Contera Pharma ApS

Notice of Dissolution and Filing of Claims Contera Pharma A/S has decided to close the branch office in Korea and consolidate all activities in the Headquarter in Denmark. The formal notice of dissolution and filing of claims can be found below. The Company has resolved to dissolve at the Board of Directors meeting in 2024/ […] Notice of Dissolution and Filing of Claims Contera Pharma A/S has decided to close the branch office in Korea and consolidate all activities in the Headquarter in Denmark. The formal notice of dissolution and filing of claims can be found below. The Company has resolved to dissolve at the Board of Directors meeting in 2024/ […] [Hørsholm, September 6, 2024] – Contera Pharma A/S, a clinical-stage biotech company developing innovative therapies to treat neurological disorders, is pleased to announce key changes to its leadership team. These strategic appointments underscore the company’s commitment to advancing clinical excellence, financial integrity, and scientific innovation. Contera Pharma has welcomed Dr. Anne Birk Østerskov as Chief […] [Hørsholm, May 21st, 2024] – Contera Pharma A/S, a biotech company developing innovative therapies to treat neurological disorders, announce topline results from the ASTORIA Phase IIb trial of JM-010 in people suffering from dyskinesia in Parkinson´s disease. The main objectives of the trial were to investigate efficacy and safety of two doses of JM-010, compared […] [Hørsholm, January 17th, 2024] – Contera Pharma A/S, a biotech company developing innovative therapies to treat neurological disorders, announce enrolment of the last patient in its Phase 2b clinical trial ASTORIA. The trial aims to evaluate the efficacy of JM-010, a novel therapeutic solution designed to specifically address the pathophysiology underlying Parkinson’s disease dyskinesia. This […] Contera Pharma, a biotech company developing innovative therapies to treat neurological disorders, and BDD Pharma, a drug delivery company specializing in modified and controlled release oral formulations, announce dosing of first subject in a Phase 1 pharmacoscintigraphic study in healthy volunteers. The study will evaluate a novel delayed-release, dual pulse levodopa / carbidopa tablet (CP-012), […]

[Hørsholm, September 6, 2024] – Contera Pharma A/S, a clinical-stage biotech company developing innovative therapies to treat neurological disorders, is pleased to announce key changes to its leadership team. These strategic appointments underscore the company’s commitment to advancing clinical excellence, financial integrity, and scientific innovation. Contera Pharma has welcomed Dr. Anne Birk Østerskov as Chief Medical Officer to enhance its clinical development efforts, promoted Kathrine Baisgaard Bjerno to Chief Financial Officer to drive Contera Pharma’s financial strategy and ensure seamless investor relations, and advanced Søren Rasmussen to Chief Scientific Officer to drive the discovery of groundbreaking therapies for neurological diseases. Anne Birk Østerskov brings over a decade of experience from Novo Nordisk, LEO Pharma, and Hedia. Anne has an extensive background in clinical drug development, having led global clinical programs and played a pivotal role in establishing a Medical & Science Hub in the U.S. Her expertise in clinical development, regulatory strategy, and strategic leadership will be instrumental in driving Contera Pharma’s pipeline towards commercialization and improving patient care. Kathrine Baisgaard Bjerno joined Contera Pharma earlier in 2024 as VP – Finance following more than a decade at H. Lundbeck A/S in positions across Finance, Executive Management support and Business Development. Leveraging her experience from finance, M&A valuations and from leading company-wide strategy projects, Kathrine will drive Contera Pharma’s financial strategy, ensure robust financial planning to support critical milestones and facilitate seamless investor relations. Søren Vestergaard Rasmussen served as Vice President and Head of Research Technology & Innovation at Contera, where he has been instrumental in establishing Contera Pharma’s preclinical project portfolio within CNS drug discovery. His previous tenure at Roche included roles as Senior Principal Scientist and Technology Officer, where he advanced Roche’s antisense technology platforms within CNS and as technical project lead progressed antisense oligonucleotides to clinical development. Søren’s innovative mindset and leadership in drug discovery will drive Contera Pharma’s scientific strategy and development of novel treatments. Anders Brandt Elvang continues in his current role as COO & Head of Business Development. “We are thrilled to bring together our new leadership team, which brings decades of expertise. We have assembled a dynamic team with a strong ambition to advance our mission of developing transformative treatments for neurological disorders”, said Thomas Sager, CEO, Contera Pharma. “The new management team will stay focused on our key deliverables on progressing our advanced pipeline while further consolidating our RNA technology platform and the unique projects we have – while doing this we will continue our search for additional business partners”. About Contera Pharma A/S Contera Pharma A/S is focused on developing new treatments for people suffering from neurological disorders. Contera Pharma’s science is based on a precision medicine approach integrating external and internal data sources to support rational selection of human disease-validated drug discovery targets to identify novel pipeline opportunities within neurological disorders. The company’s lead assets, CP-012, is currently approaching Phase Ib clinical testing for Parkinson’s disease nocturnal immobility and morning akinesia. Contera Pharma was founded in 2010 and is headquartered in Hørsholm, Denmark.

[Hørsholm, May 21st, 2024] – Contera Pharma A/S, a biotech company developing innovative therapies to treat neurological disorders, announce topline results from the ASTORIA Phase IIb trial of JM-010 in people suffering from dyskinesia in Parkinson´s disease. The main objectives of the trial were to investigate efficacy and safety of two doses of JM-010, compared to placebo, in people with Parkinson´s disease dyskinesia. The primary efficacy endpoint, reduction of dyskinesia as assessed by the Unified Dyskinesia Rating Scale (UDysRS) was not met. At 12 weeks, nominal reductions of 0.3 and 4.2 points in change from baseline UDysRS total scores versus placebo were observed for the two JM-010 doses, respectively; however, the differences were not statistically significant. Both doses of JM-010 were well-tolerated and no serious treatment-related adverse events were observed in the study. “Unfortunately, the primary endpoint assessing reduction in dyskinesia as evaluated by the UDysRS was not met. The ASTORIA trial was well conducted, and we will look into the results in more detail to fully understand the outcome of the study. Meanwhile, we would like to express our sincere gratitude to the patients, investigators and our JM-010 alliance partner Bukwang for their commitment to the study“, said Kenneth Vielsted Christensen, CSO and Head of R&D, Contera Pharma. Further analysis of the full dataset from ASTORIA including secondary endpoints is currently ongoing and full disclosure of the detailed results from the Phase IIb trial will be published at future scientific congresses and peer-reviewed publications. “We are of course disappointed with the outcome of the ASTORIA trial”, said Thomas Sager, CEO, Contera Pharma. “Despite this setback, we remain fully committed and will continue advancing our other clinical stage program CP-012 addressing morning akinesia in Parkinson´s disease and are excited about the progress we see in our preclinical pipeline within rare neurological disorders.” About the study The ASTORIA trial is “A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study in Parkinson’s Disease Patients with Moderate to Severe Dyskinesia to Assess the Efficacy and Safety/Tolerability of Two Dose Combinations of JM-010”. The study targets 81 Parkinson’s disease patients and involves 38 clinical sites across Europe and Asia, including the following countries: Germany, France, Italy, Spain and Slovakia and Korea. More information on the study can be found on clinicaltrials.gov: NCT03956979 About Contera Pharma A/S Contera Pharma A/S is focused on developing new treatments for people suffering from neurological disorders. Contera Pharma’s science is based on a precision medicine approach integrating external and internal data sources to support rational selection of human disease-validated drug discovery targets to identify novel pipeline opportunities within neurological disorders. The company’s lead assets, JM-010, is currently in Phase IIb clinical testing for Parkinson’s disease dyskinesia. Contera Pharma was founded in 2010 and has offices in Hørsholm, Denmark and Seoul, South-Korea.