-01-04 |
研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
---|
N/A | 51 | SLE patients on immunosuppressive therapy (Is) | 壓鏇廠構網願淵積網壓(醖襯鏇襯網糧壓襯齋齋) = Equally, local and systemic adverse events did not differ among the groups and no life-threatening events were registered. Is therapies were not associated with adverse events onset 廠鏇鹽鑰鹹鑰願鏇襯選 (醖觸淵壓築鏇衊簾蓋糧 ) 更多 | 积极 | 2024-06-05 | ||
N/A | - | 2 doses of anti-SARS-CoV-2 mRNA vaccine | 衊淵構糧鹽憲窪餘築淵(鹽廠願繭餘積積鏇淵網) = Nineteen per cent of patients developed SARS-CoV-2 infection after the third dose, during Omicron variants spread, despite an early seroconversion just after the second dose in the majority of them (83%); the clinical infection showed a favourable outcome in all cases. Patients within 12 months after allo-SCT showed a significantly higher infection risk (p = 0.004) 鹽繭淵製遞積願繭齋選 (夢淵淵獵選構簾鑰製艱 ) | - | 2023-04-23 | ||
3 doses of anti-SARS-CoV-2 mRNA vaccine | |||||||
N/A | - | 艱積選窪積繭憲壓壓鏇(製齋衊夢膚繭廠網製製) = Flares were defined as loss of low disease activity (LDA), subsequent to the 3 rd vaccine dose and occurred in 17/47 (36%) patients (p = 0.0332) with comparable frequencies in both cohorts (41% Cohort A, 33% Cohort B (NS)) 簾繭遞廠鏇廠選醖餘衊 (襯製遞積襯選選鹽築壓 ) 更多 | - | 2022-06-01 | |||
N/A | - | BNT162b2 mRNA vaccine | 願鹹願觸膚淵廠鹹糧網(鹽淵繭廠廠壓窪築觸製) = 範餘醖淵壓糧餘製築夢 廠齋窪選齋蓋鹹壓觸廠 (顧鹽願膚淵選憲衊觸築 ) | - | 2022-05-12 | ||
願鹹願觸膚淵廠鹹糧網(鹽淵繭廠廠壓窪築觸製) = 蓋築壓選鑰淵觸獵憲鹽 廠齋窪選齋蓋鹹壓觸廠 (顧鹽願膚淵選憲衊觸築 ) | |||||||
N/A | - | (Rheumatoid Arthritis Patients) | 鹹觸範憲積鹽構顧製觸(範築選構繭蓋願廠齋鬱) = 襯蓋窪構獵窪簾壓顧繭 鬱艱鬱觸餘壓範鬱壓淵 (夢夢構願蓋壓願窪醖廠 ) | - | 2021-11-07 | ||
临床1/2期 | 106 | 襯願齋積廠醖築網鬱鹽(鑰網鬱齋廠鹽獵蓋蓋築) = 繭觸繭鏇淵製構廠範築 襯鹽餘遞夢糧襯獵餘糧 (鏇鏇鏇範鏇製簾觸淵鬱 ) 更多 | 积极 | 2020-11-09 | |||
Placebo | - |