*本资料仅供医疗卫生专业人士参考,请勿向非医疗卫生专业人士发放
截至01月02日15点59分,近期共有 176 本期刊发布了 338 篇文章,其中糖尿病相关的文章共 141 篇,覆盖 20 个领域的内容。中国专家参与发表的文章有 34 篇。今日,影响因子最高的文章刊登在 Nature Reviews Cardiology (IF: 44.200) 期刊上。
今日头条
Headlines
01 Nature Reviews Cardiology IF: 44.200 优化老年衰弱患者的心血管药物治疗
Nguyen, Tu N., Woodward, Mark, Butt, Jawad H., McMurray, John J. V., Lip, Gregory Y. H., Kaski, Juan Carlos, etc.
随着全球人口老龄化进程加速,衰弱在老年人中的患病率持续上升,其对心血管结局的影响也日益受到关注。近日,发表于《自然综述·心脏病学》(Nature Reviews Cardiology)的一篇综述文章指出,针对老年衰弱患者的心血管药物治疗,面临着不同于一般人群的独特挑战,迫切需要一套全面且个体化的管理策略。
该综述由多位国际心血管疾病专家共同撰写,旨在梳理老年衰弱患者心血管药物优化治疗的核心问题。文章开篇即强调,将标准心血管诊疗模式照搬到这一特殊群体,往往会遭遇诸多困难。因此,临床决策必须超越单一的疾病管理,转而关注患者的整体功能状态与长期治疗目标。
文章系统回顾了多个关键心血管治疗领域在衰弱老年人中的应用困境。在高血压管理方面,严格的血压控制目标可能并不适用于所有衰弱个体,过度降压反而可能增加跌倒等风险。对于合并2型糖尿病的患者,过于激进的降糖策略可能导致低血糖事件频发,其危害有时甚至超过高血糖本身。此外,在降脂治疗、抗血小板药物以及用于房颤卒中预防的直接口服抗凝药应用上,都需要精细评估治疗的绝对获益与潜在出血等风险。
特别值得注意的是心力衰竭的治疗。衰弱老年心衰患者对常规药物的耐受性可能更差,更易发生肾功能恶化、低血压或电解质紊乱等不良反应。因此,药物的起始、滴定和目标剂量都需要基于患者的衰弱程度和合并症情况进行大幅调整和个体化定制。
综述明确指出,为老年衰弱患者制定心血管治疗方案的核心,在于审慎权衡减少心血管事件的明确获益与药物治疗可能带来的额外风险。这一平衡点的寻找,高度依赖于对患者整体健康状况、预期寿命、个人价值观及治疗偏好的深入理解与评估。临床医生需要与患者及其家属进行充分沟通,共同确定以患者为中心的治疗目标。
最终,该综述倡导,对于老年衰弱患者的心血管风险管理,应摒弃“一刀切”的模式,转而采纳一种更灵活、更人性化的个体化医疗路径。这要求临床医生不仅关注疾病本身,更要全面评估患者的衰弱状态、功能容量和生活质量,从而在延长寿命与维持生命尊严之间找到最佳平衡,实现真正优化的心血管药物治疗。
本文由 天纳乾坤 编辑
扫描二维码查看源文
Nature Reviews Cardiology | Ahead of Print.
10.1038/s41569-025-01244-w
02 Acta pharmaceutica sinica B IF: 14.600 ROS清除纳米材料:骨组织再生的新兴工具与近期进展全面综述
He, Wanzhuo, Xu, Tian, Wang, Miao, Ni, Ni, Su, Yun, Fan, Xianqun, etc.
近日,一项发表于期刊《Acta pharmaceutica sinica B》的综述文章,系统梳理了活性氧(ROS)清除纳米材料作为骨组织再生新兴工具的最新进展。该工作由He Wanzhuo、Xu Tian、Wang Miao、Ni Ni、Su Yun及Fan Xianqun共同完成,为应对临床常见的骨缺损修复难题提供了基于纳米技术的新视角。
骨缺损,即骨骼结构完整性的丧失,是困扰全球数百万患者的普遍临床问题。目前,临床常用的骨自体移植和异体移植虽能提供治疗可能,但仍面临供体来源有限、免疫排斥反应、解剖结构限制以及患者合并症(如糖尿病)引发并发症等诸多挑战,常导致治疗效果不尽如人意。因此,寻找替代治疗方案成为该领域的研究焦点。
研究者指出,活性氧在骨再生过程中扮演着复杂而关键的角色。生理水平的ROS是正常愈合所必需的信号分子,然而,当ROS在损伤局部过度积累时,会打破成骨与破骨活动之间的精密平衡,从而严重阻碍骨组织再生进程。理论上,应用抗氧化剂通过清除过量ROS或抑制其生成,可以缓解这种氧化应激,恢复骨骼代谢平衡,为再生创造条件。
随着纳米技术的飞速发展,多种具有增强治疗效能的ROS清除纳米材料被开发出来。这些材料主要通过两种途径发挥作用:一是作为高效的递送载体,负载并精准释放维生素C、多酚类等传统抗氧化剂至病灶部位;二是自身具备类氧化还原酶(如过氧化氢酶、超氧化物歧化酶)的催化活性或固有的抗氧化特性,能够直接中和过量的ROS。这种设计极大地提升了抗氧化治疗的效率和靶向性。
这篇综述文章旨在对这一快速发展的领域进行全面的总结与展望。文章不仅详细阐述了各类ROS清除纳米材料的设计原理与构建策略,还深入探讨了它们通过调节微环境氧化还原状态以促进骨再生的具体分子与细胞机制。同时,综述系统回顾了这些纳米材料在骨组织工程支架、水凝胶以及体内外骨修复模型中的应用研究成果,展示了其良好的应用前景。
最后,文章还客观评估了ROS清除纳米材料在走向临床转化过程中所面临的机遇与潜在挑战,包括生物安全性、大规模生产、稳定性及长期疗效验证等关键问题,为未来的研究方向提供了重要参考。这项工作有望推动基于纳米抗氧化策略的骨修复技术的发展,为改善骨缺损患者的临床预后提供新的工具选择。
本文由 天纳乾坤 编辑
扫描二维码查看源文
Acta pharmaceutica sinica B | Volume 15, Issue 12
10.1016/j.apsb.2025.09.040
03 Science advances IF: 12.500 悬浮物理学主导镰状细胞病血流的跨尺度动力学
Szafraniec, Hannah M, Bull, Freya, Higgins, John M, Stone, Howard A, Krüger, Timm, Pearce, Philip, etc.
近日,一项发表在《Science advances》期刊上的研究,为理解镰状细胞病等血液疾病中异常血流的物理机制提供了新的见解。这项研究由Hannah M Szafraniec、Freya Bull、John M Higgins、Howard A Stone、Timm Krüger、Philip Pearce和David K Wood共同完成。
研究者指出,从糖尿病到疟疾,许多疾病的临床结果不佳都与血流的改变有关。然而,由于红细胞特性在个体内部和不同个体之间存在巨大差异,长期以来,科学家们难以厘清驱动这些疾病中病理血流动态的多尺度机制。
为了突破这一瓶颈,研究团队专门开发了新型的微流控实验平台。这一技术的关键创新在于,能够对来自同一镰状细胞病患者的血液样本,同步测量其中红细胞的物理特性及其在微小血管中的流动动力学行为。这使得研究者能够在同一个体系中关联微观细胞属性与宏观流动现象。
通过对患者样本的分析,研究获得了一个核心发现:尽管不同患者的血液组成复杂多变,但其整体血液的有效粘度主要可以由样本中“僵化”或变硬的红细胞所占的比例来解释。有趣的是,这种关系与物理世界中简单的刚性颗粒悬浮液所表现出的规律存在定性上的相似之处,尽管血液中的细胞在机械性质上远比均匀的刚性颗粒更为多样和复杂。
为了深入探究这种宏观流变特性背后的微观物理图景,研究者们将实验测量与计算机模拟相结合,并对流动中细胞的时空分布进行了高分辨率的观测。他们揭示了细胞如何通过自我组织来影响血流。研究发现在中等氧气水平下,较僵硬的红细胞会倾向于向血管壁迁移,即发生“边缘化”,这改变了流动的剖面。而在严重缺氧的条件下,由于红细胞浓度在空间分布上不均匀,局部区域会形成“堵塞”,类似于交通拥堵,显著阻碍了血液的顺畅流动。正是这些由细胞特性决定的、动态的时空组织结构,最终塑造了我们在疾病中观察到的异常血液流变行为。
这项研究首次明确地从悬浮物理学的框架出发,定义了镰状细胞病中病理血流动力学的多尺度物理基础。它不仅增进了我们对这一特定血液疾病的理解,其揭示的原理——异质颗粒如何通过自组织影响整体悬浮液的流动——也对更广泛的复杂流体研究具有启示意义。
本文由 天纳乾坤 编辑
扫描二维码查看源文
Science advances | Volume 12, Issue 1
10.1126/sciadv.adx3842
中国发表(34)
China
JPAD IF: 07.800Ahead of Print.No.01Identifying risk factors of young-onset dementia and evaluating evidence hierarchy: a meta-analysis and umbrella review年轻起病性痴呆风险因素的识别与证据等级评估:一项meta分析与伞状综述DOI: 10.1016/j.tjpad.2025.100467
Int J Biol Macromol IF: 08.500Ahead of Print.No.02Rbbp7-mediated deacetylation of Acsl4 promotes ovarian aging by enhancing ferroptosisRbbp7介导的Acsl4去乙酰化通过增强铁死亡促进卵巢衰老DOI: 10.1016/j.ijbiomac.2025.149976
World neurosurgery IF: 02.100Ahead of Print.No.03Correlation between spinal-pelvic parameters and ossification of the thoracolumbar ligamentum flavum: A cross-sectional study脊柱-骨盆参数与胸腰椎黄韧带骨化之间的相关性:一项横断面研究DOI: 10.1016/j.wneu.2025.124772
Neural networks IF: 06.300Ahead of Print.No.04FDAU-Net: An efficient optic disc segmentation network with flexible wavelet convolution block and selective dual-attention fusion gateFDAU-Net:一种集成了灵活小波卷积块与选择性双注意力融合门的高效视盘分割网络DOI: 10.1016/j.neunet.2025.108509
International immunopharmacology IF: 04.700Ahead of Print.No.05Paeoniflorin suppresses cardiomyocyte pyroptosis and ameliorates diabetic cardiomyopathy by AMPK/Nrf2/NLRP3 pathway芍药苷通过AMPK/Nrf2/NLRP3通路抑制心肌细胞焦亡并改善糖尿病心肌病DOI: 10.1016/j.intimp.2025.116122
Journal of nutrition IF: 03.800Ahead of Print.No.06Sialic Acid Supplementation in Perinatal Mice Attenuates Gestational Diabetes Mellitus-induced Liver Injury in Offspring at Early Adulthood围产期补充唾液酸可减轻妊娠期糖尿病诱导的子代成年早期肝损伤DOI: 10.1016/j.tjnut.2025.101292
JPAD IF: 07.800Ahead of Print.No.07The association of estimated glucose disposal rate with white matter hyperintensities: A large prospective cohort study估计葡萄糖利用率与脑白质高信号的关联性:一项大型前瞻性队列研究DOI: 10.1016/j.tjpad.2025.100464
International immunopharmacology IF: 04.700Ahead of Print.No.08Salidroside alleviates ethanol exposure-exacerbated hepatic insulin resistance in diabetic mice红景天苷改善乙醇暴露加剧的糖尿病小鼠肝脏胰岛素抵抗DOI: 10.1016/j.intimp.2025.116101
Journal of nutrition IF: 03.800Ahead of Print.No.09Effect of Vitamin D Supplementation on Metabolic Parameters in Patients with Metabolic Associated Fatty Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials维生素D补充对代谢相关脂肪肝病患者代谢参数的影响:随机对照试验的系统评价与荟萃分析DOI: 10.1016/j.tjnut.2025.101314
Journal of hazardous materials IF: 11.300Ahead of Print.No.10Long-term ozone exposure and risks of diabetes and hypertension: Mediated by inflammatory, lipid and oxidative stress biomarkers in a prospective cohort长期臭氧暴露与糖尿病及高血压风险:一项前瞻性队列中炎症、脂质和氧化应激生物标志物的介导作用DOI: 10.1016/j.jhazmat.2025.140989
Science advances IF: 12.500Volume 12, Issue 1No.11Galectin-3 exacerbates autoimmune diabetes by limiting regulatory T cell differentiation and functionGalectin-3通过限制调节性T细胞分化和功能加剧自身免疫性糖尿病DOI: 10.1126/sciadv.adz7916
J Agric Food Chem IF: 06.200Ahead of Print.No.12Advances in Chemically Modified Polysaccharides with Enhanced Hypoglycemic Bioactivity化学改性多糖降血糖生物活性增强研究进展DOI: 10.1021/acs.jafc.5c08511
Preventive medicine reports IF: 02.400Volume 61, Issue No.13Dietary intake and its relationship with physical growth and serum nutrient levels for preschool-aged children in southern China中国南方学龄前儿童膳食摄入及其与体格生长和血清营养素水平的关系DOI: 10.1016/j.pmedr.2025.103344
Frontiers in medicine IF: 03.000Volume 12, Issue No.14Case Report: Experience in the diagnosis and treatment of a male patient with plasma cell mastitis in the lump stage and review of the literature病例报告:肿块期男性浆细胞性乳腺炎患者的诊疗经验与文献回顾DOI: 10.3389/fmed.2025.1595042
Frontiers in neurology IF: 02.800Volume 16, Issue No.15Associations of body roundness index and body mass index with obstructive sleep apnea: evidence from two cohorts study体围指数与体质量指数与阻塞性睡眠呼吸暂停的关联:来自两项队列研究的证据DOI: 10.3389/fneur.2025.1709205
Frontiers in pharmacology IF: 04.800Volume 16, Issue No.16Recent advances in mineralocorticoid receptor antagonists for heart failure with preserved ejection fraction: focus on finerenone in the era of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonistsSGLT2抑制剂与GLP-1受体激动剂时代下非奈利酮在射血分数保留的心力衰竭中的应用进展DOI: 10.3389/fphar.2025.1725782
Frontiers in endocrinology IF: 04.600Volume 16, Issue No.17Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications多囊卵巢综合征中的脂肪-雄激素交互对话:机制与治疗启示DOI: 10.3389/fendo.2025.1731179
Frontiers in endocrinology IF: 04.600Volume 16, Issue No.18Efficacy and safety of insulin efsitora in type 2 diabetes: a meta-analysis of randomized controlled trials胰岛素Efsitora在2型糖尿病中的有效性和安全性:一项随机对照试验的荟萃分析DOI: 10.3389/fendo.2025.1608458
Diabetology international IF: 01.200Volume 17, Issue 1No.19Three-dimensional models for type 2 diabetes study用于2型糖尿病研究的三维模型DOI: 10.1007/s13340-025-00862-6
Biochem Biophys Rep IF: 02.200Volume 45, Issue No.20Comparative analysis of activation of macrophages/microglia in diabetic retinopathy and Familial Exudative Vitreoretinopathy糖尿病视网膜病变与家族性渗出性玻璃体视网膜病变中巨噬细胞/小胶质细胞激活的比较分析DOI: 10.1016/j.bbrep.2025.102396
Metabolism open IF: 02.700Volume 28, Issue No.21A lysosomal surveillance response promotes healthspan in C. elegans溶酶体监视反应促进秀丽隐杆线虫健康寿命DOI: 10.1016/j.metop.2025.100396
Metabolism open IF: 02.700Volume 28, Issue No.22The moderating role of vitamin E in the association between PFAS exposures and diabetes risk: Evidence from the NHANES 2017-2018维生素E在PFAS暴露与糖尿病风险关联中的调节作用:来自NHANES 2017-2018的证据DOI: 10.1016/j.metop.2025.100395
Heliyon IF: 03.600Volume 11, Issue 4No.23Enhancing placental pathology detection with GAMatrix-YOLOv8 model基于GAMatrix-YOLOv8模型提升胎盘病理检测效能DOI: 10.1016/j.heliyon.2025.e42441
Acta pharmaceutica sinica B IF: 14.600Volume 15, Issue 12No.24ROS-scavenging nanomaterials as emerging tools for bone tissue regeneration: A comprehensive review of recent progressROS清除纳米材料:骨组织再生的新兴工具与近期进展全面综述DOI: 10.1016/j.apsb.2025.09.040
Drug Des Devel Ther IF: 05.100Volume 19, Issue No.25SGLT2 Inhibitors in Combination Therapies for Tumors: A Novel Approach to Synergistic Treatment StrategiesSGLT2抑制剂在肿瘤联合疗法中的应用:一种协同治疗新策略DOI: 10.2147/DDDT.S556231
Iran J Pharm Res IF: 01.800Volume 24, Issue 1No.26Ellagic Acid Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis Through the Modulation of the SIRT1/p53 Pathway in Streptozotocin-Induced Diabetic Rats鞣花酸通过调控SIRT1/p53通路抑制铁死亡,改善链脲佐菌素诱导糖尿病大鼠的心肌病DOI: 10.5812/ijpr-166600
Risk Manag Healthc Policy IF: 02.000Volume 18, Issue No.27Remnant Cholesterol Inflammatory Index for Predicting Heart Failure Risk in Patients with Coronary Artery Disease and Type 2 Diabetes: A Retrospective Study Using Multiple Machine Learning Approaches残余胆固醇炎症指数预测冠心病合并2型糖尿病患者心力衰竭风险:一项基于多机器学习方法的回顾性研究DOI: 10.2147/RMHP.S566696
Int J Endocrinol IF: 02.300Volume 2025, Issue No.28Relationship Between Serum Osmolality and Diabetic Foot Ulcers in a US Population With Diabetes: Results From NHANES 1999-2004美国糖尿病患者血清渗透压与糖尿病足溃疡的关系:来自NHANES 1999-2004的结果DOI: 10.1155/ije/8820495
Int J Endocrinol IF: 02.300Volume 2025, Issue No.29Mechanism of Jianpixiaoke Recipe in Treating Type 2 Diabetes Based on Network Pharmacology and Molecular Docking基于网络药理学与分子对接探讨Jianpixiaoke Recipe治疗2型糖尿病的机制DOI: 10.1155/ije/4160656
Int J Endocrinol IF: 02.300Volume 2025, Issue No.30PTEN and GATA3 as Key Molecular Mediators Linking Diabetes Mellitus to Osteoarthritis: A Comprehensive Mendelian Randomization, Bioinformatics, and Experimental StudyPTEN与GATA3作为连接糖尿病与骨关节炎的关键分子介导者:一项综合性的孟德尔随机化、生物信息学及实验研究DOI: 10.1155/ije/2838739
Int J Endocrinol IF: 02.300Volume 2025, Issue No.31Exploratory Research on the Urine Proteome in Patients With Diabetic Peripheral Neuropathy糖尿病周围神经病变患者尿液蛋白质组的探索性研究DOI: 10.1155/ije/6652078
Frontiers in endocrinology IF: 04.600Volume 16, Issue No.32Diabetes as an independent risk factor for severe inflammatory bowel disease: evidence from an inflammation-metabolism-liver coupling framework糖尿病是重症炎症性肠病的独立危险因素:来自炎症-代谢-肝脏耦合框架的证据DOI: 10.3389/fendo.2025.1707507
Exploration (Beijing, China)Volume 5, Issue 6No.33Activating Ferroptosis of M1 Macrophages: A Novel Mechanism of Asiaticoside Encapsuled in GelMA for Anti-Inflammation in Diabetic Wounds激活M1巨噬细胞铁死亡:积雪草苷包裹于GelMA中抗糖尿病伤口炎症的新机制DOI: 10.1002/EXP.20240062
Int J Gynaecol Obstet IF: 02.400Ahead of Print.No.34Nonlinear association of triglyceride-glucose body mass index with all-cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey绝经后女性中甘油三酯-葡萄糖体重指数与全因死亡率的非线性关联:一项基于2001年至2014年美国国家健康与营养调查的回顾性队列研究DOI: 10.1002/ijgo.70778
其他发布内容(105)
More Published Articles
Adv Exp Med BiolVolume 1490, Issue No.01Study of the Genetic Basis of Childhood and Adolescent Obesity with Stress Through the Analysis of Multidimensional Data with Machine Learning and Artificial Intelligence Tools运用机器学习与人工智能工具分析多维数据,探究压力背景下儿童及青少年肥胖的遗传基础DOI: 10.1007/978-3-032-03402-1_36
Sub-cellular biochemistryVolume 114, Issue No.02Noncoding RNAs: A Novel Frontier in Liver Cancer Research and Therapy: Implications for Precision Oncology非编码RNA:肝癌研究与治疗的新前沿:对精准肿瘤学的启示DOI: 10.1007/978-3-032-08530-6_5
Adv Exp Med BiolVolume 1500, Issue No.03Maternal Caffeine Consumption and Pregnancy Outcomes孕妇咖啡因摄入与妊娠结局DOI: 10.1007/978-3-032-12741-9_10
Journal of nutrition IF: 03.800Ahead of Print.No.04LC-MS/MS-Based Targeted Lipidomic Analysis of Obesity-Related Colorectal Cancer: Potential Roles of the CYP Eicosanoid Pathway基于LC-MS/MS的靶向脂质组学分析揭示肥胖相关结直肠癌中CYP类花生酸通路的潜在作用DOI: 10.1016/j.tjnut.2025.101311
J Biol Chem IF: 03.900Ahead of Print.No.05O-GlcNAc Transferase Couples Nutrient Availability to Synaptic Plasticity in Paraventricular Neurons to Regulate SatietyO-GlcNAc转移酶通过耦联室旁核神经元营养可利用性与突触可塑性来调控饱腹感DOI: 10.1016/j.jbc.2025.111124
J Am Acad Dermatol IF: 11.800Ahead of Print.No.06Glucagon-Like Peptide-1 Receptor Agonists May Decrease Biologic Initiation in Hidradenitis Suppurativa: A TriNetX Retrospective Analysis胰高血糖素样肽-1受体激动剂可能减少化脓性汗腺炎中生物制剂的起始使用:一项TriNetX回顾性分析DOI: 10.1016/j.jaad.2025.12.092
Am J Clin Nutr IF: 06.900Ahead of Print.No.07Undernutrition or Obesity: Relationship with Long-Term Survival in Children with Acute Lymphoblastic Leukemia in an Upper-Middle Income Country. A multicenter cohort study营养不良还是肥胖:在中等偏上收入国家与儿童急性淋巴细胞白血病长期生存的关系——一项多中心队列研究DOI: 10.1016/j.ajcnut.2025.101180
Adv Exp Med BiolVolume 1490, Issue No.08Classification of Choroidal Neovascularization and Diabetic Macular Edema Based on Feature Extraction from Optical Coherence Tomography Images基于光学相干断层扫描图像特征提取的脉络膜新生血管与糖尿病性黄斑水肿分类DOI: 10.1007/978-3-032-03402-1_30
Adv Exp Med BiolVolume 1490, Issue No.09Cultural Adaptation and Psychometric Properties of the Greek Version of the Diabetes Attitude Scale (DAS-3)希腊版糖尿病态度量表(DAS-3)的文化调适与心理测量学特性DOI: 10.1007/978-3-032-03402-1_15
JPAD IF: 07.800Ahead of Print.No.10Associations of modifiable and non-modifiable risk factors with longitudinal white matter hyperintensities, amyloid-β and tau - a prospective cohort study可改变与非可改变风险因素与纵向白质高信号、β-淀粉样蛋白及tau蛋白关联性的前瞻性队列研究DOI: 10.1016/j.tjpad.2025.100448
JPAD IF: 07.800Ahead of Print.No.11Soluble and plaque amyloid associations with peripheral glucose dysregulation modulated by tau pathology in Alzheimer's disease阿尔茨海默病中可溶性及斑块淀粉样蛋白与周边血糖失调的关联受tau病理调节DOI: 10.1016/j.tjpad.2025.100459
British journal of anaesthesia IF: 09.200Ahead of Print.No.12Factors associated with admission before the day of elective major surgery: an analysis of data from the UK Perioperative Quality Improvement Programme英国择期大手术患者手术日前入院的相关因素分析:基于围手术期质量改进计划数据的分析DOI: 10.1016/j.bja.2025.10.064
HPB IF: 02.400Ahead of Print.No.13A systematic review of economic evaluation in pancreatic cystic neoplasms胰腺囊性肿瘤经济评价的系统综述DOI: 10.1016/j.hpb.2025.12.004
Canadian journal of diabetes IF: 02.600Ahead of Print.No.14Guided self-determination intervention supports person-centred reflections, self-insights and behavior changes among people with type 2 diabetes引导式自我决策干预支持2型糖尿病患者以人为中心的反思、自我认知和行为改变DOI: 10.1016/j.jcjd.2025.12.013
Journal of nutrition IF: 03.800Ahead of Print.No.15Toward Reproducible Metabolism Research: Consensus emerges on preclinical indirect calorimetry迈向可重复代谢研究:临床前间接测热法共识初现DOI: 10.1016/j.tjnut.2025.101308
Journal of nutrition IF: 03.800Ahead of Print.No.16Recent choline intake is inversely associated with inflammation in pregnancy- Evidence from the Canadian APrON cohort近期胆碱摄入量与妊娠期炎症呈负相关——来自加拿大APrON队列的证据DOI: 10.1016/j.tjnut.2025.101278
Pharmacological research IF: 10.500Ahead of Print.No.17IUPHAR Review: From Foe to Friend: Repurposing Glucagon to Treat Obesity and Type 2 DiabetesIUPHAR综述:从敌到友——重新利用胰高血糖素治疗肥胖症和2型糖尿病DOI: 10.1016/j.phrs.2025.108077
Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.18Global Leadership Initiative on Malnutrition-based nutritional phenotype and factors associated with the outcomes of hospitalized patients managed by a Nutrition Support Team: a retrospective study基于全球营养不良领导倡议的营养表型及其与营养支持团队管理的住院患者结局相关因素:一项回顾性研究DOI: 10.1016/j.clnesp.2025.102889
Behavioural brain research IF: 02.300Ahead of Print.No.19DEVELOPMENTAL DIFFERENCES IN REWARD-LEARNING AND ITS CONNECTION TO RESTING-STATE FUNCTIONAL CONNECTIVITY MODELED USING A HIERARCHICAL BAYESIAN MODEL基于分层贝叶斯模型研究的奖赏学习发育差异及其与静息态功能连接的关系DOI: 10.1016/j.bbr.2025.116008
Journal of pediatric urology IF: 01.900Ahead of Print.No.20Nomogram of fetal penile length during pregnancy: A systematic review妊娠期胎儿阴茎长度列线图:一项系统综述DOI: 10.1016/j.jpurol.2025.12.009
Colloids Surf B Biointerfaces IF: 05.600Ahead of Print.No.21Bioactive human placental ECM hydrogels crosslinked with tannic acid enhance stability and antioxidant properties for diabetic wound healing与单宁酸交联的生物活性人类胎盘ECM水凝胶增强稳定性和抗氧化性能用于糖尿病伤口愈合DOI: 10.1016/j.colsurfb.2025.115406
Journal of clinical neuroscience IF: 01.800Ahead of Print.No.22Post-stroke seizures in malignant middle cerebral artery infarction treated with decompressive hemicraniectomy: A meta-analysis of predictive factors and clinical outcomes去骨瓣减压术治疗恶性大脑中动脉梗死后癫痫发作:预测因素与临床结局的荟萃分析DOI: 10.1016/j.jocn.2025.111835
Reproductive Biology IF: 02.000Ahead of Print.No.23The secretome from human amniotic membrane-derived mesenchymal stem cells alleviate oxidative damage in bovine sperm人羊膜来源间充质干细胞分泌组缓解牛精子氧化损伤DOI: 10.1016/j.repbio.2025.101178
Tissue & cell IF: 02.500Ahead of Print.No.24Fibrin hydrogel incorporated with microspheres containing vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) accelerated the healing of diabetic wounds in rats含有血管内皮生长因子(VEGF)和碱性成纤维细胞生长因子(bFGF)微球的纤维蛋白水凝胶加速了大鼠糖尿病伤口的愈合DOI: 10.1016/j.tice.2025.103301
Biophysical chemistry IF: 02.200Ahead of Print.No.25Modulation of islet amyloid polypeptide induced β-cell toxicity and amyloid formation by serum albumin proteins血清白蛋白蛋白对胰岛淀粉样多肽诱导的β细胞毒性及淀粉样蛋白形成的调节作用DOI: 10.1016/j.bpc.2025.107565
Am J Ophthalmol IF: 04.200Ahead of Print.No.26Reply to Comment on Glucagon-like Peptide-1 Receptor Agonist Use and Risk of Cataract Development关于胰高血糖素样肽-1受体激动剂使用与白内障发生风险的回应DOI: 10.1016/j.ajo.2025.12.021
Journal of Stroke IF: 08.600Ahead of Print.No.27RNF213 p.R4810K Variant and Intracranial Atherosclerosis: Increased Risk in Obese Variant CarriersRNF213 p.R4810K 变异与颅内动脉粥样硬化:肥胖变异携带者风险增加DOI: 10.5853/jos.2025.02607
Adv Exp Med BiolVolume 1490, Issue No.28Investigation of Anxiety, Stress, Depression, and Quality of Life of Pregnant Women with Gestational Diabetes Mellitus (GDM)妊娠期糖尿病(GDM)孕妇的焦虑、压力、抑郁与生活质量调查DOI: 10.1007/978-3-032-03402-1_19
Metabolism IF: 11.900Ahead of Print.No.29Incretin-based therapy and atrial fibrillation risk in overweight or obesity肠促胰岛素类治疗与超重或肥胖患者心房颤动风险DOI: 10.1016/j.metabol.2025.156491
Am J Clin Nutr IF: 06.900Ahead of Print.No.30Prognostic value of adiposity indices in anticoagulated patients with atrial fibrillation: The prospective Murcia AF Project III cohort肥胖指数对抗凝治疗心房颤动患者预后的预测价值:前瞻性 Murcia AF Project III 队列研究DOI: 10.1016/j.ajcnut.2025.101184
Adv Exp Med BiolVolume 1490, Issue No.31Teachers' Knowledge, Attitudes, and Sense of Self-Efficacy Toward Students with Type 1 Diabetes Mellitus (Insulin-Dependent) in Primary Education小学教师对1型糖尿病(胰岛素依赖型)学生的知识、态度及自我效能感DOI: 10.1007/978-3-032-03402-1_33
Methods in molecular biologyVolume 3007, Issue No.32Expression, Purification, and Functional Analysis Methods of Antigen-Processing Aminopeptidases ERAP1, ERAP2, and IRAP抗原加工氨基肽酶ERAP1、ERAP2与IRAP的表达、纯化及功能分析方法DOI: 10.1007/978-1-0716-5092-9_9
J Pharmacol Exp Ther IF: 03.800Volume 392, Issue 12No.33mRNA and gene therapy for diabetes: The next-generation treatment frontiers糖尿病mRNA与基因疗法:下一代治疗前沿DOI: 10.1016/j.jpet.2025.103706
Journal of nutrition IF: 03.800Ahead of Print.No.34Time-Restricted Eating in Metabolic and Clinical Health: A Current Evidence and Mechanistic Insights限时饮食在代谢与临床健康中的应用:现有证据与机制解析DOI: 10.1016/j.tjnut.2025.101269
Journal of nutrition IF: 03.800Ahead of Print.No.35Bioconverted red ginseng protects liver functions and alters insulin homeostasis-associated gut microbiome composition in aged mice生物转化红参在老年小鼠中保护肝脏功能并改变胰岛素稳态相关肠道菌群组成DOI: 10.1016/j.tjnut.2025.101310
Immunology letters IF: 02.800Ahead of Print.No.36Design and Application of a Multi-Epitope ACE2 Antigen for Detection of Autoantibodies in Post-COVID-19 Diagnosed Type 1 Diabetes多表位ACE2抗原的设计与应用用于检测COVID-19后诊断的1型糖尿病自身抗体DOI: 10.1016/j.imlet.2025.107127
Brain, behavior, and immunity IF: 07.600Ahead of Print.No.37Acute peripheral versus central inhibition of insulin receptors differentially alters cytokine and blood-brain barrier responses to an inflammatory stimulus急性外周与中枢胰岛素受体抑制对炎症刺激的细胞因子及血脑屏障反应具有不同影响DOI: 10.1016/j.bbi.2025.106251
J Pharm Sci IF: 03.800Ahead of Print.No.38Preparation and characterization of oral insulin-trimethyl chitosan complex-loaded solid self-nanoemulsifying drug delivery systems (SNEDDS)口服胰岛素-三甲基壳聚糖复合物负载的固体自纳米乳化给药系统的制备与表征DOI: 10.1016/j.xphs.2025.104149
Am J Emerg Med IF: 02.200Ahead of Print.No.39Comparison of Single-Dose Intravenous Insulin Regular vs. Insulin Lispro for Hyperkalemia Treatment in the Emergency Department: The SIR-LISPRO Trial单剂量静脉胰岛素常规与胰岛素赖脯用于急诊科高钾血症治疗的比较:SIR-LISPRO试验DOI: 10.1016/j.ajem.2025.12.031
Archives of oral biology IF: 02.100Ahead of Print.No.40Insulin-like growth factor-binding protein 3 regulates collagen production via TGF-β-Smad2/3 pathway and osteogenic differentiation related with phosphorylation of Akt in human periodontal ligament-derived cell line胰岛素样生长因子结合蛋白3通过TGF-β-Smad2/3通路调节胶原蛋白生成和与Akt磷酸化相关的成骨分化DOI: 10.1016/j.archoralbio.2025.106483
J Plast Reconstr Aesthet Surg IF: 02.400Ahead of Print.No.41The impact of metabolic syndrome on postoperative outcomes in breast oncoplastic surgery: A nationwide analysis代谢综合征对乳腺肿瘤整形手术术后结果的影响:一项全国性分析DOI: 10.1016/j.bjps.2025.12.007
Ophthalmic genetics IF: 01.000Ahead of Print.No.42Analysis of the impact of VEGF gene variants rs699947, rs833061, and rs3025039 on diabetic retinopathy in a case-control study一项病例对照研究中VEGF基因变异rs699947、rs833061和rs3025039对糖尿病视网膜病变的影响分析DOI: 10.1080/13816810.2025.2609678
Endocrine practice IF: 04.600Ahead of Print.No.43Remote Patient Monitoring with Continuous Glucose Monitoring Improves Glycemic Outcomes in Patients with Type 2 Diabetes at a Safety-Net Hospital远程患者监测结合连续血糖监测改善安全网医院2型糖尿病患者血糖结局DOI: 10.1016/j.eprac.2025.12.016
Nutrition research IF: 03.100Ahead of Print.No.44Beneficial effects of time-restricted eating on some cardiometabolic factors and anthropometric measures in adults with type 2 diabetes: an umbrella meta-analysis of meta-analyses of randomized controlled trials时间限制饮食对成人2型糖尿病患者部分心脏代谢因素及人体测量指标的有益影响:一项随机对照试验的伞状Meta分析DOI: 10.1016/j.nutres.2025.12.002
Adv GerontolVolume 38, Issue 4No.45[Inflamaging in elderly patients with sarcopenic obesity.]老年肌肉减少性肥胖患者的炎性衰老https://pubmed.ncbi.nlm.nih.gov/41477774
Diabetes & metabolic syndrome IF: 03.400Ahead of Print.No.46Diabetes with low body mass index in India: A secondary analysis of NFHS-5 data印度低体重指数糖尿病的患病率:基于NFHS-5数据的二次分析DOI: 10.1016/j.dsx.2025.103371
Diabetes & metabolic syndrome IF: 03.400Ahead of Print.No.47Association of sodium-glucose cotransporter 2 inhibitors with the risk of incident anxiety and insomnia: a retrospective cohort study using the TriNetX database钠-葡萄糖协同转运蛋白2抑制剂与新发焦虑和失眠风险的关联:一项基于TriNetX数据库的回顾性队列研究DOI: 10.1016/j.dsx.2025.103373
Occup Ther Health Care IF: 01.000Ahead of Print.No.48A Brief Occupational Therapy Foot Care Program for Community-Dwelling Older Adults and the Social Connectedness Implications一项针对社区居住老年人的简短作业治疗足部护理项目及其社会连结意义DOI: 10.1080/07380577.2025.2609716
Cell reports IF: 06.900Ahead of Print.No.49Longevity of cardiac and skeletal muscle proteins is dependent on tissue and subcellular compartmentation patterns心肌与骨骼肌蛋白寿命取决于组织与亚细胞区室化模式DOI: 10.1016/j.celrep.2025.116768
Adv GerontolVolume 38, Issue 4No.50[Automated system for personalization of therapeutic management tactics for comorbid elderly patients with type 2 diabetes mellitus.]老年共病2型糖尿病患者治疗管理策略个性化自动化系统https://pubmed.ncbi.nlm.nih.gov/41477775
Adv GerontolVolume 38, Issue 4No.51[Vascular dysfunction: processes due to aging, approaches to restorative therapy and prevention (part 1).]血管功能障碍:衰老相关机制、修复治疗与预防策略(第一部分)https://pubmed.ncbi.nlm.nih.gov/41477787
Adv GerontolVolume 38, Issue 4No.52[Cognitive impairments in metabolic syndrome.]代谢综合征中的认知障碍https://pubmed.ncbi.nlm.nih.gov/41477773
Adv GerontolVolume 38, Issue 4No.53[Effect of semaglutide treatment on the body weight and the glucose, insulin and thyroid hormone levels in aging rats with diet-induced obesity.]司美格鲁肽对饮食诱导肥胖老龄大鼠的体重及血糖、胰岛素、甲状腺激素水平的影响https://pubmed.ncbi.nlm.nih.gov/41477783
Acta Obstet Gynecol Scand IF: 03.100Ahead of Print.No.54Impact of episiotomy on anal incontinence following second- to fourth-degree perineal tears-A cohort study会阴切开术对二至四度会阴撕裂后肛门失禁的影响——一项队列研究DOI: 10.1111/aogs.70124
Nordic journal of psychiatry IF: 01.500Ahead of Print.No.55Substance use disorders and use of somatic health services among forensic psychiatric patients: a nationwide register-based cohort study物质使用障碍与法医精神病患者躯体健康服务使用情况:一项全国性登记数据队列研究DOI: 10.1080/08039488.2025.2610199
Islets IF: 01.700Volume 18, Issue 1No.56Differential expression of mitomiRs in pancreatic islet cells associated with maternal protein restriction母体蛋白限制相关胰腺胰岛细胞中mitomiRs的差异表达DOI: 10.1080/19382014.2025.2610590
Eur J Public Health IF: 03.900Ahead of Print.No.57Declining 28-day population myocardial infarction case-fatality trends in Catalonia, Spain: an analysis of the possible contribution of emergency management network西班牙加泰罗尼亚地区28天人群心肌梗死病例死亡率下降趋势:一项对急诊管理网络可能贡献的分析DOI: 10.1093/eurpub/ckaf203
Anesthesiology and pain medicineVolume 15, Issue 6No.58The Effect of Pregabalin-Paracetamol on Shoulder Pain in Patients Following Laparoscopic Cholecystectomy: A Randomized Clinical Trial普瑞巴林-扑热息痛对腹腔镜胆囊切除术后患者肩痛的影响:一项随机临床试验DOI: 10.5812/aapm-149328
Clinical case reports IF: 00.600Volume 14, Issue 1No.59Beyond Oral Pain: A Unique Case of Burning Mouth Syndrome With Coexisting Vulvodynia and Cognitive Impairment in a Postmenopausal Woman超越口腔疼痛:一位绝经后女性灼口综合征合并外阴痛与认知障碍的独特病例DOI: 10.1002/ccr3.71485
BMJ public healthVolume 3, Issue 2No.60Understanding the epidemiology of TB-HIV co-infection in Indonesia: evidence from the 2023 national TB registry理解印度尼西亚结核病-艾滋病合并感染的流行病学:来自2023年国家结核病登记处的证据DOI: 10.1136/bmjph-2025-003585
Am J Geriatr Psychiatry Open Sci Educ PractVolume 8, Issue No.61Bidirectional Associations Between Obesity and Depressive Symptoms: Results From the Multiethnic Postmenopausal Cohort of the Women's Health Initiative Study肥胖与抑郁症状在绝经后女性中的双向关联:基于“女性健康倡议”研究多种族绝经后队列的结果DOI: 10.1016/j.osep.2025.10.002
Int J Anal Chem IF: 01.700Volume 2025, Issue No.62Standardization of Fecal Metabolomics Using Microbiome Preservation Kits: Implications for Multiomics Integration使用微生物组保存试剂盒实现粪便代谢组学标准化:对多组学整合的意义DOI: 10.1155/ianc/8551545
Frontiers in nutrition IF: 05.100Volume 12, Issue No.63Supermarket nutritionists' perspectives, views, and experiences on affordability interventions to support healthier and more environmentally sustainable food purchasing in UK retail settings英国超市营养师对支持零售环境中更健康、更环保食品购买的负担能力干预措施的看法、观点和经验DOI: 10.3389/fnut.2025.1710661
Health science reports IF: 02.100Volume 9, Issue 1No.64Body Mass Analysis for Patients Undergoing Surgical Intervention: A Cross-Sectional Study接受手术干预患者的体质量分析:一项横断面研究DOI: 10.1002/hsr2.71707
Qatar medical journalVolume 2025, Issue 4No.65Obesity and cholesterol: A cross-sectional analysis of Qatar Biobank data肥胖与胆固醇:一项基于卡塔尔生物样本库数据的横断面研究DOI: 10.5339/qmj.2025.97
World J Otorhinolaryngol Head Neck Surg IF: 01.400Volume 11, Issue 4No.66Laryngopharyngeal Reflux: The Impact of Obesity喉咽反流:肥胖的影响DOI: 10.1002/wjo2.70010
Arch Rehabil Res Clin Transl IF: 02.000Volume 7, Issue 4No.67Feasibility of a Preoperative Exercise and Nutritional Intervention in Sarcopenic Obese Individuals Undergoing Hip or Knee Arthroplasty: A Pilot Randomized Controlled Trial术前运动与营养干预在肌少性肥胖患者髋膝关节置换术中的可行性:一项试点随机对照试验DOI: 10.1016/j.arrct.2025.100524
Food science & nutrition IF: 03.800Volume 14, Issue 1No.68Salt Intake Among the Iranian Population and Public Attitudes Toward Salt Consumption: National and Subnational Report From STEPS 2021伊朗人群盐摄入量与公众对食盐消费的态度:来自STEPS 2021的国家及省级报告DOI: 10.1002/fsn3.71399
Metabolism open IF: 02.700Volume 28, Issue No.69Corrigendum to "Prevalence of normal weight obesity among adults in Southeast Asia: Insights from a systematic review and meta-analysis" [Metabol. Open 28C (2025) 100416]关于“东南亚成年人体重正常型肥胖患病率:系统综述和荟萃分析带来的启示”的更正DOI: 10.1016/j.metop.2025.100425
Curēus IF: 01.300Volume 17, Issue 12No.70Exploring the Theoretical Potential of Benzphetamine in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)探索苯非他明治疗注意缺陷/多动障碍(ADHD)的理论潜力DOI: 10.7759/cureus.100363
Am J Sports Med IF: 04.500Volume 54, Issue 1No.71Obese Patients Treated by Hip Arthroscopy for Femoroacetabular Impingement Syndrome - 10-Year Functional Outcomes and Conversion Rates to Arthroplasty Compared With Normal-Weight Patients肥胖患者接受髋关节镜治疗股骨髋臼撞击综合征:与正常体重患者相比的10年功能结局及关节置换转化率DOI: 10.1177/03635465251392585
Int J Chron Obstruct Pulmon Dis IF: 03.100Volume 20, Issue No.72Association of Obesity with Symptoms and Quality of Life in COPD: Results from COSYCONETCOSYCONET研究揭示:肥胖与COPD患者的症状及生活质量相关DOI: 10.2147/COPD.S542628
Anemia IF: 02.600Volume 2025, Issue No.73Pregnancy Outcomes in Women With Thalassemia Trait: A Multicenter Cohort Study地中海贫血特征女性的妊娠结局:一项多中心队列研究DOI: 10.1155/anem/8899690
J Obstet Gynaecol India IF: 00.600Volume 75, Issue 6No.74Burden of Obesity in Nullipara with Singleton Pregnancy and Feto-Maternal Outcomes: A Retrospective Cohort Study From South India印度南部初产单胎妊娠女性的肥胖负担与母婴结局:一项回顾性队列研究DOI: 10.1007/s13224-025-02197-3
Frontiers in endocrinology IF: 04.600Volume 16, Issue No.75Case Report: Generalized lipodystrophy following immune-checkpoint inhibitor therapy病例报告:免疫检查点抑制剂治疗后出现的全身性脂肪营养不良DOI: 10.3389/fendo.2025.1710985
Frontiers in endocrinology IF: 04.600Volume 16, Issue No.76Telehealth insulin titration in adults with diabetes: a randomized controlled trial comparing bluetooth-enabled versus traditional glucometers成人糖尿病患者的远程胰岛素剂量调整:一项比较蓝牙血糖仪与传统血糖仪的随机对照试验DOI: 10.3389/fendo.2025.1724811
Diabetology international IF: 01.200Volume 17, Issue 1No.77Insulin edema in slowly progressive type 1 diabetes: improvement following adjustment of insulin therapy缓慢进展型1型糖尿病患者出现胰岛素水肿:调整胰岛素方案后改善DOI: 10.1007/s13340-025-00864-4
Curēus IF: 01.300Volume 17, Issue 12No.78Physical Activity as an Intervention for Frailty Syndrome: A Narrative Review体力活动作为衰弱综合征的干预措施:一项叙述性综述DOI: 10.7759/cureus.100293
Curēus IF: 01.300Volume 17, Issue 11No.79The Effects of Sodium-Glucose Co-transporter 2 Inhibitors on Cardiovascular Outcomes in Heart Failure: A Systematic Review and Meta-Analysis钠-葡萄糖协同转运蛋白2抑制剂对心力衰竭患者心血管结局的影响:一项系统综述与荟萃分析DOI: 10.7759/cureus.98140
Int J Pediatr IF: 01.300Volume 2025, Issue No.80Carbohydrate Counting as a Precision Method for Glycemic Control in Youth With Type 1 Diabetes: A Systematic Review and Meta-Analysis碳水化合物计数作为1型糖尿病青少年血糖控制的精准方法:一项系统评价与元分析DOI: 10.1155/ijpe/5532465
Open respiratory archivesVolume 8, Issue 1No.81Impact of Sleep-disordered Breathing Management in Primary Care on Systemic Hypertension Control: Protocol for the METASLEEP Implementation Trial睡眠呼吸障碍在基层医疗中的管理对系统性高血压控制的影响:METASLEEP实施试验方案DOI: 10.1016/j.opresp.2025.100522
Arthroplasty today IF: 02.100Volume 36, Issue No.82Clarifying Potential Candidates for Extended Oral Antibiotic Prophylaxis: A Retrospective Analysis of Risk Factors for Infection Following Revision Hip and Knee Arthroplasty明确延长口服抗生素预防的潜在适用人群:一项关于髋膝关节翻修术后感染危险因素的回顾性分析DOI: 10.1016/j.artd.2025.101866
Frontiers in digital health IF: 03.800Volume 7, Issue No.83FAIR foundations of a novel indicator vault for non-communicable diseases in the European Union: feasibility study for effective contextualisation of indicators欧盟非传染性疾病新型指标库的FAIR基础:面向指标有效情境化的可行性研究DOI: 10.3389/fdgth.2025.1685733
Open research EuropeVolume 4, Issue No.84Unmasking metabolic disruptors: The NEMESIS project's quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies揭开代谢干扰物的面纱:NEMESIS项目对新生物标志物、不良效应证据及高效方法的探索之旅DOI: 10.12688/openreseurope.18439.2
JCEM case reportsVolume 4, Issue 1No.85An Unusual Presentation of Severe Hypothyroidism in a Child With Undiagnosed Systemic Lupus Erythematous一例未确诊系统性红斑狼疮患儿出现严重甲状腺功能减退的异常表现DOI: 10.1210/jcemcr/luaf309
Curēus IF: 01.300Volume 17, Issue 11No.86Thyrotoxic Encephalopathy With Seronegative Thyroiditis: An Unusual Occurrence血清阴性甲状腺炎伴甲状腺毒症脑病:一例不寻常的病例DOI: 10.7759/cureus.98129
Curēus IF: 01.300Volume 17, Issue 11No.87Complications Following Lingual Tonsillectomy: Analysis of the National Surgical Quality Improvement Program (NSQIP) Database舌扁桃体切除术后并发症:全国外科质量改进计划(NSQIP)数据库分析DOI: 10.7759/cureus.98169
Curēus IF: 01.300Volume 17, Issue 11No.88Differentiating Taste Perception Between Pre-diabetes and Type 2 Diabetes: A Comparative Analysis糖尿病前期与2型糖尿病患者味觉感知差异比较分析DOI: 10.7759/cureus.98045
Journal of pharmacopuncture IF: 01.800Volume 28, Issue 4No.89Bee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications蜂产品与传统植物疗法用于伤口护理:科学证据与临床应用的全面综述DOI: 10.3831/KPI.2025.28.4.255
Frontiers in public health IF: 03.400Volume 13, Issue No.90Occupational and lifestyle risk factors associated with metabolic fatty liver disease among university staff in Indonesia印度尼西亚大学员工代谢相关脂肪肝病的职业和生活方式风险因素DOI: 10.3389/fpubh.2025.1739931
Ther Adv Infect Dis IF: 03.400Volume 12, Issue No.91Chronic pulmonary aspergillosis complicating pulmonary cystic echinococcosis: a global systematic review慢性肺曲霉病合并肺囊型包虫病:一项全球系统综述DOI: 10.1177/20499361251404362
Frontiers in microbiology IF: 04.500Volume 16, Issue No.92Expression of hemerythrin-like genes from the obligate aerobe Myxococcus xanthus improves the growth of the industrially relevant Gluconobacter oxydans来自严格需氧菌Myxococcus xanthus的血蓝蛋白样基因表达改善了工业相关菌Gluconobacter oxydans的生长DOI: 10.3389/fmicb.2025.1734440
Qatar medical journalVolume 2025, Issue 4No.93Remission of hypothyroidism in post-bariatric surgery patients减重手术后患者的甲状腺功能减退缓解情况DOI: 10.5339/qmj.2025.102
Qatar medical journalVolume 2025, Issue 4No.94Risk factors associated with hearing loss in neonates: A retrospective cross-sectional study from Qatar卡塔尔新生儿听力损失相关风险因素:一项回顾性横断面研究DOI: 10.5339/qmj.2025.99
Iran J Pharm Res IF: 01.800Volume 24, Issue 1No.95Short-term Antihyperglycemic and Weight Modulation Effects of Leuenbergeria bleo (Kunth) Lodé: Phytochemical Screening and in vivo Assessment in an Alloxan-Induced Diabetic Rat ModelLeuenbergeria bleo (Kunth) Lodé的短期抗高血糖及体重调节作用:植物化学成分筛选及在四氧嘧啶诱导糖尿病大鼠模型中的体内评估DOI: 10.5812/ijpr-164873
Frontiers in immunology IF: 05.900Volume 16, Issue No.96Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity巨噬细胞:自身免疫病中交感神经-免疫相互作用的核心介导者DOI: 10.3389/fimmu.2025.1654382
Front Cell Dev Biol IF: 04.300Volume 13, Issue No.97Microglia response and function in a chronic model of photoreceptor damage慢性光感受器损伤模型中的小胶质细胞应答与功能DOI: 10.3389/fcell.2025.1699271
Frontiers in oncology IF: 03.300Volume 15, Issue No.98What can claims data tell us about risk factors and survival of patients with hepatocellular carcinoma? Insights from a German population-based study索赔数据揭示肝细胞癌患者的风险因素与生存状况:来自德国一项基于人群的研究的启示DOI: 10.3389/fonc.2025.1650982
Obesity science & practice IF: 01.900Volume 12, Issue 1No.99Framing Obesity: The Role of the Research System in Perpetuating or Challenging Weight Stigma构建肥胖议题:研究体系在延续或挑战体重污名中的角色DOI: 10.1002/osp4.70111
Int J Gynaecol Obstet IF: 02.400Ahead of Print.No.100Impact of gestational weight gain on perineal injury and obstetric anal sphincter injury among underweight primiparous women妊娠期增重对低体重初产妇会阴损伤和产科肛门括约肌损伤的影响DOI: 10.1002/ijgo.70788
Front Clin Diabetes Healthc IF: 02.200Volume 6, Issue No.101Real-world effectiveness and safety of imeglimin: a single-center retrospective cohort study in Japan伊美格列明在真实世界中的有效性与安全性:一项日本的单中心回顾性队列研究DOI: 10.3389/fcdhc.2025.1694522
Food science & nutrition IF: 03.800Volume 14, Issue 1No.102Glucose-Lowering Properties of a Tea Formulation Containing Citrullus lanatus Peel, Ananas comosus Peel, and Mentha spicata L. Leaf Extracts in Dexamethasone-Induced Insulin-Resistant Wistar Rats一种含西瓜皮、菠萝皮和留兰香薄荷叶提取物的复方茶在地塞米松诱导的胰岛素抵抗Wistar大鼠中的降糖特性研究DOI: 10.1002/fsn3.71368
Lung cancer IF: 03.300Volume 16, Issue No.103Incretin Receptor Agonist, Semaglutide, as a Treatment for Alectinib-Induced Excessive Weight Gain. A Case Report肠促胰素受体激动剂司美格鲁肽治疗阿来替尼所致过度体重增加:一例病例报告DOI: 10.2147/LCTT.S549011
Diabetology international IF: 01.200Volume 17, Issue 1No.104Concurrent diabetes and heart failure: revisiting epidemiological and clinicopathological interplay糖尿病与心力衰竭并存:重审流行病学与临床病理的相互作用DOI: 10.1007/s13340-025-00855-5
Arch Rehabil Res Clin Transl IF: 02.000Volume 7, Issue 4No.105Screening, Diagnosis, and Treatment of Cardiometabolic Risk in Persons With Spinal Cord Injury/Disease: A Scoping Review脊髓损伤/疾病患者心血管代谢风险的筛查、诊断与治疗:范围综述DOI: 10.1016/j.arrct.2025.100543
100
Diabetes Mellitus(DM)
糖尿病
45
Obesity
肥胖症
29
Insulin
胰岛素
12
Type 2 diabetes mellitus(T2DM)
2型糖尿病
5
Hypoglycemic Agents
降糖药
5
Gestational Diabetes Mellitus(GDM)
妊娠糖尿病
5
Glucagon-Like Peptide-1 Receptor Agonists(GLP-1RA)
胰高血糖素样肽-1受体激动剂
4
Semaglutide
司美格鲁肽
4
Type 1 diabetes mellitus(T1DM)
1型糖尿病
4
Metformin
二甲双胍
4
Diabetic Retinopathy
糖尿病视网膜病
3
Metabolic Syndrome
代谢综合征
2
Sodium-Glucose Transporter 2 Inhibitors(SGLT-2i)
钠-葡萄糖协同转运蛋白2抑制剂
2
Dapagliflozin
达格列净
2
Empagliflozin
恩格列净
2
Diabetic Cardiomyopathies
糖尿病心肌病
2
Diabetic Foot
糖尿病足
2
Pregabalin
普瑞巴林
1
Canagliflozin
卡格列净
1
Dipeptidyl-Peptidase IV Inhibitors(DPP-4i)
二肽基肽酶-4抑制剂
编辑:天纳乾坤
审校:天纳乾坤