The researchers found that in 10 of 13 OACs, GLP-1 RAs compared with insulin were associated with a significant risk reduction including in gallbladder cancer, meningioma, pancreatic cancer, hepatocellular carcinoma, ovarian cancer, colorectal cancer, multiple myeloma, esophageal cancer, endometrial cancer, and kidney cancer (hazard ratios, 0.35, 0.37, 0.41, 0.47, 0.52, 0.54, 0.59, 0.60, 0.74, and 0.76, respectively). The hazard ratio for stomach cancer was "The potential cancer-preventative effects of OACs by GLP-1 RAs warrant further long-term studies as well as studies of individual newer and possibly more effective antidiabetic and weight loss agents as well as those with multihormone agonist activities," the authors write. Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.