Oxyrane UK Ltd.

A review.The details of several case studies illustrating how Oxyrane's inhouse epoxide hydroxylase (EH) technol. has been applied up to kilogram scale in a range of racemic epoxide resolutions are presented.These case studies have been selected to demonstrate how the traditional constraints of biocatalytic technologies - such as restricted substrate flexibility specialised reactor requirement and low volumetric yields - have been overcome by the inherent robustness of the EH platform.