Dronedarone Hydrochloride

International Journal of Antimicrobial Agents Volume 67, Issue 11 国际抗微生物制剂杂志 67卷 11期 https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/11 International Society of Antimicrobial Chemotherapy (ISAC) News and Information Page（国际抗感染化学治疗学会（ISAC）新闻与信息专栏） 1.   International Society of Antimicrobial Chemotherapy (ISAC) News and Information Page 国际抗感染化学治疗学会（ISAC）新闻与信息专栏 Article 108015 Reviews（综述） 2.  Clinical outcomes and nephrotoxicity of polymyxin B versus colistin in real-world practice: A systematic review and meta‑analysis of observational studies 真实临床环境下多黏菌素B与黏菌素的临床疗效及肾毒性对比：观察性研究的系统综述与荟萃分析 Madhusudan Prasad Singh, Dinesh Yadav, Alok Singh Article 107902 3.  Molecular and epidemiological characteristics of cefiderocol‑resistant Klebsiella pneumoniae: Insights from genomic analysis 耐头孢地洛肺炎克雷伯菌的分子与流行病学特征：基于基因组分析的研究 Xun Jia, Shanshan Long, Yi Li, Jing Yang, ... Jie Zhang Article 107916 4.  Evaluating rapid diagnostics for severe infections and sepsis: A systematic review and meta‑analysis on behalf of the Hellenic Microbiological Society and the Hellenic Society of Chemotherapy 重症感染与脓毒症快速诊断技术评估：希腊微生物学会、希腊化学治疗学会牵头开展的系统综述及荟萃分析 Evdoxia Kyriazopoulou, Konstantinos Patras, Simeon Metallidis, Konstantina Gartzonika, ... Athanasios Tsakris Article 107937 Full Length Articles（长篇论著） 5.  HPV16E7‑specific affitoxin induces GSDME‑mediated pyroptosis via a caspase‑3‑independent pathway HPV16E7亲和毒素经由非半胱天冬酶‑3通路诱导GSDME介导的细胞焦亡 Yanheng Li, Xisha Jing, Jinhao Liu, Sicong Feng, ... Wenshu Li Article 107911 6.  Real‑world evaluation of HIV‑1 reservoir and resistance in virologically suppressed people after 52 weeks of treatment with long‑acting cabotegravir + rilpivirine 长效卡博特韦‑利匹韦林治疗52周后病毒抑制感染者体内HIV‑1储存库与耐药情况的真实世界研究 Greta Marchegiani, Francesco Paolo Antonucci, Ada Bertoli, Maria Concetta Bellocchi, ... Maria Mercedes Santoro Article 107907 7.  Mechanisms underlying altered ceftazidime‑avibactam resistance in Klebsiella pneumoniae driven by KPC‑234 mutation and IncX3‑NDM‑1 plasmid transfer KPC‑234基因突变与IncX3‑NDM‑1质粒转移介导肺炎克雷伯菌发生头孢他啶‑阿维巴坦耐药变异的作用机制 Yunqi Pan, Chengkang Tang, Yanan Lai, Renru Han, ... Fupin Hu Article 107900 8.  Cefiderocol non-susceptibility among carbapenem-resistant Enterobacterales: Data from the 2024 Antimicrobial Testing Leadership and Surveillance (ATLAS) programme 耐碳青霉烯类肠杆菌目细菌对头孢地尔的非敏感情况：2024 年抗菌药物试验主导监测（ATLAS）项目数据 Po-Wei Chiu, Jiun-Ling Wang, Shun-Chung Hsueh, Nan-Yao Lee, ... Po-Ren Hsueh Article 107932 9.  Integrated multi-omics profiling reveals the role of the cfa gene in mediating penicillin antibiotics resistance and stress adaptability in Shigella sonnei 多组学联合分析揭示 cfa 基因在介导宋内志贺菌青霉素耐药与环境胁迫适应能力中的作用 Juan Geng, Yanlei Gao, Wenyao Su, Jinzhao Long, ... Guangcai Duan Article 107931 10.  The T6SS effector Hcp of hypervirulent Klebsiella pneumoniae exacerbates liver abscess by inducing macrophage-HMGB1/RAGE-dependent endothelial pyroptosis 高毒力肺炎克雷伯菌 T6SS 效应蛋白 Hcp 通过巨噬细胞‑HMGB1/RAGE通路介导的内皮细胞焦亡加重肝脓肿 Bo Ni, Zhaoyu Liu, Zhihui Chang, Hairui Wang Article 107933 11.  Dual-threat ascent of carbapenem-resistant Klebsiella aerogenes: Plasmid-borne resistance-virulence convergence and global kinship 耐碳青霉烯产气克雷伯菌的双重威胁态势：质粒介导的耐药‑毒力耦合及全球亲缘关系分析 Yi Liu, Ruishan Liu, Hao Xu, Beiwen Zheng Article 107928 12.  Voriconazole exacerbates subtherapeutic linezolid exposure in critically ill patients with Staphylococcus aureus infection: Drug-drug interaction evaluation and dose optimisation based on population modelling and ensemble learning 伏立康唑加重金黄色葡萄球菌感染危重症患者的利奈唑胺亚治疗暴露：基于群体模型与集成学习的药物‑药物相互作用评估及剂量优化 Haofan Zhang, Feng Wang, Ru Liao, Weishang Deng, ... Haiyan Dong Article 107942 13.  Vonoprazan-based dual and quadruple therapy with varying duration for Helicobacter pylori eradication: A multicenter, randomised controlled trial 基于伏诺拉生不同疗程的双联与四联方案根除幽门螺杆菌：一项多中心随机对照试验 Kunping Ju, Hanyue Zhao, Leina Guo, Zhenzhen Zhai, ... Yanqing Li Article 107948 14.  Optimising the meropenem dosing regimen in neonates: A dual-centre cohort study 优化新生儿美罗培南给药方案：一项双中心队列研究 Tao Zhang, Hua Cheng, Xinyan Han, Qian Du, ... Yalin Dong Article 107944 15.  Precision redosing of oritavancin: A population pharmacokinetic framework to optimize long-term therapy for complex gram-positive infections 奥利万星精准复剂量给药：用于优化复杂革兰阳性菌感染长期治疗的群体药代动力学模型框架 Simone Giuliano, Antonio D'Avolio, Jacopo Angelini, Amedeo de Nicolò, ... Manjunath P. Pai Article 107943 16.  Antimicrobial prophylaxis regimens in joint replacement surgery: Susceptibility and PK/PD target attainment 关节置换手术的抗菌药物预防方案：药敏结果与药代动力学/药效学目标达成情况 Alba Rivera, Sonia Luque, Isabel Mur, Lluís Puig-Verdié, ... Natividad Benito Article 107947 17.  An exploratory pharmacokinetic-pharmacodynamic analysis of ceftazidime-avibactam and various blood biomarkers in patients with hospital-acquired pneumonia or ventilator-associated pneumonia caused by Klebsiella pneumoniae 肺炎克雷伯菌所致医院获得性或呼吸机相关性肺炎患者中头孢他啶‑阿维巴坦与多种血液生物标志物的探索性药代‑药效学分析 Amaury O’Jeanson, Elisabet I. Nielsen, Zoe Athanassa, Aghavni Ginosyan, ... Lena E. Friberg Article 107946 18.  Association between tazobactam–piperacillin exposure and the subsequent emergence in gram-negative rods: Findings from a single-institution cohort study 他唑巴坦‑哌拉西林暴露与革兰氏阴性杆菌后续耐药菌株产生的关联：单中心队列研究结果 Ezaki Masayoshi, Kato Noriko, Nagaoka Kentaro, Murai Yushi, ... Yamamoto Yoshihiro Article 107953 19.  Risk stratification of voriconazole-induced hepatotoxicity through therapeutic drug monitoring combined with the albumin–bilirubin score: A multicenter retrospective cohort study in Japan 基于治疗药物监测联合白蛋白‑胆红素评分的伏立康唑致肝毒性风险分层：一项日本多中心回顾性队列研究 Yuki Asai, Yuki Nakano, Hayato Akamatsu, Hiroki Katsu, ... Takuya Iwamoto Article 107949 20.  Early prediction of carbapenem resistance phenotype in ICU-acquired Acinetobacter baumannii infection before susceptibility reporting: A temporally validated study 药敏报告出具前对 ICU 获得性鲍曼不动杆菌感染碳青霉烯耐药表型的早期预测：一项时间验证研究 Meng Zhou, Yaling Zhou, Chengxiang Xiang, Yiting Liu, ... Zhongle Cheng Article 107957 21.  Celastrol inhibits Streptococcus suis infection through disrupting arginine metabolism pathway 雷公藤红素通过破坏精氨酸代谢通路抑制猪链球菌感染 Hongdou Liu, Shichao Xu, Rui Lei, Xiaoying Yu, ... Lianci Peng Article 107966 22.  Development of the susceptibility–spectrum discrepancy index (S2DI): A novel metric for antimicrobial stewardship in hospitalised patients 药敏-谱差异指数（S2DI）的构建：一项用于住院患者抗菌药物管理的新型评价指标 Shinya Tsuzuki, Ryuji Koizumi, Yusuke Asai, Yuuki Hashimoto, ... Norio Ohmagari Article 107954 23.  Impact of an antimicrobial stewardship intervention on clinical and economic outcomes in outpatient parenteral antimicrobial therapy (OPAT) for urinary tract infections: A quasi-experimental study 抗菌药物管理干预对门诊胃肠外抗菌治疗（OPAT）尿路感染患者临床与经济学结局的影响：一项准实验研究 Silvia Gómez-Zorrilla, Rosa Ana Sabaté, Inmaculada López Montesinos, Ariadna Brasè, ... Jesús Rodríguez-Baño Article 107955 24.  Intrapulmonary pharmacokinetics and safety of eravacycline in critically ill patients with HAP/VAP caused by carbapenem-resistant Acinetobacter baumannii and Enterobacterales: A prospective study 艾拉环素在耐碳青霉烯鲍曼不动杆菌与肠杆菌目所致医院获得性肺炎/呼吸机相关性肺炎重症患者中的肺内药代动力学及安全性：一项前瞻性研究 Jingjing He, Nanyang Li, Xin Li, Yuancheng Chen, ... Jing Zhang Article 107960 25.  Drivers of antimicrobial resistance gene clustering in plasmids: Distribution, host clinical relevance, and plasmid mobility 质粒中耐药基因簇的形成驱动因素：分布特征、宿主临床意义与质粒可移动性 Célia P.F. Domingues, João S. Rebelo, Francisco Dionisio, Teresa Nogueira Article 107964 26.  FIRL potentiates antibiotic activity against multidrug-resistant Gram-negative bacteria: Selective BamA–BamD interface perturbation induces functional outer membrane vulnerability FIRL增强抗生素对多重耐药革兰阴性菌的活性：选择性干扰BamA–BamD界面诱发外膜功能缺陷 Wenwen Li, Bingjie Ji, Weixuan Wen, Jiale Tuo, ... Yongshan Zhao Article 107971 27.  Genomic epidemiology and ceftazidime-avibactam resistance mechanism of KPC-3-producing Pseudomonas aeruginosa: A decade retrospective study in China 产KPC-3铜绿假单胞菌的基因组流行病学及头孢他啶-阿维巴坦耐药机制：中国一项十年回顾性研究 Longjie Zhou, Zhiqiang Zhu, Xiaofei Zhao, Lu Ye, ... Xi Li Article 107972 28.  Electronic-nomogram-guided micafungin dosing regimen in critically ill patients: A population pharmacokinetic study 基于电子列线图指导重症患者米卡芬净给药方案：一项群体药代动力学研究 Jean-Joseph Bendjilali-Sabiani, Ahlem Gammoudi, Matthieu Conseil, Samir Jaber, Yoann Cazaubon Article 107970 29.  Carbapenemase-producing Acinetobacter baumannii from Spanish hospitals, 2016–2020: Interregional spread of ST2PAS isolates co-harbouring blaOXA-23, blaOXA-66 and armA genes 2016–2020年西班牙医院产碳青霉烯酶鲍曼不动杆菌：同时携带blaOXA-23、blaOXA-66与armA基因的ST2PAS菌株跨区域传播 Jared Sotelo, Belén Aracil, Jorge Arca-Suárez, Marta Gil-Martinez, ... María Pérez-Vázquez Article 107967 30.  Emergence of cefiderocol resistance in carbapenem-resistant Escherichia coli ST167 prior to clinical use: A multifactored resistance landscape 临床应用前即出现头孢地尔耐药的ST167型耐碳青霉烯大肠埃希菌：多因素耐药谱特征 Ruiqi Wang, Shuo Yang, Longyang Jin, Bowen Li, ... Qi Wang Article 107958 31.  Population pharmacokinetics of daptomycin in patients with haematological malignancies and vancomycin-resistant Enterococcus bloodstream infections 达托霉素在合并耐万古霉素肠球菌血流感染的血液系统恶性肿瘤患者中的群体药代动力学 Kelly A. Cairns, Zi Xing Mun, Andrew A. Udy, Trisha N. Peel, ... Anton Y. Peleg Article 107974 32.  CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicentre Pharmacokinetics and Pharmacodynamics Population Study 利奈唑胺在伴/不伴中枢神经系统医院获得性感染的重型脑损伤患者脑脊液中的药代动力学-药效学：PK-Pop-LCR多中心群体PK/PD研究 Claire Dahyot-Fizelier, Alexia Chauzy, Kévin Chalard, Fanny Bernard, ... Yoann LAUNEY Article 107969 33.  Host inflammation drives low-exposure nephrotoxicity in critically ill patients receiving polymyxin B: A prospective study 宿主炎症介导重症患者使用多黏菌素B时低暴露剂量下的肾毒性：一项前瞻性研究 Xuemei Luo, Dayu Chen, Huaijun Zhu, Pei Liang, ... Weihong Ge Article 107980 Short Communications（短篇通讯） 34.  Rapid achievement of protective cabotegravir concentrations in a real‑world HIV PrEP cohort HIV暴露前预防真实队列中机体可快速抵达具备保护效力的卡博特韦血药浓度 Davide Moschese, Chiara Fusetti, Samuel Lazzarin, Francesco Petri, ... Maria Vittoria Cossu Article 107926 35.  Kidney injury, dialysis, and mortality with vancomycin plus piperacillin–tazobactam or cefepime 万古霉素联用哌拉西林‑他唑巴坦或头孢吡肟所致肾损伤、透析需求与死亡风险对比 Joseph Magagnoli, Tammy H. Cummings, Christopher M. Bland, S. Scott Sutton Article 107897 36.  Outcomes for persons with triple‑class resistant HIV and a history of virologic failure 存在病毒学失败史的三类药物耐药HIV感染者的临床预后 Suzanne M. Ingle, Fabrice Bonnet, Linda Wittkop, Alexandra Calmy, ... Mojgan Hessamfar Article 107925 37.  Rezafungin in the management of patients with Candida osteoarticular infections: Results from the REZ-GEIO project 瑞扎芬净用于念珠菌骨关节感染患者的临床救治：REZ‑GEIO 项目研究结果 Sofía De La Villa, Jesús Guinea, Joan Gómez-Junyent, Mar Sánchez-Somolinos, ... Patricia Muñoz Article 107927 38.  An exploration of the effectiveness and safety of 7‑d triple therapy with amoxicillin and tetracycline for Helicobacter pylori eradication: A propensity score matching analysis 阿莫西林‑四环素七日三联疗法根除幽门螺杆菌的疗效与安全性探究：一项倾向得分匹配分析 Kunping Ju, Baobao Wang, Qingzhou Kong, Yueyue Li, ... Yanqing Li Article 107930 39.  Comparator choice in Helicobacter pylori eradication: Tegoprazan-amoxicillin dual therapy vs. an optimised bismuth-containing quadruple therapy in a randomised trial and meta-analysis 幽门螺杆菌根除方案的对照选择：基于随机试验与荟萃分析对比替戈拉生‑阿莫西林二联疗法和优化铋剂四联疗法 Miao Duan, Qingzhou Kong, Hui Wang, Xiaoqi Wu, ... Xiuli Zuo Article 107929 40.  ISCR28 is associated with initial armA capture and provides promoter activity for its expression ISCR28 与 armA 的初始捕获相关并为其表达提供启动子活性 Min Yuan, Lu Nie, Bingqian Du, Hongquan Chen, ... Zhenjun Li Article 107936 41.  Pharmacogenomic variability in adolescents and youth with virologic rebound while receiving injectable cabotegravir/rilpivirine: A multi-case series 接受注射用卡博特韦/利匹韦林治疗出现病毒学反弹青少年及青年的药物基因组学变异：多病例系列 Timothy J. Howze, Susan D. Carr, Nehali D. Patel Article 107945 42.  Staphylococcus epidermidis implant-associated bone and joint infections: high rates of multiresistance associated with treatment failure 表皮葡萄球菌植入物相关骨关节感染：多重耐药高发与治疗失败相关 Michaela Schumacher, Flurin Grob, Jan A. Roth, Adrian Egli, ... Richard Kuehl Article 107950 43.  Therapeutic drug monitoring of aztreonam-avibactam in critically ill patients with CRKP infections and variable renal function: A case series 肾功能波动的重症 CRKP（碳青霉烯耐药肺炎克雷伯菌）感染患者氨曲南‑阿维巴坦的治疗药物监测：一项病例系列研究 Guanghui Chen, Qiang Qu, Yiwen Xiao, Feng Wang, ... Jian Qu Article 107962 44.  Impact of timing of aggressive joint PK/PD target attainment of continuous infusion piperacillin-tazobactam on early clinical response of febrile neutropenia to antimicrobial treatment: Insights from a prospective, monocentric, observational study in paediatric hematopoietic stem cell recipients 持续输注哌拉西林‑他唑巴坦强化联合药代动力学/药效学靶标达成时机对发热性中性粒细胞减少症抗菌治疗早期临床应答的影响：一项针对儿童造血干细胞移植受者的单中心前瞻性观察性研究 Milo Gatti, Davide Leardini, Caterina Campoli, Francesco Venturelli, ... Federico Pea Article 107956 45.  Triple carbapenemase-producing Klebsiella pneumoniae ST6668 resistant to novel β-lactam/β-lactamase inhibitor combinations and cefiderocol, Northern Italy, 2025 2025年意大利北部同时产三种碳青霉烯酶的ST6668肺炎克雷伯菌：对新型β内酰胺/β内酰胺酶抑制剂复方及头孢地尔耐药 Vittoria Mattioni Marchetti, Nicole Giorgi, Francesca Piscopiello, Ilaria Petrizzi, ... Roberta Migliavacca Article 107977 46.  Development of antibiotic-associated diarrhoea in sepsis patients is associated with dysbiosis at baseline: Data from the PROGRESS Controlled Trial 脓毒症患者发生抗生素相关性腹泻与基线菌群失调相关：PROGRESS对照研究数据 Evdoxia Kyriazopoulou, Emmanouil Stylianakis, Georgia Damoraki, Andronikos Spyrou, ... Evangelos J. Giamarellos-Bourboulis Article 107979 Letters to the Editor（致编辑的信） 47.  Comment on strain‑dependent variability in pharmacodynamic interactions for phage‑antibiotic combinations in Pseudomonas aeruginosa 针对铜绿假单胞菌噬菌体‑抗生素联合用药药效相互作用存在菌株差异性的评述 Zhichao Zhao, Ting Shen Article 107935 48.  Comment on “Cefiderocol susceptibility rates in carbapenem-resistant Gram-negative bacteria in a comparative, multicentre surveillance study in China” 《中国多中心对比监测研究中耐碳青霉烯类革兰阴性菌的头孢地洛科尔药物敏感率》一文述评 Sachin Kumar, Nirupma Gupta, Sujeet Kumar Singh, Hariharan Srinivasan, ... Brajgopal Kushwaha Article 107934 49.  In reply to comment on “Risk factors and serum concentration thresholds associated with tigecycline-induced hepatotoxicity in critically ill patients” 针对《危重症患者替加环素致肝毒性相关危险因素及血清浓度阈值》一文评论的回复 Mengxue Li, Jie He, Gaoqiu Dong, Hua Shao, Linlin Hu Article 107924 50.  A novel blaTMB allele encoding a functional carbapenemase associated with a gamma-mobile-trio island 与γ‑mobile‑trio基因岛相关、编码功能性碳青霉烯酶的新型*bla*TMB等位基因 Sergio Mascarenhas Morgado, Erica Lourenço Fonseca, Ana Carolina Paulo Vicente Article 107941 51.  Comment on “Burden and global distribution of antimicrobial resistance in non-bloodstream infections among adults with cirrhosis: A systematic review and proportional meta-analysis” 对《成人肝硬化非血流感染的抗菌药物耐药负担及全球分布：系统综述与比例Meta分析》一文的评述 Jiandi Li Article 107951 52.  Comment on ‘Cefiderocol susceptibility rates in carbapenem-resistant Gram-negative bacteria in a comparative, multicenter surveillance study in China’ 评述《中国一项多中心比较监测研究中耐碳青霉烯革兰阴性菌的头孢地尔药敏率》 Jiandi Li Article 107978 53.  Doxycycline-containing combination therapy for multidrug-resistant Gram-negative ventilator-associated pneumonia: A prospective observational study 含多西环素联合方案治疗多重耐药革兰阴性菌呼吸机相关性肺炎：一项前瞻性观察研究 Zoe Athanassa, Sofia Manioudaki, Iosif Bader, Irina Petsa, ... Athanasios Tsakris Article 107973 54.  Identification of a Novel SHV Beta-Lactamase With a Tetrapeptide Duplication in the Omega Loop and a Resistance Profile Resembling SHV-16 发现一种ω环存在四肽重复、耐药表型类似SHV-16的新型SHVβ内酰胺酶 Annelie Müller, Martin A. Fischer, Guido Werner, Michael Weig, Yvonne Pfeifer Article 107963 55.  Comment on ‘Cefiderocol susceptibility rates in carbapenem-resistant Gram-negative bacteria in a comparative, multicentre surveillance study in China’ 评述《中国一项多中心比较监测研究中耐碳青霉烯革兰阴性菌的头孢地尔药敏率》 Bageshree N. Pande, Esha Singhal, Palavardhan Peddapalegani, Arun Kumar, Fayaz Ahamed Article 107975 56.  In reply to the letter to editor regarding: “Strain-dependent variability in pharmacodynamic interactions for phage-antibiotic combinations in Pseudomonas aeruginosa” 回复致编辑信：《铜绿假单胞菌中噬菌体-抗生素联合方案药效学相互作用存在菌株依赖性差异》 Laura R. Baars, Meng Gu, Tingjie Guo, J.G. Coen van Hasselt Article 107968 International Journal of Antimicrobial Agents Volume 67, Issue 12 国际抗微生物制剂杂志 67卷 12期 https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/12 Klebsiella pneumoniae（肺炎克雷伯菌） 1.  Remodelling the host immune microenvironment in carbapenem-resistant Klebsiella pneumoniae: An evidence-graded framework for host-directed intervention 耐碳青霉烯肺炎克雷伯菌感染中宿主免疫微环境重塑：宿主导向干预的证据分级框架 Xiaolin Liang, Junwei Wang, Chao Liu, Qingyuan Gao, ... Yan He Article 108000 Reviews（综述） 2.  Pharmacokinetic and pharmacokinetic/pharmacodynamic (PK/PD) considerations of ceftaroline and ceftobiprole for the treatment of Staphylococcus aureus infections: A systematic review 头孢洛林与头孢比罗治疗金黄色葡萄球菌感染的药代动力学及药代/药效学（PK/PD）考量：系统评价 Camilla Genovese, Marta Colaneri, Enrico Sguazzini, Donatella Maddalena, ... Marta Ulldemolins Article 107959 3.  Antibiotic resistance in Helicobacter pylori: pathogenic mechanisms and eradication barriers 幽门螺杆菌的抗生素耐药性：致病机制与根除障碍 Meenakshi Kandpal, Siddharth Singh, Harshita Shrivastava, Himanshi Jindal, ... Hem Chandra Jha Article 107981 4.  Clinical pharmacology and therapeutic considerations of isavuconazole in special populations: A narrative review 艾沙康唑在特殊人群中的临床药理学特征与治疗考量：叙述性综述 Shichao Zhu, Rongsong Xia, Jing Yang, Fei Tang, ... Xuewen Qiu Article 108005 5.  Nipah virus: An exceptionally virulent emerging zoonotic pathogen 尼帕病毒：一种高毒力新发人兽共患病病原体 Hao Sun, Xin Yuan, Jinyan Li, Xitang Li, ... Guangcai Duan Article 107990 6.  Examining the global antimicrobial resistance surveillance landscape in food-producing animals 食用动物全球抗菌药物耐药性监测体系现状探析 Vika Li, Shaina Craig, Shabbir Simjee Article 108008 Full Length Articles（全文论著） 7.  Proteomics reveals the mechanism by which sodium oleate decreases Escherichia coli susceptibility to gentamicin 蛋白质组学揭示油酸钠降低大肠埃希菌对庆大霉素敏感性的机制 Lvyuan Fan, Jingyun Wu, Ziyi Zhang, Liting Cai, ... Guozhu Ye Article 107989 8.  Real-world use of liposomal amphotericin B: A large retrospective, observational, multicentre study 脂质体两性霉素 B 在现实中的应用：一项大型回顾性观察性多中心研究 Claudia Bartalucci, Daniele Roberto Giacobbe, Marco Muccio, Silvia Sisto, ... Giulia Viero Article 107952 9.  Global burden of bacterial antimicrobial resistance among children under 5 years 1990−2021: A systematic analysis with forecasts to 2050 1990—2021年全球5岁以下儿童细菌耐药性疾病负担：系统分析及至2050年预测 Shanshan Wang, Fei Xie, Shaowei Sang Article 107995 10.   Evaluation of vancomycin bolus/standard and continuous infusion on nephrotoxicity in a rat model 大鼠模型中万古霉素推注/常规给药与持续输注方案的肾毒性评价 Sylwia Marianski, Gwendolyn M. Pais, Colin Jeantet, Renz Paulo Melicor, ... Marc H. Scheetz Article 107988 11.   Prevalence of third-generation cephalosporin-resistant Salmonella in animals in China: The key role of ESBL, AmpC, and other β-lactamase strains in the genome 我国动物源第三代头孢菌素耐药沙门菌流行情况：ESBL、AmpC 及其他 β- 内酰胺酶菌株在基因组中的关键作用 Fangqin Liu, Lu Zhang, Qi Zhao, Min Cheng, ... Chunping Zhang Article 107992 12.   Real-world safety signals of fluoroquinolone-associated peripheral neuropathy: Analysis of US and Canadian databases combined with mechanistic exploration 氟喹诺酮类药物相关周围神经病变在现实中的安全信号：美、加数据库联合分析及机制探讨 Bingjian Guo, Ziwei Zou, Junfei Lu, Shimei Tan, Lingyan Mai Article 107993 13.   Appropriate therapy and survival in carbapenem-resistant Enterobacterales bacteraemia: A multicentre cohort study on epidemiology and risk factors 碳青霉烯耐药肠杆菌科细菌菌血症的恰当治疗与生存率：一项关于流行病学及危险因素的多中心队列研究 Yae Jee Baek, Se Yoon Park, Jung Ho Kim, Hye Seong, ... Yoon Soo Park Article 108001 14.   Ecological antagonism constrains receptor-diverse phage cocktail efficacy against multidrug-resistant Enterobacter hormaechei 生态拮抗作用限制受体多样性噬菌体鸡尾酒制剂对多重耐药霍氏肠杆菌的疗效 Bai-Ling Zhang, Ming-Yu Jiang, Xiu-Zhen Chen, Xiao-Qi Yang, ... Wei Chen Article 108004 15.   Genomic epidemiology and resistance determinants of Pseudomonas aeruginosa in bronchiectasis across China: A multicentre study 全国支气管扩张患者铜绿假单胞菌的基因组流行病学及耐药决定因子研究：一项多中心研究 Linlin Xu, Qing Chen, Aikuang Ma, Kang Xu, ... Xiaoli Wang Article 108010 16.   Pharmacovigilance signals and regional burden of antibiotic-associated Clostridioides difficile infection: A pharmacovigilance study and Global Burden of Disease Study 2023 药物警戒信号与抗生素相关艰难梭菌感染的区域疾病负担：一项药物警戒研究及 2023 年全球疾病负担研究 Dain Y. Kim, Hyunjeong Kim, Hyunyi Yoo, Hyoin Shin, ... Dong Keon Yon Article 108013 17.   Aztreonam-avibactam activity against Enterobacterales from Asia Pacific and Latin American medical centres: Summary of 5 years of surveillance prior to clinical use (2020–2024) 氨曲南 - 阿维巴坦对亚太及拉美地区医疗机构肠杆菌目细菌的抗菌活性：临床应用前 5 年监测汇总（2020–2024） Helio S. Sader, Rodrigo E. Mendes, John H. Kimbrough, Krisztina M. Papp-Wallace, Mariana Castanheira Article 108003 18.   Vancomycin population pharmacokinetics and optimized dosing in critically ill infants and children 危重症婴幼儿万古霉素群体药代动力学与优化给药方案 Tavey Dorofaeff, Xin Liu, Emmanuel Novy, Mark G. Coulthard, ... Jason A. Roberts Article 108006 19.   Pulmonary penetration of intravenous rifabutin in healthy participants: A multiple-dose pharmacokinetic study 健康受试者静脉输注利福布汀的肺组织穿透性：一项多剂量药代动力学研究 Valentin al Jalali, Anselm Jorda, Lena Pracher, Amelie Leutzendorff, ... Markus Zeitlinger Article 108014 20.   A clinical prediction model to support risk-adapted fibrinogen monitoring during tigecycline therapy: Multicentre development and validation 替加环素治疗期间用于风险分层纤维蛋白原监测的临床预测模型：多中心构建与验证 Jinlin Guo, Xinfeng Cai, Yayu Huo, Hongping Wen, ... Ruigang Hou Article 108012 Short Communications（短篇通讯） 21.   Long-term treatment durability and safety after switching to bictegravir/emtricitabine/tenofovir alafenamide in real-world practice: a 144-week update from the BICTEL cohort 真实世界中换用比克替拉韦/恩曲他滨/丙酚替诺福韦后的长期疗效持久性与安全性：BICTEL队列144周更新数据 Luca Bortolani, Riccardo Donà, Antonietta Impellizzeri, Vlad Racolta, ... Gabriella d'Ettorre Article 107991 22.   Daptomycin or linezolid versus vancomycin for the treatment of vancomycin-susceptible Enterococcus faecium bloodstream infections 达托霉素或利奈唑胺对比万古霉素治疗万古霉素敏感型屎肠球菌血流感染 Samantha Poloni, Timothée Klopfenstein, Adrien Biguenet, Mathieu Blot, ... Anne-Sophie Brunel Article 107994 23.   Silent carriage of tigecycline- and carbapenem-resistant Klebsiella quasipneumoniae co-harbouring tet(X4) and blaNDM-1 in healthy individuals in China 国健康人群中携带tet(X4)与blaNDM-1基因的耐替加环素及碳青霉烯类准肺炎克雷伯菌的静默携带现象 Jing Wang, Zelin Yan, Heng Shen, Ling Xin, ... Rong Zhang Article 108009 24.   Caspofungin pharmacokinetics in a child undergoing continuous veno-venous haemodiafiltration: A case report 接受连续性静脉 - 静脉血液透析滤过治疗患儿的卡泊芬净药代动力学：1 例病例报告 Noémie de Cacqueray, Agathe Béranger, Leo Froelicher Bournaud, Mathilde Grapin, ... Mehdi Oualha Article 108002 Letters to the Editor（致编辑信） 25.   Comment on "stepwise within-host evolution of a blaCTX-M-27-positive Klebsiella pneumoniae clone under changing antimicrobial pressures leading to enhancement of β-lactam resistance" 评述《抗菌药物压力变化下产blaCTX-M-27肺炎克雷伯菌克隆株在宿主体内逐步进化并增强β内酰胺耐药性》 Evy Diah Woelansari, Sari Luthfiyah, Juliana Christyaningsih, Tacik Idayanti, Anita Dwi Anggraini Article 107987 26.   blaNDM-4-carrying Klebsiella pneumoniae: an uncommon but epidemiologically informative signal in public genomes 携带blaNDM-4基因的肺炎克雷伯菌：公开基因组中一种少见但具流行病学提示价值的信号 Yan Feng, Yu Feng, Xiaoting Hua, Chao Zhuo, Zhiyong Zong Article 107982 27.   Comment on “Aztreonam–avibactam pharmacokinetics during extracorporeal membrane oxygenation support: First insights from a case report” 对《体外膜肺氧合支持期间氨曲南 - 阿维巴坦的药代动力学：一则病例报告的初步探索》的评论 Guanghui Chen, Haibo Lei, Liang Long, Xiang Liu Article 107961 28.   Comment on “The antiarrhythmic drugs dronedarone and amiodarone exhibit potent in vitro and in vivo activity against clostridioides difficile” 对《抗心律失常药物决奈达隆与胺碘酮在体内外均具有强大的艰难梭菌抑制活性》的评论 Zareena Begum Shaik, Thirupathi Gorre, Harikiran Lingabathula Article 107976 29.   In reply to the letter to editor regarding ‘discrepancy between WGS-based genotypic and phenotypic drug susceptibility testing of first and second-line drugs for Mycobacterium tuberculosis: Limited impact of unknown resistance mechanisms’ 回复致编辑信：《结核分枝杆菌一线与二线药物基于全基因组测序的基因型药敏试验与表型药敏试验结果不一致：未知耐药机制的影响有限》 Peng Xu, Qian Gao Article 107999 30.   In Reply to the Letter to Editor Regarding Tissue Pharmacokinetics of Antifungal Drugs: A Review 回复致编辑的信：《抗真菌药物的组织药代动力学：综述》 Felix Bergmann, Marlene Prager, Markus Zeitlinger Article 107996 31.   In reply to letter to editor regarding ``a multicenter, randomised, double-blind, imipenem/cilastatin-controlled clinical study of cefiderocol for the treatment of complicated urinary tract infections caused by Gram-negative pathogens in Chinese adults'' 回复致编辑的信：《头孢地尔治疗中国成人革兰阴性菌所致复杂性尿路感染的多中心、随机、双盲、以亚胺培南 / 西司他丁为对照的临床研究》 Jinyi Yuan, Deyong Fan, Henglan Wu, Bei Jia, ... Yingyuan Zhang Article 107983 32.   In reply to the Letter to the Editor regarding “Disrupting bacterial metabolism by targeting LDH reverses aminoglycoside resistance in Streptococcus suis” 针对《靶向乳酸脱氢酶干扰细菌代谢可逆转猪链球菌对氨基糖苷类药物的耐药性》一文致编者信的回复 Yang Wang, Shuji Gao, Baobao Liu, Yuxin Wang Article 108007 33.   Comment on “Discrepancy between WGS-based genotypic and phenotypic drug susceptibility testing of first- and second-line drugs for Mycobacterium tuberculosis: Limited impact of unknown resistance mechanisms” 对《结核分枝杆菌一线及二线药物基于全基因组测序的基因型药敏试验与表型药敏试验结果不一致性：未知耐药机制的影响有限》一文的述评 Manish R. Bhise, Akshay Akotkar, Shweta Bhandari, Kuldip V. Gite Article 107997