Hemiparesis

ADA, Okla., May 20, 2024 /PRNewswire/ -- Dillion Kirkland is a 31-year-old Mercy emergency medical technician who works with life-threatening injuries and illnesses every day. Last October, he found himself on the receiving end of care when he was taken to the emergency department by his own co-workers after he experienced a stroke. May is American Stroke Month and this week is National EMS Week, making Kirkland's story important and reinforcing stroke awareness and treatment through in-person and virtual care. For his complete story and video, click here. Continue Reading "I'm 31, I can't be having a stroke. Even with all my training and experience, I couldn't process what was happening." Post this Kirkland was in the driver's seat of an ambulance after a routine patient transfer when he started feeling strange. He asked his partner, Brian Ridgway, to take the wheel. But after arriving back in Ada, Oklahoma, his symptoms continued to worsen. Kirkland's paramedic partner recognized something was seriously wrong and loaded him up in his own ambulance and took him straight to the ER. "Brian told me, 'I think you're having a stroke,' but I thought, 'I'm 31, I can't be having a stroke,'" said Kirkland. "Even with all my training and experience, I couldn't process what was happening. It progressed to where I couldn't speak, I couldn't formulate a sentence, everything was garbled and delayed. What I wanted to say in my brain just wouldn't come out of my mouth." According to the Centers for Disease Control and Prevention, someone experiences a stroke every 40 seconds in the United States, and stroke remains one of the leading causes of death and long-term disability. While stroke risk increases with age, a stroke can occur at any age. After Kirkland arrived in the Mercy Hospital Ada emergency department, he was evaluated and connected with a Mercy Virtual neurologist. Sensing the urgency of the situation, the virtual neurologist rushed the local team to administer a beta-blocker to lower blood pressure and a clot-dissolving stroke medication called Tenecteplase (TNK). "Our team quickly evaluated Dillion and gave him the medication he needed," said Dr. Advait Mahulikar, a member of Kirkland's virtual neurology team. "The quick actions and assessment of our team combined with clot-busting medication helped prevent the worsening of symptoms that could have potentially become disabling, especially at such a young age." Mercy Virtual has a team of neurologists who provide care 24/7 to 31 Mercy facilities across four states. Depending on a hospital's needs, Mercy Virtual supplements in-person neurology care or provides full neurology coverage for many rural hospitals unable to staff full-time physicians. This allows the local team to work collaboratively at a patient's bedside without spending extra time transporting them to larger trauma centers. "Virtual care has literally changed the lives of thousands of patients by providing access to a neurologist when it matters most during a time-sensitive diagnosis like stroke," said Dr. Meghan Rodden, physician lead of Mercy Virtual stroke care. "Time is brain, and a typical patient can lose 1.9 million neurons each minute a stroke is untreated. That is why it's essential that our virtual neurologists do a combination of bedside and virtual work so some of our smaller facilities can get access to the specialized care they need faster." With the help of his in-person and virtual care team, Kirkland's story has a happy ending. "After the TNK medication was administered, my symptoms were resolved within 30 minutes, and I've fully recovered with no deficits to this day," he said. "TNK was actually a relatively new standard of stroke care. It was something we had recently discussed as an EMS team, but I had yet to see it in action, so it was scary to try it myself firsthand. I'm a firm believer in TNK now." While Kirkland didn't have the typical stroke symptoms of one-sided weakness, he had overall coordination loss, garbled speech and an extremely elevated blood pressure. Mercy recommends the acronym B.E.F.A.S.T. if someone is believed to be having a stroke. B – Balance: Does the person complain of sudden dizziness or difficulty walking? E – Eyes: Does the person complain of blurred vision, seeing dark or bright spots? F – Face: Ask the person to smile. Is the smile even or lop-sided? A – Arms: Ask the person to raise both arms. Does one arm drift downward? S – Speech: Ask the person to repeat a simple phrase. Is the speech slurred or strange? T – Time: If you see any of these signs, call 9-1-1 right away and note the time. Observers should record the time when any symptoms first appear to help health professionals plan the best treatment and minimize long-term stroke damage. Kirkland is back at work saving lives, but he hopes sharing his story will help spread awareness. "Knowing the signs is important for everyone and can make a big difference in recovery or even between life and death," Kirkland said. "When in doubt, call 9-1-1 and seek medical attention." About Mercy Mercy, one of the 20 largest U.S. health systems and named the top large system in the U.S. for excellent patient experience by NRC Health, serves millions annually with nationally recognized care and one of the nation's largest and highest performing Accountable Care Organizations in quality and cost. Mercy is a highly integrated, multi-state health care system including more than 50 acute care and specialty (heart, children's, orthopedic and rehab) hospitals, convenient and urgent care locations, imaging centers and pharmacies. Mercy has over 900 physician practice locations and outpatient facilities, more than 4,500 physicians and advanced practitioners and 50,000 co-workers serving patients and families across Arkansas, Kansas, Missouri and Oklahoma. Mercy also has clinics, outpatient services and outreach ministries in Arkansas, Louisiana, Mississippi and Texas. In fiscal year 2023 alone, Mercy provided more than half a billion dollars of free care and other community benefits, including traditional charity care and unreimbursed Medicaid. SOURCE Mercy

The fourth quarter of the year is a fitting time to look back and look ahead to consider investment trends in healthcare and what to expect in 2024. In response to emailed questions, investors shared perspectives based on companies they’ve backed and areas of increasing interest. Investment in healthcare is also a big theme at the HLTH event taking place October 8-11 at the Las Vegas Convention Center. Click here to view the agenda, speakers, exhibitors and to register. Here is a look at some of the HLTH panel discussions relating to investment. The AI Hype Cycle Coaster Sunday, October 8, 1:10 pm to 1:50 pm The AI hype cycle promises a wild ride and health investors have been quite the thrill seekers. The healthcare AI market is expected to reach over $102 billion by 2028, ushering in a flood of new solutions claiming to have the ability to transform our broken industry. In a drying up funding environment, AI has been our life source. Will the thrill ride end or are we in for a long journey? Experts dive into all the factors at play to determine if this trend of extreme optimism is warranted or if the skeptics will prevail. The Great Leveling Out Monday, October 9, 11:00 am to 11:40 am The first half of 2023 resulted in a 33% drop in digital health funding, leaving us on track for the lowest funding year since 2019. There is less money to go around and fewer investors cutting checks, but all hope is not lost. Like a phoenix rising from the ashes, there will be several resilient companies with strong business models, sound leadership and just the right idea to come out on the other side of this market lull. So who is making it to the other side and who will be left behind in the digital health graveyard? Bessemer Venture Partners will unveil the data from an inaugural State of Health Tech report, and chat live on stage with top investors about all things over-hyped, over-funded, and overvalued to level the playing field as we go into 2024. “The recent decline in healthcare technology venture capital funding and public market stocks provides an understandable reason for a ‘glass half empty’ view on the market. But we are optimistic and looking at the bigger picture: overall health tech funding is six times what it was when I started investing in the sector in 2012,” Steve Kraus, Partner, Bessemer Venture Partners said. “Like any maturing market, there are changes and pivots we need to make to build a resilient future for healthcare innovation, and lots to learn from the last few years. We dive into these market dynamics, benchmarks, and best practices for health tech businesses and the trends we see emerging for 2024 in our State of Health Tech report.” Who Runs the World… of Health Monday, October 9, 11:50 am – 12:30 pm Despite women constituting 50% of the population, a mere 1% of healthcare research and innovation investment is directed towards female-specific conditions beyond oncology. There is the clear societal need and sound business case for more health services and solutions for the specific health needs of women from menstruation to menopause to vaginal health. As most investment firms remain male-dominated, pitching solutions — like a smart menstrual pad — to a room of men is not that simple. Leaders have not let that stop them and are proving that investing in women’s health is not just imperative for improving the lives of women globally, but it also presents tremendous opportunities for value creation. Hear us roar! A Storm of Megadeals Monday, October 9, 1:20 pm to 2:00 pm Digital health stocks started 2023 trading almost 50% lower than they did at the start of 2021, making a public send off look a lot less appealing to startups teetering on the edge of an exit. While the public markets have chilled, the consolidation space is just heating up, with more than half of deals in the first half of the year being mega-deals, rounds worth $100M or more. As the healthcare landscape is being reshaped by new technologies, a tense political environment, and economic uncertainty, companies are making bold moves to adapt their business models for long-term success. The FTC has certainly taken notice and in turn, put healthcare deal-making on notice, with proposed changes on the horizon that can directly impact deal volume. Analysts, investors and bankers all have a hot take on this fluctuating digital health weather pattern! Jon David Friedland is a partner with Cleveland Clinic Innovations focused on medical device investments. What types of medical device technology are you interested in? “Our priorities in medical device investing are well aligned with our clinical and research strengths at Cleveland Clinic, as the majority of our portfolio companies are licensees of Cleveland Clinic intellectual property. Most of these companies are in what we call our three ‘power alleys’ of medtech: structural heart, neurostimulation and surgical visualization and navigation.” What criteria do you look for? “We have a fairly exhaustive list of objective criteria against which we evaluate our proposed investment, which includes large target markets, strong intellectual property, a unique, proprietary and economically compelling solution, a clear regulatory pathway and technology that has significant potential to enhance patient care. For opportunities that do not originate at Cleveland Clinic, it is critical for us to identify a subject matter expert at Cleveland Clinic (a clinician or researcher) who is willing to champion the opportunity.” What are some examples of recent investments? “We led a Series B investment in Enspire DBS, which is initiating its Phase II study for deep brain stimulation as a therapy for treatment of hemiparesis in ischemic stroke patients (a peer-reviewed paper was also recently published in Nature Medicine describing the impact on patients enrolled in the Phase I study). “We also participated in a funding [round] for MediView XR alongside GE Healthcare, Mayo Clinic Ventures and others to support the development and commercialization activities. The company recently received 510(k) clearance for its flagship XR-90 visualization solution.” What healthcare investment trends and deals for the year to date do you find particularly interesting? “Artificial intelligence (especially generative AI) has been the hot phrase of late, but we have been commercializing and supporting a range of AI-enabled solutions long before it became trendy. “Our thesis around surgical visualization & navigation is built on the premise that the operating room will continue to see transformative advances that will improve patient outcomes, provide better information to the clinician and expand the scope and population of clinical users to continue to advance medicine, a hallmark of our Innovations strategy.” Julien Pham is founder and managing partner of Third Culture Capital Looking back on what has transpired this year, what are some of the emerging medtech and diagnostics trends that you’re seeing? “We have seen a steady supply of diagnostic tools and solutions in our dealflow despite the fact it is the sector that is a bit less predictable because it relies on regulatory steps, a robust supply chain, and manufacturing capabilities, compared to a traditional digital health startup. “The economic environment, i.e. inflationary patterns, and certain societal shifts, have put pressure on the sector. Particularly the experience of confinement during the pandemic, the evolving trend of remote work, and challenges to the supply chain that are finally showing signs of recovery, might forever affect the sector. “Trends I see emerging include more interest in ‘at home’ diagnostic solutions, further and deeper merging of technology and traditional diagnostics, which could result in development and increased adoption of biosensor technologies, and continued interest in digital companion diagnostics alongside existing and new medications.” Did your firm make any investments in companies in areas you previously had not invested in? “Yes, we invested in Zuri Fertility, a Chicago-based care navigation solution for fertility care.” What are some of the criteria that guide your investments? “We invest in seed and pre-seed stage health tech and techbio companies that are innovating in areas where access to care is lacking or not equitable, and whose market or utilization is anticipated to grow, as a result of more adoption of novel technologies, novel business models, and optimized care workflows. “Ultimately, we frame our investment objectives around the Quadruple Aim of improving outcomes for patients, reducing the cost of care delivery, and improving the experience of care for patients and providers.” Looking ahead, what are some of the challenges and positive developments that could affect healthcare investment in the next 12 months? “Some of the challenges in the next 12 months will likely continue to be related to economic uncertainty. We do think that early stage startups will be able to raise capital at reasonable valuations but will need to scale in a more frugal way. “I am also excited to see how we explore the use of AI and specifically generative AI in early experiments in digital health. I’m not quite sure generative AI for care delivery is quite ready for prime time yet. “ Oliver Keown is managing director with Intuitive Ventures Looking back on what has transpired this year, what are some of the emerging medtech and diagnostics trends that you’re seeing? “We see increasing awareness of the threat levels and need for more sophisticated cybersecurity for medical devices solutions. Also, [there is] lots of renewed enthusiasm for AI in healthcare — driven, of course, by the generative AI hype. But also an accelerating acceptance and adoption of startup solutions that have been working hard for some time on real-world applications and evidence-building for AI-powered clinical decision support and diagnostics.” Did your firm make any investments in companies in areas you previously had not invested in? “We invested in Capstan Medical, a future leader in the field of structural heart and endovascular robotics that is pioneering new therapies that will increase access to an underserved population.” Looking ahead, what are some of the challenges and positive developments that could affect healthcare investment in the next 12 months? “Intuitive Ventures is bullish for the future. Deals might continue to take a while to close and some investors will remain risk averse, but there is capital available for great teams and technologies serving large unmet needs.” If you’d like to be part of the investment trends conversations at HLTH, click here to view the agenda, speakers, exhibitors and to register.

ORLANDO, Fla., Oct. 02, 2023 (GLOBE NEWSWIRE) -- Aviv Clinics, one of the world’s most advanced brain clinics, shares the results of a new case report showing a unique hyperbaric oxygen therapy (HBOT) protocol was effective for improving hand motor function in a chronic post-stroke patient. The case report, Functional MRI evaluation of hyperbaric oxygen therapy effect on hand motor recovery in a chronic post-stroke patient: a case report and physiological discussion, was conducted by a research team at the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center and Tel Aviv University, and published in Frontiers in Neurology. The case report evaluated the effect of a unique HBOT protocol to induce motor rehabilitation in a chronic post-stroke patient with severe upper-limb motor impairment. The patient was a 61-year-old right-handed male patient who was suffering with right hemiparesis (physical weakness or the inability to move one side of the body) two years after his stroke. The case report analyzed the patient’s functional MRI (fMRI) to evaluate the neural response mechanisms and functional reorganization of the patient’s brain following HBOT. The fMRIs were evaluated pre- and post-HBOT treatment, which included 60 daily sessions over 12 weeks. The patient’s motor function was assessed at baseline and after treatment using the Fugl–Meyer assessment (FMA), a validated post-stroke assessment, and the handgrip maximum voluntary contraction (MVC). Results of the case report showed that following the HBOT protocol, the patient’s FMA score improved from 17 (severe impairment) to 31 (moderate impairment), and there was an increase in fMRI activation in both the supplementary motor cortex (SMA) and the premotor cortex (PMA), bilaterally. Additionally, analysis showed increased connectivity between the two hemispheres and between specific regions in the hemisphere which was not injured. “In our current healthcare system, the focus is on teaching chronic stroke patients how to compensate and live with their post-stroke symptoms rather than stimulating neuroplasticity to recover and heal those symptoms,” said Dr. Amir Hadanny, Chief Medical Officer at Aviv Scientific and Chief Medical Research Officer at the Sagol Center. “With the specific HBOT protocol that we’re using, we see evidence that we can repair brain connectivity and see real improvements in post-stroke symptoms. Stroke patients shouldn’t have to settle for coping with their symptoms; there may be hope and a true possibility for recovery and improvement.” HBOT is a medical treatment in which 100% oxygen is administered at an increased environmental pressure. Aviv’s unique HBOT protocol, the hyperoxic-hypoxic paradox, fluctuates oxygen levels during treatment and is being used to repair and regenerate damaged brain tissue in several types of brain injuries including stroke, traumatic brain injury, PTSD, long COVID and age-related cognitive decline, among others. A previous study from the research team at the Sagol Center for Hyperbaric Medicine and Research has demonstrated the efficacy of HBOT for improving neurocognitive function in post-stroke patients. Another randomized prospective study from this group reported significant neurological function and quality of life changes compared to the control group. Aviv Clinics offers an advanced treatment program with a multidisciplinary team of medical experts providing patients with top-line care with the goal of improving their quality of life. The Aviv Medical Program includes an in-depth assessment of the patient’s physical and neurological condition to assess their overall health. For patients that meet the criteria, the Aviv team prepares a comprehensive, personalized treatment schedule combining HBOT with cognitive and physical training and dietary coaching, for a holistic approach to patient health. The HBOT sessions are conducted in state-of-the-art multiplace chambers that are comfortable, safe and allow for medical staff to accompany patients during the treatment. The elevated pressure in the HBOT chamber creates an optimal oxygenation condition, ultimately providing damaged brain and body tissues the environment necessary to heal. The full study is available here. For more on Aviv Clinics, visit aviv-clinics.com. About Aviv Clinics Aviv Clinics is the leader in the research and treatment of age-related cognitive and functional decline and novel applications of hyperbaric oxygen therapy (HBOT) to maximize human performance. Based on an exclusive partnership with the world’s largest hyperbaric medicine and research facility, the Sagol Center at Shamir Medical Center in Israel, Aviv is introducing a global network of clinics delivering the most effective evidence-based treatment of age-related decline—the Aviv Medical Program. The three-month regimen was developed based on over a decade of research and thousands of patients treated worldwide under the scientific leadership of Shai Efrati, M.D., chair of Aviv Scientific’s Medical Advisory Board and director of the Sagol Center. Media Contact Ellie Holt Uproar PR for Aviv Clinics eholt@uproarpr.com