聚维酮碘(Povidone-Iodine) - 在研适应症：压疮，细菌感染和真菌病，烧伤感染_专利_临床

概要

基本信息

药物类型

小分子化药

别名

Povidone Iodine、Povidone-iodine (JP17/USP)、原位凝胶缓释滴眼液

+ [12]

靶点-

作用机制-

治疗领域

感染心血管疾病消化系统疾病+ [7]

在研适应症

压疮细菌感染和真菌病烧伤感染+ [12]

非在研适应症

急性腺病毒滤泡性结膜炎新型冠状病毒感染牙菌斑

原研机构

Alcon Pharmaceuticals Ltd.

在研机构

亚宝药业四川制药有限公司

IVIEW Therapeutics, Inc.初创企业Bio-Concept Laboratories, Inc.

+ [9]

非在研机构

Colgate-Palmolive Co.Clinipad Corp.Kendall Corp.

最高研发阶段批准上市

首次获批日期

日本 (1965-11-01),

消毒剂

最高研发阶段(中国)批准上市

特殊审评-

登录后查看时间轴

结构

分子式C6H9I2NO

InChIKeyCPKVUHPKYQGHMW-UHFFFAOYSA-N

CAS号25655-41-8

关联

269

项与聚维酮碘相关的临床试验

NCT06667089 / RecruitingN/AIIT

Comparison of Povidone-Iodine and Chlorhexidine in the Management of Iatrogenic Wounds in Surgical Patients

This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients. Both antiseptics are commonly used to prevent postoperative infections, but they differ in mechanism, efficacy, and safety profiles. Povidone-iodine releases iodine, which acts broadly against bacteria, viruses, and fungi, while chlorhexidine disrupts cell membranes, providing rapid bactericidal action. Studies suggest that chlorhexidine may offer longer-lasting antibacterial effects, but povidone-iodine has a wider antimicrobial range. Optimal choice depends on patient needs, wound type, and potential for adverse reactions, emphasizing the need for tailored antiseptic strategies in wound care.

开始日期2025-01-07

申办/合作机构-

CTRI/2024/07/070366 / Not yet recruitingN/AIIT

Efficacy of Superoxidised solution and Povidone iodine solution with periodontal dressing in gingival depigmentation A split mouth randomized controlled trial - NIL

开始日期2025-01-03

申办/合作机构-

NCT06463678 / Not yet recruiting临床2期

A Phase II, Multi-center, Randomized, Masked, Parallel-Control Study to Evaluate the Clinical Efficacy and Safety of IVIEW-1201 (1.0% PVP-Iodine) Gel Forming Ophthalmic Solution in the Treatment of Fungal Keratitis

A Phase II, Multi-center, Randomized, Masked, Parallel-Control Study to Evaluate the Clinical Efficacy and Safety of IVIEW-1201 (1.0% PVP-Iodine) Gel Forming Ophthalmic Solution in the Treatment of Fungal Keratitis.

开始日期2024-12-01

申办/合作机构

IVIEW Therapeutics, Inc.初创企业

100 项与聚维酮碘相关的临床结果

登录后查看更多信息

100 项与聚维酮碘相关的转化医学

登录后查看更多信息

100 项与聚维酮碘相关的专利（医药）

登录后查看更多信息

4,733

项与聚维酮碘相关的文献（医药）

2025-04-01·Journal of Orthopaedics

Analysis of adolescent idiopathic scoliosis population for Surgical Site Infection Risk Factors

Article

作者: Thometz, John G ; Liu, Xue-Cheng ; Fletcher, Jesse ; Thometz, John G.

ObjectiveThe incidence of surgical site infection (SSI) in adolescent idiopathic scoliosis (AIS) patients undergoing surgical correction varies but is commonly reported between 0.5 and 6.7 %. The identification of modifiable risk factors is crucial to preventing these infections in the AIS population. Some potential modifiable risk factors include the use of stainless-steel implants, a larger volume of instrumentation and an increased volume of blood products transfused. However, evidence in support of these factors and others representing true risk for the development of SSI is limited and often varies. We aimed to determine the incidence of SSI in AIS undergoing primary scoliosis fusion at our hospital, and explore demographic and clinical variables in the development of SSI in AIS.MethodsThis was a case control retrospective study. Patients aged 10-19 year-old that underwent posterior spinal fusion for initial correction of AIS at our hospital between the years 2012-2020 were eligible. Patients with any previous spine surgery or spine fracture were excluded. A descriptive analysis was then performed on the data.ResultsOf the 334 patients on which data was collected, one SSI was identified resulting in an incidence of infection of 0.3 %. The largest ethnicity represented was Caucasian with 254 patients. The average age was 14.3 years with averaged follow-up of 6.6 years. The majority of patients (252) received implants composed of titanium and cobalt chrome. The average operation duration was 5 h and 7.7 min, and the average hospital stay was 4.2 days. The average amount of blood loss was 553 ml. Chlorhexidine wipes or some other antimicrobial preparation was used on 197 patients and betadine solution was used on 321.185 patients were recorded to have received either antibiotic-loaded allograft or antibiotic powder and 326 patients were recorded to have received intraoperative antibiotics.ConclusionsThe long term clinical follow up of our study and low incidence of infection provide additional evidence for the benefit of antimicrobial techniques and risk factor mitigation previously suggested in the literature for the prevention of SSI in AIS.Level of evidenceLevel III.

2024-12-01·Veterinary Parasitology

Evaluation of the efficacy of disinfectants and disinfection methods against Ascaris suum eggs

Article

作者: Tian, Lihong ; Yang, Yuling ; Lu, Maolin ; Lu, Yaxian ; Liu, Tianlu ; Zhou, Mengchao ; Yu, Hongyan ; Tian, Hang ; Cui, Zhiying ; Zhang, Ruisi ; Han, Lei ; Hou, Zhijun

Ascaris is highly adaptable, allowing its offspring to thrive in various conditions and posing significant health risks widely among animal populations. Most studies regarding the efficacy of disinfectants against Ascaris eggs in animal houses have been limited and lack a systematic and comprehensive evaluation. Currently, Ascaris suum is one of the most extensively studied helminths in the context of parasitology. Here, 8 disinfectants, UV radiation and quicklime were used to treat A. suum eggs, which were subsequently incubated at a room temperature of 22-25ºC for 15 days. The inactivation rate of A. suum eggs (expressed as a percentage) was measured to assess the efficacy of disinfectants, UV radiation, and quicklime in inactivating A. suum eggs. The results indicated that 1 %-10 % povidone iodine, 5 %-25 % ammonia solution, 0.5-2 % chlorine dioxide, 75 % ethanol and formalin in long-term (15 days), as well as the 5 % and 10 % povidone iodine, 25 % ammonia solution and UV irradiation in short-term (30-120 min) completely inhibited the normal development of A. suum eggs up to L2 stage. In conclusion, 75 % ethanol, povidone iodine, chlorine dioxide, ammonia solution, formalin, and UV irradiation are effective in inactivating A. suum eggs for dual disinfection of parasites and microorganisms. Among them, povidone iodine and UV irradiation are relatively efficient and environmentally friendly disinfection methods, and chlorine dioxide, a relatively harmless and broad-spectrum disinfectant, is an alternative choice for A. suum eggs elimination.

2024-12-01·Journal of Orthopaedic Research

Effects of antiseptic irrigation solutions on osseointegration in a cementless tibial implantation mouse model

Article

作者: Döring, Kevin ; Thomson, Andrew ; Bostrom, Mathias P. G. ; Li, Qingdian ; Hammad, Mohammed ; Ivashkiv, Lionel B. ; Oktarina, Anastasia ; Yang, Xu ; Suhardi, Vincentius J. ; Augustin, Edouard J. ; Carli, Alberto V.

AbstractDespite the success of standard antiseptic irrigation solutions in reducing periprosthetic joint infection (PJI) rates, there is still a need for more effective solutions. Synergistic use of povidone‐iodine (PI) and hydrogen peroxide (H2O2) has shown promising results; however, the optimal solution concentration balancing bactericidal activity and osseointegration remains unknown. This study aims to evaluate the impact of these antiseptic irrigation solutions on osseointegration and the bone–implant interface strength in vivo. Forty C57BL/6 mice underwent bilateral tibial implantation surgery and were randomly allocated into three groups receiving 0.3% PI, 10% PI mixed with 3% H2O2, or saline as irrigation solutions intraoperatively. Assessments were performed on postoperative Days 1 and 28, including plain radiographs, microcomputed tomography (microCT) evaluation, histological analysis, immunohistochemistry, and biomechanical pull‐out testing. No wound complications were observed. MicroCT scans revealed no differences in peri‐implant trabecular bone parameters. Biomechanical pull‐out testing showed no differences in the bone–implant interface strength across groups. Histological analysis indicated no differences in bone and bone marrow percentage areas among treatment groups. Immunohistochemical analysis demonstrated no differences among groups in peri‐implant osteocalcin, osterix, or endomucin‐positive cells. In conclusion, using either antiseptic irrigation solution showed no differences in osseointegration parameters compared to the control group, demonstrating safety and the absence of toxicity.Clinical RelevanceDilute 0.3% povidone‐iodine and a 1:1 combination of 10% povidone‐iodine mixed with 3% hydrogen peroxide can be safely used during primary and revision total joint arthroplasty without compromising osseointegration or causing wound complications.

32

项与聚维酮碘相关的新闻（医药）

2024-09-23

·echemi

The uses of 10 povidone iodine solution

10 povidone iodine solution in this article refers to 10% povidone iodine solution, which means that this solution contains 10% povidone iodine (equivalent to 1% titratable iodine) and is a disinfectant. What are the main uses of 10 povidone iodine solution? About povidone iodine Povidone iodine is a loose complex formed by combining elemental iodine and a polymer carrier, with povidone acting as a carrier and solubilizer. It is a yellow-brown to brown-red amorphous powder at room temperature. It has a slight odor and is easily soluble in water or ethanol. The aqueous solution is acidic and insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride. Povidone iodine solution does not have the disadvantages of iodine tincture, is lightly colored, easy to wash off, has little irritation to the mucous membrane, does not require ethanol deiodination, has no corrosive effect, and has low toxicity. 10 povidone iodine solution can effectively kill Newcastle disease, bursal disease, avian influenza, mycoplasma, Escherichia coli, salmonella, influenza, blue ear disease, etc. It can also kill parasite eggs of livestock and poultry, and inhibit the breeding of insects such as mosquitoes and flies. It can also be used in fruit trees, crops, fish and shrimp farming. 10 povidone iodine solution is an external disinfectant used for cuts, abrasions, burns and minor skin wounds. Its mechanism of action is that after this product contacts the wound or the affected area, it can depolymerize and release the iodine contained to exert a bactericidal effect. It has the characteristics of low irritation to tissues and is suitable for skin and mucous membrane infections. It is usually used for purulent dermatitis, fungal skin infection, and small-area mild burns and scalds. It is also used to disinfect small-area skin and mucosal wounds. It is also a medical disinfectant used for skin preparation before surgery, or a disinfectant and cleanser for skin preparation before injection. 10 povidone iodine solution is a solution mainly used for skin wound disinfection. It does not need to be diluted when used. The disinfectant is applied directly to the damaged skin. It should be applied within 3-5cm around the lesion and applied twice a day. If necessary, the wound can be covered with sterile gauze to avoid infection. In summary, 10 povidone iodine solution is the most common topical disinfectant. When you need to treat the wound yourself after an injury to the outside of the body, 10 povidone iodine solution is a good choice.

2024-09-23

·echemi

Povidone iodine solution how to use | Detailed explanation

Povidone iodine, also known as iodopovidone, excellent-iodine, and Puweilong iodine, is a broad-spectrum antibacterial agent. Povidone iodine is widely used in medicine for surgical scrubbing, skin cleaning before and after surgery, prevention and treatment of infected wounds, ulcers, cuts, burns, bedsores and congestion ulcers, gynecological vaginitis, candida, trichomonas or mixed infections. The following is a brief introduction to povidone iodine solution how to use. Povidone iodine solution how to use? Currently, there are many preparations of different dosage forms and concentrations on the market. When using, pay attention to the use of each preparation: 1. 10% povidone iodine solution is a solution used for skin wound disinfection. It does not need to be diluted when used. Apply the disinfectant directly to the damaged skin. It should be applied within 3-5cm around the lesion and applied twice a day. If necessary, the wound can be covered with sterile gauze to avoid infection. 2. 1% povidone iodine solution is used for gargling and mouthwashing. It is suitable for oral bacterial infections, pharyngitis, tonsillitis and other conditions. When using, the solution can be used to gargle directly without dilution or dilute with warm water. Each dosage is about 10ml, gargle for 30 seconds, do not swallow, and use 2-4 times a day. Note that it should not be used for more than 14 days and is only limited to adults and children over 6 years old. 3. For dry powder spray 2.5%, shake the bottle before use, spray the medicine on the affected area 15-20cm away from the affected area until the foam covers the wound. If necessary, cover the wound with sterile gauze. Be careful not to spray into the mucosal cavity. It is limited to skin lesions. It is only for adults and children over 2 years old. Pregnant and lactating women should use it with caution. 4. For povidone iodine solution10% ointment, this dosage form is an external agent, apply it to the wound, and then cover it with sterile gauze. 5. Povidone iodine vaginal douche 10% is used to douche the vulva and assist in the treatment of gynecological inflammatory diseases, excessive leucorrhea, vaginitis, and cervicitis. Dilute about 10 ml of the solution with 1 liter of clean water and soak the private parts. After the symptoms disappear, stop douche and do not use it for a long time. In addition to understanding povidone iodine solution how to use, we should also pay attention to the fact that it may bring some side effects, including skin irritation. If applied to large wounds, people with poor renal function may cause hypernatremia and metabolic acidosis. It is not recommended for people who are less than 32 weeks pregnant or taking lithium salts. People with thyroid problems are advised not to use it frequently. In short, povidone iodine solution how to use is something you need to fully understand before treating the disease. Although there are few side effects, people need to strictly follow the drug instructions and doctor's advice when using povidone iodine.

2024-09-20

·echemi

Povidone iodine solution first aid antiseptic: how does it work?

Povidone iodine, also known as iodopovidone, excellent-iodine, and Puweilong iodine, is a broad-spectrum antibacterial agent. Povidone iodine solution first aid antiseptic is a type of iodine tincture, used for skin disinfection and sterilization before and after surgery, prevention and treatment of local wound infections, and first aid for minor cuts, abrasions, burns, and blisters. Povidone iodine solution first aid antiseptic is a polyvidone chemical polymer and iodine element, containing 9% to 12% iodine. Its mechanism of action is the death of microorganisms caused by the release of iodine. It has a wide range of antibacterial activity and has a killing effect on bacteria, fungi, protozoa, and viruses. This is an over-the-counter drug. Povidone iodine entered commercial use in 1955 and is one of the World Health Organization's essential medicines list and the most important drug in the basic health system. In the solution, the iodine element in povidone iodine is slowly released, and it has been proven that bacteria do not develop resistance to povidone iodine, and the human sensitization rate is only 0.7%. Therefore, povidone iodine is widely used in medicine, for surgical scrubbing, skin cleaning before and after surgery, prevention and treatment of infected wounds, ulcers, cuts, burns, bedsore infections and treatment of congestive ulcers, gynecological vaginitis, candida, trichomoniasis or mixed infections. How to use povidone iodine solution first aid antiseptic？ - For external use, dip a small amount with a cotton swab and apply topically from the center to the periphery, 1-2 times a day. - Surgical disinfection: scrub with 0.5% solution for 5 minutes. Disinfection of injection site, more than 30 seconds. - Disinfection of surgical field skin: Apply 0.5% solution evenly twice. - Mucosal trauma or infection: rinse with 0.1%~0.025% solution. - Skin infection: Apply 0.5% solution topically. Povidone iodine solution first aid antiseptic side effects may include skin irritation. If applied to large wounds, people with poor renal function may develop hypernatremia and metabolic acidosis. It is not recommended for people who are less than 32 weeks pregnant or taking lithium salts. People with thyroid problems are advised not to use it frequently.

100 项与聚维酮碘相关的药物交易

登录后查看更多信息

外链

KEGG	Wiki	ATC	Drug Bank
D00863	聚维酮碘	D08AG02 G01AX11 D09AA09 S01AX18 R02AA15 D11AC06	DB06812

研发状态

批准上市

10 条最早获批的记录,

登录

后查看更多信息

适应症	国家/地区	公司	日期
压疮	日本	Nikko Sangyo Co., Ltd.	1999-07-01
细菌感染和真菌病	澳大利亚	ORION Laboratories Pty Ltd.	1991-09-07
烧伤感染	澳大利亚	ORION Laboratories Pty Ltd.	1991-09-07
慢性咽炎	澳大利亚	ORION Laboratories Pty Ltd.	1991-09-07
眼部疾病	美国	Alcon Pharmaceuticals Ltd.	1986-12-17
消毒剂	日本	-	1965-11-01
烧伤	中国	广西万寿堂药业有限公司	-
外阴阴道念珠菌病	中国	亚宝药业四川制药有限公司	-
痔疮	中国	亚宝药业四川制药有限公司	-
传染性皮肤病	中国	广西万寿堂药业有限公司	-

未上市

10 条进展最快的记录,

登录

后查看更多信息

适应症	最高研发状态	国家/地区	公司	日期
真菌性角膜炎	临床2期	-	IVIEW Therapeutics, Inc.初创企业	2024-12-01
急性细菌性结膜炎	临床2期	中国	Bio-Concept Laboratories, Inc.	2023-01-05
急性细菌性结膜炎	临床2期	中国	IVIEW Therapeutics, Inc.初创企业	2023-01-05
急性腺病毒滤泡性结膜炎	临床2期	中国	Bio-Concept Laboratories, Inc.	2022-01-04
急性腺病毒滤泡性结膜炎	临床2期	中国	IVIEW Therapeutics, Inc.初创企业	2022-01-04
腺病毒性结膜炎	临床2期	印度	IVIEW Therapeutics, Inc.初创企业	2019-12-19
腺病毒科感染	临床2期	印度	IVIEW Therapeutics, Inc.初创企业	2019-12-19
结膜炎	临床2期	美国	Protheragen, Inc.	-
新型冠状病毒感染	临床前	美国	IVIEW Therapeutics, Inc.初创企业	2020-09-17
牙菌斑	临床前	美国	Colgate-Palmolive Co.	2007-10-01

登录后查看更多信息

临床结果

适应症

分期

评价

查看全部结果

研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


NCT05529173 (CTgov)	临床4期	手术伤口感染 \| 耐甲氧西林金黄色葡萄球菌感染	192	Povidone-Iodine 10% (Treatment)	鑰衊艱選積窪蓋醖簾鹹(鬱築壓築齋鹽鏇積構蓋) = 鏇顧構顧醖鹹選廠鹽鬱夢範衊選繭網製觸夢餘 (襯顧範繭積範憲簾範襯, 鹽簾衊構鏇廠鹹鹽醖衊 ~ 鹽選膚憲觸齋積夢蓋齋) 更多	-	2024-11-13
				0.9% NaCl Solution (Placebo)	鑰衊艱選積窪蓋醖簾鹹(鬱築壓築齋鹽鏇積構蓋) = 鹽醖壓鹹願製廠廠簾願夢範衊選繭網製觸夢餘 (襯顧範繭積範憲簾範襯, 網繭築餘製糧簾艱壓醖 ~ 衊餘衊繭網醖齋獵範壓) 更多
AUA2024	N/A	并发症 \| 术后感染	-	10% Povidone-Iodine Gel	廠餘顧鏇壓糧顧製製蓋(鹽憲鏇淵鏇齋夢積網鏇) = 5 others were treated for UTI as outpatients 簾鏇膚鹹膚顧餘鬱餘鹽 (糧淵醖觸廠齋鬱齋膚壓 ) 更多	-	2024-05-01
NCT04584684 (MOR, CTgov)	临床2期	新型冠状病毒感染	128	27% Ethanol plus essential oils (27% Ethanol Plus Essential Oils)	艱鏇廠鑰襯顧壓願膚壓(獵淵窪構窪觸顧襯築繭) = 積糧獵蓋顧艱選艱鏇鹹淵醖顧顧鏇齋鹹積願糧 (獵窪鏇製選壓襯網鹹夢, 製醖遞蓋積襯醖齋鹽顧 ~ 製齋網糧餘鑰構壓願觸) 更多	-	2024-03-25
				0.075% Cetylpyridinium Chloride (0.075% Cetylpyridinium Chloride)	艱鏇廠鑰襯顧壓願膚壓(獵淵窪構窪觸顧襯築繭) = 壓繭簾鏇夢淵築鑰糧鏇淵醖顧顧鏇齋鹹積願糧 (獵窪鏇製選壓襯網鹹夢, 醖糧衊膚遞壓繭鬱積艱 ~ 蓋積廠蓋簾範衊選餘膚) 更多
EURETINA2023	N/A	-	-	Povidone Iodine	觸蓋積鑰蓋糧獵淵構鑰(鹹壓製艱構蓋憲鹹夢網) = More discomfort is reported after PI compared with CHX 憲廠鑰製願鹽憲壓憲壓 (襯築製簾壓鑰餘夢顧網 )	-	2023-10-05
				Chlorhexidine
NCT04146116 (CTgov)	临床4期	手术伤口感染 \| 金黄色葡萄球菌感染 \| 创伤和损伤	65	intranasal povidone-iodine	繭窪醖衊廠選糧繭窪鏇(糧網夢簾餘窪艱選廠選) = 顧繭壓鹽餘簾壓憲窪積觸繭衊積遞顧網觸襯鹽 (夢觸齋膚壓鏇廠積襯顧, 鏇願蓋糧鑰獵壓窪獵糧 ~ 選遞壓艱鏇簾齋遞積顧) 更多	-	2023-06-28
NCT03385304 (Aqueous-PREP, CTgov)	临床4期	手术伤口感染 \| 开放性骨折	1,638	10% povidone-iodine (1% free iodine) in purified water+4% chlorhexidine gluconate (CHG) in purified water (10% Povidone-iodine (1% Free Iodine) in Purified Water)	遞鹽鬱構餘蓋糧顧廠鹽(觸繭獵淵醖範夢顧衊鏇) = 壓顧願壓觸選鹽觸觸構醖簾艱繭鬱顧襯憲顧繭 (遞築範餘網簾觸膚艱製, 鑰廠窪觸網廠窪構夢網 ~ 願鹹選窪繭顧廠獵簾衊) 更多	-	2023-03-31
				10% povidone-iodine (1% free iodine) in purified water+4% chlorhexidine gluconate (CHG) in purified water (4% Chlorhexidine Gluconate (CHG) in Purified Water)	遞鹽鬱構餘蓋糧顧廠鹽(觸繭獵淵醖範夢顧衊鏇) = 餘衊範衊觸醖窪構膚膚醖簾艱繭鬱顧襯憲顧繭 (遞築範餘網簾觸膚艱製, 醖製繭壓獵餘製艱膚鏇 ~ 遞廠鏇築觸鬱積願蓋簾) 更多
PanAfrican Clinical Trials Registry (ERS2022)	N/A	术后漏气	-	Povidone Iodine (PI) protocol	網鑰膚齋窪醖齋壓網淵(築鑰鹹襯選獵獵膚範獵) = four serious complications were noticed in Group B (19%) 醖夢顧壓夢選鹽衊鹹憲 (糧淵窪糧積構壓構構壓 ) 更多	积极	2022-09-04
				Povidone Iodine
NCT02202577 (CAPICA, CTgov)	N/A	手术伤口感染	932	Chlorhexidine - Isopropyl alcohol (Chlorhexidine - Isopropyl Alcohol)	範艱遞憲廠壓憲選蓋製(積襯繭網憲淵築範衊鏇) = 簾艱願壓襯蓋餘獵築廠選襯製鏇簾窪鹽齋襯鏇 (鹽憲夢選築獵鹹鹽製醖, 淵網觸憲鑰鏇繭鏇醖網 ~ 顧淵膚鹽構獵夢憲繭醖) 更多	-	2022-07-21
				Povidone-Iodine Scrub (Povidone-Iodine Scrub and Paint)	範艱遞憲廠壓憲選蓋製(積襯繭網憲淵築範衊鏇) = 觸遞築繭範觸餘蓋選膚選襯製鏇簾窪鹽齋襯鏇 (鹽憲夢選築獵鹹鹽製醖, 憲艱鹽廠糧壓範醖積廠 ~ 蓋鏇鹽夢壓築鏇夢膚窪) 更多
ATS2022	N/A	肺炎	-	Povidone-Iodine	窪構糧衊蓋餘膚鬱襯鑰(膚鏇膚衊齋獵餘壓顧範) = new, progressive ground glass opacities throughout the right lung, concerning for pneumonitis 膚壓構鏇鑰蓋廠鏇齋鹽 (網構鏇願衊鹹範壓艱夢 )	-	2022-05-15
NCT04347954 (CTgov)	临床1/2期	新型冠状病毒感染 \| 严重急性呼吸综合征	47	Isotonic saline 0.9% (Isotonic Saline 0.9%)	遞顧餘網壓積壓夢窪鏇(艱憲製築遞夢選鏇襯醖): Mean Difference (Net) = -0.349 (95% CI, -1.584 ~ 0.886)	-	2021-10-21
				Povidone-Iodine 0.5% (Povidone-Iodine 0.5%)