The standard for the quality control of Shuxinning capsules was established. Ligusticum wallichii and Salvia were identified qualititatively by thin-layer chromatog. (TLC). Paeoniflovin in Shuxinning capsules was determined by HPLC, the chromatog. conditions were as follows: the detection wavelength was 230 nm. The TLC spots were highly clear without the interference of neg. control. The calibration curve for paeoniflovin was linear (r=1.0000) in the range of 20 μg-140 μg, and the mean recovery was 99.47%, RSD was 1.27%. This method is accurate, simple, sensitive and reliable and it can be used for the quality control of Shuxinning capsules.