The partnership aims to advance the idiopathic pulmonary fibrosis therapy into a Phase II trial. Credit: Andrey_Popov/Shutterstock.
Mediar Therapeutics has entered a global licensing agreement with Eli Lilly and Company to progress the human immunoglobulin G1(IgG1) antibody, MTX-463, into a Phase II trial for the treatment of idiopathic pulmonary fibrosis (IPF).
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2022: So far In Venture Capital
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GlobalData’s whitepaper analyzes which sectors PE/VC firms have been investing in, looking at Technology, Media, and Telecom, with these sectors recording $356 billion and a deal volume of over 10,000 deals in 2022. Healthcare, Financial Services, Business & Consumer Services, and Construction sectors have also seen high investment activity by PE/VC firms, recording a deal value of over $70 billion each.
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Mediar will receive $99m, consisting of an upfront payment and near-term milestones, with a further potential $687m from future development and commercialisation, and royalties and net sales milestones from future product sales.
In a recently completed Phase I trial of healthy volunteers, the therapy was found to be well-tolerated and to engage’ WNT1-inducible signalling pathway protein 1 (WISP1) at all tested doses.
The upcoming Phase II trial will assess the pharmacokinetics, efficacy and safety of the therapy in IPF subjects. Mediar plans to commence the trial in the first half of 2025 and will be responsible for its conduct.
Post-Phase II, Lilly is set to take over further clinical development and commercialisation efforts.
Mediar Therapeutics CEO Rahul Ballal stated: “This collaboration supports our unique myofibroblast-directed approach to treating fibrotic diseases and our mission to bring first-in-class therapies to patients with high unmet medical need.”
In addition to MTX-463, Mediar is independently progressing two other proprietary programmes targeting fibrotic disorders.
In a separate announcement, Eli Lilly has revealed its plans to establish a new global capability centre in Hyderabad, India, as reported by
The Economic Times
.
The Lilly Capability Centre India (LCCI) Hyderabad is set to focus on enhancing Lilly’s digital capabilities in areas such as artificial intelligence, automation, software product engineering and cloud computing.
Recruitment is already in progress for the centre, which will be operational by mid-2025. It is the company’s second such facility in India, following LCCI Bengaluru’s launch in 2016.
In December 2024, Eli Lilly’s Zepbound (tirzepatide) received a
label expansion from the US Food and Drug Administration
to treat adults with obesity and moderate to severe obstructive sleep apnoea.
Free Report
2022: So far In Venture Capital
Global investment in 2022 has been majorly dominated by North America, Europe, and Asia Pacific, whereas the Middle East, and South and Central America have recorded low investments comparatively. In light of this, Europe and North America have been identified as the major destinations for Private Equity and Venture Capital (PE/VC) investments.
GlobalData’s whitepaper analyzes which sectors PE/VC firms have been investing in, looking at Technology, Media, and Telecom, with these sectors recording $356 billion and a deal volume of over 10,000 deals in 2022. Healthcare, Financial Services, Business & Consumer Services, and Construction sectors have also seen high investment activity by PE/VC firms, recording a deal value of over $70 billion each.
But what can this mean for you?
Understand how the Deals Database on GlobalData Explorer can be leveraged to:
Track the Aggregate Investment Volumes in PE/VC-Stage firms across geographies and sectors, in addition to viewing the specific deals that drove these volumes
Identify the top investors already active in any sector-Geography combinations
Assess the Performance of Financial and Legal Advisors, supporting the Dealmaking in any segment of choice (Customizable League tables)
Understand what is driving the PE/VC fundraising (Deal Rationale)
Consult our full report here and optimize your business strategy.
Thank you.
You will receive an email shortly. Please check your inbox to download the Report.
By GlobalData
Submit
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