α-synuclein

Company to host conference call on Thursday, March 28, 2024 at 8:00 a.m. ETBOSTON and ATLANTA, March 27, 2024 (GLOBE NEWSWIRE) -- Inhibikase Therapeutics, Inc. (Nasdaq: IKT) (Inhibikase or Company), a clinical-stage pharmaceutical company developing protein kinase inhibitor therapeutics to modify the course of Parkinson’s disease (“PD”), Parkinson’s-related disorders and other diseases of the Abelson Tyrosine Kinases, today reported financial results for the fourth quarter and full year ended December 31, 2023 and highlighted recent developments. “2023 was a year of clinical execution across our pipeline, culminating in the recent pre-NDA meeting with the FDA for IkT-001Pro and robust enrollment of untreated Parkinson’s patients in our 201 Trial evaluating Risvodetinib (“Risvo”),” said Dr. Milton H. Werner, President and Chief Executive Officer of Inhibikase. “As we look ahead, we believe that FDA feedback from our pre-NDA meeting was constructive as we work on the requirements for NDA submission for IkT-001Pro. In addition, enrollment of patients into the 201 Trial supports our belief that topline data from the three-month, double-blind phase of the study may be available in the second half of this year. Our recent publication of Phase 1 safety, tolerability and pharmacokinetic clinical data for Risvo in the Journal of Parkinson’s Disease reinforces our belief that Risvo is well tolerated and reaches therapeutic exposures in patients with Parkinson’s disease and related disorders. We look forward to taking advantage of the recent momentum we have experienced as we continue to build value for our shareholders and bring new medicines to patients in need.” Recent Developments and Upcoming Milestones: Completed Pre-NDA Meeting with the FDA for IkT-001Pro: On January 19, 2024, Inhibikase met with the FDA Review Team (“Review Team”) from the Division of Hematologic Malignancies to discuss requirements for a 505(b)(2) NDA submission for IkT-001Pro in up to 11 blood and stomach cancer indications. Final Meeting Minutes were provided by the FDA on February 12, 2024. The Meeting Minutes confirmed that the 505(b)(2) pathway appears to be appropriate for approval of IkT-001Pro. The Review Team removed the requirement to perform a formal use-related risk assessment but expects the NDA package to justify how medication errors will be avoided for physicians, pharmacists and patients who are prescribed IkT-001Pro. The Company plans to manufacture dosage forms at 150 mg and 300 mg to discriminate IkT-001Pro from the 100 mg and 400 mg dosage forms of imatinib mesylate. These alternative dosage forms do not require any manufacturing process development. In terms of bioequivalence, clinical studies completed to date indicate that imatinib delivered by 600 mg and 800 mg IkT-001Pro provide similar exposures to imatinib delivered by 400 mg and 600 mg imatinib mesylate, respectively. Imatinib mesylate is approved for use between 300 mg and 800 mg once daily for 11 blood or stomach cancers. To cover the range of approved doses of imatinib mesylate, the Company plans to study the 1200 mg dose of IkT-001Pro that is expected to lead to exposures equivalent to 800 mg imatinib. The Review Team also suggested the Company analyze how IkT-001Pro and imatinib mesylate behave with respect to certain gut transporters that regulate absorption from the gastrointestinal tract. Inhibikase is in alignment with the FDA on this point and is initiating the necessary pre-clinical test to compare IkT-001Pro and imatinib mesylate. The Review Team and Company also agreed on the size of drug substance and drug product batches needed to meet the quality control requirements for approval. The Company will request milestone-based meetings as it completes the manufacturing and quality control processes to ensure the Company and the Review Team remain aligned throughout the process. The Company also continues to evaluate the market potential of IkT-001Pro in non-oncology indications to which imatinib has already been shown to have clinical benefit.Actively enrolling patients in the Phase 2 201 Trial of Risvodetinib (IkT-148009) in untreated Parkinson’s disease: As of March 22, 2024, 73 participants have been enrolled, 20 prospective participants are in medical screening and 48 potential participants are being evaluated for suitability to initiate medical screening. Additionally, 34 participants have completed the 12-week dosing period. 15 mild and 2 moderate adverse events that may have been related to Risvo have been reported thus far in the trial. As the trial remains blinded, it is unknown whether any or how many of these mild or moderate adverse events are actually related to Risvo itself. Depending on the enrollment of the last participant, the Company may report topline results from the 201 Trial in the second half of 2024, including measurement of novel biomarker data as it relates to alpha-synuclein aggregates.Published Phase 1 Results of Risvodetinib in the Journal of Parkinson’s Disease: In January 2024, Inhibikase published the results of its Phase 1 clinical studies with Risvo entitled “A Phase I, Randomized, SAD, MAD, and PK Study of Risvodetinib in Older Adults and Parkinson’s Disease,” online in the peer reviewed Journal of Parkinson’s Disease. The publication highlighted data demonstrating that Risvo was well tolerated up to 7 days of daily dosing with no clinically meaningful events in healthy volunteers or worsening of symptoms in participants taking anti-PD medications. Of note, voluntary lumbar puncture was used to measure the concentration of Risvo in cerebrospinal fluid (CSF) in six participants with or without PD. Measures of the CSF concentration of Risvo indicate that it crossed the blood-brain barrier and was persistently present in the central nervous system. Full Year 2023 Financial Results Net Loss: Net loss for the year ended December 31, 2023, was $19.0 million, or $3.57 per share, compared to a net loss of $18.1 million, or $4.28 per share for the year ended December 31, 2022. R&D Expenses: Research and development expenses for the year ended December 31, 2023 were $13.6 million compared to $12.0 million for the full year 2022. The $1.6 million increase was primarily due to a $1.5 million increase in CML expenditures, a decrease of $0.6 million in PD expenses and a net increase of $0.7 million in all other research and development activities. SG&A Expenses: Selling, general and administrative expenses for the year ended December 31, 2023 were $6.7 million compared to $6.2 million for the year ended December 31, 2022. The $0.5 million increase was primarily the result of an increase in investor relations costs of $1.0 million and an increase in employee costs of $0.3 million that were partly offset by a decrease in D&O insurance of $0.6 million, a decrease in legal and consulting fees of $0.4 million and a net increase of $0.2 million in all other selling, general and administrative expenses. Cash Position: Cash, cash equivalents and marketable securities were $13.3 million as of December 31, 2023. The Company expects that existing cash and cash equivalents will be sufficient to fund operations into the first quarter of 2025. Conference Call InformationInhibikase will host a conference call and webcast to discuss its full-year 2023 financial results and business highlights tomorrow, March 28, 2024, at 8:00am ET. The conference call can be accessed by dialing 1-877-407-0789 (United States) or 1-201-689-8562 (International) and referencing Inhibikase Therapeutics. A live webcast may be accessed using the link here, or by visiting the investors section of the Company's website at www.inhibikase.com. After the live webcast, the event will be archived on Inhibikase’s website for approximately 90 days after the call. About Inhibikase (www.inhibikase.com) Inhibikase Therapeutics, Inc. (Nasdaq: IKT) is a clinical-stage pharmaceutical company developing therapeutics for Parkinson's disease and related disorders. Inhibikase's multi-therapeutic pipeline has a primary focus on neurodegeneration and its lead program risvodetinib, an Abelson Tyrosine Kinase (c-Abl) inhibitor, targets the treatment of Parkinson's disease inside and outside the brain as well as other diseases that arise from Abelson Tyrosine Kinases. Its multi-therapeutic pipeline is pursuing Parkinson's-related disorders of the brain and GI tract, orphan indications related to Parkinson's disease such as Multiple System Atrophy, and drug delivery technologies for kinase inhibitors such as IkT-001Pro, a prodrug of the anticancer agent imatinib mesylate that the Company believes will provide a better patient experience with fewer on-dosing side-effects. The Company's RAMP™ medicinal chemistry program has identified several follow-on compounds to risvodetinib that could potentially be applied to other cognitive and motor function diseases of the brain. Inhibikase is headquartered in Atlanta, Georgia with offices in Lexington, Massachusetts. Social Media DisclaimerInvestors and others should note that the Company announces material financial information to investors using its investor relations website, press releases, SEC filings and public conference calls and webcasts. The Company intends to also use X, Facebook, LinkedIn and YouTube as a means of disclosing information about the Company, its services and other matters and for complying with its disclosure obligations under Regulation FD. Forward-Looking StatementsThis press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking terminology such as "believes," "expects," "may," "will," "should," "anticipates," "plans," or similar expressions or the negative of these terms and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on Inhibikase's current expectations and assumptions. Such statements are subject to certain risks and uncertainties, which could cause Inhibikase's actual results to differ materially from those anticipated by the forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements include our ability to enroll and complete the 201 Trial evaluating risvodetinib in untreated Parkinson’s disease, to successfully apply for and obtain FDA approval for IkT-001Pro in blood and stomach cancers or other indications, to successfully conduct clinical trials that are statistically significant and whether results from our animal studies may be replicated in humans, as well as such other factors that are included in our periodic reports on Form 10-K and Form 10-Q that we file with the U.S. Securities and Exchange Commission. Any forward-looking statement in this release speaks only as of the date of this release. Inhibikase undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws. Contacts: Company Contact:Milton H. Werner, PhDPresident & CEO678-392-3419info@inhibikase.com Investor Relations:Alex LoboStern Investor Relations, Inc.alex.lobo@sternir.com Inhibikase Therapeutics, Inc. Consolidated Balance Sheets December 31,2023 December 31,2022 Assets ​ ​ Current assets: ​ ​ Cash and cash equivalents $9,165,179 $7,188,553 Marketable securities 4,086,873 15,861,620 Accounts receivable - 39,881 Prepaid research and development 219,817 1,117,616 Prepaid expenses and other current assets 739,179 163,452 Total current assets 14,211,048 24,371,122 Equipment and improvements, net 73,372 236,532 Right-of-use asset 222,227 328,643 Total assets $14,506,647 $24,936,297 Liabilities and stockholders’ equity ​ ​ Current liabilities: ​ ​ Accounts payable $646,767 $1,151,173 Lease obligation, current 150,095 145,836 Accrued expenses and other current liabilities 2,259,955 2,398,436 Insurance premium financing payable 381,784 — Total current liabilities 3,438,601 3,695,445 Lease obligations, net of current portion 90,124 205,451 Total liabilities 3,528,725 3,900,896 Commitments and contingencies (see Note 14) ​ ​ Stockholders’ equity: ​ ​ Preferred stock, $0.001 par value; 10,000,000 shares authorized at December 31, 2023 and 2022; 0 shares issued and outstanding at December 31, 2023 and 2022 — — Common stock, $0.001 par value; 100,000,000 shares authorized; 6,186,280 and 4,224,294 shares issued and outstanding at December 31, 2023 and 2022 6,186 4,224 Additional paid-in capital 77,871,584 68,798,301 Accumulated other comprehensive income 877 104,718 Accumulated deficit (66,900,725) (47,871,842)Total stockholders' equity 10,977,922 21,035,401 Total liabilities and stockholders’ equity $14,506,647 $24,936,297 See accompanying notes to consolidated financial statements. Inhibikase Therapeutics, Inc. Consolidated Statements of Operations and Comprehensive Loss Year ended December 31, 2023 2022 Revenue: Grant revenue $260,501 $123,440 Total revenue 260,501 123,440 Costs and expenses: Research and development 13,618,348 12,034,985 Selling, general and administrative 6,731,945 6,217,063 Total costs and expenses 20,350,293 18,252,048 Loss from operations (20,089,792) (18,128,608)Interest income 1,060,909 74,453 Net loss (19,028,883) (18,054,155)Other comprehensive income, net of tax: Unrealized gains (losses) on marketable securities (103,841) 104,718 Comprehensive loss $(19,132,724) $(17,949,437)Net loss per share – basic and diluted $(3.57) $(4.28)Weighted-average number of common shares – basic and diluted 5,333,096 4,223,099 See accompanying notes to consolidated financial statements.

CAPE CANAVERAL, Fla., March 27, 2024 (GLOBE NEWSWIRE) -- Vaxxinity, Inc. (Nasdaq: VAXX), a U.S. company pioneering the development of a new class of immunotherapeutic vaccines, today reported financial results for the fourth quarter and full year ended December 31, 2023, and provided a corporate update. “2024 will prove to be a critical year for Vaxxinity as we refocus our efforts on our neurodegeneration programs and move closer to obtaining our company’s first approval,” said Mei Mei Hu, CEO of Vaxxinity. “Just this month, we presented exploratory biomarker data from our Phase 1 trial of UB-312 in Parkinson’s patients: a first of its kind demonstrating target engagement of toxic alpha-synuclein in the CNS and a potential correlation with clinical efficacy. This represents a major step for our platform in neurodegeneration where the safe engagement of aberrant protein targets in the CNS remains critical, and new hope for the Parkinson’s community. We also seek to advance UB-311, our anti-Aβ Alzheimer’s candidate, as we resume dialogue with regulatory authorities and partners. Finally, we’re looking forward to the readout from the Phase 1 trial of VXX-401, our vaccine candidate for hypercholesterolemia, as well as the potential marketing authorization of UB-612, our heterologous booster vaccine candidate for COVID-19.” 2023 and Recent Clinical Pipeline Developments UB-312 in Parkinson’s disease (PD) and other synucleinopathies UB-312 targets toxic forms of aggregated α-synuclein (aSyn). Two exploratory CSF biomarkers show promise as measures of disease progression: aggregated aSyn, as measured by an aSyn Seed Amplification Assay developed in collaboration with Mayo Clinic, UTHealth Houston, and Amprion, with funding from The Michael J. Fox Foundation. phosphorylated aSyn (pS129-aSyn). PD patients with UB-312-induced antibodies in CSF had significantly less aSyn aggregation (p = 0.0183) and pS129-aSyn (p = 0.0351) as compared to placebo. PD patients with UB-312-induced antibodies in CSF showed significant improvement in the clinical MDS-UPDRS II activities of daily living scale as compared to placebo (p = 0.0062). Anti-aSyn antibody titer levels in CSF correlate with reduction in aggregated aSyn, which correlated with improvement in MDS-UPDRS II. In March 2024, JC Dodart, Chief Scientific Officer, presented these exploratory analyses at AD/PD 2024 in Lisbon, Portugal. VXX-401 in hypercholesterolemia VXX-401 targets proprotein convertase subtilisin/kexin type 9 (PCSK9) to reduce LDL cholesterol. All six cohorts of the Phase 1 trial of VXX-401 are fully enrolled. In February 2024, results from multiple preclinical studies of VXX-401 in non-human primates, demonstrating robust, sustained reduction in LDL-C, were published in the Journal of Lipid Research. The company anticipates topline Phase 1 data by mid-2024. UB-612 COVID-19 booster UB-612 employs a “multitope” approach to neutralizing the ancestral SARS-CoV-2 virus and its variants. In November 2023, Vaxxinity presented data from its head-to-head Phase 3 trial of UB-612 at Vaccines Summit in Boston, MA, and published a peer-reviewed article about UB-612 in Vaccine reporting antibody response against SARS-CoV-2 in cynomolgus macaques. 2023 and Recent Corporate Updates Academic Collaborations & State of Florida Grant. In January 2024 Vaxxinity announced a collaboration with the University of Central Florida to conduct research funded by the state of Florida to further the development of our active immunotherapies against myostatin and activin A to prevent and mitigate muscle and bone wasting, well-known health challenges related to long-term spaceflight. These targets share biological mechanisms implicated in obesity, diabetes, and highly prevalent age-related diseases. In the same month, Vaxxinity announced a collaboration with the University of Florida’s Center for Translational Research in Neurodegenerative Disease (CTRND) to support our development of vaccines for neurodegenerative diseases. Fourth Quarter and Year End 2023 Financial Results As of December 31, 2023, Vaxxinity had $30.4 million of highly liquid assets, including $4.9 million of cash and cash equivalents and $25.5 million of short-term investments, compared to $86.8 million as of December 31, 2022. Comparison of three months ended December 31, 2023 to three months ended December 31, 2022 Research and development expenses were $8.2 million and $13.1 million for the three months ended December 31, 2023 and 2022, respectively. The $4.9 million decrease in research and development expenses was primarily due to decreases in program-related costs of $0.6 million for our UB-313 migraine program, $0.4 million for our VXX-401 hypercholesterolemia program, and $0.4 million for our UB-312 Parkinsons program, as well decreases in personnel and consulting costs totaling $2.1 million. General and administrative expenses were $3.4 million and $7.7 million for the three months ended December 31, 2023, and 2022, respectively. The $4.3 million decrease was primarily due to a decrease in personnel costs of $1.7 million, consulting and professional services totaling $0.9 million, and travel expenses of $0.5 million. Net loss for the three months ended December 31, 2023, was $11.4 million or $0.09 per share compared to $20.5 million or $0.16 per share for the three months ended December 31, 2022. Comparison of the year ended December 31, 2023 to the year ended December 31, 2022 Research and development expenses were $35.9 million and $47.6 million for the years ended December 31, 2023 and 2022, respectively. The $11.7 million decrease in research and development expenses was primarily due to decreases in program-related costs of $4.3 million for our UB-612 Covid-19 program and $1.0 million for our UB-312 Parkinson’s Disease program, as well decreases in personnel costs of $4.2 million and consulting costs of $1.8 million. General and administrative expenses were $22.4 million and $28.4 million for the years ended December 31, 2023, and 2022, respectively. The $6.0 million decrease was primarily due to a decrease in personnel costs of $2.0 million, D&O insurance premiums of $1.8 million, and consulting and professional services costs of $1.2 million. Net loss for the year ended December 31, 2023, was $56.9 million or $0.45 per share compared to $75.2 million or $0.60 per share for the year ended December 31, 2022. VAXXINITY, INC. Statement of Operations (In thousands, except number of shares and per share amounts) Three Months Ended Years Ended December 31, December 31, 2023 2022 2023 2022 Operating expenses: Research and development 8,220 13,018 35,899 47,627 General and administrative 3,430 7,806 22,386 28,352 Total operating expenses 11,650 20,824 58,285 75,979 Loss from operations (11,650 ) (20,824 ) (58,285 ) (75,979 ) Other (income) expense: Interest and other expense 182 250 696 514 Interest and other income (433 ) (634 ) (2,090 ) (1,259 ) (Gain) loss on foreign currency transactions, net (7 ) 16 43 (12 ) Other (income) (258 ) (368 ) (1,351 ) (757 ) Net loss $ (11,392 ) $ (20,456 ) $ (56,934 ) $ (75,222 ) Net loss per share, basic and diluted $ (0.09 ) $ (0.16 ) $ (0.45 ) $ (0.60 ) Weighted average common shares outstanding, basic and diluted 126,736,784 126,056,241 126,508,917 125,939,050 VAXXINITY, INC. Selected Balance Sheet Data (in Thousands) December 31, December 31, 2023 2022 Cash and cash equivalents $ 4,931 $ 33,475 Short term investments 25,464 53,352 Total assets 44,311 106,399 Total liabilities 30,902 44,222 Total stockholder's equity 13,409 62,177 About Vaxxinity Vaxxinity, Inc. is a purpose-driven biotechnology company committed to democratizing healthcare across the globe. The company is pioneering a new class of synthetic, peptide-based active immunotherapy medicines aimed at disrupting the existing treatment paradigm for chronic disease, increasingly dominated by monoclonal antibodies, which suffer from prohibitive costs and cumbersome administration. The company’s proprietary technology platform has enabled the innovation of novel pipeline candidates designed to bring the efficiency of vaccines to the treatment of chronic diseases, including Alzheimer’s, Parkinson’s, migraine, and hypercholesterolemia. The technology is also implemented as part of a COVID-19 vaccine program. Vaxxinity has optimized its pipeline to achieve a potentially historic, global impact on human health. For more information about Vaxxinity, Inc., visit and follow us on social media @vaxxinity. Forward-looking Statements This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The use of certain words, including "believe," "may," "continue," "advancing," "will" and similar expressions, are intended to identify forward-looking statements. Forward-looking statements include statements, other than statements of historical fact, regarding, among other things: the plans for, or progress, scope, initiation, duration, enrollment, results or timing for availability of results of, development of any of Vaxxinity’s product candidates or programs; the target indication(s) for development or approval, the size, design, population, location, conduct, cost, objective, enrollment, duration or endpoints of any clinical trial, or the timing for initiation or completion of or availability or reporting of results from any clinical trial; the potential future regulatory authorization or approval and commercialization of Vaxxinity’s product candidates; the potential benefits or competitive position of any Vaxxinity product candidate or program or the commercial opportunity in any target indication; and Vaxxinity’s plans, expectations or future operations, financial position, revenues, costs or expenses. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of Vaxxinity’s management about the development of a new class of immunotherapeutic vaccines and the innovation and efficacy of Vaxxinity’s product candidates. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements, including, but not limited to: whether UB-311, UB-312, UB-313, VXX-401, UB-612 or any other current or future product candidate of Vaxxinity will be approved or authorized by any regulatory agency for the indications that Vaxxinity targets; any potential negative impacts of the COVID-19 pandemic, including on manufacturing, supply, conduct or initiation of clinical trials, or other aspects of Vaxxinity’s business; Vaxxinity’s product candidates may not be successful or clinical development may take longer and be more costly than anticipated; product candidates that appeared promising in earlier research and clinical trials may not demonstrate safety or efficacy in larger-scale or later clinical trials or in clinical trials for other indications; the timing for initiation or completion of, or for availability of data from, clinical trials for UB-311, UB-312, UB-313, VXX-401 or UB-612, and the outcomes of such trials; Vaxxinity’s reliance on collaborative partners and other third parties for development of its product candidates; Vaxxinity’s ability to obtain coverage, pricing or reimbursement for any approved products and acceptance from patients and physicians for any approved indications; delays or other challenges in the recruitment of patients for, or the conduct of, Vaxxinity’s clinical trials; challenges associated with supply and manufacturing activities; and Vaxxinity’s accounting policies. These and other important factors to be considered in connection with forward-looking statements are described in the "Risk Factors" section of Vaxxinity’s Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission on March 27, 2024. The forward-looking statements are made as of this date and Vaxxinity does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. Investor Contact Mark Joinnides ir@vaxxinity.com Press Contact Ali Nagy / McKenna Miller anagy@kcsa.com / mmiller@kcsa.com

MELBOURNE, Australia and SAN FRANCISCO, March 27, 2024 (GLOBE NEWSWIRE) -- Alterity Therapeutics Limited (ASX: ATH, NASDAQ: ATHE) (“Alterity” or “the Company”), a biotechnology company dedicated to developing disease modifying treatments for neurodegenerative diseases, today announced that it has received a A$3.9 million cash refund from the Australian Taxation Office under the Australian Government’s Research and Development Tax Incentive (R&DTI) Scheme. The cash refund relates to the cost of eligible research and development activities conducted during the financial year ended 30 June 2023, and represents the amount disclosed in the company’s audited financial statements. These funds will be used to further Alterity’s Phase 2 clinical trials in MSA, ATH434-201 and ATH434-202, along with planning for a potential Phase 3 clinical trial in MSA, continuing discovery and research efforts in neurodegenerative diseases, including Parkinson’s Disease, and general working capital. About ATH434Alterity’s lead candidate, ATH434, is an oral agent designed to inhibit the aggregation of pathological proteins implicated in neurodegeneration. ATH434 has been shown preclinically to reduce α-synuclein pathology and preserve neuronal function by restoring normal iron balance in the brain. As an iron chaperone, it has excellent potential to treat Parkinson’s disease as well as various Parkinsonian disorders such as Multiple System Atrophy (MSA). ATH434 is currently being studied in two clinical trials: Study ATH434-201 is a randomized, double-blind, placebo-controlled Phase 2 clinical trial in patients with early-stage MSA and Study ATH434-202 is an open-label Phase 2 Biomarker trial in patients with more advanced MSA. ATH434 has been granted Orphan drug designation for the treatment of MSA by the U.S. FDA and the European Commission. About Alterity Therapeutics LimitedAlterity Therapeutics is a clinical stage biotechnology company dedicated to creating an alternate future for people living with neurodegenerative diseases. The Company’s lead asset, ATH434, has the potential to treat various Parkinsonian disorders and is currently being evaluated in two Phase 2 clinical trials in Multiple System Atrophy. Alterity also has a broad drug discovery platform generating patentable chemical compounds to treat the underlying pathology of neurological diseases. The Company is based in Melbourne, Australia, and San Francisco, California, USA. For further information please visit the Company’s web site at www.alteritytherapeutics.com. Authorisation & Additional informationThis announcement was authorized by David Stamler, CEO of Alterity Therapeutics Limited. Investor and Media Contacts: AustraliaHannah Howlettwe-aualteritytherapeutics@we-worldwide.com+61 450 648 064 U.S.Remy Bernarda remy.bernarda@iradvisory.com+1 (415) 203-6386