Bedaquiline Fumarate

新的一年的“双通道”管理药品名单公布了。 12 月 31 日，上海市药事所发布了上海市纳入“双通道”管理的药品名单，将于 2026 年正式执行，共有 702 个品种（附后），比 2025 年增加了 110 个。 2025 年是 592 个，2024 年是 503 个（详情见 MRCLUB 历史消息：503个药品，纳入“双通道”管理）。 因品种较多，手机浏览想查找自己的品种，可以用公众号页面的搜索功能：选择当前页面右上三个小圆点“···”，在弹出的TAB面板上选择“查找页面内容”按钮，输入药品名字即可。 上海市“双通道”管理药品名单 (2026 年执行) # 药品名称 1 达格列净片 2 盐酸奥普力农注射液 3 米拉贝隆缓释片 4 西他沙星片 5 富马酸贝达喹啉片 6 阿昔替尼片 7 甲磺酸仑伐替尼胶囊 8 枸橼酸伊沙佐米胶囊 9 培门冬酶注射液 10 恩扎卢胺软胶囊 11 特立氟胺片 12 注射用英夫利西单抗 13 乙磺酸尼达尼布软胶囊 14 盐酸鲁拉西酮片 15 布南色林片 16 依达拉奉氯化钠注射液 17 盐酸左沙丁胺醇雾化吸入溶液 18 他氟前列素滴眼液 19 钆特醇注射液 20 钆布醇注射液 21 注射用艾普拉唑钠 22 奥美拉唑碳酸氢钠干混悬剂(I) 23 奥美拉唑碳酸氢钠干混悬剂(Ⅱ) 24 富马酸伏诺拉生片 25 替戈拉生片 26 甲磺酸多拉司琼注射液 27 昂丹司琼口溶膜 28 奈妥匹坦帕洛诺司琼胶囊 29 甘草酸单铵半胱氨酸氯化钠注射液 30 精氨酸谷氨酸注射液 31 门冬氨酸鸟氨酸颗粒 32 利那洛肽胶囊 33 磷酸钠盐散 34 德谷门冬双胰岛素注射液 35 德谷胰岛素利拉鲁肽注射液 36 盐酸二甲双胍缓释片(Ⅲ) 37 二甲双胍恩格列净片(Ⅰ) 38 阿卡波糖咀嚼片 39 艾塞那肽注射液 40 利拉鲁肽注射液 41 利司那肽注射液 42 贝那鲁肽注射液 43 度拉糖肽注射液 44 聚乙二醇洛塞那肽注射液 45 司美格鲁肽注射液 46 艾托格列净片 47 脯氨酸恒格列净片 48 西格列他钠片 49 艾地骨化醇软胶囊 50 麦格司他胶囊 51 盐酸乙酰左卡尼汀片 52 注射用维得利珠单抗 53 阿加糖酶α注射用浓溶液 54 司来帕格片 55 铝镁匹林片(Ⅱ) 56 氯吡格雷阿司匹林片 57 曲前列尼尔注射液 58 注射用重组人组织型纤溶酶原激酶衍生物 59 注射用重组人尿激酶原 60 注射用阿替普酶 61 注射用重组人TNK组织型纤溶酶原激活剂 62 甲苯磺酸艾多沙班片 63 注射用甲磺酸萘莫司他 64 注射用重组人凝血因子Ⅶa 65 重组人血小板生成素注射液 66 注射用尖吻蝮蛇血凝酶 67 马来酸阿伐曲泊帕片 68 人凝血因子Ⅸ 69 艾曲泊帕乙醇胺片 70 海曲泊帕乙醇胺片 71 注射用罗普司亭 72 异麦芽糖酐铁注射液 73 罗沙司他胶囊 74 注射用罗特西普 75 达依泊汀α注射液 76 多种油脂肪乳(C6～24)注射液 77 复方氨基酸注射液(18AA-Ⅴ-SF) 78 复方氨基酸注射液(14AA-SF) 79 中长链脂肪乳/氨基酸(16)/葡萄糖(36%)注射液 80 结构脂肪乳(20%)/氨基酸(16)/葡萄糖(13%)注射液 81 小儿多种维生素注射液(13) 82 艾考糊精腹膜透析液 83 门冬氨酸钾镁木糖醇注射液 84 醋酸艾替班特注射液 85 拉那利尤单抗注射液 86 注射用重组人脑利钠肽 87 丹参酮ⅡA磺酸钠注射液 88 瑞加诺生注射液 89 非奈利酮片 90 波生坦片 91 波生坦分散片 92 利奥西呱片 93 马昔腾坦片 94 注射用盐酸兰地洛尔 95 盐酸艾司洛尔氯化钠注射液 96 比索洛尔氨氯地平片 97 氨氯地平叶酸片(II) 98 阿利沙坦酯片 99 阿齐沙坦片 100 美阿沙坦钾片 101 沙库巴曲缬沙坦钠片 102 非诺贝酸片 103 海博麦布片 104 依洛尤单抗注射液 105 阿利西尤单抗注射液 106 本维莫德乳膏 107 度普利尤单抗注射液 108 克立硼罗软膏 109 阿布昔替尼片 110 克霉唑阴道膨胀栓 111 注射用醋酸奥曲肽微球 112 醋酸兰瑞肽缓释注射液(预充式) 113 注射用甲苯磺酸奥马环素 114 苹果酸奈诺沙星胶囊 115 苹果酸奈诺沙星氯化钠注射液 116 注射用头孢唑林钠/氯化钠注射液 117 注射用头孢美唑钠/氯化钠注射液 118 注射用头孢呋辛钠/氯化钠注射液 119 注射用头孢他啶/5%葡萄糖注射液 120 注射用头孢他啶/氯化钠注射液 121 小儿法罗培南钠颗粒 122 盐酸头孢卡品酯颗粒 123 吗啉硝唑氯化钠注射液 124 注射用磷酸左奥硝唑酯二钠 125 康替唑胺片 126 注射用两性霉素B胆固醇硫酸酯复合物 127 泊沙康唑口服混悬液 128 注射用硫酸艾沙康唑 129 对氨基水杨酸肠溶颗粒 130 德拉马尼片 131 艾米替诺福韦片 132 恩替卡韦口服溶液 133 恩替卡韦颗粒 134 来迪派韦索磷布韦片 135 索磷布韦维帕他韦片 136 盐酸可洛派韦胶囊 137 索磷维伏片 138 达诺瑞韦钠片 139 盐酸拉维达韦片 140 磷酸依米他韦胶囊 141 艾考恩丙替片 142 奈韦拉平齐多拉米双夫定片 143 注射用艾博韦泰 144 比克恩丙诺片 145 艾诺韦林片 146 拉米夫定多替拉韦片 147 多拉米替片 148 阿兹夫定片 149 重组细胞因子基因衍生蛋白注射液 150 盐酸阿比多尔颗粒 151 法维拉韦片(又称:法匹拉韦片) 152 玛巴洛沙韦片 153 来特莫韦片 154 来特莫韦注射液 155 注射用紫杉醇脂质体 156 示踪用盐酸米托蒽醌注射液 157 优替德隆注射液 158 西妥昔单抗注射液 159 尼妥珠单抗注射液 160 注射用伊尼妥单抗 161 帕妥珠单抗注射液 162 信迪利单抗注射液 163 替雷利珠单抗注射液 164 特瑞普利单抗注射液 165 注射用卡瑞利珠单抗 166 奥妥珠单抗注射液 167 达雷妥尤单抗注射液 168 注射用恩美曲妥珠单抗 169 注射用维布妥昔单抗 170 甲磺酸氟马替尼片 171 甲磺酸奥希替尼片 172 甲磺酸阿美替尼片 173 盐酸安罗替尼胶囊 174 克唑替尼胶囊 175 塞瑞替尼胶囊 176 盐酸阿来替尼胶囊 177 培唑帕尼片 178 瑞戈非尼片 179 甲磺酸阿帕替尼片 180 呋喹替尼胶囊 181 马来酸吡咯替尼片 182 尼洛替尼胶囊 183 伊布替尼胶囊 184 泽布替尼胶囊 185 磷酸芦可替尼片 186 维莫非尼片 187 曲美替尼片 188 甲磺酸达拉非尼胶囊 189 甲苯磺酸多纳非尼片 190 盐酸恩沙替尼胶囊 191 甲磺酸伏美替尼片 192 达可替尼片 193 奥布替尼片 194 阿贝西利片 195 马来酸奈拉替尼片 196 索凡替尼胶囊 197 盐酸埃克替尼片 198 洛拉替尼片 199 布格替尼片 200 赛沃替尼片 201 奥雷巴替尼片 202 瑞派替尼片 203 重组人血管内皮抑制素注射液 204 西达本胺片 205 奥拉帕利片 206 甲苯磺酸尼拉帕利胶囊 207 氟唑帕利胶囊 208 帕米帕利胶囊 209 甲磺酸艾立布林注射液 210 注射用维迪西妥单抗 211 维奈克拉片 212 注射用卡非佐米 213 羟乙磺酸达尔西利片 214 醋酸戈舍瑞林缓释植入剂 215 阿帕他胺片 216 达罗他胺片 217 瑞维鲁胺片 218 注射用醋酸地加瑞克 219 硫培非格司亭注射液 220 西尼莫德片 221 盐酸芬戈莫德胶囊 222 奥法妥木单抗注射液 223 依维莫司片 224 巴瑞替尼片 225 注射用贝利尤单抗 226 注射用泰它西普 227 乌帕替尼缓释片 228 阿普米司特片 229 伊奈利珠单抗注射液 230 依那西普注射液 231 司库奇尤单抗注射液 232 乌司奴单抗注射液 233 乌司奴单抗注射液(静脉输注) 234 依奇珠单抗注射液 235 古塞奇尤单抗注射液 236 泊马度胺胶囊 237 富马酸二甲酯肠溶胶囊 238 米诺膦酸片 239 地舒单抗注射液 240 诺西那生钠注射液 241 利司扑兰口服溶液用散 242 盐酸艾司氯胺酮注射液 243 环泊酚注射液 244 利多卡因凝胶贴膏 245 普瑞巴林缓释片 246 吡仑帕奈片 247 注射用利培酮微球(II) 248 氘丁苯那嗪片 249 棕榈帕利哌酮酯注射液(3M) 250 水合氯醛灌肠剂 251 注射用甲苯磺酸瑞马唑仑 252 注射用苯磺酸瑞马唑仑 253 水合氯醛/糖浆组合包装 254 咪达唑仑口服溶液 255 咪达唑仑口颊粘膜溶液 256 盐酸曲唑酮缓释片 257 甘露特钠胶囊 258 盐酸美金刚口溶膜 259 注射用尤瑞克林 260 依达拉奉右莰醇注射用浓溶液 261 丁苯酞软胶囊 262 丁苯酞氯化钠注射液 263 氨吡啶缓释片 264 氯苯唑酸软胶囊 265 利鲁唑口服混悬液 266 苯环喹溴铵鼻喷雾剂 267 乌美溴铵维兰特罗吸入粉雾剂 268 茚达特罗格隆溴铵吸入粉雾剂用胶囊(茚达特罗格隆溴铵     吸入粉雾剂) 269 格隆溴铵福莫特罗吸入气雾剂 270 布地格福吸入气雾剂 271 氟替美维吸入粉雾剂 272 盐酸丙卡特罗粉雾剂 273 倍氯福格吸入气雾剂 274 茚达格莫吸入粉雾剂(II) 275 茚达特罗莫米松吸入粉雾剂(II) 276 茚达特罗莫米松吸入粉雾剂(III) 277 注射用奥马珠单抗 278 美泊利珠单抗注射液 279 福多司坦口服溶液 280 布林佐胺噻吗洛尔滴眼液 281 布林佐胺溴莫尼定滴眼液 282 地塞米松玻璃体内植入剂 283 康柏西普眼用注射液 284 阿柏西普眼内注射溶液 285 雷珠单抗注射液 286 环孢素滴眼液(Ⅱ) 287 复方电解质眼内冲洗液 288 肠内营养乳剂(SP) 289 环硅酸锆钠散 290 重组结核杆菌融合蛋白(EC) 291 吸入用氯醋甲胆碱 292 注射用全氟丙烷人血白蛋白微球 293 注射用全氟丁烷微球 294 牛黄清感胶囊 295 柴芩清宁胶囊 296 疏清颗粒 297 银翘清热片 298 芪黄通秘软胶囊 299 清胃止痛微丸 300 熊胆舒肝利胆胶囊 301 冬凌草滴丸 302 金银花口服液 303 热炎宁合剂 304 蓝芩口服液 305 清肺排毒颗粒 306 痰热清胶囊 307 鸡骨草胶囊 308 利胆止痛胶囊 309 五味苦参肠溶胶囊 310 小儿荆杏止咳颗粒 311 连花清咳片 312 金花清感颗粒 313 化湿败毒颗粒 314 宣肺败毒颗粒 315 麻芩消咳颗粒 316 射麻口服液 317 小儿牛黄清心散 318 缓痛止泻软胶囊 319 甘海胃康胶囊 320 百令胶囊 321 参乌益肾片 322 芪黄颗粒 323 桑枝总生物碱片 324 通脉降糖胶囊 325 参龙宁心胶囊 326 芪蛭益肾胶囊 327 注射用益气复脉(冻干) 328 益肾养心安神片 329 八味芪龙颗粒 330 杜蛭丸 331 脑心安胶囊 332 芪丹通络颗粒 333 芪芎通络胶囊 334 心脉隆注射液 335 蒺藜皂苷胶囊 336 丹红注射液 337 蛭蛇通络胶囊 338 西红花总苷片 339 注射用丹参多酚酸 340 注射用丹参多酚酸盐 341 血必净注射液 342 银杏内酯注射液 343 银杏二萜内酯葡胺注射液 344 丹灯通脑软胶囊 345 解郁除烦胶囊 346 七蕊胃舒胶囊 347 芍麻止痉颗粒 348 川芎清脑颗粒 349 降脂通络软胶囊 350 复方黄黛片 351 食道平散 352 康莱特注射液 353 康艾注射液 354 参一胶囊 355 注射用黄芪多糖 356 五虎口服液 357 筋骨止痛凝胶 358 玄七健骨片 359 关黄母颗粒 360 坤心宁颗粒 361 安儿宁颗粒 362 红花如意丸 363 如意珍宝片 364 注射用福沙匹坦双葡甲胺 365 硫酸镁钠钾口服用浓溶液 366 复合磷酸氢钾注射液 367 复方氨基酸(15AA-II)/葡萄糖(10%)电解质注射液 368 碳酸氢钠林格注射液 369 氨基酸(15)腹膜透析液 370 托伐普坦片 371 注射用多黏菌素E甲磺酸钠 372 泊沙康唑肠溶片 373 泊沙康唑注射液 374 哌柏西利胶囊 375 枸橼酸托法替布缓释片 376 普瑞巴林口服溶液 377 拉考沙胺注射液 378 奥氮平口溶膜 379 盐酸安非他酮缓释片(II) 380 舒更葡糖钠注射液 381 林普利塞片 382 枸橼酸钠血滤置换液 383 琥珀酸瑞波西利片 384 维立西呱片 385 多格列艾汀片 386 黄蜀葵花总黄酮口腔贴片 387 艾加莫德α注射液 388 芪胶调经颗粒 389 芦比前列酮软胶囊 390 安奈拉唑钠肠溶片 391 多种微量元素注射液(Ⅲ) 392 艾诺米替片 393 泽贝妥单抗注射液 394 氢溴酸氘瑞米德韦片 395 塞利尼索片 396 瑞帕妥单抗注射液 397 虎贞清风胶囊 398 去氨加压素口服溶液 399 注射用头孢噻肟钠他唑巴坦钠 400 恩那度司他片 401 参葛补肾胶囊 402 注射用右兰索拉唑 403 西格列汀二甲双胍缓释片(Ⅱ) 404 淫羊藿素软胶囊 405 美沙拉秦肠溶缓释胶囊 406 连榆烧伤膏 407 盐酸可乐定缓释片 408 盐酸奈康唑乳膏 409 注射用多种维生素(13) 410 奥磷布韦片 411 佩索利单抗注射液 412 甲磺酸贝福替尼胶囊 413 盐酸替洛利生片 414 氨磺必利口服溶液 415 硫酸氢司美替尼胶囊 416 磷酸瑞格列汀片 417 布比卡因脂质体注射液 418 盐酸右美托咪定鼻喷雾剂 419 盐酸奥扎莫德胶囊 420 度维利塞胶囊 421 妥布霉素吸入溶液 422 盐酸凯普拉生片 423 注射用头孢地嗪钠/5%葡萄糖注射液 424 盐酸米托蒽醌脂质体注射液 425 八氟丙烷脂质微球注射液 426 琥珀酸地文拉法辛缓释片 427 伏罗尼布片 428 酒石酸艾格司他胶囊 429 注射用头孢地嗪钠/氯化钠注射液 430 盐酸奥洛他定颗粒 431 盐酸溴己新口服溶液 432 贝米肝素钠注射液 433 注射用头孢西丁钠/氯化钠注射液 434 达格列净二甲双胍缓释片(I) 435 甘精胰岛素利司那肽注射液(Ⅰ) 436 甘精胰岛素利司那肽注射液(Ⅱ) 437 苓桂术甘颗粒 438 散寒化湿颗粒 439 地西泮鼻喷雾剂 440 替瑞奇珠单抗注射液 441 复方聚乙二醇(3350)电解质散 442 阿可替尼胶囊 443 磷酸索立德吉胶囊 444 依库珠单抗注射液 445 注射用奥马珠单抗α 446 注射用醋酸曲普瑞林微球 447 甲氧聚二醇重组人促红素注射液 448 盐酸利多卡因眼用凝胶 449 曲妥珠单抗注射液(皮下注射) 450 恩曲替尼胶囊 451 艾贝格司亭α注射液 452 盐酸氟西汀口服溶液 453 蔗糖羟基氧化铁咀嚼片 454 氯化钾口服溶液 455 广金钱草总黄酮胶囊 456 西罗莫司凝胶 457 注射用司妥昔单抗 458 富马酸奥赛利定注射液 459 治疗用碘[131I]化钠胶囊 460 芦曲泊帕片 461 萨特利珠单抗注射液 462 右酮洛芬氨丁三醇注射液 463 注射用戈舍瑞林微球 464 拓培非格司亭注射液 465 培莫沙肽注射液 466 ω-3甘油三酯(2%)中/长链脂肪乳/氨基酸(16)/葡萄糖(36%)     注射液 467 氟轻松玻璃体内植入剂 468 盐酸丙卡特罗吸入溶液 469 谷美替尼片 470 阿伐替尼片 471 琥珀酰明胶电解质醋酸钠注射液 472 酮洛芬凝胶贴膏 473 孟鲁司特钠口溶膜 474 奥马珠单抗注射液 475 硫酸艾沙康唑胶囊 476 丁甘交联玻璃酸钠注射液 477 阿立哌唑口溶膜 478 伊鲁阿克片 479 中长链脂肪乳/氨基酸(16)/葡萄糖(30%)注射液 480 来瑞特韦片 481 羧基麦芽糖铁注射液 482 复方氨基酸(16AA)/葡萄糖(12.6%)电解质注射液 483 先诺特韦片/利托那韦片组合包装 484 甲苯磺酸奥马环素片 485 阿瑞匹坦注射液 486 曲氟尿苷替匹嘧啶片 487 复方电解质醋酸钠葡萄糖注射液 488 氨己烯酸口服溶液用散 489 骨化三醇口服溶液 490 盐酸右美托咪定氯化钠注射液 491 西格列汀二甲双胍缓释片 492 注射用头孢曲松钠/氯化钠注射液 493 吸入用盐酸氨溴索溶液 494 氮䓬斯汀氟替卡松鼻喷雾剂 495 尼替西农胶囊 496 草酸艾司西酞普兰口服溶液 497 氢溴酸替格列汀片 498 山梨醇甘露醇冲洗剂 499 丁苯那嗪片 500 磷酸特地唑胺片 501 注射用头孢他啶阿维巴坦钠 502 依沃西单抗注射液 503 恩朗苏拜单抗注射液 504 卡度尼利单抗注射液 505 帕妥珠曲妥珠单抗注射液（皮下注射） 506 注射用德曲妥珠单抗 507 西妥昔单抗β注射液 508 盐酸特泊替尼片 509 戈利昔替尼胶囊 510 注射用埃普奈明 511 甲磺酸瑞厄替尼片 512 甲磺酸瑞齐替尼胶囊 513 瑞普替尼胶囊 514 舒沃替尼片 515 枸橼酸依奉阿克胶囊 516 富马酸安奈克替尼胶囊 517 盐酸卡马替尼片 518 注射用盐酸曲拉西利 519 注射用维泊妥珠单抗 520 注射用紫杉醇聚合物胶束 521 硫酸拉罗替尼胶囊 522 硫酸拉罗替尼口服溶液 523 赛帕利单抗注射液 524 法瑞西单抗注射液 525 磷/碳酸氢钠血滤置换液 526 阿利沙坦酯氨氯地平片 527 依普利酮片 528 瑞舒伐他汀依折麦布片（I） 529 托莱西单抗注射液 530 玛伐凯泰胶囊 531 注射用罗普司亭N01 532 甲磺酸贝舒地尔片 533 重组人凝血酶 534 苯甲酸福格列汀片 535 考格列汀片 536 恒格列净二甲双胍缓释片（I） 537 恒格列净二甲双胍缓释片（II） 538 盐酸二甲双胍缓释片（Ⅳ） 539 脯氨酸加格列净片 540 依柯胰岛素注射液 541 布立西坦片 542 地达西尼胶囊 543 盐酸纳呋拉啡口崩片 544 布地奈德肠溶胶囊 545 苯磺酸克利加巴林胶囊 546 苯磺酸美洛加巴林片 547 富马酸泰吉利定注射液 548 盐酸氢吗啡酮缓释片 549 水合氯醛糖浆 550 注射用磷丙泊酚二钠 551 注射用头孢比罗酯钠 552 注射用头孢他啶阿维巴坦钠/氯化钠注射液 553 阿泰特韦片/利托那韦片组合包装 554 玛巴洛沙韦干混悬剂 555 奥特康唑胶囊 556 马立巴韦片 557 注射用头孢哌酮钠舒巴坦钠/氯化钠注射液 558 氟哌啶醇口服溶液 559 盐酸托鲁地文拉法辛缓释片 560 注射用阿立哌唑 561 棕榈帕利哌酮酯注射液（6M） 562 纳鲁索拜单抗注射液 563 妥拉美替尼胶囊 564 伯瑞替尼肠溶胶囊 565 达雷妥尤单抗注射液（皮下注射） 566 贝前列素钠缓释片 567 依折麦布阿托伐他汀钙片（Ⅱ） 568 地拉罗司颗粒 569 盐酸伊普可泮胶囊 570 司替戊醇干混悬剂 571 氯巴占片 572 黄体酮注射液（Ⅱ） 573 氘可来昔替尼片 574 盐酸非索非那定干混悬剂 575 济川煎颗粒 576 儿茶上清丸 577 九味止咳口服液 578 一贯煎颗粒 579 益气通窍丸 580 秦威颗粒 581 通络明目胶囊 582 温经汤颗粒 583 小儿豉翘清热糖浆 584 小儿紫贝宣肺糖浆 585 枳实总黄酮片 586 非诺贝特酸胆碱缓释胶囊 587 二甲双胍恩格列净片 （Ⅵ） 588 二甲双胍恩格列净片（Ⅲ） 589 他克莫司颗粒 590 氯苯唑酸葡胺软胶囊 591 全氟己基辛烷滴眼液 592 鱼油(3%)橄榄油中/长链脂肪乳/氨基酸(16)/葡萄糖(13%)注射液 593 雌二醇地屈孕酮片 594 斯泰度塔单抗注射液 595 安瑞克芬注射液 596 布西珠单抗注射液 597 替妥尤单抗N01注射液 598 锝[99mTc]替曲膦注射液 599 玛舒拉沙韦片 600 昂拉地韦片 601 普托马尼片 602 甲磺酸普雷福韦片 603 恩曲利匹丙诺片 604 醋酸来法莫林注射用浓溶液 605 醋酸来法莫林片 606 注射用亚胺培南西司他丁钠/氯化钠注射液 607 注射用美罗培南/氯化钠注射液 608 盐酸万古霉素胶囊 609 注射用氨曲南阿维巴坦钠 610 盐酸替那帕诺片 611 依伏卡塞片 612 戊二酸利那拉生酯胶囊 613 怡培生长激素注射液 614 瑞格列汀二甲双胍片(Ⅰ) 615 瑞格列汀二甲双胍片(Ⅱ) 616 依苏帕格鲁肽α注射液 617 金培生长激素注射液 618 多替诺雷片 619 替尔泊肽注射液 620 棕榈酸帕利哌酮注射液(Ⅱ) 621 奥氮平氟西汀胶囊 622 注射用阿立哌唑微球 623 氨磺必利口崩片 624 舒马普坦萘普生钠片 625 注射用替奈普酶 626 注射用阿格司亭α 627 本瑞利珠单抗注射液 628 阿地溴铵吸入粉雾剂 629 盐酸胍法辛缓释片 630 盐酸右哌甲酯缓释胶囊 631 奥瑞利珠单抗注射液 632 磷苯妥英钠注射用浓溶液 633 沙库巴曲阿利沙坦钙片 634 英克司兰钠注射液 635 阿利沙坦酯吲达帕胺缓释片 636 伊努西单抗注射液 637 注射用瑞卡西单抗 638 昂戈瑞西单抗注射液 639 盐酸拉贝洛尔氯化钠注射液 640 夫那奇珠单抗注射液 641 赛立奇单抗注射液 642 依若奇单抗注射液 643 硫酸艾玛昔替尼片 644 司普奇拜单抗注射液 645 利生奇珠单抗注射液 646 古塞奇尤单抗注射液(静脉输注) 647 利生奇珠单抗注射液(皮下注射) 648 盐酸吉卡昔替尼片 649 艾伏尼布片 650 马来酸阿可替尼片 651 匹妥布替尼片 652 注射用磷罗拉匹坦帕洛诺司琼 653 注射用培妥罗凝血素α 654 去铁酮片 655 艾沙妥昔单抗注射液 656 注射用重组人凝血因子Ⅶa N01 657 格菲妥单抗注射液 658 利厄替尼片 659 盐酸佐利替尼片 660 塞纳帕利胶囊 661 普拉替尼胶囊 662 塞普替尼胶囊 663 己二酸他雷替尼胶囊 664 尼拉帕利阿比特龙片 665 菲诺利单抗注射液 666 塔戈利单抗注射液 667 艾帕洛利托沃瑞利单抗注射液 668 注射用苏维西塔单抗 669 派安普利单抗注射液 670 注射用芦康沙妥珠单抗 671 吡洛西利片 672 注射用瑞康曲妥珠单抗 673 枸橼酸伏维西利胶囊 674 恩替司他片 675 盐酸来罗西利片 676 醋酸甲地孕酮口服混悬液 677 紫杉醇口服溶液 678 盐酸伊立替康脂质体注射液(Ⅱ) 679 西妥昔单抗N01注射液 680 醋酸阿比特龙片(Ⅱ) 681 氘恩扎鲁胺软胶囊 682 氟泽雷塞片 683 卡匹色替片 684 伊那利塞片 685 枸橼酸戈来雷塞片 686 苹果酸法米替尼胶囊 687 格索雷塞片 688 芦沃美替尼片 689 复方比那甫西颗粒 690 芪防鼻通片 691 温阳解毒颗粒 692 玉女煎颗粒 693 参郁宁神片 694 养血祛风止痛颗粒 695 益气清肺颗粒 696 羟考酮纳洛酮缓释片 697 注射用盐酸头孢吡肟/氯化钠注射液 698 呋塞米口服溶液 699 醋酸氟氢可的松片 700 熊去氧胆酸口服混悬液 701 吡仑帕奈口服混悬液 702 盐酸伊立替康脂质体注射液 据上海药事所说明： 1、调出目录的谈判药品（贝那鲁肽注射液、达诺瑞韦钠片、盐酸拉维达韦片、阿利西尤单抗注射液、度维利塞胶囊、八氟丙烷脂质微球注射液、甘露特钠胶囊、林普利塞片）6 个月过渡期结束后调出“双通道”药品范围； 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*本资料仅供医疗卫生专业人士参考，请勿向非医疗卫生专业人士发放 截至01月01日15点59分，近期共有 293 本期刊发布了 930 篇文章，其中糖尿病相关的文章共 312 篇，覆盖 28 个领域的内容。中国专家参与发表的文章有 70 篇。今日，影响因子最高的文章刊登在 iMeta (IF: 33.200) 期刊上。 今日头条 Headlines 01 iMeta IF: 33.200 单细胞空间转录组学揭示Abelmoschus manihot (L.) Medic治疗糖尿病肾病的潜在分子机制 Wu, Chenhua, Tang, Haitao, Yu, Yihong, Song, Yuhui, Ge, Haitao, Shen, Yiming, etc. 糖尿病肾病（DKD）作为糖尿病最常见且严重的微血管并发症之一，是全球终末期肾病的主要原因，给患者和社会带来沉重负担。尽管现有治疗策略不断优化，但探索更有效、多靶点的治疗方案仍是医学研究的重要方向。近年来，传统中药在DKD治疗中显示出独特优势，其中源自中药黄蜀葵花（Abelmoschus manihot (L.) Medic）的制剂——黄葵胶囊（HKC）在临床应用中表现出良好的疗效。 近日，一项发表于 iMeta 期刊的研究，结合前沿的单细胞空间转录组学技术，深入揭示了黄蜀葵花核心活性成分——总黄酮（TFA）治疗DKD的潜在分子机制。该研究由 Chenhua Wu、Haitao Tang、Harvest F. Gu 等学者共同完成。 研究团队以经典的2型糖尿病及DKD动物模型——db/db小鼠为研究对象，将其分为正常对照组、DKD模型组、TFA治疗组以及阳性对照药厄贝沙坦（IRB）治疗组。经过为期四周的干预，研究人员确认，TFA单药治疗能够显著降低db/db小鼠的尿蛋白水平，并有效改善肾脏组织学上的病理损伤，包括肾小球硬化、基底膜增厚和炎性细胞浸润，其疗效与TFA联合IRB或IRB单药治疗相当。 为了在空间维度上解析TFA的作用机制，研究采用了高分辨率的空间转录组学技术，成功绘制了db/db小鼠肾脏在疾病状态及药物干预下的单细胞水平空间基因表达图谱。该图谱精准识别并定位了肾脏中包括近端小管细胞、髓袢细胞、集合管主细胞、足细胞、内皮细胞、系膜细胞以及巨噬细胞、T细胞等在内的16种主要细胞类型。 通过对空间转录组数据的深度挖掘，研究人员构建了肾脏细胞的转录调控网络。他们发现，在DKD发生发展过程中，一组关键的转录调节因子，如Stat1、Jun、Junb等，在多种肾脏实质细胞和免疫细胞中的活性显著增强。而无论是TFA还是IRB治疗，均能有效抑制这些调节因子的异常活性。 进一步追溯其上游，研究发现，这些关键调节因子的活性受到特定细胞表面受体的调控。例如，整合素受体Itgb5的表达在DKD模型的巨噬细胞和集合管主细胞中升高，而TFA和IRB治疗可使其表达下调。分子对接模拟分析提示，TFA中的活性成分槲皮素可能与Itgb5结合，进而抑制其下游的Stat1信号通路。同时，TFA中的多种黄酮类成分可能共同作用于转化生长因子-β受体Tgfbr1，抑制其介导的促纤维化信号。 该研究从单细胞空间分辨率的视角，系统描绘了TFA干预DKD的分子图谱，揭示了其通过调控Itgb5-Stat1、Tgfbr1等关键受体-调节因子轴，减轻肾脏免疫炎症反应和纤维化进程，从而发挥肾脏保护作用的潜在机制。这些发现为阐明中药黄蜀葵花治疗糖尿病肾病的现代科学内涵提供了重要的实验依据，也为未来开发多靶点抗DKD药物提供了新的思路和靶点。 本文由 天纳乾坤 编辑 扫描二维码查看源文 iMeta | Volume 4, Issue 6 10.1002/imt2.70099 02 Nature methods IF: 32.100 cellSTAAR：整合单细胞测序功能数据以增强非编码区罕见变异关联检验效力 Van Buren, Eric, Zhang, Yi, Li, Xihao, Selvaraj, Margaret Sunitha, Li, Zilin, Zhou, Hufeng, etc. 近日，一项发表于 Nature methods 的研究介绍了一种名为cellSTAAR的创新分析方法，该方法旨在破解非编码区罕见遗传变异影响复杂性状的难题。该研究由 Eric Van Buren、Yi Zhang、Xihao Li 等来自多所研究机构的众多学者共同完成。 理解罕见遗传变异如何影响如血脂水平等复杂性状，是现代遗传学面临的主要挑战之一，尤其当这些变异位于基因组的非编码区域时。这些位于候选顺式调控元件内的变异，其效应常常因细胞类型而异，这为解读工作带来了巨大困难。为此，研究者开发了cellSTAAR。 cellSTAAR的核心在于数据整合与策略创新。该方法将大规模人群的全基因组测序数据，与能够揭示染色质可及性在不同细胞类型中差异的单细胞ATAC测序数据相结合。通过这种整合，cellSTAAR能够构建出细胞类型特异性的功能注释和调控元件图谱。更重要的是，为了应对cCREs（候选顺式调控元件）与靶基因之间关联的不确定性，该方法采用了一套综合性的策略来链接cCREs与其可能调控的基因，从而更全面地捕捉潜在的基因调控网络。 为了验证cellSTAAR的效力，研究团队将其应用于两个大型人群队列。首先，他们在Trans-Omics for Precision Medicine联盟约60,000人的数据中进行了分析。随后，为了确保结果的可靠性，他们在规模更大的UK Biobank约190,000人的数据中进行了独立验证。研究的焦点集中在四种重要的血脂性状上。 分析结果表明，与不整合细胞类型特异性信息的方法相比，cellSTAAR显著提升了对非编码区罕见变异与血脂性状关联的检测能力。更重要的是，该方法发现的关联信号具有更强的生物学可解释性，能够更清晰地指向特定细胞类型中可能受影响的调控通路。这些发现证明，在基于全基因组测序的罕见变异关联研究中，采用这种细胞类型感知的策略，可以有效推动新发现并加深我们对复杂性状遗传基础的理解。 本文由 天纳乾坤 编辑 扫描二维码查看源文 Nature methods | Ahead of Print. 10.1038/s41592-025-02919-5 03 Gut : IF: 25.800 代谢功能障碍相关脂肪性肝炎的联合疗法：挑战与机遇 Zhou, Xiao-Dong, Fan, Qiong-Yue, Byrne, Christopher D, Targher, Giovanni, Muthiah, Mark D, Huang, Daniel Q, etc. 近日，一篇发表于《Gut》期刊的综述文章《Combination therapies for metabolic dysfunction-associated steatohepatitis: challenges and opportunities》深入探讨了针对代谢功能障碍相关脂肪性肝炎（MASH）的联合治疗策略。MASH作为一种与肥胖、胰岛素抵抗等心脏代谢共病密切相关的复杂肝病，其治疗正面临从单药到多药联合的范式转变。 该文章指出，由于MASH发病机制涉及多条通路，传统的单药治疗往往只能带来肝脏纤维化和全身代谢参数的部分改善，疗效有限。这促使研究人员和临床医生将目光投向了能够同时作用于多个互补靶点的联合疗法。文章强调，这种多靶点策略旨在通过协同作用，达到比任何单一药物更优的治疗效果。 具体而言，联合疗法可以从不同维度设计。一类是专注于肝脏本身的“肝脏导向”组合，例如将甲状腺激素受体-β（THR-β）激动剂与乙酰辅酶A羧化酶（ACC）抑制剂或过氧化物酶体增殖物激活受体（PPAR）激动剂联用，其主要目标是更有效地改善肝脏脂肪变性、炎症和纤维化等核心组织学病变。 另一类策略则将改善全身代谢状态与针对肝脏的特异性作用结合起来。例如，胰高血糖素样肽-1（GLP-1）受体激动剂在有效降低体重、改善血糖的同时，若与成纤维细胞生长因子-21（FGF-21）类似物或THR-β激动剂联合，有望实现对肝脏和全身代谢指标的双重优化，为患者带来更全面的健康获益。 值得注意的是，联合用药还可能解决单药治疗中的安全性瓶颈。文章提到，一些经过深思熟虑的药物配对能够利用其机制的互补性来抵消彼此潜在的副作用。例如，二酰基甘油O-酰基转移酶2（DGAT2）抑制剂与ACC抑制剂的组合，或者GLP-1/胰高血糖素双重受体激动剂，其设计初衷之一就是提高整体的安全性和患者的耐受性。 这篇综述系统地整合了该领域的最新知识，不仅阐述了各种联合方案的生物学原理，也审视了正在涌现的临床证据。作者团队由Zhou Xiao-Dong、Fan Qiong-Yue、Byrne Christopher D、Targher Giovanni、Muthiah Mark D、Huang Daniel Q、Chen Qin-Fen、Noureddin Mazen、Li Wenhao、Ratziu Vlad、Loomba Rohit、Francque Sven M、Sanyal Arun J和Zheng Ming-Hua等多位国际肝病与代谢领域专家组成。 文章最后指出，合理设计并实施联合疗法是未来MASH管理的重要方向。其最终目标是超越单药治疗的局限，为患者提供在肝脏病理逆转和全身代谢健康改善方面更强大、更持久的解决方案。这为临床医生和研究者提供了一个优化MASH个体化治疗的综合性框架。 本文由 天纳乾坤 编辑 扫描二维码查看源文 Gut : | Ahead of Print. 10.1136/gutjnl-2025-337431 中国发表（70） China Eur J Med Res IF: 03.400Ahead of Print.No.01Sex-specific differences in the prognostic value of METS-IR for long-term outcomes in patients with MASLD and advanced liver fibrosis: a nationwide studyMETS-IR对MASLD合并晚期肝纤维化患者长期预后的预测价值存在性别差异：一项全国性研究DOI: 10.1186/s40001-025-03783-x Comp Biochem Physiol Part D Genomics Proteomics IF: 02.400Ahead of Print.No.02Comparative transcriptomics identifies key genes and pathways underlying the early skin coloration in leopard coral grouper (Plectropomus leopardus)比较转录组学揭示豹纹珊瑚鳟早期皮肤着色的关键基因与通路DOI: 10.1016/j.cbd.2025.101736 Eur J Med Res IF: 03.400Ahead of Print.No.03Triglyceride glucose index and atherogenic index of plasma predict rapid kidney function decline in cardiovascular-kidney-metabolic syndrome: the first longitudinal evidence from CHARLS甘油三酯-葡萄糖指数与血浆致动脉粥样硬化指数预测心血管-肾脏-代谢综合征患者的肾功能快速下降：来自CHARLS的一项纵向研究证据DOI: 10.1186/s40001-025-03751-5 BMJ open IF: 02.300Volume 15, Issue 12No.04Association between the cumulative average triglyceride glucose-body mass index and glycaemic state transitions in adults with pre-diabetes: evidence from the CHARLS cohort累积平均甘油三酯葡萄糖-体质量指数与成人糖尿病前期患者血糖状态转变的关联：来自CHARLS队列的证据DOI: 10.1136/bmjopen-2025-099014 BMC endocrine disorders IF: 03.300Ahead of Print.No.05New sights of tumor-specific growth factor (TSGF) in T2DM patients with coronary artery disease2型糖尿病合并冠状动脉疾病患者中肿瘤特异性生长因子（TSGF）的新见解DOI: 10.1186/s12902-025-02152-3 Journal of Advanced Research IF: 13.000Ahead of Print.No.06Plasma apolipoprotein E protein attenuates pulmonary fibrosis through LRP1 and PLAU dual receptor-mediated TGF-β/Smad inhibition血浆载脂蛋白E蛋白通过LRP1和PLAU双受体介导的TGF-β/Smad抑制减轻肺纤维化DOI: 10.1016/j.jare.2025.12.045 Journal of controlled release IF: 11.500Ahead of Print.No.07Local cochlear delivery of berberine chloride hydrate via an injectable photo-crosslinked hydrogel for treating diabetes- induced hearing loss通过可注射光交联水凝胶局部递送盐酸小檗碱治疗糖尿病性听力损失DOI: 10.1016/j.jconrel.2025.114582 Diabetes & metabolic syndrome IF: 03.400Ahead of Print.No.08Efficacy and safety of finerenone in the treatment of primary aldosteronism: A prospective clinical study非奈利酮治疗原发性醛固酮增多症的有效性与安全性：一项前瞻性临床研究DOI: 10.1016/j.dsx.2025.103369 Colloids Surf B Biointerfaces IF: 05.600Ahead of Print.No.09Cascade ROS-modulating Au/Cu nanozyme hydrogel with nitric oxide release ability for accelerated diabetic foot ulcer healing兼具一氧化氮释放能力的级联ROS调节型金/铜纳米酶水凝胶加速糖尿病足溃疡愈合DOI: 10.1016/j.colsurfb.2025.115403 Colloids Surf B Biointerfaces IF: 05.600Ahead of Print.No.10Baicalein-manganese nanoparticles for antioxidant and osteogenic therapy of bone injury黄芩素-锰纳米颗粒用于骨损伤的抗氧化及成骨治疗DOI: 10.1016/j.colsurfb.2025.115400 Ophthalmology retina IF: 05.700Ahead of Print.No.11Timing of Preoperative Anti-VEGF for Vitrectomy in Proliferative Diabetic Retinopathy: A Competing-Risks Analysis of a Large Cohort增生性糖尿病视网膜病变玻璃体切除术术前抗VEGF用药时机：基于大样本队列的竞争风险分析DOI: 10.1016/j.oret.2025.12.019 Experimental Eye Research IF: 02.700Ahead of Print.No.12Age-related Alterations in Retinal Structure and Blood Perfusion in TIPE2 Gene-Knockout MiceTIPE2基因敲除小鼠视网膜结构与血液灌注的年龄相关改变DOI: 10.1016/j.exer.2025.110834 Gut : IF: 25.800Ahead of Print.No.13Combination therapies for metabolic dysfunction-associated steatohepatitis: challenges and opportunities代谢功能障碍相关脂肪性肝炎的联合疗法：挑战与机遇DOI: 10.1136/gutjnl-2025-337431 Carbohydrate polymers IF: 12.500Volume 375, Issue No.14Structural characterization and lipid-modulating effects of an inulin-type fructan from Bacillus amyloliquefaciens D189: Unraveling the microbiota-gut-liver axis解淀粉芽孢杆菌D189来源的菊粉型果聚糖的结构表征与脂质调节作用：揭示微生物-肠-肝轴机制DOI: 10.1016/j.carbpol.2025.124809 Carbohydrate polymers IF: 12.500Volume 375, Issue No.15Chitosan/selenium nanoparticles Pickering emulsion prolong quercetin retention time to ameliorates cognitive disorder: Focus on restoring the metabolic disorder and gut microbiota壳聚糖/硒纳米颗粒Pickering乳液通过延长槲皮素保留时间改善认知障碍：聚焦于恢复代谢紊乱与肠道菌群DOI: 10.1016/j.carbpol.2025.124804 Carbohydrate polymers IF: 12.500Volume 375, Issue No.16Chitosan and chito-oligosaccharides as multifunctional therapeutics for metabolic dysfunction-associated steatotic liver disease (MASLD)壳聚糖与壳寡糖作为代谢相关脂肪性肝病的多功能疗法DOI: 10.1016/j.carbpol.2025.124737 Journal of affective disorders IF: 04.900Ahead of Print.No.17Sex differences in prevalence of subclinical hypothyroidism and its clinical correlates in overweight or obese, first-episode drug-naïve Chinese patients with major depressive disorder中国超重或肥胖、首次发作未用药重性抑郁障碍患者中亚临床甲状腺功能减退症的患病率及临床相关因素的性别差异DOI: 10.1016/j.jad.2025.121068 Annals of medicine IF: 04.300Volume 58, Issue 1No.18Zinc status following different bariatric procedures: systematic review and meta-analysis不同减重手术后锌水平的系统评价与Meta分析DOI: 10.1080/07853890.2025.2608532 Nutrition IF: 03.000Ahead of Print.No.19Estimating resting metabolic rate in older Chinese adults:A community-based study integrating dietary predictors老年中国人群静息代谢率估算：一项整合膳食预测因子的社区研究DOI: 10.1016/j.nut.2025.113054 JMIR aging IF: 04.800Volume 8, Issue No.20Association of Insulin Resistance, Sarcopenia, and Risk of Cardiovascular Disease: Findings From the China Health and Retirement Longitudinal Study胰岛素抵抗、肌肉减少症与心血管疾病风险的关联：基于中国健康与养老追踪调查的发现DOI: 10.2196/80115 The Journal of cell biology IF: 06.400Volume 225, Issue 2No.21In vivo mapping of peroxisome dynamics and pexophagy using PO-TRG and CA-PO-TRG reporter mice使用PO-TRG及CA-PO-TRG报告小鼠进行体内过氧化物酶体动态及过氧化物酶体自噬（Pexophagy）绘图DOI: 10.1083/jcb.202503169 Biomaterials advances IF: 06.000Ahead of Print.No.22Design, fabrication, and evaluation of antimicrobial sponge-hydrogel bilayer microneedles: An integrated system for transdermal insulin delivery and glucose sensing抗菌海绵-水凝胶双层微针的设计、制备与评估：一个用于透皮胰岛素输送与葡萄糖传感的集成系统DOI: 10.1016/j.bioadv.2025.214693 Medical physics IF: 03.200Volume 53, Issue 1No.23Weakly supervised object detection network for diabetic retinopathy弱监督目标检测网络用于糖尿病视网膜病变检测DOI: 10.1002/mp.70264 Frontiers in nutrition IF: 05.100Volume 12, Issue No.24Correction: Diagnostic efficacy of remnant cholesterol inflammatory index in diabetic kidney disease: machine learning approaches更正：残留胆固醇炎症指数在糖尿病肾病中的诊断有效性：机器学习方法DOI: 10.3389/fnut.2025.1755030 iMeta IF: 33.200Volume 4, Issue 6No.25Single-cell spatial transcriptomics reveals potential molecular mechanisms of Abelmoschus manihot (L.) medic in treating diabetic kidney disease单细胞空间转录组学揭示Abelmoschus manihot (L.) Medic治疗糖尿病肾病的潜在分子机制DOI: 10.1002/imt2.70099 Chinese Medical Journal IF: 07.300Ahead of Print.No.26Association of cardiovascular-kidney-metabolic syndrome stages with mortality: A nationwide, population-based, prospective cohort study心血管-肾脏-代谢综合征分期与死亡率的关联：一项全国性、基于人群的前瞻性队列研究DOI: 10.1097/CM9.0000000000003914 IDCases IF: 01.000Volume 42, Issue No.27Silent pulmonary tuberculosis in patients with poorly controlled diabetes mellitus: Pathogenesis, clinical implications, and diagnostic challenges血糖控制不佳糖尿病患者中的隐匿性肺结核：发病机制、临床意义与诊断挑战DOI: 10.1016/j.idcr.2025.e02357 Frontiers in oncology IF: 03.300Volume 15, Issue No.28Poor nutritional status based on controlling nutritional status score and nutritional risk index may be related to the occurrence of complications after laparoscopic treatment in patients with gastrointestinal tumors aged no more than 60 years基于CONUT评分和NRI的营养不良状态可能与60岁及以下的胃肠道肿瘤患者腹腔镜治疗后并发症的发生有关DOI: 10.3389/fonc.2025.1723703 Frontiers in medicine IF: 03.000Volume 12, Issue No.29Analysis of prognostic prediction and nursing intervention value in PD patients based on nomogram model基于列线图模型对腹膜透析患者预后预测及护理干预价值的分析DOI: 10.3389/fmed.2025.1645631 FCVM IF: 02.900Volume 12, Issue No.30SGLT2 inhibitor short-term efficacy and SYNTAX score association in coronary heart disease retinopathy: a propensity score matching studySGLT2抑制剂短期有效性及SYNTAX评分与冠心病视网膜病变的关联：一项倾向性评分匹配研究DOI: 10.3389/fcvm.2025.1651251 Frontiers in immunology IF: 05.900Volume 16, Issue No.31The multifaceted roles and diagnostic-therapeutic potential of LINC01410 in malignant tumors and non-malignant disordersLINC01410在恶性肿瘤及非恶性疾病中的多维角色与诊疗潜力DOI: 10.3389/fimmu.2025.1588816 J Multidiscip Healthc IF: 02.400Volume 18, Issue No.32Impact of Medical-Prevention Integration on Resource Utilization Efficiency in Chronic Disease Management Among Older Adults: Ethical and Economic Perspectives医防融合模式对老年人慢性病管理资源利用效率的影响：伦理与经济视角DOI: 10.2147/JMDH.S564477 Diabetic medicine IF: 03.400Ahead of Print.No.33The exosome-PI3K/Akt-autophagy axis in diabetic vascular complications: Mechanisms and implications糖尿病血管并发症中的外泌体-PI3K/Akt-自噬轴：机制与意义DOI: 10.1111/dme.70196 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.34The Impacts of Major Chronic Diseases on Changes in Healthy Life Expectancy among Older Adults in China from 2011 to 20202011-2020年中国老年人主要慢性病对健康预期寿命变化的影响DOI: 10.3967/bes2025.064 Oral diseases IF: 02.900Ahead of Print.No.35Exposure to Famine in Early Childhood Increases the Odds of Edentulism in Adulthood: Results From the China Health and Retirement Longitudinal Study童年早期经历饥荒增加成年后无牙症风险：基于中国健康与养老追踪调查的结果DOI: 10.1111/odi.70177 CCI IF: 01.900Ahead of Print.No.36The Radial Artery Occlusion Paradox: The Larger-Bore Sheath via the Thinner Distal Radial Artery for Coronary Interventional Procedures桡动脉闭塞悖论：经远端桡动脉应用大鞘管行冠状动脉介入治疗DOI: 10.1002/ccd.70456 Microorganisms IF: 04.200Volume 13, Issue 12No.37Alterations in Gut Microbial Co-Abundance Networks in Metabolic Syndrome: A Population-Based Cross-Sectional Study代谢综合征患者肠道微生物共丰度网络的改变：一项基于人群的横断面研究DOI: 10.3390/microorganisms13122759 Ann Agric Environ Med IF: 01.200Volume 32, Issue 4No.38Association between obesity and non-alcoholic fatty liver disease (NAFLD) in adults aged 18 years and above - data from NHANES 2017-201818岁及以上成人中肥胖与非酒精性脂肪性肝病的关联——基于NHANES 2017-2018数据DOI: 10.26444/aaem/210489 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.39Anthropometric Obesity Measures and Diabetes Progression from Prediabetes in Older Adults: A Comparison of American Diabetes Association and World Health Organization Criteria老年人体质指数及腰围测量与糖尿病前期向糖尿病进展的关系：美国糖尿病协会与世界卫生组织诊断标准的比较DOI: 10.3967/bes2025.090 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.40Association of Frailty with Mortality and Incident Cardiovascular Disease: The Role of Metabolic Status衰弱与死亡和心血管疾病发病风险的关联：代谢状态的作用DOI: 10.3967/bes2025.154 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.41Excess Body Weight and Its Influence on Colonoscopy Adherence and Findings: Results from an Opportunistic Colorectal Cancer Screening Program in Chongqing超重对结肠镜筛查依从性及病变检出的影响：来自重庆机会性结直肠癌筛查项目的结果DOI: 10.3967/bes2025.153 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.42Health Determinants in Association with Cancer Mortality from a Health Ecological Perspective健康生态视角下健康决定因素与癌症死亡率的关系DOI: 10.3967/bes2025.152 Biomed Environ Sci IF: 04.100Volume 38, Issue 12No.43Tackling Adult Obesity in China: A Time for Action应对中国成人肥胖症：行动之时DOI: 10.3967/bes2025.149 Nutrients IF: 05.000Volume 17, Issue 24No.44Hyodeoxycholic Acid Suppresses High-Fat-Diet-Promoted MC38-Syngeneic Colorectal Tumor Growth via Bile Acid Remodeling and Microbiota Modulation猪去氧胆酸通过胆汁酸重塑和肠道菌群调节抑制高脂饮食促进的MC38同源结直肠肿瘤生长DOI: 10.3390/nu17243939 Nutrients IF: 05.000Volume 17, Issue 24No.45Soluble Dietary Fiber from Highland Barley Bran Reduces Hepatic Lipid Accumulation in Mice via Gut Microbiota Modulation青稞麸皮可溶性膳食纤维通过调控肠道菌群减少小鼠肝脏脂质积累DOI: 10.3390/nu17243870 Population health metrics IF: 02.500Ahead of Print.No.46Association of loneliness and social isolation with excess risk of mental disorders in people with obesity: a prospective cohort study肥胖人群中孤独与社交隔离与精神障碍超额风险的关联：一项前瞻性队列研究DOI: 10.1186/s12963-025-00451-4 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.47Development and external validation of machine-learning based models to predict diabetic foot ulcer in diabetes population基于机器学习的糖尿病足溃疡预测模型的开发与外部验证DOI: 10.3389/fendo.2025.1692917 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.48Exploring the mechanism of Heidihuang Pill in the treatment of osteoporosis based on network pharmacology, molecular docking, and experimental validation基于网络药理学、分子对接及实验验证探讨黑地黄丸治疗骨质疏松的作用机制DOI: 10.3389/fendo.2025.1664254 Journal of nanobiotechnology IF: 12.600Ahead of Print.No.49Biomimetic cell membrane decorated calcium carbonate nanoparticles with asparaginase-metformin preloading for leukemia therapy载有天冬酰胺酶-二甲双胍的仿生细胞膜修饰碳酸钙纳米颗粒用于白血病治疗DOI: 10.1186/s12951-025-03962-2 Frontiers in neurology IF: 02.800Volume 16, Issue No.50Comparative impact of different weight loss strategies on obstructive sleep apnea: an integrated review of surgical, pharmacological, and lifestyle interventions不同减肥策略对阻塞性睡眠呼吸暂停影响的比较综述：手术、药物和生活方式干预DOI: 10.3389/fneur.2025.1719923 Molecules IF: 04.600Volume 30, Issue 24No.51Discovery and Activity Evaluation of Novel Dibenzoxazepinone Derivatives as Glycogen Phosphorylase Inhibitors新型二苯并氧氮杂䓬酮衍生物作为糖原磷酸化酶抑制剂的发现与活性评价DOI: 10.3390/molecules30244797 Molecules IF: 04.600Volume 30, Issue 24No.52Isolation, Total Synthesis and Anti-Diabetic Activity of Filiforidine from Cassytha filiformis从无根藤中分离、全合成菲力福里定及其抗糖尿病活性研究DOI: 10.3390/molecules30244763 Nutrients IF: 05.000Volume 17, Issue 24No.53Impact of the Mediterranean Diet on Glycemic Control, Body Mass Index, Lipid Profile, and Blood Pressure in Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials地中海饮食对2型糖尿病患者血糖控制、体重指数、血脂谱及血压影响的荟萃分析DOI: 10.3390/nu17243908 Frontiers in medicine IF: 03.000Volume 12, Issue No.54The impact of short-term administration of dapagliflozin on contrast-induced acute kidney injury in patients with type 2 diabetes and renal insufficiency undergoing percutaneous coronary intervention短期应用达格列净对合并肾功能不全的2型糖尿病患者经皮冠状动脉介入治疗后造影剂急性肾损伤的影响DOI: 10.3389/fmed.2025.1744473 J Clin Transl Hepatol IF: 04.200Volume 13, Issue 12No.55Quality and Quantity? The Clinical Significance of Myosteatosis in Various Liver Diseases: A Narrative Review质量还是数量？肌脂变在各种肝病中的临床意义：一篇叙述性综述DOI: 10.14218/JCTH.2025.00383 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.56Effects of fecal microbiota transplantation on glycemic and lipid profiles in overweight or obese patients with metabolic disorders: a systematic review and meta-analysis粪菌移植对超重或肥胖代谢紊乱患者血糖及血脂谱影响：一项系统评价与荟萃分析DOI: 10.3389/fendo.2025.1737543 Frontiers in microbiology IF: 04.500Volume 16, Issue No.57Gut microbiome associated with melanin deposition by supporting energy metabolism in Sichuan mountainous black-bone chickens肠道微生物组通过支持能量代谢影响四川山地乌骨鸡的黑色素沉积DOI: 10.3389/fmicb.2025.1682376 Microorganisms IF: 04.200Volume 13, Issue 12No.58Shared Gut Microbial and Functional Signatures Linking Parkinson's Disease and Type 2 Diabetes Revealed by Function-Anchored Metagenomics基于功能锚定的宏基因组学揭示连接帕金森病与2型糖尿病的共享肠道微生物及功能特征DOI: 10.3390/microorganisms13122705 Molecules IF: 04.600Volume 30, Issue 24No.59First In Vitro Human Islet Assessment of Oleanolic Acid (OA) and Its Serine Conjugate: Enhanced Solubility with Comparable Effects齐墩果酸及其丝氨酸结合物的首次体外人类胰岛评估：溶解性增强且效果相当DOI: 10.3390/molecules30244716 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.60Berberine: A Rising Star in the Management of Type 2 Diabetes-Novel Insights into Its Anti-Inflammatory, Metabolic, and Epigenetic Mechanisms小檗碱：2型糖尿病管理中的一颗新星——其抗炎、代谢与表观遗传机制的新见解DOI: 10.3390/ph18121890 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.61Emodin Enhances Rosiglitazone's Therapeutic Profile by Dual Modulation of SREBP1-Mediated Adipogenesis and PPARγ-Driven Thermogenesis大黄素通过双重调节SREBP1介导的脂肪生成与PPARγ驱动的产热作用增强罗格列酮的治疗谱DOI: 10.3390/ph18121810 Pharmaceutics IF: 05.500Volume 17, Issue 12No.62The Detrimental Effects of Crystalline Excipients: How They Jeopardize the Long-Term Stability of Freeze-Dried Polypeptide Formulations结晶性辅料的不利影响：它们如何损害冻干多肽制剂的长期稳定性DOI: 10.3390/pharmaceutics17121543 Nutrients IF: 05.000Volume 17, Issue 24No.63European Bilberry Extract Ameliorates Dietary Advanced Glycation End Products-Induced Non-Alcoholic Steatohepatitis in Rats via Gut Microbiota and Its Metabolites欧洲越橘提取物通过肠道菌群及其代谢物改善饮食晚期糖基化终末产物诱导的大鼠非酒精性脂肪性肝炎DOI: 10.3390/nu17243918 Nutrients IF: 05.000Volume 17, Issue 24No.64Milk Powder Fortified with Folic Acid and Colostrum Basic Protein Promotes Linear Growth and Improves Bone Microarchitecture in Juvenile Mice Without Adverse Metabolic Effects添加叶酸和初乳碱性蛋白的奶粉促进幼年小鼠线性生长并改善骨微结构，且无不良代谢影响DOI: 10.3390/nu17243819 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.65Comparison of different insulin resistance surrogates in predicting hyperuricemia in non-diabetic Yi residents in Yunnan Province云南非糖尿病人群中不同胰岛素抵抗替代指标预测高尿酸血症能力的比较DOI: 10.3389/fendo.2025.1523771 Int J Gen Med IF: 02.000Volume 18, Issue No.66Correlation Between Triglyceride-Glucose Index (TyG Index), Monocyte to High-Density Lipoprotein Cholesterol Ratio (MHR), and the Severity of Coronary Artery Disease甘油三酯-葡萄糖指数（TyG指数）、单核细胞与高密度脂蛋白胆固醇比值（MHR）与冠状动脉疾病严重程度的相关性DOI: 10.2147/IJGM.S570395 Lipids in health and disease IF: 04.200Ahead of Print.No.67Comparison of the TyG index, TyG-traditional obesity indices, and TyG-novel obesity indices: does increased complexity help in predicting cardiometabolic multimorbidity?比较TyG指数、TyG-传统肥胖指数与TyG-新型肥胖指数：增加复杂性有助于预测心脏代谢多病吗？DOI: 10.1186/s12944-025-02836-8 Nutrients IF: 05.000Volume 17, Issue 24No.68Pioneering Insights into the Complexities of Salt-Sensitive Hypertension: Central Nervous System Mechanisms and Dietary Bioactive Compound Interventions盐敏感性高血压的复杂机制探索：中枢神经系统通路与膳食生物活性化合物干预的新见解DOI: 10.3390/nu17243961 FCVM IF: 02.900Volume 12, Issue No.69Effects of subcutaneous or oral semaglutide on cardiovascular outcomes in patients with type 2 diabetes mellitus: a meta-analysis of randomized controlled trials皮下或口服司美格鲁肽对2型糖尿病患者心血管结局的影响：随机对照试验的荟萃分析DOI: 10.3389/fcvm.2025.1731127 J Transl Med IF: 07.500Volume 23, Issue 1No.70Comment on: "Identification of macrophage polarisation and mitochondrial-related biomarkers in diabetic retinopathy"糖尿病视网膜病变中巨噬细胞极化及线粒体相关生物标志物的识别DOI: 10.1186/s12967-025-07457-4 其他发布内容（241） More Published Articles Legal medicine IF: 01.400Ahead of Print.No.01Application of RNA sequencing to cause-of-death investigation: A pilot studyRNA测序在死因调查中的应用：一项初步研究DOI: 10.1016/j.legalmed.2025.102772 Scientific reports IF: 03.900Ahead of Print.No.02Understanding the mechanism of Crassocephalum crepidiodes (Benth.) S. Moore leaf antifibrotic activity using in vivo and in silico methods基于体内外方法探究Crassocephalum crepidiodes (Benth.) S. Moore叶抗纤维化活性的机制DOI: 10.1038/s41598-025-34489-z Virology journal IF: 03.800Ahead of Print.No.03SGLT2 inhibitors prevent long-COVID-associated cognitive and pain symptoms in type 2 diabetes patientsSGLT2抑制剂预防2型糖尿病患者长期COVID相关的认知和疼痛症状DOI: 10.1186/s12985-025-03054-5 Scientific reports IF: 03.900Ahead of Print.No.04Analysis of proteins and peptides to investigate the molecular signatures of a conventional antidiabetic herb, Boerhavia procumbens Banks ex Roxb. (Nyctaginaceae)通过分析蛋白质与肽段探究传统抗糖尿病草药Boerhavia procumbens Banks ex Roxb. (Nyctaginaceae)的分子特征DOI: 10.1038/s41598-025-16474-8 BMJ case reports IF: 00.500Volume 18, Issue 12No.05Concurrent hepatic adenomatosis and hemangiomatosis in a patient with HNF1A MODYHNF1A MODY患者并发肝腺瘤病与血管瘤病DOI: 10.1136/bcr-2025-269815 BMJ case reports IF: 00.500Volume 18, Issue 12No.06Miliary tuberculosis with hypercalcaemia-induced nephrogenic diabetes insipidus in an infant婴儿粟粒性结核伴高钙血症诱发肾性尿崩症DOI: 10.1136/bcr-2025-269609 BMJ open IF: 02.300Volume 15, Issue 12No.07Implementation of the community health system innovation project in three low- and middle-income countries: COHESION-I study protocol社区健康系统创新项目在三个低收入和中等收入国家的实施：COHESION-I研究方案DOI: 10.1136/bmjopen-2025-109433 Endocrine practice IF: 04.600Ahead of Print.No.08LOW VASOPRESSIN IN MYALGIC ENCEPHALOMYELITIS/CHRONIC FATIGUE SYNDROME肌痛性脑脊髓炎/慢性疲劳综合征中的低血管加压素水平DOI: 10.1016/j.eprac.2025.12.020 J Biomed Inform IF: 04.500Ahead of Print.No.09Integrating retrospective quality assessment with real-time guideline application to support the 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Qualitative Study on Goal Conflict Management in Emerging Adults With Type 1 Diabetes1型糖尿病年轻成人的日常自我管理：关于目标冲突管理的定性研究DOI: 10.1016/j.jcjd.2025.12.011 Psychiatry research IF: 03.900Ahead of Print.No.14Metabolic monitoring and control among patients with type 2 diabetes prescribed second generation antipsychotics接受第二代抗精神病药物治疗的2型糖尿病患者的代谢监测与控制DOI: 10.1016/j.psychres.2025.116925 Placenta IF: 02.500Ahead of Print.No.15Exploring the role of specialized pro-resolving mediators, fatty acid oxidation markers and transporters in Gestational Diabetes Mellitus (GDM) placentae探究特异性促消退介质、脂肪酸氧化标志物及转运蛋白在妊娠期糖尿病胎盘中的作用DOI: 10.1016/j.placenta.2025.12.014 Sleep medicine IF: 03.400Ahead of Print.No.16Exploring sleep outcomes in youth across settings: Are there differences based on rurality or medically underserved status in the ECHO cohort?探索不同环境下青少年的睡眠状况：基于农村或医疗服务不足状况在ECHO队列中是否存在差异？DOI: 10.1016/j.sleep.2025.108754 Tissue & cell IF: 02.500Ahead of Print.No.17Vitreous exosomes and ocular regeneration: Emerging roles in intercellular communication, biomarkers, and therapeutic delivery玻璃体外泌体与眼再生：细胞间通讯、生物标志物及治疗递送中的新兴作用DOI: 10.1016/j.tice.2025.103300 Ophthalmology IF: 09.500Ahead of Print.No.18Cardiovascular Risk and Eye Health: A Prospective Cohort Study of the Pooled Cohort Equations and Ocular Disease Incidence心血管风险与眼部健康：一项关于汇总队列方程与眼部疾病发病率的前瞻性队列研究DOI: 10.1016/j.ophtha.2025.12.021 J Diabetes Complications IF: 03.100Ahead of Print.No.19Effects of high estimated glomerular filtration rate on kidney prognosis in individuals with type 2 diabetes高估测肾小球滤过率对2型糖尿病患者肾脏预后的影响DOI: 10.1016/j.jdiacomp.2025.109255 Am J Ophthalmol IF: 04.200Ahead of Print.No.20Comment on: Glucagon-like Peptide-1 Receptor Agonist Use and Risk of Cataract Development评论：胰高血糖素样肽-1受体激动剂使用与白内障发生风险DOI: 10.1016/j.ajo.2025.11.050 Biology of sex differences IF: 05.100Ahead of Print.No.21Hormones, heat, and health: a comprehensive review of sex-based differences in brown and beige fat biology激素、热量与健康：棕色脂肪与米色脂肪生物学中基于性别差异的全面评述DOI: 10.1186/s13293-025-00787-4 Nature communications IF: 15.700Ahead of Print.No.22Phosphoproteomics of aged insulin-resistant bone identifies P70S6K phosphorylation of AFF4 as a gene-specific transcriptional regulator老年胰岛素抵抗骨骼的磷酸蛋白质组学鉴定出P70S6K对AFF4的磷酸化是一种基因特异性转录调节因子DOI: 10.1038/s41467-025-68106-4 Surg Obes Relat Dis IF: 03.800Ahead of Print.No.23The impact of hospital volume on metabolic and bariatric surgery outcomes医院手术量对代谢与减重手术结果的影响DOI: 10.1016/j.soard.2025.11.023 BMJ case reports IF: 00.500Volume 18, Issue 12No.24Delayed retrograde jejunogastric intussusception after Roux-en-Y gastrojejunostomy: an uncommon complication in an unexpected anatomyRoux-en-Y胃空肠吻合术后迟发性逆行性空肠胃套叠：一种意外解剖结构中的罕见并发症DOI: 10.1136/bcr-2025-268432 BMJ open IF: 02.300Volume 15, Issue 12No.25Impact of food accessibility on eating and anthropometric outcomes among rural parent-child dyads: a secondary data analysis of a mindful eating intervention食物可及性对农村亲子对的饮食行为和人体测量学结果的影响：一项正念饮食干预的二次数据分析DOI: 10.1136/bmjopen-2025-108076 Am J Clin Nutr IF: 06.900Ahead of Print.No.26Diet quality and nutritional adequacy during a 2-year calorie restriction intervention: the CALERIE™ 2 trial为期两年的热量限制干预期间的饮食质量与营养充足性：CALERIE™ 2试验DOI: 10.1016/j.ajcnut.2025.101182 Ophthalmology IF: 09.500Ahead of Print.No.27Rate and risk of non-arteritic anterior ischaemic optic neuropathy with semaglutide use for diabetes and weight loss: a systematic review and meta-analysis司美格鲁肽用于糖尿病和减重时的非动脉炎性前部缺血性视神经病变发生率和风险：一项系统评价与荟萃分析DOI: 10.1016/j.ophtha.2025.12.022 J Sport Health Sci IF: 10.300Ahead of Print.No.28A systematic review and meta-analyses of the relationships between active outdoor play and 24-hour movement behaviors关于主动户外游戏与24小时运动行为关系的系统综述和荟萃分析DOI: 10.1016/j.jshs.2025.101115 Pharmacological research IF: 10.500Ahead of Print.No.29Low, non-psychedelic doses of psilocybin as a novel treatment for MASLD, obesity and Type 2 Diabetes via 5-HT2B receptor-dependent mechanisms低剂量、非致幻的赛洛西宾通过5-HT2B受体依赖机制成为治疗MASLD、肥胖和2型糖尿病的新方法DOI: 10.1016/j.phrs.2025.108080 J Nutr Biochem IF: 04.900Ahead of Print.No.30Complementary mechanisms of high-carbohydrate diets and ketogenic diets restore adult hippocampal neurogenesis and cognitive function in high-fat diet induced obesity in mice高碳水化合物饮食与生酮饮食通过互补机制恢复高脂饮食诱导的肥胖小鼠成年海马神经发生与认知功能DOI: 10.1016/j.jnutbio.2025.110245 Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.31BODY COMPOSITION AND FUNCTIONAL STATUS IN THE COVID-19 RECOVERY PHASE: PREVALENCE OF SARCOPENIA AND SARCOPENIC OBESITYCOVID-19恢复期的身体成分与功能状态：肌肉减少症与肌肉减少性肥胖的患病率DOI: 10.1016/j.clnesp.2025.102877 Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.32Can the (13)C-octanoic acid breath test accurately measure gastric emptying after sleeve gastrectomy and Roux-en-Y gastric bypass? A proof-of concept analysis碳13-辛酸呼气试验能否准确测量袖状胃切除和Roux-en-Y胃旁路术后的胃排空？一项概念验证分析DOI: 10.1016/j.clnesp.2025.102891 Nutrition IF: 03.000Ahead of Print.No.33Comparing body composition techniques against an adapted multicompartment model in individuals with excess body weight不同体成分测量技术与改良多室模型在超重个体中的比较DOI: 10.1016/j.nut.2025.113033 Biochem Biophys Res Commun IF: 02.200Ahead of Print.No.34Quinones as promising agents for managing metabolic syndrome: Therapeutic and toxicological considerations醌类作为管理代谢综合征的潜力药物：治疗与毒理考量DOI: 10.1016/j.bbrc.2025.153221 Food chemistry IF: 09.800Ahead of Print.No.35Selenium-enriched chickpea beverage powders: How particle size shapes composition and functionality富硒鹰嘴豆饮料粉：粒径如何影响其成分与功能特性DOI: 10.1016/j.foodchem.2025.147692 Scientific reports IF: 03.900Volume 15, Issue 1No.36Drug-related hepatotoxicity risk in elderly patients with atrial fibrillation: insights from the nationwide Italian START registry老年心房颤动患者的药物相关性肝毒性风险：基于意大利全国性START注册研究的见解DOI: 10.1038/s41598-025-28502-8 BMJ case reports IF: 00.500Volume 18, Issue 12No.37Skull base osteomyelitis following Klebsiella pneumoniae meningitis in an immunocompromised host免疫功能低下宿主克雷伯菌肺炎链球菌脑膜炎后继发颅底骨髓炎DOI: 10.1136/bcr-2025-267719 J Atheroscler Thromb IF: 02.800Volume 33, Issue 1, Page 1-115No.38High-Sensitivity C-Reactive Protein and Residual Inflammatory Risk in Coronary Artery Disease: The Pathophysiology, Prognosis, and Emerging Therapies高敏C反应蛋白与冠状动脉疾病的残余炎症风险：病理生理、预后与新兴疗法DOI: 10.5551/jat.RV22044 J Atheroscler Thromb IF: 02.800Volume 33, Issue 1, Page 1-115No.39Critical Role of microRNA-33a/b in Cardiovascular and Metabolic Disease: Molecular Mechanisms and Therapeutic PerspectivesMicroRNA-33a/b在心血管与代谢疾病中的关键作用：分子机制与治疗前景DOI: 10.5551/jat.RV22045 Mymensingh medical journalVolume 35, Issue 1No.40Relationship between Body Mass Index and Dengue Severity in Hospitalized Adults: Evidence from Bangladesh住院成人患者体重指数与登革热严重程度的关系：来自孟加拉国的证据https://pubmed.ncbi.nlm.nih.gov/41474892 Mymensingh medical journalVolume 35, Issue 1No.41Klumpke's Palsy Following Minor Trauma: A Rare Presentation in a Young Adult轻微创伤后出现克隆普克麻痹：一名年轻成人的罕见病例https://pubmed.ncbi.nlm.nih.gov/41474925 American journal of nephrology IF: 03.200Ahead of Print.No.42Triglyceride-glucose index, systolic blood pressure and risk of tubular atrophy/interstitial fibrosis in IgA nephropathyIgA肾病患者中甘油三酯-葡萄糖指数、收缩压与肾小管萎缩/间质纤维化风险DOI: 10.1159/000550298 JMIR formative research IF: 02.100Volume 9, Issue No.43Prescribing Experiences, Potentials, and Challenges of Digital Health Applications in the Field of Hormones and Metabolism: Cross-Sectional Survey Study of Health Care Providers in Germany激素与代谢领域数字健康应用的处方经验、潜力与挑战：德国医疗保健提供者横断面调查研究DOI: 10.2196/77792 JMIR Cardio IF: 02.200Volume 9, Issue No.44Predicting Atrial Fibrillation Ablation Outcomes: Machine Learning Model Development and Validation Using a Large Administrative Claims Database预测心房颤动消融结局：基于大型行政索赔数据库的机器学习模型开发与验证DOI: 10.2196/77380 Inform Health Soc Care IF: 02.400Ahead of Print.No.45Predicting the diabetes risk by analyzing symptoms using data mining techniques运用数据挖掘技术通过症状分析预测糖尿病风险DOI: 10.1080/17538157.2025.2602517 Mymensingh medical journalVolume 35, Issue 1No.46Association of Acidosis and Inflammation with Low Serum Albumin in CKD Stages 3-5 Predialysis PatientsCKD 3-5期透析前患者酸中毒和炎症与低血清白蛋白的关联https://pubmed.ncbi.nlm.nih.gov/41474916 Mymensingh medical journalVolume 35, Issue 1No.47Association of Serum Vitamin D Status with Gestational Diabetes Mellitus: An Experience from a Tertiary Level Specialized Diabetic Hospital in Bangladesh血清维生素D状态与妊娠期糖尿病相关性的研究：来自孟加拉国一家三级专科糖尿病医院的经验https://pubmed.ncbi.nlm.nih.gov/41474908 Mymensingh medical journalVolume 35, Issue 1No.48Identification of Causes and Diagnostic Difficulty in Managing Paediatric Pancreatitis: Experience at A Tertiary Care Center of Resource-Constraint Country资源有限国家三级医疗中心管理经验：儿科胰腺炎的病因识别与诊断困境https://pubmed.ncbi.nlm.nih.gov/41474905 Mymensingh medical journalVolume 35, Issue 1No.49Trimetazidine Ameliorates Progression of Diabetic Nephropathy by Reducing Serum Creatinine Level in Streptozotocin Induced Diabetic Rats曲美他嗪通过降低链脲佐菌素诱导的糖尿病大鼠血清肌酐水平改善糖尿病肾病进展https://pubmed.ncbi.nlm.nih.gov/41474898 Mymensingh medical journalVolume 35, Issue 1No.50Prescribing Pattern of Oral Anti-diabetic Agents among Patients with Type 2 Diabetes in Outpatient Department of a Tertiary Care Hospital in Bangladesh孟加拉国某三级医院门诊2型糖尿病患者口服降糖药物的处方模式https://pubmed.ncbi.nlm.nih.gov/41474893 Mymensingh medical journalVolume 35, Issue 1No.51Assessment of Serum Ferritin in Patients with Type 2 Diabetes Mellitus评估2型糖尿病患者血清铁蛋白水平https://pubmed.ncbi.nlm.nih.gov/41474891 Mymensingh medical journalVolume 35, Issue 1No.52Association of Glycemic Gap with In-Hospital Adverse Outcome after First Attack of Acute ST Elevation Myocardial Infarction in Thrombolysed Patients血糖间隙与接受溶栓治疗的急性ST段抬高型心肌梗死患者院内不良结局的关联https://pubmed.ncbi.nlm.nih.gov/41474890 Mymensingh medical journalVolume 35, Issue 1No.53Medial Plantar Artery Flap for Heel Reconstruction: A Retrospective Observational Study足跟重建的足底内侧动脉皮瓣：一项回顾性观察研究https://pubmed.ncbi.nlm.nih.gov/41474889 PloS one IF: 02.600Volume 20, Issue 12No.54Clinical and social determinants of cardiovascular risk in a population with chronic noncommunicable diseases in Maicao, La Guajira, Colombia: 2024哥伦比亚拉瓜希拉省迈考地区慢性非传染性疾病人群心血管风险的临床与社会决定因素：2024年研究DOI: 10.1371/journal.pone.0340101 PloS one IF: 02.600Volume 20, Issue 12No.55Trixis angustifolia DC. as a potential plant for the co-management of diabetes mellitus and tuberculosisTrixis angustifolia DC.作为糖尿病与肺结核共管的潜在药用植物DOI: 10.1371/journal.pone.0339176 PloS one IF: 02.600Volume 20, Issue 12No.56The Peak Plasma Concentration (Cmax)/Minimum Inhibitory Concentration (MIC) of bedaquiline and levofloxacin with special attention to the sputum conversion in the treatment of multidrug-resistant tuberculosis in Indonesia贝达喹啉和左氧氟沙星的峰浓度/最低抑菌浓度 (Cmax/MIC) 与印度尼西亚多重耐药肺结核治疗中痰培养阴转关系的研究DOI: 10.1371/journal.pone.0336210 PloS one IF: 02.600Volume 20, Issue 12No.57Stepping forward: A study protocol for developing and validating a Malaysian diabetic foot self-care practice assessment instrument迈步向前：一项用于开发和验证马来西亚糖尿病足自我护理实践评估工具的研究方案DOI: 10.1371/journal.pone.0337754 J Am Podiatr Med Assoc IF: 00.600Volume 115, Issue 6No.58Associations of Diabetic Foot Infection with Ulcer Prognosis and Amputation Timing in Patients with Type 2 Diabetes Mellitus2型糖尿病患者足部感染与溃疡预后及截肢时机的关联DOI: 10.7547/23-230 J Am Podiatr Med Assoc IF: 00.600Volume 115, Issue 6No.59Impact of COVID-19 Pandemic on Diabetic Foot Ulcer Management in Kalamazoo, MichiganCOVID-19大流行对美国密歇根州卡拉马祖地区糖尿病足溃疡管理的影响DOI: 10.7547/24-036 J Am Podiatr Med Assoc IF: 00.600Volume 115, Issue 6No.60Canines Masticating on the Lower Extremity犬只啃食糖尿病患者足部/趾部：现象与警示DOI: 10.7547/24-071 Journal of glaucoma IF: 01.800Ahead of Print.No.61Surgical Outcomes of Ahmed Glaucoma Valve in Neovascular Glaucoma Secondary to Diabetic Retinopathy Versus Central Retinal Vein OcclusionAhmed青光眼引流阀在糖尿病视网膜病变与视网膜中央静脉阻塞所致新生血管性青光眼中的手术结局比较DOI: 10.1097/IJG.0000000000002680 PloS one IF: 02.600Volume 20, Issue 12No.62Correction: FedGAN: Federated diabetic retinopathy image generation更正：FedGAN：联邦糖尿病视网膜病变图像生成DOI: 10.1371/journal.pone.0340003 J Clin Exp Neuropsychol IF: 01.700Ahead of Print.No.63Conversion of subjective cognitive decline to MCI and dementia: a systematic review and meta-analysis of sex differences and risk factors主观认知下降向轻度认知障碍及痴呆的转化：性别差异与风险因素的系统综述和荟萃分析DOI: 10.1080/13803395.2025.2609824 Arch Gynecol Obstet IF: 02.500Volume 313, Issue 1No.64Antepartum prediction of shoulder dystocia using machine learning应用机器学习进行产前肩难产预测DOI: 10.1007/s00404-025-08271-5 The journal of physiology IF: 04.400Ahead of Print.No.65Kidney disease impairs tendon function in rats肾病损害大鼠肌腱功能DOI: 10.1113/JP289753 Epilepsia IF: 06.600Ahead of Print.No.66Drug-resistant glutamic acid decarboxylase 65-associated epilepsy: Pre-surgical evaluation and comparison to temporal lobe epilepsy of other etiology药物难治性谷氨酸脱羧酶65相关癫痫的术前评估及与其他病因颞叶癫痫的比较DOI: 10.1002/epi.70068 Annals of African medicine IF: 00.600Ahead of Print.No.67Repeated Multiple Episodes of Furunculosis in a Young Brittle Diabetic, Successfully Treated一例年轻脆性糖尿病患者反复多发疖病的成功治疗DOI: 10.4103/aam.aam_566_25 Postgraduate medical journal IF: 02.700Ahead of Print.No.68Pharmacogenetics of incretin-based therapies基于肠促胰素疗法的药物遗传学DOI: 10.1093/postmj/qgaf232 Diabetic medicine IF: 03.400Ahead of Print.No.69Progression of albumin/creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) over 24 years in people with type 2 diabetes. Drivers, potential protectors and associated mortality2型糖尿病患者24年间尿白蛋白/肌酐比值（ACR）和估算肾小球滤过率（eGFR）的进展：驱动因素、潜在保护因素及相关死亡率DOI: 10.1111/dme.70193 Small IF: 12.100Ahead of Print.No.703D-Printed Auxetic Hydrogel Dressings Reinforced With MXene and Carbonized Polymer Dots for Cascaded Antibacterial and Pro-Regenerative Effects in Wound Healing3D打印含MXene和碳化聚合物点的拉胀水凝胶敷料用于伤口愈合中的级联抗菌和促再生效应DOI: 10.1002/smll.202508633 eLifeVolume 13, Issue No.71JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney diseaseJAK-STAT通路激活损害果蝇高脂饮食慢性肾脏病模型中的肾细胞功能DOI: 10.7554/eLife.96987 J Diabetes Investig IF: 03.000Ahead of Print.No.72The biology of PKM2 in the metabolism and senescence in diabetic kidney diseasePKM2在糖尿病肾病代谢与衰老中的生物学作用DOI: 10.1111/jdi.70231 Arch Gynecol Obstet IF: 02.500Volume 313, Issue 1No.73The outcomes of pregnancy after metabolic and bariatric surgery: a literature review代谢与减重手术后妊娠结局：一项文献综述DOI: 10.1007/s00404-025-08290-2 Lung India IF: 01.200Volume 43, Issue 1No.74Impact of metabolically healthy and metabolically unhealthy obesity on cardiac arrest and mortality in pulmonary embolism hospitalizations in elderly patients with cancer代谢健康与代谢不健康肥胖对老年癌症患者肺栓塞住院期间心脏骤停及死亡率的影响DOI: 10.4103/lungindia.lungindia_134_25 Hepatology research IF: 03.400Ahead of Print.No.75Post-COVID-19 Changes in Body Composition and Adiposity in Patients With Chronic Liver Disease: A Longitudinal Study From Japan慢性肝病患者在COVID-19后身体成分与肥胖状态的变化：一项来自日本的纵向研究DOI: 10.1111/hepr.70114 J Clin Pharmacol IF: 02.300Volume 66, Issue 1No.76Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children基于群体药代动力学优化儿童静脉及肠内美沙酮给药方案DOI: 10.1002/jcph.70143 The journal of physiology IF: 04.400Ahead of Print.No.77First in-human microelectrode recordings of vagus nerve activity in heart failure心力衰竭患者迷走神经活动的微电极记录DOI: 10.1113/JP290343 Journal of periodontology IF: 03.800Ahead of Print.No.78Hyperglycemia exacerbates placental inflammation induced by Porphyromonas gingivalis-lipopolysaccharide高血糖加剧由牙龈卟啉单胞菌脂多糖诱导的胎盘炎症DOI: 10.1002/jper.70051 Diabetes care IF: 16.600Ahead of Print.No.79Metabolic Factors Modulating the Connection Between Diabetes and Pulmonary Alterations调控糖尿病与肺部改变关联的代谢因素DOI: 10.2337/dc25-2334 Computers, informatics, nursing IF: 01.900Ahead of Print.No.80A Digital Diabetes Clinic Intervention for Individuals Starting Insulin Therapy: Randomized Controlled Trial针对起始胰岛素治疗个体的数字糖尿病诊所干预：一项随机对照试验DOI: 10.1097/CIN.0000000000001439 Lung India IF: 01.200Volume 43, Issue 1No.81Burden and impact of pulmonary embolism in young adults hospitalized with sarcoidosis: Underreported data from nationwide analysis (2016-2020)住院年轻成人结节病患者中肺栓塞的负担与影响：来自全国性分析（2016-2020年）的未被充分报告的数据DOI: 10.4103/lungindia.lungindia_375_25 BMC Sports Sci Med Rehabil IF: 02.800Volume 17, Issue 1No.82Acute hematological, metabolic, and inflammatory responses to simulated-6000 ft masked versus unmasked high-intensity interval training in youth soccer players: a randomized crossover pilot study青少年足球运动员对模拟6000英尺海拔训练面罩与无面罩高强度间歇训练的急性血液学、代谢和炎症反应：一项随机交叉试验研究DOI: 10.1186/s13102-025-01426-6 Medicina IF: 02.400Volume 61, Issue 12No.83Dysregulation of Niacin-Derived NAD(+) Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes2型糖尿病中烟酰胺来源的NAD+补救途径标志物（CD38、NAMPT、SIRT1）在白蛋白尿各阶段的失调DOI: 10.3390/medicina61122089 Curēus IF: 01.300Volume 17, Issue 12No.84Morbidity in Elderly Women Undergoing Pelvic Floor Reconstruction老年女性接受盆底重建术的围手术期发病率研究DOI: 10.7759/cureus.100361 American journal of medicine openVolume 14, Issue No.85GLP-1 Receptor Agonists Initiation and Risk of Acute Pancreatitis and Pancreatic Cancer: A Real-World Comparative StudyGLP-1受体激动剂起始治疗与急性胰腺炎及胰腺癌风险：一项真实世界比较研究DOI: 10.1016/j.ajmo.2025.100114 Rev Panam Salud Publica IF: 02.200Volume 49, Issue No.86[Situation of essential conditions for the delivery of care for noncommunicable diseases in the Bolivian Chaco regionSituação das condições essenciais para a atenção a doenças não transmissíveis na região do Chaco boliviano]玻利维亚查科地区非传染性疾病护理基本条件的现状评估DOI: 10.26633/RPSP.2025.135 Clinical case reports IF: 00.600Volume 14, Issue 1No.87An Epileptic Girl With Erotomania Using Carbamazepine|Resistant to Treatment and Challenge of Starting Clozapine一名使用卡马西平的癫痫伴钟情妄想女性患者：治疗抵抗与启用氯氮平的挑战DOI: 10.1002/ccr3.71741 Frontiers in public health IF: 03.400Volume 13, Issue No.88Adherence to Mediterranean diet and physical activity practice in general population: an intersectional analysis of inequalities by sex and economic status普通人群中地中海饮食依从性与体力活动的实践：基于性别与经济状况的交叉性不平等分析DOI: 10.3389/fpubh.2025.1727223 Journal of migration and health IF: 02.900Volume 12, Issue No.89Perspectives of humanitarian actors on interprofessional care for persons living with diabetes: Lessons from Aleppo, Syria人道主义工作者对糖尿病患者跨专业护理的视角：来自叙利亚阿勒颇的经验DOI: 10.1016/j.jmh.2025.100355 Curēus IF: 01.300Volume 17, Issue 11No.90Roles of Psychiatry, Dietary, and Oncology Services in Occupational Medicine: A Comprehensive Review精神病学、营养学与肿瘤学服务在职业医学中的作用：一项综合综述DOI: 10.7759/cureus.98069 Curēus IF: 01.300Volume 17, Issue 11No.91Prevalence and Associated Factors of Glaucoma Among Adults in a Tertiary Care Center in Dubai, United Arab Emirates: A Retrospective Review阿拉伯联合酋长国迪拜一家三级医疗中心成人青光眼患病率及相关因素：一项回顾性研究DOI: 10.7759/cureus.98105 Curēus IF: 01.300Volume 17, Issue 11No.92Effective Limb Salvage Using a Distally Based Peroneus Brevis Flap for Distal Tibial Osteomyelitis使用远端蒂腓骨短肌瓣有效保肢治疗胫骨远端骨髓炎DOI: 10.7759/cureus.98065 ARYA Atherosclerosis IF: 00.600Volume 21, Issue 6No.93Six-month survival and predictors of mortality after ischemic stroke: A prospective cohort study in Iran伊朗缺血性卒中后六个月生存率及死亡预测因素：一项前瞻性队列研究DOI: 10.48305/arya.2025.45310.3060 South Asian journal of cancer IF: 00.600Volume 14, Issue 4No.94Practice Patterns and Incidence of F ebrile Neutr o penia in Patients R eceiving T riplet Drug Chemotherapeutic Regimens in G U T Cancers: Do We Need to Add WBC Growth Factors? (ForGeT GCSF Study)GU癌症患者接受三联药物化疗方案中的实践模式与发热性中性粒细胞减少症发生率：是否需要添加WBC生长因子？（ForGeT GCSF研究）DOI: 10.1055/s-0044-1789590 Frontiers in nutrition IF: 05.100Volume 12, Issue No.95Impact of α-linolenic acid supplementation on long-chain n-3 fatty acid profiles in Western, flexitarian, vegetarian, and vegan diets补充α-亚麻酸对西方、弹性素食、素食及纯素食饮食中长链n-3脂肪酸谱的影响DOI: 10.3389/fnut.2025.1727308 Korean J Community NutrVolume 29, Issue 1No.96[Association of ultra-processed food with diabetes and impaired fasting glucose in elderly populations (urban and rural): a cross-sectional study]韩国城乡老年人超加工食品摄入与糖尿病及空腹血糖受损的关联：一项横断面研究DOI: 10.5720/kjcn.2024.29.1.51 Nigerian Medical journalVolume 66, Issue 4No.97Glycemic control among People living with HIV and diabetes in Eastern Uganda: A cross-sectional study乌干达东部地区HIV合并糖尿病患者的血糖控制情况：一项横断面研究DOI: 10.71480/nmj.v66i4.984 Nigerian Medical journalVolume 66, Issue 4No.98Serum Galectin-3 as a Prognostic Biomarker in Acute Ischemic Stroke: A Comparative Cross-Sectional Study血清Galectin-3作为急性缺血性卒中预后生物标志物的比较横断面研究DOI: 10.71480/nmj.v66i4.875 NFS journal IF: 03.300Volume 41, Issue No.99Skeletal muscle disuse atrophy: protection by omega-3 polyunsaturated fatty acids骨骼肌废用性萎缩：omega-3多不饱和脂肪酸的保护作用DOI: 10.1016/j.nfs.2025.100253 J Integr Complement Med IF: 01.700Ahead of Print.No.100The Effects of Mandala Coloring Applied to Type 2 Diabetes Patients on Levels of Perceived Stress and Anxiety: A Randomized Controlled Study应用于2型糖尿病患者的曼陀罗绘画对感知压力和焦虑水平的影响：一项随机对照研究DOI: 10.1177/27683605251406492 Diabetic medicine IF: 03.400Ahead of Print.No.101Leaving better managed than when they arrived: A window of opportunity for people with diabetes admitted to hospital出院时病情管理优于入院：住院糖尿病患者的机遇之窗DOI: 10.1111/dme.70212 Diabetic medicine IF: 03.400Ahead of Print.No.102Healing through empowerment and active listening (HEALing): A mixed-methods evaluation of the feasibility and acceptability of a nurse-led self-care support intervention for people with diabetic foot ulcers通过赋能与积极倾听促进愈合：一项关于护士主导的糖尿病足溃疡患者自我护理支持干预措施的可行性、可接受性及效果混合方法研究评估DOI: 10.1111/dme.70187 Journal of cosmetic dermatology IF: 02.500Volume 25, Issue 1No.103Safety of Exogenous Recombinant Human Platelet-Derived Growth Factor-BB (rhPDGF-BB) for Medical and Cosmetic Applications: A Review外源性重组人血小板衍生生长因子-BB（rhPDGF-BB）在医学和美容应用中安全性的综述DOI: 10.1111/jocd.70636 Ann Otol Rhinol Laryngol IF: 01.200Ahead of Print.No.104Chronic Bacterial and Sicca Laryngitis: A Retrospective Cohort and Systematic Review慢性细菌性与干燥性喉炎：一项回顾性队列研究及系统综述DOI: 10.1177/00034894251405127 Gut and liver IF: 03.200Ahead of Print.No.105Increased Heart Failure Risk with Gastric Cancer Progression: A Nationwide Population-Based Cohort Study胃癌进展与心力衰竭风险增加相关：一项全国性人群队列研究DOI: 10.5009/gnl250209 Microorganisms IF: 04.200Volume 13, Issue 12No.106Fatal Congenital Toxoplasmosis with Progressive Liver Failure and Genomic Characterization of a Novel Isolate from the United States美国报告一例伴进行性肝衰竭的致死性先天性弓形虫病及其新型分离株的基因组特征分析DOI: 10.3390/microorganisms13122865 Microorganisms IF: 04.200Volume 13, Issue 12No.107Bacterial Adaptation to Stress Induced by Glyoxal/Methylglyoxal and Advanced Glycation End Products细菌对乙二醛/丙酮醛和晚期糖基化终末产物所致应激的适应DOI: 10.3390/microorganisms13122778 Microorganisms IF: 04.200Volume 13, Issue 12No.108Rhino-Orbital-Cerebral Mucormycosis Complicated by Vision Loss in a Patient with Uncontrolled Diabetes: A Case Report未控制糖尿病患者并发视力丧失的鼻-眶-脑毛霉菌病：一例报告DOI: 10.3390/microorganisms13122695 Molecules IF: 04.600Volume 30, Issue 24No.109Novel Trinorditerpene from Dysoxylum parasiticum (Osbeck) Kosterm: Leaf Extract with Cytotoxic, Antioxidant and α-Glucosidase Inhibitory Activities寄主臭椿叶片提取物中的新颖三降二萜：具有细胞毒性、抗氧化及α-葡萄糖苷酶抑制活性DOI: 10.3390/molecules30244747 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.110Risk Factors for Intolerable Postoperative Pain After Vitreoretinal Surgery Under AoA-Guided General Anesthesia with Intravenous COX-3 Inhibitors: A Post Hoc AnalysisAoA引导的全身麻醉联合静脉COX-3抑制剂下玻璃体视网膜手术后难以忍受性疼痛的风险因素：一项事后分析DOI: 10.3390/ph18121826 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.111Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process抗凋亡中国仓鼠卵巢细胞在3周补料分批培养工艺中生产度拉糖肽类似物DOI: 10.3390/ph18121896 Avicenna journal of medicineVolume 15, Issue 4No.112Burden and Factors Associated with Depression and Anxiety Disorders in Pediatric Asthma: A Cross-Sectional Study儿童哮喘患者抑郁与焦虑障碍的负担及相关因素：一项横断面研究DOI: 10.1055/s-0045-1814096 Digital health IF: 03.300Volume 11, Issue No.113A deep learning-based early prediction framework for weight management using real-world lifelog data: GRU-ODE-Bayes model development and validation study基于深度学习的体重管理早期预测框架：利用真实世界生活日志数据的GRU-ODE-Bayes模型开发与验证研究DOI: 10.1177/20552076251406656 Health science reports IF: 02.100Volume 9, Issue 1No.114Awareness of Obesity and Diabetes in Libya: Insights From a Cross-Sectional Study利比亚肥胖与糖尿病意识：一项横断面研究的启示DOI: 10.1002/hsr2.71654 Health science reports IF: 02.100Volume 9, Issue 1No.115Association Between Adiposity and Low Total Serum Bilirubin Concentration: A Retrospective, Cross-Sectional Study脂肪含量与低总血清胆红素浓度之间的关联：一项回顾性横断面研究DOI: 10.1002/hsr2.71700 Journal of migration and health IF: 02.900Volume 12, Issue No.116A scoping review of overweight and obesity prevalence and determinants among immigrant adults in Nordic countries斯堪的纳维亚国家移民成人超重与肥胖患病率及决定因素的范围综述DOI: 10.1016/j.jmh.2025.100377 Przegl?d Gastroenterologiczny IF: 02.500Volume 20, Issue 4No.117Concordance of the rapid urease test and the histopathology report in detecting Helicobacter pylori infection in a bariatric population. A retrospective cohort study减重手术人群中快速尿素酶试验与组织病理学报告检测幽门螺旋杆菌感染的一致性：一项回顾性队列研究DOI: 10.5114/pg.2025.156847 Applications in plant sciences IF: 02.400Volume 13, Issue 6No.118PlantSAM: An object detection-driven segmentation pipeline for herbarium specimensPlantSAM：一种面向植物标本、由目标检测驱动的分割流水线DOI: 10.1002/aps3.70034 Frontiers in nutrition IF: 05.100Volume 12, Issue No.119Nutritional factors and survival in a cohort of patients with myelofibrosis骨髓纤维化患者队列中的营养因素与生存分析DOI: 10.3389/fnut.2025.1704844 Korean J Community NutrVolume 29, Issue 1No.120Nutrition education programs necessary for social welfare facilities for persons with disabilities: a cross-sectional study残疾人士社会福利机构营养教育项目的必要性：一项横断面研究DOI: 10.5720/kjcn.2024.29.1.1 Frontiers in immunology IF: 05.900Volume 16, Issue No.121IL-6 as an integrative biomarker of residual inflammation and visceral adiposity in psoriasis: a VAI threshold-dependent modelIL-6作为银屑病中残余炎症和内脏脂肪的整合性生物标志物：一个VAI阈值依赖模型DOI: 10.3389/fimmu.2025.1699343 Headache IF: 04.000Ahead of Print.No.122A unifying disease model of idiopathic intracranial hypertension: A narrative review特发性颅内高血压的统一疾病模型：一篇叙述性综述DOI: 10.1111/head.70030 Gut and liver IF: 03.200Ahead of Print.No.123Artificial Intelligence Applications in the Diagnosis, Treatment, and Prognosis of Hepatocellular Carcinoma人工智能在肝细胞癌诊断、治疗和预后中的应用DOI: 10.5009/gnl250268 Microorganisms IF: 04.200Volume 13, Issue 12No.124The Prevalence of Perineal Tears Among Women Having Spontaneous Vaginal Births with Intrapartum Fever产时发热妇女自然阴道分娩时会阴撕裂的发生率DOI: 10.3390/microorganisms13122815 Sensors IF: 03.500Volume 25, Issue 24No.125Trajectories of Adherence to Study-Prescribed Physical Activity Goals in a mHealth Weight Loss InterventionmHealth体重管理干预中参与者遵循体力活动目标的轨迹研究DOI: 10.3390/s25247595 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.126The Impact of Maternal BMI on the Efficacy and Safety of Oral Misoprostol for Labor Induction母体BMI对口服米索前列醇引产的有效性和安全性的影响DOI: 10.3390/ph18121888 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.127Coixol and Sinigrin from Coix lacryma-jobi L. and Raphanus sativus L. Promote Fat Browning in 3T3-L1 Adipocytes薏苡仁中的薏苡仁酯与萝卜籽中的黑芥子苷促进3T3-L1脂肪细胞脂肪棕色化DOI: 10.3390/ph18121843 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.1286,7-Dihydroxy-4-methylcoumarin Suppresses Adipogenesis via AMPK and MAPK Signaling with In Silico Analysis of Adipogenic Proteins6,7-二羟基-4-甲基香豆素通过AMPK和MAPK信号通路抑制脂肪生成及基于脂肪生成蛋白的计算机模拟分析DOI: 10.3390/ph18121780 Nutrients IF: 05.000Volume 17, Issue 24No.129Use of Weight Loss Supplements According to the Purported Mechanisms of Action Among Polish Adults Living in an Obesogenic Environment: The Role of Sociodemographic and Health-Related Factors据宣称的作用机制分析波兰生活在致肥环境中成年人的减肥补充剂使用：社会人口与健康相关因素的作用DOI: 10.3390/nu17243963 Nutrients IF: 05.000Volume 17, Issue 24No.130Association Between Healthy Lifestyle and Cardiometabolic Risk in Higher Education Students in a Region of Peru: A Cross-Sectional Survey秘鲁某地区高等教育学生健康生活方式与心脏代谢风险的关联：一项横断面调查DOI: 10.3390/nu17243944 Nutrients IF: 05.000Volume 17, Issue 24No.131Learning from Peers: A Qualitative Study to Inform the Development of a Community Tailored Peer Support Intervention to Support Healthy Infant Growth向同伴学习：一项为制定社区定制化同伴支持干预以促进婴儿健康生长的定性研究DOI: 10.3390/nu17243941 Nutrients IF: 05.000Volume 17, Issue 24No.132Maternal Eating Styles and Restrictive Feeding Practices: Indirect Effects Through Perceived Child Appetite and Weight Concern母亲饮食风格与限制性喂养行为：通过感知儿童食欲和体重担忧的间接影响DOI: 10.3390/nu17243933 Nutrients IF: 05.000Volume 17, Issue 24No.133The Relationship of Sensory Profiles and Peripheral Biomarkers with Obesity and Eating Styles in Adolescence青少年肥胖与进食方式中感官特征及外周生物标志物的关系DOI: 10.3390/nu17243923 Nutrients IF: 05.000Volume 17, Issue 24No.134Eating Disorders in an Immigrant Population: Are Clinical Features and Treatment Outcomes Different from the Native-Born Spanish Population?移民人群的进食障碍：其临床特征与治疗结果是否与本土西班牙人群不同？DOI: 10.3390/nu17243914 Nutrients IF: 05.000Volume 17, Issue 24No.135Identifying Distinct Profiles of Nutrition Knowledge and Dietary Practices, and Their Determinants Among Adult Women: A Cross-Sectional Study识别成年女性营养知识与膳食实践的不同特征及其决定因素：一项横断面研究DOI: 10.3390/nu17243916 Nutrients IF: 05.000Volume 17, Issue 24No.136Dietary Patterns Influence Chronic Disease Risk and Health Outcomes in Older Adults: A Narrative Review膳食模式影响老年人慢性病风险与健康结局：一项叙述性综述DOI: 10.3390/nu17243910 Nutrients IF: 05.000Volume 17, Issue 24No.137Olfactory Capacity and Obesity in Chilean Adolescents智利青少年的嗅觉能力与肥胖DOI: 10.3390/nu17243903 Nutrients IF: 05.000Volume 17, Issue 24No.138The Impact of Physical Activity at School on the Nutritional Behavior of Overweight Children学校体力活动对超重儿童营养行为的影响DOI: 10.3390/nu17243905 Nutrients IF: 05.000Volume 17, Issue 24No.139Controversies and Perspectives of Time-Qualified Dietary Interventions时间限定饮食干预的争议与前景DOI: 10.3390/nu17243894 Nutrients IF: 05.000Volume 17, Issue 24No.140The Impact of Mindfulness Interventions upon Visual Attention and Attentional Bias Towards Food Cues: A Systematic Review正念干预对视觉注意及对食物线索注意偏向的影响：一项系统综述DOI: 10.3390/nu17243885 Nutrients IF: 05.000Volume 17, Issue 24No.141Early-Life Nutritional Determinants of Pediatric MASLD儿科代谢功能障碍相关脂肪性肝病的早期营养决定因素DOI: 10.3390/nu17243871 Nutrients IF: 05.000Volume 17, Issue 24No.142Clinical Implementation of Sustainable Functional Foods and Nutraceuticals in Metabolic Health: A Feasibility Study可持续功能性食品与营养素在代谢健康中的临床应用：一项可行性研究DOI: 10.3390/nu17243858 Nutrients IF: 05.000Volume 17, Issue 24No.143Lactiplantibacillus plantarum Strain 06CC2 Attenuates Fat Accumulation and Modulates the Gut Microbiota in a Mouse Model of Early-Stage Diet-Induced Obesity植物乳杆菌菌株06CC2减轻早期饮食诱导肥胖小鼠模型的脂肪积累并调节肠道菌群DOI: 10.3390/nu17243855 Nutrients IF: 05.000Volume 17, Issue 24No.144Role of Bioelectrical Impedance Analysis in Detecting Nutritional Disorders in Institutionalized Psychogeriatric Patients生物电阻抗分析在检测机构化老年精神科患者营养障碍中的作用DOI: 10.3390/nu17243839 Nutrients IF: 05.000Volume 17, Issue 24No.145Leader-Inspired Nutrition: A Framework for Promoting Healthy Nutrition Behaviors and a Nutritionally Fueled and Fit Military Force领导力驱动的营养：促进健康营养行为与构建营养驱动型军事强健力量的框架DOI: 10.3390/nu17243835 Nutrients IF: 05.000Volume 17, Issue 24No.146Determinants of the Availability of Special Diet Meals in Public Schools from Kraków (Poland): A Cross-Sectional Analysis波兰克拉科夫公立学校特殊膳食供应的决定因素：一项横断面分析DOI: 10.3390/nu17243834 Nutrients IF: 05.000Volume 17, Issue 24No.147The Role of Nutrition in the Development, Management, and Prevention of Rheumatoid Arthritis: A Comprehensive Review营养在类风湿关节炎发生、管理与预防中的作用：综合评述DOI: 10.3390/nu17243826 Nutrients IF: 05.000Volume 17, Issue 24No.148Exploring Obesity Subtypes: Cluster Analysis of Eating Behaviors, Food Addiction, and Psychopathology in Turkish Adults Seeking Obesity Treatment探索肥胖亚型：对寻求肥胖治疗的土耳其成年人的饮食行为、食物成瘾和精神病理学进行聚类分析DOI: 10.3390/nu17243823 Nutrients IF: 05.000Volume 17, Issue 24No.149Validity and Reliability of the Danish Version of the Adult Eating Behavior Questionnaire-Results from the South Danish Obesity Initiative成人进食行为问卷丹麦版的有效性和可靠性——来自南丹麦肥胖倡议的结果DOI: 10.3390/nu17243824 Nutrients IF: 05.000Volume 17, Issue 24No.150Health and Nutrition Interventions to Prevent Childhood Overweight and Obesity in Mexico and Latin America: A Systematic Review预防墨西哥及拉丁美洲儿童超重与肥胖的健康与营养干预措施：一项系统综述DOI: 10.3390/nu17243818 Nutrients IF: 05.000Volume 17, Issue 24No.151Assessment of Health Status, Emotional Well-Being, and the Prevalence of Overweight and Obesity in Children and Adolescents in the PICTURE Study (Wroclaw, Poland)PICTURE研究（波兰弗罗茨瓦夫）中儿童青少年健康状况、情感福祉及超重肥胖患病率评估DOI: 10.3390/nu17243817 Medicina IF: 02.400Volume 61, Issue 12No.152Six-Month Quality of Life and Health Outcomes After Bariatric Surgery: A Prospective Cohort Study from Latvia减重手术后六个月的生活质量与健康结局：一项来自拉脱维亚的前瞻性队列研究DOI: 10.3390/medicina61122238 Medicina IF: 02.400Volume 61, Issue 12No.153Long-Term Cancer Incidence Trends in Korea (2001-2020): An Age-Period-Cohort and Joinpoint Analysis with a Focus on Younger Cohorts韩国癌症发病率长期趋势（2001-2020）：基于年龄-时期-队列和连接点模型的分析，聚焦年轻队列DOI: 10.3390/medicina61122179 Cancer medicine IF: 03.100Volume 15, Issue 1No.154Positive Association Between Body Mass Index and the Likelihood of Reporting an Overall Cancer Diagnosis Among College Students in the United States美国大学生体重指数与自我报告癌症总体诊断可能性呈正相关DOI: 10.1002/cam4.71508 BMC public health IF: 03.600Volume 25, Issue 1No.155A preliminary study on the development of a chronic disease self-management curriculum for disability support workers: educational needs analysis针对残疾支持工作者的慢性病自我管理课程开发初步研究：教育需求分析DOI: 10.1186/s12889-025-25659-9 Journal of neuroscience research IF: 03.400Volume 104, Issue 1No.156Modulation of Magnetic Resonance Spectroscopy Levels of Glutamate and GABA by Ketamine in Treatment-Resistant Depression氯胺酮对难治性抑郁症患者磁共振波谱谷氨酸和γ-氨基丁酸水平的调节作用DOI: 10.1002/jnr.70102 Nutrients IF: 05.000Volume 17, Issue 24No.157Ophiopogon japonicus Root Extract Attenuates Obesity-Induced Muscle Atrophy Through Regulation of the PI3K-AKT-mTOR/FoxO3a Signaling Pathway and Lipid Metabolism in Mice and C2C12 Myotubes麦冬根提取物通过调节PI3K-AKT-mTOR/FoxO3a信号通路和脂质代谢减轻小鼠和C2C12肌管肥胖诱导的肌肉萎缩DOI: 10.3390/nu17243946 Nutrients IF: 05.000Volume 17, Issue 24No.158How the Intake of Pulses May Impact Metabolic Disorders and Dementia Risk: A Narrative Review脉冲摄入如何影响代谢紊乱和痴呆风险：一篇叙述性综述DOI: 10.3390/nu17243898 Nutrients IF: 05.000Volume 17, Issue 24No.159Nutrition and Physical Activity in an Interdisciplinary Approach to Migraine: A Narrative Review营养与体力活动在偏头痛跨学科治疗中的整合：一项叙述性综述DOI: 10.3390/nu17243869 Medicina IF: 02.400Volume 61, Issue 12No.160A Nationwide Analysis of Diabetes Mellitus and Intracranial Injuries: No Impact on Mortality but Prolonged Hospital Stays in Germany德国全国性分析：糖尿病与颅内损伤——对死亡率无影响但延长住院时间DOI: 10.3390/medicina61122187 Alzheimer's & dementia IF: 06.800Volume 12, Issue 1No.161Critical evaluation of real-world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation基于目标试验仿真对阿尔茨海默病药物研发管线中可再利用药物的真实世界证据进行批判性评估DOI: 10.1002/trc2.70193 Tissue barriers IF: 04.000Ahead of Print.No.162Current therapeutic strategies in the management of diabetic foot ulcers当前糖尿病足溃疡的治疗策略DOI: 10.1080/21688370.2025.2611185 Molecules IF: 04.600Volume 30, Issue 24No.163From Elixirs to Geroscience: A Historical and Molecular Perspective on Anti-Aging Medicine从长生药到老年科学：抗衰老医学的历史与分子视角DOI: 10.3390/molecules30244728 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.164Metformin Mitigates Diabetes-Driven Renal Senescence via Immunomodulation and the FABP4/FOXO1 Axis二甲双胍通过免疫调节及FABP4/FOXO1轴缓解糖尿病驱动的肾脏衰老DOI: 10.3390/ph18121834 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.165BMP-7 Treatment Ameliorates PTEN-Akt Mediated Apoptosis and Adverse Cardiac Remodeling in Ponatinib-Induced CardiotoxicityBMP-7治疗通过调控PTEN-Akt通路改善普纳替尼诱导心脏毒性中的细胞凋亡和不良心脏重构DOI: 10.3390/ph18121776 Medicina IF: 02.400Volume 61, Issue 12No.166Heparin Resistance in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Clinical Implications, and Evidence-Based Management体外循环心脏手术中的肝素抵抗：机制、临床意义与循证管理DOI: 10.3390/medicina61122088 Medicina IF: 02.400Volume 61, Issue 12No.167National Utilization and Expenditure Trends of GLP-1 Receptor Agonists and Dual GLP-1/GIP Agonist in Croatia, 2017-2024克罗地亚GLP-1受体激动剂与GLP-1/GIP双重激动剂的国家使用与支出趋势（2017-2024年）DOI: 10.3390/medicina61122210 Diabetic medicine IF: 03.400Ahead of Print.No.168Wider determinants of health are crucial confounders in benchmarking treatment standards: Diabetic ketoacidosis as an example健康广泛决定因素是基准化治疗标准中关键的混杂因素：以糖尿病酮症酸中毒为例DOI: 10.1111/dme.70209 Exp Ther Med IF: 02.300Volume 31, Issue 2No.169Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta-analyses代谢基因多态性与2型糖尿病风险：一项系统评价与荟萃分析DOI: 10.3892/etm.2025.13049 Curēus IF: 01.300Volume 17, Issue 11No.170Neutrophil-to-Lymphocyte Ratio (NLR): A Predictor of Microvascular Complications in Type 2 Diabetes Mellitus中性粒细胞与淋巴细胞比值（NLR）：2型糖尿病微血管并发症的预测指标DOI: 10.7759/cureus.98079 Diabetic medicine IF: 03.400Ahead of Print.No.171User evaluation of the Hypo-METRICS app: A tool for real-time symptom reporting of hypoglycaemia用户对Hypo-METRICS app的评估：一种用于低血糖实时症状报告的工具DOI: 10.1111/dme.70185 Molecules IF: 04.600Volume 30, Issue 24No.172Synthetic Flozins in Cancer Prevention and Combination Strategies: Structural Insights and Therapeutic Potential合成格列净类药物在癌症预防和联合策略中的应用：结构见解与治疗潜力DOI: 10.3390/molecules30244681 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.173Nerve Growth Factor in Diabetes Mellitus: Pathophysiological Mechanisms, Biomarkers and Therapeutic Opportunities糖尿病中的神经生长因子：病理生理机制、生物标志物与治疗机遇DOI: 10.3390/ph18121805 Pharmaceutics IF: 05.500Volume 17, Issue 12No.174Pharmacokinetic Landscape and Interaction Potential of SGLT2 Inhibitors: Bridging In Vitro Findings and Clinical ImplicationsSGLT2抑制剂的药代动力学图景与相互作用潜能：衔接体外发现与临床启示DOI: 10.3390/pharmaceutics17121604 Pharmaceutics IF: 05.500Volume 17, Issue 12No.175Oral Treatment of Obesity by GLP-1 and Its AnalogsGLP-1及其类似物的口服疗法治疗肥胖DOI: 10.3390/pharmaceutics17121596 BMC Med Inform Decis Mak IF: 03.800Ahead of Print.No.176Explainable extratreeclassifier model for early detection of type 2 diabetes: evidence from the PERSIAN Dena Cohort基于PERSIAN Dena Cohort证据的2型糖尿病早期检测可解释极端树分类器模型DOI: 10.1186/s12911-025-03333-9 Medicina IF: 02.400Volume 61, Issue 12No.177Adverse Pregnancy Outcomes in Women with Gestational Diabetes Using Different Diagnostic Criteria: A Study from the Northern Adriatic Region of Croatia使用不同诊断标准时妊娠期糖尿病女性的不良妊娠结局：一项来自克罗地亚北部亚得里亚海地区的研究DOI: 10.3390/medicina61122218 BMC pregnancy and childbirth IF: 02.700Ahead of Print.No.178Comparative analysis of inflammatory and metabolic biomarkers in PGDM and GDM pregnanciesPGDM 与 GDM 妊娠中炎症和代谢生物标志物的比较分析DOI: 10.1186/s12884-025-08597-7 Medicina IF: 02.400Volume 61, Issue 12No.179Cutaneous Melanoma in the Context of Aging衰老背景下的皮肤黑色素瘤DOI: 10.3390/medicina61122115 Medicina IF: 02.400Volume 61, Issue 12No.180Elevated Epicardial Adipose Tissue and Ischemic Stroke Risk: A Systematic Review and Meta-Analysis心外膜脂肪组织增多与缺血性卒中风险：一项系统评价与荟萃分析DOI: 10.3390/medicina61122128 Medicina IF: 02.400Volume 61, Issue 12No.181Improvement of Cardiometabolic Control with Dapagliflozin in Patients with Type 2 Diabetes in Primary Care: The AGORA-AP Study达格列净改善初级保健中2型糖尿病患者心脏代谢控制：AGORA-AP研究DOI: 10.3390/medicina61122087 Viruses IF: 03.500Volume 17, Issue 12No.182Cardiac Tissue Damage in a Female Animal Post-COVID Model: Relevance of Chemokine-Mediated Inflammation新冠病毒感染后女性动物模型中的心脏组织损伤：趋化因子介导炎症的相关性DOI: 10.3390/v17121629 Medicina IF: 02.400Volume 61, Issue 12No.183Pulmonary Function and Associated Prognostic Factors in Children After COVID-19: A Retrospective Cohort Study儿童COVID-19后肺功能及相关预后因素：一项回顾性队列研究DOI: 10.3390/medicina61122136 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.184Association Between DPPs-4 Inhibitors and Bullous Pemphigoid: Reporting Odds Ratio Analysis Using EudraVigilance DatabaseDPP-4抑制剂与天疱疮的关联性：基于EudraVigilance数据库的报告比值比分析DOI: 10.3390/ph18121800 American journal of medicine openVolume 14, Issue No.185The Impact of Different Antidiabetic Drugs on Fracture Risk in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials With a Focus on SGLT2 Inhibitors不同降糖药物对2型糖尿病患者骨折风险的影响：聚焦于SGLT2抑制剂的随机对照试验系统综述与网络荟萃分析DOI: 10.1016/j.ajmo.2025.100115 Avicenna journal of medicineVolume 15, Issue 4No.186Understanding Type 2 Diabetes Mellitus and the Knowledge Gaps among Future Health Care Professionals: Insights from Saudi Arabia洞察沙特阿拉伯未来医疗从业者对2型糖尿病的认知与差距DOI: 10.1055/s-0045-1812884 PCN reports :Volume 4, Issue 4No.187Stereotypical diagnostic bias for alcohol-induced ketoacidosis could lead to death: Normal blood sugar levels in SGLT2 blocker-induced severe diabetic ketoacidosis对酒精性酮症酸中毒的刻板诊断偏见可能导致死亡：SGLT2抑制剂诱发重度正常血糖性糖尿病酮症酸中毒DOI: 10.1002/pcn5.70279 Curēus IF: 01.300Volume 17, Issue 11No.188Challenges and Strategies for Successful Insulin Pump Therapy in an Elderly Patient With Type 1 Diabetes and Comorbidities: A Case Report一例老年1型糖尿病合并多种并发症患者胰岛素泵治疗的成功挑战与策略：病例报告DOI: 10.7759/cureus.98093 Curēus IF: 01.300Volume 17, Issue 11No.189Polycystic Ovary Syndrome-Associated Acne: The Interplay of Hyperandrogenism, Insulin Resistance, and Therapeutic Strategies多囊卵巢综合征相关痤疮：高雄激素血症、胰岛素抵抗与治疗策略的相互作用DOI: 10.7759/cureus.98103 Curēus IF: 01.300Volume 17, Issue 11No.190Maternal Thyroid Hormone Evaluation in Women With Gestational Diabetes Mellitus in the Second Trimester孕中期妊娠期糖尿病女性的母体甲状腺激素评估DOI: 10.7759/cureus.98107 bioRxivVolume 2025, Issue No.191Small molecule inhibitor of PPARγ acetylation promotes insulin sensitization and browning of white adipose tissue with improved safetyPPARγ乙酰化小分子抑制剂促进胰岛素增敏与白色脂肪棕色化并提升安全性DOI: 10.64898/2025.12.15.694265 bioRxivVolume 2025, Issue No.192mRNA and Protein Expression of Fetal Insulin Receptor in Breast Cancer Cell Lines胎儿胰岛素受体在乳腺癌细胞系中的mRNA及蛋白表达DOI: 10.64898/2025.12.15.694420 J Clin Transl Hepatol IF: 04.200Volume 13, Issue 12No.193Nutrient-stimulated Hormone-based Therapies: A New Frontier in the Prevention and Management of MASH-associated Hepatocellular Carcinoma营养刺激激素疗法：预防和管理MASH相关肝细胞癌的新前沿DOI: 10.14218/JCTH.2025.00303 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.194Enhancing insulin secretion by pancreatic β-cell redifferentiation: a study of the anti-diabetic effects of berberine in vitro通过胰腺β细胞再分化增强胰岛素分泌：小檗碱体外抗糖尿病作用研究DOI: 10.3389/fendo.2025.1658671 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.195Real-world glycemic outcomes of a tubeless automated insulin delivery system: a single-center observational study in Italy无管路自动胰岛素输送系统的真实世界血糖结局：一项意大利单中心观察性研究DOI: 10.3389/fendo.2025.1717249 JCEM case reportsVolume 4, Issue 1No.196Exogenous Insulin Antibody Syndrome and Subsequent Severe Subcutaneous Insulin Resistance Complicating Type 1 Diabetes外源性胰岛素抗体综合征及后续严重皮下胰岛素抵抗并发1型糖尿病DOI: 10.1210/jcemcr/luaf300 Veterinary World IF: 02.000Volume 18, Issue 11No.197Optimization of insulin-like growth factor-1 supplementation enhances oocyte quality by modulating oxidative stress and apoptotic pathways during in vitro maturation of Kacang goat oocytes优化胰岛素样生长因子-1补充通过调节氧化应激和凋亡通路提升Kacang山羊卵母细胞体外成熟质量DOI: 10.14202/vetworld.2025.3545-3560 Frontiers in immunology IF: 05.900Volume 16, Issue No.198Macrophages: friend or foe in diabetes pathogenesis and therapy巨噬细胞：糖尿病发病机制与治疗中的朋友还是敌人？DOI: 10.3389/fimmu.2025.1625391 Frontiers in immunology IF: 05.900Volume 16, Issue No.199A diet-induced obese and diabetic host phenotype reduces mosquito ZIKV infections and remodels gut metabolism饮食诱导的肥胖与糖尿病宿主表型可降低蚊子寨卡病毒感染并重塑其肠道代谢DOI: 10.3389/fimmu.2025.1704301 Future microbiology IF: 02.400Ahead of Print.No.200Superficial fungal infections in patients with diabetes. Is hyperglycemia the only associated factor?糖尿病患者浅部真菌感染：高血糖是唯一的关联因素吗？DOI: 10.1080/17460913.2025.2607353 J Clin Endocrinol Metab IF: 05.100Ahead of Print.No.201Approach to the Patient - Mitochondrial Diabetes: Contemporary Cases and Precision Medicine Approach病例精析：线粒体糖尿病——当代病例与精准医学方法DOI: 10.1210/clinem/dgaf698 Veterinary sciences IF: 02.300Volume 12, Issue 12No.202Evaluation of Pancreatic Endocrine Reprogramming in Diabetic Cats糖尿病猫胰腺内分泌重编程的评估DOI: 10.3390/vetsci12121167 Microorganisms IF: 04.200Volume 13, Issue 12No.203Glucose-Lowering Effects and Safety of Bifidobacterium longum CKD1 in Diabetic Dogs and Cats长双歧杆菌CKD1在糖尿病犬和猫中的降血糖效应及安全性DOI: 10.3390/microorganisms13122881 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.204Role of the Insulin Receptor in Mediating Cytosolic Delivery of Proteins by a Modified Cell-Penetrating Peptide胰岛素受体在介导修饰型细胞穿透肽递送蛋白质至胞质中的作用DOI: 10.3390/ph18121885 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.205An Ongoing Search for Multitarget Ligands as Potential Agents for Diabetes Mellitus and Its Long-Term Complications: New Insights into (5-Arylidene-4-oxothiazolidin-3-yl)alkanoic Acid Derivatives对糖尿病及其长期并发症潜在多靶点药物的持续探索：关于（5-芳亚甲基-4-氧代噻唑烷-3-基）链烷酸衍生物的新见解DOI: 10.3390/ph18121863 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.206Challenge of Corneal Ulcer Healing: A Novel Conceptual Framework, the "Triad" of Corneal Ulcer Healing/Corneal Neovascularization/Intraocular Pressure, and Avascular Tendon Healing, for Evaluation of Corneal Ulcer Therapy, Therapy of Neovascularization, Glaucoma Therapy, and Pentadecapeptide BPC 157 Efficacy角膜溃疡愈合的挑战：一种新的概念框架——“三联征”（角膜溃疡愈合↔角膜新生血管↔眼内压）以及无血管肌腱愈合——用于评价角膜溃疡治疗、新生血管治疗、青光眼治疗和十五肽BPC 157的有效性DOI: 10.3390/ph18121822 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.207Curcumin and Tetrahydrocurcumin as Multi-Organ Modulators of the Adipose Tissue-Gut-Liver Axis: Mechanistic Insights, Therapeutic Potential, and Translational Challenges姜黄素与四氢姜黄素作为脂肪组织-肠道-肝脏轴的多器官调节剂：机制见解、治疗潜力与转化挑战DOI: 10.3390/ph18121791 Pharmaceutics IF: 05.500Volume 17, Issue 12No.208Systematic Development and Characterization of Enzyme-Free, Borax-Crosslinked Microneedles for Glucose-Responsive Insulin Delivery and In Vivo Glycemic Mitigation用于葡萄糖响应性胰岛素递送与体内血糖调节的无酶、硼砂交联微针的系统性开发与表征DOI: 10.3390/pharmaceutics17121578 Pharmaceutics IF: 05.500Volume 17, Issue 12No.209Inulin Reverses Intestinal Mrp2 Downregulation in a Diet-Induced Obesity Mouse Model: Role of Intestinal Microbiota as a Pivotal Modulator菊粉逆转饮食诱导肥胖小鼠模型中肠道Mrp2下调：肠道微生物群作为关键调节因子的作用DOI: 10.3390/pharmaceutics17121575 Pharmaceutics IF: 05.500Volume 17, Issue 12No.210Nanoparticle-Based Oral Insulin Delivery: Challenges, Advances, and Future Directions基于纳米颗粒的口服胰岛素递送：挑战、进展与未来方向DOI: 10.3390/pharmaceutics17121563 Pharmaceutics IF: 05.500Volume 17, Issue 12No.211In Silico Hypothesis Testing in Drug Discovery: Using Quantitative Systems Pharmacology Modeling to Evaluate the Therapeutic Value of Proinsulin Conversion to Insulin Therapy for Type 2 Diabetes Mellitus药物发现中的计算机模拟假设检验：使用定量系统药理学模型评估胰岛素原转化为胰岛素疗法对2型糖尿病的治疗价值DOI: 10.3390/pharmaceutics17121522 Nutrients IF: 05.000Volume 17, Issue 24No.212Mice Condition Cephalic Insulin Responses to the Flavor of Different Laboratory Chows小鼠对不同实验室饲料风味建立头期胰岛素反应DOI: 10.3390/nu17243880 Nutrients IF: 05.000Volume 17, Issue 24No.213Metabolic and Neuroenergetic Effects of Intranasal Vitamin C Application in the Human Brain鼻内应用维生素C对人脑代谢与神经能量学的影响DOI: 10.3390/nu17243875 Nutrients IF: 05.000Volume 17, Issue 24No.214Prediction of Postprandial Blood Glucose Variability Using Machine Learning in Frequent Insulin Injection Therapy with a Simplified Carbohydrate Counting Model使用机器学习和简化碳水化合物计数模型预测频繁胰岛素注射治疗中的餐后血糖变异性DOI: 10.3390/nu17243832 Nutrients IF: 05.000Volume 17, Issue 24No.215Gut Microbiota and Metabolic Modulation by Slow-Release Protein Substitutes in Phenylketonuria: Findings from the PREMP Study缓释蛋白质替代品对苯丙酮尿症患者肠道微生物群及代谢的调节作用：PREMP研究结果DOI: 10.3390/nu17243829 Micromachines IF: 03.000Volume 16, Issue 12No.216Pump-Free Insulin Delivery via an SLA-Printed Hollow Microneedle Patch with an Integrated Self-Sealing Reservoir基于SLA打印中空微针贴片结合自密封储库的无泵胰岛素递送系统DOI: 10.3390/mi16121322 Medicina IF: 02.400Volume 61, Issue 12No.217The Prevalence of H. pylori Among Jordanian Type 2 Diabetic Patients and Its Association with ABO Blood Group幽门螺杆菌在约旦2型糖尿病患者中的流行情况及其与ABO血型的关联DOI: 10.3390/medicina61122167 Medicina IF: 02.400Volume 61, Issue 12No.218Can Insulin Drops Accelerate Corneal Healing After Corneal Cross-Linking? A Preliminary Case Series胰岛素滴眼液能加速角膜交联术后的角膜愈合吗？一项初步病例系列研究DOI: 10.3390/medicina61122101 Nutrients IF: 05.000Volume 17, Issue 24No.219Nutrient-Induced Remodeling of the Adipose-Cardiac Axis: Metabolic Flexibility, Adipokine Signaling, and Therapeutic Implications for Cardiometabolic Disease营养素诱导的脂肪-心脏轴重塑：代谢灵活性、脂肪因子信号与心脏代谢疾病的治疗启示DOI: 10.3390/nu17243945 Nutrients IF: 05.000Volume 17, Issue 24No.220C. cochlearium 2316 Ameliorates High-Fat Diet-Induced Obesity and Metabolic Syndrome Risk Factors via Enhanced Energy Expenditure and Glucose HomeostasisC. cochlearium 2316通过增强能量消耗和血糖稳态改善高脂饮食诱导的肥胖与代谢综合征风险因素DOI: 10.3390/nu17243848 Medicina IF: 02.400Volume 61, Issue 12No.221A Comparison of Periodontal Health in Elderly Individuals with and Without Metabolic Syndrome: A Retrospective Study代谢综合征与老年牙周健康状况比较：一项回顾性研究DOI: 10.3390/medicina61122200 Medicina IF: 02.400Volume 61, Issue 12No.222Nutrition Counseling Frequency and Telehealth Integration on Cardiometabolic Outcomes in Metabolic Syndrome: A Randomized Controlled Trial in Turkey营养咨询频率与远程医疗整合对代谢综合征心脏代谢结果的影响：一项土耳其随机对照试验DOI: 10.3390/medicina61122124 Medicina IF: 02.400Volume 61, Issue 12No.223Prevalence of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Lithuanian Adults: Insights from a Nationwide Real-World Study Using Electronic Health Records立陶宛成年人心血管-肾脏-代谢综合征患病率：基于全国电子健康记录的真实世界研究见解DOI: 10.3390/medicina61122106 Investig Clin Urol IF: 02.100Volume 67, Issue 1No.224Metabolic syndrome and its components as independent risk factors for nocturia: A national cross-sectional analysis代谢综合征及其组分作为夜尿症的独立危险因素：一项全国性横断面分析DOI: 10.4111/icu.20250261 Case Rep Oncol Med IF: 00.600Volume 2025, Issue No.225Hypertriglyceridemia-Induced Acute Pancreatitis Associated with Ruxolitinib for Hemophagocytic Lymphohistiocytosis: A Case Report鲁索替尼治疗噬血细胞性淋巴组织细胞增生症相关的高甘油三酯血症诱发急性胰腺炎：一例病例报告DOI: 10.1155/crom/7271334 Veterinary World IF: 02.000Volume 18, Issue 11No.226Integrative metabolomics and hormonal profiling reveal biomarkers of milk yield efficiency in Sapera dairy goats under tropical conditions整合代谢组学与激素谱分析揭示热带条件下Sapera奶山羊产奶效率的生物标志物DOI: 10.14202/vetworld.2025.3594-3606 Molecules IF: 04.600Volume 30, Issue 24No.227Design and Biological Evaluation of Monoterpene-Conjugated (S)-2-Ethoxy-3-(4-(4-hydroxyphenethoxy)phenyl)propanoic Acids as New Dual PPARα/γ Agonists单萜共轭的(S)-2-乙氧基-3-(4-(4-羟基苯乙氧基)苯基)丙酸作为新型双重PPARα/γ激动剂的设计与生物活性评估DOI: 10.3390/molecules30244775 Molecules IF: 04.600Volume 30, Issue 24No.228Protective Metabolic Effects of Chickpea Sprout Against Obesity-Induced Insulin Resistance and Hypoestrogenism in Rats鹰嘴豆芽对肥胖诱导的胰岛素抵抗及低雌激素血症大鼠模型的保护性代谢效应DOI: 10.3390/molecules30244673 Nutrients IF: 05.000Volume 17, Issue 24No.229Refining MASLD Phenotypes: Clinical, Metabolic, and Elastographic Differences Between Adipose Tissue Dysfunction and Obesity-Driven Disease细化MASLD表型：脂肪组织功能障碍与肥胖驱动疾病之间的临床、代谢与弹性成像差异DOI: 10.3390/nu17243940 Nutrients IF: 05.000Volume 17, Issue 24No.230Opuntia dillenii as a Nutraceutical and Dietary Resource for Disease Prevention and Management: A Systematic ReviewOpuntia dillenii作为营养保健品与膳食资源在疾病预防和管理中的作用：一项系统综述DOI: 10.3390/nu17243915 Nutrients IF: 05.000Volume 17, Issue 24No.231Redox Response in Postoperative Metabolic and Bariatric Surgery: New Insights into Cardiovascular Risk Markers代谢和减重术后的氧化还原反应：心血管风险标志物的新见解DOI: 10.3390/nu17243821 Medicina IF: 02.400Volume 61, Issue 12No.232Impact of Obstructive Sleep Apnea-Hypopnea Syndrome Severity on Heart Rate Variability and QTc Interval in Hypertensive Patients阻塞性睡眠呼吸暂停低通气综合征严重程度对高血压患者心率变异性及QTc间期的影响DOI: 10.3390/medicina61122221 Medicina IF: 02.400Volume 61, Issue 12No.233Cardiometabolic Risk Factors Among Adults in a Rural Amazonian Peruvian Population秘鲁农村亚马逊地区成年人心血管代谢风险因素DOI: 10.3390/medicina61122206 Pharmaceuticals IF: 04.800Volume 18, Issue 12No.234Rosuvastatin Versus Atorvastatin for Cardiovascular Disease Risk in Patients with Type 2 Diabetes: A Korean Cohort Study瑞舒伐他汀与阿托伐他汀对2型糖尿病患者心血管疾病风险的比较：一项韩国队列研究DOI: 10.3390/ph18121860 Nigerian Medical journalVolume 66, Issue 4No.235Assessment of Peripheral Arterial Disease among Type 2 Diabetes Patients in Calabar, Nigeria尼日利亚卡拉巴尔2型糖尿病患者外周动脉疾病评估DOI: 10.71480/nmj.v66i4.560 Medicina IF: 02.400Volume 61, Issue 12No.236Serum Trimethylamine N-Oxide Levels Are Associated with Peripheral Artery Disease in Patients with Type 2 Diabetes Mellitus血清三甲胺N-氧化物水平与2型糖尿病患者的周围动脉疾病相关DOI: 10.3390/medicina61122243 JEADV IF: 08.000Ahead of Print.No.237French guidelines on systemic treatments for moderate-to-severe psoriasis in adults: Update 2025法国成人中重度银屑病系统治疗指南：2025年更新DOI: 10.1111/jdv.70263 Front Mol Biosci IF: 04.000Volume 12, Issue No.238Retraction: Circular ribonucleic acid circFTO promotes angiogenesis and impairs blood-retinal barrier via targeting the miR-128-3p/Thioredoxin interacting protein axis in diabetic retinopathy撤稿：环状RNA circFTO通过靶向miR-128-3p/硫氧还蛋白相互作用蛋白轴促进血管生成并损害血-视网膜屏障：糖尿病视网膜病变研究DOI: 10.3389/fmolb.2025.1727243 Pharmaceutics IF: 05.500Volume 17, Issue 12No.239Enhanced Ocular Delivery of Epalrestat Using Nanostructured Lipid Carrier Laden Soft Contact Lens利用载有纳米结构脂质载体的软性接触镜增强依帕司他的眼部递送DOI: 10.3390/pharmaceutics17121515 Medicina IF: 02.400Volume 61, Issue 12No.240Proliferative Diabetic Retinopathy in Young-Onset Type 1 Diabetes in Croatia: Risk Factors and a Predictive Economic Model for National Screening克罗地亚年轻起病1型糖尿病患者中增生性糖尿病视网膜病变的风险因素及全国筛查预测经济模型DOI: 10.3390/medicina61122168 BMC infectious diseases IF: 03.000Volume 25, Issue 1No.241Remdesivir safety and clinical outcomes in pediatric COVID-19: a retrospective study瑞德西韦在儿科COVID-19患者中的安全性与临床结局：一项回顾性研究DOI: 10.1186/s12879-025-12155-z 179 Diabetes Mellitus(DM) 糖尿病 120 Obesity 肥胖症 71 Insulin 胰岛素 31 Type 2 diabetes mellitus(T2DM) 2型糖尿病 18 Metabolic Syndrome 代谢综合征 11 Hypoglycemic Agents 降糖药 10 Diabetic Retinopathy 糖尿病视网膜病 9 Metformin 二甲双胍 8 Diabetic Foot 糖尿病足 7 Diabetic Kidney Disease(DKD) 糖尿病肾脏病 6 Gestational Diabetes Mellitus(GDM) 妊娠糖尿病 5 Glucagon-Like Peptide-1 Receptor Agonists(GLP-1RA) 胰高血糖素样肽-1受体激动剂 4 Type 1 diabetes mellitus(T1DM) 1型糖尿病 2 Liraglutide 利拉鲁肽 2 Semaglutide 司美格鲁肽 2 Diabetic Neuropathies 糖尿病性神经病变 2 gamma-Aminobutyric Acid(GABA) γ-氨基丁酸 2 Sodium-Glucose Transporter 2 Inhibitors(SGLT-2i) 钠-葡萄糖协同转运蛋白2抑制剂 2 Dapagliflozin 达格列净 2 Diabetes Complications 糖尿病并发症 2 Diabetic acidosis 糖尿病性酸中毒 1 Dulaglutide 度拉糖肽 1 Gastrointestinal lipase inhibitor 胃肠道脂肪酶抑制剂 1 Orlistat 奥利司他 1 Diabetes mellitus in pregnancy 妊娠期糖尿病 1 Dipeptidyl-Peptidase IV Inhibitors(DPP-4i) 二肽基肽酶-4抑制剂 1 Vildagliptin 维格列汀 1 Gabapentin 加巴喷丁 编辑：天纳乾坤 审校：天纳乾坤