预约演示
更新于：2026-10-28
Cefiderocol Sulfate Tosylate
硫酸甲苯磺酸头孢德罗
更新于：2026-10-28
概要
基本信息
药物类型 小分子化药 |
别名 Cefiderocol、Cefiderocol sulfate tosilate、Cefiderocol sulfate tosylate (USAN) + [19] |
靶点 |
作用方式 抑制剂 |
作用机制 PBPs抑制剂(细菌青霉素结合蛋白家族抑制剂) |
在研适应症 |
最高研发阶段批准上市 |
最高研发阶段(中国)批准上市 |
特殊审评快速通道 (美国)、孤儿药 (日本) |
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结构/序列
分子式C30H34ClN7O10S2 |
InChIKeyDBPPRLRVDVJOCL-FQRUVTKNSA-N |
CAS号1225208-94-5 |
关联
30
项与 硫酸甲苯磺酸头孢德罗 相关的临床试验NCT07759453
Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase-producing Enterobacterales Undergoing Liver Transplantation: a Stepped Wedge Cluster Randomization Trial
This is a multicenter stepped-wedge cluster randomized trial, conducted over a 2-year period at three hospitals. The trial is structured into four phases, each lasting six months. During phase 1 (pre-rollout), all hospitals will use standard antibiotic prophylaxis for all patients. In each of phases 2 to 4, one hospital will switch to targeted antibiotic prophylaxis, so that by phase 4 all hospitals will be using it. The order in which hospitals switch is determined by computer-generated randomization performed centrally by an independent statistician, ensuring each hospital has an equal chance of switching at any given phase and minimizing selection bias.
The goal of this clinical trial is to learn whether targeted antibiotic prophylaxis works better than standard antibiotic prophylaxis at preventing infections in liver transplant patients who carry resistant bacteria called CPE (carbapenemase-producing Enterobacterales). It will also learn about the effects of these antibiotics on gut bacteria.
The main questions it aims to answer are:
* Does targeted antibiotic prophylaxis reduce the number of CPE infections occurring in the first two weeks after liver transplant, compared to standard prophylaxis?
* How do targeted and standard antibiotic prophylaxis affect the gut microbiome after transplant?
* Is there a link between achieving optimal antibiotic blood levels and the risk of developing an infection after transplant?
Researchers will compare targeted antibiotic prophylaxis (chosen based on the specific bacteria each patient carries) to standard antibiotic prophylaxis (used routinely at each hospital) to see which approach better prevents infection.
This study does not involve the administration of any drugs or instrumental examinations beyond those already part of standard clinical care at each center. However, additional blood tests will be performed by collecting one extra blood sample (and a bile sample, if the patient has a Kehr's tube, which is a drain placed in the bile duct after surgery) during blood draws already scheduled as part of routine clinical practice, in order to measure drug levels in the blood. Stool samples will also be collected specifically for the study to investigate the gut microbiome.
The goal of this clinical trial is to learn whether targeted antibiotic prophylaxis works better than standard antibiotic prophylaxis at preventing infections in liver transplant patients who carry resistant bacteria called CPE (carbapenemase-producing Enterobacterales). It will also learn about the effects of these antibiotics on gut bacteria.
The main questions it aims to answer are:
* Does targeted antibiotic prophylaxis reduce the number of CPE infections occurring in the first two weeks after liver transplant, compared to standard prophylaxis?
* How do targeted and standard antibiotic prophylaxis affect the gut microbiome after transplant?
* Is there a link between achieving optimal antibiotic blood levels and the risk of developing an infection after transplant?
Researchers will compare targeted antibiotic prophylaxis (chosen based on the specific bacteria each patient carries) to standard antibiotic prophylaxis (used routinely at each hospital) to see which approach better prevents infection.
This study does not involve the administration of any drugs or instrumental examinations beyond those already part of standard clinical care at each center. However, additional blood tests will be performed by collecting one extra blood sample (and a bile sample, if the patient has a Kehr's tube, which is a drain placed in the bile duct after surgery) during blood draws already scheduled as part of routine clinical practice, in order to measure drug levels in the blood. Stool samples will also be collected specifically for the study to investigate the gut microbiome.
开始日期2026-10-01 |
CTIS2024-516232-10-00
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
开始日期2026-07-31 |
NCT07431307
A Two-part Phase IIb Randomized, Multicenter, Open-label Comparative Study to Firstly Evaluate the Safety and Efficacy Trial of BV100 in Combination With Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol Versus Best Available Therapy in Patients With Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia and Bloodstream Infection, Suspected or Confirmed to be Due to Carbapenem-resistant Acinetobacter Baumannii Calcoaceticus Complex (CRABC), and Secondly to Evaluate the Pharmacokinetics of BV100 in Combination With Low Dose Polymyxin B Plus Cefideroc
This Phase IIb study aims to evaluate the safety and efficacy of BV100 in combination with low dose polymyxin B plus ceftazidime/avibactam or cefiderocol in patients with suspected or confirmed CRABC infections. The study is divided into two parts (Part A and Part B), recruiting in parallel. Approximately 10 subjects will be recruited in Part B, with enrollment ending once Part A enrollment is complete (at least 30 patients randomized to all of the three groups). Eligible patients, who have given informed consent, will be enrolled, and pre-treatment microbiology samples submitted to a local laboratory.
开始日期2026-07-01 |
申办/合作机构 |
100 项与 硫酸甲苯磺酸头孢德罗 相关的临床结果
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100 项与 硫酸甲苯磺酸头孢德罗 相关的转化医学
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100 项与 硫酸甲苯磺酸头孢德罗 相关的专利（医药）
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1,038
项与 硫酸甲苯磺酸头孢德罗 相关的文献（医药）2027-05-01·Value in Health Regional Issues
Development and Real-World Application of a Consumption-Based Model for Projecting the Budget Impact of High-Cost Reserve Antibiotics in a University Hospital
Article
作者: Polito, Giacomo ; Martellone, Lorenzo ; Mastroianni, Claudio Maria ; Sacco, Federica ; Leanza, Cristiana ; Tomolillo, Dario ; Luceri, Cristina ; Oliva, Alessandra ; Servidio, Camilla ; Lorusso, Angela
OBJECTIVES:
Traditional budget impact analysis models, usually based on predefined populations, often fail to capture the complexity of hospital antibiotic use, which is dynamic and often empirical. To address this gap, we developed and applied an adaptable budget impact analysis model based on real-world consumption data of high-cost reserve antibiotics (HCR-ABX), with the objective of projecting their short-term budget impact in a large university hospital over a 3-year horizon.
METHODS:
HCR-ABX with a purchase cost >€100/defined daily doses (DDD) were selected. The model used retrospective hospital pharmacy data (2021-2024) and incorporated national guidelines on multidrug-resistant infections, regulatory/reimbursement updates, and local resistance trends. These inputs were used to define drug-specific annual variation rates applied in the projection scenarios. Future costs were estimated by combining projected consumption (DDD/100 hospitalization days) with the hospital purchase cost per DDD. Three forecast scenarios (base case, lower impact, higher impact) plus a Klebsiella pneumoniae stress-test scenario were modeled.
RESULTS:
Despite approximately stable overall HCR-ABX consumption, a shift toward higher-cost agents was observed. The base-case scenario projected a cumulative expenditure of approximately €10 586 248 over 3 years, with increases driven by meropenem/Vaborbactam and cefiderocol. The lower-impact and higher-impact scenarios estimated €10 062 688 and €11 050 385 €, respectively. The Klebsiella pneumoniae stress-test scenario indicated a total cost of € 11 321 117 (+6.95% vs base-case scenario), emphasizing the potential financial impact of epidemiological shifts.
CONCLUSIONS:
The proposed model provides a pragmatic, adaptable framework to assess the hospital budget impact of HCR-ABX and supports antimicrobial stewardship. The approach is replicable and can be refined through future validation against observed data.
2027-01-01·MICROBIOLOGICAL RESEARCH
The multiple antimicrobial mechanisms mediated by microbial siderophores and their application prospects
Review
作者: Xia, Ting ; Feng, Yingying ; Wu, Yuying ; Zhao, Yaping ; Wu, Xin ; Huang, Zhengyao
Siderophores are low-molecular-weight (<1500 Da) chelaters secreted by microorganisms under iron-limiting and bind ferric ions (Fe³⁺) with high affinity, supporting iron homeostasis, competition, and pathogenicity regulation. They are sythesized through the nonribosomal peptide synthetase (NRPS) and the NRPS-independent (NIS) pathway, and controlled by the Fur (ferric uptake regulator)-dependent regulation, then exported by the major facilitator superfamily (MFS), resistance-nodulation-division (RND), or ATP-binding cassette (ABC) family transport systems. After chelating iron, complexes are recognized by TonB-dependent receptors and transported into cells. Siderophores inhibit competitors by depriving iron, delivering toxic compounds into cells, and regulating virulence via quorum sensing. They also shape microbial community dynamics. Applications include siderophore antibiotic conjugates such as cefiderocol, receptor targeting, and agricultural biocontrol. Challenges remain in receptor redundancy, ecological complexity, and safety, and future work should integrate omics approaches to develop targeted antimicrobial strategies. Ultimately, siderophore-based strategies offer a promising paradigm shift from direct bactericidal action to resource restriction and virulence attenuation, potentially reducing selective pressure for resistance and opening new avenues for sustainable management of infectious diseases and agricultural pests.
2026-12-31·Emerging Microbes & Infections
IS
903B
-mediated
cirA
inactivation confers cefiderocol resistance and adaptive fitness in carbapenem-resistant
Klebsiella pneumoniae
Article
作者: Dai, Xinyue ; Zhao, Chuwen ; Liu, Yang ; Fan, Linping ; Liu, Yuxuan ; Cao, Yun ; Hong, Hanxu
Cefiderocol (FDC) is a last-resort antimicrobial for the treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP). Although cirA inactivation is a recognized mechanism of FDC resistance, whether different forms of cirA disruption influence bacterial adaptation and persistence remains unclear. By analyzing 1,965 publicly available long-read genomes and 480 clinical isolates, we found that cirA loss-of-function mutations were rare (1.1%) but accumulated over time among isolates from China, with four independently emerged cirA-inactivated ST11 isolates identified across distinct phylogenetic branches. Functional characterization of a representative ST11-KL64 clinical isolate showed that IS903B-mediated cirA inactivation conferred high-level FDC resistance (minimum inhibitory concentration, 128 μg/mL), which was reversed by cirA complementation. Functional assays further demonstrated that, unlike complete cirA deletion, IS903B-mediated cirA inactivation enhanced bacterial adaptation under iron-limited conditions, including competitive fitness, plasmid stability, and host-associated survival. Transcriptomic, enzymatic, and genetic analyses supported distinct Fe-S-associated metabolic remodelling in cirA::IS903B, while deletion of sufS attenuated these adaptive phenotypes. Construction of cirA::IS903B derivatives in multiple independent ST11 clinical isolates reproduced these adaptive phenotypes across diverse genetic backgrounds. Together, these findings demonstrate that IS903B-mediated cirA inactivation not only confers high-level FDC resistance but also promotes bacterial adaptation through mechanisms distinct from complete cirA deletion. The combination of resistance, enhanced adaptation, and increased plasmid stability suggests that specific resistance-associated cirA mutations may facilitate the persistence and dissemination of high-risk CRKP clones. Monitoring cirA integrity and IS insertion status may help identify FDC-resistant lineages with increased dissemination potential.
324
项与 硫酸甲苯磺酸头孢德罗 相关的新闻（医药）2026-10-26
THE LANCET Infectious Diseases. Volume 26Number 7
柳叶刀·传染病学26卷 7期
https://www.thelancet.com/journals/laninf/issue/current
Editorial（社论）
1
Key facts about the Bundibugyo virus outbreak
本迪布焦病毒暴发核心事实
The Lancet Infectious Diseases
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p651
Comment（述评）
2
Treatment of multidrug-resistant Gram-negative infections: a stewardship imperative
多重耐药革兰阴性菌感染治疗：抗菌药物管理势在必行
Sarah Kabbani,L Clifford McDonald
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p652
3
Meningococcal disease, meningococcal vaccines, and the recent meningococcal outbreak in Kent, UK
脑膜炎球菌病、脑膜炎球菌疫苗与英国肯特郡近期脑膜炎球菌暴发
Shamez N Ladhani,Caroline Trotter,Ray Borrow,Gayatri Amirthalingam,Mary E Ramsay
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p653
Correspondence（读者来信）
4
Actionable sexual health education for HIV and STI prevention among LGBTQ+ youth in the USA
面向美国性少数青年、可落地实施的艾滋病与性传播疾病预防性健康教育
Jonah Segil,Matthew J Mimiaga
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e268
5
Effectiveness of the BNT162b2 LP.8.1-adapted SARS-CoV-2 vaccine against COVID-19-associated hospitalisation and death: a Danish nationwide cohort study
适配LP.8.1变异株的BNT162b2新冠疫苗预防新冠相关住院与死亡的有效性：丹麦全国队列研究
Christian Holm Hansen,Bolette Soborg,Morten Rasmussen,Ida Rask Moustsen-Helms,Palle Valentiner-Branth
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e269
6
Andes virus on a cruise ship: person-to-person transmission and an empty pipeline
游轮安第斯病毒疫情：人传人传播与药物储备空白
Oriol Mitjà
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e271
7
Bundibugyo Ebola: why preparedness still fails at the point of detection
本迪布焦埃博拉病毒：为何疫情初筛阶段防控体系仍存在短板
Thirumalaisamy P Velavan,Peter G Kremsner,Francine Ntoumi
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e273
8
Cross-border transmission of Ebola virus disease caused by Bundibugyo virus into Uganda, 2026
2026年本迪布焦埃博拉病毒病跨境传入乌干达疫情
Henry Kyobe Bosa,Misaki Wayengera,Atek Kagirita,Bernard Lubwama,Allan Muruta,Susan Nabadda,Andrew Nsawotebba,Charles Olaro,Diana Atwine,Jane Ruth Aceng
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e275
9
Bundibugyo virus disease outbreak in DR Congo: current trajectory and potential risk for a Pandemic Emergency
刚果民主共和国本迪布焦病毒病暴发：当前流行态势及构成国际关注突发公共卫生事件潜在风险
Marie Roseline Belizaire,Dick Chamla,Mohamed Janabi
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e277
10
Estimation of the Ebola outbreak size in the Democratic Republic of the Congo
刚果民主共和国埃博拉疫情规模估算
Ruth McCabe,Lennox Ebbarnezh,Solome Okware,Richard Fotsing,Etien Koua,Paul Mbaka,Adelard Lofungola,Dav M Ebengo,Placide K Mbala,Tania T Bishola,Christian M Ibolobolo,Herman M Matondo,Jean-Clement M Sibo,Sabine L van Elsland,Martina McMenamin,Neil M Ferguson,Olivier le Polain de Waroux,Anne Cori
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e279
Corrections（勘误）
11
Correction to Lancet Infect Dis 2020; 20: 1204–14
《柳叶刀·传染病》2020年；20卷：1204–14页勘误
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
12
Correction to Lancet Infect Dis 2023; 23: 1370–82
《柳叶刀·传染病》2023年；23卷：1370–82页勘误
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
13
Correction to Lancet Infect Dis 2024; 24: 775–82
《柳叶刀·传染病》2024年；24卷：775–82页勘误
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
14
Correction to Lancet Infect Dis 2026; 26: 343–61
《柳叶刀·传染病》2026年；26卷：343–61页勘误
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
15
Correction to Lancet Infect Dis 2025; published online March 18. https://doi.org/10.1016/S1473-3099(26)00059-9
《柳叶刀·传染病》2025年在线发表勘误，2025年3月18日
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
16
Correction to Lancet Infect Dis 2026; published online March 23. https://doi.org/10.1016/S1473-3099(26)00058-7
《柳叶刀·传染病》2026年在线发表勘误，2026年3月23日
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
17
Correction to Lancet Infect Dis 2026; published online March 31. https://doi.org/10.1016/S1473-3099(26)00063-0
《柳叶刀·传染病》2026年在线发表勘误，2026年3月31日
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e281
18
Correction to Lancet Infect Dis 2026; published online April 17. https://doi.org/10.1016/S1473-3099(26)00144-1
《柳叶刀·传染病》2026年在线发表勘误，2026年4月17日
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e282
19
Correction to Lancet Infect Dis 2026; published online April 28. https://doi.org/10.1016/S1473-3099(26)00137-4
《柳叶刀·传染病》2026年在线发表勘误，2026年4月28日
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e282
Newsdesk（新闻瞭望）
20
Hantavirus outbreak on cruise ship kills three
游轮汉坦病毒疫情致3人死亡
Tony Kirby
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e283
21
New WHO prequalifications signal hope for malaria
世卫组织新增预认证药品为疟疾防治带来希望
Sanjeet Bagcchi
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e284
22
New partnership to support TB vaccine implementation
全新合作项目助力结核病疫苗落地推广
Manjulika Das
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e285
23
Updated Global Action Plan on Antimicrobial Resistance
新版全球抗微生物药物耐药性行动计划
Timothy Jesudason
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e286
24
Update on the Ebola virus outbreak in DR Congo
刚果民主共和国埃博拉病毒疫情最新进展
Talha Burki
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e287
25
Research in brief
研究简报
Priya Venkatesan
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e288
Obituary（讣告）
26
Dame Bridget Ogilvie
布里吉特·奥格尔维女爵士
Udani Samarasekera
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p656
Profile（人物专访）
27
Sabiha Essack—helping Africa lead the fight against AMR
萨比哈·埃萨克——助力非洲主导抗微生物耐药性攻坚
Tony Kirby
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p657
Media Watch（媒体观察）
Film（影视）
28
Challenging the stigma around leprosy
消除麻风病相关社会污名
Sanjeet Bagcchi
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p658
Articles（论著）
29
Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study
新一代抗生素时代美国难治性耐药革兰阴性菌感染患者生存趋势：一项回顾性队列研究
Morgan K Walker,Christina Yek,Sadia Sarzynski,Sarah Warner,Anthony D Harris,Jonathan D Baghdadi,Katherine E Goodman,John H Powers III,Michael Klompas,Chanu Rhee,Bruce Swihart,Sameer S Kadrifor the NIH Antimicrobial Resistance Outcomes Research Initiative (NIH-ARORI)
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p659
30
Development and validation of the AURIS score for predicting candidaemia in Candidozyma auris-colonised patients in the intensive care unit: a bicentric retrospective cohort study
重症监护室耳念珠菌定植患者念珠菌血症预测AURIS评分构建与验证：双中心回顾队列研究
Victor Garcia-Bustos,Francesc Puchades,Fernando Alonso-Ecenarro,Marta Dafne Cabanero-Navalon,Alba Ruiz-Gaitán,Javier Pemán,Miguel Salavert,María Tasias,Eva Calabuig,Remedio Guna,Carolina Ferrer-Gómez,María Pilar Ortega-García,Vicente Abril
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p671
31
Double-dose azithromycin mass drug administration, facial cleanliness, and fly control measures for trachoma control in Oromia, Ethiopia (Stronger SAFE): a cluster-randomised controlled trial
埃塞俄比亚奥罗米亚地区双倍剂量阿奇霉素群体给药、面部清洁与灭蝇综合沙眼防控方案（强化SAFE策略）：整群随机对照试验
Anna Last,Oumer Shafi Abdurahman,Katie Greenland,Ailie Robinson,Edao Sinba Etu,Robert Butcher,Meseret Guye,Demitu Legesse,Kedir Temam Nuri,Gemeda Shuka,Munira Haji-Mohammed Yusuf,Gaddisa Dheressa,Gebeyehu Dumessa,Haile Abera,Mesfin Bekele,Melese Akalu,Mesfin Tadesse,Dereje Adugna Kumsa,Fikre Seife Gebretsadik,Claire Collin,Alexandra Czerniewska,Bart Versteeg,Esmael Habtamu,Sarity Dodson,Aida Abashawl,Wondu Alemayehu,Anthony W Solomon,Helen A Weiss,James G Logan,David Macleod,Matthew J Burton
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p680
32
Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial
无钩虫感染健康成人接种吸附于氢氧化铝佐剂的Na-GST-1疫苗联合不同Toll样受体激动剂的人体可控感染模型Ⅱ期双盲随机对照试验（美国）
Caroline K DiRosato,Elissa M Malkin,Sean M Lee,Guacyara Erwin,Lara Hoeweler,Larissa Scholte,Maria Elena Bottazzi,David I Pritchard,Peter J Hotez,Jeffrey M Bethony,David J Diemert
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p692
33
Post-discharge sequelae of Lassa fever survivors in Nigeria: an analysis of the LASCOPE prospective cohort
尼日利亚拉沙热幸存者出院后远期后遗症分析：LASCOPE前瞻性队列研究
Eva Guichard,Sylvain Juchet,Ijeoma Chukwudumebi Etafo,Béatrice Serra,Delphine Gabillard,Chukwuyem Abejegah,Abiodun Tolani Abidoye,Bimpe Oyegunle,Benjamin Séri,Alexandre Duvignaud,Jackson Katembo Vihundira,Denis Malvy,Marion Bérerd-Camara,Nelson Akinola Adedosu,Ayeni Olufunke Gbenga,Liasu Adeagbo Ahmed,Oladele Oluwafemi Ayodeji,Marie Jaspard
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p705
34
Evaluating dengue transmission dynamics in an endemic urban setting in Viet Nam: an index-household contact cohort study
越南登革热流行城区传播动力学评估：索引病例-家庭接触者队列研究
Lucy Masdin,James Ashall,Mai Kim Huynh,Joseph Biggs,Jody Phelan,Sonal Shah,Lien Thuy Le,Trieu Bao Nguyen,Hung Thai Do,Hien Anh Thi Nguyen,Thuy Thi Thu Nguyen,Duc Anh Dang,Chihiro Iwasaki,Michiko Toizumi,Marnix Van Loock,Guillermo Herrera-Taracena,Leen Vijgen,Freya Rasschaert,Liesbeth Van Wesenbeeck,Julius Clemence Hafalla,Oliver J Brady,Lay-Myint Yoshida,Stéphane Hué,Martin L Hibberd
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p714
35
Optimising DTwP-containing vaccine infant immunisation schedules in Uganda and Nepal (OptImms): two open-label, non-inferiority, randomised controlled trials
乌干达、尼泊尔含无细胞百日咳疫苗婴儿免疫程序优化研究（OptImms）：两项开放标签非劣效随机对照试验
Sanjeev M Bijukchhe,Natalie G Marchevsky,Freddie Kibengo,Arun K Sharma,Ruby Basi,Liberty Cantrell,Sachi Chuke,Benjamin Curtis,Dimitri A Diavatopoulos,Agnes Eordogh,Madhav C Gautam,Meeru Gurung,Gerco den Hartog,Hari P Kattel,Samir KC,Dominic Kelly,Sarah Kelly,Grace Li,Pratistha Maskey,Ella Morey,Yama F Mujadidi,Dora J Mulondo,Tryphena Nareeba,Mary Nyantaro,Anil R Ojha,Bhishma Pokhrel,Shristy Rajkarnikar,Andrew Roberts,Sonu Shrestha,Gaby Smits,Surya B Thapa,Fiona Van der Klis,Merryn Voysey,Sudha Basnet,Alison M Elliott,Xinxue Liu,Shrijana Shrestha,Andrew J Pollardon behalf of the OptImms Nepal and Uganda teams
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p726
36
Safety, tolerability, and immunogenicity of a 31-valent pneumococcal conjugate vaccine (VAX-31) in healthy adults aged 50 years and older from the USA: a phase 1/2, double-blinded, active-controlled, parallel-group, dose-finding randomised clinical trial
美国50岁及以上健康成人31价肺炎球菌结合疫苗（VAX-31）安全性、耐受性与免疫原性Ⅰ/Ⅱ期双盲阳性对照平行分组剂量爬坡随机临床试验
James Wassil,Jeff Fairman,Carlos A Fierro,James Clark,Sean Bennett,Derek Johnson,Qin Jiang,Thi-Sau Migone,Alexandra Paschenko,Jakub K Simon,Steve Lamola,Maggie Sisti
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：p739
Review（综述）
37
Accelerating research and development of new vaccines against tuberculosis: 5-year progress on the global roadmap
加速新型结核病疫苗研发：全球路线图五年进展总结
Elly van Riet,Björn Corleis,Birgitte K Giersing,Mark Hatherill,Erlina Burhan,Waasila Jassat,Richard G White,David Lewinsohn,Frank Cobelens
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e289
38
Best practice guidelines for viral hepatitis service delivery in prisons
监狱病毒性肝炎规范化诊疗最佳实践指南
Yumi Sheehan,Akhil Garg,Julia Sheehan,Nonso Maduka,Frederick L Altice,Filipa Alves da Costa,Sean Cox,Ahmed M Elsharkawy,Ehab Salah,Mark Stoové,Lara Tavoschi,Alexander J Thompson,Karla Thornton,Andrew R Lloyd,Joaquín Cabezas,Matthew J Akiyama,Nadine Kronfli
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e302
Personal View（个人观点）
39
Post-tuberculosis lung disease: a case definition for use in research studies
结核后肺病：适用于科研的病例定义标准
Gregory P Bisson,Brian Allwood,Anthony Byrne,Gunar Günther,Celso Khosa,Neelima Navuluri,Rebecca Nightingale,Ingrid Schoeman,Marieke M van der Zalm,Jamilah Meghji,Sara Auld
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e315
Grand Round（大查房）
40
Management of critical illness in an adolescent caused by highly pathogenic avian influenza A(H5N1) virus infection in British Columbia, Canada
加拿大不列颠哥伦比亚省高致病性甲型H5N1禽流感病毒感染青少年危重症诊疗
Elspeth MacBain,Ashraf Znait,Linda Edwards,Agatha Jassem,Vilte E Barakauskas,Kevin C Harris,Sarah Lohrenz,Sareh Zahedieh,Nathalie Bastien,Charlene Ranadheera,Cherry Mammen,Roxana Azma,Audi Setiadi,Jonathan H Rayment,Nicolas Mourad,Ryaan El-Andari,Timothy M Uyeki,Lynne Li,Ashley Roberts,Muhieldin A Muhieldin,David M Goldfarb
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e326
Clinical Picture（临床图鉴）
41
Disseminated herpes zoster with hepatic necrosis in a patient with newly diagnosed HIV
初诊艾滋病患者播散性带状疱疹合并肝坏死
Shinya Hasegawa,Frida Teran-Garza,Jeffery L Meier
The Lancet Infectious Diseases. Jul 2026，Vol 26(7)：e335
THE LANCET Infectious Diseases. Volume 26Number 8
柳叶刀·传染病学26卷 8期
https://www.thelancet.com/journals/laninf/issue/current
Editorial（社论）
1
Our twenty-five year journey
二十五载发展历程
The Lancet Infectious Diseases
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p751
Comment（述评）
2
Sense and susceptibility: predicting influenza dynamics from immune landscapes
感知与易感性：基于免疫图谱预测流感流行动态
C Jessica E Metcalf,Wakinyan Benhamou,Oliver G Spacey,Jasmine Wang
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p752
3
New chapter in rabies vaccine development
狂犬病疫苗研发迈入新阶段
Leo G Visser
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p753
4
Clinical trial priorities, adaptive strategies, and equitable partnerships for the Bundibugyo Ebola outbreak
本迪布焦埃博拉疫情的临床试验重点、适应性策略与公平合作模式
Jean B Nachega,Olivier Tshiani Mbaya,Sabue Mulangu,Morenike Oluwatoyin Folayan,Nicaise Ndembi,Francine Ntoumi,Edward J Mills,Salim S Abdool Karim,Alimuddin Zumla,Jean-Jacques Muyembe-Tamfum
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p755
5
Bundibugyo Ebola in DR Congo and Uganda: community-centred response must be operational, not rhetorical
刚果民主共和国与乌干达本迪布焦埃博拉疫情：以社区为核心的防控重在落地而非空谈
Placide Mbala-Kingebeni,Yap Boum,Mosoka P Fallah,Barthalomew Wilson,Marie-Roseline Belizaire,Nicole A Hoff,Armand Sprecher,Lisa E Hensley,Jason Kindrachuk,Anne W Rimoin
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p757
6
The Bundibugyo virus disease outbreak: a warning signal for risks to health workers
本迪布焦病毒病暴发：医护人员职业暴露风险预警
Nebiyu Dereje,Yap Boum,Kyeng Mercy,Marie-Roseline Belizaire,Tolbert Nyenswah,Justus Nsio,Pierre Zalagile Akilimali,Atek Kagirita,Ngashi Ngongo,Jean Kaseya
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p759
Correspondence（读者来信）
7
Rapid recruitment for a remote long COVID clinical trial
远程长新冠临床试验受试者快速招募
Julia Moore Vogel
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e268
8
Tuberculosis treatment with early detection
早筛导向的肺结核治疗
Aparna Prakash
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e269
9
The limb-saving power of bedside Gram staining
床旁革兰氏染色的保肢价值
Samadhi Patamatamkul
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e270
10
Keep antibiotics habitable: stewardship as climate mitigation
守护抗生素生态：抗菌药物管理助力环境风险缓解
Giovanni Mori
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e271
11
25 years of antibiotics: from desperate access to precision safety
抗生素应用25年：从迫切可及迈向精准安全
Jinlin Guo,Xinfeng Cai,Mi Zhou
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e272
12
The optimism in front of us
前路可期
Victor Naestholt Dahl
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e273
13
The importance of study volunteers in saving future lives
研究志愿者对守护大众健康的重要意义
Chuen-Yen Lau
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e274
14
Crossing the regulatory and clinical operational valley in antimicrobial resistance: from a start-up's perspective
跨越抗菌耐药领域监管与临床落地鸿沟：初创企业视角
Venu Gopal Jonnalagadda
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e275
15
A new era of hope: the impact of long-acting injectables for individuals ageing with childhood HIV
希望新时代：长效注射药物对儿童期感染HIV老龄患者的作用
Hayley T Berry,Jordan Jones,Richard Lueking,Stephanie E Kirk
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e276
16
A defining clinical moment during the COVID-19 pandemic in Nigeria
尼日利亚新冠疫情中标志性临床事件
Chizaram Onyeaghala
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e277
Corrections（勘误）
17
Correction to Lancet Infect Dis 2026; published online June 2. https://doi.org/10.1016/S1473-3099(26)00194-5
《柳叶刀·传染病》2026年6月2日在线刊发文章勘误，文献doi：10.1016/S1473-3099(26)00194-5
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e278
18
Correction to Lancet Infect Dis 2026; published online June 3. https://doi.org/10.1016/S1473-3099(26)00285-9
《柳叶刀·传染病》2026年6月3日在线刊发文章勘误，文献doi：10.1016/S1473-3099(26)00285-9
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e278
Newsdesk（新闻资讯）
19
Indigenous Australians see surge in diphtheria cases
澳大利亚原住民白喉病例激增
Tony Kirby
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e279
20
Trials of medical countermeasures to begin in DR Congo
刚果民主共和国启动医学应对手段临床试验
Esther Nakkazi
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e280
21
Rollout of lenacapavir begins in South Africa
南非正式推广莱那卡韦
Ed Holt
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e281
22
Cold-chain vehicles to support vaccination in Ecuador
冷链运输车辆助力厄瓜多尔疫苗接种工作
Sanjeet Bagcchi
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e282
23
2026 High-Level Meeting on HIV/AIDS
2026年艾滋病高级别会议
Talha Burki
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e283
24
Research in brief
科研快讯
Priya Venkatesan
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e284
Obituary（讣告）
25
Edward Pesanti
爱德华·佩桑蒂
Udani Samarasekera
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p762
Profile（人物专访）
26
Krutika Kuppalli—containing infectious disease outbreaks
克鲁蒂卡·库帕利：防控传染病疫情
Udana Samarasekera
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p763
27
Troy Grennan—getting anal cancer the attention it deserves
特洛伊·格伦南：推动肛门癌获得应有重视
Tony Kirby
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p764
Media Watch（媒体瞭望）
Book（书评）
28
The market for pox remedies
天花治疗药物市场
Talha Burki
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p765
Articles（论著）
29
Measuring population immunity against influenza using individual antibody titres: a multicountry, retrospective observational study
基于个体抗体滴度评估人群流感免疫水平：多国回顾性观察研究
Weijia Xiong,Xiaotong Huang,Tran Thi Nhu Thao,Nguyen Thi Le Thanh,Liping Peng,Ranawaka A P M Perera,Vicky J Fang,Bingyi Yang,Sook-San Wong,Nancy H L Leung,Sheena G Sullivan,Dennis K M Ip,Malik Peiris,Ted M Ross,Maciej F Boni,Benjamin J Cowling,Tim K Tsang
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p766
30
Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial
新加坡高频、低频接种青年人群中，高剂量重组流感疫苗对比标准剂量鸡胚培养、细胞培养流感疫苗的免疫原性：单中心随机对照双盲4期临床试验
Sheena G Sullivan,Xuan Ying Poh,Stephany Sanchez-Ovando,A Jessica Hadiprodjo,Louise Carolan,Yi Qing Chin,Suma Rao,Stephanie Sutjipto,Joseph Lim,Desiree Anthony,Sapna P Sadarangani,Ian G Barr,Barnaby Young,Annette Fox
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p778
31
Immunogenicity, reactogenicity, and safety of a reduced-interval 4CMenB primary immunisation schedule in UK infants: a multicentre, open-label, assessor-blinded, phase 4 randomised controlled trial
英国婴儿缩短间隔4CMenB基础免疫程序的免疫原性、不良反应与安全性：多中心开放标签、评估者盲法4期随机对照试验
Natasha Thorn,Zsofia Danos,Nick J Andrews,Natalina Sutton,Katrina Cathie,Daniel Owens,Dominic Kelly,Fiona Shackley,Tim Scorrer,Charlotte Lea,Andrew Collinson,Thahmena Miah,Jonathan Lewis-Bridgeman,Jennifer Pearce,Ray Borrow,Jennifer Louth,Abigail Bell,Shamez N Ladhani,Paul T Heath
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p793
32
Real-world effectiveness of 20-valent pneumococcal conjugate vaccine against all-cause outcomes among Medicare beneficiaries aged 65 years and older in the USA: a retrospective cohort study
美国65岁及以上医保参保人群中20价肺炎球菌结合疫苗针对全因结局在现实中的保护效力：回顾性队列研究
Amanda C Miles,Jelena Vojicic,Paula Peyrani,Summer Rosenstock,Huihua Li,Jeffrey T Vietri,Qi Yan,Alison E Randall,Xin Zhao,Wencheng Zhu,Bobby Zhao,Anan Zhou,Luis Jodar,Bradford D Gessner,Christian Theilacker,Jennifer C Moïsi,Paul Balmer,Lindsay R Grant,Alejandro Cane
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p807
33
Durability of doxycycline effectiveness against gonorrhoea after implementation of post-exposure prophylaxis in southern California, USA: a retrospective, test-negative, observational study
美国南加州开展暴露后预防后多西环素抗淋病疗效的持续性：回顾性病例阴性观察研究
Matan Yechezkel,David Helekal,Banshri Kapadia,Vennis Hong,Magdalena E Pomichowski,Iris Anne C Reyes,Gregg S Davis,Nicola F Müller,Yonatan H Grad,Sara Y Tartof,Joseph A Lewnard
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p819
34
Duration and association with protection of NANP-repeat-specific and C-terminus-specific anti-circumsporozoite protein IgG responses following RTS,S/AS01E vaccination: an observational ancillary immunological study of a phase 3 clinical trial
接种RTS,S/AS01E疫苗后，环子孢子蛋白NANP重复序列、C端特异性IgG应答持续时间及其与保护力的关联：3期临床试验配套免疫观察研究
Maria Lara-Escandell,Lina Sánchez,Dídac Macià,Chenjerai Jairoce,Maxmillian Mpina,Hermann Sorgho,Selidji Todagbe Agnandji,David Dosoo,Ben Gyan,Marta Vidal,Alfons Jiménez,Robert Andrew Mitchell,Daniel Medina-Expósito,Laura Puyol,Rebeca Santano,Sheetij Dutta,Seth Owusu-Agyei,Kwaku Poku Asante,Halidou Tinto,Pedro Aide,Augusto Nhabomba,Benjamin Mordmüeller,Claudia Daubenberger,Ruth Aguilar,John Waitumbi,Gemma Moncunill,Carlota Dobaño
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p832
35
Safety and immunogenicity of a single-dose adenovirus-vectored rabies vaccine over 1 year in adults and children in Tanzania: interim data from an ongoing, partly randomised, controlled, phase 1b/2 trial
坦桑尼亚成人与儿童单次腺病毒载体狂犬病疫苗接种1年期安全性及免疫原性：一项正在开展的部分随机对照1b/2期临床试验中期结果
Adam J Ritchie,Omary Hassan,Nsiande Urasa,Paschal A Apanga,Rinter Kimathi,Wilmina F Kalinga,Ivanny M Mtaka,Reward G Lyimo,Moshi Moshi Shabani,Francisco Orliacq,Adam Berg,ZhiQuan Xiang,Saumu Ahmed,Thabit Athuman,Hildegund C J Ertl,Ally Olotu,Alexander D Douglason behalf of the RAB002 study team
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p843
36
Diagnostic and prognostic accuracy of the Mycobacterium tuberculosis host response 3-gene cartridge among tuberculosis household contacts in Mozambique, Tanzania, and Zimbabwe: a prospective, longitudinal, diagnostic and prognostic accuracy cohort study
莫桑比克、坦桑尼亚、津巴布韦结核家庭密切接触者中结核宿主应答三基因检测试剂盒的诊断与预后效能：前瞻性纵向诊断预后队列研究
Leyla Larsson,Ioana Diana Olaru,Anna-Lisa Behnke,Edson T Marambire,Martha Chipinduro,Claire J Calderwood,Denise Banze,Alfred Mfinanga,Celina Nhamuave,Harieth L Mwambola,Kathrin Held,Rishi K Gupta,Lillian T Minja,Celso Khosa,Norbert Heinrich,Katharina Kranzeron behalf of the ERASE-TB consortium
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：p858
Review（综述）
37
Methodological quality assessment tool for observational studies comparing treatment effectiveness in infectious diseases: a Delphi consensus and application to studies on bloodstream infections due to carbapenem-resistant Enterobacterales
传染病疗效对比观察性研究方法学质量评价工具：德尔菲共识构建及耐碳青霉烯肠杆菌科菌血流感染研究应用
Giulia Zumbo,Martina Beltrami,Jose M Bravo-Ferrer,Belén Gutiérrez-Gutiérrez,Jesús Rodríguez-Bañothe ASSURE-ID group
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e285
38
Leptospirosis—clinical review and updates on therapeutics
钩端螺旋体病临床综述与治疗新进展
Nathaniel Lee,Takeshi Tanaka,Nobuo Koizumi,Charles Coughlan,Ana Ria Sayo,Koya Ariyoshi,Tansy Edwards,Chris Smith,Robin Bailey
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e294
Personal View（个人观点）
39
Transitioning to people-centred antimicrobial resistance surveillance
向以人为本的抗菌药物耐药监测模式转型
Direk Limmathurotsakul,Raheelah Ahmad,Elizabeth A Ashley,Rifat Atun,Rogier H van Doorn,Jyoti Joshi,Souha S Kanj,Janet Midega,Mirfin Mpundu,Paul Turner,Kamini Walia,Sharon J Peacock,Nicholas A Feaseyand the Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC)
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e308
40
The looming crisis of bedaquiline-resistant tuberculosis and a promising way forward
贝达喹啉耐药肺结核危机迫近与可行解决路径
Pauline Howell,Jonathan Stillo,Anja Reuter,Tendai Nkomo,Carole D Mitnick,Lorenzo Guglielmetti,Kelly Curran,Richard E Chaisson,Jennifer Furin
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e314
Clinical Picture（临床图鉴）
41
Ignatzschineria larvae and Staphylococcus aureus bacteraemia secondary to cutaneous myiasis of the face
面部皮肤蝇蛆病继发伊格纳茨菌幼虫与金黄色葡萄球菌菌血症
Clive Martin Rodrigues,Jonathan Youngs,Anjaneya Bapat,Callan Strydom
The Lancet Infectious Diseases. Aug 2026，Vol 26(8)：e319
THE LANCET Infectious Diseases. Volume 26Number 9
柳叶刀·传染病学 26卷 9期
https://www.thelancet.com/journals/laninf/issue/current
Editorial（社论）
1
Oral carbapenem—a double‑edged sword?
口服碳青霉烯类药物：一把双刃剑？
The Lancet Infectious Diseases
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p871
Comment（述评）
2
Non‑sputum testing: an incomplete bridge across the tuberculosis diagnostic gap
非痰标本检测：弥合结核病诊断缺口尚不完美的桥梁
Adrienne E Shapiro
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p872
3
Beyond vaccines: closing the critical gap in diagnostics and therapeutics for outbreak response
疫苗之外：补齐疫情应对中诊断与治疗领域的关键短板
Tedros Adhanom Ghebreyesus,Jean Kaseya,Chikwe Ihekweazu,Vasee Moorthy,Mosoka Fallah,Shanelle Hall,Sylvie Briand
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p873
4
Reconsidering the rVSVΔG‑ZEBOV‑GP vaccine during the 2026 Bundibugyo virus outbreak
2026年本迪布焦病毒暴发期间对rVSVΔG‑ZEBOV‑GP疫苗的再思考
Krutika Kuppalli,Richard Lokudu,Andrew S Azman,Armand Sprecher,Gaston Musemakweli Komanda,Iza Ciglenecki,Manuel Albela,Deby Mukendi,Yap Boum,Jean B Nachega,Placide Mbala,Jean‑Jacques Muyembe‑Tamfum
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p875
Correspondence（通信）
5
Seasonal influenza versus COVID‑19 hospitalisation risk during the 2025–26 influenza season
2025‑2026流感季季节性流感与新型冠状病毒感染住院风险对比
Yan Xie,Taeyoung Choi,Ziyad Al‑Aly
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e321
6
Cefiderocol heteroresistance in NDM Enterobacterales
NDM阳性肠杆菌目细菌对头孢地尔的异质性耐药
Tugba Ozturk,Sarah Lohsen,Sarah W Satola,David S Weiss
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e323
7
Diagnostic performance of RADIONE for diagnosis of BDBV
RADIONE检测用于本迪布焦病毒的诊断效能
Tony Wawina‑Bokalanga,Adrienne Amuri‑Aziza,Koen Vercauteren,Daniel Mukadi‑Bamuleka,Christian Ngandu,Jason Kindrachuk,Pierre Akilimali,Jean‑Jacques Muyembe‑Tamfum,Placide Mbala‑Kingebenithe Ebola Research and Response Team
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e324
8
Real‑time epidemic intelligence in a public health emergency: the 2026 Bundibugyo virus outbreak
突发公共卫生事件下的实时疫情情报：2026年本迪布焦病毒暴发
Onesime Mbulayi,Pierre Akilimali,Ciara Judge,Bernardo Gutierrez,Patrick Mulu,Chistian M Ibolobolo,Jean‑Clement Sibo,Rossy Nkwele wa Nkwele,Matondo M Hermann,Leader Lawanga Ontshick,Daniel Mukadi,Benjamin Kanku,Eric Katanga,Kyeng Mercy,Joel Kosianza,Brian Ajong,Michel Muteba,Tania Bishola Tshitenge,Eddy Lusamaki,Romain Goldenberg,Linus Bengtsson,Ellie Bourgikos,Joseph L‑H Tsui,Cathal Mills,Moritz U G Kraemer,Samuel V Scarpino,Christian Ngandu,Dieudonne Mwamba Kazadi,Etien Koua,Olivier le Polain de Waroux,Placide Mbala‑Kingebeni,Dav M Ebengo
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e326
9
SARS‑CoV‑2 BA.3.2.2 is more evasive of neutralisation by plasma from young children
新冠病毒BA.3.2.2变异株更易逃逸幼儿血浆的中和作用
Madeline Wu,Hsiang Hong,Yicheng Guo,Kristin Daniel,Ryan Hisner,Marc C Johnson,Aubree Gordon,David D Ho,Ian A Mellis
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e328
10
Pseudovirus‑based analysis of host cell entry and vaccine‑induced neutralisation of Bundibugyo virus
基于假病毒分析本迪布焦病毒的宿主细胞入侵及疫苗诱导的中和效应
Markus Hoffmann,Aparna Shandheep,Andreas Pavlou,Katharina Rahmel‑Stein,My Linh Ly,Nianzhen Chen,Nicole Moor,Anna‑Sophie Moldenhauer,Christian Drosten,Ulrich Kalinke,Marylyn Martina Addo,Stefan Pöhlmann
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e330
11
Congolese hospital staff cohort admitted with infectious symptoms in the setting of the Bundibugyo virus outbreak, April and May 2026, Bunia, DR Congo
2026年4‑5月刚果（金）布尼亚，本迪布焦病毒暴发期间因感染症状入院的刚果医护人员队列
Patrick LaRochelle,Melinda McKnight,Ufoymungo Ucama Patrick,Musungufu Ambitapio Davin
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e332
Corrections（勘误）
12
Correction to Lancet Infect Dis 2020; 20: 37–59
勘误：Lancet Infect Dis 2020; 20: 37‑59
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e335
13
Correction to Lancet Infect Dis 2020; 20: 60–79
勘误：Lancet Infect Dis 2020; 20: 60‑79
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e335
14
Correction to Lancet Infect Dis 2026; published online June 30. https://doi.org/10.1016/S1473‑3099(26)00256‑2
勘误：Lancet Infect Dis 2026，6月30日在线发表。https://doi.org/10.1016/S1473‑3099(26)00256‑2
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e335
Newsdesk（新闻）
15
Sri Lanka battles major dengue outbreak
斯里兰卡应对登革热大规模暴发
Samaan Lateef
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e336
16
USA to end support of South Africa's HIV programmes
美国将终止对南非艾滋病项目的资助
Ed Holt
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e337
17
First rapid nucleic acid test for Bundibugyo virus
首款本迪布焦病毒快速核酸检测问世
Priya Venkatesan
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e338
18
New UN resolution links NTDs to human rights
联合国新决议将被忽视的热带病与人权相关联
Timothy Jesudason
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e339
19
Enrolment begins in the EBO‑PEP trial in DRC
刚果（金）EBO‑PEP临床试验启动受试者入组
Talha Burki
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e340
20
Research in brief
研究简报
Priya Venkatesan
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e341
Obituary（讣告）
21
Clarence James Peters
克拉伦斯·詹姆斯·彼得斯
Udani Samarasekera
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p878
Profile（人物专访）
22
Aalisha Sahukhan—strengthening public health responses
阿丽莎·萨胡坎——强化公共卫生应急处置能力
Tony Kirby
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p879
Media Watch（媒体观察）
Theatre（书评·戏剧）
23
Pride and solidarity
自豪与团结
Marco De Ambrogi
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p880
Articles（论著）
24
Expanding Xpert MTB/RIF Ultra and lateral flow urine lipoarabinomannan testing for diagnosis of tuberculosis among adults living with HIV admitted to hospitals in Tanzania and Mozambique (EXULTANT): a randomised controlled trial
在坦桑尼亚与莫桑比克住院HIV感染成人中推广Xpert MTB/RIF Ultra及尿脂阿拉伯甘露聚糖侧流检测用于结核病诊断（EXULTANT）：一项随机对照试验
Marta Cossa,Robert Ndege,Bindiya Meggi,Chacha Mangu,Vinzeigh Leukes,Issa Sabi,Celso Khosa,Bernard Kivuma,Dinis Nguenha,Friedrich Riess,Carlos Fernández‑Escobar,Laura de la Torre‑Perez,Patricia Manjate,Maja Weisser,Antonio Machiana,Craysophy Zachariah,Elisa Tagliani,Joanna Ehrlich,Julia Buech,Claudia Schacht,Sergi Sanz,Sunita Singh,Dorcas Mnzava,Samuel G Schumacher,Helen Cox,Leslie Scott,Nyanda Ntinginya,Katharina Kranzer,Morten Ruhwald,Adam Penn‑Nicholson,Alberto L Garcia‑Basteiroon behalf of the TB‑CAPT Consortium
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p881
25
Post‑mortem characterisation of pathogen‑specific causes of infection‑related deaths in African and south Asian neonates: a prospective, observational, multicentre study
非洲与南亚新生儿感染相关死亡的病原体特异性死因尸检分析：一项前瞻性、观察性多中心研究
Muntasir Alam,Kyu Han Lee,Vicky Baillie,Sana Mahtab,Afruna Rahman,Atique Iqbal Chowdhury,Julius Ojulong,Nega Assefa,Lola Madrid,Fentabil Getnet,Ayantu Mekonnen,Dickens Onyango,Victor Akelo,Florence Murila,Magdalene Kuria,Aggrey Igunza,Samba O Sow,Karen L Kotloff,Milagritos D Tapia,Adama Mamby Keita,Jane Juma,Inacio Mandomando,Marcelino Garrine,Rosauro Varo,Milton Kincardett,Ikechukwu Ogbuanu,Kazi Munisul Islam,Sulaiman Sannoh,Ima‑Abasi Bassey,Ejikeme Chukwuka Oham,Nelesh P Govender,Sithembiso Velaphi,Anthony Scott,Portia Mutevedzi,Beth Tippett Barr,Shams El Arifeen,Emily S Gurley,Quique Bassat,Cynthia G Whitney,Shabir A Madhithe CHAMPS Consortium
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p894
26
Performance of five mpox antigen‑based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study
5项猴痘抗原快速检测用于刚果（金）金沙萨省疑似猴痘患者皮损拭子样本的诊断效能：一项诊断准确性研究
Hugo Kavunga‑Membo,Hanesh Fru Chi,Devy M Emperador,Hugues Mirimo,Elie Ishara‑Nshombo,Marithe Mukoka,Raphael Lumembe,Michael Otieno,Mireille Muloki,Jean‑Claude Makangara‑Cigolo,Eddy Kinganda‑Lusamaki,Tony Wawina‑Bokalanga,Camille Escadafal,Kenneth Adea,Ana Hoxha,Rosamund F Lewis,Nicksy Gumede,Olga Ntumba‑Tshitenge,Richard Fotsing,Isabella Eckerle,Daniel Mukadi‑Bamuleka,Placide Mbala‑Kigenbeni,Emmanuel Agogo,Lorenzo Subissi
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p906
27
Immunogenicity and safety of a dose‑sparing inactivated poliovirus vaccine in infants in India: a phase 2/3, double‑blind, randomised controlled trial
印度婴儿减量接种灭活脊髓灰质炎疫苗的免疫原性与安全性：一项2/3期双盲随机对照试验
Prasad S Kulkarni,Sajjad A Desai,Suman Kanungo,Shanta Dutta,Madhu Gupta,Bheemisetty Srinivasa Chakravarthy,Sonali Palkar,Sushma Save,Renuka Munshi,Pradeep Nanjappa,Vijai Anand Babu Bangi,Sandeep Kumar Panigrahi,Sandesh Bharati,Parikshit Tyagi,Sunil Gairola,Jagdish K Zade,Sambhaji S Pisal,Rajeev M Dhere,Cyrus S Poonawalla,Anirudha Vyankatesh Poteyon behalf of the IPV‑01 Study Group
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p915
28
Sustained and indirect effects of PCV10 reduced‑dose schedules on pneumococcal carriage in Viet Nam: a long‑term follow‑up of a cluster‑randomised controlled trial
越南PCV10减量免疫程序对肺炎链球菌携带的持续及间接效应：一项整群随机对照试验的长期随访
Billy J Quilty,Michiko Toizumi,Hien Anh Thi Nguyen,Lien Thuy Le,Hoang Huy Le,Chihiro Iwasaki,Mizuki Takegata,Noriko Kitamura,Mohammad Monir Shah,Monica L Nation,Jason Hinds,Kevin van Zandvoort,Belinda D Ortika,Eileen M Dunne,Catherine Satzke,Hung Thai Do,Kim Mulholland,Duc‑Anh Dang,Stefan Flasche,Lay‑Myint Yoshida
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p925
29
Global and regional molecular epidemiology of HIV‑1 during 1990–2024: systematic review, global survey, and analysis of prevalence
1990‑2024年全球及区域HIV‑1分子流行病学：系统综述、全球调研与流行率分析
Ayisha Khalid,Lucy Gettins,Lauren Scullion,Xin Liu,Lily Li Lin Wei,Abednego N Masai,Philippe J Guerin,Kasim Allel,Joris HemelaarGlobal HIV Molecular Epidemiology Collaboration
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p939
30
Maribavir for clinically significant cytomegalovirus infection in haematopoietic cell transplant recipients in Europe: a real‑world multicentre retrospective registry study
马立巴韦治疗欧洲造血细胞移植受者临床意义明确的巨细胞病毒感染：一项多中心真实世界回顾性登记研究
Annalisa Paviglianiti,Per Ljungman,Rafael de la Camara,Gloria Tridello,Juana Schwartz,Nina Knelange,Arancha Bermudez Rodriguez,María Suárez‑Lledó,Johan Maertens,Maria Stamouli,Francis Ayuk,Candela Ceballos,Maria Huguet,Felipe Peña Muñoz,Pablo Granados,Alienor Xhaard,Jurgen Kuball,Chiara Nozzoli,Jan Styczynski,Dina Averbuchon behalf of the Infectious Diseases Working Party of the EBMT
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p956
31
Dihydroartemisinin–piperaquine versus chloroquine for the treatment of uncomplicated Plasmodium vivax malaria with concurrent or delayed high‑dose primaquine in Brazil (Curavivax): an open‑label, single‑centre, randomised clinical trial
巴西伯氨喹同步或延迟大剂量给药前提下，双氢青蒿素哌喹对比氯喹治疗非复杂性间日疟（Curavivax）：开放标签单中心随机临床试验
Djane C Baía‑da‑Silva,Kim Vinícius AmaralC Machado,Amanda Lia RebêloC Rabelo,Antônio AlcirleyC da Silva Balieiro,Antônio S LC Barbosa,Mônica Regina FariasC Costa,Vanderson S Sampaio,Gisely C Melo,Marcia A A Alexandre,Aline C C Alencar,Cristiana T Nascimento,Christiane Maria Prado Jerônimo,Mariana Souza Marcovski,Laila Rowena Albuquerque Barbosa,Cristiane Siqueira Valle,Thaís Alves Amaral Carrilho,JoséLuiz Fernandes Vieira,Marly Marques de Melo,Kelry Mazurega Oliveira Dinelly,Aretha Gomes Omena,José Diego Brito‑Sousa,Gilce Alves Barreiros,Yasmin Vieira Rocha,Aristóteles Comte Alencar Filho,Quique Bassat,Maria das Graças C Alecrim,André M Siqueira,Marcus V G Lacerda
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：p965
Review（综述）
32
The impact of clinical metagenomic testing on patient management: facts versus fantasy
临床宏基因组检测对患者诊疗的影响：现实与展望
Julianne R Brown,Charles Y Chiu,F Xavier López‑Labrador,Jutte J C de Vries
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e342
33
Artemisinin partial resistance at a crossroads: evidence for continental variation in Plasmodium falciparum clearance phenotypes
青蒿素部分耐药来到十字路口：恶性疟原虫虫体清除表型存在洲际差异的证据
Varun Hosangadi,David A Fidock
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e355
Personal View（个人观点）
34
Time to re‑evaluate combination antifungal therapy for invasive aspergillosis and other invasive mycoses
需重新评估侵袭性曲霉病及其他侵袭性真菌病的抗真菌联合治疗方案
Thomas S Harrison,Thomas J Walsh
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e366
Grand Round（临床病例研讨）
35
Intravenous immunoglobulin treatment for long COVID: a case report of clinical and immunological findings
静脉注射免疫球蛋白治疗长新冠：1例临床及免疫学结果病例报告
Marta Camici,Eva Piano Mortari,Giulia Del Duca,Eleonora Cimini,Valentina Mazzotta,Chiara De Ponte,Ilaria Mastrorosa,Stefania Mazzotta,Carmela Pinnetti,Stefania Notari,Veronica Bordoni,Simona Gili,Giusi Prencipe,Fabrizio Maggi,Rita Carsetti,Enrico Girardi,Andrea Antinori,Chiara Agrati
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e373
Clinical Picture（临床图鉴）
36
Tularaemia after deer exposure in a vehicular collision
车辆碰撞接触鹿后罹患土拉菌病
Henning Gruell,Benedict Steffens,Daniela Jacob,Thorsten Wille,Leonard Poluschkin,Clara Lehmann,Philipp Schommers
The Lancet Infectious Diseases. Sep 2026，Vol 26(9)：e385
THE LANCET Infectious Diseases. Volume 26Number 10
柳叶刀·传染病学 26卷 10期
https://www.thelancet.com/journals/laninf/issue/current
Editorial（社论）
1
Counteracting the rise of antimicrobial resistance in Shigella
遏制志贺菌耐药性上升
The Lancet Infectious Diseases
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p975
Comment（述评）
2
A rifamycin-free regimen for shortened tuberculosis treatment
不含利福霉素类药物的短程结核病治疗方案
Guofang Deng,Liang Fu
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p976
3
Can better oral care reduce non-ventilator hospital-acquired pneumonia?
优化口腔护理能否降低非机械通气患者医院获得性肺炎发生率？
Catia Cilloniz,Michael Klompas
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p977
4
Mpox: virus expansion, evolution, and immune recognition
猴痘：病毒扩散、进化与免疫识别
Jason Kindrachuk,Anne W Rimoin
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p979
5
South Sudan's first 100 days of Bundibugyo Ebola readiness
南苏丹邦迪布焦埃博拉疫情首个百日防控准备工作
Dick Chamla,Marie Roseline Darnycka Belizaire,Arisekola Jinadu,Aggrey Bategereza,Isaias Fernandes,Stella Chunggong,Mohamed Janabi
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p980
Correspondence（读者来信）
6
Antibody evasion and receptor binding of SARS-CoV-2 variants PQ.16.1.1 and RK.1
新冠病毒变异株PQ.16.1.1与RK.1的抗体逃逸及受体结合特性
Peizhuo He,Yunwen Song,Caiwan Guo,Lingling Yu,Yuanling Yu,Fanchong Jian,Fei Shao,Yunlong Cao
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e386
7
Cross-reactive Bundibugyo antibody responses in Guinean survivors of Ebola virus and recipients of rVSVΔG-ZEBOV-GP (Ervebo) in an outbreak setting
疫情背景下几内亚埃博拉幸存者与Ervebo疫苗接种者体内邦迪布焦型埃博拉交叉反应抗体应答
Grace Hood,Joseph Akoi Bore,Dung Nguyen,Weston Struwe,Miles Carroll
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e388
Corrections（勘误）
8
Correction to Lancet Infect Dis 2024; 24: 763
《柳叶刀·传染病学》2024年第24卷763页勘误
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e390
9
Correction to Lancet Infect Dis 2026; published online July 7. [https://doi.org/10.1016/S1473-3099(26)00237-9](https://doi.org/10.1016/S1473-3099(26)00237-9)
《柳叶刀·传染病学》2026年7月7日在线发表文章勘误
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e390
10
Correction to Lancet Infect Dis 2026; 26: 832–42
《柳叶刀·传染病学》2026年第26卷832–842页勘误
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e390
Newsdesk（新闻专栏）
11
US measles elimination status likely to be lost as cases surge
麻疹病例激增，美国或将丧失麻疹消除认证
Tony Kirby
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e391
12
Merck's alimatravir licensing deal receives mixed response
默沙东alimatravir授权合作引发多方不同反响
Ed Holt
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e392
13
WHO updates guidelines for visceral leishmaniasis
世界卫生组织更新内脏利什曼病诊疗指南
Sanjeet Bagcchi
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e393
14
The Global Fund supports malaria response in DR Congo
全球基金助力刚果民主共和国疟疾防控
Manjulika Das
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e394
News（新闻）
15
Infection prevention and control gaps in Pakistan
巴基斯坦感染防控体系存在短板
Talha Burki
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e395
16
Research in brief
研究简讯
Priya Venkatesan
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e396
Obituary（讣告）
17
Bruce Ribner
布鲁斯·里布纳
Udani Samarasekera
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p984
Profile（人物专访）
18
Mahboubeh Hajiabdolbaghi—advancing ID care in Iran
马哈布贝·哈吉阿卜杜勒巴吉——推动伊朗传染病诊疗发展
Tony Kirby
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p985
Media Watch（媒体观察）
Books（书评）
19
Understanding the common cold
解读普通感冒
Emma Fabiani
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p986
Book（书评）
20
Taking on the silent killer
迎战无声杀手
Sanjeet Bagcchi
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p987
Articles（论著）
21
Global burden of enteric infectious diseases, diarrhoeal diseases, and corresponding aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
1990–2023年肠道传染病与腹泻病全球疾病负担及其病原学特征：2023全球疾病负担研究系统分析
GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p988
22
Efficacy and safety of a 4-month quabodepistat, delamanid, and bedaquiline regimen for drug-susceptible pulmonary tuberculosis: a multicentre, open-label, randomised, proof-of-concept, non-inferiority, phase 2b/c trial
奎博德匹司他+德拉马尼+贝达喹啉4个月方案治疗药物敏感性肺结核的有效性与安全性：一项多中心、开放标签、随机、概念验证、非劣效2b/c期临床试验
Rodney Dawson,Andreas H Diacon,Ebrahim Variava,Tumelo Moloantoa,William Brumskine,Tlhago Ngwanto,Ntokozo Zuma-Gwala,Ayman Osman,Mohammed Rassool,Jaclyn Ann Bennet,Yongge Liu,Raymond Xu,Wei Li,Simbarashe Takuva,Jeffrey Hafkin
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1010
23
Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia
口腔护理预防非机械通气医院获得性肺炎的效果（HAPPEN研究）：澳大利亚一项多中心阶梯整群随机试验
Nicole M White,Philip L Russo,Georgia Matterson,Katrina Browne,Allen C Cheng,Martin Kiernan,Peta E Tehan,Andrew J Stewardson,Nicholas Graves,Auxillia Madhuvu,Helen Rawson,Jenny Sim,Sonja Dawson,Julee McDonagh,Caroline Marshall,Elizabeth Orr,Douglas Johnson,Irani Thevarajan,Pakhi Sharma,Rhonda Wilson,Brett G Mitchell
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1022
24
Effect of a community-based behavioural intervention bundle to improve antibiotic use and patient management in Burkina Faso and DR Congo (CABU-EICO): a cluster-randomised controlled trial
布基纳法索与刚果民主共和国基于社区的综合行为干预措施优化抗生素使用与患者管理的效果（CABU-EICO研究）：一项整群随机对照试验
Brecht Ingelbeen,Daniel Valia,Bijou Mbangi,Esther van Kleef,Linda Campbell,Juste Stéphane Kouanda,César-Augustin Mambuku Khoso Muaka,Eric Wendpouiré Tiendrébeogo,Aminata Welgo,Veerle Bertels,Steven Declercq,Bram Riems,Marie Meudec,Edwin Wouters,Ben S Cooper,Delphin Mavinga Phanzu,Halidou Tinto,Marianne A B van der Sandeon behalf of the CABU-EICO Study Group
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1031
25
Safety and immunogenicity of mRNA-based mpox vaccine candidate BNT166a: an open-label, dose-escalation, first-in-human trial
mRNA候选猴痘疫苗BNT166a的安全性与免疫原性：一项开放标签、剂量递增Ⅰ期人体临床试验
Frank Bähner,Saul N Faust,Leela R L Davies,Olga Blokhina,Donald M Brandon,William B Smith,Vengalil Krishna K Chatterjee,Hana Hassanin,Tara M Babu,Adam Zuiani,Susanne Steinhauser,Asaf Poran,Claire Brittain,Eric Mucker,Jay W Hooper,Robbert G van der Most,Pedro L Alonso,Özlem Türeci,Federico J Mensa,Uğur Şahin
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1045
26
Neutralising antibody responses to MPXV clades Ia, Ib, and IIb after infection or vaccination: a multicountry observational study
感染或接种疫苗后针对猴痘病毒Ia、Ib、IIb分支的中和抗体应答：一项多国观察性研究
Jameson Crandell,Raianna F Fantin,Leonardo Pereira de Araújo,Lauren Lawres,Lauren Pischel,Valter S Monteiro,Luciana Conde,Angelica C Kottkamp,Marie I Samanovic,Rita Cordeiro,Diana Póvoas,Mariana Melo,Terezinha M Castineiras,Andre M Vale,Inci Yildirim,Mark J Mulligan,Leonardo Augusto de Almeida,Saad B Omer,Camila H Coelho,Carolina Lucas
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1058
27
Yellow fever vaccination in healthy Gambian children of different ages to establish safety and immunogenicity of a booster dose: a open-label, non-randomised, single-site, phase 3 vaccine trial
冈比亚不同年龄健康儿童接种黄热病加强针的安全性与免疫原性：一项开放标签、非随机、单中心Ⅲ期疫苗临床试验
Caitlin Pley,David J Jeffries,Ebrima Kanteh,Julia Strandmark,Aru Kumba Baldeh,Mam Nabou Leigh,Peter Ndow,Ed Clarke,Beate Kampmann
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1070
28
Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons
托珠单抗用于重症汉坦病毒肺综合征治疗：MEURI病例系列及对照分析
Fernando Tortosa,Germán Santamaría,Rodrigo Bustamante,Martín Alberto Ragusa,Ayelén Iglesias,Yesica Espasandin,Ariel Izcovich
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：p1079
Review（综述）
29
Expert consensus on case definitions in human loiasis: a Delphi study
人罗阿丝虫病病例定义专家共识：德尔菲法研究
Luzia Veletzky,Spinello Antinori,Sabine Bélard,Marielle Bouyou,Emmanuel Bottieau,Jérémy T Campillo,Cédric B Chesnais,Fernando de la Calle-Prieto,Federico Gobbi,Marc P Hübner,Amy D Klion,Pia Michelitsch,Andreas Neumayr,Tamara Nordmann,Thomas B Nutman,Fernando Salvador,Stephen D Vaughan,Michael Ramharter,Francesca Tamarozzi
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e397
30
A systematic review of Nipah virus disease epidemiological parameters, outbreaks, and mathematical models
尼帕病毒病流行病学参数、疫情暴发及数学模型系统综述
Tristan Naidoo,Christian Morgenstern,Patrick Doohan,Rhys Earl,Thomas Rawson,Richard J Sheppard,Joseph T Hicks,Sreejith Radhakrishnan,Rob Johnson,Anna-Maria Hartner,Lorenzo Cattarino,Kelly McCain,Anna Vicco,Natsuko Imai-Eaton,Sabine van Elsland,Anne Cori,Ruth McCabe,Sangeeta Bhatiathe Pathogen Epidemiology Review Group
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e409
Personal View（个人观点）
31
Understanding and exploiting superspreading to disrupt Mycobacterium tuberculosis transmission
认识并利用超级传播现象阻断结核分枝杆菌传播
Tyler S Brown,Kristin Nelson,Stephen Kissler,Leo Martinez,C Robert Horsburgh,Laura F White,Barun Mathema,Karen R Jacobson
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e423
Grand Round（大查房）
32
Calciphylaxis complicated by NDM-1-producing Pseudomonas aeruginosa: first experience with cefepime–zidebactam alongside phage therapy in the USA
钙性尿毒症性小动脉病合并产NDM-1铜绿假单胞菌感染：美国头孢吡肟-齐德巴坦联合噬菌体治疗首次应用经验
Erlinda R Ulloa,Daniel Jaffurs,M Tuan Tran,Carol Lin,Hung Tran,Dorian Chan,Ali Nael,Sagar U Nigwekar,Mikeljon P Nikolich,Daria Van Tyne
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e433
Clinical Picture（临床图鉴）
33
Lymphoma-like endoscopic appearance of lymphogranuloma venereum
性病性淋巴肉芽肿内镜下淋巴瘤样表现
Takumi Wada,Mariko Kobayashi,Kiichiro Tsuchiya
The Lancet Infectious Diseases. Oct 2026，Vol 26(10)：e444
2026-10-23
Journal of Infection.Volume 93 Issue 1
感染杂志 93卷 1期
https://www.sciencedirect.com/journal/journal-of-infection/vol/93/issue/1
Reviews（综述）
1
Nosocomial outbreaks with rare yeasts: Trends, characteristics and preventive measures
罕见酵母菌引起的院内感染暴发：趋势、特征及预防措施
Bram Spruijtenburg, Aleksandra Marek, Jacques F. Meis, Anuradha Chowdhary, ... Eelco F.J. Meijer
Article 106765
Original Articles（论著）
Infectious Disease Practice（传染病实践）
2
Long-term immunogenicity and safety of RZV primary vaccination and revaccination in kidney transplant recipients
带状疱疹疫苗（RZV）初免及加强免疫在肾移植受者中的长期免疫原性与安全性
Melinda M. Hutton, Peter E. Vink, Adrienne Kuxhausen, Manyee Tsang, ... Yingjun Zhou
Article 106758
3
Health inequalities in Escherichia coli bacteraemia and associated antibiotic resistance: A national surveillance study, England, 2018/19 to 2023/24
大肠埃希菌菌血症中的健康不平等及相关抗生素耐药性：英格兰全国监测研究，2018/19至2023/24
Dimple Y. Chudasama, Olisaeloka Nsonwu, Timothy M. Pollington, Zahin Amin-Chowdhury, ... Russell Hope
Article 106761
4
Determinants offatalities and secondary transmission in laboratory pathogen incidents, 1900–2025
1900–2025年实验室病原体事件中致死因素与二次传播的决定因素
Sandhya Dhawan, Poh Lian Lim, Wirichada Pan-ngum, C. Raina MacIntyre, Stuart D. Blacksell
Article 106766
5
Global disability-adjusted life years burden of lower respiratory infections caused by Streptococcus pneumoniae, Staphylococcus aureus, and Klebsiella pneumoniae, 1990–2021: A systematic analysis of the global burden of disease study 2021
全球肺炎链球菌、金黄色葡萄球菌和肺炎克雷伯菌所致下呼吸道感染的伤残调整生命年负担（1990–2021）：2021年全球疾病负担研究的系统分析
1.Longzhen Lu, Zhiwei Long, Fengzhen Chen, Zhengtu Li, ... Yan Wang
Article 106768
7
Diagnostic value and clinical performance of targeted next-generation sequencing for lower respiratory tract infections: A real-world prospective study
靶向二代测序对下呼吸道感染的诊断价值与临床表现：一项现实世界前瞻性研究
Jinru Gong, Yaowei He, Xiaoxuan Chen, Qiang Lei, ... Jiasheng Yang
Article 106785
Bacteria and Bacterial Diseases（细菌与细菌性疾病）
8
The cause, treatment and outcome of hyponatraemia associated with tuberculous meningitis: An observational study nested within two clinical trials of corticosteroids
结核性脑膜炎相关低钠血症的病因、治疗及转归：基于两项皮质类固醇临床试验的嵌套观察研究
Joseph Donovan, Nguyen Truc Thanh, Lam Hong Bao Ngoc, Nguyen Ho Hong Hanh, ... Guy E. Thwaites
Article 106763
9
Emerging human pathogen: Identifying Spiroplasma ixodetis as a frequent cause of unlocalised febrile illness
新兴人类病原体：鉴定螺旋原体（Spiroplasma ixodetis）为不明原因发热的常见病因
Miša Korva, Petra Bogovič, Nataša Knap, Rok Kogoj, ... Miroslav Petrovec
Article 106776
10
Exposure to antibiotics with anaerobe coverage in later life is associated with higher enteric pathobiont carriage
晚年接触抗菌谱包含厌氧菌的抗生素与肠道共生菌携带率升高有关
Egi Vasil, Lito E. Papanicolas, Sophie J. Miller, Andrew P. Shoubridge, ... Geraint B. Rogers
Article 106774
11
Proteomic biomarkers differentiate bacterial infections in febrile infants: A multicentre prospective study
蛋白质组学生物标志物区分发热婴儿细菌性感染：一项多中心前瞻性研究
Clare Mills, Holly Drummond, Narainrit Karuna, Hannah Mitchell, ... Thomas Waterfield
Article 106782
Viruses and Viral Diseases（病毒与病毒性疾病）
12
Risk of severe influenza in people with a history of injection drug use in Ontario: A population-based nested case control study
安大略省有注射吸毒史人群的重症流感风险：一项基于人群的嵌套病例对照研究
Chloe S. Smith, Zuhal Mohmand, Adriyan Hrycyshyn, Maya Djerboua, ... Anthony D. Bai
Article 106764
13
All-cause mortality within seven days of COVID-19 vaccination: A matched cohort and self-controlled case series study in Lombardy, Italy
COVID-19疫苗接种后七天内全因死亡率：意大利伦巴第地区的匹配队列研究与自身对照病例系列研究
G. Corrao, E. Sguazzini, A. Gori, E. Monti, ... M. Franchi
Article 106769
14
Symptomatology of SARS-CoV-2 versus seasonal coronavirus infection in healthy young children
健康幼儿中SARS-CoV-2与季节性冠状病毒感染的症状学比较
L. Junquera Guinovart, S.E.M. Hauser-van Westrhenen, R. Schuurman, P.C.J.L. Bruijning-Verhagen
Article 106762
15
Prevalence and genotype distribution of cervical human papillomaviruses infection across cytology: A nationwide, cross-sectional study of over 1 million Chinese women from 2020 to 2024
不同细胞学结果中宫颈人乳头瘤病毒感染的患病率及基因型分布：2020–2024年超百万中国女性的全国性横断面研究
Di Gao, Xueyin Wang, Juan Juan, Hui Bi, ... Xiaosong Zhang
Article 106773
16
Real-world effectiveness of influenza vaccination amongst children aged under 5 in a tropical setting
现实中热带地区5岁以下儿童流感疫苗接种的有效性
Liang En Wee, Reen Wan Li Ho, Jue Tao Lim, Soon Kok Lim, ... Kelvin Bryan Tan
Article 106771
Fungi and Fungal Diseases（真菌与真菌性疾病）
17
Prevalence and clinical implications of Aspergillus infection among tuberculosis patients in Peru
秘鲁结核病患者中曲霉感染的患病率及临床意义
Alicia E. Madden, Chuan-Chin Huang, Roger I. Calderon, Leonid Lecca, ... Megan B. Murray
Article 106767
Letters to the Editor（致编辑的信）
18
Potential of neutrophil-to-lymphocyte ratio for severity assessment of pediatric Streptococcus pneumoniae infection: A 10-year analysis
中性粒细胞与淋巴细胞比值在儿童肺炎链球菌感染严重程度评估中的潜力：一项十年分析
Hai-Feng Liu, Ying Yang, Na Zang, En-Mei Liu
Article 106772
19
Pertactin expression in Chinese Bordetella pertussis: A critical reappraisal of PRN inclusion in pertussis vaccines
中国百日咳鲍特菌的丝状血凝素表达：对百日咳疫苗中PRN组分的批判性再评估
Xinyu Wang, Leran He, Yue Li, Qinghong Meng, Kaihu Yao
Article 106777
20
From guidelines to bedside: Oral amoxicillin dosing for Enterococcus faecalis bone and joint infections remains highly variable in clinical practice
从指南到床旁：治疗骨、关节肠球菌感染的阿莫西林口服剂量在临床实践中仍存在明显差异
Bérénice Souhail, Étienne Canouï, Pauline Richebé, Antoine Hamon, ... Raphaël Lepeule
Article 106775
21
Pre-zoonotic adaptation of Andes virus before spillover: Implications for cross-host and human transmission
安德斯病毒溢出前的预人畜共患适应：对跨宿主及人际传播的启示
Junxiang Zhao, Jiayi Wang, Leiliang Zhang
Article 106780
Journal of Infection.Volume 93 Issue 2
感染杂志 93卷 2期
https://www.sciencedirect.com/journal/journal-of-infection/vol/93/issue/2
Reviews（综述）
1.
Global epidemiology and pathogen spectrum of enterovirus-associated encephalitis and meningitis outbreaks from 1960 to 2025: A systematic review and meta-analysis
1960年至2025年肠道病毒相关脑炎和脑膜炎暴发的全球流行病学及病原谱：一项系统综述和荟萃分析
Xinru Zeng, Hong Ji, Jing Wang, Huan Fan, ... Changjun Bao
Article 106781
2.
Evidence for a relationship between concentrations of nucleos/tide analogue agents and treatment outcome in chronic hepatitis B infection: A systematic review
慢性乙型肝炎感染中核苷（酸）类似物药物浓度与治疗疗效相关性证据：系统综述
Gloria Sukali, Motswedi Anderson, Khadija Said Mohammed, Patti Biggs, ... Philippa C. Matthews
Article 106806
Original Articles（论著）
Infectious Disease Practice（传染病实践）
3.
An antibiotic chatbot: Evaluation of a retrieval-augmented generation approach for providing guideline-based antimicrobial advice
抗生素聊天机器人：检索增强生成方法的评估，旨在提供基于指南的抗菌建议
David W. Eyre, Ruth Corrigan, Lauren Hookham, Sheila Lumley, ... Nicola Jones
Article 106789
4.
Immunogenicity and safety of co-administration of a recombinant shingles vaccine with an mRNA COVID-19 or adjuvanted influenza vaccine: a randomised controlled trial
重组带状疱疹疫苗与mRNA COVID-19疫苗或佐剂流感疫苗联合接种的免疫原性和安全性：一项随机对照试验
Rosie Harris, Russell Thirard, Claire McBrien, Alexander Middleditch, ... Isabelle Guiton
Article 106784
5.
Incidence, risk factors and management of paradoxical reaction in central nervous system tuberculosis in the United Kingdom
英国中枢神经系统结核异常反应的发生率、危险因素及治疗
Emma C. Carter, Cristina Fernandez, Charlotte Lim, Tehmina Bharucha, ... Fiona McGill
Article 106778
6.
Clinical epidemiological characteristics of hospitalized pediatric Mycoplasma pneumoniae pneumonia in China
中国住院儿童支原体肺炎的临床流行病学特征
Xinyu Wang, Ju Yin, Baoping Xu, Guanhua Xue, ... Liwei Gao
Article 106793
7.
Factors associated with severe health outcomes among community-dwelling older adults hospitalized with respiratory syncytial virus
社区居住老年人群中呼吸道合胞病毒住院后严重健康结局的相关因素
Vajini N. Atukorale, Jeffrey C. Kwong, Alejandro Hernandez, Rahim Moineddin, ... Sarah A. Buchan
Article 106797
8.
A randomised comparison of management strategies for drug-induced liver injury associated with tuberculous meningitis treatment
结核性脑膜炎治疗相关药物性肝损伤管理策略的随机对照比较
Joseph Donovan, Tran Thai Hung, Nguyen Thi Thu Hiep, Ho Dang Trung Nghia, ... Guy E. Thwaites
Article 106796
9.
Convergent neutralizing antibodies to SARS-CoV-2 variants over 2.5 years after BA.5/BF.7 breakthrough infection
BA.5/BF.7 暴发感染后 2.5 年内针对 SARS-CoV-2 变异株的趋同中和抗体
Meng Kong, Hui-Xia Gao, Xue-Dong Song, Guo-Jian Yang, ... Mai-Juan Ma
Article 106799
10.
Respiratory viral detection in adult severe acute respiratory infection post-COVID-19 pandemic: implications for antimicrobial stewardship
新冠疫情后成人重症急性呼吸道感染呼吸道病毒检测：对抗菌药物管理工作的启示
Elen Vink, Michael.E. Murphy, Rory Gunson, Alisdair MacConnachie, ... Antonia Ho
Article 106805
11.
Systemic inflammatory networks in HIV-associated chronic obstructive pulmonary disease
人类免疫缺陷病毒相关慢性阻塞性肺疾病的全身炎症网络
Lennart Riemann, Lena Böger, Carina Dahl, Timo Gemoll, ... Christine Happle
Article 106814
12.
Sepsis, atrial fibrillation and mortality risk: an updated systematic review and meta-analysis of >3 million patients
败血症、房颤与死亡风险：一项基于300多万患者的最新系统综述与荟萃分析
Vito Maria Daniele Cormaci, Danilo Menichelli, Daniele Malatesta, Francesco Del Sole, ... Daniele Pastori
Article 106818
Bacteria and Bacterial Diseases（细菌及细菌性疾病）
13.
Prevalence of key bacterial pathogens among children with pharyngotonsillitis in The Gambia – a case-control study
冈比亚儿童咽扁桃体炎中关键细菌病原体的流行率——一项病例对照研究
David Nygren, Sheikh Jarju, Mary Basiru Njai, Sukai Jagne, ... Edwin Armitage
Article 106787
14.
Multi-strain Clostridioides difficile infection: Increased detection and clinical implications
多菌株艰难梭菌感染：检出率增加及其临床意义
Mônica J. Rodrigues-Jesus, Maria L.G.S. Morais, Jae Hyun Shin, Guruprasad V. Konduru, ... Cirle A. Warren
Article 106800
15.
Streptococcus agalactiae bone and joint infection: a multicentre observational study 2014-23
无乳链球菌骨关节感染：2014—2023 年一项多中心观察性研究
Simon Jamard, Mathilde Jan, Gwenael Le moal, Chloe Plouzeau-jayle, ... Adrien Lemaignen
Article 106804
16.
Metagenomic sequencing as a diagnostic tool for urine culture negative febrile urinary tract infection
宏基因组测序作为尿培养阴性发热性尿路感染的诊断工具
V.A. Janes, J.E. Stalenhoef, B.C.L. van der Putten, L.A.M. Koster, ... D.R. Mende
Article 106783
17.
Within-host evolution of tandemly duplicated blaKPC-14 conferring cross-resistance to ceftazidime-avibactam, cefiderocol and aztreonam-avibactam in hypervirulent ST11 Klebsiella pneumoniae
高毒力ST11型肺炎克雷伯菌体内串联重复blaKPC-14基因在宿主体内进化研究——该基因介导对头孢他啶-阿维巴坦、头孢地尔及氨曲南-阿维巴坦交叉耐药
Fuyao Hu, Yi Zhang, Mingju Hao, Wei Li
Article 106810
18.
National and subnational burden of HIV-negative MDR-TB in China, 1990–2023: Spatio-temporal heterogeneity, long-term trends, and projections
1990-2023年中国国家及以下层面HIV阴性耐多药结核病负担：时空异质性、长期趋势及预测
Shunxian Zhang, Jinlei Qi, Jinxin Zheng, Yu Qin, ... Hui Jiang
Article 106816
Viruses and Viral Diseases（病毒及病毒性疾病）
19.
Maternal HIV viral load threshold for guiding extended infant prophylaxis
用于指导延长婴儿预防用药的母体HIV病毒载量阈值
Jean-Pierre Molès, Morgana D’Ottavi, David Rutagwera, Dramane Kania, ... Connie Osborne
Article 106779
20.
Burden and economic impact of RSV hospitalisations among English adults, 2023/24
2023/24年度英国成年人因呼吸道合胞病毒（RSV）住院的负担和经济影响
Tiffany Truong, Jennifer M. Radin, Lillian Li, José M. Ordóñez-mena, ... Joan E. Madia
Article 106792
21.
Impact of EV-A71 vaccination and non-pharmaceutical interventions on hand, foot, and mouth disease: A 14-year interrupted time series analysis
EV-A71疫苗接种与非药物干预措施对手足口病的影响：一项14年的中断时间序列分析
Shuaibing Dong, Mengyao Li, Da Huo, Hao Zhao, ... Peng Yang
Article 106795
22.
Age-associated impairment of humoral and cellular immune responses to SARS-CoV-2 in a large community cohort with hybrid immunity
合并混合免疫的大型社区队列中，SARS-CoV-2体液和细胞免疫反应的年龄相关性降低
Jinqiu Ran, Liguo Zhu, Mingzhe Ning, Wanying Zhang, ... Yuxin Chen
Article 106803
23.
Genomic characterization of a large-scale chikungunya outbreak in China
中国一次大规模基孔肯雅热疫情的基因组特征分析
Lirong Cao, Dongfeng Kong, Jingzhi Lou, Xiran Wang, ... Ziquan Lv
Article 106801
24.
Hospitalizations and deaths from major respiratory viruses in the US: An ensemble time series modeling study, 2016–2025
2016—2025年美国主要呼吸道病毒相关住院与死亡病例研究：集成时间序列模型分析
Chelsea L. Hansen, Nabila Shaikh, Sarah Naeger, Laurence Torcel-Pagnon, ... Cecile Viboud
Article 106811
Fungi and Fungal Diseases（真菌及真菌性疾病）
25.
Pneumocystis jirovecii pneumonia in solid organ transplant recipients: a prospective observational cohort study
实体器官移植受者肺孢子菌肺炎：一项前瞻性观察性队列研究
Alexandre Alanio, Karine Boukris-Sitbon, Thomas Obadia, Marie Desnos-Ollivier, ... Olivier Lortholary
Article 106794
26.
Defining the threshold duration of candidemia associated with poor outcomes: Redefining persistent candidemia
定义与不良预后相关的念珠菌血症持续时间阈值：重新定义持续性念珠菌血症
Marta Albanell-Fernández, Andrea Vergara, Celia Cardozo, Sabina Herrera, ... Álex Soriano
Article 106798
Parasites and Parasitic Diseases（寄生虫与寄生虫病）
27.
Landscape and ecological correlates of tick-associated viruses in Inner Mongolia, China
中国内蒙古蜱传病毒的分布格局及其生态关联因素研究
Chunfu Li, Jian Li, Rui Ma, Yanli Zhang, ... Xinyu Feng
Article 106802
Letters to the Editor（致编辑的信）
28.
Remdesivir triphosphate as a potential repurposed drug against the emerging Bundibugyo Ebolavirus 2026
瑞德西韦三磷酸作为针对2026年新兴本迪布焦埃博拉病毒的潜在老药新用
Mansi Dutt, Misaki Wayengera, Gustavo Sganzerla Martinez, Anuj Kumar, ... Wilber Sabiiti
Article 106788
29.
Scarlet fever resurgence and declining mortality in China: Rethinking diagnosis and surveillance
中国猩红热再现与死亡率下降：重新审视诊断与监测
Mengyang Guo, Wei Shi, Siyu Chen, Qinghong Meng, Kaihu Yao
Article 106791
30.
Emergence of New Delhi metallo β-lactamase-5 in carbapenem-resistant Salmonella from six pediatric cases in Guangxi, China
中国广西6例儿童感染耐碳青霉烯沙门菌中出现新德里金属β-内酰胺酶-5
Jiale Chen, Bei Wei,, Yinxiu Mo, Ziru Yang, ... Xuebin Xu
Article 106786
31.
Identification of an early-formed HIV-1 circulating recombinant form (CRF202_BC) in the southern border region of Yunnan, China
中国云南边境南部地区一株早期形成的HIV-1循环重组型毒株（CRF202_BC）鉴定
Min Chen, Huichao Chen
Article 106808
32.
Home-based rapid testing and early antiviral treatment as a potential strategy to blunt pediatric influenza peak
居家快速检测联合早期抗病毒治疗作为抑制儿童流感发病高峰的潜在防控策略
Youran Li, Ting Zhang, Jie Gao
Article 106807
33.
High prevalence and global distribution of carbapenem resistance genes in Enterobacter hormaechei strains
霍氏肠杆菌菌株中碳青霉烯类耐药基因的高流行率与全球分布特征
Yanan Wang, Xuebin Xu
Article 106812
34.
Global surveillance reveals progressive erosion of benzylpenicillin susceptibility in Streptococcus suis
全球监测显示，猪链球菌对青霉素的敏感性逐渐降低
Ting-Yin Lu, Shao-Jie Wu, Xi-Bo-Ni, Yue-Yuan Peng, ... Yu-Feng Zhou
Article 106790
Corrigenda/Errata（勘误表）
35.
Corrigendum to “Genomic epidemiology and antimicrobial resistance reveal local transmission dynamics of enteric fever in Shenzhen, one of the mega cities in China” [J Infect, Volume 90, Issue 4 (2025) Page 3/106469]
勘误：“基因组流行病学和抗菌药物耐药性揭示了中国特大城市之一深圳的肠道热病本地传播动态” [J Infect, 第90卷, 第4期 (2025) 第3页/106469]
Yixiang Jiang, Min Jiang, Xin Lu, Meiying Yan, ... Biao Kan
Article 106809
Journal of Infection.Volume 93 Issue 3
感染杂志 93卷 3期
https://www.sciencedirect.com/journal/journal-of-infection/vol/93/issue/3
Reviews（综述）
1.
Cefiderocol in clinical practice: From randomised trials to real-world evidence in the management of multidrug-resistant Gram-negative bacterial infections
头孢地尔临床应用：多重耐药革兰阴性菌感染诊疗 —— 从随机对照试验到真实世界证据
Francesca Di Bartolomeo, Matteo Augello, Giulia Marchetti
Article 106821
2.
Pre-existing and cross-reactive immunity to avian influenza H5N1 in humans: Implications for pandemic risk and vaccine strategies
人群中针对 H5N1 禽流感的预存免疫与交叉反应性免疫：对大流行风险及疫苗策略的启示
Iván Sanz-Muñoz, Carlos J. Ciria-Gil, Marta Hernandez, Cesar Santiago, ... Aitor Nogales
Article 106822
3.
Core biomarkers and early detection criteria of cytokine storm triggered by infectious diseases: A systematic review and meta analysis
感染性疾病诱发细胞因子风暴的核心生物标志物与早期识别标准：一项系统综述与荟萃分析
Junyu Yin, Xianxu Huang, Xin Ou, Shilin Xu, ... Qingkun Song
Article 106826
4.
Microbe-induced migrasome-like structures and their role in microbial persistence, immune evasion and transmission
微生物诱导的迁移小体样结构及其在微生物持留、免疫逃逸与传播中的作用
Mingyan Feng, Leiliang Zhang
Article 106832
Original Articles（论著）
Infectious Disease Practice（传染病实践）
5.
Impact of dosing interval on immunogenicity following a heterologous typhoid conjugate vaccine booster in Nepalese children: An observational study
尼泊尔儿童异源伤寒结合疫苗加强针接种间隔对免疫原性的影响：一项观察性研究
Yiyuan Zhang, Sonu Shrestha, Francesca Feaheny, Dikshya Pant, ... Xinxue Liu
Article 106823
6.
Mycobacterium tuberculosis pathogen load and associated inflammatory responses define infection severity in HIV-associated TB and interact with age to predict mortality
结核分枝杆菌病原体载量及相关炎症反应可判定 HIV 合并结核病的感染严重程度，并与年龄交互作用以预测患者死亡风险
Linda Boloko, Charlotte Schutz, Amy Ward, Robert J. Wilkinson, ... David A. Barr
Article 106828
7.
Spatial patterns of rodent-borne pathogens and ecological suitability of rodent-borne diseases in China
中国鼠传病原体的空间格局与鼠传疾病的生态适宜性
Hongyan Wu, Kang Yu, Yurun Xue, Meng Lu, ... Shuo Su
Article 106824
8.
Household transmission dynamics of human respiratory syncytial virus in China: A multicentre epidemiological and molecular study
中国人类呼吸道合胞病毒的家庭传播动力学：一项多中心流行病学与分子学研究
Qiuyao Duan, Xinwen Jin, Xiaofei Fu, An Zhu, ... Shelan Liu
Article 106834
9.
Target enriched metagenomics in cerebrospinal fluid in central nervous system infections
中枢神经系统感染中脑脊液的靶向富集宏基因组学研究
Sabine E. Olie, Steven L. Staal, Ana C. da Cruz Campos, Diederik van de Beek, Matthijs C. Brouwer
Article 106841
Bacteria and Bacterial Diseases（细菌及细菌性疾病）
10.
Clinical characteristics, outcomes and molecular epidemiology of group B streptococcal disease in young infants in the Netherlands
荷兰低龄婴儿 B 族链球菌感染的临床特征、预后及分子流行病学研究
Marleen A. Groenveld, Douwe H. Visser, Matthijs C. Brouwer, Dorota Jamrozy, ... Merijn W. Bijlsma
Article 106815
11.
Genomic characterisation of ST11-KL19 carbapenem-resistant Klebsiella pneumoniae carrying dual carbapenemases and hypervirulence-associated markers
携带双碳青霉烯酶及高毒力相关标志物的 ST11-KL19 型耐碳青霉烯肺炎克雷伯菌基因组特征分析
Zelin Yan, Yuchen Wu, Jing Wang, Haojin Dong, ... Rong Zhang
Article 106813
12.
Neonatal sepsis and meningitis caused by Group B Streptococcus or Escherichia coli in twins. A systematic review
双胎新生儿 B 族链球菌或大肠埃希菌所致败血症与脑膜炎：一项系统综述
Marleen A. Groenveld, Francesca Miselli, Roberta Creti, Martina Buttera, ... Merijn W. Bijlsma
Article 106817
13.
Oropharyngeal microbiome signatures associated with meningococcal carriage in healthy young adults
健康青年人群中与脑膜炎奈瑟菌携带相关的口咽部微生物组特征
Diana Roif-Kaminsky, Daniel Grupel, Noa Sofer-Sali, Yair Motro, Jacob Moran-Gilad
Article 106830
14.
A prospective cohort study of the clinical profile of Acinetobacter baumannii and Acinetobacter nosocomialis infections in Thailand
泰国鲍曼不动杆菌与医院不动杆菌感染的临床特征前瞻性队列研究
Saranta Freeouf, Samantha Palethorpe, Cassandra Fairhead, Chidchamai Kewcharoenwong, ... Jeremy S Brown
Article 106842
Viruses and Viral Diseases（病毒及病毒性疾病）
15.
Serological outcomes of SARS-CoV-2 infection by vaccination status and variant in England
英格兰地区依据疫苗接种状态与病毒变异株分层的严重急性呼吸道综合征新冠病毒2型感染血清学转归研究
Catherine Quinot, Rachel Lunt, Freja Kirsebom, Nick Andrews, ... Jamie Lopez Bernal
Article 106819
16.
Effectiveness and waning of the fourth dose mRNA COVID-19 vaccines for the prevention of SARS-CoV2 infection related hospitalisations and deaths
第四剂 mRNA 新冠疫苗预防 SARS‑CoV‑2 感染相关住院与死亡的保护效力及其衰减情况
Xintong Li, Núria Mercadé-Besora, Amy Shuk-Man Lam, Cesar Barboza, ... Annika M. Jödicke
Article 106825
17.
Genetic analysis of human adenovirus type 7 circulating in China during 2014-2025
2014‑2025 年我国流行的 7 型人腺病毒的基因分析
Jinjin Wang, Ling Jing, Yali Duan, Xiaolei Guan, ... Zhengde Xie
Article 106829
18.
Cross-neutralizing antibody responses to diverse coronaviruses in the human population
人群对多种冠状病毒的交叉中和抗体应答
Shixiong Zhou, Chunhai Liu, Weiyong Liu, Kun Cai, ... Lihong Liu
Article 106827
19.
Dose-dependent efficacy of intravenous brincidofovir across adenovirus species in immunocompromised patients
静脉注射布林西多福韦对免疫功能低下患者各型腺病毒的剂量依赖性疗效
Chantal Lucini, Nkechie Azie, Sunando Roy, Helena Tutill, ... Thomas Lion
Article 106835
Parasites and Parasitic Diseases（寄生虫与寄生虫病）
20.
Association of asymptomatic Plasmodium falciparum infections and its treatment with short-term cognitive performance in school-aged children: A prospective cohort study in western Kenya
肯尼亚西部学龄儿童无症状恶性疟原虫感染及其治疗与短期认知能力的关联：一项前瞻性队列研究
Megan S. McHenry, George Ayodo, Irene Marete, Chloe M. Hasund, ... Tuan M. Tran
Article 106831
Protozoa and Protozoal Diseases（原虫及原虫病）
21.
Potential Targets of Naturally Acquired Plasmodium vivax Transmission - Reducing Antibodies
自然获得的间日疟原虫传播阻断抗体的潜在作用靶点
Rattanaporn Rojrung, Sataporn Thongpoon, Takaaki Yuguchi, Wanlapa Roobsoong, ... Eizo Takashima
Article 106833
Corrigenda/Errata（更正/勘误表）
22.
Corrigendum to “Global disability-adjusted life years burden of lower respiratory infections caused by Streptococcus pneumoniae, Staphylococcus aureus, and Klebsiella pneumoniae, 1990–2021: A systematic analysis of the global burden of disease study 2021″ [J Infect 93 (2026) 106768]
《1990‑2021年肺炎链球菌、金黄色葡萄球菌及肺炎克雷伯菌所致下呼吸道感染的全球伤残调整生命年负担：2021年全球疾病负担研究的系统分析》勘误［J Infect，2026，93：106768］
Longzhen Lu, Zhiwei Long, Fengzhen Chen, Zhengtu Li, ... Yan Wang
Article 106837
Journal of Infection.Volume 93 Issue 4
感染杂志 93卷 4期
https://www.sciencedirect.com/journal/journal-of-infection/vol/93/issue/4
Reviews（综述）
1.
Cardiovascular outcomes and acute human metapneumovirus infection in adults: A systematic literature review
成人急性人偏肺病毒感染与心血管预后：系统文献综述
Paul Loubet, François Roubille, Odile Launay, Slim Fourati, ... Oliver Martyn
Article 106843
2.
Risk stratification for tuberculosis reactivation in patients receiving biological and non-biological immunomodulators: A review of current literature
接受生物制剂与非生物免疫调节剂治疗患者的结核复燃风险分层：现有文献综述
Qiaoling Ruan, Qingluan Yang, Ci Chu, Feiran Zhou, ... Wenhong Zhang
Article 106840
3.
Global epidemiology, clinical burden, and antimicrobial resistance of the WHO priority pathogens: An updated review focusing on understudied non-baumannii Acinetobacter and emerging extensively drug-resistant threats
世界卫生组织重点病原体的全球流行病学、临床疾病负担与耐药情况：聚焦研究不足的非鲍曼不动杆菌及新发广泛耐药威胁的最新综述
Shulei Jia, Xiang Zhang, Lingling Chen, Wanying Gao, ... Guiliang Zheng
Article 106858
4.
Epidemiology of invasive fungal infection in acute leukaemia to inform infection prevention and surveillance practice: A systematic review and meta-analyses
急性白血病侵袭性真菌感染的流行病学特征：为感染防控与监测实践提供依据—— 一项系统综述与 Meta 分析
Priya Garg, Gemma K. Reynolds, Chin Fen Neoh, Tim Spelman, ... Leon J. Worth
Article 106868
Original Articles（论著）
5.
Comparative efficacy and safety of pharmacological regimens for Mycobacterium avium complex pulmonary disease and bacteremia: A systematic review with separate network meta-analyses
鸟分枝杆菌复合群肺病及菌血症药物治疗方案的疗效与安全性比较：一项含独立网状 Meta 分析的系统综述
Qinglin Cheng, Liwen Guo, Ruoqi Dai, Zijian Fang, ... Junfang Chen
Article 106871
6.
From detection to prediction: Asymptomatic shedding-informed mass-balance modeling predicts travel-borne viral importation at airports
从检测到预测：基于无症状排毒信息的质量平衡模型可预测机场输入性旅行相关病毒
Shifu Peng, Yao Deng, Jiayi Liu, Xinyan Du, ... Songzhe Fu
Article 106866
7.
Ecological and host-related drivers of spatial clustering and persistence of human echinococcosis in Xinjiang, China
中国新疆地区人体包虫病空间聚集性与持续流行的生态学及宿主相关驱动因素
Baoping Guo, Gang Guo, Wenqiang Tang, Xiaohan Si, ... Hao Wen
Article 106859
Infectious Disease Practice（传染病实践）
8.
Clinical validation of an optimised metagenomic nanopore sequencing method for detecting viral respiratory pathogens
一种经优化的宏基因组纳米孔测序方法用于呼吸道病毒病原体检测的临床验证
Nicholas D. Sanderson, Kate E. Dingle, Katie M.V. Hopkins, Ali Vaughan, ... Bernadette C. Young
Article 106839
9.
Antenatal pertussis vaccine effectiveness in England remains high post COVID-19
新冠疫情后英格兰地区产前百日咳疫苗保护效力仍维持较高水平
Jemma L. Walker, Sonia Ribeiro, David Litt, Tara Patel, ... Helen Campbell
Article 106836
10.
Hypervirulent serogroup W meningococcal strain belonging to the ST-11 clonal complex is associated with higher case fatality rates: Nationwide cohort study of invasive meningococcal disease caused by serogroup W in England from 2010-2019
属于 ST-11 克隆复合群的高毒力 W 群脑膜炎奈瑟菌菌株与致死率升高相关：2010—2019 年英国 W群侵袭性脑膜炎球菌病全国队列研究
Catherine Isitt, Helen Campbell, Jay Lucidarme, Stephen A. Clark, ... Shamez N. Ladhani
Article 106844
11.
Epidemiology and outcomes of Group A streptococcal and non-Group A streptococcal septic arthritis in French children between 2010 and 2023, a national cohort analysis, and case-control study
2010—2023年法国儿童 A 组链球菌与非 A 组链球菌化脓性关节炎的流行病学特征及临床结局：一项全国队列分析与病例对照研究
Manon Pigeolet, Edouard Haumont, Jade Burnouf-Lim, GAS-Ortho, ... Alina Badina
Article 106847
12.
Explaining variation in antibiotic prescribing for common infections: A three-way variance decomposition using UK primary care data
常见感染抗生素处方差异的成因解析：基于英国基层医疗数据的三方方差分解研究
Nam Nguyen, Julie V. Robotham, A. Sarah Walker, David W. Eyre, ... Koen B. Pouwels
Article 106865
13.
Comparative serious infection and sepsis risks with advanced therapies in IMIDs: A Bayesian network meta-analysis
免疫介导性炎症性疾病中新型疗法相关严重感染与脓毒症风险比较：一项贝叶斯网状 Meta 分析
Victoria Allen, Mark Gibson, Maryam Adas, Rohan Chavali, ... James Galloway
Article 106864
14.
Host immune biomarkers associated with infection risk after CAR T-cell therapy
CAR-T 细胞治疗后与感染风险相关的宿主免疫生物标志物
Gemma K. Reynolds, Lewis Williams, Goknur Giner, Alex Garnham, ... Benjamin W. Teh
Article 106863
Bacteria and Bacterial Diseases（细菌及细菌性疾病）
15.
Early sputum bacterial load dynamics predict treatment response in multidrug-resistant/rifampicin-resistant tuberculosis: A multicenter prospective cohort study
早期痰菌载量动态变化可预测耐多药/利福平耐药肺结核的治疗应答：一项多中心前瞻性队列研究
Fuzhen Zhang, Zilong Yang, Min Jiang, Xiaomeng Hu, ... Yu Pang
Article 106838
16.
Long-term mortality and late sequelae after bacterial meningitis: A matched cohort study with six decades of follow-up
细菌性脑膜炎后的长期死亡风险与远期后遗症：一项随访60年的匹配队列研究
Pelle Trier Petersen, Niels Obel, Lars Haukali Omland, Malte Mose Tetens, ... Christian Thomas Brandt
Article 106846
17.
Dual-species interactions with intestinal bacteria drive multi-drug resistance in Campylobacter
与肠道细菌的双物种互作驱动弯曲菌多重耐药性产生
Sangeeta Banerji, Gudrun Holland, Michael Laue, Antje Flieger
Article 106852
18.
Epidemiological trends, health inequality, and forecasting of Brucellosis in China, 2004-2030
2004—2030年中国布鲁氏菌病的流行病学趋势、健康不平等及预测研究
Hongju Duan, Mingzhe Jiang, Xiaozhe Geng, Xianglin Wu, ... Jian Sun
Article 106854
19.
Clinical and population genomic epidemiology of invasive group A streptococcus in Scotland, 2014-2024
2014—2024年苏格兰侵袭性 A 组链球菌的临床与群体基因组流行病学研究
Stephen B. Beres, Davide Pagnossin, Randall J. Olsen, S. Wesley Long, ... James M. Musser
Article 106860
Viruses and Viral Diseases（病毒与病毒性疾病）
20.
Phase 2 evaluation of two GEO-CM04S1 dose levels shows comparable safety and broad immunogenicity
两种 GEO-CM04S1 剂量水平的 Ⅱ 期评价显示安全性相当，且可产生广泛免疫原性
Sandra Ortega-Francisco, Maria Teresa Prudente de Aquino, Flavia Chiuppesi, Miguel-Angel Gutierrez-Franco, ... Don J. Diamond
Article 106855
21.
Ethnic differences in inactivated influenza vaccine immunogenicity in UK healthcare workers: A two-year prospective longitudinal study
英国医护人员灭活流感疫苗免疫原性的族裔差异：一项为期2年的前瞻性纵向研究
Joshua Nazareth, Christopher A. Martin, Daniel Pan, Ian G. Barr, ... Manish Pareek
Article 106862
Parasites and Parasitic Diseases（寄生虫与寄生虫病）
22.
Protective immunity to clinical malaria is modified by the genetic diversity of P. falciparum antigens
恶性疟原虫抗原的遗传多样性可改变临床疟疾的保护性免疫应答
Myo T. Naung, Ramin Mazhari, Rhea J. Longley, Somya Mehra, ... Alyssa E. Barry
Article 106845
Letters to the Editor（致编辑的信）
23.
Re-emergence of H10N3 avian influenza viruses in China: Evolutionary dynamics and emerging zoonotic risk
H10N3禽流感在中国重现：进化动力学与人畜共患病新发风险
Xiuqi Zhu, Yujie Deng,, Gaojie Xiao, Jiacheng Zhang, ... Jiahao Zhang
Article 106848
24.
Abrupt emergence of 17 blaNDM-5-positive carbapenem-resistant Salmonella Typhimurium ST34 in Wuhan, China, in 2025
2025 年中国武汉突发出现 17 株携带 blaNDM-5 基因的耐碳青霉烯鼠伤寒沙门菌 ST34 型
Lei Xi, Changzhen Li, Hanwang Zhou, Zhen Wang, ... Xiaomei Wang
Article 106849
25.
SARS‑CoV‑2 spike CTD suppresses host metabolism but restricts viral entry through a PDZ‑dependent trade‑off
新冠病毒刺突蛋白 C 端结构域可抑制宿主代谢，并通过依赖 PDZ 结构域的权衡效应限制病毒入侵
Jing Qian, Zhiwen Zhang, Leiliang Zhang
Article 106857
26.
Rezafungin in ocular candidiasis: First paired plasma and aqueous-humour concentrations
瑞扎芬净用于眼部念珠菌病：首组配对的血浆与房水药物浓度研究
Bérénice Souhail, Léo Froelicher Bournaud, Aurélien Dinh, Michelle Saliba, ... Caroline Charlier
Article 106856
27.
First genomic evidence of reassortment in Andes virus
安第斯病毒基因重配的首份基因组学证据
Junxiang Zhao, Leiliang Zhang
Article 106861
28.
Meta-analysis of maternal SARS-CoV-2 infection and child growth and development
母亲SARS-CoV-2感染与儿童生长发育的Meta分析
Xiyun Rao, Hua Fan, Shiyi Ding, Chi Zhang, ... Lijun Zhao
Article 106869
29.
A rapid and simple method for quantifying rezafungin in human plasma
人血浆中瑞扎芬净快速简便定量检测方法
Eyrian Aubin-Beale, Maxime Kolmayer, Allan Kolodziej, Heiko Palma, ... Julien Scala-Bertola
Article 106867
30.
Interaction-dependent tolerance is not multidrug resistance in Campylobacter
弯曲杆菌中相互作用依赖性耐受并非多重耐药
Yifan Ren, Xijuan Jiang
Article 106870
Corrigenda/Errata（勘误）
31.
Corrigendum to “The immunogenicity, reactogenicity, and safety of a bivalent mRNA or protein COVID-19 vaccine given as a fourth dose” [J Infect 90 (2025)/106447]
勘误：《四剂次二价mRNA或蛋白新冠疫苗的免疫原性、反应原性及安全性》[J Infect,2025,90卷:106447]
Nadia Mazarakis, Zheng Quan Toh, Eleanor Neal, Kathryn Bright, ... Paul V. Licciardi
Article 106850
32.
Corrigendum to ‘Immunogenicity and efficacy over 12 months following a fourth dose of a bivalent mRNA or protein-based COVID-19 vaccine: A randomised controlled trial in Australia’ [J Infect92 (2026)/106727]
勘误：《二价mRNA或蛋白新冠疫苗第4剂接种后12个月免疫原性与保护效力：澳大利亚一项随机对照试验》[J Infect,2026,92卷:106727]
Nadia Mazarakis, Zheng Quan Toh, Eleanor Neal, Cattram Nguyen, ... Paul V. Licciardi
Article 106851
33.
Corrigendum to “Immunogenicity and safety of co-administration of a recombinant shingles vaccine with an mRNA COVID-19 or adjuvanted influenza vaccine: A randomised controlled trial” [J Infect 93 (2026) 106784]
《重组带状疱疹疫苗与 mRNA 新冠疫苗或佐剂流感疫苗联合接种的免疫原性与安全性：一项随机对照试验》勘误[J Infect，2026，93 卷：106784]
Rosie Harris, Russell Thirard, Hina Iftikhar, Alexander Middleditch, ... Isabelle Guiton
Article 106853
2026-10-23
International Journal of Antimicrobial Agents Volume 67, Issue 12
国际抗微生物制剂杂志 67卷 12期
https://www.sciencedirect.com/journal/international-journal-of-antimicrobial-agents/vol/67/issue/12
Hot Topic（热点）
1.
The pitfalls of HIV-1 DNA resistance genotyping: What it can and cannot tell us
HIV-1 DNA 耐药基因分型的局限：其所能提供和不能提供的信息
Gilbert Mchantaf, Laurence Morand-Joubert, Antoine Cheret, Laurent Hocqueloux, Véronique Avettand-Fenoel
Article 108026
2.
Antibacterial dose optimisation in patients with febrile neutropenia: Are we targeting the right patients and the right endpoints?
发热伴中性粒细胞减少症患者的抗菌药物剂量优化：我们是否选对了目标人群与研究终点？
João Paulo Telles, Birgit Koch
Article 108024
Klebsiella pneumoniae（肺炎克雷伯菌）
3.
Remodelling the host immune microenvironment in carbapenem-resistant Klebsiella pneumoniae: An evidence-graded framework for host-directed intervention
耐碳青霉烯肺炎克雷伯菌感染中宿主免疫微环境重塑：宿主导向干预的证据分级框架
Xiaolin Liang, Junwei Wang, Chao Liu, Qingyuan Gao, ... Yan He
Article 108000
Reviews（综述）
4.
Pharmacokinetic and pharmacokinetic/pharmacodynamic (PK/PD) considerations of ceftaroline and ceftobiprole for the treatment of Staphylococcus aureus infections: A systematic review
头孢洛林与头孢比罗治疗金黄色葡萄球菌感染的药代动力学及药代/药效学（PK/PD）考量：系统评价
Camilla Genovese, Marta Colaneri, Enrico Sguazzini, Donatella Maddalena, ... Marta Ulldemolins
Article 107959
5.
Antibiotic resistance in Helicobacter pylori: pathogenic mechanisms and eradication barriers
幽门螺杆菌的抗生素耐药性：致病机制与根除障碍
Meenakshi Kandpal, Siddharth Singh, Harshita Shrivastava, Himanshi Jindal, ... Hem Chandra Jha
Article 107981
6.
Clinical pharmacology and therapeutic considerations of isavuconazole in special populations: A narrative review
艾沙康唑在特殊人群中的临床药理学特征与治疗考量：叙述性综述
Shichao Zhu, Rongsong Xia, Jing Yang, Fei Tang, ... Xuewen Qiu
Article 108005
7.
Nipah virus: An exceptionally virulent emerging zoonotic pathogen
尼帕病毒：一种高毒力新发人兽共患病病原体
Hao Sun, Xin Yuan, Jinyan Li, Xitang Li, ... Guangcai Duan
Article 107990
8.
Examining the global antimicrobial resistance surveillance landscape in food-producing animals
食用动物全球抗菌药物耐药性监测体系现状探析
Vika Li, Shaina Craig, Shabbir Simjee
Article 108008
9.
Convergence of carbapenem resistance and hypervirulence in Klebsiella pneumoniae in Europe: A systematic review
欧洲肺炎克雷伯菌中碳青霉烯耐药与高毒力的融合现象：一项系统综述
Axelle Vasseur, Marie Fave, Sarah Ronsin, Thierry Naas, ... Agnès B. Jousset
Article 108028
10.
Advancing bacteriophage therapy through encapsulation: An evidence-based scoping review from animal trials
通过包封技术推进噬菌体疗法：基于动物试验的循证范围综述
Ismail Hossain, Sam Abraham, Jasim M. Uddin
Article 108032
Full Length Articles（全文论著）
11.
Proteomics reveals the mechanism by which sodium oleate decreases Escherichia coli susceptibility to gentamicin
蛋白质组学揭示油酸钠降低大肠埃希菌对庆大霉素敏感性的机制
Lvyuan Fan, Jingyun Wu, Ziyi Zhang, Liting Cai, ... Guozhu Ye
Article 107989
12.
Real-world use of liposomal amphotericin B: A large retrospective, observational, multicentre study
脂质体两性霉素 B 在现实中的应用：一项大型回顾性观察性多中心研究
Claudia Bartalucci, Daniele Roberto Giacobbe, Marco Muccio, Silvia Sisto, ... Giulia Viero
Article 107952
13.
Global burden of bacterial antimicrobial resistance among children under 5 years 1990−2021: A systematic analysis with forecasts to 2050
1990—2021年全球5岁以下儿童细菌耐药性疾病负担：系统分析及至2050年预测
Shanshan Wang, Fei Xie, Shaowei Sang
Article 107995
14.
Evaluation of vancomycin bolus/standard and continuous infusion on nephrotoxicity in a rat model
大鼠模型中万古霉素推注/常规给药与持续输注方案的肾毒性评价
Sylwia Marianski, Gwendolyn M. Pais, Colin Jeantet, Renz Paulo Melicor, ... Marc H. Scheetz
Article 107988
15.
Prevalence of third-generation cephalosporin-resistant Salmonella in animals in China: The key role of ESBL, AmpC, and other β-lactamase strains in the genome
我国动物源第三代头孢菌素耐药沙门菌流行情况：ESBL、AmpC 及其他 β- 内酰胺酶菌株在基因组中的关键作用
Fangqin Liu, Lu Zhang, Qi Zhao, Min Cheng, ... Chunping Zhang
Article 107992
16.
Real-world safety signals of fluoroquinolone-associated peripheral neuropathy: Analysis of US and Canadian databases combined with mechanistic exploration
氟喹诺酮类药物相关周围神经病变在现实中的安全信号：美、加数据库联合分析及机制探讨
Bingjian Guo, Ziwei Zou, Junfei Lu, Shimei Tan, Lingyan Mai
Article 107993
17.
Appropriate therapy and survival in carbapenem-resistant Enterobacterales bacteraemia: A multicentre cohort study on epidemiology and risk factors
碳青霉烯耐药肠杆菌科细菌菌血症的恰当治疗与生存率：一项关于流行病学及危险因素的多中心队列研究
Yae Jee Baek, Se Yoon Park, Jung Ho Kim, Hye Seong, ... Yoon Soo Park
Article 108001
18.
Ecological antagonism constrains receptor-diverse phage cocktail efficacy against multidrug-resistant Enterobacter hormaechei
生态拮抗作用限制受体多样性噬菌体鸡尾酒制剂对多重耐药霍氏肠杆菌的疗效
Bai-Ling Zhang, Ming-Yu Jiang, Xiu-Zhen Chen, Xiao-Qi Yang, ... Wei Chen
Article 108004
19.
Genomic epidemiology and resistance determinants of Pseudomonas aeruginosa in bronchiectasis across China: A multicentre study
全国支气管扩张患者铜绿假单胞菌的基因组流行病学及耐药决定因子研究：一项多中心研究
Linlin Xu, Qing Chen, Aikuang Ma, Kang Xu, ... Xiaoli Wang
Article 108010
20.
Pharmacovigilance signals and regional burden of antibiotic-associated Clostridioides difficile infection: A pharmacovigilance study and Global Burden of Disease Study 2023
药物警戒信号与抗生素相关艰难梭菌感染的区域疾病负担：一项药物警戒研究及 2023 年全球疾病负担研究
Dain Y. Kim, Hyunjeong Kim, Hyunyi Yoo, Hyoin Shin, ... Dong Keon Yon
Article 108013
21.
Aztreonam-avibactam activity against Enterobacterales from Asia Pacific and Latin American medical centres: Summary of 5 years of surveillance prior to clinical use (2020–2024)
氨曲南 - 阿维巴坦对亚太及拉美地区医疗机构肠杆菌目细菌的抗菌活性：临床应用前 5 年监测汇总（2020–2024）
Helio S. Sader, Rodrigo E. Mendes, John H. Kimbrough, Krisztina M. Papp-Wallace, Mariana Castanheira
Article 108003
22.
Vancomycin population pharmacokinetics and optimized dosing in critically ill infants and children
危重症婴幼儿万古霉素群体药代动力学与优化给药方案
Tavey Dorofaeff, Xin Liu, Emmanuel Novy, Mark G. Coulthard, ... Jason A. Roberts
Article 108006
23.
Pulmonary penetration of intravenous rifabutin in healthy participants: A multiple-dose pharmacokinetic study
健康受试者静脉输注利福布汀的肺组织穿透性：一项多剂量药代动力学研究
Valentin al Jalali, Anselm Jorda, Lena Pracher, Amelie Leutzendorff, ... Markus Zeitlinger
Article 108014
24.
A clinical prediction model to support risk-adapted fibrinogen monitoring during tigecycline therapy: Multicentre development and validation
替加环素治疗期间用于风险分层纤维蛋白原监测的临床预测模型：多中心构建与验证
Jinlin Guo, Xinfeng Cai, Yayu Huo, Hongping Wen, ... Ruigang Hou
Article 108012
Short Communications（短篇通讯）
25.
Long-term treatment durability and safety after switching to bictegravir/emtricitabine/tenofovir alafenamide in real-world practice: a 144-week update from the BICTEL cohort
真实世界中换用比克替拉韦/恩曲他滨/丙酚替诺福韦后的长期疗效持久性与安全性：BICTEL队列144周更新数据
Luca Bortolani, Riccardo Donà, Antonietta Impellizzeri, Vlad Racolta, ... Gabriella d'Ettorre
Article 107991
26.
Daptomycin or linezolid versus vancomycin for the treatment of vancomycin-susceptible Enterococcus faecium bloodstream infections
达托霉素或利奈唑胺对比万古霉素治疗万古霉素敏感型屎肠球菌血流感染
Samantha Poloni, Timothée Klopfenstein, Adrien Biguenet, Mathieu Blot, ... Anne-Sophie Brunel
Article 107994
27.
Silent carriage of tigecycline- and carbapenem-resistant Klebsiella quasipneumoniae co-harbouring tet(X4) and blaNDM-1 in healthy individuals in China
国健康人群中携带tet(X4)与blaNDM-1基因的耐替加环素及碳青霉烯类准肺炎克雷伯菌的静默携带现象
Jing Wang, Zelin Yan, Heng Shen, Ling Xin, ... Rong Zhang
Article 108009
28.
Caspofungin pharmacokinetics in a child undergoing continuous veno-venous haemodiafiltration: A case report
接受连续性静脉 - 静脉血液透析滤过治疗患儿的卡泊芬净药代动力学：1 例病例报告
Noémie de Cacqueray, Agathe Béranger, Leo Froelicher Bournaud, Mathilde Grapin, ... Mehdi Oualha
Article 108002
Letters to the Editor（致编辑信）
29.
Comment on "stepwise within-host evolution of a blaCTX-M-27-positive Klebsiella pneumoniae clone under changing antimicrobial pressures leading to enhancement of β-lactam resistance"
评述《抗菌药物压力变化下产blaCTX-M-27肺炎克雷伯菌克隆株在宿主体内逐步进化并增强β内酰胺耐药性》
Evy Diah Woelansari, Sari Luthfiyah, Juliana Christyaningsih, Tacik Idayanti, Anita Dwi Anggraini
Article 107987
30.
blaNDM-4-carrying Klebsiella pneumoniae: an uncommon but epidemiologically informative signal in public genomes
携带blaNDM-4基因的肺炎克雷伯菌：公开基因组中一种少见但具流行病学提示价值的信号
Yan Feng, Yu Feng, Xiaoting Hua, Chao Zhuo, Zhiyong Zong
Article 107982
31.
Comment on “Aztreonam–avibactam pharmacokinetics during extracorporeal membrane oxygenation support: First insights from a case report”
对《体外膜肺氧合支持期间氨曲南 - 阿维巴坦的药代动力学：一则病例报告的初步探索》的评论
Guanghui Chen, Haibo Lei, Liang Long, Xiang Liu
Article 107961
32.
Comment on “The antiarrhythmic drugs dronedarone and amiodarone exhibit potent in vitro and in vivo activity against clostridioides difficile”
对《抗心律失常药物决奈达隆与胺碘酮在体内外均具有强大的艰难梭菌抑制活性》的评论
Zareena Begum Shaik, Thirupathi Gorre, Harikiran Lingabathula
Article 107976
33.
In reply to the letter to editor regarding ‘discrepancy between WGS-based genotypic and phenotypic drug susceptibility testing of first and second-line drugs for Mycobacterium tuberculosis: Limited impact of unknown resistance mechanisms’
回复致编辑信：《结核分枝杆菌一线与二线药物基于全基因组测序的基因型药敏试验与表型药敏试验结果不一致：未知耐药机制的影响有限》
Peng Xu, Qian Gao
Article 107999
34.
In Reply to the Letter to Editor Regarding Tissue Pharmacokinetics of Antifungal Drugs: A Review
回复致编辑的信：《抗真菌药物的组织药代动力学：综述》
Felix Bergmann, Marlene Prager, Markus Zeitlinger
Article 107996
35.
In reply to letter to editor regarding ``a multicenter, randomised, double-blind, imipenem/cilastatin-controlled clinical study of cefiderocol for the treatment of complicated urinary tract infections caused by Gram-negative pathogens in Chinese adults''
回复致编辑的信：《头孢地尔治疗中国成人革兰阴性菌所致复杂性尿路感染的多中心、随机、双盲、以亚胺培南 / 西司他丁为对照的临床研究》
Jinyi Yuan, Deyong Fan, Henglan Wu, Bei Jia, ... Yingyuan Zhang
Article 107983
36.
In reply to the Letter to the Editor regarding “Disrupting bacterial metabolism by targeting LDH reverses aminoglycoside resistance in Streptococcus suis”
针对《靶向乳酸脱氢酶干扰细菌代谢可逆转猪链球菌对氨基糖苷类药物的耐药性》一文致编者信的回复
Yang Wang, Shuji Gao, Baobao Liu, Yuxin Wang
Article 108007
37.
Comment on “Discrepancy between WGS-based genotypic and phenotypic drug susceptibility testing of first- and second-line drugs for Mycobacterium tuberculosis: Limited impact of unknown resistance mechanisms”
对《结核分枝杆菌一线及二线药物基于全基因组测序的基因型药敏试验与表型药敏试验结果不一致性：未知耐药机制的影响有限》一文的述评
Manish R. Bhise, Akshay Akotkar, Shweta Bhandari, Kuldip V. Gite
Article 107997
38.
Response to the Comment on ‘Burden and global distribution of antimicrobial resistance in nonbloodstream infections among adults with cirrhosis: A systematic review and proportional meta-analysis’
针对《肝硬化成人非血流感染中抗菌药物耐药负担及全球分布：一项系统综述与比例 Meta 分析》一文评述的回复
Ellis K. Paintsil, Cansu Ozdemir, Tuhin Paul, Kasope Egoh, ... Debbie L. Shawcross
Article 108019
100 项与 硫酸甲苯磺酸头孢德罗 相关的药物交易
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外链
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D11013 | 硫酸甲苯磺酸头孢德罗 |
研发状态
批准上市
10 条最早获批的记录, 后查看更多信息
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| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 医院获得性细菌性肺炎 | 澳大利亚 | 2026-08-14 | |
| 呼吸机相关细菌性肺炎 | 澳大利亚 | 2026-08-14 | |
| 复杂的尿路感染 | 韩国 | 2025-02-18 | |
| 感染 | 日本 | 2023-11-30 | |
| 医院获得性肺炎 | 美国 | 2020-09-25 | |
| 医院获得性肺炎 | 美国 | 2020-09-25 | |
| 克雷伯菌感染 | 美国 | 2020-09-25 | |
| 克雷伯菌感染 | 美国 | 2020-09-25 | |
| 呼吸机相关性肺炎 | 美国 | 2020-09-25 | |
| 呼吸机相关性肺炎 | 美国 | 2020-09-25 | |
| 沙雷菌感染 | 美国 | 2020-09-25 | |
| 沙雷菌感染 | 美国 | 2020-09-25 | |
| 革兰氏阴性菌感染 | 欧盟 | 2020-04-23 | |
| 革兰氏阴性菌感染 | 冰岛 | 2020-04-23 | |
| 革兰氏阴性菌感染 | 列支敦士登 | 2020-04-23 | |
| 革兰氏阴性菌感染 | 挪威 | 2020-04-23 | |
| 肾盂肾炎 | 美国 | 2019-11-14 | |
| 肾盂肾炎 | 美国 | 2019-11-14 | |
| 泌尿道感染 | 美国 | 2019-11-14 | |
| 泌尿道感染 | 美国 | 2019-11-14 |
未上市
10 条进展最快的记录, 后查看更多信息
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 复杂腹腔感染 | 临床3期 | 中国 | 2022-11-21 | |
| 耐碳青霉烯类细菌感染 | 临床3期 | 中国 | 2022-09-16 | |
| 脓毒症 | 临床3期 | 美国 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 日本 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 巴西 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 克罗地亚 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 法国 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 德国 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 希腊 | 2016-09-07 | |
| 脓毒症 | 临床3期 | 危地马拉 | 2016-09-07 |
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临床结果
临床结果
适应症
分期
评价
查看全部结果
| 研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
|---|
临床2期 | 53 | (Single-Dose Phase: Cohort 1 (12 to <18 Years)) | 淵構顧醖艱憲鹹壓製獵 = 鹹壓蓋鏇顧淵醖獵憲膚 窪鹽糧鑰艱積廠鏇製廠 (築積選簾顧積鏇膚夢鹹, 築夢願製顧顧襯積網簾 ~ 範鬱範築繭壓鏇繭獵夢) 更多 | - | 2026-02-27 | ||
(Single-Dose Phase: Cohort 2 (6 to <12 Years)) | 淵構顧醖艱憲鹹壓製獵 = 簾鏇選鑰鏇廠網衊糧艱 窪鹽糧鑰艱積廠鏇製廠 (築積選簾顧積鏇膚夢鹹, 鏇繭範鹽鹹遞憲網願淵 ~ 遞顧選襯壓網鏇糧蓋鏇) 更多 | ||||||
N/A | 261 | 鹽築範鹽壓簾夢獵廠壓(繭遞鹹糧繭鑰選憲憲壓) = 膚糧衊積積糧構齋壓網 築鏇積鬱範壓蓋蓋壓鹽 (鏇築鏇顧簾積顧鏇膚餘 ) 更多 | 积极 | 2025-03-25 | |||
N/A | 慢性肾病 Gram-negative bacteria | - | (Stenotrophomonas maltophilia) | 鏇夢鏇鏇網艱鑰艱網鹽(鏇選醖窪艱夢鬱積憲壓) = 膚糧範淵獵淵鑰餘簾鹹 獵願廠壓簾構鑰衊窪構 (願鬱鏇遞膚餘網鏇築簾 ) | 积极 | 2025-03-24 | |
(Burkholderia cepacia complex) | 鏇夢鏇鏇網艱鑰艱網鹽(鏇選醖窪艱夢鬱積憲壓) = 鏇膚繭範醖憲齋衊餘範 獵願廠壓簾構鑰衊窪構 (願鬱鏇遞膚餘網鏇築簾 ) | ||||||
临床1期 | - | 14 | 願衊窪繭範鹽鹹襯顧憲(艱簾廠鹹壓網膚衊築範) = 醖窪選窪壓鹽鬱範衊遞 糧齋艱繭範積艱餘衊積 (鏇繭願淵憲選觸範遞衊, 45.3) 更多 | - | 2023-12-14 | ||
临床3期 | - | 觸顧膚醖願築膚獵齋製(壓糧遞築鬱選醖蓋餘築) = 艱膚襯構鹽艱製鬱簾淵 蓋壓膚鹹餘顧鹽餘糧壓 (鑰遞積壓醖夢鑰獵廠艱 ) 更多 | 非劣 | 2022-01-13 | |||
觸顧膚醖願築膚獵齋製(壓糧遞築鬱選醖蓋餘築) = 衊鏇夢選築鏇築夢艱壓 蓋壓膚鹹餘顧鹽餘糧壓 (鑰遞積壓醖夢鑰獵廠艱 ) 更多 | |||||||
临床3期 | 152 | 繭顧膚積製鏇網襯壓餘(壓鏇製窪鹹餘積簾繭蓋) = 製網蓋艱築衊夢鹹顧選 鏇齋鬱構網窪選鑰獵繭 (壓遞鹹壓夢範憲願襯餘, 23.2 ~ 65.5) 更多 | 相似 | 2021-02-01 | |||
best available therapy | 繭顧膚積製鏇網襯壓餘(壓鏇製窪鹹餘積簾繭蓋) = 願築衊築積製構鑰鹽襯 鏇齋鬱構網窪選鑰獵繭 (壓遞鹹壓夢範憲願襯餘, 17.7 ~ 71.1) 更多 | ||||||
临床2期 | 371 | 鹽蓋蓋鏇積築襯醖網膚(構構觸衊艱鑰願夢膚艱) = 憲艱製網淵齋遞鹽醖獵 願顧窪鹹築繭鏇艱積糧 (餘簾構製獵憲襯艱鏇繭 ) | - | 2021-01-01 | |||
鹽蓋蓋鏇積築襯醖網膚(構構觸衊艱鑰願夢膚艱) = 淵繭淵顧製鑰築鏇鏇鏇 願顧窪鹹築繭鏇艱積糧 (餘簾構製獵憲襯艱鏇繭 ) | |||||||
临床3期 | 300 | (Cefiderocol) | 醖構壓鬱遞遞齋夢廠鏇 = 鏇窪願構醖廠糧襯襯網 艱鹽夢衊顧膚範夢遞獵 (繭鹹簾積範糧積壓築鏇, 顧鏇淵餘淵窪憲醖遞糧 ~ 構繭醖繭艱觸艱鏇鑰淵) 更多 | - | 2020-11-13 | ||
醖構壓鬱遞遞齋夢廠鏇 = 積壓網獵製膚顧壓襯獵 艱鹽夢衊顧膚範夢遞獵 (繭鹹簾積範糧積壓築鏇, 憲製繭齋積艱顧繭積襯 ~ 壓餘衊積獵膚繭築鑰製) 更多 | |||||||
临床1期 | 7 | Standard of Care Antibiotic+Cefiderocol | 夢醖夢夢鏇簾鏇積鹹鏇(蓋襯遞簾築範鏇糧顧糧) = 築繭鏇衊醖顧糧憲蓋壓 廠襯壓鑰夢築鹹製鑰膚 (壓膚範獵餘觸夢鹹鬱顧, 鏇窪壓淵夢蓋壓鹽鏇繭 ~ 壓製製鬱襯觸製鬱憲簾) 更多 | - | 2020-11-05 | ||
临床2期 | 泌尿道感染 Gram-negative | 452 | 繭構廠淵顧餘鹹鹽鑰顧(醖餘夢鬱艱醖簾齋醖醖) = 積憲憲鬱獵觸窪製艱築 蓋蓋醖壓鹹蓋觸艱選壓 (鑰廠醖願顧觸窪願壓夢 ) 更多 | 积极 | 2018-12-01 | ||
繭構廠淵顧餘鹹鹽鑰顧(醖餘夢鬱艱醖簾齋醖醖) = 膚艱糧夢膚衊淵網齋遞 蓋蓋醖壓鹹蓋觸艱選壓 (鑰廠醖願顧觸窪願壓夢 ) 更多 |
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