预约演示
更新于：2026-07-11
Citric Acid/Magnesium Oxide/Sodium Picosulfate
匹可硫酸钠/氧化镁/柠檬酸
更新于：2026-07-11
概要
基本信息
原研机构 |
权益机构- |
最高研发阶段批准上市 |
首次获批日期 美国 (2012-07-16), |
最高研发阶段(中国)临床3期 |
特殊审评- |
登录后查看时间轴
结构/序列
分子式MgO |
InChIKeyCPLXHLVBOLITMK-UHFFFAOYSA-N |
CAS号1309-48-4 |
查看全部结构式(3)
关联
30
项与 匹可硫酸钠/氧化镁/柠檬酸 相关的临床试验NCT07696793
Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy: a Randomized Parallel Comparative Trial CLEAN+
JPRN-jRCTs051250181
Pilot Study on the Effect of PicoPrep as a Bowel Preparation on Visualization Quality in Small Bowel Capsule Endoscopy.
NCT06580366
Sennosid A+B Versus Sodium Picosulfate/Magnesium Oxide/Citric Acid for Bowel Preparation; A Prospective Randomized Observer-Blinded Study
100 项与 匹可硫酸钠/氧化镁/柠檬酸 相关的临床结果
登录后查看更多信息
100 项与 匹可硫酸钠/氧化镁/柠檬酸 相关的转化医学
登录后查看更多信息
100 项与 匹可硫酸钠/氧化镁/柠檬酸 相关的专利（医药）
登录后查看更多信息
25
项与 匹可硫酸钠/氧化镁/柠檬酸 相关的文献（医药）2020-01-01International journal of preventive medicine
Effects of probiotic soy milk fermented by lactobacillus plantarum A7 (KC 355240) added with Cuminum Cyminum essential oil on fasting blood glucose levels, serum lipid profile and body weight in diabetic Wistar rats
Article
作者: Torki-Baghbadorani, Sahar ; Azadbakht, Leila ; Ghiasvand, Reza ; Babashahi, Mina ; Mirlohi, Maryam ; Mosharaf, Laleh
BACKGROUND:
There is some separate evidence that probiotic soy milk and Cuminum cyminum (C. cyminum) have positive effects on the prevention and reduction of diabetic complications. While the impact of probiotic soymilk mixed with herbal essential oils has not been investigated so far, the objective of this study is to examine the effects of probiotic soy milk using Lactobacillus plantarum A7 (KC 355240) added with essential oil of C. cyminum on diabetic rats.
METHODS:
50 streptozotocin-nicotinamide (STZ-NA) induced diabetic Wistar rats were divided into five groups: Control group (C group), soy milk group (SM group), probiotic soy milk group (PSM group), soy milk containing essential oil of C. cyminum group (SMC group) and probiotic soy milk containing essential oil of C. cyminum group (PSMC group). The animals consumed these products (1 ml/day) for 30 days. The fasting blood glucose (FBS), the serum lipid levels, and body weight variation were analyzed in 10-day intervals.
RESULTS:
FBS, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) decreased significantly, whereas high-density lipoprotein cholesterol (HDL-C) increased in the PSMC group compared with that of other groups (P < 0.05). This product also led to weight gain (P < 0.05).
CONCLUSIONS:
A mixture of probiotic soy milk and herbal essential oil consumption could impose a positive effect on reducing FBS as well as serum lipid profile in STZ- NA diabetes-induced rat. Also, it results in an increase in their weight gain.
2019-02-01The American journal of gastroenterology1区 · 医学
Comparing the Real-World Effectiveness of Competing Colonoscopy Preparations: Results of a Prospective Trial
1区 · 医学
Article
作者: Lew, Daniel ; Hsu, Kevin ; Almario, Christopher V. ; Fuller, Garth ; Gu, Phillip ; Mirakhor, Ebrahim ; Vipani, Aarshi ; Oh, Sun Jung ; Bullen, Tia ; Ko, Jeffrey ; Pattisapu, Varun ; Spiegel, Brennan M.R.
OBJECTIVES::
National societies provide little guidance regarding which colonoscopy bowel preps are best tolerated and most effective; this reflects a lack of comparative effectiveness studies that directly evaluate the available preps in a “real-world” setting. To address this gap, we conducted a prospective, commercially unfunded comparative effectiveness study of currently available bowel preps and measured their impact on bowel cleansing.
METHODS::
We included patients aged ≥18 years, who presented for an outpatient colonoscopy at a large medical center serving more than 70 academic and community-based endoscopists who are free to prescribe the bowel prep of their choice. The primary outcome was bowel cleansing quality as measured by the Boston Bowel Preparation Scale. We performed regression models with random effects on the outcomes to adjust for confounding.
RESULTS::
Approximately 4,339 colonoscopies were performed by 75 endoscopists. Magnesium citrate, MiraLAX with Gatorade, MoviPrep, OsmoPrep, Prepopik/Clenpiq, and Suprep all had significantly higher prep tolerability compared with GoLYTELY (all P < 0.05). For bowel cleansing, Suprep (7.28 ± 1.66; P < 0.001), MoviPrep (7.11 ± 1.62; P = 0.004), and MiraLAX with Gatorade (7.09 ± 1.64; P < 0.001) had higher total Boston Bowel Preparation Scale scores compared with GoLYTELY (6.67 ± 1.87); there were no significant differences among the remaining preps. Split-prep dosing was associated with better cleansing; however, men, opioid and tricyclic antidepressent users, and patients with diabetes and cirrhosis had worse cleansing (all P < 0.05).
CONCLUSIONS::
In this prospective, real-world comparative effectiveness study of available bowel preps, we found that MiraLAX with Gatorade, MoviPrep, and Suprep were prospectively associated with superior tolerability and bowel cleansing.
2018-10-01Journal of colloid and interface science2区 · 化学
Preparation and application of a molecular capture for safety detection of cosmetics based on surface imprinting and multi-walled carbon nanotubes
2区 · 化学
Article
作者: Tan, Xuecai ; Li, Xiaoyan ; Wang, Fang ; Liu, Li ; Wu, Zongyuan ; Liu, Min ; Zhu, Chen ; Lei, Fuhou ; Li, Junjie
A novel composite material for prednisone molecular capture (PS-MC) was prepared by surface imprinting technique in combination with a polyethylene filter plate coated with multi-walled carbon nanotubes for the first time. PS-MC was achieved by using prednisone as the template molecule, 3-aminopropyltriethoxysilane as the monomer, and tetraethoxysilane as the cross-linker. The structure, morphology, and thermal stability of the prepared PS-MC were studied by fourier-transform infrared spectrometry, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and thermogravimetric analysis. PS-MC was assessed by re-binding experiments such as adsorption kinetics, adsorption isotherms, molecular identification, and applied to the separation and enrichment of prednisone in cosmetics. The results indicated that PS-MC has rapid binding kinetic, high adsorption capacity, and favorable reusability. The imprinted materials were coupled with HPLC to selectively separation, purification, and detection of prednisone from spiked cosmetic samples. The recoveries of spiked cosmetic samples were in the range of 83.0-106.0%, with relative standard deviations of less than 2.10%, and the limit of detection of 5 ng/mL (S/N = 3).
21
项与 匹可硫酸钠/氧化镁/柠檬酸 相关的新闻（医药）2026-04-10
100 项与 匹可硫酸钠/氧化镁/柠檬酸 相关的药物交易
登录后查看更多信息
外链
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
研发状态
10 条最早获批的记录, 后查看更多信息
登录
| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 结肠疾病 | 日本 | 2016-07-04 | |
| 肠道准备 | 美国 | 2012-07-16 |
登录后查看更多信息
临床结果
临床结果
适应症
分期
评价
查看全部结果
临床4期 | 705 | Sennoside A + B oral solution | 膚鏇夢遞積鹽遞選醖積(鏇齋壓艱鹹鬱顧廠窪壓) = 範襯蓋醖顧鏇遞選壓製 膚蓋製糧構壓獵網簾願 (獵製壓艱艱齋膚鹽顧餘 ) 更多 | 积极 | 2026-05-14 | ||
Picosulfate/Magnesium Oxide/Citric Acid (PM/Ca) | 膚鏇夢遞積鹽遞選醖積(鏇齋壓艱鹹鬱顧廠窪壓) = 膚衊選夢築醖餘壓餘艱 膚蓋製糧構壓獵網簾願 (獵製壓艱艱齋膚鹽顧餘 ) 更多 | ||||||
临床4期 | - | 14 | (Group A) | 廠艱遞積範觸選範製鬱 = 廠壓鹹製艱醖淵選鹽鹹 糧餘齋構艱糧醖鹹膚艱 (鹽範遞艱範選積鏇廠蓋, 艱醖蓋選糧鏇廠觸餘鬱 ~ 壓夢簾獵簾鑰窪蓋鬱構) 更多 | - | 2021-03-04 | |
(Group B) | 廠艱遞積範觸選範製鬱 = 蓋窪鏇鑰醖壓醖淵餘鹽 糧餘齋構艱糧醖鹹膚艱 (鹽範遞艱範選積鏇廠蓋, 艱鑰憲艱製醖繭鑰築獵 ~ 艱繭齋齋糧壓製選壓構) 更多 | ||||||
N/A | - | 32 | (Low Volume Prep (Prepopik)) | 壓蓋顧獵積廠憲製夢築(憲繭蓋衊願選艱壓顧衊) = 繭艱襯艱鹹繭顧網繭製 製選選範築選襯齋鬱願 (蓋鬱鬱齋觸窪壓觸鹹範, 1.62) 更多 | - | 2020-07-17 | |
(Moderate Volume Prep (Moviprep)) | 壓蓋顧獵積廠憲製夢築(憲繭蓋衊願選艱壓顧衊) = 窪憲鬱築觸簾顧構簾膚 製選選範築選襯齋鬱願 (蓋鬱鬱齋觸窪壓觸鹹範, 1.55) 更多 | ||||||
临床1/2期 | - | 78 | (Prepopik® ½ Sachet x 2 (9-12 Years)) | 製壓獵鏇蓋憲壓觸獵夢 = 範願衊鏇廠廠壓鏇鬱膚 積範鹹餘壓網獵鏇憲壓 (積膚餘鹽鏇鏇廠廠觸膚, 餘顧簾觸網齋憲網鹽膚 ~ 築壓艱築鏇壓積蓋簾襯) 更多 | - | 2018-04-23 | |
(Prepopik® 1 Sachet x 2 (9-12 Years)) | 製壓獵鏇蓋憲壓觸獵夢 = 鹽衊廠選夢範構艱繭鑰 積範鹹餘壓網獵鏇憲壓 (積膚餘鹽鏇鏇廠廠觸膚, 遞鹽築簾鬱積鹽構壓艱 ~ 鹹鏇鹹願夢鬱鬱獵艱廠) 更多 | ||||||
临床3期 | 637 | (Treatment Arm [1]: FE 999169) | 網選築觸淵簾壓襯願衊 = 窪齋網繭願鏇膚簾壓觸 鹽構簾顧選壓餘製觸顧 (鹽築鹽鏇艱範憲製襯鏇, 廠願範鹽壓蓋鏇壓獵壓 ~ 襯憲鹽憲淵壓艱範選醖) 更多 | - | 2017-07-17 | ||
(Treatment Arm [2]: FE 999169) | 網選築觸淵簾壓襯願衊 = 製醖鑰淵糧膚願窪鹽艱 鹽構簾顧選壓餘製觸顧 (鹽築鹽鏇艱範憲製襯鏇, 膚鹹蓋壓鬱壓顧蓋製憲 ~ 鏇醖膚積鹽襯鏇範製餘) 更多 | ||||||
临床3期 | 204 | (PICOPREP Day-before Dosing Schedule) | 膚膚遞窪艱淵鬱構鹽獵(遞窪艱範醖鹽淵鹽範網) = 範築選構範壓範鏇網襯 夢艱範襯簾鬱積鑰選壓 (獵遞廠簾蓋遞鑰淵糧壓, 3.54) 更多 | - | 2016-06-23 | ||
(PICOPREP Tailored Dosing Schedule) | 膚膚遞窪艱淵鬱構鹽獵(遞窪艱範醖鹽淵鹽範網) = 艱鹽襯鹹餘鬱淵顧構繭 夢艱範襯簾鬱積鑰選壓 (獵遞廠簾蓋遞鑰淵糧壓, 3.75) 更多 | ||||||
临床3期 | - | P/MC Split-dose | 衊製齋鑰選網餘獵壓鹽(鑰鏇糧簾鏇壓願顧鬱願) = Both dosing regimens of P/MC were equally effective at bowel cleansing in all pts, regardless of age 鹽蓋鹹願鹹鑰壓繭廠觸 (鬱獵齋鑰淵廠鏇遞築選 ) 更多 | 积极 | 2014-02-01 | ||
P/MC Day Before | |||||||
临床3期 | - | 300 | 壓繭繭積襯鹹繭餘夢鬱(鏇鹽淵襯築簾積遞廠鑰) = 遞廠憲獵鏇鹹醖憲襯築 餘繭鏇顧廠鏇襯構鑰觸 (範餘範齋糧淵網築鹽淵, 2.48) 更多 | - | 2013-01-28 | ||
临床3期 | - | 608 | (PICOPREP) | 夢蓋顧醖蓋顧淵餘蓋積 = 鬱襯網築遞範遞遞壓淵 顧艱築淵觸鑰網鏇鑰觸 (膚網糧壓獵鏇選鏇築遞, 鏇鏇鑰襯鑰壓繭遞鏇衊 ~ 廠顧觸襯齋糧蓋簾壓製) 更多 | - | 2012-09-11 | |
(HalfLytely) | 夢蓋顧醖蓋顧淵餘蓋積 = 網願簾獵廠鬱醖夢衊壓 顧艱築淵觸鑰網鏇鑰觸 (膚網糧壓獵鏇選鏇築遞, 膚鹽壓齋簾廠醖壓積遞 ~ 鬱窪獵積鹹鬱艱顧願衊) 更多 | ||||||
临床3期 | - | 603 | (PicoPrep) | 夢襯範顧醖糧構積遞範 = 鏇鹹壓積鏇遞製廠鏇鹽 鹹糧繭鑰襯衊獵壓觸襯 (築蓋餘廠遞鹹構簾觸衊, 壓淵繭鬱積憲製齋觸鬱 ~ 淵窪遞鑰範醖繭鹹鏇鹹) 更多 | - | 2012-09-11 | |
(HalfLytely) | 夢襯範顧醖糧構積遞範 = 顧簾糧齋製襯艱構膚艱 鹹糧繭鑰襯衊獵壓觸襯 (築蓋餘廠遞鹹構簾觸衊, 壓壓構廠鹹顧網衊壓鹽 ~ 醖淵積構齋繭蓋蓋衊襯) 更多 |
登录后查看更多信息
转化医学
使用我们的转化医学数据加速您的研究。
登录
或
药物交易
使用我们的药物交易数据加速您的研究。
登录
或
核心专利
使用我们的核心专利数据促进您的研究。
登录
或
临床分析
紧跟全球注册中心的最新临床试验。
登录
或
批准
利用最新的监管批准信息加速您的研究。
登录
或
特殊审评
只需点击几下即可了解关键药物信息。
登录
或
生物医药百科问答
全新生物医药AI Agent 覆盖科研全链路，让突破性发现快人一步
立即开始免费试用!
智慧芽新药情报库是智慧芽专为生命科学人士构建的基于AI的创新药情报平台，助您全方位提升您的研发与决策效率。
立即开始数据试用!
智慧芽新药库数据也通过智慧芽数据服务平台，以API或者数据包形式对外开放，助您更加充分利用智慧芽新药情报信息。
生物序列数据库
生物药研发创新
免费使用
化学结构数据库
小分子化药研发创新
免费使用