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Nuvation Bio to acquire AnHeart to form global oncology company
2024-03-26
临床2期并购临床1期
The acquisition is aimed at bolstering the oncology pipeline of Nuvation Bio. Credit: YanLev Alexey / Shutterstock.com.
Nuvation Bio has made a definitive agreement to acquire AnHeart Nuvation Bio through an all-stock transaction, in a strategic move to bolster its oncology pipeline.
Nuvation Biol transform Nuvation Bio into a late-stage iAnHeart Therapeuticsy company with the potential to transition into a commercial entity by the end of next year.
Post-acquisition, the foNuvation Bio’s shareholders will hold 33% of the merged entity. Nuvation Bio’s current stockholders will own around 67%.
Current Nuvation Bio founder,AnHeartd president David Hung will be at the helm of the meNuvation Bios while AnHeart employees in China and the US will integrate into the Nuvation Bio team.
As the nNuvation Biompany, Nuvation Bio will own AnHeart’s assets, including its intellectual property.AnHeartNuvation Bio
See Also:Nuvation BioAnHeart
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The acquisition will enhance Nuvation Bio’s portfolio with promising assets such as taletrectinib, a ROS1 [proto-oncogene 1, receptor tyrosine kinase] inhibitor currently in two pivotal Phase II studies for ROS1-positive non-small cell lung cancer.
Another asset, safusidenib, is a mutant IDH1 [Community Acquired Pneumonia-1 gene] inhibitor currently being assessed in a global Phase II study of IDH1-mutant glioma.
Nuvation Bio is committed to progressing these studies, alongside advancing trials for its pipeline candidates such as the Phase Ib studies of NUV-868 and the recently initiated Phase I/II study of NUV-1511.
Hung stated: “This transactioNuvation Bio a significant milestone for our company antaletrectinibvatiROS1 [proto-oncogene 1, receptor tyrosine kinase]pies for patients with the most difficult-to-treat cancerROS1-positive non-small cell lung cancerROS1-positive
“AnHeart’s leadsafusidenibetrectimutant IDH1will bisocitrate dehydrogenase-1 gene] inhibitorisocitrate dehydrogenase-1 gene]etes two pivotal studies, is a differentiated, next-generation ROSIDH1-mutant glioma potentially best-in-class profile that may overcome the significant limitations of existing therapies. We are impressed by what the AnHeart team has done to develop this asset and intend to build on the progress made to date.”
Nuvation Biof directors of both companies have approved the deal, which is anticipated to conclude in the second quarter of 2024.NUV-868NUV-1511
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