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The overall objectives are to explore the safety and efficacy of Reverse Transcriptase Inhibitors Tenofovir (TDF)/ Emtricitabine (FTC) administered in AGS affected children 2 to 18 years of age.

开始日期2025-12-01

申办/合作机构

The Children's Hospital of Philadelphia

[+5]

CTR20211144 / Terminated临床1期

一项在晚期实体瘤或非霍奇金淋巴瘤受试者中评价 ATG-019（单药或联合烟酸）安全性和耐受性的I期开放性研究

评价 ATG-019（PAK4 和NAMPT 的双重抑制剂）在晚期实体瘤或非霍奇金淋巴瘤受试者中的安全性和耐受性

开始日期2022-06-30

申办/合作机构

Karyopharm Therapeutics, Inc.

[+2]

100 项与 Emerson Resources, Inc. 相关的临床结果

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0 项与 Emerson Resources, Inc. 相关的专利（医药）

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2

项与 Emerson Resources, Inc. 相关的文献（医药）

Pharmaceutical Technology

The use of acrylic resins for improved aqueous enteric coating

作者: Signorino, Charles A. ; Barkley, Aaron ; Forcellini, Lou ; Levine, Stephen

Recent technol. improvements have made acrylics the preferred system for the aqueous enteric coating of tablets.The use of acrylic enteric emulsions in aspirin was studied.Three commonly marketed dosages of aspirin tablets (81, 325, and 500 mg) were compacted.The anal. testing results for all three dosage forms, including both those stored at room temperature and those stored under accelerated stability conditions, with and without desiccant, were within the specified criteria for passing results.The pos. results of these tests demonstrate the advances that have been made in acrylic polymers for aqueous enteric coating of tablets.

Pharmaceutical Technology Europe

The use of acrylic resins for improved aqueous enteric coating

作者: Signorino, Charles A. ; Barkley, Aaron ; Forcellini, Lou ; Levine, Stephen

Historically, acrylic coatings were unstable and tended to agglomerate easily, making them difficult to use.Improvements in acrylic systems and the techniques used to apply them have resulted in them being widely used for aqueous enteric coatings.Acrylic resins are now more stable and can be used with glycerides as detackifiers instead of talc, making their application much easier.Color can also be incorporated into the enteric system, making a final color layer over a clear enteric film redundant.The study on the use of acrylic enteric emulsions in aspirin provides a clear indication of the improvements that have been made in these systems.The anal. testing results for all three dosage forms evaluated (81-, 325-, and 500-mg aspirin), including both those stored at room temperature and those stored under accelerated stability conditions, with and without desiccant, were within the specified criteria for passing results.The pos. results of these tests demonstrate the advances that have been made in acrylic polymers for aqueous enteric coating of tablets.

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100 项与 Emerson Resources, Inc. 相关的转化医学

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