Objective To study the effects of ropivacaine and bupivacaine combined spinal-epidural anesthesia (CSEA) on the hemodynamics of pregnant women receiving cesarean. Methods 140 puerperants receiving cesarean section were selected as research objects and randomly divided into observation group and control group with 70 cases in each group. The observation group received ropivacaine spinal-epidural anesthesia, while the control group received bupivacaine spinal-epidural anesthesia. Comparison was made in the hemodynamics, sensory and motor block, and adverse reactions between the two groups. Results Hemodynamics: five minutes after the administration, during the operation, and at the end of the operation, there were no significant differences in the MAP and SaO2 between the two groups (P>0.05). During the operation and at the end of the operation, the HR in the groups were significantly lower than those before the administration (P<0.05), but that of the observation group was significantly higher than that in the control group (P<0.05). Anesthesia quality: In the observation group, the sensory block onset time, the time of sensory block reaching the highest plane, sensory block duration, motor block onset time, and the motor block maximum time were significantly longer than those in the control group, while the motor block recovery time was significantly shorter than that in the latter group (P<0.05). Adverse reactions: the incidence of nausea and vomiting, blood pressure decreasing, bradycardia, and breathing difficulties in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Ropivacaine combined spinel-epidural anesthesia could help to stabilize the hemodynamics of puerperants receiving caesarean and cause less adverse reactions and faster recovery.