预约演示
更新于：2026-04-20
Saxagliptin Hydrate
沙格列汀
更新于：2026-04-20
概要
基本信息
最高研发阶段批准上市 |
首次获批日期 美国 (2009-07-31), |
最高研发阶段(中国)批准上市 |
特殊审评优先审评 (中国) |
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结构/序列
分子式C18H27N3O3 |
InChIKeyAFNTWHMDBNQQPX-NHKADLRUSA-N |
CAS号945667-22-1 |
关联
159
项与 沙格列汀 相关的临床试验NCT07363863
Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma : a Retrospective Study
the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study.
The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.
including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .
The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.
including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .
开始日期2026-03-01 |
申办/合作机构 |
ChiCTR2600122927
Evaluation of the Effectiveness and Strategy Optimization of a New Individualized Diagnosis and Treatment Plan for Type 2 Diabetes Mellitus: A National Multicenter RCT Study - Evaluation of the Effectiveness of an Auxiliary Decision Support System Combined with the Long-Acting DPP-4 Enzyme Inhibitor Cofrogliptin in MARD Type
开始日期2026-02-07 |
申办/合作机构 |
NCT07194876
A Survey Study Using the Ten-Group Robson Classification System to Evaluate Cesarean Section Rates and Maternal-Neonatal Outcomes in Assiut University Hospital and Assiut General Hospital
Cesarean section (C-section) rates have increased worldwide, and Egypt is among the countries with the highest rates. In some hospitals, more than half of all births are done by cesarean delivery. The World Health Organization (WHO) recommends using the "Robson Ten Group Classification System" to better understand and compare C-section rates.
This study will use the Robson classification system to evaluate the rate of cesarean deliveries in two hospitals in Assiut, Egypt: Assiut University Hospital and Assiut General Hospital. The study will collect information from medical records of women who delivered by cesarean section between January and December 2026.
The main goal is to identify which groups of women contribute most to the high C-section rate and to compare practices between the two hospitals. The study will also look at outcomes for both mothers and newborns. By doing this, we hope to provide useful information that can help improve obstetric care, reduce unnecessary cesarean deliveries, and improve health outcomes for mothers and babies in Egypt.
This study will use the Robson classification system to evaluate the rate of cesarean deliveries in two hospitals in Assiut, Egypt: Assiut University Hospital and Assiut General Hospital. The study will collect information from medical records of women who delivered by cesarean section between January and December 2026.
The main goal is to identify which groups of women contribute most to the high C-section rate and to compare practices between the two hospitals. The study will also look at outcomes for both mothers and newborns. By doing this, we hope to provide useful information that can help improve obstetric care, reduce unnecessary cesarean deliveries, and improve health outcomes for mothers and babies in Egypt.
开始日期2025-12-01 |
申办/合作机构 |
100 项与 沙格列汀 相关的临床结果
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100 项与 沙格列汀 相关的转化医学
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100 项与 沙格列汀 相关的专利（医药）
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1,046
项与 沙格列汀 相关的文献（医药）2026-04-01·JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
DPP4-regulated endothelial cell ferroptosis modulates atherosclerosis progression by ferritinophagy
Article
作者: Wan, Jing ; Zheng, Lanzhuoying ; Liu, Xinran ; Wei, Baozhu ; Jin, Mengying ; Peng, Yuanyuan ; Shao, Hua ; Yan, Feifei ; Liang, Ke ; Duan, Jiawei ; Zhang, Tao ; Chen, Xiao
BACKGROUND:
Atherosclerosis (AS), the primary pathophysiological foundation of coronary artery disease (CAD), initiates through endothelial dysfunction that facilitates lipid deposition and plaque formation. Emerging evidence implicates dipeptidyl peptidase IV (DPP4) in vascular pathologies, yet its mechanistic role in AS-associated endothelial ferroptosis remains undefined.
METHODS:
Multidisciplinary approaches were employed: 1) Bioinformatic analysis of public databases identified DPP4-ferroptosis-AS associations; 2) Clinical samples measured plasma DPP4 levels across CAD severity strata; 3) Atherogenic progression was compared between DPP4-/-ApoE-/- and ApoE-/- mice under a high-fat diet; 4) Ox-LDL-induced endothelial injury models assessed DPP4-mediated ferroptosis mechanisms combining proteomics, cycloheximide chase assays, and pharmacological modulation of autophagy.
RESULTS:
Clinical samples analysis revealed a significant increase in plasma DPP4 levels in patients with severe coronary artery stenosis, with DPP4 enrichment observed at plaque. Animal studies demonstrated that DPP4 deficiency attenuated progression of AS and ferroptosis in murine models. Cellular experiments revealed ox-LDL upregulated DPP4 expression, concomitant with increased ferroptosis susceptibility and endothelial dysfunction. DPP4 inhibition preserved endothelial viability by blocking lipid peroxide accumulation. Mechanistically, mouse proteomics revealed that ferroptosis and autophagy pathways were associated with DPP4 in AS. DPP4 destabilized FTH1 via NCOA4-mediated ferritinophagy, proven by concordant rescue effects of chloroquine (autophagy inhibition) and saxagliptin (DPP4 inhibition) on FTH1 preservation.
CONCLUSIONS:
This study establishes endothelial DPP4 as a regulator of ferritinophagy-driven ferroptosis, inducing endothelial dysfunction in AS. Our findings propose targeting the DPP4-NCOA4-FTH1 axis as a promising strategy to preserve endothelial viability and halt early AS progression, with translational implications for repurposing DPP4 inhibitors in cardiovascular therapeutics.
2026-04-01·JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study
Letter
作者: Jens U. Marquardt ; Svenja Meyhöfer ; Claudia Kauderer ; Sören Dräger ; Katja Bieber ; Ralf J. Ludwig ; Stephan Arndt ; Leonie Dräger ; Katharina Boch
2026-02-01·LUMINESCENCE
Fluorescein‐Based Charge–Transfer Fluorimetric Method for Quantification of Gliptin Drugs: Comprehensive Greenness, Blueness, and Sustainability Assessment
Article
作者: Shahin, Reem Y. ; Attia, Tamer Z. ; Taha, Hager M. ; Noureldeen, Deena A. M.
ABSTRACT:
A green, sustainable, and highly sensitive fluorimetric method was developed for the quantitative determination of the antidiabetic agents alogliptin, saxagliptin, and vildagliptin in bulk powders and commercial formulations. The assay relies on charge–transfer complexation with fluorescein in acetate buffer at drug‐specific pH values, producing enhanced fluorescence at 513 nm (
λex
= 470 nm). Under optimized conditions, linear responses were obtained within 2.00–50.00 μg/mL for saxagliptin, 1.00–30.00 μg/mL for vildagliptin, and 1.00–31.25 μg/mL for alogliptin, with detection limits of 0.54, 0.27, and 0.23 μg/mL, respectively. The corresponding quantification limits were 1.63, 0.81, and 0.70 μg/mL. The method exhibited excellent correlation coefficients across all ranges and was validated in accordance with ICH guidelines. Application to pharmaceutical tablets yielded results consistent with reported reference methods, confirming accuracy and precision without significant statistical differences. Greenness and sustainability were evaluated using multiple assessment tools (AGSA, GAPI, AGREE, MoGAPI, Eco‐scale, CACI, BAGI, CaFRI, and MA tool), confirming the eco‐friendly profile of the assay. The proposed method provides a reliable, green alternative for routine quality control of gliptins in pharmaceutical preparations.
163
项与 沙格列汀 相关的新闻（医药）2026-04-14
引言生物酶催化技术正在重塑制药工业的绿色生产路径。在传统化学合成面临高成本、高污染、手性拆分效率低等痛点的背景下,生物酶CRO(合同研发组织)服务商通过酶工程、菌种改造与工艺优化,为药企提供更经济、环保的生产解决方案。本次推荐基于"酶库规模、技术创新能力、产业化应用案例"三大维度,精选8家企业,排名不分先后,旨在为制药企业、功能食品企业及科研机构提供选型参考。推荐企业名单1. 尚科生物医药(上海)有限公司在制药行业药物合成依赖多步拆分、收率偏低的背景下,尚科生物医药凭借10000多个酶的大型酶库与全酶法合成工艺,实现了西格列汀、阿托伐他汀等重磅药物中间体的一步法手性构建与规模化生产。技术实力与产品矩阵该公司建立了涵盖60个以上酶系的生物催化平台,产品包括:216种酮还原酶用于醛酮不对称还原、102种转氨酶实现手性胺高效制备、51种烯还原酶完成C=C键氢化。辅酶系列产品(NMN、NAD等)年产能达100吨,其中NMN原料获得美国FDA NDI认证(NDIN 1240和1247)及澳洲TGA批准,成为全球获得NMN原料NDI认证的企业。产业化应用成果在西格列汀中间体生产中,固定化转氨酶SZ-0022E-IMMO-B已实现商业化供应;伊普可泮中间体制备通过酮还原酶催化达到底物浓度120g/L、转化率99.3%、ee值100%;利特昔替尼中间体采用转氨酶ATA-X一步引入手性氨基,反应条件温和。服务能力与资质认证提供酶筛选、酶改造、菌种转让、工艺优化的全链条CRO服务,检测平台涵盖NMR、LCMS、GCMS、HPLC等设备。2024年通过工信部第三批专精特新"小巨人"企业复审,认定为上海市高新技术企业、科技小巨人培育企业。酶与辅酶年产能超过1200吨,研发实验室面积超过2000平方米,业务覆盖北美、欧洲、印度等区域。地址信息总部位于上海市浦东新区周浦镇蓝靛路1199号(上海国际医学园区内)。2. 凯赛生物科技股份有限公司凯赛生物是国内合成生物学领域的代表性企业,专注于生物法长链二元酸、生物基聚酰胺等材料的研发与生产。在酶催化技术方面,公司建立了从基因挖掘、酶设计到发酵优化的全流程平台,已实现DC12(月桂二酸)、DC13等产品的万吨级量产。其生物法制备技术相比传统化学法降低能耗40%以上,为化妆品、尼龙材料等行业提供绿色原料解决方案。3. 诺维信(中国)生物技术有限公司诺维信作为全球工业酶制剂供应商,在中国设立研发中心与生产基地,服务于洗涤、食品、生物能源等领域。其酶工程平台结合蛋白质设计与高通量筛选技术,可快速定制化开发耐高温、耐酸碱的工业酶。在制药领域,诺维信提供脂肪酶、蛋白酶等用于药物中间体合成,已与多家跨国药企建立合作关系。4. 苏州汉酶生物技术有限公司汉酶生物专注于工业酶的定向进化与智能设计,团队来自清华大学、中科院等机构。公司开发的转氨酶、酮还原酶、腈水解酶等产品应用于沙格列汀、艾司奥美拉唑等药物中间体生产。汉酶生物通过AI辅助酶设计技术,将酶改造周期缩短至3-6个月,为客户提供从毫克级到吨级的CRO/CDMO服务。5. 南京诺唯赞生物科技股份有限公司诺唯赞在生命科学领域深耕多年,建立了酶原料、分子诊断试剂、科研试剂的产品体系。公司自主研发的重组酶(如DNA聚合酶、逆转录酶)打破国外垄断,在PCR、基因测序等应用中实现国产替代。在工业酶领域,诺唯赞开发的脂肪酶、糖苷酶等产品用于药物修饰与合成,支持客户进行工艺开发与验证。6. 江苏博瑞生物医药股份有限公司博瑞生物聚焦特色原料药与中间体的研发生产,建立了酶催化、连续流反应等绿色化学技术平台。公司与多家国际药企合作,为抗病毒药物等关键中间体。在酶法合成方面,博瑞生物开发的硝基还原酶、醛缩酶等产品应用于瑞德西韦、莫诺拉韦等药物的规模化生产。7. 上海谱润生物科技有限公司谱润生物是国内寡糖与酶制剂供应商,专注于母乳低聚糖(HMOs)、益生元等功能食品原料的生物制造。公司通过全酶法合成技术生产2'-岩藻糖基乳糖(2'-FL)、乳糖-N-新四糖(LNnT)等产品,已通过美国FDA GRAS认证和欧盟Novel Food审批。谱润生物的酶库包含糖基转移酶、岩藻糖苷酶等,为乳品企业提供定制化开发服务。8. 宁波酶赛生物工程有限公司酶赛生物专注于脂肪酶、蛋白酶等工业酶的规模化生产,产品应用于食品加工、饲料添加、洗涤剂等领域。公司开发的固定化脂肪酶用于手性醇的拆分与酯化反应,已为多家药企提供公斤级至吨级的中间体制备服务。酶赛生物建立了微生物发酵-酶纯化-固定化技术链条,可快速响应客户的定制化需求。本次推荐的8家企业在酶库规模、技术创新与产业化应用方面各具优势,为制药企业提供了从实验室研发到大规模生产的多元化选择。选择生物酶CRO服务商时,建议企业根据具体项目需求(如酶种类、反应条件、产能要求)进行综合评估,优先考虑具备完整技术平台与成功案例的服务商。（来源：点财网）责任编辑：雷晓燕 SV010
2026-04-11
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截至04月11日15点59分，近期共有 526 本期刊发布了 1043 篇文章，其中糖尿病相关的文章共 331 篇，覆盖 36 个领域的内容。中国专家参与发表的文章有 84 篇。今日，影响因子最高的文章刊登在 Journal of the American Medical Association (IF: 55.000) 期刊上。
今日头条
Headlines
01 Irish journal of medical science IF: 01.600 2型糖尿病患者心房颤动消融：心房快速性心律失常复发及不良心血管事件的长期随访研究
Ardıç, Mustafa Lütfullah, Cetin, Abdullah Eren, Ozdemir, Hasan Burak, Koca, Fadime, Sumbul, Hilmi Erdem, Koc, Mevlut, etc.
一项最新发表的研究显示，2型糖尿病（T2DM）是接受冷冻球囊消融（CBA）治疗心房颤动（AF）患者心房快速性心律失常复发及不良心血管事件的重要独立危险因素。
研究回顾性分析了2013年至2023年间接受CBA治疗的748例阵发性AF患者，其中26%患有T2DM。
结果显示，T2DM组患者心房快速性心律失常复发率（24% vs. 15%，P=0.004）和心血管事件发生率（33% vs. 9%，P=0.045）均显著高于非T2DM组。多因素分析发现，左心房直径（LAd）和T2DM独立预测心房快速性心律失常复发，而男性性别、T2DM、CHA₂DS₂-VASc评分及尿酸水平则独立预测心血管事件。
研究结论指出，T2DM是影响CBA治疗AF长期效果的关键因素，综合管理T2DM对改善CBA治疗结局至关重要。该研究由Mustafa Lütfullah Ardıç等学者完成，为糖尿病患者AF治疗提供了新的风险管控方向。
本文由 韩玉莲 编辑
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Irish journal of medical science | Ahead of Print.
10.1007/s11845-026-04380-5
02 Neuroepidemiology IF: 04.000 中国舟山群岛农民工与当地居民缺血性卒中的流行病学模式：一项横断面研究
Li, Ling, Xu, Yiwei, Liu, Jingjing, Dong, Jiaoxuan, He, Songbin, Dai, Fangyu, etc.
在线发表的中国舟山群岛横断面研究，分析了农民工与当地居民缺血性卒中的流行病学模式及临床特征差异。舟山群岛作为城市化群岛，农民工群体心血管疾病风险受关注，本研究旨在明确其缺血性卒中特点。
研究纳入1006例缺血性卒中患者，其中452例为农民工，554例为当地居民。团队收集临床及影像学数据，采用t检验/非参数检验、卡方检验、二元logistic回归等方法对比两组患者特征，统计显著性设定为P<0.05。
结果显示，与当地居民相比，农民工患者体重指数更高，超重/肥胖比例显著升高；糖尿病和房颤发病率更低。实验室指标中，农民工淋巴细胞、尿酸、叶酸及维生素B12水平更低。影像学方面，两组病因分类无差异，但农民工基底节梗死发生率更高（P<0.05）。
结论指出，农民工缺血性卒中临床特征与当地居民不同，表现为更高BMI、超重/肥胖比例及基底节梗死发生率，更低糖尿病和房颤发病率。提示城市化群岛环境中需针对农民工开展针对性预防性医疗干预。
本文由 韩玉莲 编辑
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Neuroepidemiology | Ahead of Print.
10.1159/000551939
03 Frontiers in endocrinology IF: 04.600 温度和湿度对糖尿病患者舌色的依赖型交互作用：定量分析及中医视角
Zhang, Bingnan, Zhang, Naijin, Ren, Huixia, Li, Yonghui, Du, Haiyan, Ren, Tingjing, etc.
本研究通过对1711名糖尿病患者的多中心回顾性研究，首次量化验证了温度和相对湿度（以11月-次年4月为冷季、5-10月为热季） 对舌色的影响。
研究将参与者分为无糖尿病、单纯糖尿病、糖尿病合并高血压、糖尿病合并冠心病、糖尿病合并高血压和冠心病五组，采用TFDA-1舌诊仪采集舌色RGB数据（5个部位×3色，共30个指标），并通过多元线性回归分析发现：糖尿病患者舌色与温湿度存在显著交互作用，其中糖尿病合并高血压和冠心病的患者在高温高湿季节（7-8月） 舌色显著变红（P<0.0001），而无糖尿病组全年舌色稳定。
进一步主成分分析显示，舌体中部R值 对温湿度最敏感，且与并发症数量呈剂量反应关系（P<0.05）。
这些结果为中医“天人相应”理论提供了现代科学支持，提示舌色可作为高温高湿环境下糖尿病心血管代谢风险的动态生物标志物。
本文由 韩玉莲 编辑
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Frontiers in endocrinology | Volume 17, Issue
10.3389/fendo.2026.1772207
中国发表（84）
China
Chin J Integr Med IF: 02.500Ahead of Print.No.01Mechanisms of Tianma Gouteng Yin in Treating Hypertension-Associated Vascular Cognitive Impairment: Insights from Experiments, Network Pharmacology, and Molecular Docking天麻钩藤饮治疗高血压相关血管性认知障碍的机制：实验、网络药理学和分子对接的见解DOI: 10.1007/s11655-026-4039-6
Placenta IF: 02.500Ahead of Print.No.02The dynamic interplay between insulin resistance and autophagy: Exploring the coordinated regulation of multiple pathways in the pathogenesis of miscarriage胰岛素抵抗与自噬的动态相互作用：探索流产发病机制中多条通路的协同调控DOI: 10.1016/j.placenta.2026.03.015
IF: 03.700Ahead of Print.No.03Perilipin 5 enhances glycogen storage and mitigates excessive fatty acid oxidation in skeletal muscle to alleviate mitochondrial impairment脂滴包被蛋白5增强骨骼肌糖原储存并减轻过度脂肪酸氧化以缓解线粒体损伤DOI: 10.1016/j.bbamcr.2026.120146
Tissue & cell IF: 02.500Ahead of Print.No.04Antagonism of GPR75 inhibits gestational diabetes mellitus-induced placental tissue injury by preventing activation of the NLRP3 inflammasomeGPR75拮抗剂通过抑制NLRP3炎性小体激活减轻妊娠期糖尿病诱导的胎盘组织损伤DOI: 10.1016/j.tice.2026.103515
Stem cell research & therapy IF: 07.300Ahead of Print.No.05Apoptotic BMSCs reduce grafted islets apoptosis through the holo-Lcn2/Slc22a17/Fe(3+) axis凋亡骨髓间充质干细胞通过holo-Lcn2/Slc22a17/Fe(3+)轴减少移植胰岛的凋亡DOI: 10.1186/s13287-026-05001-9
Diabetes & metabolism IF: 04.700Ahead of Print.No.06BMD: Toward mechanistically-informed and fracture-specific treatment thresholds in diabetic bone disease骨密度：糖尿病性骨病中基于机制和特定骨折类型的治疗阈值DOI: 10.1016/j.diabet.2026.101759
Mol Cell Endocrinol IF: 03.600Ahead of Print.No.07Glucose deprivation impairs lipid tolerance related to mitophagy disorder in cardiomyocytes葡萄糖剥夺损害与心肌细胞线粒体自噬紊乱相关的脂质耐受性DOI: 10.1016/j.mce.2026.112804
Int J Biol Macromol IF: 08.500Ahead of Print.No.08Preparation and performance regulations of ionic cellulose-based glucose semipermeable membranes离子纤维素基葡萄糖半透膜的制备及性能调控DOI: 10.1016/j.ijbiomac.2026.151926
Free radical biology & medicine IF: 08.200Ahead of Print.No.09Echinacoside Improves Antioxidant Responses and Angiogenesis Through Parkin-MFN2-Mediated Mitophagy to Promote Diabetic Wound Healing松果菊苷通过Parkin-MFN2介导的线粒体自噬改善抗氧化反应和血管生成以促进糖尿病创面愈合DOI: 10.1016/j.freeradbiomed.2026.04.012
Brain research bulletin IF: 03.700Ahead of Print.No.10Plasma Exosomal Proteomics: Unveiling Novel Biomarkers for Ischemic Stroke in the Context of Diabetes血浆外泌体蛋白质组学：在糖尿病背景下揭示缺血性卒中的新生物标志物DOI: 10.1016/j.brainresbull.2026.111884
Biomedical materials IF: 03.700Ahead of Print.No.11Multifunctional eutectogel for co-delivery of baicalein and metformin to promote diabetic wound healing多功能共晶凝胶用于黄芩素和二甲双胍的共递送以促进糖尿病伤口愈合DOI: 10.1088/1748-605X/ae5e13
Biochem Biophys Res Commun IF: 02.200Ahead of Print.No.12Role of the NF-κB signaling pathway in vascular endothelial cell injury associated with metabolic dysfunction-associated steatotic liver disease under hypoxia缺氧条件下代谢功能障碍相关脂肪性肝病（MASLD）中NF-κB信号通路在血管内皮细胞损伤中的作用DOI: 10.1016/j.bbrc.2026.153710
BMC ophthalmology IF: 01.700Ahead of Print.No.13Effects of anti-VEGF therapy on choroidal thickness in eyes with diabetic macular edema抗VEGF治疗对糖尿病黄斑水肿患者眼脉络膜厚度的影响DOI: 10.1186/s12886-026-04811-y
J Ocul Pharmacol Ther IF: 02.100Ahead of Print.No.14SDF-1 Inhibition Attenuates VEGF-Driven Retinal Leukostasis and Neovascularization in Ischemic RetinopathySDF-1抑制减轻缺血性视网膜病变中VEGF驱动的视网膜白细胞滞留和新生血管形成DOI: 10.1177/10807683261441054
Acta pharmaceutica IF: 01.400Ahead of Print.No.15Pelargonidin protects retinal ganglion cells in a streptozotocin-induced diabetic rat model by reducing intraocular pressure, suppressing TGF-β and activating JAK2/STAT3 signalling pathway天竺葵素通过降低眼内压、抑制TGF-β并激活JAK2/STAT3信号通路在链脲佐菌素诱导的糖尿病大鼠模型中保护视网膜神经节细胞DOI: 10.2478/acph-2026-0010
Lipids in health and disease IF: 04.200Ahead of Print.No.16Comparative effects of central adiposity and BMI trajectories on cardiometabolic diseases in Chinese adults: a longitudinal cohort study中国成年人中心性肥胖与BMI轨迹对心血管代谢疾病的比较影响：一项纵向队列研究DOI: 10.1186/s12944-026-02948-9
Lipids in health and disease IF: 04.200Ahead of Print.No.17Assessment of BMI percentages of obesity thresholds and cardiometabolic risk factors in children and adolescents: a retrospective cross-sectional study in Beijing北京儿童青少年肥胖阈值BMI百分比及心血管代谢危险因素评估：一项回顾性横断面研究DOI: 10.1186/s12944-026-02940-3
BMC pediatrics IF: 02.000Ahead of Print.No.18Association between low-carbohydrate diet score and childhood obesity: a national population-based study低碳水化合物饮食评分与儿童肥胖的关联：一项全国性人群研究DOI: 10.1186/s12887-026-06835-1
BMC geriatrics IF: 03.800Ahead of Print.No.19Sarcopenic obesity definitions and their association with cardiovascular disease and mortality肌少症肥胖的定义及其与心血管疾病和死亡率的关联DOI: 10.1186/s12877-026-07433-7
Nature communications IF: 15.700Ahead of Print.No.20Leucine catabolic enzyme AUH regulates BAT thermogenesis via PPARγ HMGylation and RNA-binding function in male mice亮氨酸分解代谢酶AUH通过PPARγ的HMG化修饰和RNA结合功能调控雄性小鼠棕色脂肪组织产热DOI: 10.1038/s41467-026-71581-y
Int J Oral Sci IF: 12.200Volume 18, Issue 1No.21The structure and function of taste G protein-coupled receptors and their implications in diseases味觉G蛋白偶联受体的结构、功能及其在疾病中的意义DOI: 10.1038/s41368-026-00436-5
J Int Med Res IF: 01.500Volume 54, Issue 4No.22Association between cardiometabolic index and high-sensitivity C-reactive protein: A cross-sectional study from National Health and Nutrition Examination Survey 2015 to 2018心脏代谢指数与高敏C反应蛋白的关联：基于2015-2018年美国国家健康与营养检查调查的横断面研究DOI: 10.1177/03000605261436654
Environmental pollution IF: 07.300Ahead of Print.No.23Gender-Specific Association between Household Cooking Oil Fume exposure and Small Airway Dysfunction in China: a national cross-sectional study中国家庭烹饪油烟暴露与小气道功能障碍的性别特异性关联：一项全国性横断面研究DOI: 10.1016/j.envpol.2026.128094
IF: 03.700Ahead of Print.No.24FTO-mediated m6A demethylation inhibits bladder cancer progression via decreasing EMG1 and reducing ribosome biosynthesisFTO介导的m6A去甲基化通过降低EMG1和减少核糖体生物合成抑制膀胱癌进展DOI: 10.1016/j.bbamcr.2026.120147
JCTS IF: 01.500Ahead of Print.No.25de Winter-like anterior electrocardiographic changes coexisting with inferior ST-elevation myocardial infarction: a case report and literature insight类似De Winter型前壁心电图改变并存下壁ST段抬高型心肌梗死：病例报告及文献解读DOI: 10.1186/s13019-026-04031-x
BMC pregnancy and childbirth IF: 02.700Ahead of Print.No.26Association between maternal thyroid function and adverse outcomes of pregnant women and offspring: evidence from an umbrella review孕妇甲状腺功能与孕妇及后代不良结局的关联：来自总览综述的证据DOI: 10.1186/s12884-026-09024-1
Phytomedicine IF: 08.300Ahead of Print.No.27Amygdalin alleviates MAFLD via inhibiting cytoplasmic calcium ion overload-induced liver sinusoidal endothelial cell defenestration苦杏仁苷通过抑制细胞质钙离子超载诱导的肝血窦内皮细胞窗孔缺失来缓解代谢功能障碍相关脂肪性肝病DOI: 10.1016/j.phymed.2026.158135
Food chemistry IF: 09.800Ahead of Print.No.28Deciphering the molecular mechanism of DPP-IV inhibition by quinoa-derived peptides: Insights from kinetics, spectroscopy, and in silico perspectives破译藜麦来源肽对DPP-IV抑制的分子机制：来自动力学、光谱学和计算机模拟视角的见解DOI: 10.1016/j.foodchem.2026.149169
Phytomedicine IF: 08.300Ahead of Print.No.29Integrated analysis of network pharmacology and multi-omics reveals the mechanisms of Zuogui Jiangtang Qinggan formula ameliorates MASLD via fatty acid metabolic reprogramming网络药理学与多组学整合分析揭示左归丸降糖清肝方通过脂肪酸代谢重编程改善代谢功能障碍相关脂肪性肝病的机制DOI: 10.1016/j.phymed.2026.158128
Medicine IF: 01.400Volume 105, Issue 15No.30Visceral adipose tissue and risk of kidney stones: Evidence from NHANES 2011-2018 and Mendelian randomization analysis内脏脂肪组织与肾结石风险：来自NHANES 2011-2018的数据及孟德尔随机化分析的证据DOI: 10.1097/MD.0000000000048216
Medicine IF: 01.400Volume 105, Issue 15No.31Body fat percentage and hypertension risk: A population-based observational and Mendelian randomization study体脂率与高血压风险：一项基于人群的观察性及孟德尔随机化研究DOI: 10.1097/MD.0000000000048262
Medicine IF: 01.400Volume 105, Issue 15No.32The potential of 8 insulin resistance indicators as biomarkers for predicting gallstone risk in American adults: A cross-sectional NHANES study8种胰岛素抵抗指标作为美国成年人胆结石风险预测生物标志物的潜力：一项横断面NHANES研究DOI: 10.1097/MD.0000000000048229
Medicine IF: 01.400Volume 105, Issue 15No.33Celiac disease increases the risk of pulmonary arterial hypertension: A multivariable Mendelian randomization and mediation analysis乳糜泻增加肺动脉高压风险：一项多变量孟德尔随机化与中介分析DOI: 10.1097/MD.0000000000048334
Medicine IF: 01.400Volume 105, Issue 15No.34Association between urinary cadmium exposure and metabolic syndrome and the mediating role of thyroid dysfunction: NHANES 2007 to 2012尿镉暴露与代谢综合征的关联及甲状腺功能障碍的中介作用：2007-2012年NHANES研究DOI: 10.1097/MD.0000000000048230
Medicine IF: 01.400Volume 105, Issue 15No.35Diabetes, obesity, hyperlipidemia, and sudden sensorineural hearing loss: A bidirectional and multivariable Mendelian randomization study糖尿病、肥胖、高脂血症与突发性感音神经性听力损失：一项双向多变量孟德尔随机化研究DOI: 10.1097/MD.0000000000048255
Medicine IF: 01.400Volume 105, Issue 15No.36Nicotine metabolite ratio and clinically significant depressive symptoms in U.S. adults: A smoker-specific association美国成年人的尼古丁代谢物比率与具有临床意义的抑郁症状：吸烟者特异性关联研究DOI: 10.1097/MD.0000000000048186
Medicine IF: 01.400Volume 105, Issue 15No.37Urinary bladder obstruction caused by fungal balls: Unusual computed tomography findings - a case report真菌球导致的膀胱梗阻：不寻常的CT表现——病例报告DOI: 10.1097/MD.0000000000048244
Medicine IF: 01.400Volume 105, Issue 15No.38Association between serum dehydroepiandrosterone sulfate and type 2 diabetes in US adults with adiposity as a mediator血清脱氢表雄酮硫酸盐与美国成年人2型糖尿病的关联（以肥胖为中介）DOI: 10.1097/MD.0000000000048280
Medicine IF: 01.400Volume 105, Issue 15No.39Association between the endothelial activation and stress index and cardiometabolic multimorbidity: Results from the NHANES 2003 to 2020内皮激活和应激指数与心脏代谢共病的关联：来自美国国家健康与营养检查调查2003-2020的结果DOI: 10.1097/MD.0000000000048226
Journal of robotic surgery IF: 03.000Volume 20, Issue 1No.40Robotic versus laparoscopic surgery for rectal cancer in overweight and obese patients: pathological outcomes, complications, and trial sequential analysis超重和肥胖患者直肠癌的机器人手术与腹腔镜手术：病理结果、并发症及试验序贯分析DOI: 10.1007/s11701-026-03394-6
Singapore Medical Journal IF: 01.900Ahead of Print.No.41Metabolic dysfunction-associated steatotic liver disease in Asia: implications on management亚洲代谢功能障碍相关脂肪性肝病：对管理的影响DOI: 10.4103/singaporemedj.SMJ-2025-167
J Mol Neurosci IF: 02.700Volume 76, Issue 2No.42Clinical Study on the Combined Use of Tadalafil and Epalrestat in the Treatment of Diabetic Neurovascular Erectile Dysfunction他达拉非与依帕司他联合使用治疗糖尿病神经血管性勃起功能障碍的临床研究DOI: 10.1007/s12031-026-02504-1
The FASEB journal : IF: 04.200Volume 40, Issue 8No.43BGP-15 Mitigates Oxidative Stress and Mitochondrial Dysfunction in In Vitro Matured Oocytes From Type 1 Diabetic MiceBGP-15缓解1型糖尿病小鼠体外成熟卵母细胞中的氧化应激和线粒体功能障碍DOI: 10.1096/fj.202505013RR
Ophthalmology and therapy IF: 03.200Ahead of Print.No.44Efficacy, Durability, and Safety of Faricimab for Diabetic Macular Edema: 1-Year Results from the China RHINE SubpopulationFaricimab治疗糖尿病黄斑水肿的有效性、持久性及安全性：中国RHINE亚组的1年结果DOI: 10.1007/s40123-026-01378-1
J Bioenerg Biomembr IF: 03.000Volume 58, Issue 1No.45USF1 transcriptionally activates TRIM55 to promote diabetic cardiomyopathy progression by enhancing HSPB1 protein degradationUSF1通过转录激活TRIM55促进糖尿病心肌病进展（增强HSPB1蛋白降解）DOI: 10.1007/s10863-026-10107-z
The FASEB journal : IF: 04.200Volume 40, Issue 8No.46CTNNB1 Genetic Variation and Its Interaction With DLK1 in Type 2 Diabetes MellitusCTNNB1基因变异及其与DLK1在2型糖尿病中的相互作用DOI: 10.1096/fj.202600107R
Renal failure IF: 03.000Volume 48, Issue 1No.47Resveratrol inhibits renal ischemia and reperfusion injury in diabetes via reducing oxidative stress, inflammation, and apoptosis白藜芦醇通过降低氧化应激、炎症和凋亡抑制糖尿病肾缺血再灌注损伤DOI: 10.1080/0886022X.2026.2652103
JCBFM IF: 04.500Ahead of Print.No.48Cerebral small vessel disease burden relates to cognitive decline via impaired amyloid clearance in the general population普通人群中脑小血管病负担通过淀粉样蛋白清除受损与认知衰退相关DOI: 10.1177/0271678X261437577
Frontiers in public health IF: 03.400Volume 14, Issue No.49High rate of marginal vitamin A deficiency in children aged 0-6 years in Quanzhou, China: a cross-sectional study中国泉州0-6岁儿童维生素A边缘性缺乏高患病率：一项横断面研究DOI: 10.3389/fpubh.2026.1727761
Frontiers in nutrition IF: 05.100Volume 13, Issue No.50CT-assessed abdominal visceral adiposity and MASLD: a sex-stratified cross-sectional analysis性别分层及非线性分析：腹部脂肪分布与代谢功能障碍相关脂肪性肝病（MASLD）的关联DOI: 10.3389/fnut.2026.1750470
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.51The impact of bariatric surgery on male sexual function: a systematic review and meta-analysis减重手术对男性性功能的影响：一项系统综述与荟萃分析DOI: 10.3389/fendo.2026.1798050
Renal failure IF: 03.000Volume 48, Issue 1No.52Emerging roles of ATP citrate lyase in kidney diseases: from pathogenic driver to therapeutic target三磷酸腺苷柠檬酸裂合酶在肾脏疾病中的新兴作用：从致病驱动因素到治疗靶点DOI: 10.1080/0886022X.2026.2652826
J Health Popul Nutr IF: 02.800Ahead of Print.No.53Obesity, physical activity, and gene-environment interactions: a natural experiment framework肥胖、体力活动与基因-环境相互作用：一种自然实验框架DOI: 10.1186/s41043-026-01312-y
Frontiers in nutrition IF: 05.100Volume 13, Issue No.54Associations between lipid-derived indices and cardiovascular-kidney-metabolic syndrome progression among Chinese middle-aged and elderly adults: a longitudinal study脂质衍生指标与心血管-肾脏-代谢综合征患者心血管疾病风险的关系：一项回顾性队列研究DOI: 10.3389/fnut.2026.1742974
Frontiers in pediatrics IF: 02.000Volume 14, Issue No.55Risk factors for necrotizing enterocolitis in preterm infants: a 1:1 matched case-control study早产儿坏死性小肠结肠炎的危险因素：一项回顾性队列研究DOI: 10.3389/fped.2026.1807022
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.56The effect of continuous glucose monitoring on neonatal outcomes in pregnant women with diabetes合并糖尿病的妊娠中持续葡萄糖监测：随机对照试验的系统综述与荟萃分析DOI: 10.3389/fendo.2026.1815133
China CDC weekly IF: 02.900Volume 8, Issue 10No.57Association Between Longitudinal Serum Ferritin and Gestational Diabetes Mellitus - Beijing, Shanxi, and Shandong PLADs, China, 2021-2024中国人群中孕早期和孕中期血清铁蛋白与妊娠糖尿病的关联：一项多中心前瞻性队列研究DOI: 10.46234/ccdcw2026.044
BMC pregnancy and childbirth IF: 02.700Ahead of Print.No.58Association of mid-pregnancy remnant cholesterol levels with adverse pregnancy outcomes in women with gestational diabetes mellitus妊娠期糖尿病女性妊娠中期残余胆固醇水平与不良妊娠结局的关联DOI: 10.1186/s12884-026-09031-2
Journal of pregnancy IF: 02.200Volume 2026, Issue 1No.59A Qualitative Study on TPB-Based Factors for Breastfeeding Cessation in Women With Gestational Diabetes Mellitus in the Early Postpartum Period一项基于计划行为理论（TPB）的妊娠期糖尿病女性产后早期母乳喂养中断因素的定性研究DOI: 10.1155/jp/5369691
Front Cell Dev Biol IF: 04.300Volume 14, Issue No.60ChatGPT-5 versus other mainstream large language models in core diabetic retinopathy patient queries五种主流大语言模型在糖尿病视网膜病变健康教育和患者分诊中的比较分析DOI: 10.3389/fcell.2026.1754221
Materials today bio IF: 10.200Volume 38, Issue No.61Glucose modulates macrophage polarization via glycating adsorbed albumin on titanium葡萄糖通过钛表面糖化吸附白蛋白调节巨噬细胞极化DOI: 10.1016/j.mtbio.2026.103047
Frontiers in pharmacology IF: 04.800Volume 17, Issue No.62The influence of tranexamic acid on intraoperative blood transfusion in short-segment PLIF and analysis of influencing factors of the transfusion: a retrospective case study氨甲环酸减少短节段腰椎椎间孔融合术中失血和输血：一项回顾性研究DOI: 10.3389/fphar.2026.1736382
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.63Helicobacter pylori infection is independently associated with triglyceride levels: a propensity score-matched cross-sectional study幽门螺杆菌感染与甘油三酯水平独立相关：一项倾向评分匹配的横断面研究DOI: 10.3389/fendo.2026.1792530
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.64Prevalence, risk factors, and early prediction of cognitive impairment in patients with diabetes mellitus: a systematic review and meta-analysis糖尿病患者认知障碍的系统综述与荟萃分析DOI: 10.3389/fendo.2026.1757367
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.65Temperature and humidity-dependent interaction effects on tongue color in diabetic patients: a quantitative analysis and TCM perspective温度和湿度对糖尿病患者舌色的依赖型交互作用：定量分析及中医视角DOI: 10.3389/fendo.2026.1772207
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.66Efficacy and safety of different anti-VEGF agents combined with pars plana vitrectomy in proliferative diabetic retinopathy: a systematic review and network meta-analysis of randomized controlled trials抗血管内皮生长因子药物联合经扁平部玻璃体切割术治疗增殖性糖尿病视网膜病变的有效性和安全性：一项网络荟萃分析DOI: 10.3389/fendo.2026.1772351
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.67Cross-sectional analysis of the association between physical activity and metabolic syndrome in the elderly社区居住老年人中体力活动与代谢综合征的关联：一项横断面研究DOI: 10.3389/fendo.2026.1799367
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.68Real-world performance of open-source large language models in diabetes diagnosis临床糖尿病诊断中的开源大语言模型：亚分型、并发症及提示策略的综合评估DOI: 10.3389/fendo.2026.1747468
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.69Epigenetic dichotomy in florid vs. gliotic proliferative diabetic retinopathy: hypomethylation of EGLN1 and MMP9 drives divergent pathogenic pathways in angiogenesis and fibrosis增殖性糖尿病视网膜病变亚型（旺炽型vs纤维增生型）表观遗传特征的差异甲基化模式DOI: 10.3389/fendo.2026.1664104
Front Bioeng Biotechnol IF: 04.800Volume 14, Issue No.70Hydroxypropyl methylcellulose stearoxy ether hydrogel loaded with aloe vera peel-derived extracellular vesicle mimetics promotes wound healing in diabetic mice芦荟皮来源细胞外囊泡模拟物通过Sangeose 60L水凝胶递送促进糖尿病伤口愈合DOI: 10.3389/fbioe.2026.1768930
Ophthalmology science IF: 04.600Volume 6, Issue 5No.71Using OCT Angiography to Predict Diabetic Retinopathy Progression and Vision Decline in a Multiethnic CohortOCT血管造影预测糖尿病视网膜病变进展及视力下降的多中心研究DOI: 10.1016/j.xops.2026.101111
Frontiers in immunology IF: 05.900Volume 17, Issue No.72Recent advances in the positive role of Clostridium in autoimmune diseases: as a crucial regulator of restoring immune-metabolic equilibrium有益梭菌及其代谢物在自身免疫性疾病中的作用：综合综述DOI: 10.3389/fimmu.2026.1730351
Frontiers in medicine IF: 03.000Volume 13, Issue No.73Longitudinal associations between treatment adherence patterns and blood pressure control among rural hypertensive patients in Central China: a real-world retrospective cohort study现实世界基层医疗环境中血压控制的时间趋势及预测因素：一项纵向队列研究DOI: 10.3389/fmed.2026.1791265
Chemistry & biodiversity IF: 02.500Volume 23, Issue 4No.74Rapid Identification of Chemical Components and Prediction of Medicinal Value for Blachia Siamensis Leaves暹罗黑面神叶的化学成分快速鉴定及药用价值预测DOI: 10.1002/cbdv.202503300
Zhonghua Wei Zhong Bing Ji Jiu Yi XueVolume 38, Issue 3No.75[Predictive value of the modified Nutrition Risk in Critically Ill Score for intensive care unit mortality risk in septic patients]改良型重症患者营养风险评分（mNUTRIC）对脓毒症患者ICU死亡率风险的预测价值DOI: 10.3760/cma.j.cn121430-20250716-00390
Front Cell Dev Biol IF: 04.300Volume 14, Issue No.76MicroRNA, MicroRNA-lncRNA and MicroRNA-Circular RNA axes, and exosomal MicroRNAs: driving exercise-induced cardioprotection in heart failure运动诱导心脏保护中的非编码RNA：机制、生物标志物及治疗潜力DOI: 10.3389/fcell.2026.1767057
Current opinion in physiology IF: 01.900Volume 46, Issue No.77Caveolin in extracellular vesicles: orchestrating interorgan communication in diabetes-associated cardiovascular disease(☆)窝蛋白在小细胞囊泡中：调控糖尿病相关心血管疾病中的器官间通讯DOI: 10.1016/j.cophys.2025.100862
Journal of oral microbiology IF: 05.500Volume 18, Issue 1No.78Association between oral microbial shifts and polycystic ovary syndrome: a systematic review多囊卵巢综合征中的口腔微生物群失调：系统综述与荟萃分析DOI: 10.1080/20002297.2026.2650921
Frontiers in immunology IF: 05.900Volume 17, Issue No.79Role of Treg cells in diabetes mellitus and association with traditional Chinese medicine: a literature review调节性T细胞（Tregs）在糖尿病及其并发症中的作用：综述DOI: 10.3389/fimmu.2026.1763798
J Cell Mol Med IF: 04.200Volume 30, Issue 7No.80Exploration of the Potential Mechanism of Metal Ion Transport-Related Genes in Myocardial Infarction Based on Transcriptomics基于转录组学探索心肌梗死中金属离子转运相关基因的潜在机制DOI: 10.1111/jcmm.71134
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.81The diagnostic value of immune-inflammatory markers for diabetic kidney disease in type 2 diabetic patients: a meta-analysis2型糖尿病患者免疫炎症标志物对糖尿病肾病的诊断价值：一项荟萃分析DOI: 10.3389/fendo.2026.1811189
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Frontiers in endocrinology IF: 04.600Volume 17, Issue No.83Clinical efficacy of combining fenofibrate with statins in patients with diabetes and hyperlipidemia: a meta-analysis非诺贝特与他汀类药物联合治疗糖尿病合并高脂血症患者的Meta分析DOI: 10.3389/fendo.2026.1694928
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BMC medicine IF: 08.300Volume 24, Issue 1No.12Interventions to prevent and treat multiple long-term conditions and their consequences across the life course: concepts and definitions干预措施预防和治疗生命全程中的多种长期疾病及其后果：概念和定义DOI: 10.1186/s12916-026-04838-4
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J Expo Sci Environ Epidemiol IF: 04.700Ahead of Print.No.17Bisphenol S and female reproductive toxicity: a scoping review of human studies双酚S与女性生殖毒性：人类研究的范围综述DOI: 10.1038/s41370-026-00868-5
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Scientific reports IF: 03.900Ahead of Print.No.19Comparison of biochemical oxidative stress markers of glucose tolerance tests performed for葡萄糖耐量试验的生化氧化应激标志物比较DOI: 10.1038/s41598-026-45946-8
Nature communications IF: 15.700Ahead of Print.No.20Pervasive non-triplet alternative splicing drives functional isoform diversity普遍的非三联体选择性剪接驱动功能性异构体多样性DOI: 10.1038/s41467-026-71615-5
Nature communications IF: 15.700Volume 17, Issue 1No.21Exposome-wide patterns predict brain health in aging全暴露组模式预测衰老中的大脑健康DOI: 10.1038/s41467-026-71271-9
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BMC medicine IF: 08.300Volume 24, Issue 1No.35Why hyperinsulinemia is detrimental to weight loss: insights from type 1 diabetes高胰岛素血症为何不利于减肥：来自1型糖尿病的见解DOI: 10.1186/s12916-026-04849-1
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J Laparoendosc Adv Surg Tech A IF: 01.100Ahead of Print.No.37Hiatal Hernia Following a Sleeve Gastrectomy袖状胃切除术后的食管裂孔疝DOI: 10.1177/10926429261420529
Surg Obes Relat Dis IF: 03.800Ahead of Print.No.38International expert consensus on definitions and management of weight recurrence and suboptimal response after metabolic and bariatric surgery: a Delphi study国际专家共识：代谢与减重手术后体重复发及反应不佳的定义与管理——一项德尔菲研究DOI: 10.1016/j.soard.2026.03.006
Sleep health IF: 03.400Ahead of Print.No.39Objective prediction of siesta based on machine learning and association with obesity基于机器学习的午睡客观预测及其与肥胖的关联DOI: 10.1016/j.sleh.2026.02.007
Advances in wound care IF: 05.600Ahead of Print.No.40Metabolic Effects on Wound Healing代谢对伤口愈合的影响DOI: 10.1177/21621918261438987
BMJ case reports IF: 00.500Volume 19, Issue 4No.41Awake video laryngoscopy and tracheal intubation in a super morbidly obese critically ill patient with a physiologically difficult airway清醒视频喉镜检查与气管插管在超级病态肥胖重症患者（伴生理困难气道）中的应用DOI: 10.1136/bcr-2025-269211
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Journal of nutrition IF: 03.800Ahead of Print.No.43Quadruple burden of young child malnutrition in the Children's Healthy Living program, US Affiliated Pacific美国附属太平洋地区儿童健康生活计划中幼儿营养不良的四重负担DOI: 10.1016/j.tjnut.2026.101527
Neuroscience letters IF: 02.000Ahead of Print.No.44The exposure to the air pollutant fine particulate matter (PM(2.5)) slightly enhances high-fat diet-induced anxiety-like behavior and impairs brain redox balance in female rats空气污染物细颗粒物(PM2.5)暴露略微增强高脂饮食诱导的雌性大鼠焦虑样行为并损害脑氧化还原平衡DOI: 10.1016/j.neulet.2026.138599
J Am Pharm Assoc (2003)Ahead of Print.No.45Real-world weight impact upon tirzepatide discontinuation at a single-center endocrinology clinic in patients with overweight or obesity单中心内分泌诊所中超重或肥胖患者停用替尔泊肽后的真实体重影响DOI: 10.1016/j.japh.2026.103112
Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.46Indirect relationship between alexithymia and binge eating disorder in the context of obesity肥胖背景下述情障碍与暴饮暴食障碍的间接关系DOI: 10.1016/j.clnesp.2026.103274
Brain research bulletin IF: 03.700Ahead of Print.No.47Exposure to a High-Fat Diet Compromises Gut Health, Behavior, and HPA Axis Function, with Partial Reversal When Limited to Adolescence暴露于高脂饮食会损害肠道健康、行为和HPA轴功能，青春期限制暴露后部分逆转DOI: 10.1016/j.brainresbull.2026.111883
The American journal of surgery IF: 02.700Ahead of Print.No.48Patient perspectives on access to bariatric surgical care in the Deep South: A qualitative study美国南部地区患者获取减重手术护理的观点：一项定性研究DOI: 10.1016/j.amjsurg.2026.116973
Nutrition IF: 03.000Ahead of Print.No.49The effect of ultra-processed food reduction in an attempt to control abdominal pain after Roux-Y gastric bypass: A retrospective cohort study减少超加工食品以控制Roux-Y胃旁路术后腹痛的效果：一项回顾性队列研究DOI: 10.1016/j.nut.2026.113182
Atención primaria IF: 01.600Ahead of Print.No.50[Anti-obesity drugs and potential changes in the epidemiology of this condition and in cardiovascular risk factors]抗肥胖药物及该疾病流行病学和心血管危险因素的潜在变化DOI: 10.1016/j.aprim.2026.103496
Chemosphere IF: 08.100Ahead of Print.No.51Exposure to lead on children's intellectual functioning: A target trial with multimedia biomarkers in Mexico City儿童智力功能的铅暴露：墨西哥城采用多介质生物标志物的目标试验DOI: 10.1016/j.chemosphere.2026.144932
BMJ case reports IF: 00.500Volume 19, Issue 4No.52Leydig cell ovarian tumour: a rare cause of hyperandrogenism卵巢间质细胞瘤：高雄激素血症的罕见原因DOI: 10.1136/bcr-2025-268251
Clin Exp Nephrol IF: 01.700Ahead of Print.No.53Effects of individual sodium-glucose cotransporter-2 inhibitors on all-cause mortality in patients with diabetic kidney disease个体化钠-葡萄糖协同转运蛋白2抑制剂对糖尿病肾病患者全因死亡率的影响DOI: 10.1007/s10157-026-02865-2
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Heart IF: 04.400Ahead of Print.No.55Risk factor profiles and haemodynamic progression in aortic stenosis: a retrospective population-based study主动脉瓣狭窄的危险因素概况与血流动力学进展：一项回顾性人群研究DOI: 10.1136/heartjnl-2025-327243
Endocrine practice IF: 04.600Ahead of Print.No.56Cardiovascular Effects of Alogliptin, Linagliptin, Saxagliptin, and Sitagliptin: A Target Trial Emulation of a Comparative Effectiveness Study阿格列汀、利格列汀、沙格列汀和西格列汀的心血管影响：一项比较有效性研究的目标试验模拟DOI: 10.1016/j.eprac.2026.04.004
Contemporary clinical trials IF: 01.900Volume 164, Issue No.57Promoting sustained behavior change and nutrition security in medicaid-enrolled individuals with stage 2 cardiovascular kidney metabolic syndrome (CKMS): Protocol of the SUSTAIN study促进获得医疗补助的患有2期心血管-肾脏-代谢综合征（CKMS）个体的持续行为改变和营养安全：SUSTAIN研究方案DOI: 10.1016/j.cct.2026.108285
Hypertension Research IF: 04.600Ahead of Print.No.58The effects of glucagon-like peptide-1 receptor agonists on sympathetic neuron activity胰高血糖素样肽-1受体激动剂对交感神经元活动的影响DOI: 10.1038/s41440-026-02633-5
Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.59The Impact of Malnutrition and Probable Sarcopenia on Mortality in Older Patients with Type 2 Diabetes营养不良和可能的肌少症对老年2型糖尿病患者死亡率的影响DOI: 10.1016/j.clnesp.2026.103273
Scientific reports IF: 03.900Ahead of Print.No.60Metabolic determinants of torque teno virus load across the diabetes spectrum: insights from a cross-sectional analysis跨糖尿病谱的转矩骨病毒载量的代谢决定因素：来自横断面分析的见解DOI: 10.1038/s41598-026-47810-1
Obes Res Clin Pract IF: 02.300Ahead of Print.No.61Bariatric surgery reverses blunted blood pressure reactivity to cold-induced stress in patients with severe obesity减重手术逆转严重肥胖患者对冷诱导应激的血压反应迟钝DOI: 10.1016/j.orcp.2026.03.005
Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.62TRIGLYCERIDE-RELATED LIPID CHANGES IN ADULTS WITH CYSTIC FIBROSIS TREATED WITH ELEXACAFTOR/TEZACAFTOR/IVACAFTOR: A REAL-WORLD CROSS-SECTIONAL STUDY使用依伐卡托/泰泽卡托/依伐卡托治疗的囊性纤维化成人患者的甘油三酯相关脂质变化：一项真实世界横断面研究DOI: 10.1016/j.clnesp.2026.103275
Arch Gerontol Geriatr IF: 03.800Ahead of Print.No.63Efficacy of telephone-based health counseling with wearable device-Smartphone monitoring in older adults with metabolic syndrome: A randomized controlled trial基于可穿戴设备（智能手机监测）的电话健康咨询对代谢综合征老年患者的有效性：一项随机对照试验DOI: 10.1016/j.archger.2026.106232
Pediatric neurology IF: 02.100Ahead of Print.No.64Caring for Gender Diverse Youth With Duchenne Muscular Dystrophy: A Multisite Case Series关怀性别多样化杜氏肌营养不良症青年：多中心病例系列研究DOI: 10.1016/j.pediatrneurol.2026.03.018
EClinicalMedicine IF: 10.000Ahead of Print.No.65Weight trajectories and obesity onset between 17 and 60 years of age, and cause-specific mortality: the Obesity and Disease Development Sweden (ODDS) pooled cohort study成年男性和女性的体重增加轨迹与死亡率：ODDS队列研究DOI: 10.1016/j.eclinm.2026.103870
Int Arch Allergy Immunol IF: 01.800Ahead of Print.No.66Bioinformatics Analysis and Animal Experiments Revealed the Potential Role of IGFBP3 in Allergic Rhinitis生物信息学分析和动物实验揭示IGFBP3在过敏性鼻炎中的潜在作用DOI: 10.1159/000551921
Journal of medicinal food IF: 02.000Ahead of Print.No.67Coffee Berry Pulp Extract Improves Hepatic Lipid Metabolism and Reduces Triglyceride Levels in High-Fat, High-Fructose Diet-Fed Mice咖啡浆果提取物改善高脂高果糖饮食喂养小鼠的肝脏脂质代谢并降低甘油三酯水平DOI: 10.1177/1096620X261441411
Dermatology IF: 02.700Ahead of Print.No.68Efficacy of Gabapentin Combined with Standard-dose Antihistamines versus Antihistamine Monotherapy in Prurigo Nodularis: A Prospective Monocentric Real-world Observational Study加巴喷丁联合标准剂量抗组胺药与抗组胺药单药治疗结节性痒疹的有效性：一项前瞻性单中心真实世界观察性研究DOI: 10.1159/000551865
PloS one IF: 02.600Volume 21, Issue 4No.69Examining the mediating effects of metabolic syndrome components on the relationship between dairy product consumption and nonalcoholic fatty liver disease in Korean adults韩国成年人中代谢综合征组分对乳制品摄入与非酒精性脂肪肝关系的中介作用研究DOI: 10.1371/journal.pone.0346774
J Neurosurg Pediatr IF: 02.100Ahead of Print.No.70Endoscopic disconnection of hypothalamic hamartoma: an already outdated story?内镜下下丘脑错构瘤切断术：是否已过时？DOI: 10.3171/2025.11.PEDS25377
Wiadomo?ci LekarskieVolume 79, Issue 3No.71The gut-brain axis and its role in obesity-induced homeostatic dysregulation肠脑轴及其在肥胖诱导的体内平衡失调中的作用DOI: 10.36740/WLek/218289
Wiadomo?ci LekarskieVolume 79, Issue 3No.72Body mass index as a determinant of surgical outcomes in total hip arthroplasty体重指数作为全髋关节置换术手术结果的决定因素DOI: 10.36740/WLek/218174
Hepatology : IF: 15.800Ahead of Print.No.73Genetic risk of steatotic liver disease: Pathogenesis, prognosis, and implications for treatment脂肪性肝病的遗传风险：发病机制、预后及治疗意义DOI: 10.1097/HEP.0000000000001758
JMIR formative research IF: 02.100Volume 10, Issue No.74Evaluating an Incentive-Based mHealth App for Physical Activity Promotion Using the Obesity-Related Behavioral Intervention Trial Model: Small Cohort Study基于激励的移动健康应用促进体力活动：使用与肥胖相关的行为干预试验模型的小队列研究DOI: 10.2196/85484
J Paediatr Child Health IF: 01.400Ahead of Print.No.75Effects of Probiotic and Synbiotic Supplementation on Metabolic and Hepatic Outcomes in Children and Adolescents With Obesity, Including Those With Obesity-Related Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis益生菌和益生元补充剂对患有肥胖症（包括患有与肥胖相关的代谢功能障碍相关脂肪性肝病的儿童和青少年）的代谢和肝脏结局的影响：一项系统综述和荟萃分析DOI: 10.1111/jpc.70344
PloS one IF: 02.600Volume 21, Issue 4No.76Association of visceral fat and plasmacytoid dendritic cell-derived interferon alpha with SARS-CoV-2 infection内脏脂肪与浆细胞样树突状细胞衍生的干扰素α和SARS-CoV-2感染的关联DOI: 10.1371/journal.pone.0344870
PLOS global public health IF: 02.500Volume 6, Issue 4No.77Prevalence and factors associated with obesity in Rwanda: Evidence from the 2022 NCD STEPS Survey卢旺达肥胖患病率及相关因素：来自2022年非传染性疾病阶梯式调查的证据DOI: 10.1371/journal.pgph.0004736
Respiration IF: 03.800Ahead of Print.No.78Sex comparison in clinical presentation, response, and remission in severe type-2 asthma patients treated with biologics: a real-world analysis from the "Southern Italy Network on Severe Asthma Therapy"生物制剂治疗重度2型哮喘患者的临床表型、反应和缓解情况的性别差异：来自“意大利南部重度哮喘治疗网络”的真实世界分析DOI: 10.1159/000550911
Respiration IF: 03.800Ahead of Print.No.79Paediatric long-term home respiratory support: Recommendations of the Swiss Society of Paediatric Pulmonology儿科长期家庭呼吸支持：瑞士儿科肺科学会的建议DOI: 10.1159/000550985
American journal of nephrology IF: 03.200Ahead of Print.No.80Potentially modifiable factors associated with longitudinal health-related quality of life in the National Unified Renal Translational Research Enterprise CKD (NURTuRE-CKD) cohort国家统一肾脏转化研究企业慢性肾脏病（NURTuRE-CKD）队列中与纵向健康相关生活质量相关的潜在可调节因素DOI: 10.1159/000551177
Medicina IF: 00.600Volume 86, Issue 2No.81[REMI-ICAR: Argentine multicenter registry of hospitalization due to heart failure in medical clinic services]REMI-ICAR：阿根廷内科门诊心力衰竭住院患者多中心登记研究https://pubmed.ncbi.nlm.nih.gov/41961598
Journal of neurosurgery. Spine IF: 03.100Ahead of Print.No.82Diabetes as a significant risk factor for postoperative dysphagia following cervical spine surgery糖尿病是颈椎手术后吞咽困难的重要危险因素DOI: 10.3171/2025.11.SPINE25838
Wiadomo?ci LekarskieVolume 79, Issue 3No.83Obesity as an interdisciplinary medical and social problem: Therapeutic opportunities肥胖作为一个跨学科的医学和社会问题：治疗机会DOI: 10.36740/WLek/218280
Wiadomo?ci LekarskieVolume 79, Issue 3No.84Lifestyle, diet, and physical activity in the prevention and rehabilitation of chronic diseases: A review生活方式、饮食和体力活动在慢性病预防与康复中的作用：综述DOI: 10.36740/WLek/217892
Wiadomo?ci LekarskieVolume 79, Issue 3No.85Clinico-epidemiological spectrum of constipation patients at a tertiary care center in Ajman, UAE - a descriptive 5 year data analysis阿联酋阿治曼某三级医疗中心便秘患者的临床流行病学特征——一项为期5年的描述性数据分析DOI: 10.36740/WLek/218273
Wiadomo?ci LekarskieVolume 79, Issue 3No.86Clinico-epidemiological spectrum of chronic liver disease patients at a tertiary care center in Ajman, UAE - a descriptive 5 year data analysis阿联酋阿治曼一家三级医疗机构慢性肝病患者的临床流行病学特征——5年描述性数据分析DOI: 10.36740/WLek/218412
Swiss Med WklyVolume 156, Issue No.87Effect of implementing measures to reduce resource utilisation in medical wards (CopAIN project): a single-centre interrupted time-series analysis实施减少医疗病房资源利用措施（CopAIN项目）的效果：一项单中心中断时间序列分析DOI: 10.57187/4539
Plast Reconstr Surg IF: 03.400Ahead of Print.No.88Mini Free Flaps for Diabetic Foot Reconstruction用于糖尿病足重建的小型游离皮瓣DOI: 10.1097/PRS.0000000000012628
The Journal of urology IF: 06.800Ahead of Print.No.89Generalized Sensory Sensitivity in Patients with Urinary Urgency - a LURN II Urinary Urgency Phenotyping Study尿急迫患者的广义感觉敏感性——LURN II尿急迫表型研究DOI: 10.1097/JU.0000000000005061
JBJS case connectorVolume 16, Issue 2No.90Differentiating Infective Bursitis and Prosthetic Joint Infection in a Patient With Medial Knee Pain After Total Knee Arthroplasty: A Case Report全膝关节置换术后内侧膝痛患者感染性滑囊炎与假体关节感染的鉴别：一例报告DOI: e25.00515
Science advances IF: 12.500Volume 12, Issue 15No.91Constitutive AMPK activation prevents hepatocellular carcinoma development through inhibition of HNF4α activity组成型AMPK激活通过抑制HNF4α活性预防肝细胞癌发展DOI: 10.1126/sciadv.aea8017
Crit Rev Clin Lab Sci IF: 05.500Ahead of Print.No.92Glycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease糖基化与疾病：晚期糖基化终产物（AGEs）作为疾病生物标志物的分析方法与应用系统综述DOI: 10.1080/10408363.2026.2651310
PloS one IF: 02.600Volume 21, Issue 4No.93Predicted meta-omics: A potential solution to multi-omics data scarcity in microbiome studies预测元组学：解决微生物组研究中多组学数据稀缺的潜在方案DOI: 10.1371/journal.pone.0345919
PloS one IF: 02.600Volume 21, Issue 4No.94Exploring barriers and enablers to diabetes self-care practice in Ethiopia, 2025: A qualitative systematic review埃塞俄比亚2025年糖尿病自我护理实践的障碍与促进因素：一项定性系统综述DOI: 10.1371/journal.pone.0346867
PloS one IF: 02.600Volume 21, Issue 4No.95WHO five moments for medication safety among diabetic patients in Saudi Arabia沙特阿拉伯糖尿病患者用药安全的WHO五时刻模型DOI: 10.1371/journal.pone.0346935
PloS one IF: 02.600Volume 21, Issue 4No.96Risk factors for spontaneous abortion following hepatitis E vaccination during and shortly before pregnancy: Further analysis from a cluster-randomized trial妊娠期间及孕前短期内接种戊型肝炎疫苗后自发性流产的危险因素：来自整群随机试验的进一步分析DOI: 10.1371/journal.pone.0345974
Kidney & Blood Pressure Research IF: 02.100Ahead of Print.No.97New Anticomplement Drugs in Nephrology - Mechanism and Indication肾脏病学中的新型抗补体药物——作用机制与适应症DOI: 10.1159/000551965
European thyroid journal IF: 04.300Ahead of Print.No.98Thyroid hormone therapy in a population cohort over two decades indicates persistent overtreatment二十年间人群队列中的甲状腺激素治疗表明持续过度治疗DOI: 10.1530/ETJ-25-0259
ESC Heart Failure IF: 03.700Ahead of Print.No.99An integrated Biobank in the Swedish Heart Failure Registry - clinomics, proteomics, transcriptomics and genomics瑞典心力衰竭登记处（SwedeHF）中的综合生物库——临床组学、蛋白质组学、转录组学和基因组学DOI: 10.1093/eschf/xvag092
Medicina IF: 00.600Volume 86, Issue 2No.100[Pulmonary cryptococcosis in a non-HIV patient]非HIV患者的肺隐球菌病https://pubmed.ncbi.nlm.nih.gov/41961617
EJHF IF: 10.800Ahead of Print.No.101Kidney Failure Risk Equation and Risk of Kidney and Cardiovascular Outcomes in Patients with Heart Failure with Reduced Ejection Fraction: Insights from PARADIGM-HF射血分数降低的心力衰竭患者的肾衰竭风险方程及肾脏和心血管结局风险：来自PARADIGM-HF研究的见解DOI: 10.1093/ejhf/xuag079
IEEE J Biomed Health Inform IF: 06.800Ahead of Print.No.102Lesion Learning Network with Relation Aware Transformer for Diabetic Retinopathy Grading带有关系感知Transformer的病变学习网络用于糖尿病视网膜病变分级DOI: 10.1109/JBHI.2026.3682783
Journal of neurosurgery IF: 03.600Ahead of Print.No.103Glucagon-like peptide-1 receptor agonists in patients with moyamoya disease and type 2 diabetes mellitus胰高血糖素样肽-1受体激动剂在烟雾病合并2型糖尿病患者中的应用DOI: 10.3171/2025.12.JNS251072
Reproduction & fertility IF: 03.400Ahead of Print.No.104Interconnection between Polycystic Ovary Syndrome, Immune Disorders, and Reproductive Outcomes多囊卵巢综合征、免疫失调与生殖结局的相互联系DOI: 10.1530/RAF-25-0186
The Lancet Digital Health IF: 24.100Ahead of Print.No.105ChatGPT for obesity management: a review of evidence, potential challenges, and clinical implicationsChatGPT在肥胖管理中的应用、挑战与未来方向综述DOI: 10.1016/j.landig.2026.100980
Fish physiology and biochemistry IF: 02.500Volume 52, Issue 2No.106Low temperatures impact on the expression of growth genes and miRNAs in Nile tilapia (Oreochromis niloticus)低温对尼罗罗非鱼生长基因和微小RNA表达的影响DOI: 10.1007/s10695-026-01679-z
Clin Hemorheol MicrocircAhead of Print.No.107A comprehensive review of GLP-1 and aerobic training in cardiovascular disease managementGLP-1和有氧运动在心血管疾病管理中的综合综述DOI: 10.1177/13860291251414840
International endodontic journal IF: 07.100Ahead of Print.No.108Foetal Development and Placental Health in Response to Apical Periodontitis Induced in Pregnant Wistar Rats妊娠Wistar大鼠诱导根尖周炎后胎儿发育及胎盘健康DOI: 10.1111/iej.70155
Sports medicine IF: 09.400Ahead of Print.No.109Instrumented Mouthguards in Women's Rugby League: Quantifying the Incidence and Probability of Head Acceleration Events at Group and Individual Levels女子橄榄球联盟中仪器化护齿套：量化群体和个体层面的头部加速事件发生率与概率DOI: 10.1007/s40279-026-02420-9
Molecular diversity IF: 03.800Ahead of Print.No.110Transdermal self-assembled Xanthine/hybrid needle nanofibers for management of abdominal obesity via phosphodiesterase 4B suppression经皮自组装黄嘌呤/杂化针状纳米纤维通过抑制磷酸二酯酶4B用于管理腹型肥胖DOI: 10.1007/s11030-026-11512-7
European journal of nutrition IF: 04.300Volume 65, Issue 3No.111The swift study: dietary profiles of night shift workers characterised by overweight and obesity快速研究：以超重和肥胖为特征的夜班工作者饮食特征DOI: 10.1007/s00394-026-03917-9
Indian journal of pediatrics IF: 02.000Ahead of Print.No.112Smartphone Applications-Based Intervention to Reduce Body Mass Index and Improve Health-Related Behavior Among Children with Overweight/Obesity: A Pilot Clinical Trial - Authors' Reply基于智能手机应用的干预措施降低超重/肥胖儿童体重指数并改善健康相关行为：一项试点临床试验——作者回复DOI: 10.1007/s12098-026-06117-9
Journal of robotic surgery IF: 03.000Volume 20, Issue 1No.113Trends and comparative study of robotic-assisted benign hysterectomy among morbidly obese patients in united States美国病态肥胖患者中机器人辅助良性子宫切除术的趋势与比较研究DOI: 10.1007/s11701-025-02991-1
Nutrición hospitalaria IF: 01.100Ahead of Print.No.114Longitudinal analysis of weight regain after Roux-en-Y gastric bypass ‒ The role of the MTCH2 gene polymorphism and dietary factorsRoux-en-Y减重手术后体重反弹的纵向分析——MTCH2基因多态性与饮食因素的作用DOI: 10.20960/nh.06238
Int J Gynaecol Obstet IF: 02.400Ahead of Print.No.115Influence of maternal body mass index on the accuracy of clinical and sonographic fetal weight estimation母体体重指数对临床和超声胎儿体重估计准确性的影响DOI: 10.1002/ijgo.71012
ANZ journal of surgery IF: 01.600Ahead of Print.No.116Re: How to Do an Emergency Robotic Hartmann's Procedure in a Morbidly Obese Patient如何在病态肥胖患者中进行紧急机器人哈特曼手术DOI: 10.1111/ans.70681
JAMA IF: 55.000Ahead of Print.No.117Triple Agonist Reduces Hemoglobin A1C and Weight in Patients With Type 2 Diabetes三重激动剂可降低2型糖尿病患者的糖化血红蛋白和体重DOI: 10.1001/jama.2026.2107
Mol Cell Pediatr IF: 03.400Volume 13, Issue 1No.118The conundrum in diagnosing Maturity-Onset Diabetes of the Young (MODY) in a large German pedigree with early-onset diabetes and a novel HNF1A variant在具有早发性糖尿病的大型德国家系中诊断年轻发病的成人型糖尿病（MODY）的难题及新型HNF1A变异DOI: 10.1186/s40348-026-00229-0
Current diabetes report IF: 06.400Volume 26, Issue 1No.119Correction: Glucagon-Like Peptide-1 and Dual Incretin Agonists in Type 2 Diabetes with Peripheral Artery Disease: A Systematic Review and Meta-Analysis of Vascular, Cardiovascular, Metabolic, and Mortality Outcomes修正：胰高血糖素样肽-1和双重肠促胰素激动剂在合并外周动脉疾病的2型糖尿病中的应用：血管、心血管、代谢和死亡率结局的系统综述与荟萃分析DOI: 10.1007/s11892-026-01622-9
Acta diabetologica IF: 02.900Ahead of Print.No.120Diabetes mellitus and risk of endometrial cancer: an updated systematic review and meta-analysis糖尿病与子宫内膜癌风险：更新的系统综述与荟萃分析DOI: 10.1007/s00592-026-02681-w
Osteoporosis international IF: 05.400Ahead of Print.No.121Romosozumab versus teriparatide and risk of all-cause mortality in patients with osteoporosis: a real-world propensity score-matched cohort study罗莫佐单抗与特立帕肽在骨质疏松症患者中的全因死亡率风险比较：一项真实世界倾向评分匹配队列研究DOI: 10.1007/s00198-026-07968-w
Osteoporosis international IF: 05.400Ahead of Print.No.122Adjusting fracture probability according to duration of diabetes: the Manitoba BMD Registry根据糖尿病病程调整骨折概率：曼尼托巴骨密度登记处DOI: 10.1007/s00198-026-08001-w
Endocrine connections IF: 02.800Ahead of Print.No.123Mapping Transition of Care for Rare Endocrine Conditions: Findings from a Cross-Sectional Survey by the Endo-ERN ToC Working Group罕见内分泌疾病的护理过渡映射：Endo-ERN护理过渡工作组横断面调查结果DOI: 10.1530/EC-25-0798
Invest Ophthalmol Vis Sci IF: 04.700Volume 67, Issue 4No.124Age-Specific Increases in the Prevalence and Treatment Burden of Neovascular Age-Related Macular Degeneration in a Super-Aged Society超老龄化社会中新生血管性年龄相关性黄斑变性的患病率和治疗负担的年龄特异性增加DOI: 10.1167/iovs.67.4.19
Int J Low Extrem Wounds IF: 01.500Ahead of Print.No.125Assessment of the Comprehensive Score for Financial Toxicity (COST) among People with Diabetic Foot Ulcers at a Tertiary Care Centre in South India南印度三级医疗中心糖尿病足溃疡患者财务毒性综合评分（COST）评估DOI: 10.1177/15347346261441107
J Am Coll Surg IF: 03.400Ahead of Print.No.126Increasing Use of Wearable Devices for Health or Activity Tracking Among Adults with Chronic Diseases in the US美国慢性病成年人群中用于健康或活动追踪的可穿戴设备使用量增加DOI: 10.1097/XCS.0000000000001746
Int J Gynaecol Obstet IF: 02.400Ahead of Print.No.127Polycystic ovarian syndrome and perinatal outcomes: A population-based pooled cross-sectional study多囊卵巢综合征与围产期结局：一项基于人群的汇总横断面研究DOI: 10.1002/ijgo.71006
Curr Opin Endocrinol Diabetes Obes IF: 02.700Ahead of Print.No.128Parathyroid hormone assays in 2026: second versus third generation, standardization, and clinical interpretation2026年甲状旁腺激素检测：第二代与第三代、标准化及临床解读DOI: 10.1097/MED.0000000000000960
Diabetes therapy IF: 02.600Ahead of Print.No.129Tirzepatide as an Add-on for Participants with Inadequate Glycemic Control Using Basal Insulin: Pooled Subgroup Analysis of SURPASS-5 and -6替尔泊肽作为基础胰岛素治疗血糖控制不佳参与者的附加治疗：SURPASS-5和-6研究的合并亚组分析DOI: 10.1007/s13300-026-01859-3
European journal of pain IF: 03.400Volume 30, Issue 4No.130Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta-Analyses and Trial Sequential Analyses腰椎间盘切除术后的术后疼痛管理：一项系统综述、荟萃分析及试验序贯分析DOI: 10.1002/ejp.70261
BioMed research international IF: 02.300Volume 2026, Issue 1No.131Bacteria Associated With Urinary Tract Infections, Antimicrobial Resistance Profiles, and Associated Factors Among Diabetes Mellitus Patients at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia埃塞俄比亚西北部德布雷塔布尔综合专科医院糖尿病患者尿路感染相关细菌、抗菌药物耐药谱及相关因素DOI: 10.1155/bmri/6664132
Eur J Ophthalmol IF: 01.400Ahead of Print.No.132The impact of polycystic ovarian syndrome on ocular health多囊卵巢综合征对眼部健康的影响DOI: 10.1177/11206721261436102
Nutrición hospitalaria IF: 01.100Ahead of Print.No.133Effects of betaine-containing nutrients on homocysteine levels and glucose-lipid metabolism in overweight and obese patients with hyperhomocysteinemia甜菜碱类营养物质对伴有高同型半胱氨酸血症的超重和肥胖患者的同型半胱氨酸水平及糖脂代谢的影响DOI: 10.20960/nh.05892
Nutrición hospitalaria IF: 01.100Ahead of Print.No.134[Triglycerides glucose index in Madrid university students]马德里大学生甘油三酯葡萄糖指数DOI: 10.20960/nh.06225
Med Lett Drugs Ther IF: 01.400Volume 68, Issue 1752No.135In brief: Rybelsus R2 rebranded as Ozempic简要介绍：Rybelsus R2重命名为OzempicDOI: 10.58347/tml.2026.1752f
Am J Phys Med Rehabil IF: 02.400Ahead of Print.No.136Semaglutide-Associated Sequential Unilateral Transient Osteoporosis of The Hip: A Case Report司美格鲁肽相关序贯单侧髋部暂时性骨质疏松症：一例报告DOI: 10.1097/PHM.0000000000003003
Diabetes therapy IF: 02.600Ahead of Print.No.137Fixed-Dose Combination Therapy as a Strategy to Improve Antidiabetic Medication Adherence in People with Type 2 Diabetes: A Narrative Review固定剂量联合疗法作为提高2型糖尿病患者抗糖尿病药物依从性的策略：一项叙述性综述DOI: 10.1007/s13300-026-01863-7
Infectious diseases and therapy IF: 05.300Ahead of Print.No.138Burden of Respiratory Syncytial Virus in Older ADults in Nagasaki, Japan (Nagasaki ROAD): Preliminary Results (April 2024-March 2025) of a Prospective, Multicenter, Epidemiological Study日本长崎地区老年人群呼吸道合胞病毒（RSV）负担（Nagasaki ROAD研究）：2024年4月-2025年3月前瞻性多中心流行病学研究初步结果DOI: 10.1007/s40121-026-01312-9
Journal of obesity IF: 03.900Volume 2026, Issue 1No.139Expression Analysis of Selected microRNAs in Diabetes Mellitus Visceral Fat Tissues糖尿病内脏脂肪组织中选定微小RNA的表达分析DOI: 10.1155/jobe/3230015
Clin J Am Soc Nephrol IF: 07.100Ahead of Print.No.140Expanding Evidence for Glucagon-Like Peptide-1 Receptor Agonists in Those with Diabetes and Kidney Disease胰高血糖素样肽-1受体激动剂在糖尿病和肾病患者中的证据扩展DOI: 10.2215/CJN.0000001072
JAMA Network Open IF: 09.700Volume 9, Issue 4No.141Risk Prediction Model for Taxane-Induced Peripheral Neuropathy in Early-Stage Cancer早期癌症中紫杉醇诱导的周围神经病变风险预测模型DOI: 10.1001/jamanetworkopen.2026.4901
Eur J Appl Physiol IF: 02.700Ahead of Print.No.142Hyperlactatemia and pulmonary gas exchange at rest and during exercise: lessons from patients on metformin高乳酸血症与静息及运动时的肺气体交换：二甲双胍治疗患者的启示DOI: 10.1007/s00421-026-06213-w
JAMA IF: 55.000Ahead of Print.No.143PCSK9 Inhibitors in Diabetes, Tirzepatide's Cardiorenal Effects, Shingles Vaccine, and More From ACC糖尿病中的PCSK9抑制剂、替尔泊肽的心脏肾脏影响、带状疱疹疫苗及ACC其他相关内容DOI: 10.1001/jama.2026.2399
Acta diabetologica IF: 02.900Ahead of Print.No.144The silent side effect of metformin: understanding Vitamin B12 deficiency in Type 2 Diabetes二甲双胍的隐性副作用：认识2型糖尿病中的维生素B12缺乏症DOI: 10.1007/s00592-026-02684-7
J Interv Cardiol IF: 01.700Volume 2026, Issue 1, Page 5898802-5898802No.145Gentamicin–Collagen Sponge Use in the Implant Pocket for the Prevention of Cardiac Implantable Electronic Device Infections庆大霉素-胶原海绵用于植入袋预防心脏植入式电子设备感染DOI: 10.1155/joic/9922994
Int J Hepatol IF: 01.400Volume 2026, Issue No.146Natriuretic Effect of Dapagliflozin in Cirrhosis With Ascites: A Randomized, Placebo-Controlled Crossover Trial达格列净对肝硬化腹水患者尿钠排泄及临床结局的影响：一项随机、双盲、安慰剂对照交叉试验DOI: 10.1155/ijh/9503323
Public health nursing IF: 01.300Ahead of Print.No.147Enhancing Community-Based Nursing Decision Support: Machine Learning Models for Diabetes Risk Prediction Using Home Health Nursing Notes增强基于社区的护理决策支持：利用家庭健康护理记录进行糖尿病风险预测的机器学习模型DOI: 10.1111/phn.70122
Bioinformation IF: 01.900Volume 22, Issue 1No.148Obesity and periodontal diseases: A review肥胖与牙周疾病：综述DOI: 10.6026/973206300220392
Bioinformation IF: 01.900Volume 22, Issue 1No.149Smoking and its impact on eating behavior: A review吸烟及其对进食行为的影响：综述DOI: 10.6026/973206300220132
J Health Dispar Res PractVolume 10, Issue 2No.150Investigation of the Cultural Context of Sugars Consumption Behavior in Low-Income Mexican-American Women美国墨西哥裔美国母亲的食品采购、制备及呈现行为与糖消费研究：焦点小组研究https://pubmed.ncbi.nlm.nih.gov/41960351
Research squareVolume 2026, Issue No.151Metabolic Adaptations to Caloric Restriction: Time- and Group-Dependent Metabolomic Signatures from the CALERIE™ Trial热量限制调节健康成年人的血浆代谢组：来自CALERIE试验的纵向代谢组学分析DOI: 10.21203/rs.3.rs-9237764/v1
J Coll Med S AfrVolume 4, Issue 1No.152A unique case report of bilateral spontaneous cerebrospinal fluid leak from bilateral sphenoid sinus skull base defects双侧蝶窦颅底缺损致双侧自发性脑脊液漏的独特病例报告DOI: 10.4102/jcmsa.v4i1.271
Frontiers in pediatrics IF: 02.000Volume 14, Issue No.153Impact of pediatric obesity on abdominal surgery outcome: a narrative review儿童肥胖与腹部手术：围手术期并发症及管理策略的叙事性综述DOI: 10.3389/fped.2026.1780811
Curēus IF: 01.300Volume 18, Issue 3No.154Impact of Pre-pregnancy BMI and Gestational Weight Gain on Fetomaternal Outcomes: A Cross-Sectional Analytical Study孕前体重指数和孕期增重对母婴结局的影响DOI: 10.7759/cureus.104941
Osteoarthr Cartil Open IF: 02.800Volume 8, Issue 2No.155Implementing a guideline-based model of care for hip and knee osteoarthritis in Finland (FIN-OA): Protocol for a benchmarking-controlled trial芬兰国家骨关节炎实施（FIN-OA）试验：基层医疗中基于指南的髋膝关节骨关节炎护理模式的混合3型基准对照试验方案DOI: 10.1016/j.ocarto.2026.100782
Surgery in practice and science IF: 00.600Volume 25, Issue No.156Comment on "Associations between obesity and lymph node metastasis and early recurrence in pancreatic head cancer: A single-center retrospective cohort study"对“胰头癌中肥胖与淋巴结转移及早期复发的关联：单中心回顾性队列研究”的评论DOI: 10.1016/j.sipas.2026.100342
bioRxivVolume 2026, Issue No.157Cognitive reappraisal of food and emotion cues involves common and unique neural contributions参考文献列表DOI: 10.64898/2026.03.09.710570
bioRxivVolume 2026, Issue No.158Adrβ2 in skeletal muscle cells is required for exercise-induced Pgc1α but not for metabolic benefits of exercise on diet-induced obesity骨骼肌中的Adrβ2对于运动在饮食诱导肥胖中的代谢益处并非必需DOI: 10.64898/2026.03.27.714812
bioRxivVolume 2026, Issue No.159Hypothalamus amyloid levels are associated with early sex-dependent alterations in energy homeostasis in TgF344-AD rats下丘脑淀粉样蛋白水平与TgF344-AD大鼠早期能量稳态的性别依赖性改变相关DOI: 10.64898/2026.03.08.710398
bioRxivVolume 2026, Issue No.160Diet quality shapes development and feeding circuits in poison frog tadpoles饮食质量影响箭毒蛙蝌蚪的发育与摄食回路DOI: 10.64898/2026.03.28.714959
bioRxivVolume 2026, Issue No.161Spontaneous Pregravid Obesity Reshapes Fetal Immune Ontogeny in a Nonhuman Primate Model自发性孕前肥胖在非人灵长类模型中重塑胎儿免疫发育DOI: 10.64898/2026.03.27.714880
J Indian Assoc Pediatr SurgVolume 31, Issue 2No.162Chemoport Placement in Children Who are Overweight or Obese: A Practical Approach儿童超重或肥胖时的Chemoport放置：一种实用方法DOI: 10.4103/jiaps.jiaps_379_25
J Hum Reprod Sci IF: 01.100Volume 19, Issue 1No.163Psychological Morbidity (Stress, Anxiety and Depression) and Fertility Quality of Life amongst Infertile Women with and without Polycystic Ovary Syndrome (PCOS): A Cross-sectional Study多囊卵巢综合征（PCOS）有无的不孕女性心理疾病（压力、焦虑和抑郁）与生育生活质量：一项横断面研究DOI: 10.4103/jhrs.jhrs_241_25
Frontiers in medicine IF: 03.000Volume 13, Issue No.164The effect of iron treatment on fetal fraction according to gestational weeks in maternal anemia非侵入性产前检测中母体血液学参数和铁补充对胎儿分数的影响：一项队列研究DOI: 10.3389/fmed.2026.1772334
HSS journal : IF: 01.300Ahead of Print.No.165Preoperative GLP-1 Receptor Agonist Use Is Not Associated With Complications in Non-Obese Patients Undergoing Total Shoulder Arthroplasty: A Propensity Score Matched Large Database Analysis围手术期使用胰高血糖素样肽-1受体激动剂与非肥胖患者全肩关节置换术后并发症增加无关DOI: 10.1177/15563316261439127
Addiction IF: 05.300Ahead of Print.No.166A genetically informed cross-lagged twin study of the longitudinal association between addiction-related behaviors and obesity基于遗传学的交叉滞后双胞胎研究：成瘾相关行为与肥胖的纵向关联DOI: 10.1111/add.70407
Obesity reviews IF: 07.400Ahead of Print.No.167How Does the Ultra-Processed Food Industry Drive Consumption Through Product Design and Marketing? Mapping a Complex Commercial System According to Expert Mental Models and Evidence Review超加工食品行业如何通过产品设计和营销推动消费？基于专家心智模型与证据综述的复杂商业系统解析DOI: 10.1111/obr.70135
Diabetes & metabolism journal IF: 08.500Ahead of Print.No.168Obesity Transitions by Age, Period, and Cohort: A Population-Based Application of the Lancet Commission Framework in the United States and Korea不同年龄、时期和队列的肥胖转变：美国和韩国基于人群的《柳叶刀》委员会框架应用DOI: 10.4093/dmj.2025.0918
International journal of cancer IF: 04.700Ahead of Print.No.169At what age should people with obesity start colorectal cancer screening?肥胖人群应从什么年龄开始结直肠癌筛查？DOI: 10.1002/ijc.70448
Annals of African medicine IF: 00.600Ahead of Print.No.170The Impact of Competency-based Medical Education-mandated Yoga Training on First-Year Medical Students: A Quasi-experimental Study基于能力的医学教育要求的瑜伽训练对一年级医学生的影响：一项类实验研究DOI: 10.4103/aam.aam_869_25
J Integr Complement Med IF: 01.700Ahead of Print.No.171Osteopathic Visceral Manipulation on Functional Constipation in Obese Adults: A Randomized Controlled Clinical Trial整骨内脏手法对肥胖成人功能性便秘的随机对照临床试验DOI: 10.1177/27683605261427696
Lipids in health and disease IF: 04.200Ahead of Print.No.172Serum metabolite patterns of adipose tissue distribution and body composition subphenotypes血清代谢物模式与脂肪组织分布及身体成分亚型DOI: 10.1186/s12944-026-02944-z
Int J Behav Nutr Phys Act IF: 05.500Ahead of Print.No.173Socioeconomic inequalities in exposure to neighbourhood environments for physical activity: a systematic review体力活动相关社区环境暴露的社会经济不平等：一项系统综述DOI: 10.1186/s12966-026-01912-1
bioRxivVolume 2026, Issue No.174Empagliflozin preserves cardiac function and modulates metabolism in a mouse model of Duchenne muscular dystrophy恩格列净在杜氏肌营养不良症小鼠模型中维持心脏功能并调节代谢DOI: 10.64898/2026.03.11.710889
Curēus IF: 01.300Volume 18, Issue 3No.175Lacunar Pontine Infarct Presenting as Ipsilateral Lower Motor Neuron Facial Palsy: A Case Report腔隙性脑桥梗死表现为同侧下运动神经元面瘫：一例报告DOI: 10.7759/cureus.104930
Shoulder & elbow IF: 01.100Ahead of Print.No.176Perioperative testosterone therapy linked to higher 5-year risk of periprosthetic joint infection without increased 90-day major complications or revision rates in total shoulder arthroplasty围手术期睾酮治疗与初次肩关节置换术后5年假体周围关节感染风险增加相关但90天并发症无增加DOI: 10.1177/17585732261437972
Mol Nutr Food Res IF: 04.200Volume 70, Issue 7No.177Ellagic Acid Reduces Inulin's Adverse Effects: A Combined Approach to Enhance Therapeutic Potential in Nonalcoholic Steatohepatitis鞣花酸减轻菊粉的不良反应：联合方法增强非酒精性脂肪性肝炎的治疗潜力DOI: 10.1002/mnfr.70456
Journal of medicine and lifeVolume 19, Issue 2No.178Epigenetic alterations in preeclampsia: a systematic review of current mechanisms and biomarker potential子痫前期中的表观遗传失调：2022-2025年分子与临床特征的系统综述与荟萃分析DOI: 10.25122/jml-2026-0009
Acta Obstet Gynecol Scand IF: 03.100Ahead of Print.No.179Perinatal and long-term implications of diagnosing gestational diabetes mellitus using only fasting and one-hour post-load glucose concentrations: Secondary analysis of the GEMS trial and its five-year follow-up仅用空腹和1小时负荷后血糖诊断妊娠糖尿病的围产期及长期影响：GEMS试验及其五年随访的二次分析DOI: 10.1111/aogs.70191
Bioinformation IF: 01.900Volume 22, Issue 1No.180A case of takayasu arteritis presenting with multiple cerebral infarcts: Diagnostic and therapeutic challenges一例以多发脑梗死为表现的Takayasu动脉炎：诊断与治疗挑战DOI: 10.6026/973206300220071
Bioinformation IF: 01.900Volume 22, Issue 1No.181The impact of obesity, smoking and diabetes on the susceptibility to postoperative spinal infections: A risk-based approach肥胖、吸烟和糖尿病对术后脊柱感染风险的影响DOI: 10.6026/973206300220409
Bioinformation IF: 01.900Volume 22, Issue 1No.182Clinicopathological and microbiological profile of osteomyelitis at a teaching hospital in India: A retrospective study印度某教学医院骨髓炎的临床病理和微生物学特征回顾性研究DOI: 10.6026/973206300220443
Bioinformation IF: 01.900Volume 22, Issue 1No.183Fitness assessment to promote exercise for diabetes and hypertension用于促进糖尿病和高血压患者运动的体质评估DOI: 10.6026/973206300220142
Bioinformation IF: 01.900Volume 22, Issue 1No.184Sarcopenia with postoperative outcomes in patients undergoing pancreaticoduodenectomy胰十二指肠切除术后患者的肌少症及其术后结局DOI: 10.6026/973206300220066
Bioinformation IF: 01.900Volume 22, Issue 1No.185Early thiamine therapy in Rogers syndrome: Systematic review of hematologic, auditory and glycemic outcomes罗杰斯综合征早期硫胺素治疗：血液学、听觉和血糖结局的系统综述DOI: 10.6026/973206300220026
Bioinformation IF: 01.900Volume 22, Issue 1No.186Periodontal severity and metabolic syndrome: A cross-sectional study from a tertiary care hospital in India印度一家三级医疗机构牙周炎严重程度与代谢综合征的横断面研究DOI: 10.6026/973206300220477
Bioinformation IF: 01.900Volume 22, Issue 1No.187Treatment outcomes and clinical characteristics in diabetic versus non-diabetic sinonasal tuberculosis糖尿病与非糖尿病患者鼻窦结核的治疗结局及临床特征对比DOI: 10.6026/973206300220206
Frontiers in public health IF: 03.400Volume 14, Issue No.188Impact of a brief diabetes education on teachers' diabetes-related knowledge, attitude, and confidence: a nonrandomized school-based intervention study标准化糖尿病教育课程对教师1型糖尿病管理知识态度和信心的短期影响DOI: 10.3389/fpubh.2026.1747185
Research squareVolume 2026, Issue No.189Abdominal Waist Circumference and Subcutaneous Adipose Tissue Thickness Predicts Development of Post-Transplant Diabetes Mellitus肾移植后糖尿病风险预测中腹部皮下脂肪厚度和腰围的应用：一项回顾性队列研究DOI: 10.21203/rs.3.rs-8543193/v1
Research squareVolume 2026, Issue No.190Risk Factors for Hepatocellular Carcinoma: Findings from a Case-Control Study in Vietnam越南人群肝细胞癌的风险因素DOI: 10.21203/rs.3.rs-8383243/v1
Research squareVolume 2026, Issue No.191Epidemiological and Multi-Omics Investigation of Phytosterol Intake and Type 2 Diabetes Risk植物甾醇摄入与2型糖尿病风险的流行病学及多组学研究DOI: 10.21203/rs.3.rs-9222420/v1
South Afr J HIV Med IF: 02.300Volume 27, Issue 1No.192Cardiovascular risk profiles in people living with HIV taking antiretroviral therapy in rural Lesotho: Findings from the PRECARIF study莱索托农村地区接受抗逆转录病毒治疗的HIV感染者心血管疾病风险特征：PRECARIF研究结果DOI: 10.4102/sajhivmed.v27i1.1779
Case Rep Obstet Gynecol IF: 00.600Volume 2026, Issue No.193Intrauterine Tampon Identified on CT as an Intrauterine Foreign Body Associated With Bilateral Leg Edema: A Case ReportCT显示宫内棉条为宫内异物并伴双侧腿部水肿：一例报告DOI: 10.1155/crog/1505612
Bioimpacts IF: 02.200Volume 16, Issue No.194Three-dimensional bioprinted hydrogels for the management of diabetic wounds: A review3D打印技术在糖尿病伤口愈合中的应用进展：综合综述DOI: 10.34172/bi.32751
Curēus IF: 01.300Volume 18, Issue 3No.195Incidence of Sepsis After Transrectal Ultrasound-Guided Prostate Biopsy in Dubai Tertiary Care Hospitals: A Multicenter Cohort Study迪拜三家三级医院经直肠超声引导前列腺穿刺活检术后脓毒症发生率：一项多中心队列研究DOI: 10.7759/cureus.104933
Curēus IF: 01.300Volume 18, Issue 3No.196Health-Seeking Behavior for Noncommunicable Diseases in Rural and Urban Areas of Ernakulam District, Kerala: A Cross-Sectional Study喀拉拉邦厄纳库拉姆地区城乡居民非传染性疾病就医行为比较研究DOI: 10.7759/cureus.104899
Int J Breast Cancer IF: 03.000Volume 2026, Issue No.197Modifiable and Nonmodifiable Risk Factors for Breast Cancer: A Comprehensive Scoping Review乳腺癌风险因素：综合综述DOI: 10.1155/ijbc/8689986
Case reports in endocrinology IF: 00.900Volume 2026, Issue No.198A Rare Primary Adrenal Malignancy Manifesting as a Hemorrhagic Mass: Case Report and Literature Review罕见原发性肾上腺恶性肿瘤表现为出血性肿块：病例报告及文献综述DOI: 10.1155/crie/1260707
Curēus IF: 01.300Volume 18, Issue 4No.199Assessing Functional Outcomes and Complications After Turndown Flap With Flexor Hallucis Longus Augmentation in Chronic Achilles Tendon Ruptures腓肠肌下翻瓣联合拇长屈肌增强治疗慢性跟腱断裂的回顾性病例系列研究DOI: 10.7759/cureus.106610
ACG case reports journal IF: 00.500Volume 13, Issue 4No.200Semaglutide-Induced Symptomatic Remission in Ulcerative Colitis司美格鲁肽诱导溃疡性结肠炎的症状缓解DOI: 10.14309/crj.0000000000002070
bioRxivVolume 2026, Issue No.201Deletion of endothelial KLF4 as a model for preeclampsia内皮KLF4缺失诱导小鼠子痫前期DOI: 10.64898/2026.03.30.715448
bioRxivVolume 2026, Issue No.202Synthetic Immunological Niche Reveals Early Immune Dysregulation and Stratifies Therapeutic Response in Type 1 Diabetes工程化免疫微环境揭示1型糖尿病中阶段特异性免疫失调及预测治疗效果DOI: 10.64898/2026.03.06.710219
bioRxivVolume 2026, Issue No.203Exploring Links between Brain Image-Derived Phenotypes and Accelerometer-Measured Physical Activity in the UK Biobank体力活动与脑成像：英国生物样本库中功能连接性和灰质体积的综合分析DOI: 10.64898/2026.03.10.710798
bioRxivVolume 2026, Issue No.204Serum proteomics reveals distinct phenotypic signatures to IL-6 blockade between two immunotherapies血清蛋白质组学揭示两种免疫疗法在IL-6阻断时的不同表型特征DOI: 10.64898/2026.03.27.712461
bioRxivVolume 2026, Issue No.205Aberrant immune regulation and enrichment of stem-like CD8 (+) T cells in the pancreatic lymph node during type 1 diabetes development1型糖尿病发展过程中胰腺淋巴结中异常免疫调节及类干细胞样CD8(+)T细胞的富集DOI: 10.1101/2025.05.23.655848
Kidney international reports IF: 05.700Volume 11, Issue 5No.206Response to the Letter to the Editor Entitled "Beyond Access: How Homelessness Shapes Kidney Trajectories in Diabetes"对题为‘超越获取：无家可归如何影响糖尿病患者肾脏轨迹’的信件的回应DOI: 10.1016/j.ekir.2026.106381
Imaging Neurosci (Camb)Volume 4, Issue No.207Retinal nerve fibre layer thickness reflects characteristics of brain grey and white matter视网膜神经纤维层厚度反映大脑灰白质特征DOI: 10.1162/IMAG.a.1174
JMA journal IF: 01.800Volume 9, Issue 2No.208Melioidosis Presenting as Parapharyngeal Abscess类鼻疽表现为咽旁脓肿DOI: 10.31662/jmaj.2025-0546
Frontiers in medicine IF: 03.000Volume 13, Issue No.209Acupuncture in the treatment of inflammation-related ocular degenerations: a systematic review针灸治疗炎症相关眼部退行性病变：一项系统综述DOI: 10.3389/fmed.2026.1749297
HSS journal : IF: 01.300Ahead of Print.No.210The Outpatient Surge in Total Hip Arthroplasty: National Trends in Volume Migration, Demographic Disparities, and Comorbidity Profiles (2019-2022)全髋关节置换术在住院与门诊环境中的比例：全国趋势、人口统计学和合并症（2019-2022）DOI: 10.1177/15563316261431234
Journal of medicine and lifeVolume 19, Issue 2No.211Correlations between Psoriasis Area and Severity Index (PASI), body mass index (BMI), smoking, and alcohol consumption in patients with psoriasis - a Romanian study银屑病患者中银屑病面积和严重程度指数（PASI）、体重指数（BMI）、吸烟和饮酒之间的相关性——一项罗马尼亚研究DOI: 10.25122/jml-2026-0013
Journal of materials chemistry IF: 05.700Ahead of Print.No.212H(2)O(2) responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis对H₂O₂响应的若丹明基探针用于早期糖尿病诊断监测DOI: 10.1039/d5tb02687c
Nuclear medicine communications IF: 01.300Ahead of Print.No.213Pilot feasibility study investigating 68Ga-NODAGA-RGD PET-computed tomography molecular angiogenesis imaging in patients with peripheral arterial diseases: can it be of potential clinical value?初步可行性研究：68Ga-NODAGA-RGD PET-CT分子血管生成成像在外周动脉疾病患者中的潜在临床价值探讨DOI: 10.1097/MNM.0000000000002160
British journal of nutrition IF: 03.000Ahead of Print.No.214Cardiometabolic health effects of dietary counselling on a high-quality, fibre-rich diet in adults with type 2 diabetes: A randomised controlled trial饮食咨询对成年2型糖尿病患者高质量高纤维饮食的心脏代谢健康影响：一项随机对照试验DOI: 10.1017/S0007114526107041
Stroke IF: 08.900Ahead of Print.No.215Cost-Effectiveness of Prehospital Delay Reduction Versus Primary Stroke Prevention in US Adults With Type 2 Diabetes美国2型糖尿病成年人减少院前延误与一级卒中预防的成本效益比较DOI: 10.1161/STROKEAHA.126.055187
Prim Health Care Res Dev IF: 01.700Volume 27, Issue No.216From silos to synergy: assessing tuberculosis basic management units readiness for integrated diabetes mellitus care across different districts of Pakistan从孤立到协同：评估巴基斯坦不同地区结核病基层管理单位开展糖尿病综合管理的准备情况DOI: 10.1017/S146342362610111X
Public health nutrition IF: 03.000Ahead of Print.No.217Dietary Knowledge and Perceptions in UK Pakistani/Bangladeshi Communities: A Survey on Low-Carbohydrate and Intermittent Fasting diets for Diabetes Prevention and Management英国巴基斯坦/孟加拉裔社区的饮食知识与认知：关于低碳水化合物和间歇性禁食饮食对糖尿病预防和管理的调查DOI: 10.1017/S136898002610250X
Chemistry & biodiversity IF: 02.500Volume 23, Issue 4No.218Capparis Spinosa and Glutamine Reduce Oxidative Stress via Nrf2/Ho-1 Pathway in Diabetic Wound Healing刺山柑与谷氨酰胺通过Nrf2/HO-1通路减轻糖尿病创面愈合中的氧化应激DOI: 10.1002/cbdv.71196
Sci Diabetes Self Manag Care IF: 02.200Ahead of Print.No.219Transition to Virtual Diabetes Self-Management Education Delivery in the Setting of Health Care Disruption for Adults With Diabetes and Their Support Persons医疗保健中断背景下，成年糖尿病患者及其支持者向虚拟糖尿病自我管理教育交付的转变DOI: 10.1177/26350106261432172
Annals of African medicine IF: 00.600Ahead of Print.No.220Role of Renal Doppler and Shearwave Elastography in Diabetic Nephropathy肾多普勒超声和剪切波弹性成像在糖尿病肾病中的作用DOI: 10.4103/aam.aam_877_25
Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.221Biological Context and Endpoint Alignment Are Critical for Interpreting Population-Based Validation of Cluster-Based MASLD Subtypes生物学背景和终点对齐对解释基于人群的聚类代谢相关脂肪性肝病（MASLD）亚型验证至关重要DOI: 10.1111/dom.70627
Ethnicity & health IF: 02.000Ahead of Print.No.222Overcoming barriers to blood glucose monitoring: the mediating role of social cognitive theory components in black/African American men with type 2 diabetes克服血糖监测障碍：社会认知理论组成部分在黑人/非裔美国2型糖尿病男性中的中介作用DOI: 10.1080/13557858.2026.2655624
Am J Surg Pathol IF: 04.200Ahead of Print.No.223Segmental Atrophy of the Liver: An Increasingly Recognized Pseudotumor With Distinct Clinicopathologic and Imaging Features肝脏节段性萎缩：一种日益被认识的具有独特临床病理和影像学特征的假瘤DOI: 10.1097/PAS.0000000000002543
Curēus IF: 01.300Volume 18, Issue 3No.224Human Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) and p16 Expression in Squamous Cell Carcinoma of the Head and Neck人乳头瘤病毒(HPV)状态及p16INK4a、IMP3在头颈部鳞状细胞癌(HNSCC)中的表达DOI: 10.7759/cureus.104895
Genes & diseases IF: 09.400Volume 13, Issue 4No.225FOXA2 in islet biology: Orchestrating pancreatic development and glucose homeostasisFOXA2在胰腺胰岛生物学中的作用：调控发育、功能与疾病DOI: 10.1016/j.gendis.2025.101972
Pediatric diabetes IF: 05.600Volume 2026, Issue No.226Achieving Glycemic Targets in and out-of-School: Real-World Data From 1341 Italian Children Using the MiniMed 780G System During Auto Mode意大利1341名儿童使用MiniMed 780G自动模式系统在学校内外实现血糖目标的真实世界数据DOI: 10.1155/pedi/1653728
bioRxivVolume 2026, Issue No.227Desynchrony between events triggers a compensatory delay during C. elegans development秀丽隐杆线虫发育过程中事件不同步触发补偿性延迟DOI: 10.1101/2024.03.31.587169
bioRxivVolume 2026, Issue No.228Profiling Peripheral Blood with an Optimized, Multiplexed, Single-cell Multiome Approach Supports an Insulin-driven Asthma Subtype采用优化的多重单细胞多组学方法分析外周血支持胰岛素驱动的哮喘亚型DOI: 10.64898/2026.03.27.714744
bioRxivVolume 2026, Issue No.229Sex and breeding stage differences in neurogenomic profiles reflect hormone signaling in a socially polyandrous shorebird社会性一妻多夫制滨鸟中神经基因组谱的性别和繁殖阶段差异反映激素信号DOI: 10.64898/2026.03.10.710941
bioRxivVolume 2026, Issue No.230A high-resolution mass spectrometry-based method for quantifying insulin-stimulated glucose uptake in mice following an intraperitoneal injection of tracer腹腔注射示踪剂后基于高分辨率质谱的小鼠胰岛素刺激葡萄糖摄取定量方法DOI: 10.64898/2026.03.31.714892
bioRxivVolume 2026, Issue No.231Biosensor Cell Array Reveals Temporal GABA Secretion Dynamics from Pancreatic Islets生物传感器细胞阵列揭示胰岛GABA分泌的时间动态DOI: 10.64898/2026.03.31.715660
bioRxivVolume 2026, Issue No.232Functional genomics reveals mediators of beta cell survival in ER stress and type 2 diabetes risk胰腺β细胞应激反应的单细胞多组学分析鉴定2型糖尿病风险机制DOI: 10.64898/2026.03.30.715154
bioRxivVolume 2026, Issue No.233Sleeve gastrectomy protects lean mice from future obesity减重手术减轻高脂饮食诱导小鼠的代谢恶化DOI: 10.64898/2026.03.09.710623
Frontiers in endocrinology IF: 04.600Volume 17, Issue No.234Correction: Intrinsic, pro-apoptotic effects of IGFBP-3 on breast cancer cells are reversible: involvement of PKA, Rho, and ceramide更正：IGFBP-3对乳腺癌细胞的内在促凋亡作用具有可逆性：涉及PKA、Rho和神经酰胺DOI: 10.3389/fendo.2026.1810747
Annals of African medicine IF: 00.600Ahead of Print.No.235Association of Serum Leptin with Insulin Resistance in Obese and Nonobese Patients with Type 2 Diabetes Mellitus: A Case-control Study from Eastern India血清瘦素与肥胖和非肥胖2型糖尿病患者胰岛素抵抗的关联：来自印度东部的病例-对照研究DOI: 10.4103/aam.aam_65_26
Bioinformation IF: 01.900Volume 22, Issue 1No.236Linking diabetic retinopathy with lipid abnormalities糖尿病视网膜病变与脂质异常的关联DOI: 10.6026/973206300220128
Bioinformation IF: 01.900Volume 22, Issue 1No.237The prevalence of anemia among type 2 diabetes mellitus with respect to renal function at a tertiary care hospital: A case-control study三级护理医院中2型糖尿病患者贫血患病率与肾功能的关系：一项病例对照研究DOI: 10.6026/973206300220353
Mayo Clinic proceedings. Digital healthVolume 4, Issue 2No.238Patients' Perspectives on Telemedicine for Type 2 Diabetes in Primary Care: Systematic Review and Thematic Synthesis2型糖尿病患者在基层医疗中使用远程医疗的观点：系统综述与主题综合分析DOI: 10.1016/j.mcpdig.2025.100333
bioRxivVolume 2026, Issue No.239Pharmacologic DPP-4 inhibition promotes CD8⁺ T cell metabolic fitness to enhance anti-tumor activity药理DPP-4抑制促进CD8⁺ T细胞代谢适应性以增强抗肿瘤活性DOI: 10.64898/2026.03.31.715681
BMC public health IF: 03.600Ahead of Print.No.240Incidence and predictors of diabetic ketoacidosis among adults with type 1 diabetes in Northwest, Ethiopia, 2023: a retrospective cohort study2023年埃塞俄比亚西北部1型糖尿病成人患者糖尿病酮症酸中毒的发病率及预测因素：一项回顾性队列研究DOI: 10.1186/s12889-026-27281-9
Bioimpacts IF: 02.200Volume 16, Issue No.241Moroccan virgin olive oil triterpenes: HPLC-DAD-ELSD profiling and computational investigation of anti-diabetic potential摩洛哥初榨橄榄油三萜类化合物：HPLC-DAD-ELSD分析及抗糖尿病潜力的计算研究DOI: 10.34172/bi.31007
Curēus IF: 01.300Volume 18, Issue 3No.242Successful Pregnancy Post-Kidney Transplant: A Case Report肾移植术后成功妊娠病例报告DOI: 10.7759/cureus.104884
J Chin Med Assoc IF: 02.400Ahead of Print.No.243Beyond disease treatment and prevention: From geroscience and molecular hallmarks to gerotherapeutics and precision geromedicine超越疾病治疗与预防：从衰老科学与分子特征到衰老治疗与精准衰老医学DOI: 10.1097/JCMA.0000000000001374
Trials IF: 02.000Ahead of Print.No.244Applying a hypothetical strategy to the intercurrent event of non-adherence with the parametric g-formula: a post hoc secondary analysis of the MET-PREVENT randomised controlled trial应用参数化g公式处理不依从偶发事件的假设性策略：对MET-PREVENT随机对照试验的事后二次分析DOI: 10.1186/s13063-026-09708-1
Cardiology in the Young IF: 00.900Ahead of Print.No.245Obesity prevalence and risk factors in surgically repaired CHD手术修复的先天性心脏病患儿肥胖患病率及危险因素DOI: 10.1017/S1047951126111718
213
Diabetes Mellitus(DM)
糖尿病
118
Obesity
肥胖症
49
Insulin
胰岛素
20
Type 2 diabetes mellitus(T2DM)
2型糖尿病
15
Metabolic Syndrome
代谢综合征
14
Diabetic Retinopathy
糖尿病视网膜病
13
Gestational Diabetes Mellitus(GDM)
妊娠糖尿病
9
Metformin
二甲双胍
6
Glucagon-Like Peptide-1 Receptor Agonists(GLP-1RA)
胰高血糖素样肽-1受体激动剂
6
Diabetic Kidney Disease(DKD)
糖尿病肾脏病
5
Diabetic Foot
糖尿病足
3
Hypoglycemic Agents
降糖药
3
Semaglutide
司美格鲁肽
3
Tirzepatide
替尔泊肽
2
Dipeptidyl-Peptidase IV Inhibitors(DPP-4i)
二肽基肽酶-4抑制剂
2
Sitagliptin
西他列汀
2
Type 1 diabetes mellitus(T1DM)
1型糖尿病
2
Diabetic acidosis
糖尿病性酸中毒
2
Diabetic Cardiomyopathies
糖尿病心肌病
2
Dapagliflozin
达格列净
2
Empagliflozin
恩格列净
2
Gabapentin
加巴喷丁
1
Pregabalin
普瑞巴林
1
Diabetic Peripheral Neuropathy(PDN)
糖尿病周围神经病变
1
gamma-Aminobutyric Acid(GABA)
γ-氨基丁酸
1
Ipragliflozin
依格列净
1
Luseogliflozin
鲁格列净
1
Tofogliflozin
托格列净
1
Diabetes Complications
糖尿病并发症
1
Saxagliptin
沙格列汀
1
Linagliptin
利格列汀
1
Alogliptin
阿格列汀
1
Sodium-Glucose Transporter 2 Inhibitors(SGLT-2i)
钠-葡萄糖协同转运蛋白2抑制剂
1
Canagliflozin
卡格列净
1
Exenatide
艾塞那肽
1
Liraglutide
利拉鲁肽
编辑：韩玉莲
审校：韩玉莲
2026-04-10
根据《国家药监局关于发布药品说明书适老化及无障碍改革试点工作方案的公告》（2023年第142号），省级药品监管部门和国家药监局药品审评中心报送了参与试点的药品上市许可持有人和药品名单（第六批），现予公布。序号药品名称上市许可持有人1奥美沙坦酯片北京福元医药股份有限公司2复方α-酮酸片北京福元医药股份有限公司3替米沙坦片北京福元医药股份有限公司4艾司奥美拉唑镁肠溶干混悬剂北京福元医药股份有限公司5盐酸帕罗西汀片北京福元医药股份有限公司6盐酸文拉法辛缓释胶囊北京福元医药股份有限公司7依折麦布片北京福元医药股份有限公司8格列齐特缓释片北京福元医药股份有限公司9瑞格列奈片北京福元医药股份有限公司10米诺地尔搽剂北京诺博特生物科技有限公司11氟伐他汀钠缓释片北京诺华制药有限公司12卡马西平片北京诺华制药有限公司13利奈唑胺片华润赛科药业有限责任公司14氨氯地平阿托伐他汀钙片华润赛科药业有限责任公司15比索洛尔氨氯地平片华润赛科药业有限责任公司16苯磺酸氨氯地平片华润双鹤药业股份有限公司17阿普米司特片华润双鹤药业股份有限公司18别嘌醇片华润双鹤药业股份有限公司19联磺甲氧苄啶片华润双鹤药业股份有限公司20二甲双胍格列吡嗪胶囊华润双鹤药业股份有限公司21非诺贝特酸胆碱缓释胶囊华润双鹤药业股份有限公司22阿托伐他汀钙片北京伟林恒昌医药科技有限公司23盐酸奥洛他定片北京伟林恒昌医药科技有限公司24达格列净片北京伟林恒昌医药科技有限公司25达格列净二甲双胍缓释片（Ⅰ）北京伟林恒昌医药科技有限公司26强骨胶囊北京岐黄制药有限公司27双丹明目胶囊北京岐黄制药有限公司28氯沙坦钾氢氯噻嗪片津药达仁堂集团股份有限公司新新制药厂29盐酸地尔硫䓬片远大医药（天津）有限公司30盐酸地尔硫䓬缓释胶囊（II）远大医药（天津）有限公司31盐酸咪达普利片远大医药（天津）有限公司32盐酸沙格雷酯片远大医药（天津）有限公司33二甲双胍格列本脲片（II）津药达仁堂集团股份有限公司新新制药厂34托拉塞米分散片津药达仁堂集团股份有限公司新新制药厂35盐酸维拉帕米片天津市中央药业有限公司36阿替洛尔片天津市中央药业有限公司37冠心苏合软胶囊天津市中央药业有限公司38猴头菌提取物颗粒山西康欣药业有限公司39黄连上清丸好大夫制药有限公司40克林霉素磷酸酯片山西好医生药业有限公司41青霉素V钾片山西好医生药业有限公司42二维葡钙片山西好医生药业有限公司43口服五维葡萄糖山西好医生药业有限公司44克拉霉素胶囊山西好医生药业有限公司45阿普唑仑片太原市振兴制药有限责任公司46地西泮片太原市振兴制药有限责任公司47硝酸异山梨酯片太原市振兴制药有限责任公司48男康片山西旺龙药业集团有限公司49猴头健胃灵胶囊山西旺龙药业集团有限公司50藤黄健骨丸山西旺龙药业集团有限公司51参苓白术颗粒山西旺龙药业集团有限公司52三肾丸（岢岚方）山西旺龙药业集团有限公司53龙胆泻肝丸山西万辉制药有限公司54朱砂安神丸山西万辉制药有限公司55金匮肾气丸山西万辉制药有限公司56柏子养心丸山西万辉制药有限公司57木香顺气丸山西万辉制药有限公司58天王补心丸山西万辉制药有限公司59心脑康胶囊山西万辉制药有限公司60香砂养胃丸山西万辉制药有限公司61天麻丸山西万辉制药有限公司62人参健脾丸山西万辉制药有限公司63知柏地黄丸山西万辉制药有限公司64明目地黄丸山西万辉制药有限公司65附子理中丸山西万辉制药有限公司66舒肝健胃丸山西万辉制药有限公司67黄连上清丸山西万辉制药有限公司68四消丸山西万辉制药有限公司69参梅养胃颗粒山西万辉制药有限公司70银翘解毒丸山西万辉制药有限公司71逍遥丸山西万辉制药有限公司72人参养荣丸山西万辉制药有限公司73健脾丸广盛原中医药有限公司74启脾丸广盛原中医药有限公司75安宫牛黄丸山西广誉远国药有限公司76龟龄集山西广誉远国药有限公司77牛黄清心丸（局方）山西广誉远国药有限公司78定坤丹山西广誉远国药有限公司79定坤丹（水蜜丸）山西广誉远国药有限公司80定坤丹口服液山西广誉远国药有限公司81加味龟龄集酒山西广誉远国药有限公司82利奈唑胺片云鹏医药集团有限公司83盐酸普萘洛尔片云鹏医药集团有限公司84硝苯地平缓释片（II）云鹏医药集团有限公司85氨茶碱片山西太原药业有限公司86诺氟沙星胶囊山西太原药业有限公司87氨茶碱注射液山西太原药业有限公司88布洛芬片山西太原药业有限公司89二羟丙茶碱注射液山西太原药业有限公司90盐酸普萘洛尔片亚宝药业集团股份有限公司91诺氟沙星胶囊亚宝药业集团股份有限公司92普瑞巴林胶囊亚宝药业集团股份有限公司93硝苯地平控释片山西同达药业有限公司94苯磺酸氨氯地平片山西同达药业有限公司95培哚普利氨氯地平片（I）山西同达药业有限公司96盐酸二甲双胍缓释片山西同达药业有限公司97沙格列汀二甲双胍缓释片（I）山西同达药业有限公司98对乙酰氨基酚片山西同达药业有限公司99复方氨酚烷胺胶囊山西同达药业有限公司100氨咖黄敏胶囊山西同达药业有限公司101布洛芬片山西同达药业有限公司102依托考昔片山西同达药业有限公司103硫酸氨基葡萄糖胶囊山西同达药业有限公司104布洛芬缓释胶囊山西同达药业有限公司105缬沙坦氨氯地平片(II)山西德元堂药业有限公司106盐酸莫西沙星片山西德元堂药业有限公司107富马酸比索洛尔片山西德元堂药业有限公司108阿托伐他汀钙片山西德元堂药业有限公司109吲哚布芬片山西德元堂药业有限公司110依折麦布阿托伐他汀钙片(I)山西德元堂药业有限公司111达格列净片山西德元堂药业有限公司112硫酸氨基葡萄糖胶囊山西德元堂药业有限公司113替米沙坦氨氯地平片山西德元堂药业有限公司114替米沙坦氨氯地平片(II)山西德元堂药业有限公司115奥美沙坦酯氨氯地平片山西德元堂药业有限公司116补中益气丸山西华康药业股份有限公司117附子理中丸山西华康药业股份有限公司118六味地黄丸山西华康药业股份有限公司119六味地黄丸（浓缩丸）山西华康药业股份有限公司120盐酸曲唑酮片沈阳华泰药物研究有限公司121盐酸安非他酮缓释片沈阳福宁药业有限公司122醋酸钙片沈阳福宁药业有限公司123克霉唑阴道泡腾片沈阳福宁药业有限公司124硫酸羟氯喹片沈阳欣瑞制药有限公司125替硝唑阴道片沈阳欣瑞制药有限公司126枸橼酸氢钾钠颗粒沈阳华泰药物研究有限公司127碳酸镧咀嚼片沈阳华泰药物研究有限公司128枸橼酸坦度螺酮片沈阳华泰药物研究有限公司129马来酸氟伏沙明片沈阳华泰药物研究有限公司130姜枣祛寒颗粒沈阳清宫药业集团有限公司131人参归脾丸沈阳清宫药业集团有限公司132大山楂丸沈阳清宫药业集团有限公司133壮腰健肾丸沈阳清宫药业集团有限公司134六味地黄丸（浓缩丸）沈阳清宫药业集团有限公司135氟康唑胶囊辉瑞制药科技有限公司136气滞胃痛颗粒本溪国家中成药工程技术研究中心有限公司137气滞胃痛片辽宁华润本溪三药有限公司138尪痹胶囊辽宁华润本溪三药有限公司139瘀血痹片辽宁华润本溪三药有限公司140痢特敏胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司141盐酸非索非那定片黑龙江乌苏里江制药有限公司哈尔滨分公司142左羟丙哌嗪分散片黑龙江乌苏里江制药有限公司哈尔滨分公司143板蓝根颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司144愈伤灵胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司145北豆根胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司146参茸片黑龙江乌苏里江制药有限公司哈尔滨分公司147感冒退热颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司148银花感冒颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司149牛黄消炎片黑龙江乌苏里江制药有限公司哈尔滨分公司150复方金银花颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司151复方羊角片黑龙江乌苏里江制药有限公司哈尔滨分公司152消炎退热颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司153人工牛黄甲硝唑胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司154左羟丙哌嗪胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司155穿心莲分散片黑龙江乌苏里江制药有限公司哈尔滨分公司156妇康宁片黑龙江乌苏里江制药有限公司哈尔滨分公司157精制冠心片黑龙江乌苏里江制药有限公司哈尔滨分公司158刺五加片黑龙江乌苏里江制药有限公司哈尔滨分公司159乳酸菌素片黑龙江乌苏里江制药有限公司哈尔滨分公司160骨折挫伤胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司161复方羊角颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司162决明平脂胶囊黑龙江乌苏里江制药有限公司哈尔滨分公司163西洛他唑片黑龙江乌苏里江制药有限公司哈尔滨分公司164利胆排石片黑龙江乌苏里江制药有限公司哈尔滨分公司165银黄颗粒黑龙江乌苏里江制药有限公司哈尔滨分公司166西黄丸龙晖药业有限公司167参茸安神丸龙晖药业有限公司168利培酮口崩片兰西哈三联制药有限公司169螺内酯片上海上药信谊药厂有限公司170地高辛片上海上药信谊药厂有限公司171盐酸普罗帕酮片上海上药信谊药厂有限公司172氯氮平片上海上药信谊药厂有限公司173二羟丙茶碱片上海上药信谊药厂有限公司174法莫替丁片上海上药信谊药厂有限公司175奥美拉唑碳酸氢钠干混悬剂（II）上海上药信谊药厂有限公司176利多卡因气雾剂上海上药信谊药厂有限公司177茶苯海明片上海上药信谊药厂有限公司178盐酸美西律片上海上药信谊药厂有限公司179盐酸倍他司汀片上海上药信谊药厂有限公司180尼美舒利分散片上海云峰药业有限公司181盐酸雷尼替丁胶囊上海云峰药业有限公司182苯磺酸左氨氯地平片扬子江药业集团上海海尼药业有限公司183头孢克洛分散片上海金城素智药业有限公司184左氧氟沙星片上海金城素智药业有限公司185头孢羟氨苄干混悬剂上海金城素智药业有限公司186复方木香铝镁片上海金城素智药业有限公司187头孢氨苄干混悬剂上海金城素智药业有限公司188头孢地尼干混悬剂上海金城素智药业有限公司189注射用头孢唑林钠上海金城素智药业有限公司190注射用头孢噻肟钠上海金城素智药业有限公司191注射用头孢他啶上海金城素智药业有限公司192拉考沙胺口服溶液上海上药第一生化药业有限公司193拉考沙胺片上海上药第一生化药业有限公司194卡马西平片上海复旦复华药业有限公司195复方聚乙二醇电解质散（Ⅲ）翎耀生物科技（上海）有限公司196复方聚乙二醇（3350）电解质散翎耀生物科技（上海）有限公司197缬沙坦氨氯地平片（Ⅰ）翎耀生物科技（上海）有限公司198依折麦布片翎耀生物科技（上海）有限公司199瑞舒伐他汀钙片翎耀生物科技（上海）有限公司200泊沙康唑肠溶片上海宣泰医药科技股份有限公司201碳酸司维拉姆片上海宣泰医药科技股份有限公司202奥拉帕利片上海宣泰医药科技股份有限公司203乳酸环丙沙星阴道泡腾片上海桓华制药有限公司204胃脘舒颗粒上海宝龙药业股份有限公司205西咪替丁片上海宝龙药业股份有限公司206复方营养混悬剂上海宝龙药业股份有限公司207依非韦伦片上海迪赛诺医药集团股份有限公司208拉米夫定片上海迪赛诺医药集团股份有限公司209奈韦拉平齐多拉米双夫定片上海迪赛诺医药集团股份有限公司210盐酸左氧氟沙星胶囊上海迪赛诺医药集团股份有限公司211昂丹司琼口溶膜上海欣峰制药有限公司212氟尿嘧啶注射液上海旭东海普药业有限公司213米力农注射液上海旭东海普药业有限公司214玻璃酸钠滴眼液上海信谊金朱药业有限公司215吡哌酸片上海信谊万象药业股份有限公司216克拉霉素片上海雅培制药有限公司217甲磺酸阿帕替尼片江苏恒瑞医药股份有限公司218海曲泊帕乙醇胺片江苏恒瑞医药股份有限公司219艾瑞昔布片江苏恒瑞医药股份有限公司220磷酸瑞格列汀片江苏恒瑞医药股份有限公司221贝前列素钠片昆山龙灯瑞迪制药有限公司222培唑帕尼片昆山龙灯瑞迪制药有限公司223达可替尼片昆山龙灯瑞迪制药有限公司224罗沙司他胶囊昆山龙灯瑞迪制药有限公司225苯溴马隆胶囊昆山龙灯瑞迪制药有限公司226盐酸罗匹尼罗缓释片昆山龙灯瑞迪制药有限公司227瑞舒伐他汀钙片常州制药厂有限公司228阿哌沙班片常州制药厂有限公司229硝苯地平控释片常州制药厂有限公司230沙库巴曲缬沙坦钠片常州制药厂有限公司231磷酸西格列汀片常州制药厂有限公司232盐酸鲁拉西酮片常州制药厂有限公司233氢氯噻嗪片常州制药厂有限公司234马来酸依那普利片常州制药厂有限公司235卡托普利片常州制药厂有限公司236苯磺酸氨氯地平片常州制药厂有限公司237氯氮平片常州制药厂有限公司238沙库巴曲缬沙坦钠片江苏华瀚医药科技有限公司239达格列净片南京方生和医药科技有限公司240碳酸镧咀嚼片南京正大天晴制药有限公司241地奥司明片南京正大天晴制药有限公司242西格列汀二甲双胍缓释片南京正大天晴制药有限公司243六神丸雷允上药业集团有限公司244珍菊降压片雷允上药业集团有限公司245六味地黄丸（浓缩丸）雷允上药业集团有限公司246首乌丸雷允上药业集团有限公司247苏合香丸雷允上药业集团有限公司248香菊感冒颗粒雷允上药业集团有限公司249健延龄胶囊雷允上药业集团有限公司250和络舒肝胶囊雷允上药业集团有限公司251六神胶囊雷允上药业集团有限公司252二至丸雷允上药业集团有限公司253灵芝胶囊雷允上药业集团有限公司254牛黄消炎丸雷允上药业集团有限公司255吊筋药雷允上药业集团有限公司256制金柑丸雷允上药业集团有限公司257黄蛭益肾胶囊雷允上药业集团有限公司258参苓白术丸雷允上药业集团有限公司259三妙丸雷允上药业集团有限公司260越鞠丸雷允上药业集团有限公司261富马酸丙酚替诺福韦片苏州弘森药业股份有限公司262达格列净片江苏万高药业股份有限公司263沙格列汀二甲双胍缓释片（Ⅰ）江苏万高药业股份有限公司264沙格列汀二甲双胍缓释片（Ⅲ）江苏万高药业股份有限公司265奥美沙坦酯氨氯地平片江苏万高药业股份有限公司266依折麦布阿托伐他汀钙片（Ⅰ）江苏万高药业股份有限公司267阿仑膦酸钠片江苏万高药业股份有限公司268奥美沙坦酯氢氯噻嗪片江苏万高药业股份有限公司269马来酸氟伏沙明片江苏万高药业股份有限公司270非诺贝特酸胆碱缓释胶囊江苏万高药业股份有限公司271普瑞巴林胶囊德全药品(江苏)股份有限公司272氯氮平片江苏云阳集团药业有限公司273盐酸莫西沙星片扬子江药业集团江苏紫龙药业有限公司274骨化三醇软胶囊南京海鲸药业股份有限公司275维格列汀片江苏豪森药业集团有限公司276沙格列汀片江苏豪森药业集团有限公司277恩格列净片江苏豪森药业集团有限公司278瑞格列奈片江苏豪森药业集团有限公司279艾米替诺福韦片江苏豪森药业集团有限公司280培莫沙肽注射液江苏豪森药业集团有限公司281盐酸莫西沙星片宁波美诺华天康药业有限公司282富马酸丙酚替诺福韦片宁波美诺华天康药业有限公司283左乙拉西坦缓释片宁波美诺华天康药业有限公司284达格列净片宁波美诺华天康药业有限公司285螺内酯片杭州民生药业股份有限公司286双氯芬酸钠缓释片浙江迪耳药业有限公司287盐酸达泊西汀片浙江施强制药有限公司288缬沙坦氢氯噻嗪片浙江英格莱制药有限公司289西格列汀二甲双胍片（II）浙江英格莱制药有限公司290西格列汀二甲双胍缓释片浙江昂利康制药股份有限公司291恩格列净二甲双胍缓释片（II）浙江昂利康制药股份有限公司292沙库巴曲缬沙坦钠片浙江昂利康制药股份有限公司293酒石酸伐尼克兰片杭州民生健康药业股份有限公司294克立硼罗软膏杭州朱养心药业有限公司295二甲双胍恩格列净片（Ⅲ）杭州朱养心药业有限公司296阿仑膦酸钠片杭州民生滨江制药有限公司297二甲双胍恩格列净片（Ⅰ）浙江易泽达医药科技有限公司298西格列汀二甲双胍片(Ⅰ)浙江易泽达医药科技有限公司299西格列汀二甲双胍片(Ⅱ)浙江易泽达医药科技有限公司300富马酸替诺福韦二吡呋酯片杭州和泽坤元药业有限公司301瑞巴派特片浙江大冢制药有限公司302草酸艾司西酞普兰口服溶液浙江国镜药业有限公司303复方聚乙二醇电解质散（Ⅲ）浙江国镜药业有限公司304人参健脾片浙江维康药业股份有限公司305盐酸罗格列酮片浙江海正药业股份有限公司306他克莫司胶囊浙江海正药业股份有限公司307比卡鲁胺片浙江海正药业股份有限公司308丁二磺酸腺苷蛋氨酸肠溶片浙江海正药业股份有限公司309拉考沙胺片浙江华海药业股份有限公司310富马酸喹硫平片浙江华海药业股份有限公司311富马酸喹硫平缓释片浙江华海药业股份有限公司312马来酸依那普利片浙江华海药业股份有限公司313替米沙坦片浙江华海药业股份有限公司314奥美沙坦酯氨氯地平片浙江华海药业股份有限公司315卡格列净片浙江华海药业股份有限公司316盐酸托莫西汀胶囊浙江华海药业股份有限公司317百令颗粒杭州中美华东制药有限公司318马来酸美凡厄替尼片杭州中美华东制药有限公司319阿莫西林胶囊浙江亚峰药厂有限公司320阿莫西林舒巴坦匹酯片浙江亚峰药厂有限公司321阿莫西林克拉维酸钾分散片浙江亚峰药厂有限公司322普瑞巴林胶囊浙江诺得药业有限公司323利伐沙班片浙江诺得药业有限公司324替米沙坦片安徽贤桂医药科技有限公司325驱虫斑鸠菊注射液芜湖杨燕制药有限公司326盐酸奥普力农注射液芜湖杨燕制药有限公司327氨氯地平阿托伐他汀钙片福建海西新药创制股份有限公司328缬沙坦氨氯地平片(I)福建海西新药创制股份有限公司329缬沙坦片福建海西新药创制股份有限公司330塞来昔布胶囊福建海西新药创制股份有限公司331比索洛尔氨氯地平片福建海西新药创制股份有限公司332盐酸贝尼地平片福建海西新药创制股份有限公司333尼麦角林片福建海西新药创制股份有限公司334山楂精降脂片福建汇天生物药业有限公司335复方马勃水杨酸散福建汇天生物药业有限公司336一清颗粒福建乐尔康药业有限公司337板蓝根颗粒福建乐尔康药业有限公司338慢肝解郁胶囊福建乐尔康药业有限公司339大败毒胶囊福建乐尔康药业有限公司340藿香正气片福建乐尔康药业有限公司341牛黄解毒片福建乐尔康药业有限公司342三黄片福建乐尔康药业有限公司343黄连上清片福建乐尔康药业有限公司344复方丹参片福建乐尔康药业有限公司345兰索拉唑肠溶片福建乐尔康药业有限公司346阿奇霉素片福建乐尔康药业有限公司347盐酸左氧氟沙星胶囊福建乐尔康药业有限公司348克拉霉素胶囊福建乐尔康药业有限公司349复方太子参颗粒福建省闽东力捷迅药业股份有限公司350复方太子参口服液福建省闽东力捷迅药业股份有限公司351法莫替丁钙镁咀嚼片福建省闽东力捷迅药业股份有限公司352氨溴特罗口服溶液福建省闽东力捷迅药业股份有限公司353氢溴酸伏硫西汀片福建省闽东力捷迅药业股份有限公司354吡拉西坦片福建省闽东力捷迅药业股份有限公司355磷酸奥司他韦胶囊福建省闽东力捷迅药业股份有限公司356磷酸奥司他韦干混悬剂福建省闽东力捷迅药业股份有限公司357盐酸曲唑酮片福建省闽东力捷迅药业股份有限公司358胞磷胆碱钠片福建省闽东力捷迅药业股份有限公司359增液口服液福建省闽东力捷迅药业股份有限公司360莲花峰茶福建省南安市莲花峰药厂361布洛芬缓释胶囊福建太平洋制药有限公司362阿昔洛韦乳膏福建太平洋制药有限公司363联苯苄唑乳膏福建太平洋制药有限公司364酞丁安乳膏福建太平洋制药有限公司365酮康唑乳膏福建太平洋制药有限公司366硝酸咪康唑乳膏福建太平洋制药有限公司367复方乳酸乳膏福建太平洋制药有限公司368尿素维E乳膏福建太平洋制药有限公司369维胺酯维E乳膏福建太平洋制药有限公司370曲安奈德益康唑乳膏福建太平洋制药有限公司371咪康唑氯倍他索乳膏福建太平洋制药有限公司372复方倍氯米松樟脑乳膏福建太平洋制药有限公司373曲咪新乳膏福建太平洋制药有限公司374风油精福建太平洋制药有限公司375氯雷他定糖浆福建太平洋制药有限公司376蒙脱石散福建太平洋制药有限公司377布洛芬混悬液福建太平洋制药有限公司378养脾散福建永春制药有限公司379三七胶囊福建永春制药有限公司380灵芝菌合剂福建永燠制药有限公司381胃得安胶囊金陵药业股份有限公司福州梅峰制药厂382胃得安片金陵药业股份有限公司福州梅峰制药厂383氧厦门空分特气实业有限公司384氧（液态）厦门空分特气实业有限公司385拓培非格司亭注射液厦门特宝生物工程股份有限公司386金凤丸同溢堂药业有限公司387五子衍宗丸同溢堂药业有限公司388正红花油万源（福州）药业有限公司389驱风油万源（福州）药业有限公司390复方氨酚烷胺胶囊万源（福州）药业有限公司391盐酸氨溴索口服溶液万源（福州）药业有限公司392风油精漳州水仙药业股份有限公司393夫西地酸乳膏漳州水仙药业股份有限公司394恩格列净片漳州水仙药业股份有限公司395复方倍氯米松樟脑乳膏漳州无极药业有限公司396丁硼乳膏漳州无极药业有限公司397复方硝酸咪康唑软膏漳州无极药业有限公司398片仔癀漳州片仔癀药业股份有限公司399复方片仔癀软膏漳州片仔癀药业股份有限公司400复方片仔癀含片漳州片仔癀药业股份有限公司401茵胆平肝胶囊漳州片仔癀药业股份有限公司402片仔癀胶囊漳州片仔癀药业股份有限公司403金牡感冒片漳州片仔癀药业股份有限公司404川贝清肺糖浆漳州片仔癀药业股份有限公司405藿香正气胶囊漳州片仔癀药业股份有限公司406六味地黄丸厦门中药厂有限公司407香砂六君丸厦门中药厂有限公司408知柏地黄丸厦门中药厂有限公司409六一散厦门中药厂有限公司410灵芝胶囊厦门中药厂有限公司411加减地黄丸厦门中药厂有限公司412杞菊地黄丸厦门中药厂有限公司413六味地黄丸（异型小蜜丸）厦门中药厂有限公司414安宫牛黄丸厦门中药厂有限公司415通脉降脂片厦门中药厂有限公司416通脉降脂胶囊厦门中药厂有限公司417逍遥丸（水丸）厦门中药厂有限公司418补中益气丸(水丸)厦门中药厂有限公司419芪骨胶囊厦门中药厂有限公司420益脑胶囊福州闽海药业有限公司421醒脑再造胶囊福州闽海药业有限公司422回春如意胶囊福州闽海药业有限公司423丹七胶囊福州闽海药业有限公司424泮托拉唑钠肠溶胶囊福州闽海药业有限公司425小儿七星茶颗粒福州闽海药业有限公司426鼻炎宁颗粒福州闽海药业有限公司427伤科跌打片福州闽海药业有限公司428丹七片福州闽海药业有限公司429抗骨增生片福州闽海药业有限公司430痔速宁片福州闽海药业有限公司431复方桔梗止咳片福州闽海药业有限公司432杞菊地黄片福州闽海药业有限公司433三维B片福州闽海药业有限公司434跳骨片福州闽海药业有限公司435塞来昔布胶囊福州闽海药业有限公司436利丙双卡因乳膏山东明仁福瑞达制药股份有限公司437枸橼酸托法替布片山东明仁福瑞达制药股份有限公司438二甲双胍维格列汀片（Ⅱ）齐鲁制药有限公司439二十碳五烯酸乙酯软胶囊齐鲁制药有限公司440阿胶山东宏济堂制药集团股份有限公司441阿司匹林肠溶片山东新华制药股份有限公司442富马酸比索洛尔片山东新华制药股份有限公司443恩格列净片山东新华制药股份有限公司444瑞舒伐他汀钙片山东新华制药股份有限公司445硫酸氢氯吡格雷片山东新华制药股份有限公司446枸橼酸托法替布片山东新华制药股份有限公司447枸橼酸西地那非口崩片济南高华制药有限公司448磷酸西格列汀片济南高华制药有限公司449他达拉非片山东罗欣药业集团股份有限公司450替格瑞洛片山东罗欣药业集团股份有限公司451二甲双胍恩格列净片（I）烟台鲁银药业有限公司452恩格列净片烟台鲁银药业有限公司453硝苯地平控释片烟台鲁银药业有限公司454匹伐他汀钙片烟台鲁银药业有限公司455他达拉非片烟台鲁银药业有限公司456琥珀酸美托洛尔缓释胶囊烟台鲁银药业有限公司457单硝酸异山梨酯片瑞阳制药股份有限公司458盐酸左西替利嗪片瑞阳制药股份有限公司459硫酸氨基葡萄糖胶囊瑞阳制药股份有限公司460二甲双胍格列本脲胶囊(Ⅰ)瑞阳制药股份有限公司461中性蛋白酶肠溶片瑞阳制药股份有限公司462盐酸特比萘芬阴道泡腾片瑞阳制药股份有限公司463氯化钾片瑞阳制药股份有限公司464格列吡嗪片瑞阳制药股份有限公司465富马酸卢帕他定片瑞阳制药股份有限公司466马来酸阿伐曲泊帕片瑞阳制药股份有限公司467阿昔洛韦片瑞阳制药股份有限公司468盐酸美金刚片瑞阳制药股份有限公司469尼群地平片瑞阳制药股份有限公司470达可替尼片瑞阳制药股份有限公司471厚朴排气合剂瑞阳制药股份有限公司472西红花总苷片瑞阳制药股份有限公司473血塞通分散片瑞阳制药股份有限公司474头孢呋辛酯片瑞阳制药股份有限公司475阿莫西林胶囊瑞阳制药股份有限公司476苯唑西林钠胶囊瑞阳制药股份有限公司477阿莫西林克拉维酸钾片瑞阳制药股份有限公司478苯唑西林钠片瑞阳制药股份有限公司479盐酸二甲双胍缓释片山东汇泽生物制药有限公司480苯磺酸氨氯地平片山东方明药业集团股份有限公司481盐酸吡格列酮胶囊山东淄博新达制药有限公司482非布司他片山东淄博新达制药有限公司483非那雄胺片山东淄博新达制药有限公司484丙戊酸钠口服溶液山东京卫制药有限公司485己酮可可碱缓释片山东京卫制药有限公司486布南色林片山东京卫制药有限公司487吲哚布芬片山东京卫制药有限公司488复方硫酸氢黄连素软膏山东丰寅盛达药业有限公司489氟康唑片山东齐都药业有限公司490盐酸左氧氟沙星片山东齐都药业有限公司491阿昔洛韦片山东齐都药业有限公司492碳酸镧咀嚼片山东齐都药业有限公司493吡格列酮二甲双胍片(15mg/500mg)山东齐都药业有限公司494沙格列汀二甲双胍缓释片（I）山东齐都药业有限公司495比索洛尔氨氯地平片山东齐都药业有限公司496替米沙坦氨氯地平片山东齐都药业有限公司497奥美拉唑碳酸氢钠干混悬剂(Ⅰ)山东齐都药业有限公司498硫酸镁钠钾口服用浓溶液山东齐都药业有限公司499盐酸环丙沙星片山东齐都药业有限公司500氧氟沙星片山东齐都药业有限公司501醋酸甲地孕酮分散片青岛国海生物制药有限公司502盐酸乙哌立松片青岛国海生物制药有限公司503马来酸依那普利口腔崩解片青岛国海生物制药有限公司504对乙酰氨基酚干混悬剂青岛国海生物制药有限公司505维参锌胶囊青岛国海生物制药有限公司506聚苯乙烯磺酸钙散青岛国海生物制药有限公司507吲达帕胺片烟台巨先药业有限公司508酒石酸美托洛尔片烟台巨先药业有限公司509酒石酸伐尼克兰片山东威智百科药业有限公司510恒格列净二甲双胍缓释片(I)山东盛迪医药有限公司511恒格列净二甲双胍缓释片(II)山东盛迪医药有限公司512头孢克肟片湖南方盛制药股份有限公司513头孢丙烯片湖南方盛制药股份有限公司514依折麦布片湖南方盛制药股份有限公司515厄贝沙坦氢氯噻嗪片湖南方盛制药股份有限公司516蒙脱石散湖南方盛制药股份有限公司517奥美拉唑肠溶片湖南方盛制药股份有限公司518奥硝唑片湖南方盛制药股份有限公司519赖氨酸维B12颗粒湖南方盛制药股份有限公司520小儿氨酚黄那敏颗粒湖南方盛制药股份有限公司521奥硝唑阴道栓湖南方盛制药股份有限公司522口服五维赖氨酸葡萄糖湖南方盛制药股份有限公司523人工牛黄甲硝唑胶囊湖南方盛制药股份有限公司524铝碳酸镁咀嚼片湖南方盛制药股份有限公司525小儿复方四维亚铁散湖南方盛制药股份有限公司526二维亚铁颗粒湖南方盛制药股份有限公司527维生素C颗粒湖南方盛制药股份有限公司528牡蛎碳酸钙颗粒湖南方盛制药股份有限公司529依托红霉素颗粒湖南方盛制药股份有限公司530克拉霉素胶囊湖南方盛制药股份有限公司531骨化三醇软胶囊湖南银泽华浩生物科技有限公司532艾司奥美拉唑镁肠溶胶囊湖南银泽华浩生物科技有限公司533阿托伐他汀钙片湖南千金湘江药业股份有限公司534富马酸丙酚替诺福韦片湖南千金湘江药业股份有限公司535马来酸氟伏沙明片湖南千金湘江药业股份有限公司536盐酸达泊西汀片湖南千金湘江药业股份有限公司537阿哌沙班片湖南千金湘江药业股份有限公司538多巴丝肼片湖南千金湘江药业股份有限公司539酒石酸唑吡坦片湖南千金湘江药业股份有限公司540拉米夫定片湖南千金湘江药业股份有限公司541马来酸依那普利片湖南千金湘江药业股份有限公司542诺氟沙星胶囊湖南千金湘江药业股份有限公司543缬沙坦胶囊湖南千金湘江药业股份有限公司544盐酸贝那普利片湖南千金湘江药业股份有限公司545左乙拉西坦片湖南千金湘江药业股份有限公司546他达拉非片湖南千金湘江药业股份有限公司547富马酸替诺福韦二吡呋酯片湖南千金湘江药业股份有限公司548替格瑞洛片湖南千金湘江药业股份有限公司549恩格列净片湖南千金湘江药业股份有限公司550碳酸锂片湖南千金湘江药业股份有限公司551苯甲酸阿格列汀片湖南千金湘江药业股份有限公司552富马酸伏诺拉生片湖南千金湘江药业股份有限公司553沙库巴曲缬沙坦钠片湖南千金协力药业有限公司554伊曲康唑口服液嘉实（湖南）医药科技有限公司555古汉养生精颗粒古汉中药有限公司556天麻首乌片湖南德海制药有限公司557天麻首乌胶囊湖南德海制药有限公司558降脂灵片湖南德海制药有限公司559硝酸奥昔康唑乳膏湖南中威制药有限公司560那氟沙星乳膏湖南中威制药有限公司561米诺地尔搽剂江右制药（常德）有限公司562妇康宝口服液江右制药（常德）有限公司563龙胆泻肝丸江右制药（常德）有限公司564护肝片江右制药（常德）有限公司565栀子金花丸江右制药（常德）有限公司566长春宝丸江右制药（常德）有限公司567长春宝口服液江右制药（常德）有限公司568安宫牛黄丸江右制药（常德）有限公司569独一味分散片江右制药（常德）有限公司570酒石酸美托洛尔片湖南威特制药股份有限公司571替米沙坦片湖南威特制药股份有限公司572他达拉非片湖南威特制药股份有限公司573氨氯地平阿托伐他汀钙片湖南威特制药股份有限公司574磷酸西格列汀片湖南威特制药股份有限公司575六味地黄丸（浓缩丸）湖南状元制药有限公司576杞菊地黄丸（浓缩丸）湖南状元制药有限公司577苯磺酸氨氯地平片湖南状元制药有限公司578硫辛酸片湖南先施制药有限公司579磷酸奥司他韦颗粒湖南先施制药有限公司580玻璃酸钠滴眼液湖南先施制药有限公司581复方匹可硫酸钠颗粒辉凌制药（中国）有限公司582氯化钾缓释片广州誉东健康制药有限公司583西格列汀二甲双胍缓释片广州誉东健康制药有限公司584枸橼酸西地那非片广州祺楠药业科技有限责任公司585艾地苯醌片深圳海王药业有限公司586小儿氨酚黄那敏颗粒深圳海王药业有限公司587盐酸二甲双胍片深圳海王药业有限公司588阿昔洛韦片深圳海王药业有限公司589阿奇霉素片深圳海王药业有限公司590枸橼酸西地那非片深圳海王药业有限公司591盐酸二甲双胍缓释片恒昌（广州）新药研究有限公司592酒石酸美托洛尔片恒昌（广州）新药研究有限公司593地氯雷他定口服溶液恒昌（广州）新药研究有限公司594孟鲁司特钠咀嚼片恒昌（广州）新药研究有限公司595阿卡波糖片恒昌（广州）新药研究有限公司596阿司匹林肠溶片恒昌（广州）新药研究有限公司597磷酸奥司他韦干混悬剂恒昌（广州）新药研究有限公司598非那雄胺分散片恒昌（广州）新药研究有限公司599阿托伐他汀钙片恒昌（广州）新药研究有限公司600枸橼酸西地那非口崩片恒昌（广州）新药研究有限公司601川贝清肺膏恒昌（广州）新药研究有限公司602川贝清肺糖浆恒昌（广州）新药研究有限公司603龟鹿宁神丸恒昌（广州）新药研究有限公司604马来酸依那普利叶酸片深圳奥萨制药有限公司605氨氯地平叶酸片（I）深圳奥萨制药有限公司606氨氯地平叶酸片（II）深圳奥萨制药有限公司607氯氮平片广东彼迪药业有限公司608辛伐他汀片广东彼迪药业有限公司609别嘌醇片广东彼迪药业有限公司610盐酸左氧氟沙星片广东彼迪药业有限公司611利伐沙班口崩片广东粤和泽药物研究有限公司612精蛋白人胰岛素注射液珠海联邦制药股份有限公司中山分公司613人胰岛素注射液珠海联邦制药股份有限公司中山分公司614精蛋白人胰岛素混合注射液（30R）珠海联邦制药股份有限公司中山分公司615精蛋白人胰岛素混合注射液（50R）珠海联邦制药股份有限公司中山分公司616盐酸左氧氟沙星胶囊珠海联邦制药股份有限公司中山分公司617中风回春丸广州白云山敬修堂药业股份有限公司618追风透骨丸广州白云山敬修堂药业股份有限公司619麝香跌打风湿膏广州白云山敬修堂药业股份有限公司620坎地沙坦酯片广州白云山天心制药股份有限公司621酒石酸美托洛尔缓释片（Ⅱ）广州白云山天心制药股份有限公司622左乙拉西坦片深圳信立泰药业股份有限公司623枸橼酸西地那非口崩片金鸿药业股份有限公司624他达拉非片金鸿药业股份有限公司625龟鹿二胶丸广州白云山敬修堂药业股份有限公司626补肾填精丸广州白云山敬修堂药业股份有限公司627盐酸左氧氟沙星胶囊广东逸舒制药股份有限公司628盐酸舍曲林片广东逸舒制药股份有限公司629阿奇霉素颗粒广东逸舒制药股份有限公司630奥美拉唑肠溶胶囊广东逸舒制药股份有限公司631非那雄胺片广东逸舒制药股份有限公司632克拉霉素片广东逸舒制药股份有限公司633氟康唑胶囊广东逸舒制药股份有限公司634氨糖美辛肠溶片广东逸舒制药股份有限公司635盐酸芬戈莫德胶囊广东东阳光药业股份有限公司636小柴胡颗粒广州白云山光华制药股份有限公司637脑络通胶囊广州白云山光华制药股份有限公司638格列齐特片广州白云山光华制药股份有限公司639茶碱缓释片广州白云山光华制药股份有限公司640知柏地黄颗粒广州白云山光华制药股份有限公司641力加寿片广州白云山光华制药股份有限公司642氨酚咖那敏片广州白云山光华制药股份有限公司643胶体果胶铋胶囊广州白云山光华制药股份有限公司644维生素C咀嚼片广州白云山光华制药股份有限公司645氨苯砜片广州白云山光华制药股份有限公司646氨酚待因片(Ⅰ)广州白云山光华制药股份有限公司647枇杷止咳颗粒广州白云山光华制药股份有限公司648复方血栓通软胶囊广东华南药业集团有限公司649羧甲司坦口服溶液广东众生药业股份有限公司650复方丹参片广东众生药业股份有限公司651利多卡因氯己定气雾剂广东同德药业有限公司652他达拉非片广州华圣制药有限公司653地氯雷他定片广州华圣制药有限公司654盐酸非索非那定胶囊国药集团广东环球制药有限公司655烟酸缓释胶囊国药集团广东环球制药有限公司656枸橼酸西地那非片广东泉新泉益药业有限公司657盐酸达泊西汀片广东泉新泉益药业有限公司658他达拉非片广东泉新泉益药业有限公司659米诺地尔搽剂广东泉新泉益药业有限公司660外用重组人碱性成纤维细胞生长因子朗肽生物制药股份有限公司661头孢克肟干混悬剂深圳立健药业有限公司662头孢克肟片深圳立健药业有限公司663头孢地尼胶囊深圳立健药业有限公司664头孢呋辛酯胶囊深圳立健药业有限公司665头孢克洛片深圳立健药业有限公司666头孢克洛胶囊深圳立健药业有限公司667头孢克洛颗粒深圳立健药业有限公司668头孢丙烯干混悬剂深圳立健药业有限公司669归芍地黄丸广州白云山花城药业有限公司670生脉饮广州白云山花城药业有限公司671壮腰健肾口服液广州白云山花城药业有限公司672阿咖酚散广州白云山医药集团股份有限公司白云山何济公制药厂673他达拉非片广东彼迪药业有限公司674奥美沙坦酯氨氯地平片珠海润都制药股份有限公司675单硝酸异山梨酯片珠海润都制药股份有限公司676厄贝沙坦片珠海润都制药股份有限公司677缬沙坦氨氯地平片（I）珠海润都制药股份有限公司678盐酸伐昔洛韦片珠海润都制药股份有限公司679盐酸莫西沙星片珠海润都制药股份有限公司680沙库巴曲缬沙坦钠片珠海润都制药股份有限公司681银杏叶片深圳海王药业有限公司682盐酸氟桂利嗪胶囊深圳海王药业有限公司683盐酸黄酮哌酯片深圳海王药业有限公司684格列齐特片深圳海王药业有限公司685氯雷他定胶囊深圳海王药业有限公司686氯雷他定咀嚼片深圳海王药业有限公司687富马酸伏诺拉生片广东东阳光药业股份有限公司688吡拉西坦注射液珠海和凡医药股份有限公司689非布司他片珠海和凡医药股份有限公司690拉米夫定片珠海和凡医药股份有限公司691吡拉西坦氯化钠注射液珠海和凡医药股份有限公司692阿苯达唑颗粒广东南国药业有限公司693阿苯达唑片广东南国药业有限公司694阿咖酚散广东南国药业有限公司695阿普唑仑片广东南国药业有限公司696阿托品异丙嗪注射液广东南国药业有限公司697艾司唑仑片广东南国药业有限公司698氨咖黄敏胶囊广东南国药业有限公司699板蓝根颗粒广东南国药业有限公司700板蓝根注射液广东南国药业有限公司701贝诺酯片广东南国药业有限公司702苯甲酸苄酯搽剂广东南国药业有限公司703吡拉西坦胶囊广东南国药业有限公司704丙谷胺片广东南国药业有限公司705布洛芬片广东南国药业有限公司706苍莲感冒片广东南国药业有限公司707刺五加片广东南国药业有限公司708醋酸可的松滴眼液广东南国药业有限公司709醋酸泼尼松片广东南国药业有限公司710大黄碳酸氢钠片广东南国药业有限公司711地塞米松片广东南国药业有限公司712地西泮片广东南国药业有限公司713地西泮注射液广东南国药业有限公司714碘酊广东南国药业有限公司715对乙酰氨基酚口服溶液广东南国药业有限公司716对乙酰氨基酚片广东南国药业有限公司717风油精广东南国药业有限公司718呋塞米注射液广东南国药业有限公司719复方氨林巴比妥注射液广东南国药业有限公司720复方穿心莲片广东南国药业有限公司721复方丹参片广东南国药业有限公司722复方甘草口服溶液广东南国药业有限公司723复方甘草片广东南国药业有限公司724复方感冒灵片广东南国药业有限公司725复方岗稔片广东南国药业有限公司726复方黄连素片广东南国药业有限公司727复方磺胺甲噁唑片广东南国药业有限公司728复方磺胺甲噁唑注射液广东南国药业有限公司729复方桔梗麻黄碱糖浆(Ⅱ)广东南国药业有限公司730复方南板蓝根片广东南国药业有限公司731复方愈创木酚磺酸钾口服溶液广东南国药业有限公司732复合维生素B片广东南国药业有限公司733感冒清片广东南国药业有限公司734枸橼酸喷托维林片广东南国药业有限公司735枸橼酸铁铵维B1糖浆Ⅱ广东南国药业有限公司736过氧化氢溶液广东南国药业有限公司737咳特灵胶囊广东南国药业有限公司738咳特灵片广东南国药业有限公司739喉舒宁片广东南国药业有限公司740磺胺嘧啶钠注射液广东南国药业有限公司741藿香正气水广东南国药业有限公司742肌醇烟酸酯片广东南国药业有限公司743肌苷口服溶液广东南国药业有限公司744肌苷片广东南国药业有限公司745肌苷注射液广东南国药业有限公司746甲硝唑片广东南国药业有限公司747甲紫溶液广东南国药业有限公司748聚肌胞注射液广东南国药业有限公司749聚维酮碘溶液广东南国药业有限公司750利巴韦林滴眼液广东南国药业有限公司751利巴韦林注射液广东南国药业有限公司752联苯双酯胶囊广东南国药业有限公司753联苯双酯片广东南国药业有限公司754硫酸阿米卡星注射液广东南国药业有限公司755硫酸阿托品片广东南国药业有限公司756硫酸阿托品注射液广东南国药业有限公司757硫酸卡那霉素注射液广东南国药业有限公司758硫酸罗通定注射液广东南国药业有限公司759硫酸庆大霉素注射液广东南国药业有限公司760炉甘石洗剂广东南国药业有限公司761罗通定片广东南国药业有限公司762马来酸氯苯那敏片广东南国药业有限公司763马来酸氯苯那敏注射液广东南国药业有限公司764灭菌注射用水广东南国药业有限公司765萘普生片广东南国药业有限公司766尼群地平片广东南国药业有限公司767牛黄解毒片广东南国药业有限公司768牛磺酸滴眼液广东南国药业有限公司769浓维磷糖浆广东南国药业有限公司770喷托维林氯化铵糖浆广东南国药业有限公司771葡醛内酯片广东南国药业有限公司772葡萄糖注射液广东南国药业有限公司773普瑞巴林口服溶液广东南国药业有限公司774氢化可的松片广东南国药业有限公司775氢化可的松注射液广东南国药业有限公司776清热祛湿颗粒广东南国药业有限公司777乳酸钙片广东南国药业有限公司778乳酸依沙吖啶溶液广东南国药业有限公司779三磷酸腺苷二钠片广东南国药业有限公司780三磷酸腺苷二钠注射液广东南国药业有限公司781十滴水广东南国药业有限公司782羧甲司坦片广东南国药业有限公司783碳酸氢钠片广东南国药业有限公司784天麻素片广东南国药业有限公司785维B1钙咀嚼片广东南国药业有限公司786维生素B12注射液广东南国药业有限公司787维生素B1片广东南国药业有限公司788维生素B1注射液广东南国药业有限公司789维生素B2片广东南国药业有限公司790维生素B6片广东南国药业有限公司791维生素B6注射液广东南国药业有限公司792维生素C片广东南国药业有限公司793维生素C注射液广东南国药业有限公司794五维他口服溶液广东南国药业有限公司795西咪替丁胶囊广东南国药业有限公司796西咪替丁片广东南国药业有限公司797西咪替丁注射液广东南国药业有限公司798小儿止咳糖浆广东南国药业有限公司799烟酰胺注射液广东南国药业有限公司800盐酸川芎嗪注射液广东南国药业有限公司801盐酸多巴酚丁胺注射液广东南国药业有限公司802盐酸林可霉素注射液广东南国药业有限公司803盐酸吗啉胍片广东南国药业有限公司804盐酸莫西沙星滴眼液广东南国药业有限公司805盐酸萘甲唑啉滴鼻液广东南国药业有限公司806盐酸尼卡地平片广东南国药业有限公司807盐酸普罗帕酮片广东南国药业有限公司808盐酸羟苄唑滴眼液广东南国药业有限公司809盐酸小檗碱片广东南国药业有限公司810盐酸乙胺丁醇片广东南国药业有限公司811盐酸异丙嗪注射液广东南国药业有限公司812盐酸左旋咪唑片广东南国药业有限公司813野牡丹止痢片广东南国药业有限公司814紫花杜鹃片广东南国药业有限公司815磷酸奥司他韦胶囊中润药业有限公司816磷酸奥司他韦颗粒中润药业有限公司817枸橼酸西地那非口崩片中润药业有限公司818青梅感冒颗粒广东香山堂制药有限公司819黄地养血口服液广东香山堂制药有限公司820复方消化酶胶囊广东星昊药业有限公司821口炎清颗粒广州白云山和记黄埔中药有限公司822感冒灵颗粒广州白云山和记黄埔中药有限公司823复方板蓝根颗粒广州白云山和记黄埔中药有限公司824丹红化瘀口服液广州白云山和记黄埔中药有限公司825板蓝根颗粒广州白云山和记黄埔中药有限公司826穿心莲片广州白云山和记黄埔中药有限公司827复方穿心莲片广州白云山和记黄埔中药有限公司828感冒清热颗粒广州白云山和记黄埔中药有限公司829橘红痰咳颗粒广州白云山和记黄埔中药有限公司830归芍地黄丸广州白云山和记黄埔中药有限公司831阿莫西林胶囊国药集团汕头金石制药有限公司832缬沙坦胶囊澳美制药（海南）有限公司833蒙脱石散海南先声药业有限公司834苯磺酸左氨氯地平片海南先声药业有限公司835阿莫西林颗粒海南先声药业有限公司836阿莫西林胶囊海南先声药业有限公司837头孢克洛干混悬剂海南先声药业有限公司838阿莫西林克拉维酸干混悬剂海南先声药业有限公司839甘草酸二铵胶囊海南和瑞达药业有限公司840阿瑞匹坦胶囊海南和瑞达药业有限公司841利丙双卡因乳膏海南和瑞达药业有限公司842普瑞巴林胶囊澳美制药（海南）有限公司843左乙拉西坦片澳美制药（海南）有限公司844拉考沙胺片澳美制药（海南）有限公司845维胺酯胶囊重庆华邦制药有限公司846异维A酸软胶囊重庆华邦制药有限公司847阿那曲唑片重庆华邦制药有限公司848盐酸贝尼地平片重庆华邦制药有限公司849多巴丝肼片重庆华邦制药有限公司850喷昔洛韦乳膏重庆华邦制药有限公司851曲安奈德益康唑乳膏重庆华邦制药有限公司852丁酸氢化可的松乳膏重庆华邦制药有限公司853地奈德乳膏重庆华邦制药有限公司854卤米松乳膏重庆华邦制药有限公司855复方樟脑乳膏重庆华邦制药有限公司856他扎罗汀倍他米松乳膏重庆华邦制药有限公司857丙酸氟替卡松乳膏重庆华邦制药有限公司858卡泊三醇倍他米松软膏重庆华邦制药有限公司859糠酸莫米松乳膏重庆华邦制药有限公司860塞来昔布胶囊北大医药股份有限公司861盐酸昂丹司琼片北大医药股份有限公司862盐酸丁螺环酮片北大医药股份有限公司863盐酸帕罗西汀肠溶缓释片北大医药股份有限公司864富马酸丙酚替诺福韦片北大医药股份有限公司865富马酸喹硫平缓释片北大医药股份有限公司866复方磺胺甲噁唑片北大医药股份有限公司867硫酸羟氯喹片重庆博腾药业有限公司868甲钴胺片重庆康刻尔制药股份有限公司869蒲地蓝消炎片重庆陪都药业股份有限公司870舒肝益脾颗粒重庆陪都药业股份有限公司871炎可宁片重庆陪都药业股份有限公司872一清颗粒重庆陪都药业股份有限公司873银黄胶囊重庆陪都药业股份有限公司874冰樟桉氟轻松贴膏重庆陪都药业股份有限公司875精制狗皮膏重庆陪都药业股份有限公司876伤湿祛痛膏重庆陪都药业股份有限公司877麝香壮骨膏重庆陪都药业股份有限公司878壮骨麝香止痛膏重庆陪都药业股份有限公司879复方追风膏重庆陪都药业股份有限公司880独一味泡腾片重庆陪都药业股份有限公司881复方矮地茶胶囊重庆陪都药业股份有限公司882抗菌消炎胶囊重庆陪都药业股份有限公司883心宁胶囊重庆陪都药业股份有限公司884辣椒风湿膏重庆陪都药业股份有限公司885磷酸奥司他韦胶囊四川科伦药业股份有限公司886胶体果胶铋胶囊四川科伦药业股份有限公司887利格列汀片四川科伦药业股份有限公司888芦曲泊帕片四川科伦药业股份有限公司889枸橼酸西地那非口崩片四川科伦药业股份有限公司890普瑞巴林胶囊四川科伦药业股份有限公司891枸橼酸托法替布缓释片四川科伦药业股份有限公司892富马酸伏诺拉生片四川科伦药业股份有限公司893替硝唑片四川科伦药业股份有限公司894甲硝唑片四川科伦药业股份有限公司895罗红霉素片四川科伦药业股份有限公司896恩格列净片四川科伦药业股份有限公司897左氧氟沙星片四川科伦药业股份有限公司898塞来昔布胶囊四川科伦药业股份有限公司899盐酸莫西沙星片四川科伦药业股份有限公司900盐酸左氧氟沙星片四川科伦药业股份有限公司901沙库巴曲缬沙坦钠片四川科伦药业股份有限公司902盐酸莫西沙星片四川国为制药有限公司903骨化三醇软胶囊四川国为制药有限公司904塞来昔布胶囊四川国为制药有限公司905磷酸西格列汀片四川益生智同医药生物科技发展有限公司906地氯雷他定糖浆成都天之翼尚品医药科技有限公司907玄麦甘桔颗粒四川好医生攀西药业有限责任公司908抗感颗粒四川好医生攀西药业有限责任公司909银柴颗粒四川好医生攀西药业有限责任公司910康复新液四川好医生攀西药业有限责任公司911桑姜感冒片四川好医生攀西药业有限责任公司912诺氟沙星胶囊好医生药业集团有限公司913盐酸左氧氟沙星胶囊好医生药业集团有限公司914他达拉非片好医生药业集团有限公司915阿莫西林干混悬剂好医生药业集团有限公司916罗红霉素分散片好医生药业集团有限公司917小儿解表颗粒好医生药业集团有限公司918复方氯唑沙宗胶囊好医生药业集团有限公司919强身健脑片好医生药业集团有限公司920阳春玉液好医生药业集团有限公司921穿黄清热胶囊好医生药业集团有限公司922桑姜感冒胶囊好医生药业集团有限公司923炎可宁片好医生药业集团有限公司924盐酸普拉克索缓释片成都百裕制药股份有限公司925盐酸美金刚片成都百裕制药股份有限公司926兰索拉唑肠溶片扬子江药业集团四川海蓉药业有限公司927左氧氟沙星片四川海汇药业有限公司928全氟己基辛烷滴眼液成都盛迪医药有限公司929比索洛尔氨氯地平片成都硕德药业有限公司930五子衍宗丸太极集团四川绵阳制药有限公司931舒筋活血片太极集团四川绵阳制药有限公司932骨友灵搽剂太极集团四川绵阳制药有限公司933贝前列素钠片成都苑东生物制药股份有限公司934卡培他滨片成都苑东生物制药股份有限公司935奥沙西泮片成都苑东生物制药股份有限公司936盐酸纳呋拉啡口崩片成都苑东生物制药股份有限公司937盐酸阿罗洛尔片成都苑东生物制药股份有限公司938瑞格列奈二甲双胍片（I）成都苑东生物制药股份有限公司939富马酸丙酚替诺福韦片成都苑东生物制药股份有限公司940达比加群酯胶囊成都苑东生物制药股份有限公司941奥氮平片成都苑东生物制药股份有限公司942依托考昔片成都苑东生物制药股份有限公司943硫酸氢氯吡格雷片成都苑东生物制药股份有限公司944乌苯美司胶囊成都苑东生物制药股份有限公司945盐酸美金刚缓释胶囊成都苑东生物制药股份有限公司946拉考沙胺口服溶液成都苑东生物制药股份有限公司947达可替尼片成都苑东生物制药股份有限公司948阿昔替尼片成都苑东生物制药股份有限公司949阿帕他胺片成都苑东生物制药股份有限公司950磷酸芦可替尼片成都苑东生物制药股份有限公司951布瑞哌唑片成都苑东生物制药股份有限公司952妇科再造丸贵州德昌祥医药股份有限公司953杜仲补天素丸贵州德昌祥医药股份有限公司954止嗽化痰丸贵州德昌祥医药股份有限公司955复方梨膏贵州德昌祥医药股份有限公司956安宫牛黄丸贵州德昌祥医药股份有限公司957六味地黄丸（浓缩丸）贵州德昌祥医药股份有限公司958归脾丸（浓缩丸）贵州德昌祥医药股份有限公司959清心明目上清丸贵州德昌祥医药股份有限公司960桂附地黄丸贵州德昌祥医药股份有限公司961逍遥丸贵州德昌祥医药股份有限公司962复方枇杷叶膏贵州德昌祥医药股份有限公司963参茸鞭丸贵州德昌祥医药股份有限公司964补中益气丸贵州德昌祥医药股份有限公司965杞菊地黄丸贵州德昌祥医药股份有限公司966知柏地黄丸贵州德昌祥医药股份有限公司967二陈丸贵州德昌祥医药股份有限公司968石斛夜光丸贵州德昌祥医药股份有限公司969山楂内消丸贵州德昌祥医药股份有限公司970乌鸡白凤丸贵州德昌祥医药股份有限公司971伤科灵喷雾剂华东医药（贵州）药业有限公司972妇科再造胶囊贵州汉方药业有限公司973芪胶升白胶囊贵州汉方药业有限公司974清火养元胶囊贵州汉方药业有限公司975清热散结片贵州汉方药业有限公司976杜仲补天素片贵州汉方药业有限公司977雷公藤多苷片贵州汉方药业有限公司978止嗽定喘片贵州汉方药业有限公司979跌打片贵州汉方药业有限公司980半枝莲片贵州汉方药业有限公司981日舒安洗液贵州汉方药业有限公司982白沙糖浆贵州汉方药业有限公司983肥儿糖浆贵州汉方药业有限公司984天麻灵芝合剂贵州汉方药业有限公司985熊胆滴眼液云南傣药有限公司986萘敏维滴眼液云南傣药有限公司987左氧氟沙星滴眼液云南傣药有限公司988他达拉非片云南先施药业有限公司989利伐沙班片Bayer AG990布瑞哌唑片Otsuka Pharmaceutical Co.，Ltd.991伏立康唑片Pfizer Europe MA EEIG992阿布昔替尼片Pfizer Inc.993哌柏西利胶囊Pfizer Europe MA EEIG994克唑替尼胶囊Pfizer Europe MA EEIG995苹果酸舒尼替尼胶囊Pfizer Europe MA EEIG996枸橼酸托法替布片Pfizer Europe MA EEIG997奈玛特韦片/利托那韦片组合包装Pfizer Europe MA EEIG998瑞舒伐他汀钙片AstraZeneca UK Limited999环硅酸锆钠散AstraZeneca AB1000依西美坦片Pfizer Italia s.r.l.1001沙库巴曲缬沙坦钠片Novartis Pharma Schweiz AG1002缬沙坦氨氯地平片(Ⅰ)Novartis Pharma Schweiz AG1003维格列汀片Novartis Europharm Ltd.1004吸入用布地奈德混悬液AstraZeneca Pty Ltd1005硫酸特布他林吸入溶液AstraZeneca AB1006鲑降钙素鼻用喷雾剂Future Health Pharma GmbH1007那米司特片Boehringer Ingelheim International GmbH1008噻托溴铵吸入喷雾剂Boehringer Ingelheim International GmbH1009噻托溴铵奥达特罗吸入喷雾剂Boehringer Ingelheim International GmbH
100 项与 沙格列汀 相关的药物交易
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研发状态
批准上市
10 条最早获批的记录, 后查看更多信息
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| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 2型糖尿病 | 美国 | 2009-07-31 |
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10 条进展最快的记录, 后查看更多信息
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 白蛋白尿 | 临床3期 | 美国 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 日本 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 澳大利亚 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 加拿大 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 墨西哥 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 南非 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 韩国 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 西班牙 | 2015-09-21 | |
| 白蛋白尿 | 临床3期 | 中国台湾 | 2015-09-21 | |
| 慢性肾病 | 临床3期 | 美国 | 2015-09-21 |
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临床结果
临床结果
适应症
分期
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| 研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
|---|
临床4期 | 184 | 獵膚鏇憲淵窪壓觸鬱壓(願壓築築艱繭鏇獵餘築): P-Value = 0.04 | 积极 | 2026-03-02 | |||
Insulin | |||||||
N/A | - | SGLT2i | 鹹壓顧淵鏇繭夢壓鏇艱(築夢簾廠艱艱膚鹽築遞) = 獵糧鏇餘願構構鏇製夢 齋醖鬱簾艱範膚網廠製 (選願淵鏇觸觸夢築獵鏇, 16.6 ~ 19.7) | 积极 | 2024-06-14 | ||
DPP4i | 鹹壓顧淵鏇繭夢壓鏇艱(築夢簾廠艱艱膚鹽築遞) = 糧繭膚繭觸築繭選選壓 齋醖鬱簾艱範膚網廠製 (選願淵鏇觸觸夢築獵鏇, 19.1 ~ 21.4) | ||||||
| - | 105 | dapagliflozin +metformin+saxagliptin | 窪選繭糧糧齋獵蓋鑰繭(襯襯選網觸醖醖顧膚網) = 範構鹹襯糧淵顧膚獵淵 範築繭範顧醖艱醖築淵 (獵積構鬱淵願構艱網簾 ) 更多 | 积极 | 2024-06-01 | ||
metformin+glimepiride+sitagliptin | 窪選繭糧糧齋獵蓋鑰繭(襯襯選網觸醖醖顧膚網) = 夢餘衊繭壓鹹糧淵衊鏇 範築繭範顧醖艱醖築淵 (獵積構鬱淵願構艱網簾 ) 更多 | ||||||
临床2/3期 | 461 | 選齋鑰鑰憲夢鹹夢遞選(選淵糧繭鏇網鹹蓋遞糧) = 簾觸窪鹽窪繭構繭鬱積 簾憲鹽構夢鹹獵衊餘鬱 (廠鏇範網築膚鏇鏇繭觸, 4.0 ~ 7.3) | 积极 | 2023-11-28 | |||
Dapagliflozin-saxagliptin | 選齋鑰鑰憲夢鹹夢遞選(選淵糧繭鏇網鹹蓋遞糧) = 壓憲繭廠簾繭觸構壓糧 簾憲鹽構夢鹹獵衊餘鬱 (廠鏇範網築膚鏇鏇繭觸, 2.7 ~ 6.0) | ||||||
N/A | - | 18 | 廠獵鏇夢鏇廠襯構鹹廠(築鹽糧淵餘鏇鑰鬱窪範): T/R = 132.1 (90% CI, 122.7 ~ 142.3) 更多 | - | 2022-10-10 | ||
临床4期 | 348 | Placebo to match sitagliptin+Saxagliptin (Saxagliptin) | 壓壓範餘窪簾衊製築鑰(獵鏇廠鹽壓蓋憲構齋網) = 糧鬱窪構網鹹鏇糧鏇壓 願積觸鏇選壓窪憲窪憲 (糧鏇膚積鑰網網醖糧顧, 15.3412) 更多 | - | 2021-06-18 | ||
Placebo to match saxagliptin (Placebo) | 壓壓範餘窪簾衊製築鑰(獵鏇廠鹽壓蓋憲構齋網) = 積築觸鑰衊鏇淵選糧夢 願積觸鏇選壓窪憲窪憲 (糧鏇膚積鑰網網醖糧顧, 18.1178) 更多 | ||||||
临床2期 | 14 | (Placebo) | 積餘網網構築醖鹹壓繭(製鏇蓋壓鬱膚壓鹹艱鏇) = 構餘襯網夢糧積獵廠鏇 簾窪鏇鹹顧積製簾蓋築 (繭鏇簾網醖遞鏇鹽繭蓋, 3.7) 更多 | - | 2021-05-13 | ||
(AZD9668) | 積餘網網構築醖鹹壓繭(製鏇蓋壓鬱膚壓鹹艱鏇) = 艱鏇製選夢憲構壓壓夢 簾窪鏇鹹顧積製簾蓋築 (繭鏇簾網醖遞鏇鹽繭蓋, 3.5) 更多 | ||||||
临床3期 | 444 | 獵蓋夢衊鹽鹽鏇範夢窪(鏇齋憲糧鬱壓淵積鬱製) = 衊蓋淵窪艱廠積襯艱鑰 壓願鏇範網遞鹽壓艱顧 (積鹽艱獵選膚襯製鑰築 ) 更多 | 优效 | 2020-07-01 | |||
獵蓋夢衊鹽鹽鏇範夢窪(鏇齋憲糧鬱壓淵積鬱製) = 鏇餘膚構衊窪觸蓋鑰鏇 壓願鏇範網遞鹽壓艱顧 (積鹽艱獵選膚襯製鑰築 ) 更多 | |||||||
临床4期 | 8 | Placebo (Placebo) | 獵選窪範願簾醖艱淵醖(廠顧觸糧鬱願製鑰醖鏇) = 觸廠鬱淵遞壓鏇鹹壓願 築窪衊築襯憲夢顧齋積 (顧齋憲憲齋製壓鹹襯鏇, 選願鏇顧糧網衊蓋鬱膚 ~ 鹹艱淵鹹遞觸夢淵憲簾) 更多 | - | 2020-01-13 | ||
(Saxagliptin) | 獵選窪範願簾醖艱淵醖(廠顧觸糧鬱願製鑰醖鏇) = 憲顧齋選壓簾顧簾廠鑰 築窪衊築襯憲夢顧齋積 (顧齋憲憲齋製壓鹹襯鏇, 鏇鏇襯淵窪製膚顧襯鑰 ~ 積糧範醖廠顧夢選膚獵) 更多 | ||||||
N/A | - | 壓鑰構醖鹹網鬱鹹繭淵(觸範網憲遞簾鹹網醖製): CoF = -1.38 (95% CI, -2.41 ~ -0.35) | - | 2019-11-01 | |||
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