Herein, a novel pH-responsive adsorbent with selective adsorption effect on cationic and anionic dyes was further designed and prepared via radiation grafting in situ growth technique.The cheap, modifiable and benign natural renewable biomass loofah (LFs) was selected as the substrate, and then acrylic acid (AAc) was grafted onto the loofah substrate through electron beam (EB) radiation (grafting rate of 30.5 %).The introduction of -COOH effectively captured and fixed cobalt ions (Co²⁺), and zeolitic imidazolate framework-67 (ZIF-67) was grown in situ on the loofah surface with Co²⁺ as a metal center and 2-methylimidazole as the ligand, so a functional loofah-based adsorbent ZIF-67@LFs-AAc was obtained.The introduction of ZIF-67 significantly enhanced the adsorption efficiency and capability of biomass materials, and successfully combined the advantages of biomass and inorganic nanomaterials.The biosorbent is pH-responsive and can specifically adsorb anionic dyes in acidic setting.The equilibrium uptake capacity of Congo red (CR) is 433.9 mg/g at pH = 3.Cationic dyes can be selectively adsorbed under neutral and basic conditions, and the equilibrium uptake capacity of methylene blue (MB) is as high as 554.0 mg/g at pH = 7.When the addition of the ZIF-67@LFs-AAc was 1.0 g/L, the removed rates of MB and CR were 95.9 % and 91.8 %, resp.With ZIF-67@LFs-AAc, the adsorption of dyes is promoted by electrostatic interaction, pore adsorption, π-π interaction and hydrogen bond.In summary, the integration of MOFs with loofah can lead to the development of a highly efficient biosorbent for treating dye-containing wastewater, thereby offering promising prospects for its application in water treatment.

2025-01-01·Journal of Molecular Structure

Bioimaging research of a turn-on homodimer fluorescent probes for pH and viscosity: A new turn-on strategy

作者: Gao, Tao ; Zhang, Lu ; Xiang, Lingli ; Zhen, Yali ; Sang, Yanan ; Chen, Tao ; Dan, Liangfeng ; Xiang, Yu ; Yan, Ke ; Du, Linli ; Ning, Xiaojun ; Wang, Wei ; Yuan, Bin ; Min, Shuang

A turn-on homodimer fluorescent probe (BL) that responded to pH and viscosity was facilely synthesized based on homo-FRET.The probe exhibited strong fluorescence intensity and color changes in alk. pH.In addition, the probe′s fluorescence had altered with changes in viscosity.What′s more, Mitochondrial localization and pH bioimaging in E. coli cell experiments confirmed that BL was a novel multifunctional probe that could be applied to mitochondrial-targeted fluorescence imaging under normal conditions and real-time fluorescence imaging of E. coli under alk. conditions.

2024-12-31·All Life

Ferroptosis plays a role in osteoarthritis

作者: Tao, Xu ; Altahla, Ruba ; Alshorman, Jamal

In recent years, ferroptosis has been identified as a novel type of regulated cell death.As a cell death process, it differs from other processes like necrosis and apoptosis in the expression of morphol., biochem., and genetics.Ferroptosis provides a new view of programmed cell death.It is initiated by the oxidation of lipids, reactive oxygen species (ROS) formation and iron buildup within cells, leading to their demise.The identification of these biochem. events triggering ferroptosis has expanded understanding of controlled cellular suicide.A significant role of ferroptosis in osteoarthritis (OA) has been reported in recent studies.Both OA and ferroptosis exhibit anomalies in metabolism of iron, oxidation of lipids, and mitochondrial dysfunction.Nonetheless, our understanding of the specific genes involved in regulating ferroptosis in the context of OA is currently limited.Expanding our knowledge in this area could have profound implications for effectively managing and treating OA.This review offers an in-depth exploration of the mol. processes associated with ferroptosis.Furthermore, we discuss the roles of ferrioptosis in different aspects of osteoarthritis, encompassing the degradation of cartilage, synovitis, dysfunction of chondrocytes, and the manifestation of OA-related pain.We highlight the potential of targeting ferroptosis for OA treatment.

项与湖北科技学院相关的新闻（医药）

2023-07-02

·蒲公英Ouryao

2023报考药学专业，你给的建议是→

转自：药学士软科整理：Jasmine今年的高考已经结束，在高考志愿填报阶段，肯定会有一些考生和家长青睐医药类高校药学专业，那么，我国都有哪些实力较强的医药类高校药学专业呢？目前共有89所院校的药学专业入选国家一流药学本科专业建设点。国家一流药学本科专业建设点的梯次分布，给各分段想学药学专业的学生提供了良好的选择。如有家长问我们制药人？你如何推荐或建议呢？01药学类/中药学排名2023年6月15日，软科发布的「2023软科中国大学专业排名」显示，药学类A+专业的有北京大学、复旦大学、中国药科大学、四川大学、浙江大学等；中药学专业有北京中医药大学、上海中医药大学等。现将药学类、中药学类专业排名列出，以供各位参考。药学类排名中药学类排名2023年6月15日，软科发布了「2023软科中国大学专业排名」，此次排名共包括787个专业，涉及93个专业类和12个专业门类。这次大学专业排名是通过学校——学科——专业三个层次的评价汇总形成对专业的综合评价。排名指标体系设置学校条件、学科支撑、专业生源、专业就业、专业条件5个指标类别，共19项测量指标。 0289所高校药学专业介绍据药学士统计，目前共有89所院校的药学专业入选国家一流药学本科专业建设点。其中，既有北京大学、清华大学、复旦大学等世界一流大学，也有中国药科大学、沈阳药科大学、北京中医药大学、上海中医药大学等行业顶尖大学，还有湖南医药学院、潍坊医学院、新乡医学院、长治医学院等地方医药特色院校。国家一流药学本科专业建设点的梯次分布，给各分段想学药学专业的学生提供了良好的选择。鉴于上述院校分布在不同省份，非本省考生对部分院校的实力、概况较为陌生，药学士汇总了上述院校简介（详见下方链接，点击阅读原文可达相关院校官网），供报考者参考。中国未来，因你而耀！愿每位想报考药学专业的考生均能录取到心仪的药学类院校！中国药科大学南昌大学兰州大学浙江大学上海交通大学清华大学西南大学中南大学石河子大学山东大学中南民族大学天津大学复旦大学郑州大学武汉大学四川大学中国海洋大学西安交通大学北京大学中山大学南开大学华东理工大学北京中医药大学河北大学华中科技大学华侨大学厦门大学暨南大学吉林大学海南大学广东药科大学桂林医学院重庆医科大学沈阳药科大学广州医科大学安徽医科大学海南医学院南京医科大学安徽中医药大学温州医科大学福建医科大学北华大学江西中医药大学广西医科大学哈尔滨医科大学昆明医科大学南京中医药大学成都中医药大学延边大学宁夏医科大学杭州师范大学贵州医科大学河北医科大学大理大学新疆医科大学山西医科大学河北北方学院南方医科大学苏州大学河南大学河南中医药大学天津医科大学上海中医药大学广州中医药大学新乡医学院江苏大学湖北科技学院徐州医科大学潍坊医学院杭州医学院浙江中医药大学湖北医药学院南华大学烟台大学湖南中医药大学青岛大学浙江工业大学西南医科大学三峡大学华北理工大学成都大学黑龙江中医药大学长治医学院遵义医科大学湖南医药学院内蒙古医科大学云南中医药大学首都医科大学齐齐哈尔医学院天津中医药大学（未入选）

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