1区 · 医学
Article
作者: Xega, Kristina ; England, Dylan ; Shapiro, Gary ; Lightcap, Eric S. ; Milhollen, Michael A. ; Pulukuri, Sai M. ; Khattar, Mithun ; Minissale, James ; Shah, Pooja ; Fu, Yu ; Yang, Xiaofeng ; Hatton, Beryl A. ; Fuchs, Serge Y. ; Garnsey, James J. ; Yu, Pengfei ; Shinde, Vaishali ; Zhang, Hongru ; He, Xingyue ; Langston, Steve ; Imaichi, Hisashi ; Gavin, James M. ; Song, Keli ; Li, Cong ; Galvin, Katherine ; Huszar, Dennis ; Koenig, Erik ; Grossman, Stephen ; Lu, Zhen ; Klinghoffer, Richard A. ; Riceberg, Jessica
TAK-981, a first-in-class small-molecule SUMOylation inhibitor, activates type I interferon signaling to promote antitumor immune responses in mice.