Conjugated estrogen is an active pharmaceutical ingredient that contains a mixture of steroidal and non-steroidal components that are obtained from pregnant mares’ urine. Conjugated estrogen is used as an external source and is prescribed as a replacement of female natural hormones. Estrogen has many well-known effects on the tissues of the body. It causes the growth of the inner lining of uterus, secretion of cervix, development & growth of female sexual organs and maintains the sexual characteristics of females, such as hair growth of underarm and pubic area and countering of body and bone. Menopause is diagnosed when a woman has not had menses for one year. Due to the low production of estrogen in the body, about 85% of women have symptoms such as hot flushes, bone loss, vaginal dryness and shrinkage of tissues.
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High Expectations for Market Development Due to Increased End User Demand
The global market for conjugated estrogen is expected to grow at a high rate over the forecast period. Rising population of ageing women with menopause and the rising demand for treatment-related menopause are driving the growth of the conjugated estrogen market. Women with menopause are at a high risk of cardiovascular disease and osteoporosis due to the low production of estrogen in the body. Decreased production of estrogen causes loss of bone density, which in turn causes osteoporosis and fractures in women.
Conjugated estrogen is well-known as an external source and is prescribed as a replacement for female natural hormones. It can be helpful to maintain and balance women health and deal with the symptoms caused by menopause. However, conjugated estrogen is not prescribed to women who have undergone surgical removal of the uterus as estrogen promote abnormal thickening of the lining of the uterus, which can increase the risk of endometrial cancer. But the combination of progestin with estrogen can prevent endometrial cancer. Also, there is a high risk of memory loss and disturbance of thinking process among women over age 65 treated with conjugated estrogen. These factors can retrain the growth of the conjugated estrogen market.
What Trends are Driving Global Market?
Menopause is a natural and normal process in women, which occurs due to aging and lowers the function of ovaries and lowers the levels of estrogen and other hormones in the body. The growing prevalence of the female geriatric population and women with menopause is the major factor driving the growth of the conjugated estrogens market over the forecast period. However, limited awareness and negligence about women healthcare services in developing nations and related side effects among women due to menopause hormone treatment therapy are restraining the revenue growth of the global conjugated estrogen market.
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For these symptoms, menopause hormone treatment therapy is the most effective treatment. Conjugated estrogen helps menopausal women treat symptoms such as shrinkage of vaginal tissue, vaginal dryness, hot flashes, bone loss and painful intercourse. However, there are many side effects of conjugated estrogen such as breast swelling, abdominal pain, vaginal bleeding, nausea and mood swings. Patients with heart & kidney diseases should be careful while taking conjugated estrogen as it causes retention of salt & water in the body. Also, a high dose of conjugated estrogen can cause clotting of blood in legs and lungs.
Some of the key players in the global conjugated estrogen market include Pfizer Inc., Teva Pharmaceuticals USA, Inc., Xi'an sgonek biological Technology Co., Ltd., Teva Branded Pharm and others.
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