Review
作者: Ajami, Negar ; Mohammadi Visroud, Mozhdeh ; Hosseini, Zahrasadat ; Mirbolook, Amirhossein ; Momeni, Zahra ; Manavi, Mahdokht Sadat ; Zahedpasha, Reza ; Hoorshad, Behnam ; Fallahian, Amirali ; Goodarzy, Babak ; Alipour Khabir, Yalda ; Moghadam Fard, Atousa ; Safdari, Sina ; Tavakoli, Reza ; Seifi, Sepideh ; Ranjbar, Ehsan ; Najafi, Aboulfazl ; Afrazeh, Fatemeh ; Momeni, Hamidreza ; Jalayeri, Hediyeh ; Azimi, Habib ; Mahjoubi, Mohammad ; Kahrizi, Mohammad Saeed ; Amani Beni, Reza ; Ghalichebaf Yazdi, Yeganeh ; Rahmani, Erfan ; Aboulhassanzadeh, Sobhan ; Ghadirzadeh, Erfan ; Esmaili Jobani, Alireza ; Bakhtiyari, Paria ; Ramezani, Sahel ; Hosseini, Mohammad Hossein ; Zare Lahijan, Lida ; Atighi, Javaneh ; Alipour Khabir, Sevda ; Tavakoli, Mehdi ; Farrokhi, Mehrdad ; Ranjbaran Ghaleh, Mohadese
IntroductionForeign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identification of FBA in children.MethodsFrom inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2).ResultsThe systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98-0.99) and 0.97 (95% CI: 0.96-0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59-22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02-0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98.ConclusionOur meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases.