预约演示
更新于：2026-09-08
Glycerin
甘油
更新于：2026-09-08
概要
基本信息
原研机构 |
非在研机构- |
权益机构- |
最高研发阶段批准上市 |
首次获批日期 中国 (1981-01-01), |
最高研发阶段(中国)批准上市 |
特殊审评- |
登录后查看时间轴
结构/序列
分子式C3H8O3 |
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N |
CAS号56-81-5 |
关联
76
项与 甘油 相关的临床试验CTRI/2026/07/113822
A Prospective, Multicenter, Randomized, Assessor Blind, Parallel-group, Active-Controlled, Phase III Comparative Study to Evaluate the Efficacy and Safety of Carboxymethyl Cellulose Sodium 0.5 % w/v and Glycerin 1% w/v Eye Drops of Sun Pharmaceutical Industries Ltd. in Comparison to Refresh Optive Mega-3 Eye Drops (Carboxymethyl Cellulose Sodium 0.5 % w/v and Glycerin 1% w/v) in Treatment of Patients with Dry Eye Disease. - NIL
TCTR20260723009
The Impact of Intradermal Injection of Hyaluronic Acid Combined with Glycerol on the Facial Skin Microbiome in Patients with Mild Acne Vulgaris
NCT06955130
Lactate and Glycerol Contribution to Gluconeogenesis
100 项与 甘油 相关的临床结果
登录后查看更多信息
100 项与 甘油 相关的转化医学
登录后查看更多信息
100 项与 甘油 相关的专利（医药）
登录后查看更多信息
85,242
项与 甘油 相关的文献（医药）2026-12-15International Journal of Green Pharmacy
Phytochemistry, pharmacological potential, and therapeutic uses of (Palash) Butea monosperma: A review
作者: Kumar, Susheel ; Upadhyay, Ravi Kant
Since last ten decades various synthetic pesticides were used for insect control but most of them were found highly toxic and harmful to non-target living beings.These also persist for longer time inside soil as bound residue and enter into food chain and reach to human body and evoke certain diseases.Plant species synthesize thousands of dynamic biomols. and so numerous of them have been extracted and distinguished for its insecticidal exercises.In the present investigation, various field bioassays were performed to observe the anti-termites efficacy of plant essential oils based formulations to control population of Indian white termite.Combinatorial mixtures of Tagetes erecta essential oils have shown synergistic activity against termites.LD50 values obtained in mixtures B-AST- and S-AST-C were in a range of 261.930 to 507- 666.For the control of termite infestation, thread-binding assay was found quite effective to control garden termite.Bait formulation was also used which cut down termite infestation in various crop fields.T. erecta extract with different combinatorial mixtures provides sustainable way of termite control.Use of crude essential oils, its active components, and combinatorial mixtures have shown significant anti-termites efficacy against Odontotermes obesus.In subsequent bioassays, both crude essential oils, its active components and combinatorial mixtures, have shown high toxicity and repellency against Odontotermes obesus.
2026-09-01Journal of Vascular Surgery-Venous and Lymphatic Disorders
Inframalleolar venous ulcers heal with Unna boot therapy
Article
作者: Ascher, Enrico ; Robbins, Justin M ; Hingorani, Anil ; Karren, Camille L ; Ascher, Alexandra N ; Gill-Jones, Nisha D S
BACKGROUND:
This study highlights the presentation of inframalleolar ulcers in venous disease, their wound healing factors, recurrence rate, and response to Unna boot treatment with adjunct endovenous and/or iliac vein stenting treatments.
METHODS:
This retrospective single-center study included 71 office-based patients with inframalleolar venous ulcers treated between May 2012 and May 2023. Of the 71 patients evaluated, 12 presented with bilateral ulcers, resulting in a total of 83 limbs treated. Patient demographics including age, sex, ulcer etiology, ulcer location, diabetes status, and treatment modality were evaluated. All patients presented with bilateral leg swelling and venous reflux greater than 500 ms suggestive of venous insufficiency. Initially, patients were required to have palpable pedal pulses and a normal ankle-brachial index (ABI) for inclusion. Over time, inclusion criteria were broadened to accept patients with mixed arterial venous disease, provided their ABI was greater than 0.6. Patients with isolated arterial pathology and an ABI <0.6 and those with diabetic neuropathic ulcer etiology were excluded from this study. Patients received compression therapy that included an elastic all-cotton elastic wrap and an inelastic Unna boot formulated with calamine, zinc oxide, and glycerin, both applied by trained medical assistants. Sixty-five patients received additional endovenous and/or iliac vein stenting treatments.
RESULTS:
The mean patient age was 67 ± 14 years (range, 25-96 years). Of the 71 patients treated, 12 (16.9%) presented with ulcers on both limbs, resulting in a total of 83 limbs treated. All ulcers were treated with weekly Unna boots, with an average treatment duration of 12 ± 23 weeks (range, 1-181 weeks) and a median treatment duration of 5 weeks. After wound healing, patients were followed for a mean duration of 16 ± 28 months. The success rate of >90% healing for inframalleolar ulcers was 51.8%. Factors associated with wound healing were ulcers that were primarily venous in nature as opposed to mixed (P = .01). Heel ulcers were not associated with inferior wound healing (P = .10) compared with other locations but were associated with higher rates of recurrence (P = .002). In total, 26.76% of patients had recurrent ulcers, whereas 45.13% did not; 8.4% of ulcers were still actively being treated with Unna boots, and 19.71% of patients were lost to follow-up. Improved healing of inframalleolar ulcers was significantly associated with the presence of a concomitant supramalleolar ulcer on the same limb (P = .02).
CONCLUSIONS:
This study brings attention to the uncommon presentation of inframalleolar ulcers in venous stasis disease and is driven by the observation that bilateral leg swelling can lead to poor wound healing. Compression therapy using Unna boots is easily accessible, cost-effective, and should be considered as it offers significant therapeutic benefit in this patient population.
2026-08-04LANGMUIR
Spreading Dynamics
of Binary Solution Droplets on
Heated Curved Surfaces: Experiments and Numerical Simulations
Article
作者: Xu, Nian ; Chu, Huaqiang ; Zhou, Xiangjun ; Chen, Jun ; Ge, Yuqing
Abstract:
Efficient thermal management is critical for high-power electronic devices, and droplet impact boiling has emerged as a highly efficient cooling method because of its exceptional heat transfer capability driven by phase change dynamics. The alcohol droplet impacts on curved surfaces are crucial for optimizing spray cooling and surface coating, as well as for understanding multiphase flow interfaces. This study focuses on binary solution droplets composed of water and ethanol with low-concentration glycerol added as an additive. Experiments and numerical simulations analyze the impact behavior dynamics and heat transfer mechanisms of the droplets, which are influenced by the surface morphology, wettability, temperature, and impact height. Research indicates that the convex surface exhibits a combined advantage over the flat and concave surfaces in promoting droplet spreading and a concentrated rebound pattern. The hydrophobic convex surface suppresses droplet spreading and facilitates the bouncing. The synergistic interaction between the convex surface and temperature intensifies droplet heat transfer and phase transition processes, yielding five distinct impact regimes. A higher Weber number correlates with greater droplet spreading, faster morphological changes, higher bouncing heights, and shorter rebound onset times. Concurrently, the synergistic effect of surface temperature and Weber number determines the intensity of the droplet morphological transformations. Binary solution droplets with high glycerol concentrations exhibit more pronounced suppression of spreading, while their morphological changes and degrees of breakup after impact with the heated convex surface are significantly exacerbated. For binary solution droplets with varying glycerol concentrations, differences in the coupled effects of the droplet’s thermophysical properties significantly influence their tendency toward fragmentation.
100 项与 甘油 相关的药物交易
登录后查看更多信息
研发状态
10 条最早获批的记录, 后查看更多信息
登录
| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 便秘 | 中国 | 1981-01-01 |
登录后查看更多信息
临床结果
临床结果
适应症
分期
评价
查看全部结果
临床4期 | 40 | (Empagliflozin) | 糧餘憲鏇夢願構製遞壓 = 膚壓窪蓋顧憲繭壓繭選 衊壓選廠願獵願遞網糧 (衊顧選顧鏇糧範製獵鹽, 鑰構窪製鬱觸艱齋鬱蓋 ~ 積蓋鹽鹽鑰壓鏇襯觸夢) 更多 | - | 2019-05-02 | ||
Placebo (for Empagliflozin)+[U-13C3] glycerol (Placebo) | 糧餘憲鏇夢願構製遞壓 = 築壓餘襯膚選壓衊艱衊 衊壓選廠願獵願遞網糧 (衊顧選顧鏇糧範製獵鹽, 選願壓憲憲簾簾膚窪廠 ~ 願鹹鏇鹹選鬱齋簾窪獵) 更多 | ||||||
N/A | 22 | (Treatment Program) | 壓糧膚壓鬱顧齋糧糧糧 = 廠繭築餘積壓鬱糧顧壓 網憲蓋網網鏇膚繭鏇壓 (醖艱選憲鏇構艱壓鹽遞, 繭餘齋範衊鬱糧糧網艱 ~ 淵繭積鑰夢鹽糧範獵鬱) 更多 | - | 2018-01-11 | ||
(Waitlist Control) | 壓糧膚壓鬱顧齋糧糧糧 = 觸醖觸壓齋鏇鏇範鹽襯 網憲蓋網網鏇膚繭鏇壓 (醖艱選憲鏇構艱壓鹽遞, 鬱遞繭鏇鑰獵簾鑰遞獵 ~ 餘積鏇憲願願網壓廠獵) 更多 | ||||||
N/A | 16 | (New Formulation of Glycerin 1% Eye Drop) | 蓋壓憲積齋鬱鬱膚壓憲(襯鬱淵齋膚鬱糧廠構鹽) = 鑰餘遞積襯艱願衊蓋壓 醖積廠觸鬱憲鏇範鬱鹽 (膚鬱網鏇構壓鬱製淵齋, 27.21) 更多 | - | 2012-10-26 | ||
Propylene Glycol+PEG 400 (Propylene Glycol and PEG 400 Eye Drop) | 蓋壓憲積齋鬱鬱膚壓憲(襯鬱淵齋膚鬱糧廠構鹽) = 憲衊築築繭艱襯獵鬱齋 醖積廠觸鬱憲鏇範鬱鹽 (膚鬱網鏇構壓鬱製淵齋, 30.30) 更多 | ||||||
N/A | 228 | Carboxymethylcellulose+Glycerin (Carboxymethylcellulose and Glycerin Based Artificial Tear) | 構齋糧壓糧憲選廠鑰簾(糧簾餘鏇鏇齋廠淵簾壓) = 壓齋鹽鏇膚蓋鬱艱蓋膚 構膚淵餘齋遞鏇選選築 (窪廠廠願選壓網醖範網, 11.125) 更多 | - | 2011-12-14 | ||
Carboxymethylcellulose (Carboxymethylcellulose Based Artificial Tear) | 構齋糧壓糧憲選廠鑰簾(糧簾餘鏇鏇齋廠淵簾壓) = 夢醖獵憲獵鬱簾獵壓鏇 構膚淵餘齋遞鏇選選築 (窪廠廠願選壓網醖範網, 8.036) 更多 | ||||||
N/A | 47 | (Artificial Tear Formulation 1) | 鬱顧製鹹襯簾簾獵範淵(製衊衊獵鏇獵鹽衊積鬱) = 憲壓網夢遞製遞願獵網 繭鬱獵膚繭蓋窪遞襯遞 (顧選壓繭鑰鹹艱餘衊夢, 30.01) 更多 | - | 2011-12-13 | ||
(Artificial Tear Formulation 2) | 鬱顧製鹹襯簾簾獵範淵(製衊衊獵鏇獵鹽衊積鬱) = 醖醖艱觸鏇網衊蓋製鹹 繭鬱獵膚繭蓋窪遞襯遞 (顧選壓繭鑰鹹艱餘衊夢, 26.63) 更多 | ||||||
N/A | 18 | 膚艱製鬱簾襯顧築範繭(鬱繭壓糧簾鬱衊選構鹽) = 獵餘網築願糧顧顧廠積 繭餘蓋糧網築繭觸顧廠 (顧顧構壓糧鑰鑰鹽願鬱 ) | - | 2010-06-01 | |||
膚艱製鬱簾襯顧築範繭(鬱繭壓糧簾鬱衊選構鹽) = 鬱簾憲鑰蓋廠遞顧範糧 繭餘蓋糧網築繭觸顧廠 (顧顧構壓糧鑰鑰鹽願鬱 ) | |||||||
N/A | 16 | New formulation of glycerin 1% | 憲網窪繭廠簾積築憲衊(鹹淵製積艱簾夢壓襯製) = 餘壓齋簾鏇鬱糧構廠憲 齋鑰淵蓋鬱鬱憲選憲齋 (糧願獵艱膚簾觸願齋餘 ) 更多 | - | 2009-04-01 | ||
Commercially available artificial tear formulation of propylene glycol (0.3%) and polyethylene glycol (0.4%) | 膚選繭範築簾築願餘選(簾獵鬱網膚繭繭構簾鬱) = 製憲鏇餘獵襯艱鹽鑰鑰 艱鏇鹽醖淵壓膚構壓壓 (淵蓋構窪鬱壓構襯艱襯 ) |
登录后查看更多信息
转化医学
使用我们的转化医学数据加速您的研究。
登录
或
药物交易
使用我们的药物交易数据加速您的研究。
登录
或
核心专利
使用我们的核心专利数据促进您的研究。
登录
或
临床分析
紧跟全球注册中心的最新临床试验。
登录
或
批准
利用最新的监管批准信息加速您的研究。
登录
或
特殊审评
只需点击几下即可了解关键药物信息。
登录
或
提出任何生物医药研究问题
让每一步生物医药决策都精准制胜
基于十亿级生物数据与全球情报的精准 AI，赋能早期药物发现
立即开始免费试用!
智慧芽新药情报库是智慧芽专为生命科学人士构建的基于AI的创新药情报平台，助您全方位提升您的研发与决策效率。
立即接入生物医药数据包
智慧芽新药库数据也通过智慧芽开放平台，以MCP或API服务形式对外开放。立即使用我们的MCP服务定制您的LLM智能体。
生物序列数据库
生物药研发创新
免费使用
化学结构数据库
小分子化药研发创新
免费使用