预约演示
更新于：2026-02-10
Zhejiang Chinese Medical University
更新于：2026-02-10
概览
标签
肿瘤
消化系统疾病
心血管疾病
蛋白水解靶向嵌合体（PROTAC）
小分子化药
多糖药物
疾病领域得分
一眼洞穿机构专注的疾病领域
技术平台
公司药物应用最多的技术
靶点
公司最常开发的靶点
关联
靶点 |
作用机制 |
在研机构 |
原研机构 |
在研适应症 |
非在研适应症 |
最高研发阶段 |
首次获批国家/地区 |
首次获批日期 |
靶点 |
作用机制 |
在研机构 |
原研机构 |
在研适应症 |
非在研适应症 |
最高研发阶段 |
首次获批国家/地区 |
首次获批日期 |
靶点 |
作用机制 |
在研机构 |
原研机构 |
在研适应症 |
非在研适应症 |
最高研发阶段 |
首次获批国家/地区 |
首次获批日期 |
ITMCTR2025002486
The Efficacy and Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation in Preventing Postoperative Nausea and Vomiting in High-Risk Gynecological Laparoscopic Surgery Patients: A Randomized Controlled Trial
NCT07394647
Transcutaneous Auricular Vagus Nerve Stimulation for Preventing Emergence Agitation and Delirium After Pediatric Tonsillectomy and Adenoidectomy: A Randomized, Double-Blind, Interventional Study
ChiCTR2600118070
Clinical study of mesenchymal stem cell-derived exosomes combined with conventional therapy in the treatment of allergic rhinitis
100 项与 浙江中医药大学 相关的临床结果
登录后查看更多信息
登录后查看更多信息
2026-12-31DRUG DELIVERY
Nanotherapeutics for enhanced treatments for ovarian cancer: a comprehensive minireview
Review
作者: Li, Binting ; Xu, Keyi ; Zhang, Ting ; Xu, Xiaotong
As one of the most lethal gynecological malignancies, ovarian cancer (OC) significantly impacts the health and quality of life of women globally. Currently, surgical intervention and chemotherapy remain the primary clinical treatment modalities for OC. With ongoing advancements in the understanding of molecular mechanisms, various therapeutic strategies such as poly-ADP-ribose polymerase inhibitors (PARPi) treatment, immunotherapy, and combination therapies have also been introduced into clinical practice. However, significant challenges, such as systemic adverse effects, high recurrence rates, and the development of drug resistance, greatly limit their efficacy. To overcome these limitations, nanotherapeutics have emerged as promising multifunctional drug delivery systems for both the diagnosis and treatment of OC over the past few decades, owing to their ability to specifically target malignant tissues and enable controlled drug release. In this paper, we first review the tumor-targeting mechanisms of nanoparticles, which can guide researchers in designing suitable and effective nanomedicines with translational potential. We subsequently provide a detailed overview of several representative nanotherapeutic approaches used in the treatment of OC, including their roles in enhancing chemotherapy, PARPi therapy, immunotherapy, light- or ultrasound-mediated therapies, and various combination strategies. Finally, we discuss future perspectives and potential directions for nanotherapeutics in advancing personalized and targeted treatment of OC.
2026-12-31Human Vaccines & Immunotherapeutics
Perceived risk and time costs as correlates of hepatitis vaccine hesitancy among Chinese university students: A ten‑university cross‑sectional study
Article
作者: Wang, Qi ; Fu, Chuanxi ; Gao, Hong ; Chen, Peihang ; Wen, Hongling ; Wang, Hongni ; Yang, Haiyan ; Dong, Xiaomei ; Li, Hong ; Li, Zhenwei ; Sun, Caijun ; Xu, Binyue ; Jiang, Minghuan ; Chen, Yingqi
To estimate the prevalence of hepatitis vaccine hesitancy among Chinese university students and identify modifiable correlates to guide campus programs. We ran a multicampus cross-sectional survey (December 2023-February 2024) using a two-stage stratified cluster design across eastern, central, and western China. Hesitancy was measured with an 11 item hepatitis-adapted Vaccine Hesitancy Scale (α = 0.83). Multivariable logistic regression examined Health Belief Model constructs and convenience (travel/visit time). Among 2526 respondents, 51.8% met the prespecified hesitancy threshold. Seniors were more hesitant than juniors (aOR = 1.55, 95% CI: 1.25-1.91); students in the central region exceeded those in the east (1.30, 1.07-1.59). Off-campus residence (0.58, 0.41-0.83) and non-medical majors (0.68, 0.54-0.85) had lower odds. Higher perceived risk was also associated with lower hesitancy (0.66, 0.55-0.78). Ordering takeout showed a dose - response (e.g. 3-4/week vs never: 2.52, 1.67-3.82), whereas sharing tableware/drinkware was inversely associated (e.g., 3-4/week vs never: 0.38, 0.23-0.63). Time costs mattered: travel time >30 minutes was linked to higher hesitancy (1.43, 1.06-1.94), and unclear visit duration was also associated (1.40, 1.02-1.93). Hepatitis vaccine hesitancy is common among university students. Two modifiable levers - risk perception and service convenience - support highyield campus strategies.
2026-06-01International Journal of Pharmaceutics-X
Application of ultrasound and ultrasound-responsive materials in wounds: A systematic review
Review
作者: Song, Liwan ; Gao, Jianqing ; Ma, Xiaolu ; Yang, Gaoyi ; Luo, Ying ; Luo, Jialei ; Yan, Xinyi
Wound healing is a multifaceted biological process that is highly susceptible to disruption by numerous internal and external factors, resulting in delayed tissue repair. Recent advancements have highlighted the therapeutic potential of ultrasound, especially when integrated with emerging smart materials, which together offer promising strategies for enhancing wound care outcomes. Low- and high-intensity ultrasound (US) use mechanisms such as cavitation, acoustic streaming, and radiation forces to disrupt biofilms, improve drug permeability, and promote tissue regeneration. When combined with US-responsive materials, such as scaffolds, piezoelectric composites, microbubbles, microneedles, and flexible patches, these systems enable targeted functions, including controlled drug release, antimicrobial activity, and enhanced deep tissue penetration. These responsive materials effectively overcome the limitations of conventional wound dressings, which often suffer from poor drug bioavailability, susceptibility to infection, and a lack of personalized therapeutic capabilities. This review systematically explores 5 categories of advanced materials, with a focus on their synergistic interactions with ultrasound to enhance wound healing outcomes. By elucidating the interactions between material-US and their translational implications, this review offers new perspectives to advance the clinical development of precision-based, next-generation wound therapies.
100 项与 浙江中医药大学 相关的药物交易
登录后查看更多信息
100 项与 浙江中医药大学 相关的转化医学
登录后查看更多信息
组织架构
使用我们的机构树数据加速您的研究。
登录
或
管线布局
2026年02月28日管线快照
管线布局中药物为当前组织机构及其子机构作为药物机构进行统计，早期临床1期并入临床1期，临床1/2期并入临床2期，临床2/3期并入临床3期
药物发现
12
71
临床前
其他
2
登录后查看更多信息
当前项目
登录后查看更多信息
药物交易
使用我们的药物交易数据加速您的研究。
登录
或
转化医学
使用我们的转化医学数据加速您的研究。
登录
或
营收
使用 Synapse 探索超过 36 万个组织的财务状况。
登录
或
科研基金(NIH)
访问超过 200 万项资助和基金信息，以提升您的研究之旅。
登录
或
投资
深入了解从初创企业到成熟企业的最新公司投资动态。
登录
或
融资
发掘融资趋势以验证和推进您的投资机会。
登录
或
生物医药百科问答
全新生物医药AI Agent 覆盖科研全链路，让突破性发现快人一步
立即开始免费试用!
智慧芽新药情报库是智慧芽专为生命科学人士构建的基于AI的创新药情报平台，助您全方位提升您的研发与决策效率。
立即开始数据试用!
智慧芽新药库数据也通过智慧芽数据服务平台，以API或者数据包形式对外开放，助您更加充分利用智慧芽新药情报信息。
生物序列数据库
生物药研发创新
免费使用
化学结构数据库
小分子化药研发创新
免费使用