Suzhong Pharma Group Co. Ltd.

Huangkui Capsule is a single medicament of traditional Chinese medicine consists of Abelmoschus manihot and has been widely used to treat kidney disease. The purpose of this study is to evaluate the safety and efficacy of Abelmoschus manihot for treating chronic kidney disease in large scale samples with long time take.

-IgA nephropathy is the most common primary glomerular disease in China, Huangkui Capsule is a single medicament of traditional Chinese medicine consists of Abelmoschus manihot and has been widely used to treat kidney disease. The purpose of this study is to evaluate the safety and efficacy of Abelmoschus manihot for treating IgA nephropathy in large scale samples with long time take.

主要目的：评价马来酸苏特替尼胶囊对比含铂双药化疗治疗局部晚期或转移性EGFR非经典突变NSCLC患者的无进展生存期（PFS，由独立中心影像[IRC]评估，基于实体瘤疗效评价标准第1.1版[RECIST 1.1]）。 次要目的：评价马来酸苏特替尼胶囊对比含铂双药化疗的PFS（基于研究者评估）；总生存期（OS）；以及基于IRC评估的：客观缓解率（ORR）、缓解持续时间（DOR）、疾病控制率（DCR）、临床获益率（CBR）。评价马来酸苏特替尼胶囊对比含铂双药化疗治疗局部晚期或转移性NSCLC患者的安全性和耐受性。