Delving into the Latest Updates on Gunma University School of Medicine with Synapse

Verification of the effectiveness of an educational program aimed at alleviating nurses' difficulties in communication regarding death with cancer patients at the end-of-life stage - Communication nursing education program

开始日期2024-04-01

申办/合作机构

Gunma University School of Medicine

JPRN-UMIN000052121 / SuspendedIIT

Effects of massage (circulation-promoting stimulation) for relief of cold symptoms in women with cold sensitivity -pre and post comparative trial of self-hand massage and ear massage- - Effects of massage (circulation-promoting stimulation) for relief of cold symptoms in women with cold sensitivity -pre and post comparative trial of self-hand massage and ear massage-

开始日期2023-09-15

申办/合作机构

Gunma University School of Medicine

JPRN-UMIN000047331 / SuspendedIIT

Shared decision making on dialysis modality selection in Japan: a cross-sectional study - Shared decision making on dialysis modality selection in Japan: a cross-sectional study

开始日期2022-05-16

申办/合作机构

Gunma University School of Medicine

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7,018

项与 Gunma University School of Medicine 相关的文献（医药）

2024-12-31·NMC Case Report Journal

Thoracic Intra and Extramedullary Capillary Hemangioma with Subacute Clinical Course: A Case Report and Literature Review

作者: Honda, Fumiaki ; Shirakura, Takahiro ; Yamamoto, Yumeki ; Shimauchi-Ohtaki, Hiroya ; Yokoo, Hideaki ; Miyagishima, Takaaki ; Shintoku, Ryosuke ; Aihara, Masanori ; Aramaki, Keigo ; Yoshimoto, Yuhei

Capillary hemangiomas are benign tumors comprising a lobulated proliferation of capillary vessels frequently located in the soft tissues of the neck and head. Spinal intradural capillary hemangiomas are rare, particularly intramedullary lesions. To our knowledge, only 31 cases of spinal intramedullary capillary hemangiomas have been reported. Here, we describe a rare case of a thoracic capillary hemangioma comprising extramedullary and intramedullary components. A 51-year-old male patient presented with bilateral lower extremity numbness and subsequent paraparesis, sensory disturbance, and bladder-bowel dysfunction with a subacute clinical course. Magnetic resonance imaging revealed a mass lesion with intramedullary and intradural extramedullary components at the Th9-10 vertebrae level and widespread spinal cord edema. Contrast-enhanced computed tomography revealed abnormal vessels on the dorsal spinal cord surface. Spinal angiography revealed a light-stained mass lesion fed by the radiculopial artery from the right Th11 intercostal artery. The tumor was resected en bloc, and the histological diagnosis was a capillary hemangioma. Postoperatively, the spinal cord edema diminished, and the patient was discharged from the convalescent rehabilitation ward. Although intramedullary capillary hemangioma is a rare spinal tumor and its preoperative diagnosis is difficult, it should be considered in the differential diagnosis of spinal intramedullary tumors.

2024-11-01·International Journal of Clinical Oncology

Current status and prospects of artificial intelligence in breast cancer pathology: convolutional neural networks to prospective Vision Transformers

Review

作者: Watanabe, Yukako ; Rakha, Emad A ; Aoki, Yuki ; Katayama, Ayaka ; Horiguchi, Jun ; Oyama, Tetsunari

Breast cancer is the most prevalent cancer among women, and its diagnosis requires the accurate identification and classification of histological features for effective patient management. Artificial intelligence, particularly through deep learning, represents the next frontier in cancer diagnosis and management. Notably, the use of convolutional neural networks and emerging Vision Transformers (ViT) has been reported to automate pathologists' tasks, including tumor detection and classification, in addition to improving the efficiency of pathology services. Deep learning applications have also been extended to the prediction of protein expression, molecular subtype, mutation status, therapeutic efficacy, and outcome prediction directly from hematoxylin and eosin-stained slides, bypassing the need for immunohistochemistry or genetic testing. This review explores the current status and prospects of deep learning in breast cancer diagnosis with a focus on whole-slide image analysis. Artificial intelligence applications are increasingly applied to many tasks in breast pathology ranging from disease diagnosis to outcome prediction, thus serving as valuable tools for assisting pathologists and supporting breast cancer management.

2024-11-01·Gastric Cancer

Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)

Article

作者: Nakazawa, Nobuhiro ; Urakawa, Naoki ; Honboh, Takuya ; Iwasaki, Hironori ; Yasufuku, Itaru ; Saeki, Hiroshi ; Hatakeyama, Satoru ; Kusumoto, Tetsuya ; Imai, Yoshiro ; Oki, Eiji ; Hiki, Naoki ; Sohda, Makoto ; Bamba, Takeo ; Arai, Junichi ; Shirabe, Ken ; Kuwabara, Shirou ; Baba, Hideo ; Sano, Akihiko ; Sakai, Makoto ; Yamaguchi, Takahisa ; Shinno, Naoki ; Kawashima, Yoshiyuki ; Shibao, Kazunori ; Sakon, Masahiro ; Koga, Tadashi ; Enokida, Yasuaki ; Kawaguchi, Yoshihiko ; Tokunaga, Masanori ; Yamamoto, Manabu ; Tsukada, Tomoya

BACKGROUNDThe significance of reinforcement of the duodenal stump with seromuscular sutures and the effectiveness of reinforced staplers in preventing duodenal stump leakage remain unclear. We aimed to explore the importance of duodenal stump reinforcement and determine the optimal reinforcement method for preventing duodenal stump leakage.METHODSThis retrospective cohort study was conducted between January 1, 2012 and December 31, 2021, with data analyzed between December 1, 2022 and September 30, 2023. This multicenter study across 57 institutes in Japan included 16,475 patients with gastric cancer who underwent radical gastrectomies. Elective open or minimally invasive (laparoscopic or robotic) gastrectomy was performed in patients with gastric cancer.RESULTSDuodenal stump leakage occurred in 153 (0.93%) of 16,475 patients. The proportions of males, patients aged ≥ 75 years, and ≥ pN1 were higher in patients with duodenal stump leakage than in those without duodenal stump leakage. The incidence of duodenal stump leakage was significantly lower in the group treated with reinforcement by seromuscular sutures or using reinforced stapler than in the group without reinforcement (0.72% vs. 1.19%, p = 0.002). Duodenal stump leakage incidence was also significantly lower in high-volume institutions than in low-volume institutions (0.70% vs. 1.65%, p = 0.047). The rate of duodenal stump leakage-related mortality was 7.8% (12/153). In the multivariate analysis, preoperative asthma and duodenal invasion were identified as independent preoperative risk factors for duodenal stump leakage-related mortality.CONCLUSIONSThe duodenal stump should be reinforced to prevent duodenal stump leakage after radical gastrectomy in patients with gastric cancer.

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