Netupitant/Palonosetron Hydrochloride

HONG KONG, Nov. 7, 2024 /PRNewswire/ -- On November 5, the 7th China International Import Expo (CIIE) opened at the National Exhibition and Convention Center in Shanghai. As a seven-time attendee of the CIIE, Fosun showcased the latest achievements in innovation and global operations at its Fosun Pharma booth in Hall 7.1, featuring cutting-edge medical devices and innovative pharmaceuticals that made their debut in China. Guo Guangchang, Chairman of Fosun International, remarked, "Over the past seven years, CIIE has improved every year, becoming a window for China to build a new development framework, a platform for high-level openness, and an international public product for global sharing. Fosun has been a participant, witness, and beneficiary of the CIIE. Leveraging the CIIE platform, our long-term innovations have continually been put into practice, transforming many 'exhibits' into 'products', and converting many overseas partners from 'exhibitors' into 'investors'. This year, we continue to showcase our latest achievements in integrated innovation in the medical device and health sector, including several 'world's firsts' and 'China's firsts'. We firmly believe that China remains a significant opportunity for global development. Together with more overseas companies and global partners, we will promote more cutting-edge innovations to take root in China, moving forward and achieving mutual success on the grand stage of the CIIE." Stars of CIIE Taking Root, Transforming Ion from "Exhibit" to "Product" Healthcare is one of Fosun's main businesses. With CIIE's "spillover effect," several star products from Fosun, supported by the CIIE "accelerator" effect, have successfully entered the market to serve Chinese patients, transforming from "exhibits" into "products". This year, following the popular da Vinci Surgical System, the Ion Robotic Bronchoscopy made its CIIE debut after receiving domestic approval. Since its first appearance at the CIIE in 2019, Ion caught the attention of visitors. By the end of 2022, Ion entered the National Medical Products Administration's 'Green Channel' for innovative products and gained approval in March 2024, with the first commercial application completed in September. Lung cancer is considered the leading cause of cancer deaths, with 1.06 million new cases in China in 2022. The five-year survival rate is only 19.7%, and bronchoscopy is a key diagnostic tool for early lung cancer detection. The Ion bronchoscopy navigation control system offers innovative features for precise, convenient clinical diagnosis, providing new options for patients. By the third quarter of this year, 736 Ion systems had been installed globally, with over 150,000 Ion procedures performed. Outside the CIIE exhibition hall, Fosun is accelerating the localization of advanced medical devices. In June this year, Intuitive Fosun's headquarter industrial base was launched in Shanghai, marking Intuitive's largest R&D, production, and training center in the Asia-Pacific region. At this base, in addition to the Ion shape-sensing bronchoscopy control system, advanced products and core components, including the da Vinci surgical robot, are gradually achieving "Made in China, joint R&D, and global sales." Accelerating Integrated Innovation to Lead in Neurological Disease Treatment Transformation Fosun has long committed to investing in cutting-edge areas of healthcare, fostering a continuous stream of breakthrough "solid achievements" through an open innovation ecosystem involving independent R&D, collaborative development, licensing, and industry investment. These innovations are continually transformed into new drivers of growth. At this year's CIIE, Fosun introduced several latest products that are leading industry transformation. In the field of neurological disease treatment, especially for conditions like essential tremor and Parkinson's disease, patients have long faced challenges with unmet clinical needs. Traditional drug and surgical treatments often have limitations, but advancements in non-invasive treatment technologies have brought new hope to these patients. Fosun has actively responded to this unmet clinical need. At this year's CIIE, the new V2 model of the CNS (Central Nervous System) innovative treatment technology, the V2 model of "Exablate Neuro FUS system" made its debut in China, generating high expectations within the industry. This new model has already received CE certification in Europe and FDA approval in the United States and submitted a registration application to China's National Medical Products Administration in 2024. The V2 model's innovation lies in providing a non-invasive surgical solution for clinically drug-resistant essential tremor and tremor-dominant Parkinson's disease, while also being compatible with a broader range of MRI models, further enhancing the accessibility of this technology. Last year, Fosun, in partnership with Insightec, showcased the "Exablate Neuro" at CIIE, drawing much attention and continuous interest in collaboration. Leveraging the CIIE's "spillover effect", Fosun Pharma and Insightec established a joint venture, Fosun-Insightec, in February this year. The venture is focused on the marketing and developing clinical efforts of Exablate Neuro FUS system in improving the lives of patient living with essential tremor and Parkinson's disease, working to help them regain their quality life and wellbeing. Focusing on innovating to meet real customer needs is a core methodology for Fosun. Data shows that Fosun has made long-term investments in technological innovation, with an investment of RMB 3.5 billion in the first half of this year. Connecting Globally to Enhance Accessibility of Innovative Drugs, Benefiting more Patients Leveraging the CIIE's openness, Fosun also presented innovative products focused on solid tumors, hematological tumors, and immune-inflammatory conditions. Fosun's seven-year journey at CIIE has facilitated the introductions of global products and enabled the export of local innovations to benefit more patients worldwide. In 2017, Fosun introduced China's first CAR-T cell therapy product, Yi Kai Da (ejilunsai injection). Since then, by continuously participating in the CIIE, Fosun has enabled the public to gain an in-depth understanding of this advanced therapy. At this year's CIIE, Fosun highlighted Yi Kai Da's latest developments in the "accessibility and treatability" in lymphoma treatment. Yi Kai Da is now included in over 110 urban customized commercial health insurances and more than 80 commercial insurances, created a new path of payment mode for patients; and over 170 high-standard treatment centers across 28 regions in China providing treatments for over 900 lymphoma patients, achieving revolutionary innovative breakthroughs for cancer care. As a global company rooted in China, Fosun has an extensive industrial presence in over 35 countries and regions worldwide, with robust global R&D capabilities and impressive progress. This year, Fosun also showcased several innovative products, including the world's first and only dual-channel fixed-dose combination oral formulation, Akynzeo® oral (Netupitant and Palonosetron hydrochloride), which blocks both NK-1 and 5-HT3 receptors; the immunoglobulin Thymoglobulin® for improving transplant patient outcomes; the world's first oral targeted medication for psoriasis, Otezla® (apremilast tablets); a new third-generation COMT inhibitor Ongentys® (Opicapone) for managing symptom fluctuations in adult Parkinson's disease patients; and Parsabiv® (Etelcalcetide Hydrochloride Injection), the only peptide-based calcimimetic for treating secondary hyperparathyroidism in adult dialysis patients with chronic kidney disease. Guo Guangchang concluded, "Participating in CIIE has been a top priority for Fosun for seven consecutive years. We have witnessed CIIE become a crucial platform for global companies to share in China's development opportunities and deepened our global partnerships through this platform. We believe the CIIE stage will continue to expand, and Fosun's journey of innovation and globalization will grow broader." SOURCE Fosun WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED

11月5日，第七届中国国际进口博览会在国家会展中心（上海）盛大开幕。复星医药连续七年奔赴进博之约，在7.1医疗器械及医药保健展区B3-02展台，以其卓越的创新成果和全球化布局，展现了其致力于成为全球领先的医疗创新整合者的强大实力和深远影响。 复星国际董事长郭广昌表示：“七年来，进博会越办越好，已成为中国构建新发展格局的窗口、推动高水平开放的平台和全球共享的国际公共产品。复星是进博会的参与者、见证者，更是受益者。依托进博会平台，我们长期深耕的创新成果持续落地，一批前沿创新从‘展品’变‘商品’，很多海外合作伙伴从‘展商’变‘投资商’。今年，我们继续在医疗器械及医药保健区展示复星一年来在全球整合式创新方面取得的最新成果，其中包括多个‘全球首款’‘中国首个’产品。我们坚信中国始终是世界发展的重要机遇，我们将携手更多海外成员企业和全球合作伙伴，推动更多前沿创新在中国落地生根，在进博会的大舞台上相向而行、相互成就。” 进博明星落地生根，Ion由“展品”变“商品” 复星医药在七年进博之旅过程中，“展品变商品”“展商变投资商”的生动“进博故事”不断涌现，充分印证了进博会“溢出效应”所带来的产业动能。继往届“网红产品”达芬奇手术机器人之后，今年，直观复星又一“明星产品”Ion支气管镜机器人迎来了国内获批上市后的进博首秀。 2019年，Ion在进博会首次展出。在进博会“溢出效应”的推动下，Ion逐渐被大众及专业人士熟知，并加速实现由“展品”到“商品”的转变。2022年底，通过国家药监局评审进入创新产品“绿色通道”。2024年3月，Ion获得国家药品监督管理局批准上市，同年9月直观复星实现了首台Ion商业装机并顺利完成了首例商业应用。截至2024年第二季度，全球已安装了736套Ion，实施了超过15万例Ion手术，在全球临床专家和患者眼中具有良好口碑。 随着中国医疗市场的持续扩大和升级，直观复星的本土化战略将进一步推动医疗技术的创新和普及，满足日益增长的高端医疗服务需求，为中国患者带来更优质的治疗方案。2024年6月，直观复星总部及产业化基地在创新高地上海正式启用，该中心集研发、生产和培训等功能为一体，生产包括达芬奇Xi手术机器人、Ion形状感知支气管镜操作控制系统和相关零部件产品，每年可为4000多位医护人员提供国际认证的机器人辅助手术培训。 整合创新加速转化，引领神经系统疾病诊疗新革命 复星医药通过自主研发、合作开发、许可引进、产业投资等开放式创新研发生态，一批批突破性“硬成果”破壳诞生，持续转化为发展新动能。今年进博会，多个引领行业变革的最新产品亮相。 在神经系统疾病的治疗领域，尤其是特发性震颤和帕金森病等，患者长期以来面临着临床需求未得到充分满足的挑战。传统的药物治疗和手术治疗往往存在局限性，而无创治疗技术的发展为这些患者带来了新的希望。 复星医药积极响应这一临床未满足的需求，引进的革命性的磁波刀全新V2机型迎来中国首展。这一全新机型已获得欧洲CE认证和美国FDA批准，并于2024年正式递交中国国家药品监督管理局（NMPA）注册申请。该机型不仅为临床治疗药物难治性特发性震颤和以震颤为主型的帕金森病提供无创手术方案，同时V2机型可适配更多品牌型号磁共振机型，进一步扩大该技术的可及性。 复星医视特是由复星医药与全球无创治疗领域的领军企业INSIGHTEC（医视特）于2024年在中国成立的合资公司，其核心产品——磁共振引导聚焦超声脑部治疗系统（磁波刀），已经成为全球脑部无创治疗的革命性标志。全球范围内，该系统已经成功治疗了超过20,000例特发性震颤及帕金森病患者。与传统的药物治疗、开颅手术或微创手术相比，“磁波刀”提供了一种无创、精准、安全的全新临床治疗方案，标志着复星医药在将尖端科技转化为实际医疗解决方案方面迈出了坚实的步伐。 链接全球 惠及患者 提升创新药品可及性 借助进博会这一国际展示平台，复星医药链接全球市场机遇，致力于提升多款创新产品和疗法的可及性，为广大中国患者带来福音。在实体瘤、血液瘤、免疫炎症等核心治疗领域，复星医药重点展出了其创新产品，展现了公司在提升患者生活质量方面的坚定承诺。 七年进博历程，也见证了CAR-T细胞治疗产品奕凯达®（阿基仑赛注射液）在可愈可及方面的显著进步。目前，奕凯达®已纳入超过110个城市惠民保和超过80款商业保险，为患者开辟了多元化的创新支付路径。全国已有28个省区市的170家奕凯达®高标准治疗中心，为超过900位淋巴瘤患者提供了治疗，实现了肿瘤治疗领域的革命性创新突破。 此外，复星医药还展出了全球首个且唯一同时阻断NK-1受体和5-HT3受体的双通道固定剂量组合口服复方制剂奥康泽®（奈妥匹坦帕洛诺司琼胶囊）、用于改善接受移植患者预后的复可舒®（抗人T细胞兔免疫球蛋白）、全球首款银屑病口服靶向药物欧泰乐®（阿普米司特片）、用于治疗成人帕金森病患者症状波动的全新第三代COMT抑制剂欧捷能®（奥吡卡朋）、以及用于治疗慢性肾病接受血液透析的成人患者的继发性甲状腺功能亢进症的唯一的多肽类拟钙剂旁必福®（盐酸依特卡肽注射液）。这些全球领先的创新药品的展出，不仅彰显了复星医药在新药研发领域的领先地位，也体现了公司在提升药品可及性方面的不懈努力。 “参加进博会，是复星连续七年的置顶事项。一路走来，我们见证了进博会成为全球共享中国发展机遇的重要平台，也通过这个重要的平台进一步深化了与全球企业的合作。我们相信进博会的舞台会越来越宽广，复星的创新和全球化之路也会越走越宽广。”郭广昌表示。